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Search of human proteins with 14042945
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14042945 beta-amyloid binding protein precursor [Homo
sapiens]
(207 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14042945 beta-amyloid binding protein precursor [Homo sapiens] 433 e-122
gi|91807119 TM2 domain containing 3 isoform b [Homo sapiens] 77 8e-15
gi|91807117 TM2 domain containing 3 isoform a [Homo sapiens] 77 8e-15
gi|17865797 TM2 domain containing 2 isoform a [Homo sapiens] 50 2e-06
gi|66932897 TM2 domain containing 2 isoform b [Homo sapiens] 48 5e-06
gi|66932895 TM2 domain containing 2 isoform b [Homo sapiens] 48 5e-06
gi|66932893 TM2 domain containing 2 isoform b [Homo sapiens] 48 5e-06
gi|116284392 mucin 2 precursor [Homo sapiens] 29 3.2
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens] 29 3.2
gi|9910460 nitrilase family, member 2 [Homo sapiens] 29 3.2
gi|16554449 zonadhesin isoform 3 [Homo sapiens] 28 7.2
gi|27881494 zonadhesin isoform 6 [Homo sapiens] 28 7.2
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [... 27 9.4
gi|12545408 RAS p21 protein activator 2 [Homo sapiens] 27 9.4
>gi|14042945 beta-amyloid binding protein precursor [Homo sapiens]
Length = 207
Score = 433 bits (1113), Expect = e-122
Identities = 207/207 (100%), Positives = 207/207 (100%)
Query: 1 MAAAWPSGPSAPEAVTARLVGVLWFVSVTTGPWGAVATSAGGEESLKCEDLKVGQYICKD 60
MAAAWPSGPSAPEAVTARLVGVLWFVSVTTGPWGAVATSAGGEESLKCEDLKVGQYICKD
Sbjct: 1 MAAAWPSGPSAPEAVTARLVGVLWFVSVTTGPWGAVATSAGGEESLKCEDLKVGQYICKD 60
Query: 61 PKINDATQEPVNCTNYTAHVSCFPAPNITCKDSSGNETHFTGNEVGFFKPISCRNVNGYS 120
PKINDATQEPVNCTNYTAHVSCFPAPNITCKDSSGNETHFTGNEVGFFKPISCRNVNGYS
Sbjct: 61 PKINDATQEPVNCTNYTAHVSCFPAPNITCKDSSGNETHFTGNEVGFFKPISCRNVNGYS 120
Query: 121 YKVAVALSLFLGWLGADRFYLGYPALGLLKFCTVGFCGIGSLIDFILISMQIVGPSDGSS 180
YKVAVALSLFLGWLGADRFYLGYPALGLLKFCTVGFCGIGSLIDFILISMQIVGPSDGSS
Sbjct: 121 YKVAVALSLFLGWLGADRFYLGYPALGLLKFCTVGFCGIGSLIDFILISMQIVGPSDGSS 180
Query: 181 YIIDYYGTRLTRLSITNETFRKTQLYP 207
YIIDYYGTRLTRLSITNETFRKTQLYP
Sbjct: 181 YIIDYYGTRLTRLSITNETFRKTQLYP 207
>gi|91807119 TM2 domain containing 3 isoform b [Homo sapiens]
Length = 221
Score = 77.4 bits (189), Expect = 8e-15
Identities = 53/116 (45%), Positives = 65/116 (56%), Gaps = 12/116 (10%)
Query: 73 CTNYTA--HVSC----FPAPNITCKDSSGNETHFTGNEVGFFKPISCRNVNGYSYKVAVA 126
CTN T+ VSC +PA N T +D H GN F K + C GY + A+A
Sbjct: 112 CTNSTSCMTVSCPRQRYPA-NCTVRD----HVHCLGNRT-FPKMLYCNWTGGYKWSTALA 165
Query: 127 LSLFLGWLGADRFYLGYPALGLLKFCTVGFCGIGSLIDFILISMQIVGPSDGSSYI 182
LS+ LG GADRFYLG GL K + G GI +LID +LI + VGP+DGS YI
Sbjct: 166 LSITLGGFGADRFYLGQWREGLGKLFSFGGLGIWTLIDVLLIGVGYVGPADGSLYI 221
>gi|91807117 TM2 domain containing 3 isoform a [Homo sapiens]
Length = 247
Score = 77.4 bits (189), Expect = 8e-15
