Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 7657591

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7657591 solute carrier family 7, member 9 [Homo sapiens]
         (487 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|187423910 solute carrier family 7, member 9 [Homo sapiens]         964   0.0  
gi|7657591 solute carrier family 7, member 9 [Homo sapiens]           964   0.0  
gi|7657683 solute carrier family 7, (cationic amino acid transpo...   419   e-117
gi|71979932 solute carrier family 7 (cationic amino acid transpo...   415   e-116
gi|115648063 solute carrier family 7 (cationic amino acid transp...   411   e-115
gi|115648022 solute carrier family 7 (cationic amino acid transp...   411   e-115
gi|186910308 solute carrier family 7 member 7 [Homo sapiens]          410   e-114
gi|186910306 solute carrier family 7 member 7 [Homo sapiens]          410   e-114
gi|186910304 solute carrier family 7 member 7 [Homo sapiens]          410   e-114
gi|33286428 solute carrier family 7 (cationic amino acid transpo...   387   e-107
gi|9790235 solute carrier family 7, member 10 [Homo sapiens]          369   e-102
gi|71999149 solute carrier family 7, (cationic amino acid transp...   254   1e-67
gi|33286430 solute carrier family 7 (cationic amino acid transpo...   222   7e-58
gi|110347453 solute carrier family 7 (cationic amino acid transp...   125   7e-29
gi|114326550 solute carrier family 7 (cationic amino acid transp...   103   5e-22
gi|114326544 solute carrier family 7 (cationic amino acid transp...   103   5e-22
gi|134304858 solute carrier family 7, member 2 isoform 2 [Homo s...   102   1e-21
gi|4507047 solute carrier family 7 (cationic amino acid transpor...   100   2e-21
gi|109948288 solute carrier family 7, member 2 isoform 1 [Homo s...   100   4e-21
gi|181337167 solute carrier family 7 (cationic amino acid transp...    86   8e-17
gi|198041678 solute carrier family 12 (potassium-chloride transp...    39   0.011
gi|11968148 solute carrier family 12 (potassium-chloride transpo...    39   0.011
gi|110224458 solute carrier family 12, member 6 isoform e [Homo ...    35   0.15 
gi|110224456 solute carrier family 12, member 6 isoform d [Homo ...    35   0.15 
gi|110224454 solute carrier family 12, member 6 isoform c [Homo ...    35   0.15 
gi|110224452 solute carrier family 12, member 6 isoform c [Homo ...    35   0.15 
gi|4826780 solute carrier family 12, member 6 isoform b [Homo sa...    35   0.15 
gi|110224449 solute carrier family 12, member 6 isoform a [Homo ...    35   0.15 
gi|41327726 nicotinic acetylcholine receptor beta 1 subunit prec...    33   0.45 
gi|31881740 solute carrier family 12 (potassium/chloride transpo...    33   0.45 

>gi|187423910 solute carrier family 7, member 9 [Homo sapiens]
          Length = 487

 Score =  964 bits (2491), Expect = 0.0
 Identities = 487/487 (100%), Positives = 487/487 (100%)

Query: 1   MGDTGLRKRREDEKSIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTE 60
           MGDTGLRKRREDEKSIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTE
Sbjct: 1   MGDTGLRKRREDEKSIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTE 60

Query: 61  AVGPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVI 120
           AVGPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVI
Sbjct: 61  AVGPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVI 120

Query: 121 KPTSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIF 180
           KPTSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIF
Sbjct: 121 KPTSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIF 180

Query: 181 TAAKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNY 240
           TAAKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNY
Sbjct: 181 TAAKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNY 240

Query: 241 ITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYP 300
           ITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYP
Sbjct: 241 ITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYP 300

Query: 301 ASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGI 360
           ASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGI
Sbjct: 301 ASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGI 360

Query: 361 IATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLI 420
           IATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLI
Sbjct: 361 IATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLI 420

Query: 421 SVFLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVHYKFGWAQKISKPITMHLQMLMEVV 480
           SVFLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVHYKFGWAQKISKPITMHLQMLMEVV
Sbjct: 421 SVFLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVHYKFGWAQKISKPITMHLQMLMEVV 480

Query: 481 PPEEDPE 487
           PPEEDPE
Sbjct: 481 PPEEDPE 487


>gi|7657591 solute carrier family 7, member 9 [Homo sapiens]
          Length = 487

 Score =  964 bits (2491), Expect = 0.0
 Identities = 487/487 (100%), Positives = 487/487 (100%)

Query: 1   MGDTGLRKRREDEKSIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTE 60
           MGDTGLRKRREDEKSIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTE
Sbjct: 1   MGDTGLRKRREDEKSIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTE 60

Query: 61  AVGPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVI 120
           AVGPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVI
Sbjct: 61  AVGPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVI 120

Query: 121 KPTSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIF 180
           KPTSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIF
Sbjct: 121 KPTSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIF 180

Query: 181 TAAKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNY 240
           TAAKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNY
Sbjct: 181 TAAKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNY 240

Query: 241 ITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYP 300
           ITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYP
Sbjct: 241 ITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYP 300

Query: 301 ASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGI 360
           ASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGI
Sbjct: 301 ASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGI 360

Query: 361 IATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLI 420
           IATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLI
Sbjct: 361 IATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLI 420

Query: 421 SVFLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVHYKFGWAQKISKPITMHLQMLMEVV 480
           SVFLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVHYKFGWAQKISKPITMHLQMLMEVV
Sbjct: 421 SVFLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVHYKFGWAQKISKPITMHLQMLMEVV 480

Query: 481 PPEEDPE 487
           PPEEDPE
Sbjct: 481 PPEEDPE 487


>gi|7657683 solute carrier family 7, (cationic amino acid
           transporter, y+ system) member 11 [Homo sapiens]
          Length = 501

 Score =  419 bits (1076), Expect = e-117
 Identities = 210/475 (44%), Positives = 312/475 (65%), Gaps = 6/475 (1%)

Query: 15  SIQSQEP---KTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAA 71
           S+ ++EP   +   L++++ L+ G+SII+GTIIG+GIF+SPK VL NT +VG  L IW  
Sbjct: 26  SLGNKEPPGQEKVQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTGSVGMSLTIWTV 85

Query: 72  CGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLS 131
           CGVL+  GAL +AELGT I KSGG Y Y++E +GP+PA++  W  L++I+P + A+I L+
Sbjct: 86  CGVLSLFGALSYAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELLIIRPAATAVISLA 145

Query: 132 FSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAII 191
           F  Y+  PF++ C+ P++ +K + A  I  +  +NS+SV   + +Q   T  KL  + II
Sbjct: 146 FGRYILEPFFIQCEIPELAIKLITAVGITVVMVLNSMSVSWSARIQIFLTFCKLTAILII 205

Query: 192 IISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRN 251
           I+ G++ L +G T+NF ++F G   S+  + LAFY G++AY GW  LN++TEE+ NP + 
Sbjct: 206 IVPGVMQLIKGQTQNFKDAFSGRDSSITRLPLAFYYGMYAYAGWFYLNFVTEEVENPEKT 265

Query: 252 LPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAF 311
           +PLAI I + +VT  Y+L NV+YFT + A ELL S AVAVTF +R+L   S  VP+FVA 
Sbjct: 266 IPLAICISMAIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSERLLGNFSLAVPIFVAL 325

