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Search of human proteins with 7657591
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7657591 solute carrier family 7, member 9 [Homo sapiens]
(487 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|187423910 solute carrier family 7, member 9 [Homo sapiens] 964 0.0
gi|7657591 solute carrier family 7, member 9 [Homo sapiens] 964 0.0
gi|7657683 solute carrier family 7, (cationic amino acid transpo... 419 e-117
gi|71979932 solute carrier family 7 (cationic amino acid transpo... 415 e-116
gi|115648063 solute carrier family 7 (cationic amino acid transp... 411 e-115
gi|115648022 solute carrier family 7 (cationic amino acid transp... 411 e-115
gi|186910308 solute carrier family 7 member 7 [Homo sapiens] 410 e-114
gi|186910306 solute carrier family 7 member 7 [Homo sapiens] 410 e-114
gi|186910304 solute carrier family 7 member 7 [Homo sapiens] 410 e-114
gi|33286428 solute carrier family 7 (cationic amino acid transpo... 387 e-107
gi|9790235 solute carrier family 7, member 10 [Homo sapiens] 369 e-102
gi|71999149 solute carrier family 7, (cationic amino acid transp... 254 1e-67
gi|33286430 solute carrier family 7 (cationic amino acid transpo... 222 7e-58
gi|110347453 solute carrier family 7 (cationic amino acid transp... 125 7e-29
gi|114326550 solute carrier family 7 (cationic amino acid transp... 103 5e-22
gi|114326544 solute carrier family 7 (cationic amino acid transp... 103 5e-22
gi|134304858 solute carrier family 7, member 2 isoform 2 [Homo s... 102 1e-21
gi|4507047 solute carrier family 7 (cationic amino acid transpor... 100 2e-21
gi|109948288 solute carrier family 7, member 2 isoform 1 [Homo s... 100 4e-21
gi|181337167 solute carrier family 7 (cationic amino acid transp... 86 8e-17
gi|198041678 solute carrier family 12 (potassium-chloride transp... 39 0.011
gi|11968148 solute carrier family 12 (potassium-chloride transpo... 39 0.011
gi|110224458 solute carrier family 12, member 6 isoform e [Homo ... 35 0.15
gi|110224456 solute carrier family 12, member 6 isoform d [Homo ... 35 0.15
gi|110224454 solute carrier family 12, member 6 isoform c [Homo ... 35 0.15
gi|110224452 solute carrier family 12, member 6 isoform c [Homo ... 35 0.15
gi|4826780 solute carrier family 12, member 6 isoform b [Homo sa... 35 0.15
gi|110224449 solute carrier family 12, member 6 isoform a [Homo ... 35 0.15
gi|41327726 nicotinic acetylcholine receptor beta 1 subunit prec... 33 0.45
gi|31881740 solute carrier family 12 (potassium/chloride transpo... 33 0.45
>gi|187423910 solute carrier family 7, member 9 [Homo sapiens]
Length = 487
Score = 964 bits (2491), Expect = 0.0
Identities = 487/487 (100%), Positives = 487/487 (100%)
Query: 1 MGDTGLRKRREDEKSIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTE 60
MGDTGLRKRREDEKSIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTE
Sbjct: 1 MGDTGLRKRREDEKSIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTE 60
Query: 61 AVGPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVI 120
AVGPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVI
Sbjct: 61 AVGPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVI 120
Query: 121 KPTSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIF 180
KPTSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIF
Sbjct: 121 KPTSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIF 180
Query: 181 TAAKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNY 240
TAAKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNY
Sbjct: 181 TAAKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNY 240
Query: 241 ITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYP 300
ITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYP
Sbjct: 241 ITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYP 300
Query: 301 ASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGI 360
ASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGI
Sbjct: 301 ASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGI 360
Query: 361 IATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLI 420
IATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLI
Sbjct: 361 IATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLI 420
Query: 421 SVFLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVHYKFGWAQKISKPITMHLQMLMEVV 480
SVFLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVHYKFGWAQKISKPITMHLQMLMEVV
Sbjct: 421 SVFLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVHYKFGWAQKISKPITMHLQMLMEVV 480
Query: 481 PPEEDPE 487
PPEEDPE
Sbjct: 481 PPEEDPE 487
>gi|7657591 solute carrier family 7, member 9 [Homo sapiens]
Length = 487
Score = 964 bits (2491), Expect = 0.0
Identities = 487/487 (100%), Positives = 487/487 (100%)
Query: 1 MGDTGLRKRREDEKSIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTE 60
MGDTGLRKRREDEKSIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTE
Sbjct: 1 MGDTGLRKRREDEKSIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTE 60
Query: 61 AVGPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVI 120
AVGPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVI
Sbjct: 61 AVGPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVI 120
Query: 121 KPTSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIF 180
KPTSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIF
Sbjct: 121 KPTSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIF 180
Query: 181 TAAKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNY 240
TAAKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNY
Sbjct: 181 TAAKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNY 240
Query: 241 ITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYP 300
ITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYP
Sbjct: 241 ITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYP 300
Query: 301 ASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGI 360
ASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGI
Sbjct: 301 ASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGI 360
Query: 361 IATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLI 420
IATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLI
Sbjct: 361 IATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLI 420
Query: 421 SVFLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVHYKFGWAQKISKPITMHLQMLMEVV 480
SVFLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVHYKFGWAQKISKPITMHLQMLMEVV
Sbjct: 421 SVFLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVHYKFGWAQKISKPITMHLQMLMEVV 480
Query: 481 PPEEDPE 487
PPEEDPE
Sbjct: 481 PPEEDPE 487
>gi|7657683 solute carrier family 7, (cationic amino acid
transporter, y+ system) member 11 [Homo sapiens]
Length = 501
Score = 419 bits (1076), Expect = e-117
Identities = 210/475 (44%), Positives = 312/475 (65%), Gaps = 6/475 (1%)
Query: 15 SIQSQEP---KTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAA 71
S+ ++EP + L++++ L+ G+SII+GTIIG+GIF+SPK VL NT +VG L IW
Sbjct: 26 SLGNKEPPGQEKVQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTGSVGMSLTIWTV 85
Query: 72 CGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLS 131
CGVL+ GAL +AELGT I KSGG Y Y++E +GP+PA++ W L++I+P + A+I L+
Sbjct: 86 CGVLSLFGALSYAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELLIIRPAATAVISLA 145
Query: 132 FSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAII 191
F Y+ PF++ C+ P++ +K + A I + +NS+SV + +Q T KL + II
Sbjct: 146 FGRYILEPFFIQCEIPELAIKLITAVGITVVMVLNSMSVSWSARIQIFLTFCKLTAILII 205
Query: 192 IISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRN 251
I+ G++ L +G T+NF ++F G S+ + LAFY G++AY GW LN++TEE+ NP +
Sbjct: 206 IVPGVMQLIKGQTQNFKDAFSGRDSSITRLPLAFYYGMYAYAGWFYLNFVTEEVENPEKT 265
Query: 252 LPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAF 311
+PLAI I + +VT Y+L NV+YFT + A ELL S AVAVTF +R+L S VP+FVA
Sbjct: 266 IPLAICISMAIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSERLLGNFSLAVPIFVAL 325
Query: 312 STIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDI 371
S G+ NG F RL YVA REGH+ ++LS I VR+ TP PA+I + I + GD+
Sbjct: 326 SCFGSMNGGVFAVSRLFYVASREGHLPEILSMIHVRKHTPLPAVIVLHPLTMIMLFSGDL 385
Query: 372 NSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIIS 431
+SL+N+ SFA WLF GL + GLI +R+ ++ RP KVP+ IP L + +F+V + S
Sbjct: 386 DSLLNFLSFARWLFIGLAVAGLIYLRYKCPDMHRPFKVPLFIPALFSFTCLFMVALSLYS 445
Query: 432 KPTWEYLYCVLFILSGLLFYFLFVHY--KFGWAQKISKPITMHLQMLMEVVPPEE 484
P + V+ L+G+ Y+LF+ + K W + +S+ IT LQ+++EVVP E+
Sbjct: 446 DPFSTGIGFVI-TLTGVPAYYLFIIWDKKPRWFRIMSEKITRTLQIILEVVPEED 499
>gi|71979932 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 5 [Homo sapiens]
Length = 507
Score = 415 bits (1066), Expect = e-116
Identities = 214/473 (45%), Positives = 306/473 (64%), Gaps = 5/473 (1%)
Query: 15 SIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGV 74
S + E + +LQ+ + L++G++IIVGTIIGSGIFV+P VL + G L++WAACGV
Sbjct: 35 SAPAGEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGV 94
Query: 75 LATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLSFSE 134
+ +GALC+AELGT I+KSGG+Y Y++E YG +PA+L W L++I+P+S I+ L F+
Sbjct: 95 FSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFAT 154
Query: 135 YVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAIIIIS 194
Y+ P + C P+ K +A +L ++ VN SV+ + VQ+ F AAKL+ +A+II+
Sbjct: 155 YLLKPLFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILL 214
Query: 195 GLVLLAQGNTKNFDN--SFEGAQLSVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNL 252
G V + +G+ N D SFEG +L VG I LA Y+GL+AY GWN LN++TEE+ NPYRNL