Identities = 53/116 (45%), Positives = 65/116 (56%), Gaps = 12/116 (10%)
Query: 73 CTNYTA--HVSC----FPAPNITCKDSSGNETHFTGNEVGFFKPISCRNVNGYSYKVAVA 126
CTN T+ VSC +PA N T +D H GN F K + C GY + A+A
Sbjct: 138 CTNSTSCMTVSCPRQRYPA-NCTVRD----HVHCLGNRT-FPKMLYCNWTGGYKWSTALA 191
Query: 127 LSLFLGWLGADRFYLGYPALGLLKFCTVGFCGIGSLIDFILISMQIVGPSDGSSYI 182
LS+ LG GADRFYLG GL K + G GI +LID +LI + VGP+DGS YI
Sbjct: 192 LSITLGGFGADRFYLGQWREGLGKLFSFGGLGIWTLIDVLLIGVGYVGPADGSLYI 247
>gi|17865797 TM2 domain containing 2 isoform a [Homo sapiens]
Length = 214
Score = 49.7 bits (117), Expect = 2e-06
Identities = 46/163 (28%), Positives = 66/163 (40%), Gaps = 10/163 (6%)
Query: 31 GPWGAVATSAGGEES--LKCEDLKVGQYICKDP--KINDATQEP---VNCTNYTAHV-SC 82
GP GA + G S + C L C+DP + +AT C + S
Sbjct: 54 GPGGAASWEYGDPHSPVILCSYLPDEFIECEDPVDHVGNATASQELGYGCLKFGGQAYSD 113
Query: 83 FPAPNITCKDSSGNETHFTGNEVGFFKPISCRNVNGYSYKVAVALSLFLGWLGADRFYLG 142
++ C G E + KP C G+ + + S FLG G DRF LG
Sbjct: 114 VEHTSVQCHALDGIECASPRTFLRENKP--CIKYTGHYFITTLLYSFFLGCFGVDRFCLG 171
Query: 143 YPALGLLKFCTVGFCGIGSLIDFILISMQIVGPSDGSSYIIDY 185
+ + K T+G GI +D IL+ + PSDGS++ Y
Sbjct: 172 HTGTAVGKLLTLGGLGIWWFVDLILLITGGLMPSDGSNWCTVY 214
>gi|66932897 TM2 domain containing 2 isoform b [Homo sapiens]
Length = 171
Score = 48.1 bits (113), Expect = 5e-06
Identities = 26/73 (35%), Positives = 37/73 (50%)
Query: 113 CRNVNGYSYKVAVALSLFLGWLGADRFYLGYPALGLLKFCTVGFCGIGSLIDFILISMQI 172
C G+ + + S FLG G DRF LG+ + K T+G GI +D IL+
Sbjct: 99 CIKYTGHYFITTLLYSFFLGCFGVDRFCLGHTGTAVGKLLTLGGLGIWWFVDLILLITGG 158
Query: 173 VGPSDGSSYIIDY 185
+ PSDGS++ Y
Sbjct: 159 LMPSDGSNWCTVY 171
>gi|66932895 TM2 domain containing 2 isoform b [Homo sapiens]
Length = 171
Score = 48.1 bits (113), Expect = 5e-06
Identities = 26/73 (35%), Positives = 37/73 (50%)
Query: 113 CRNVNGYSYKVAVALSLFLGWLGADRFYLGYPALGLLKFCTVGFCGIGSLIDFILISMQI 172
C G+ + + S FLG G DRF LG+ + K T+G GI +D IL+
Sbjct: 99 CIKYTGHYFITTLLYSFFLGCFGVDRFCLGHTGTAVGKLLTLGGLGIWWFVDLILLITGG 158
Query: 173 VGPSDGSSYIIDY 185
+ PSDGS++ Y
Sbjct: 159 LMPSDGSNWCTVY 171
>gi|66932893 TM2 domain containing 2 isoform b [Homo sapiens]
Length = 171
Score = 48.1 bits (113), Expect = 5e-06
Identities = 26/73 (35%), Positives = 37/73 (50%)
Query: 113 CRNVNGYSYKVAVALSLFLGWLGADRFYLGYPALGLLKFCTVGFCGIGSLIDFILISMQI 172
C G+ + + S FLG G DRF LG+ + K T+G GI +D IL+
Sbjct: 99 CIKYTGHYFITTLLYSFFLGCFGVDRFCLGHTGTAVGKLLTLGGLGIWWFVDLILLITGG 158
Query: 173 VGPSDGSSYIIDY 185
+ PSDGS++ Y
Sbjct: 159 LMPSDGSNWCTVY 171
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 28.9 bits (63), Expect = 3.2
Identities = 18/61 (29%), Positives = 28/61 (45%), Gaps = 6/61 (9%)
Query: 45 SLKCEDLKV------GQYICKDPKINDATQEPVNCTNYTAHVSCFPAPNITCKDSSGNET 98
SL+C L+ Q IC D + + V C ++ + +C PA TCK SS +
Sbjct: 4728 SLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQN 4787
Query: 99 H 99
+
Sbjct: 4788 N 4788