Query: 312 STIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDI 371
           S  G+ NG  F   RL YVA REGH+ ++LS I VR+ TP PA+I    +  I +  GD+
Sbjct: 326 SCFGSMNGGVFAVSRLFYVASREGHLPEILSMIHVRKHTPLPAVIVLHPLTMIMLFSGDL 385

Query: 372 NSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIIS 431
           +SL+N+ SFA WLF GL + GLI +R+   ++ RP KVP+ IP L +   +F+V   + S
Sbjct: 386 DSLLNFLSFARWLFIGLAVAGLIYLRYKCPDMHRPFKVPLFIPALFSFTCLFMVALSLYS 445

Query: 432 KPTWEYLYCVLFILSGLLFYFLFVHY--KFGWAQKISKPITMHLQMLMEVVPPEE 484
            P    +  V+  L+G+  Y+LF+ +  K  W + +S+ IT  LQ+++EVVP E+
Sbjct: 446 DPFSTGIGFVI-TLTGVPAYYLFIIWDKKPRWFRIMSEKITRTLQIILEVVPEED 499


>gi|71979932 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 5 [Homo sapiens]
          Length = 507

 Score =  415 bits (1066), Expect = e-116
 Identities = 214/473 (45%), Positives = 306/473 (64%), Gaps = 5/473 (1%)

Query: 15  SIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGV 74
           S  + E +  +LQ+ + L++G++IIVGTIIGSGIFV+P  VL    + G  L++WAACGV
Sbjct: 35  SAPAGEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGV 94

Query: 75  LATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLSFSE 134
            + +GALC+AELGT I+KSGG+Y Y++E YG +PA+L  W  L++I+P+S  I+ L F+ 
Sbjct: 95  FSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFAT 154

Query: 135 YVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAIIIIS 194
           Y+  P +  C  P+   K +A   +L ++ VN  SV+  + VQ+ F AAKL+ +A+II+ 
Sbjct: 155 YLLKPLFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILL 214

Query: 195 GLVLLAQGNTKNFDN--SFEGAQLSVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNL 252
           G V + +G+  N D   SFEG +L VG I LA Y+GL+AY GWN LN++TEE+ NPYRNL
Sbjct: 215 GFVQIGKGDVSNLDPNFSFEGTKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNL 274

Query: 253 PLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFS 312
           PLAIII +P+VT  Y+L N++YFT ++  ++L S+AVAV FG+  L   SWI+P+FV  S
Sbjct: 275 PLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLS 334

Query: 313 TIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDIN 372
             G+ NG+ FT+ RL +V  REGH+  +LS I  + LTP P+++F  ++  +Y    DI 
Sbjct: 335 CFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIF 394

Query: 373 SLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIISK 432
           S++N+FSF  WL   L I+G+I +R  + ELERPIKV + +PV   L  +FL+       
Sbjct: 395 SVINFFSFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVSFWKT 454

Query: 433 PTWEYLYCVLFILSGLLFYFLFVHYKF--GWAQKISKPITMHLQMLMEVVPPE 483
           P  E       ILSGL  YF  V +K    W  +     T+  Q LM+VVP E
Sbjct: 455 PV-ECGIGFTIILSGLPVYFFGVWWKNKPKWLLQGIFSTTVLCQKLMQVVPQE 506


>gi|115648063 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 6 [Homo sapiens]
          Length = 515

 Score =  411 bits (1057), Expect = e-115
 Identities = 201/454 (44%), Positives = 303/454 (66%), Gaps = 1/454 (0%)

Query: 3   DTGLRKRREDEKSIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAV 62
           +T   +  ED  S   +  +T  L+KE+ L++G+S++VG +IGSGIFVSPK VL +T + 
Sbjct: 18  NTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASY 77

Query: 63  GPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKP 122
           G  LI+WA  G+ + +GALC+AELGT ITKSG  Y Y++EA+G   A++  W SL+V++P
Sbjct: 78  GMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEP 137

Query: 123 TSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTA 182
           T  AII ++F+ Y+  P +  C PP +  + LAAA I  ++ VN   V+ G+ VQ+ FT 
Sbjct: 138 TGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTFTY 197

Query: 183 AKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNYIT 242
           AK+V +  II+ GLV L QG++++F ++FEG+   +G +SLA Y+ L++Y GW+ LN++T
Sbjct: 198 AKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLALYSALFSYSGWDTLNFVT 257

Query: 243 EELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPAS 302
           EE++NP RNLPLAI I +P+VT  YIL NV+Y+TV+  +++L S AVAVTF D+     S
Sbjct: 258 EEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGMFS 317

Query: 303 WIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIA 362
           W +P+ VA S  G  N + F + RL +V  REGH+  +LS I + R TP PA++F   +A
Sbjct: 318 WTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCTMA 377

Query: 363 TIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISV 422
            IY+I  D+  L+NYFSF+ W F GL+++G + +R+   +  RP+K+ V  P++  + SV
Sbjct: 378 LIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCICSV 437

Query: 423 FLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVH 456
           FLV+ P+ +  T   L  +   LSG+ FYF+ V+
Sbjct: 438 FLVIVPLFT-DTINSLIGIGIALSGVPFYFMGVY 470


>gi|115648022 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 6 [Homo sapiens]
          Length = 515

 Score =  411 bits (1057), Expect = e-115
 Identities = 201/454 (44%), Positives = 303/454 (66%), Gaps = 1/454 (0%)

Query: 3   DTGLRKRREDEKSIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAV 62
           +T   +  ED  S   +  +T  L+KE+ L++G+S++VG +IGSGIFVSPK VL +T + 
Sbjct: 18  NTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASY 77

Query: 63  GPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKP 122
           G  LI+WA  G+ + +GALC+AELGT ITKSG  Y Y++EA+G   A++  W SL+V++P
Sbjct: 78  GMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEP 137

Query: 123 TSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTA 182
           T  AII ++F+ Y+  P +  C PP +  + LAAA I  ++ VN   V+ G+ VQ+ FT 
Sbjct: 138 TGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTFTY 197

Query: 183 AKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNYIT 242
           AK+V +  II+ GLV L QG++++F ++FEG+   +G +SLA Y+ L++Y GW+ LN++T
Sbjct: 198 AKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLALYSALFSYSGWDTLNFVT 257

Query: 243 EELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPAS 302
           EE++NP RNLPLAI I +P+VT  YIL NV+Y+TV+  +++L S AVAVTF D+     S
Sbjct: 258 EEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGMFS 317

Query: 303 WIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIA 362
           W +P+ VA S  G  N + F + RL +V  REGH+  +LS I + R TP PA++F   +A
Sbjct: 318 WTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCTMA 377

Query: 363 TIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISV 422
            IY+I  D+  L+NYFSF+ W F GL+++G + +R+   +  RP+K+ V  P++  + SV
Sbjct: 378 LIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCICSV 437

Query: 423 FLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVH 456
           FLV+ P+ +  T   L  +   LSG+ FYF+ V+
Sbjct: 438 FLVIVPLFT-DTINSLIGIGIALSGVPFYFMGVY 470


>gi|186910308 solute carrier family 7 member 7 [Homo sapiens]
          Length = 511

 Score =  410 bits (1053), Expect = e-114
 Identities = 208/474 (43%), Positives = 307/474 (64%), Gaps = 5/474 (1%)

Query: 18  SQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGVLAT 77
           S  P+   L+KE+ L++G+ +IVG +IGSGIFVSPK VL  + + G  L+IWA  G+ + 
Sbjct: 25  SPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVIWAVGGLFSV 84