Sbjct: 215 GFVQIGKGDVSNLDPNFSFEGTKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNL 274
Query: 253 PLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFS 312
PLAIII +P+VT Y+L N++YFT ++ ++L S+AVAV FG+ L SWI+P+FV S
Sbjct: 275 PLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLS 334
Query: 313 TIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDIN 372
G+ NG+ FT+ RL +V REGH+ +LS I + LTP P+++F ++ +Y DI
Sbjct: 335 CFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIF 394
Query: 373 SLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIISK 432
S++N+FSF WL L I+G+I +R + ELERPIKV + +PV L +FL+
Sbjct: 395 SVINFFSFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVSFWKT 454
Query: 433 PTWEYLYCVLFILSGLLFYFLFVHYKF--GWAQKISKPITMHLQMLMEVVPPE 483
P E ILSGL YF V +K W + T+ Q LM+VVP E
Sbjct: 455 PV-ECGIGFTIILSGLPVYFFGVWWKNKPKWLLQGIFSTTVLCQKLMQVVPQE 506
>gi|115648063 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 6 [Homo sapiens]
Length = 515
Score = 411 bits (1057), Expect = e-115
Identities = 201/454 (44%), Positives = 303/454 (66%), Gaps = 1/454 (0%)
Query: 3 DTGLRKRREDEKSIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAV 62
+T + ED S + +T L+KE+ L++G+S++VG +IGSGIFVSPK VL +T +
Sbjct: 18 NTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASY 77
Query: 63 GPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKP 122
G LI+WA G+ + +GALC+AELGT ITKSG Y Y++EA+G A++ W SL+V++P
Sbjct: 78 GMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEP 137
Query: 123 TSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTA 182
T AII ++F+ Y+ P + C PP + + LAAA I ++ VN V+ G+ VQ+ FT
Sbjct: 138 TGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTFTY 197
Query: 183 AKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNYIT 242
AK+V + II+ GLV L QG++++F ++FEG+ +G +SLA Y+ L++Y GW+ LN++T
Sbjct: 198 AKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLALYSALFSYSGWDTLNFVT 257
Query: 243 EELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPAS 302
EE++NP RNLPLAI I +P+VT YIL NV+Y+TV+ +++L S AVAVTF D+ S
Sbjct: 258 EEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGMFS 317
Query: 303 WIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIA 362
W +P+ VA S G N + F + RL +V REGH+ +LS I + R TP PA++F +A
Sbjct: 318 WTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCTMA 377
Query: 363 TIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISV 422
IY+I D+ L+NYFSF+ W F GL+++G + +R+ + RP+K+ V P++ + SV
Sbjct: 378 LIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCICSV 437
Query: 423 FLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVH 456
FLV+ P+ + T L + LSG+ FYF+ V+
Sbjct: 438 FLVIVPLFT-DTINSLIGIGIALSGVPFYFMGVY 470
>gi|115648022 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 6 [Homo sapiens]
Length = 515
Score = 411 bits (1057), Expect = e-115
Identities = 201/454 (44%), Positives = 303/454 (66%), Gaps = 1/454 (0%)
Query: 3 DTGLRKRREDEKSIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAV 62
+T + ED S + +T L+KE+ L++G+S++VG +IGSGIFVSPK VL +T +
Sbjct: 18 NTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASY 77
Query: 63 GPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKP 122
G LI+WA G+ + +GALC+AELGT ITKSG Y Y++EA+G A++ W SL+V++P
Sbjct: 78 GMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEP 137
Query: 123 TSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTA 182
T AII ++F+ Y+ P + C PP + + LAAA I ++ VN V+ G+ VQ+ FT
Sbjct: 138 TGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTFTY 197
Query: 183 AKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNYIT 242
AK+V + II+ GLV L QG++++F ++FEG+ +G +SLA Y+ L++Y GW+ LN++T
Sbjct: 198 AKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLALYSALFSYSGWDTLNFVT 257
Query: 243 EELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPAS 302
EE++NP RNLPLAI I +P+VT YIL NV+Y+TV+ +++L S AVAVTF D+ S
Sbjct: 258 EEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGMFS 317
Query: 303 WIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIA 362
W +P+ VA S G N + F + RL +V REGH+ +LS I + R TP PA++F +A
Sbjct: 318 WTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCTMA 377
Query: 363 TIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISV 422
IY+I D+ L+NYFSF+ W F GL+++G + +R+ + RP+K+ V P++ + SV
Sbjct: 378 LIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCICSV 437
Query: 423 FLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVH 456
FLV+ P+ + T L + LSG+ FYF+ V+
Sbjct: 438 FLVIVPLFT-DTINSLIGIGIALSGVPFYFMGVY 470
>gi|186910308 solute carrier family 7 member 7 [Homo sapiens]
Length = 511
Score = 410 bits (1053), Expect = e-114
Identities = 208/474 (43%), Positives = 307/474 (64%), Gaps = 5/474 (1%)