>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
Length = 2639
Score = 28.9 bits (63), Expect = 3.2
Identities = 18/61 (29%), Positives = 28/61 (45%), Gaps = 6/61 (9%)
Query: 45 SLKCEDLKV------GQYICKDPKINDATQEPVNCTNYTAHVSCFPAPNITCKDSSGNET 98
SL+C L+ Q IC D + + V C ++ + +C PA TCK SS +
Sbjct: 2188 SLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQN 2247
Query: 99 H 99
+
Sbjct: 2248 N 2248
>gi|9910460 nitrilase family, member 2 [Homo sapiens]
Length = 276
Score = 28.9 bits (63), Expect = 3.2
Identities = 12/30 (40%), Positives = 15/30 (50%)
Query: 22 VLWFVSVTTGPWGAVATSAGGEESLKCEDL 51
V W S PWG V AG EE++ D+
Sbjct: 217 VAWGHSTVVNPWGEVLAKAGTEEAIVYSDI 246
>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
Length = 2812
Score = 27.7 bits (60), Expect = 7.2
Identities = 15/60 (25%), Positives = 28/60 (46%), Gaps = 5/60 (8%)
Query: 41 GGEESLKCEDLKVGQYIC-----KDPKINDATQEPVNCTNYTAHVSCFPAPNITCKDSSG 95
GG C+ L+ C K P +++ P+ C Y+++ +C P+ + +C D G
Sbjct: 2174 GGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDG 2233
>gi|27881494 zonadhesin isoform 6 [Homo sapiens]
Length = 2721
Score = 27.7 bits (60), Expect = 7.2
Identities = 15/60 (25%), Positives = 28/60 (46%), Gaps = 5/60 (8%)
Query: 41 GGEESLKCEDLKVGQYIC-----KDPKINDATQEPVNCTNYTAHVSCFPAPNITCKDSSG 95
GG C+ L+ C K P +++ P+ C Y+++ +C P+ + +C D G
Sbjct: 2174 GGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDG 2233
>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo
sapiens]
Length = 3969
Score = 27.3 bits (59), Expect = 9.4
Identities = 24/84 (28%), Positives = 34/84 (40%), Gaps = 16/84 (19%)
Query: 39 SAGGEESLKCEDLKVGQYICKDPKI------NDATQEPVNCTNYTAHVSCFPAPN----- 87
S+GGEE L +L + C PKI +D T+ + T T S P N
Sbjct: 2690 SSGGEERLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENG 2749
Query: 88 -----ITCKDSSGNETHFTGNEVG 106
I + +G + H T + VG
Sbjct: 2750 TENLKIDRPEDAGEKEHVTKSSVG 2773
>gi|12545408 RAS p21 protein activator 2 [Homo sapiens]
Length = 849
Score = 27.3 bits (59), Expect = 9.4
Identities = 15/48 (31%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
Query: 9 PSAPEAVTARLVGVLWFVSVTTGPWGAVATSAGG-EESLKCEDLKVGQ 55
P P+A T R + ++ T G WG+++ S +E+ CE K+ Q
Sbjct: 527 PHHPDAQTIRTLTLISKTIQTLGSWGSLSKSKSSFKETFMCEFFKMFQ 574
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.138 0.440
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,382,117
Number of Sequences: 37866
Number of extensions: 369709
Number of successful extensions: 676
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 664
Number of HSP's gapped (non-prelim): 18
length of query: 207
length of database: 18,247,518
effective HSP length: 98
effective length of query: 109
effective length of database: 14,536,650
effective search space: 1584494850
effective search space used: 1584494850
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.