Query: 78  LGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLSFSEYVC 137
            GALC+AELGT I KSG  Y Y++EA+G   A++  W SL++I+PTS AII ++F+ Y+ 
Sbjct: 85  FGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLIIEPTSQAIIAITFANYMV 144

Query: 138 APFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAIIIISGLV 197
            P +  C  P    + LAAA I  ++ +N   V+ G+ VQ+IFT AK++ +  +I++G+V
Sbjct: 145 QPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLALIAVIVAGIV 204

Query: 198 LLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPLAII 257
            L QG + +F+NSFEG+  +VG I+LA Y+ L++Y GW+ LNY+TEE++NP RNLPL+I 
Sbjct: 205 RLGQGASTHFENSFEGSSFAVGDIALALYSALFSYSGWDTLNYVTEEIKNPERNLPLSIG 264

Query: 258 IGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAA 317
           I +P+VT  YIL NV+Y+TV+   ++L S AVAVTF D++    +WI+PL VA S  G  
Sbjct: 265 ISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGIFNWIIPLSVALSCFGGL 324

Query: 318 NGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNY 377
           N +   A RL +V  REGH+   +  I V R TP P+++F GI+A IY+   DI  L+NY
Sbjct: 325 NASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGIMALIYLCVEDIFQLINY 384

Query: 378 FSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEY 437
           +SF+ W F GL+I+G + +R+   +  RP+K+ V  P++  L ++FLV  P+ S  T   
Sbjct: 385 YSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFCLCTIFLVAVPLYS-DTINS 443

Query: 438 LYCVLFILSGLLFYFLFV----HYKFGWAQKISKPITMHLQMLMEVVPPEEDPE 487
           L  +   LSGL FYFL +    H +  + ++I    T +LQ+L   V  E D E
Sbjct: 444 LIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQVLCMSVAAEMDLE 497


>gi|186910306 solute carrier family 7 member 7 [Homo sapiens]
          Length = 511

 Score =  410 bits (1053), Expect = e-114
 Identities = 208/474 (43%), Positives = 307/474 (64%), Gaps = 5/474 (1%)

Query: 18  SQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGVLAT 77
           S  P+   L+KE+ L++G+ +IVG +IGSGIFVSPK VL  + + G  L+IWA  G+ + 
Sbjct: 25  SPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVIWAVGGLFSV 84

Query: 78  LGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLSFSEYVC 137
            GALC+AELGT I KSG  Y Y++EA+G   A++  W SL++I+PTS AII ++F+ Y+ 
Sbjct: 85  FGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLIIEPTSQAIIAITFANYMV 144

Query: 138 APFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAIIIISGLV 197
            P +  C  P    + LAAA I  ++ +N   V+ G+ VQ+IFT AK++ +  +I++G+V
Sbjct: 145 QPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLALIAVIVAGIV 204

Query: 198 LLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPLAII 257
            L QG + +F+NSFEG+  +VG I+LA Y+ L++Y GW+ LNY+TEE++NP RNLPL+I 
Sbjct: 205 RLGQGASTHFENSFEGSSFAVGDIALALYSALFSYSGWDTLNYVTEEIKNPERNLPLSIG 264

Query: 258 IGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAA 317
           I +P+VT  YIL NV+Y+TV+   ++L S AVAVTF D++    +WI+PL VA S  G  
Sbjct: 265 ISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGIFNWIIPLSVALSCFGGL 324

Query: 318 NGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNY 377
           N +   A RL +V  REGH+   +  I V R TP P+++F GI+A IY+   DI  L+NY
Sbjct: 325 NASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGIMALIYLCVEDIFQLINY 384

Query: 378 FSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEY 437
           +SF+ W F GL+I+G + +R+   +  RP+K+ V  P++  L ++FLV  P+ S  T   
Sbjct: 385 YSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFCLCTIFLVAVPLYS-DTINS 443

Query: 438 LYCVLFILSGLLFYFLFV----HYKFGWAQKISKPITMHLQMLMEVVPPEEDPE 487
           L  +   LSGL FYFL +    H +  + ++I    T +LQ+L   V  E D E
Sbjct: 444 LIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQVLCMSVAAEMDLE 497


>gi|186910304 solute carrier family 7 member 7 [Homo sapiens]
          Length = 511

 Score =  410 bits (1053), Expect = e-114
 Identities = 208/474 (43%), Positives = 307/474 (64%), Gaps = 5/474 (1%)

Query: 18  SQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGVLAT 77
           S  P+   L+KE+ L++G+ +IVG +IGSGIFVSPK VL  + + G  L+IWA  G+ + 
Sbjct: 25  SPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVIWAVGGLFSV 84

Query: 78  LGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLSFSEYVC 137
            GALC+AELGT I KSG  Y Y++EA+G   A++  W SL++I+PTS AII ++F+ Y+ 
Sbjct: 85  FGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLIIEPTSQAIIAITFANYMV 144

Query: 138 APFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAIIIISGLV 197
            P +  C  P    + LAAA I  ++ +N   V+ G+ VQ+IFT AK++ +  +I++G+V
Sbjct: 145 QPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLALIAVIVAGIV 204

Query: 198 LLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPLAII 257
            L QG + +F+NSFEG+  +VG I+LA Y+ L++Y GW+ LNY+TEE++NP RNLPL+I 
Sbjct: 205 RLGQGASTHFENSFEGSSFAVGDIALALYSALFSYSGWDTLNYVTEEIKNPERNLPLSIG 264

Query: 258 IGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAA 317
           I +P+VT  YIL NV+Y+TV+   ++L S AVAVTF D++    +WI+PL VA S  G  
Sbjct: 265 ISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGIFNWIIPLSVALSCFGGL 324

Query: 318 NGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNY 377
           N +   A RL +V  REGH+   +  I V R TP P+++F GI+A IY+   DI  L+NY
Sbjct: 325 NASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGIMALIYLCVEDIFQLINY 384

Query: 378 FSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEY 437
           +SF+ W F GL+I+G + +R+   +  RP+K+ V  P++  L ++FLV  P+ S  T   
Sbjct: 385 YSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFCLCTIFLVAVPLYS-DTINS 443

Query: 438 LYCVLFILSGLLFYFLFV----HYKFGWAQKISKPITMHLQMLMEVVPPEEDPE 487
           L  +   LSGL FYFL +    H +  + ++I    T +LQ+L   V  E D E
Sbjct: 444 LIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQVLCMSVAAEMDLE 497


>gi|33286428 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 8 isoform a [Homo
           sapiens]
          Length = 535

 Score =  387 bits (993), Expect = e-107
 Identities = 199/440 (45%), Positives = 292/440 (66%), Gaps = 10/440 (2%)

Query: 25  SLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGVLATLGALCFA 84
           +L+KE+GL+S   IIVG IIGSGIFVSPK VL N  +VG  LI+W   G +  +GALC+A
Sbjct: 35  ALKKEIGLVSACGIIVGNIIGSGIFVSPKGVLENAGSVGLALIVWIVTGFITVVGALCYA 94

Query: 85  ELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLSFSEYVCAPFYVGC 144
           ELG  I KSGG+Y Y+ + +G +  +L  W +++VI PT+ A+I L+FS YV  P +  C
Sbjct: 95  ELGVTIPKSGGDYSYVKDIFGGLAGFLRLWIAVLVIYPTNQAVIALTFSNYVLQPLFPTC 154