Query: 18 SQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGVLAT 77
S P+ L+KE+ L++G+ +IVG +IGSGIFVSPK VL + + G L+IWA G+ +
Sbjct: 25 SPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVIWAVGGLFSV 84
Query: 78 LGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLSFSEYVC 137
GALC+AELGT I KSG Y Y++EA+G A++ W SL++I+PTS AII ++F+ Y+
Sbjct: 85 FGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLIIEPTSQAIIAITFANYMV 144
Query: 138 APFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAIIIISGLV 197
P + C P + LAAA I ++ +N V+ G+ VQ+IFT AK++ + +I++G+V
Sbjct: 145 QPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLALIAVIVAGIV 204
Query: 198 LLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPLAII 257
L QG + +F+NSFEG+ +VG I+LA Y+ L++Y GW+ LNY+TEE++NP RNLPL+I
Sbjct: 205 RLGQGASTHFENSFEGSSFAVGDIALALYSALFSYSGWDTLNYVTEEIKNPERNLPLSIG 264
Query: 258 IGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAA 317
I +P+VT YIL NV+Y+TV+ ++L S AVAVTF D++ +WI+PL VA S G
Sbjct: 265 ISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGIFNWIIPLSVALSCFGGL 324
Query: 318 NGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNY 377
N + A RL +V REGH+ + I V R TP P+++F GI+A IY+ DI L+NY
Sbjct: 325 NASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGIMALIYLCVEDIFQLINY 384
Query: 378 FSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEY 437
+SF+ W F GL+I+G + +R+ + RP+K+ V P++ L ++FLV P+ S T
Sbjct: 385 YSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFCLCTIFLVAVPLYS-DTINS 443
Query: 438 LYCVLFILSGLLFYFLFV----HYKFGWAQKISKPITMHLQMLMEVVPPEEDPE 487
L + LSGL FYFL + H + + ++I T +LQ+L V E D E
Sbjct: 444 LIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQVLCMSVAAEMDLE 497
>gi|186910306 solute carrier family 7 member 7 [Homo sapiens]
Length = 511
Score = 410 bits (1053), Expect = e-114
Identities = 208/474 (43%), Positives = 307/474 (64%), Gaps = 5/474 (1%)
Query: 18 SQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGVLAT 77
S P+ L+KE+ L++G+ +IVG +IGSGIFVSPK VL + + G L+IWA G+ +
Sbjct: 25 SPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVIWAVGGLFSV 84
Query: 78 LGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLSFSEYVC 137
GALC+AELGT I KSG Y Y++EA+G A++ W SL++I+PTS AII ++F+ Y+
Sbjct: 85 FGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLIIEPTSQAIIAITFANYMV 144
Query: 138 APFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAIIIISGLV 197
P + C P + LAAA I ++ +N V+ G+ VQ+IFT AK++ + +I++G+V
Sbjct: 145 QPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLALIAVIVAGIV 204
Query: 198 LLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPLAII 257
L QG + +F+NSFEG+ +VG I+LA Y+ L++Y GW+ LNY+TEE++NP RNLPL+I
Sbjct: 205 RLGQGASTHFENSFEGSSFAVGDIALALYSALFSYSGWDTLNYVTEEIKNPERNLPLSIG 264
Query: 258 IGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAA 317
I +P+VT YIL NV+Y+TV+ ++L S AVAVTF D++ +WI+PL VA S G
Sbjct: 265 ISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGIFNWIIPLSVALSCFGGL 324
Query: 318 NGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNY 377
N + A RL +V REGH+ + I V R TP P+++F GI+A IY+ DI L+NY
Sbjct: 325 NASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGIMALIYLCVEDIFQLINY 384
Query: 378 FSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEY 437
+SF+ W F GL+I+G + +R+ + RP+K+ V P++ L ++FLV P+ S T
Sbjct: 385 YSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFCLCTIFLVAVPLYS-DTINS 443
Query: 438 LYCVLFILSGLLFYFLFV----HYKFGWAQKISKPITMHLQMLMEVVPPEEDPE 487
L + LSGL FYFL + H + + ++I T +LQ+L V E D E
Sbjct: 444 LIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQVLCMSVAAEMDLE 497
>gi|186910304 solute carrier family 7 member 7 [Homo sapiens]
Length = 511
Score = 410 bits (1053), Expect = e-114
Identities = 208/474 (43%), Positives = 307/474 (64%), Gaps = 5/474 (1%)
Query: 18 SQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGVLAT 77
S P+ L+KE+ L++G+ +IVG +IGSGIFVSPK VL + + G L+IWA G+ +
Sbjct: 25 SPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVIWAVGGLFSV 84
Query: 78 LGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLSFSEYVC 137
GALC+AELGT I KSG Y Y++EA+G A++ W SL++I+PTS AII ++F+ Y+
Sbjct: 85 FGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLIIEPTSQAIIAITFANYMV 144
Query: 138 APFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAIIIISGLV 197
P + C P + LAAA I ++ +N V+ G+ VQ+IFT AK++ + +I++G+V
Sbjct: 145 QPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLALIAVIVAGIV 204
Query: 198 LLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPLAII 257
L QG + +F+NSFEG+ +VG I+LA Y+ L++Y GW+ LNY+TEE++NP RNLPL+I
Sbjct: 205 RLGQGASTHFENSFEGSSFAVGDIALALYSALFSYSGWDTLNYVTEEIKNPERNLPLSIG 264
Query: 258 IGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAA 317
I +P+VT YIL NV+Y+TV+ ++L S AVAVTF D++ +WI+PL VA S G
Sbjct: 265 ISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGIFNWIIPLSVALSCFGGL 324
Query: 318 NGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNY 377
N + A RL +V REGH+ + I V R TP P+++F GI+A IY+ DI L+NY
Sbjct: 325 NASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGIMALIYLCVEDIFQLINY 384
Query: 378 FSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEY 437
+SF+ W F GL+I+G + +R+ + RP+K+ V P++ L ++FLV P+ S T
Sbjct: 385 YSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFCLCTIFLVAVPLYS-DTINS 443
Query: 438 LYCVLFILSGLLFYFLFV----HYKFGWAQKISKPITMHLQMLMEVVPPEEDPE 487
L + LSGL FYFL + H + + ++I T +LQ+L V E D E
Sbjct: 444 LIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQVLCMSVAAEMDLE 497
>gi|33286428 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 8 isoform a [Homo
sapiens]
Length = 535
Score = 387 bits (993), Expect = e-107
Identities = 199/440 (45%), Positives = 292/440 (66%), Gaps = 10/440 (2%)
Query: 25 SLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGVLATLGALCFA 84
+L+KE+GL+S IIVG IIGSGIFVSPK VL N +VG LI+W G + +GALC+A
Sbjct: 35 ALKKEIGLVSACGIIVGNIIGSGIFVSPKGVLENAGSVGLALIVWIVTGFITVVGALCYA 94
Query: 85 ELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLSFSEYVCAPFYVGC 144
ELG I KSGG+Y Y+ + +G + +L W +++VI PT+ A+I L+FS YV P + C
Sbjct: 95 ELGVTIPKSGGDYSYVKDIFGGLAGFLRLWIAVLVIYPTNQAVIALTFSNYVLQPLFPTC 154
Query: 145 KPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAIIIISGLVLLAQGNT 204
PP+ ++ LAA +L ++ VN SVR + VQ+IFTA KL+ +A+III G+V + +G
Sbjct: 155 FPPESGLRLLAAICLLLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGIVQICKGEY 214
Query: 205 KNFD--NSFEGAQL-SVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPLAIIIGIP 261
+ N+FE Q +G ++LAF G +AY GWN LNY+TEEL +PY+NLP AI I IP
Sbjct: 215 FWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKNLPRAIFISIP 274
Query: 262 LVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAANGTC 321
LVT Y+ NV+Y T M+ ELL S AVAVTFG+++L +WI+P+ VA ST G NG+
Sbjct: 275 LVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVALSTFGGVNGSL 334
Query: 322 FTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNYFSFA 381
FT+ RL + REGH+ VL+ I V+R TP PA++F I + ++ D+ +L+NY F
Sbjct: 335 FTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDMYTLINYVGFI 394
Query: 382 AWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEYLYC- 440
+LFYG+T+ G IV+R+ + ++ RPIK+ ++ P++ L FL++ + S+P + C
Sbjct: 395 NYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLWSEP----VVCG 450
Query: 441 --VLFILSGLLFYFLFVHYK 458
+ +L+G+ YFL V+++
Sbjct: 451 IGLAIMLTGVPVYFLGVYWQ 470
>gi|9790235 solute carrier family 7, member 10 [Homo sapiens]
Length = 523
Score = 369 bits (946), Expect = e-102
Identities = 199/471 (42%), Positives = 300/471 (63%), Gaps = 12/471 (2%)
Query: 25 SLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGVLATLGALCFA 84
+L+KE+GL+S +II+G IIGSGIF+SPK VL ++ +VG L +W G + LG+LC+A
Sbjct: 35 ALKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHSGSVGLALFVWVLGGGVTALGSLCYA 94
Query: 85 ELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLSFSEYVCAPFYVGC 144
ELG I KSGG+Y Y+ E +G + +L W++++++ PTS A+I ++FS YV P + C
Sbjct: 95 ELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVISMTFSNYVLQPVFPNC 154
Query: 145 KPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAIIIISGLVLLAQGNT 204
PP + L+ A ++ ++ VNS SVR + +Q++FT KL+ +++II GL+ + QG+
Sbjct: 155 IPPTTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLIIGVGLLQIFQGHF 214
Query: 205 KNF--DNSFEGAQL-SVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPLAIIIGIP 261
+ N+F SVG ++LAF G +A+ GWN LNY+TEE+ + +NLP AI I IP
Sbjct: 215 EELRPSNAFAFWMTPSVGHLALAFLQGSFAFSGWNFLNYVTEEMVDARKNLPRAIFISIP 274
Query: 262 LVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAANGTC 321
LVT Y N++YFT M+ ELL S AVAVTFG+++L SW++P+ VA ST G NG
Sbjct: 275 LVTFVYTFTNIAYFTAMSPQELLSSNAVAVTFGEKLLGYFSWVMPVSVALSTFGGINGYL 334
Query: 322 FTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNYFSFA 381
FT RL + REGH+ +L+ I VR TP PA++ + ++ GD +L+NY SF
Sbjct: 335 FTYSRLCFSGAREGHLPSLLAMIHVRHCTPIPALLVCCGATAVIMLVGDTYTLINYVSFI 394
Query: 382 AWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEYLYC- 440
+L YG+TILGL+++R+ R L RPIKV ++IPV + FL++ IS+P + C
Sbjct: 395 NYLCYGVTILGLLLLRWRRPALHRPIKVNLLIPVAYLVFWAFLLVFSFISEP----MVCG 450
Query: 441 --VLFILSGLLFYFLFVHY--KFGWAQKISKPITMHLQMLMEVVPPEEDPE 487
V+ IL+G+ +FL V + K ++++ +T Q L VV P++ PE
Sbjct: 451 VGVIIILTGVPIFFLGVFWRSKPKCVHRLTESMTHWGQELCFVVYPQDAPE 501
>gi|71999149 solute carrier family 7, (cationic amino acid
transporter, y+ system) member 13 [Homo sapiens]
Length = 470
Score = 254 bits (649), Expect = 1e-67