Query: 145 KPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAIIIISGLVLLAQGNT 204
            PP+  ++ LAA  +L ++ VN  SVR  + VQ+IFTA KL+ +A+III G+V + +G  
Sbjct: 155 FPPESGLRLLAAICLLLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGIVQICKGEY 214

Query: 205 KNFD--NSFEGAQL-SVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPLAIIIGIP 261
              +  N+FE  Q   +G ++LAF  G +AY GWN LNY+TEEL +PY+NLP AI I IP
Sbjct: 215 FWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKNLPRAIFISIP 274

Query: 262 LVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAANGTC 321
           LVT  Y+  NV+Y T M+  ELL S AVAVTFG+++L   +WI+P+ VA ST G  NG+ 
Sbjct: 275 LVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVALSTFGGVNGSL 334

Query: 322 FTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNYFSFA 381
           FT+ RL +   REGH+  VL+ I V+R TP PA++F  I   + ++  D+ +L+NY  F 
Sbjct: 335 FTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDMYTLINYVGFI 394

Query: 382 AWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEYLYC- 440
            +LFYG+T+ G IV+R+ + ++ RPIK+ ++ P++  L   FL++  + S+P    + C 
Sbjct: 395 NYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLWSEP----VVCG 450

Query: 441 --VLFILSGLLFYFLFVHYK 458
             +  +L+G+  YFL V+++
Sbjct: 451 IGLAIMLTGVPVYFLGVYWQ 470


>gi|9790235 solute carrier family 7, member 10 [Homo sapiens]
          Length = 523

 Score =  369 bits (946), Expect = e-102
 Identities = 199/471 (42%), Positives = 300/471 (63%), Gaps = 12/471 (2%)

Query: 25  SLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGVLATLGALCFA 84
           +L+KE+GL+S  +II+G IIGSGIF+SPK VL ++ +VG  L +W   G +  LG+LC+A
Sbjct: 35  ALKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHSGSVGLALFVWVLGGGVTALGSLCYA 94

Query: 85  ELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLSFSEYVCAPFYVGC 144
           ELG  I KSGG+Y Y+ E +G +  +L  W++++++ PTS A+I ++FS YV  P +  C
Sbjct: 95  ELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVISMTFSNYVLQPVFPNC 154

Query: 145 KPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAIIIISGLVLLAQGNT 204
            PP    + L+ A ++ ++ VNS SVR  + +Q++FT  KL+ +++II  GL+ + QG+ 
Sbjct: 155 IPPTTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLIIGVGLLQIFQGHF 214

Query: 205 KNF--DNSFEGAQL-SVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPLAIIIGIP 261
           +     N+F      SVG ++LAF  G +A+ GWN LNY+TEE+ +  +NLP AI I IP
Sbjct: 215 EELRPSNAFAFWMTPSVGHLALAFLQGSFAFSGWNFLNYVTEEMVDARKNLPRAIFISIP 274

Query: 262 LVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAANGTC 321
           LVT  Y   N++YFT M+  ELL S AVAVTFG+++L   SW++P+ VA ST G  NG  
Sbjct: 275 LVTFVYTFTNIAYFTAMSPQELLSSNAVAVTFGEKLLGYFSWVMPVSVALSTFGGINGYL 334

Query: 322 FTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNYFSFA 381
           FT  RL +   REGH+  +L+ I VR  TP PA++       + ++ GD  +L+NY SF 
Sbjct: 335 FTYSRLCFSGAREGHLPSLLAMIHVRHCTPIPALLVCCGATAVIMLVGDTYTLINYVSFI 394

Query: 382 AWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEYLYC- 440
            +L YG+TILGL+++R+ R  L RPIKV ++IPV   +   FL++   IS+P    + C 
Sbjct: 395 NYLCYGVTILGLLLLRWRRPALHRPIKVNLLIPVAYLVFWAFLLVFSFISEP----MVCG 450

Query: 441 --VLFILSGLLFYFLFVHY--KFGWAQKISKPITMHLQMLMEVVPPEEDPE 487
             V+ IL+G+  +FL V +  K     ++++ +T   Q L  VV P++ PE
Sbjct: 451 VGVIIILTGVPIFFLGVFWRSKPKCVHRLTESMTHWGQELCFVVYPQDAPE 501


>gi|71999149 solute carrier family 7, (cationic amino acid
           transporter, y+ system) member 13 [Homo sapiens]
          Length = 470

 Score =  254 bits (649), Expect = 1e-67
 Identities = 151/468 (32%), Positives = 246/468 (52%), Gaps = 12/468 (2%)

Query: 26  LQKELGLISGISIIVGTIIGSGIFVSPKSVLS-NTEAVGPCLIIWAACGVLATLGALCFA 84
           L++  G   G S ++  IIG+GIFVSPK VL+ +   VG  L +WA C +LA    LC A
Sbjct: 9   LKRVFGYWWGTSFLLINIIGAGIFVSPKGVLAYSCMNVGVSLCVWAGCAILAMTSTLCSA 68

Query: 85  ELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLSFSEYVCAPFYVGC 144
           E+      SG +Y +L   +G   A+L  W SL +      A   L  +EY   PF+  C
Sbjct: 69  EISISFPCSGAQYYFLKRYFGSTVAFLNLWTSLFLGSGV-VAGQALLLAEYSIQPFFPSC 127

Query: 145 KPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAIIIISGLVLLAQG-- 202
             P++  KCLA A +  +  + S  V+  +++Q   +  K+ I++ I ++G+V L +G  
Sbjct: 128 SVPKLPKKCLALAMLWIVGILTSRGVKEVTWLQIASSVLKVSILSFISLTGVVFLIRGKK 187

Query: 203 -NTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPLAIIIGIP 261
            N + F N+F+     +  +  A + G +AY G      I  EL+ P   +P  I   +P
Sbjct: 188 ENVERFQNAFDAELPDISHLIQAIFQGYFAYSGGACFTLIAGELKKPRTTIPKCIFTALP 247

Query: 262 LVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAANGTC 321
           LVT  Y+L+N+SY TV+T  E+L S AVA+T+ DR     +WI+P  ++ S       + 
Sbjct: 248 LVTVVYLLVNISYLTVLTPREILSSDAVAITWADRAFPSLAWIMPFAISTSLFSNLLISI 307

Query: 322 FTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNYFSFA 381
           F + R IY+A +EG +  + + ++    +P  A++    + ++ II   +  L+NY  F 
Sbjct: 308 FKSSRPIYLASQEGQLPLLFNTLN-SHSSPFTAVLLLVTLGSLAIILTSLIDLINYIFFT 366

Query: 382 AWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEYLYCV 441
             L+  L ++G++  R+    L  P KV +  P+   +I V LV+ P++  P   Y+Y +
Sbjct: 367 GSLWSILLMIGILRRRYQEPNLSIPYKVFLSFPLATIVIDVGLVVIPLVKSPNVHYVYVL 426

Query: 442 LFILSGLLFYFLFVHYK--FGWAQKISKPITMHLQMLMEVVPPEEDPE 487
           L +LSGLLFY   +H+K    W +K    +T +LQ+L  +  P+   E
Sbjct: 427 LLVLSGLLFYIPLIHFKIRLAWFEK----MTCYLQLLFNICLPDVSEE 470


>gi|33286430 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 8 isoform b [Homo
           sapiens]
          Length = 332

 Score =  222 bits (565), Expect = 7e-58
 Identities = 112/254 (44%), Positives = 168/254 (66%), Gaps = 8/254 (3%)