Identities = 151/468 (32%), Positives = 246/468 (52%), Gaps = 12/468 (2%)
Query: 26 LQKELGLISGISIIVGTIIGSGIFVSPKSVLS-NTEAVGPCLIIWAACGVLATLGALCFA 84
L++ G G S ++ IIG+GIFVSPK VL+ + VG L +WA C +LA LC A
Sbjct: 9 LKRVFGYWWGTSFLLINIIGAGIFVSPKGVLAYSCMNVGVSLCVWAGCAILAMTSTLCSA 68
Query: 85 ELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLSFSEYVCAPFYVGC 144
E+ SG +Y +L +G A+L W SL + A L +EY PF+ C
Sbjct: 69 EISISFPCSGAQYYFLKRYFGSTVAFLNLWTSLFLGSGV-VAGQALLLAEYSIQPFFPSC 127
Query: 145 KPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAIIIISGLVLLAQG-- 202
P++ KCLA A + + + S V+ +++Q + K+ I++ I ++G+V L +G
Sbjct: 128 SVPKLPKKCLALAMLWIVGILTSRGVKEVTWLQIASSVLKVSILSFISLTGVVFLIRGKK 187
Query: 203 -NTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPLAIIIGIP 261
N + F N+F+ + + A + G +AY G I EL+ P +P I +P
Sbjct: 188 ENVERFQNAFDAELPDISHLIQAIFQGYFAYSGGACFTLIAGELKKPRTTIPKCIFTALP 247
Query: 262 LVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAANGTC 321
LVT Y+L+N+SY TV+T E+L S AVA+T+ DR +WI+P ++ S +
Sbjct: 248 LVTVVYLLVNISYLTVLTPREILSSDAVAITWADRAFPSLAWIMPFAISTSLFSNLLISI 307
Query: 322 FTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNYFSFA 381
F + R IY+A +EG + + + ++ +P A++ + ++ II + L+NY F
Sbjct: 308 FKSSRPIYLASQEGQLPLLFNTLN-SHSSPFTAVLLLVTLGSLAIILTSLIDLINYIFFT 366
Query: 382 AWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEYLYCV 441
L+ L ++G++ R+ L P KV + P+ +I V LV+ P++ P Y+Y +
Sbjct: 367 GSLWSILLMIGILRRRYQEPNLSIPYKVFLSFPLATIVIDVGLVVIPLVKSPNVHYVYVL 426
Query: 442 LFILSGLLFYFLFVHYK--FGWAQKISKPITMHLQMLMEVVPPEEDPE 487
L +LSGLLFY +H+K W +K +T +LQ+L + P+ E
Sbjct: 427 LLVLSGLLFYIPLIHFKIRLAWFEK----MTCYLQLLFNICLPDVSEE 470
>gi|33286430 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 8 isoform b [Homo
sapiens]
Length = 332
Score = 222 bits (565), Expect = 7e-58
Identities = 112/254 (44%), Positives = 168/254 (66%), Gaps = 8/254 (3%)
Query: 209 NSFEGAQL-SVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPLAIIIGIPLVTACY 267
N+FE Q +G ++LAF G +AY GWN LNY+TEEL +PY+NLP AI I IPLVT Y
Sbjct: 18 NAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVY 77
Query: 268 ILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAANGTCFTAGRL 327
+ NV+Y T M+ ELL S AVAVTFG+++L +WI+P+ VA ST G NG+ FT+ RL
Sbjct: 78 VFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVALSTFGGVNGSLFTSSRL 137
Query: 328 IYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNYFSFAAWLFYG 387
+ REGH+ VL+ I V+R TP PA++F I + ++ D+ +L+NY F +LFYG
Sbjct: 138 FFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDMYTLINYVGFINYLFYG 197
Query: 388 LTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEYLYC---VLFI 444
+T+ G IV+R+ + ++ RPIK+ ++ P++ L FL++ + S+P + C + +
Sbjct: 198 VTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLWSEP----VVCGIGLAIM 253
Query: 445 LSGLLFYFLFVHYK 458
L+G+ YFL V+++
Sbjct: 254 LTGVPVYFLGVYWQ 267
>gi|110347453 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 4 [Homo sapiens]
Length = 635
Score = 125 bits (315), Expect = 7e-29
Identities = 99/395 (25%), Positives = 182/395 (46%), Gaps = 27/395 (6%)
Query: 24 TSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLII-WAACGVLATLGALC 82
TSL++ L + + VG ++GSG++V +V E GP +++ + V + L ALC
Sbjct: 31 TSLRRCLSTLDLTLLGVGGMVGSGLYVLTGAVAK--EVAGPAVLLSFGVAAVASLLAALC 88
Query: 83 FAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLSFSEYVCAPF-- 140
+AE G + ++G Y + + G + A+L W ++++ A + ++S Y+ + F
Sbjct: 89 YAEFGARVPRTGSAYLFTYVSMGELWAFLIGW-NVLLEYIIGGAAVARAWSGYLDSMFSH 147
Query: 141 --------YVGCKPPQIV---VKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVA 189
+VG ++ LAA IL S S R+ S++ + F+A L+++
Sbjct: 148 SIRNFTETHVGSWQVPLLGHYPDFLAAGIILLASAFVSCGARVSSWLNHTFSAISLLVIL 207
Query: 190 IIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNYITEELRNPY 249
I+I G +L N + F A + + +A+ G++ + +EE +NP
Sbjct: 208 FIVILGFILAQPHNWSADEGGF--APFGFSGVMAGTASCFYAFVGFDVIAASSEEAQNPR 265
Query: 250 RNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFV 309
R++PLAI I + + YIL++ ++ L A+A F R A +IV
Sbjct: 266 RSVPLAIAISLAIAAGAYILVSTVLTLMVPWHSLDPDSALADAFYQRGYRWAGFIV---- 321
Query: 310 AFSTIGAAN----GTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIY 365
A +I A N F+ R++Y +G +V +++ R P + +G++
Sbjct: 322 AAGSICAMNTVLLSLLFSLPRIVYAMAADGLFFQVFAHVHPRTQVPVAGTLAFGLLTAFL 381
Query: 366 IIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTR 400
+ D+ SLV + S L Y +IV+RF +
Sbjct: 382 ALLLDLESLVQFLSLGTLLAYTFVATSIIVLRFQK 416
>gi|114326550 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 3 [Homo sapiens]
Length = 619
Score = 103 bits (256), Expect = 5e-22
Identities = 100/468 (21%), Positives = 199/468 (42%), Gaps = 47/468 (10%)
Query: 24 TSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGVLAT-LGALC 82
T L + L + +++ VG+ +G+G++V V + GP ++I L++ L LC
Sbjct: 26 TRLARCLSTLDLVALGVGSTLGAGVYVLAGEVAK--DKAGPSIVICFLVAALSSVLAGLC 83
Query: 83 FAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLI--VIKPTSFAIICLSFSEYVCAPF 140
+AE G + +SG Y Y G + A+ W ++ VI S A S + +
Sbjct: 84 YAEFGARVPRSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNLIGNH 143
Query: 141 Y-------VGCKPPQIVVKC---LAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAI 190
+ P ++ + A +L ++ + +L + V +FT L+++
Sbjct: 144 ISKTLQGSIALHVPHVLAEYPDFFALGLVLLLTGLLALGASESALVTKVFTGVNLLVLGF 203
Query: 191 IIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNG---------------------- 228
++ISG V +G+ N+ + E +L++ ++ + G
Sbjct: 204 VMISGFV---KGDVHNWKLTEEDYELAMAELNDTYSLGPLGSGGFVPFGFEGILRGAATC 260
Query: 229 LWAYDGWNQLNYITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQA 288
+A+ G++ + EE +NP R++P+ I+I + + Y ++ + +M +L
Sbjct: 261 FYAFVGFDCIATTGEEAQNPQRSIPMGIVISLSVCFLAYFAVSSALTLMMPYYQLQPESP 320
Query: 289 VAVTFGDRVLYPASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRR 348
+ F PA ++V + + + G+ F R+IY +G + +VL+ I
Sbjct: 321 LPEAFLYIGWAPARYVVAVGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFRVLARIHTGT 380
Query: 349 LTPAPAIIFYGIIATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRF-------TRK 401
TP A + GIIA + LV+ S L Y L + ++++R+ T +
Sbjct: 381 RTPIIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLLAYSLVSICVLILRYQPDQETKTGE 440
Query: 402 ELERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEYLYCVLFILSGLL 449
E+E + +TL +F L I + + + +Y +L+ LL
Sbjct: 441 EVELQEEAITTESEKLTLWGLFFPLNSIPTPLSGQIVYVCSSLLAVLL 488
>gi|114326544 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 3 [Homo sapiens]
Length = 619
Score = 103 bits (256), Expect = 5e-22
Identities = 100/468 (21%), Positives = 199/468 (42%), Gaps = 47/468 (10%)
Query: 24 TSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGVLAT-LGALC 82
T L + L + +++ VG+ +G+G++V V + GP ++I L++ L LC
Sbjct: 26 TRLARCLSTLDLVALGVGSTLGAGVYVLAGEVAK--DKAGPSIVICFLVAALSSVLAGLC 83
Query: 83 FAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLI--VIKPTSFAIICLSFSEYVCAPF 140
+AE G + +SG Y Y G + A+ W ++ VI S A S + +
Sbjct: 84 YAEFGARVPRSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNLIGNH 143
Query: 141 Y-------VGCKPPQIVVKC---LAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAI 190
+ P ++ + A +L ++ + +L + V +FT L+++
Sbjct: 144 ISKTLQGSIALHVPHVLAEYPDFFALGLVLLLTGLLALGASESALVTKVFTGVNLLVLGF 203
Query: 191 IIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNG---------------------- 228
++ISG V +G+ N+ + E +L++ ++ + G
Sbjct: 204 VMISGFV---KGDVHNWKLTEEDYELAMAELNDTYSLGPLGSGGFVPFGFEGILRGAATC 260
Query: 229 LWAYDGWNQLNYITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQA 288
+A+ G++ + EE +NP R++P+ I+I + + Y ++ + +M +L
Sbjct: 261 FYAFVGFDCIATTGEEAQNPQRSIPMGIVISLSVCFLAYFAVSSALTLMMPYYQLQPESP 320
Query: 289 VAVTFGDRVLYPASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRR 348
+ F PA ++V + + + G+ F R+IY +G + +VL+ I
Sbjct: 321 LPEAFLYIGWAPARYVVAVGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFRVLARIHTGT 380
Query: 349 LTPAPAIIFYGIIATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRF-------TRK 401
TP A + GIIA + LV+ S L Y L + ++++R+ T +
Sbjct: 381 RTPIIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLLAYSLVSICVLILRYQPDQETKTGE 440
Query: 402 ELERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEYLYCVLFILSGLL 449
E+E + +TL +F L I + + + +Y +L+ LL
Sbjct: 441 EVELQEEAITTESEKLTLWGLFFPLNSIPTPLSGQIVYVCSSLLAVLL 488
>gi|134304858 solute carrier family 7, member 2 isoform 2 [Homo
sapiens]
Length = 658
Score = 102 bits (253), Expect = 1e-21
Identities = 94/416 (22%), Positives = 183/416 (43%), Gaps = 50/416 (12%)
Query: 24 TSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGVLATLGA-LC 82
T L + L + I++ VG+ +G+G++V V GP +++ LA++ A LC
Sbjct: 28 TKLCRCLSTMDLIALGVGSTLGAGVYVLAGEVAKADS--GPSIVVSFLIAALASVMAGLC 85
Query: 83 FAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLI--VIKPTSFA---------IICLS 131
+AE G + K+G Y Y G + A++ W ++ VI +S A ++
Sbjct: 86 YAEFGARVPKTGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDELLSKQ 145
Query: 132 FSEYVCAPF---YVG-CKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVI 187
+++ F Y G + P CL IL ++ + S V+ ++V +FTA +++
Sbjct: 146 IGQFLRTYFRMNYTGLAEYPDFFAVCL----ILLLAGLLSFGVKESAWVNKVFTAVNILV 201
Query: 188 VAIIIISGLVLLAQGNTKNFDNSFEGAQ-LSVGAISLAFYNG------------------ 228
+ ++++G V +GN N+ S E + +S A NG
Sbjct: 202 LLFVMVAGFV---KGNVANWKISEEFLKNISASAREPPSENGTSIYGAGGFMPYGFTGTL 258
Query: 229 ------LWAYDGWNQLNYITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATE 282
+A+ G++ + EE+RNP + +P+ I+ + + Y ++ + +M
Sbjct: 259 AGAATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYL 318