Query: 209 NSFEGAQL-SVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPLAIIIGIPLVTACY 267
           N+FE  Q   +G ++LAF  G +AY GWN LNY+TEEL +PY+NLP AI I IPLVT  Y
Sbjct: 18  NAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVY 77

Query: 268 ILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAANGTCFTAGRL 327
           +  NV+Y T M+  ELL S AVAVTFG+++L   +WI+P+ VA ST G  NG+ FT+ RL
Sbjct: 78  VFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVALSTFGGVNGSLFTSSRL 137

Query: 328 IYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNYFSFAAWLFYG 387
            +   REGH+  VL+ I V+R TP PA++F  I   + ++  D+ +L+NY  F  +LFYG
Sbjct: 138 FFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDMYTLINYVGFINYLFYG 197

Query: 388 LTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEYLYC---VLFI 444
           +T+ G IV+R+ + ++ RPIK+ ++ P++  L   FL++  + S+P    + C   +  +
Sbjct: 198 VTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLWSEP----VVCGIGLAIM 253

Query: 445 LSGLLFYFLFVHYK 458
           L+G+  YFL V+++
Sbjct: 254 LTGVPVYFLGVYWQ 267


>gi|110347453 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 4 [Homo sapiens]
          Length = 635

 Score =  125 bits (315), Expect = 7e-29
 Identities = 99/395 (25%), Positives = 182/395 (46%), Gaps = 27/395 (6%)

Query: 24  TSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLII-WAACGVLATLGALC 82
           TSL++ L  +    + VG ++GSG++V   +V    E  GP +++ +    V + L ALC
Sbjct: 31  TSLRRCLSTLDLTLLGVGGMVGSGLYVLTGAVAK--EVAGPAVLLSFGVAAVASLLAALC 88

Query: 83  FAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLSFSEYVCAPF-- 140
           +AE G  + ++G  Y +   + G + A+L  W ++++      A +  ++S Y+ + F  
Sbjct: 89  YAEFGARVPRTGSAYLFTYVSMGELWAFLIGW-NVLLEYIIGGAAVARAWSGYLDSMFSH 147

Query: 141 --------YVGCKPPQIV---VKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVA 189
                   +VG     ++      LAA  IL  S   S   R+ S++ + F+A  L+++ 
Sbjct: 148 SIRNFTETHVGSWQVPLLGHYPDFLAAGIILLASAFVSCGARVSSWLNHTFSAISLLVIL 207

Query: 190 IIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNYITEELRNPY 249
            I+I G +L    N    +  F  A      +     +  +A+ G++ +   +EE +NP 
Sbjct: 208 FIVILGFILAQPHNWSADEGGF--APFGFSGVMAGTASCFYAFVGFDVIAASSEEAQNPR 265

Query: 250 RNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFV 309
           R++PLAI I + +    YIL++     ++    L    A+A  F  R    A +IV    
Sbjct: 266 RSVPLAIAISLAIAAGAYILVSTVLTLMVPWHSLDPDSALADAFYQRGYRWAGFIV---- 321

Query: 310 AFSTIGAAN----GTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIY 365
           A  +I A N       F+  R++Y    +G   +V +++  R   P    + +G++    
Sbjct: 322 AAGSICAMNTVLLSLLFSLPRIVYAMAADGLFFQVFAHVHPRTQVPVAGTLAFGLLTAFL 381

Query: 366 IIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTR 400
            +  D+ SLV + S    L Y      +IV+RF +
Sbjct: 382 ALLLDLESLVQFLSLGTLLAYTFVATSIIVLRFQK 416


>gi|114326550 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 3 [Homo sapiens]
          Length = 619

 Score =  103 bits (256), Expect = 5e-22
 Identities = 100/468 (21%), Positives = 199/468 (42%), Gaps = 47/468 (10%)

Query: 24  TSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGVLAT-LGALC 82
           T L + L  +  +++ VG+ +G+G++V    V    +  GP ++I      L++ L  LC
Sbjct: 26  TRLARCLSTLDLVALGVGSTLGAGVYVLAGEVAK--DKAGPSIVICFLVAALSSVLAGLC 83

Query: 83  FAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLI--VIKPTSFAIICLSFSEYVCAPF 140
           +AE G  + +SG  Y Y     G + A+   W  ++  VI   S A    S  + +    
Sbjct: 84  YAEFGARVPRSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNLIGNH 143

Query: 141 Y-------VGCKPPQIVVKC---LAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAI 190
                   +    P ++ +     A   +L ++ + +L     + V  +FT   L+++  
Sbjct: 144 ISKTLQGSIALHVPHVLAEYPDFFALGLVLLLTGLLALGASESALVTKVFTGVNLLVLGF 203

Query: 191 IIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNG---------------------- 228
           ++ISG V   +G+  N+  + E  +L++  ++  +  G                      
Sbjct: 204 VMISGFV---KGDVHNWKLTEEDYELAMAELNDTYSLGPLGSGGFVPFGFEGILRGAATC 260

Query: 229 LWAYDGWNQLNYITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQA 288
            +A+ G++ +    EE +NP R++P+ I+I + +    Y  ++ +   +M   +L     
Sbjct: 261 FYAFVGFDCIATTGEEAQNPQRSIPMGIVISLSVCFLAYFAVSSALTLMMPYYQLQPESP 320

Query: 289 VAVTFGDRVLYPASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRR 348
           +   F      PA ++V +    +   +  G+ F   R+IY    +G + +VL+ I    
Sbjct: 321 LPEAFLYIGWAPARYVVAVGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFRVLARIHTGT 380

Query: 349 LTPAPAIIFYGIIATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRF-------TRK 401
            TP  A +  GIIA        +  LV+  S    L Y L  + ++++R+       T +
Sbjct: 381 RTPIIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLLAYSLVSICVLILRYQPDQETKTGE 440

Query: 402 ELERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEYLYCVLFILSGLL 449
           E+E   +        +TL  +F  L  I +  + + +Y    +L+ LL
Sbjct: 441 EVELQEEAITTESEKLTLWGLFFPLNSIPTPLSGQIVYVCSSLLAVLL 488


>gi|114326544 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 3 [Homo sapiens]
          Length = 619

 Score =  103 bits (256), Expect = 5e-22
 Identities = 100/468 (21%), Positives = 199/468 (42%), Gaps = 47/468 (10%)

Query: 24  TSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGVLAT-LGALC 82
           T L + L  +  +++ VG+ +G+G++V    V    +  GP ++I      L++ L  LC
Sbjct: 26  TRLARCLSTLDLVALGVGSTLGAGVYVLAGEVAK--DKAGPSIVICFLVAALSSVLAGLC 83

Query: 83  FAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLI--VIKPTSFAIICLSFSEYVCAPF 140
           +AE G  + +SG  Y Y     G + A+   W  ++  VI   S A    S  + +    
Sbjct: 84  YAEFGARVPRSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNLIGNH 143

Query: 141 Y-------VGCKPPQIVVKC---LAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAI 190
                   +    P ++ +     A   +L ++ + +L     + V  +FT   L+++  
Sbjct: 144 ISKTLQGSIALHVPHVLAEYPDFFALGLVLLLTGLLALGASESALVTKVFTGVNLLVLGF 203

Query: 191 IIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNG---------------------- 228
           ++ISG V   +G+  N+  + E  +L++  ++  +  G                      
Sbjct: 204 VMISGFV---KGDVHNWKLTEEDYELAMAELNDTYSLGPLGSGGFVPFGFEGILRGAATC 260

Query: 229 LWAYDGWNQLNYITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQA 288
            +A+ G++ +    EE +NP R++P+ I+I + +    Y  ++ +   +M   +L     
Sbjct: 261 FYAFVGFDCIATTGEEAQNPQRSIPMGIVISLSVCFLAYFAVSSALTLMMPYYQLQPESP 320

Query: 289 VAVTFGDRVLYPASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRR 348
           +   F      PA ++V +    +   +  G+ F   R+IY    +G + +VL+ I    
Sbjct: 321 LPEAFLYIGWAPARYVVAVGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFRVLARIHTGT 380

Query: 349 LTPAPAIIFYGIIATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRF-------TRK 401
            TP  A +  GIIA        +  LV+  S    L Y L  + ++++R+       T +
Sbjct: 381 RTPIIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLLAYSLVSICVLILRYQPDQETKTGE 440

Query: 402 ELERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEYLYCVLFILSGLL 449
           E+E   +        +TL  +F  L  I +  + + +Y    +L+ LL
Sbjct: 441 EVELQEEAITTESEKLTLWGLFFPLNSIPTPLSGQIVYVCSSLLAVLL 488


>gi|134304858 solute carrier family 7, member 2 isoform 2 [Homo
           sapiens]
          Length = 658

 Score =  102 bits (253), Expect = 1e-21
 Identities = 94/416 (22%), Positives = 183/416 (43%), Gaps = 50/416 (12%)

Query: 24  TSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGVLATLGA-LC 82
           T L + L  +  I++ VG+ +G+G++V    V       GP +++      LA++ A LC
Sbjct: 28  TKLCRCLSTMDLIALGVGSTLGAGVYVLAGEVAKADS--GPSIVVSFLIAALASVMAGLC 85

Query: 83  FAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLI--VIKPTSFA---------IICLS 131
           +AE G  + K+G  Y Y     G + A++  W  ++  VI  +S A         ++   
Sbjct: 86  YAEFGARVPKTGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDELLSKQ 145

Query: 132 FSEYVCAPF---YVG-CKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVI 187
             +++   F   Y G  + P     CL    IL ++ + S  V+  ++V  +FTA  +++
Sbjct: 146 IGQFLRTYFRMNYTGLAEYPDFFAVCL----ILLLAGLLSFGVKESAWVNKVFTAVNILV 201

Query: 188 VAIIIISGLVLLAQGNTKNFDNSFEGAQ-LSVGAISLAFYNG------------------ 228
           +  ++++G V   +GN  N+  S E  + +S  A      NG                  
Sbjct: 202 LLFVMVAGFV---KGNVANWKISEEFLKNISASAREPPSENGTSIYGAGGFMPYGFTGTL 258

Query: 229 ------LWAYDGWNQLNYITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATE 282
                  +A+ G++ +    EE+RNP + +P+ I+  + +    Y  ++ +   +M    
Sbjct: 259 AGAATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYL 318

Query: 283 LLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLS 342
           L +   + V F      PA ++V      +   +  G+ F   R+IY    +G + K L+
Sbjct: 319 LDEKSPLPVAFEYVGWGPAKYVVAAGSLCALSTSLLGSIFPMPRVIYAMAEDGLLFKCLA 378

Query: 343 YISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRF 398
            I+ +  TP  A +  G +A +     D+ +LV+  S    + Y L    ++++R+
Sbjct: 379 QINSKTKTPIIATLSSGAVAALMAFLFDLKALVDMMSIGTLMAYSLVAACVLILRY 434


>gi|4507047 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 1 [Homo sapiens]
          Length = 629

 Score =  100 bits (250), Expect = 2e-21
 Identities = 91/412 (22%), Positives = 181/412 (43%), Gaps = 42/412 (10%)

Query: 24  TSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGVLAT-LGALC 82
           T L + L     +++ VG+ +G+G++V   +V    E  GP ++I      LA+ L  LC
Sbjct: 26  TRLSRCLNTFDLVALGVGSTLGAGVYVLAGAVAR--ENAGPAIVISFLIAALASVLAGLC 83

Query: 83  FAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLI--VIKPTSFAII-CLSFSEYVCAP 139
           + E G  + K+G  Y Y     G + A++  W  ++  +I  +S A     +F E +  P
Sbjct: 84  YGEFGARVPKTGSAYLYSYVTVGELWAFITGWNLILSYIIGTSSVARAWSATFDELIGRP 143

Query: 140 F------YVGCKPPQIVVK---CLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAI 190
                  ++    P ++ +     A   IL ++ + +L V+  + V  IFT   ++++  
Sbjct: 144 IGEFSRTHMTLNAPGVLAENPDIFAVIIILILTGLLTLGVKESAMVNKIFTCINVLVLGF 203

Query: 191 IIISGLVLLAQGNTKNF----------------DNSFEGAQLSVGAISLAFYNGL----- 229
           I++SG V   +G+ KN+                +N  +  +  VG      ++G+     
Sbjct: 204 IMVSGFV---KGSVKNWQLTEEDFGNTSGRLCLNNDTKEGKPGVGGFMPFGFSGVLSGAA 260

Query: 230 ---WAYDGWNQLNYITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQS 286
              +A+ G++ +    EE++NP + +P+ I+  + +    Y  ++ +   +M    L  +
Sbjct: 261 TCFYAFVGFDCIATTGEEVKNPQKAIPVGIVASLLICFIAYFGVSAALTLMMPYFCLDNN 320

Query: 287 QAVAVTFGDRVLYPASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISV 346
             +   F       A + V +    +   +  G+ F   R+IY    +G + K L+ ++ 
Sbjct: 321 SPLPDAFKHVGWEGAKYAVAVGSLCALSASLLGSMFPMPRVIYAMAEDGLLFKFLANVND 380

Query: 347 RRLTPAPAIIFYGIIATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRF 398
           R  TP  A +  G +A +     D+  LV+  S    L Y L    ++V+R+
Sbjct: 381 RTKTPIIATLASGAVAAVMAFLFDLKDLVDLMSIGTLLAYSLVAACVLVLRY 432


>gi|109948288 solute carrier family 7, member 2 isoform 1 [Homo
           sapiens]
          Length = 697

 Score =  100 bits (248), Expect = 4e-21
 Identities = 92/416 (22%), Positives = 186/416 (44%), Gaps = 51/416 (12%)

Query: 24  TSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGVLATLGA-LC 82
           T L + L  +  I++ VG+ +G+G++V    V       GP +++      LA++ A LC
Sbjct: 68  TKLCRCLSTMDLIALGVGSTLGAGVYVLAGEVAKADS--GPSIVVSFLIAALASVMAGLC 125

Query: 83  FAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLI--VIKPTSFA---------IICLS 131
           +AE G  + K+G  Y Y     G + A++  W  ++  VI  +S A         ++   
Sbjct: 126 YAEFGARVPKTGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDELLSKQ 185

Query: 132 FSEYVCAPF---YVG-CKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVI 187
             +++   F   Y G  + P     CL    IL ++ + S  V+  ++V  +FTA  +++
Sbjct: 186 IGQFLRTYFRMNYTGLAEYPDFFAVCL----ILLLAGLLSFGVKESAWVNKVFTAVNILV 241

Query: 188 VAIIIISGLVLLAQGNTKNFDNSFEGAQ-LSVGAISLAFYNG------------------ 228
           +  ++++G V   +GN  N+  S E  + +S  A      NG                  
Sbjct: 242 LLFVMVAGFV---KGNVANWKISEEFLKNISASAREPPSENGTSIYGAGGFMPYGFTGTL 298

Query: 229 ------LWAYDGWNQLNYITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATE 282
                  +A+ G++ +    EE+RNP + +P+ I+  + +    Y  ++ +   +M    
Sbjct: 299 AGAATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYL 358

Query: 283 LLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLS 342
           L +   + V F      PA ++V      +   +  G+ F   R+++   R+G + + L+
Sbjct: 359 LDEKSPLPVAFEYVGWGPAKYVVAAGSLCALSTSLLGSMFPLPRILFAMARDGLLFRFLA 418

Query: 343 YISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRF 398
            +S +R +P  A +  G+I+ +     D+ +LV+  S    + Y L    ++++R+
Sbjct: 419 RVS-KRQSPVAATLTAGVISALMAFLFDLKALVDMMSIGTLMAYSLVAACVLILRY 473


>gi|181337167 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 14 [Homo sapiens]
          Length = 771

 Score = 85.9 bits (211), Expect = 8e-17
 Identities = 85/399 (21%), Positives = 166/399 (41%), Gaps = 38/399 (9%)

Query: 24  TSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLII-WAACGVLATLGALC 82
           T L + L  +  IS+ VG+ +G+G++V   S L   E  GP +I+ +    V + L  +C
Sbjct: 47  TKLAQVLTTVDLISLGVGSCVGTGMYVV--SGLVAKEMAGPGVIVSFIIAAVASILSGVC 104

Query: 83  FAELGTMITKS-GGEYPYLMEAYGPIPAYLFSWASLI------VIKPTSFAIICLSFSEY 135
           +AE G  + K+ G  Y Y     G   A+   W  ++          ++ + +  S + +
Sbjct: 105 YAEFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLILEYLIGTAAGASALSSMFDSLANH 164

Query: 136 VCAPFYVGC--------KPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVI 187
             + +            K  +     LA    + ++ + +L V+      N+     L +
Sbjct: 165 TISRWMADSVGTLNGLGKGEESYPDLLALLIAVIVTIIVALGVKNSIGFNNVLNVLNLAV 224

Query: 188 VAIIIISGLVLLAQGNTKNFDNSFEGAQLSVG--AISLAFYNGLWAYDGWNQLNYITEEL 245
              I+I+GL  +      N     EG  L  G   +        +A+ G++ +    EE 
Sbjct: 225 WVFIMIAGLFFI------NGKYWAEGQFLPHGWSGVLQGAATCFYAFIGFDIIATTGEEA 278

Query: 246 RNPYRNLPLAIIIGIPLVTACYILMNV------SYFTVMTATELLQSQAVAVTFGDRVLY 299
           +NP  ++P AI   + +    Y+ ++V       Y+T+ T + L++       F     Y
Sbjct: 279 KNPNTSIPYAITASLVICLTAYVSVSVILTLMVPYYTIDTESPLMEM------FVAHGFY 332

Query: 300 PASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYG 359
            A ++V +        +  G+ F   R+IY    +G + + L+++S    TP  A I  G
Sbjct: 333 AAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHVSSYTETPVVACIVSG 392

Query: 360 IIATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRF 398
            +A +  +   +  L+   S    L Y L  + ++++R+
Sbjct: 393 FLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRY 431


>gi|198041678 solute carrier family 12 (potassium-chloride
           transporter), member 5 isoform 1 [Homo sapiens]
          Length = 1139

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 50/216 (23%), Positives = 88/216 (40%), Gaps = 12/216 (5%)

Query: 244 ELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVL----Y 299
           +LR+  +++P   I+ I   +A YI   V +   +    L      AV  G+ V+    +
Sbjct: 446 DLRDAQKSIPTGTILAIATTSAVYISSVVLFGACIEGVVLRDKFGEAVN-GNLVVGTLAW 504

Query: 300 PASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREG--HMLKVLSYISVRRLTPAPAIIF 357
           P+ W++ +   FST GA   +   A RL+    R+G    L+V  +       P  A++ 
Sbjct: 505 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAISRDGIVPFLQVFGHGKANG-EPTWALLL 563

Query: 358 YGIIATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLM 417
              I  I I+   ++ +    S    + Y    L   V    R    RP        +  
Sbjct: 564 TACICEIGILIASLDEVAPILSMFFLMCYMFVNLACAVQTLLRTPNWRPRFRYYHWTLSF 623

Query: 418 TLISVFLVLAPIISKPTWEYLYCVLFILSGLLFYFL 453
             +S+ L L  I S   W Y   V  +++GL++ ++
Sbjct: 624 LGMSLCLALMFICS---W-YYALVAMLIAGLIYKYI 655


>gi|11968148 solute carrier family 12 (potassium-chloride
           transporter), member 5 isoform 2 [Homo sapiens]
          Length = 1116

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 50/216 (23%), Positives = 88/216 (40%), Gaps = 12/216 (5%)

Query: 244 ELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVL----Y 299
           +LR+  +++P   I+ I   +A YI   V +   +    L      AV  G+ V+    +
Sbjct: 423 DLRDAQKSIPTGTILAIATTSAVYISSVVLFGACIEGVVLRDKFGEAVN-GNLVVGTLAW 481

Query: 300 PASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREG--HMLKVLSYISVRRLTPAPAIIF 357
           P+ W++ +   FST GA   +   A RL+    R+G    L+V  +       P  A++ 
Sbjct: 482 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAISRDGIVPFLQVFGHGKANG-EPTWALLL 540

Query: 358 YGIIATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLM 417
              I  I I+   ++ +    S    + Y    L   V    R    RP        +  
Sbjct: 541 TACICEIGILIASLDEVAPILSMFFLMCYMFVNLACAVQTLLRTPNWRPRFRYYHWTLSF 600

Query: 418 TLISVFLVLAPIISKPTWEYLYCVLFILSGLLFYFL 453
             +S+ L L  I S   W Y   V  +++GL++ ++
Sbjct: 601 LGMSLCLALMFICS---W-YYALVAMLIAGLIYKYI 632


>gi|110224458 solute carrier family 12, member 6 isoform e [Homo
           sapiens]
          Length = 1135

 Score = 35.0 bits (79), Expect = 0.15
 Identities = 35/154 (22%), Positives = 70/154 (45%), Gaps = 11/154 (7%)

Query: 244 ELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVL----Y 299
           +L++  +++P+  I+ I L T+   L NV  F       +L+ +      G+ V+    +
Sbjct: 493 DLKDAQKSIPIGTILAI-LTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSW 551

Query: 300 PASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREG--HMLKVLSYISVRRLTPAPAIIF 357
           P+ W++ +   FST GA   +   A RL+    ++     L+V  + S     P  A++ 
Sbjct: 552 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGH-SKANGEPTWALLL 610

Query: 358 YGIIATIYIIPGDIN---SLVNYFSFAAWLFYGL 388
              IA + I+   ++    +++ F    +LF  L
Sbjct: 611 TAAIAELGILIASLDLVAPILSMFFLMCYLFVNL 644


>gi|110224456 solute carrier family 12, member 6 isoform d [Homo
           sapiens]
          Length = 1141

 Score = 35.0 bits (79), Expect = 0.15
 Identities = 35/154 (22%), Positives = 70/154 (45%), Gaps = 11/154 (7%)

Query: 244 ELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVL----Y 299
           +L++  +++P+  I+ I L T+   L NV  F       +L+ +      G+ V+    +
Sbjct: 499 DLKDAQKSIPIGTILAI-LTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSW 557

Query: 300 PASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREG--HMLKVLSYISVRRLTPAPAIIF 357
           P+ W++ +   FST GA   +   A RL+    ++     L+V  + S     P  A++ 
Sbjct: 558 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGH-SKANGEPTWALLL 616

Query: 358 YGIIATIYIIPGDIN---SLVNYFSFAAWLFYGL 388
              IA + I+   ++    +++ F    +LF  L
Sbjct: 617 TAAIAELGILIASLDLVAPILSMFFLMCYLFVNL 650


>gi|110224454 solute carrier family 12, member 6 isoform c [Homo
           sapiens]
          Length = 1091

 Score = 35.0 bits (79), Expect = 0.15
 Identities = 35/154 (22%), Positives = 70/154 (45%), Gaps = 11/154 (7%)

Query: 244 ELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVL----Y 299
           +L++  +++P+  I+ I L T+   L NV  F       +L+ +      G+ V+    +
Sbjct: 449 DLKDAQKSIPIGTILAI-LTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSW 507

Query: 300 PASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREG--HMLKVLSYISVRRLTPAPAIIF 357
           P+ W++ +   FST GA   +   A RL+    ++     L+V  + S     P  A++ 
Sbjct: 508 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGH-SKANGEPTWALLL 566

Query: 358 YGIIATIYIIPGDIN---SLVNYFSFAAWLFYGL 388
              IA + I+   ++    +++ F    +LF  L
Sbjct: 567 TAAIAELGILIASLDLVAPILSMFFLMCYLFVNL 600


>gi|110224452 solute carrier family 12, member 6 isoform c [Homo
           sapiens]
          Length = 1091

 Score = 35.0 bits (79), Expect = 0.15
 Identities = 35/154 (22%), Positives = 70/154 (45%), Gaps = 11/154 (7%)

Query: 244 ELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVL----Y 299
           +L++  +++P+  I+ I L T+   L NV  F       +L+ +      G+ V+    +
Sbjct: 449 DLKDAQKSIPIGTILAI-LTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSW 507

Query: 300 PASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREG--HMLKVLSYISVRRLTPAPAIIF 357
           P+ W++ +   FST GA   +   A RL+    ++     L+V  + S     P  A++ 
Sbjct: 508 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGH-SKANGEPTWALLL 566

Query: 358 YGIIATIYIIPGDIN---SLVNYFSFAAWLFYGL 388
              IA + I+   ++    +++ F    +LF  L
Sbjct: 567 TAAIAELGILIASLDLVAPILSMFFLMCYLFVNL 600


>gi|4826780 solute carrier family 12, member 6 isoform b [Homo
           sapiens]
          Length = 1099

 Score = 35.0 bits (79), Expect = 0.15
 Identities = 35/154 (22%), Positives = 70/154 (45%), Gaps = 11/154 (7%)

Query: 244 ELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVL----Y 299
           +L++  +++P+  I+ I L T+   L NV  F       +L+ +      G+ V+    +
Sbjct: 457 DLKDAQKSIPIGTILAI-LTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSW 515

Query: 300 PASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREG--HMLKVLSYISVRRLTPAPAIIF 357
           P+ W++ +   FST GA   +   A RL+    ++     L+V  + S     P  A++ 
Sbjct: 516 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGH-SKANGEPTWALLL 574

Query: 358 YGIIATIYIIPGDIN---SLVNYFSFAAWLFYGL 388
              IA + I+   ++    +++ F    +LF  L
Sbjct: 575 TAAIAELGILIASLDLVAPILSMFFLMCYLFVNL 608


>gi|110224449 solute carrier family 12, member 6 isoform a [Homo
           sapiens]
          Length = 1150

 Score = 35.0 bits (79), Expect = 0.15
 Identities = 35/154 (22%), Positives = 70/154 (45%), Gaps = 11/154 (7%)

Query: 244 ELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVL----Y 299
           +L++  +++P+  I+ I L T+   L NV  F       +L+ +      G+ V+    +
Sbjct: 508 DLKDAQKSIPIGTILAI-LTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSW 566

Query: 300 PASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREG--HMLKVLSYISVRRLTPAPAIIF 357
           P+ W++ +   FST GA   +   A RL+    ++     L+V  + S     P  A++ 
Sbjct: 567 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGH-SKANGEPTWALLL 625

Query: 358 YGIIATIYIIPGDIN---SLVNYFSFAAWLFYGL 388
              IA + I+   ++    +++ F    +LF  L
Sbjct: 626 TAAIAELGILIASLDLVAPILSMFFLMCYLFVNL 659


>gi|41327726 nicotinic acetylcholine receptor beta 1 subunit
           precursor [Homo sapiens]
          Length = 501

 Score = 33.5 bits (75), Expect = 0.45
 Identities = 26/109 (23%), Positives = 49/109 (44%), Gaps = 16/109 (14%)

Query: 332 GREGHMLKVLSYISVRRL-------TPAPAIIFYGIIATIYIIPGDINSLVNYFSFAAWL 384
           GREG   +V+ Y+ +RR          AP I+   +   ++ +P D    +    FA   
Sbjct: 227 GREGQRQEVIFYLIIRRKPLFYLVNVIAPCILITLLAIFVFYLPPDAGEKMGLSIFA--- 283

Query: 385 FYGLTILGLIVMRFTRKELERPIKVPVVIPVL---MTLISVFLVLAPII 430
              L  L + ++    K  E  + VP++I  L   M L++  ++L+ ++
Sbjct: 284 ---LLTLTVFLLLLADKVPETSLSVPIIIKYLMFTMVLVTFSVILSVVV 329


>gi|31881740 solute carrier family 12 (potassium/chloride
           transporters), member 9 [Homo sapiens]
          Length = 914

 Score = 33.5 bits (75), Expect = 0.45
 Identities = 36/186 (19%), Positives = 79/186 (42%), Gaps = 13/186 (6%)

Query: 213 GAQLSVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPLAIIIGIPLVTACYILMNV 272
           GA ++  ++    +NG         ++    EL++P R +PL  I+ +      Y+L+  
Sbjct: 262 GAVMNFASVFAVLFNGCTGIMAGANMS---GELKDPSRAIPLGTIVAVAYTFFVYVLL-- 316

Query: 273 SYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAANGTCFTAGRLIYVAG 332
            + +  T    L  +     F    L+P   ++ ++   + + A+  +   A R+++   
Sbjct: 317 FFLSSFTCDRTLLQEDYGF-FRAISLWPPLVLIGIYA--TALSASMSSLIGASRILHALA 373

Query: 333 REGHMLKVLSYISV--RRLTPAPAIIFYGIIATIYIIPGDINSL---VNYFSFAAWLFYG 387
           R+     +L+   V  R   P  A+++   +  + ++ G +N+L   V  F   A+    
Sbjct: 374 RDDLFGVILAPAKVVSRGGNPWAAVLYSWGLVQLVLLAGKLNTLAAVVTVFYLVAYAAVD 433

Query: 388 LTILGL 393
           L+ L L
Sbjct: 434 LSCLSL 439


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.142    0.431 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,322,131
Number of Sequences: 37866
Number of extensions: 706808
Number of successful extensions: 2211
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 2144
Number of HSP's gapped (non-prelim): 53
length of query: 487
length of database: 18,247,518
effective HSP length: 106
effective length of query: 381
effective length of database: 14,233,722
effective search space: 5423048082
effective search space used: 5423048082
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press