Query: 283 LLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLS 342
L + + V F PA ++V + + G+ F R+IY +G + K L+
Sbjct: 319 LDEKSPLPVAFEYVGWGPAKYVVAAGSLCALSTSLLGSIFPMPRVIYAMAEDGLLFKCLA 378
Query: 343 YISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRF 398
I+ + TP A + G +A + D+ +LV+ S + Y L ++++R+
Sbjct: 379 QINSKTKTPIIATLSSGAVAALMAFLFDLKALVDMMSIGTLMAYSLVAACVLILRY 434
>gi|4507047 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 1 [Homo sapiens]
Length = 629
Score = 100 bits (250), Expect = 2e-21
Identities = 91/412 (22%), Positives = 181/412 (43%), Gaps = 42/412 (10%)
Query: 24 TSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGVLAT-LGALC 82
T L + L +++ VG+ +G+G++V +V E GP ++I LA+ L LC
Sbjct: 26 TRLSRCLNTFDLVALGVGSTLGAGVYVLAGAVAR--ENAGPAIVISFLIAALASVLAGLC 83
Query: 83 FAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLI--VIKPTSFAII-CLSFSEYVCAP 139
+ E G + K+G Y Y G + A++ W ++ +I +S A +F E + P
Sbjct: 84 YGEFGARVPKTGSAYLYSYVTVGELWAFITGWNLILSYIIGTSSVARAWSATFDELIGRP 143
Query: 140 F------YVGCKPPQIVVK---CLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAI 190
++ P ++ + A IL ++ + +L V+ + V IFT ++++
Sbjct: 144 IGEFSRTHMTLNAPGVLAENPDIFAVIIILILTGLLTLGVKESAMVNKIFTCINVLVLGF 203
Query: 191 IIISGLVLLAQGNTKNF----------------DNSFEGAQLSVGAISLAFYNGL----- 229
I++SG V +G+ KN+ +N + + VG ++G+
Sbjct: 204 IMVSGFV---KGSVKNWQLTEEDFGNTSGRLCLNNDTKEGKPGVGGFMPFGFSGVLSGAA 260
Query: 230 ---WAYDGWNQLNYITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQS 286
+A+ G++ + EE++NP + +P+ I+ + + Y ++ + +M L +
Sbjct: 261 TCFYAFVGFDCIATTGEEVKNPQKAIPVGIVASLLICFIAYFGVSAALTLMMPYFCLDNN 320
Query: 287 QAVAVTFGDRVLYPASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISV 346
+ F A + V + + + G+ F R+IY +G + K L+ ++
Sbjct: 321 SPLPDAFKHVGWEGAKYAVAVGSLCALSASLLGSMFPMPRVIYAMAEDGLLFKFLANVND 380
Query: 347 RRLTPAPAIIFYGIIATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRF 398
R TP A + G +A + D+ LV+ S L Y L ++V+R+
Sbjct: 381 RTKTPIIATLASGAVAAVMAFLFDLKDLVDLMSIGTLLAYSLVAACVLVLRY 432
>gi|109948288 solute carrier family 7, member 2 isoform 1 [Homo
sapiens]
Length = 697
Score = 100 bits (248), Expect = 4e-21
Identities = 92/416 (22%), Positives = 186/416 (44%), Gaps = 51/416 (12%)
Query: 24 TSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGVLATLGA-LC 82
T L + L + I++ VG+ +G+G++V V GP +++ LA++ A LC
Sbjct: 68 TKLCRCLSTMDLIALGVGSTLGAGVYVLAGEVAKADS--GPSIVVSFLIAALASVMAGLC 125
Query: 83 FAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLI--VIKPTSFA---------IICLS 131
+AE G + K+G Y Y G + A++ W ++ VI +S A ++
Sbjct: 126 YAEFGARVPKTGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDELLSKQ 185
Query: 132 FSEYVCAPF---YVG-CKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVI 187
+++ F Y G + P CL IL ++ + S V+ ++V +FTA +++
Sbjct: 186 IGQFLRTYFRMNYTGLAEYPDFFAVCL----ILLLAGLLSFGVKESAWVNKVFTAVNILV 241
Query: 188 VAIIIISGLVLLAQGNTKNFDNSFEGAQ-LSVGAISLAFYNG------------------ 228
+ ++++G V +GN N+ S E + +S A NG
Sbjct: 242 LLFVMVAGFV---KGNVANWKISEEFLKNISASAREPPSENGTSIYGAGGFMPYGFTGTL 298
Query: 229 ------LWAYDGWNQLNYITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATE 282
+A+ G++ + EE+RNP + +P+ I+ + + Y ++ + +M
Sbjct: 299 AGAATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYL 358
Query: 283 LLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLS 342
L + + V F PA ++V + + G+ F R+++ R+G + + L+
Sbjct: 359 LDEKSPLPVAFEYVGWGPAKYVVAAGSLCALSTSLLGSMFPLPRILFAMARDGLLFRFLA 418
Query: 343 YISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRF 398
+S +R +P A + G+I+ + D+ +LV+ S + Y L ++++R+
Sbjct: 419 RVS-KRQSPVAATLTAGVISALMAFLFDLKALVDMMSIGTLMAYSLVAACVLILRY 473
>gi|181337167 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 14 [Homo sapiens]
Length = 771
Score = 85.9 bits (211), Expect = 8e-17
Identities = 85/399 (21%), Positives = 166/399 (41%), Gaps = 38/399 (9%)
Query: 24 TSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLII-WAACGVLATLGALC 82
T L + L + IS+ VG+ +G+G++V S L E GP +I+ + V + L +C
Sbjct: 47 TKLAQVLTTVDLISLGVGSCVGTGMYVV--SGLVAKEMAGPGVIVSFIIAAVASILSGVC 104
Query: 83 FAELGTMITKS-GGEYPYLMEAYGPIPAYLFSWASLI------VIKPTSFAIICLSFSEY 135
+AE G + K+ G Y Y G A+ W ++ ++ + + S + +
Sbjct: 105 YAEFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLILEYLIGTAAGASALSSMFDSLANH 164
Query: 136 VCAPFYVGC--------KPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVI 187
+ + K + LA + ++ + +L V+ N+ L +
Sbjct: 165 TISRWMADSVGTLNGLGKGEESYPDLLALLIAVIVTIIVALGVKNSIGFNNVLNVLNLAV 224
Query: 188 VAIIIISGLVLLAQGNTKNFDNSFEGAQLSVG--AISLAFYNGLWAYDGWNQLNYITEEL 245
I+I+GL + N EG L G + +A+ G++ + EE
Sbjct: 225 WVFIMIAGLFFI------NGKYWAEGQFLPHGWSGVLQGAATCFYAFIGFDIIATTGEEA 278
Query: 246 RNPYRNLPLAIIIGIPLVTACYILMNV------SYFTVMTATELLQSQAVAVTFGDRVLY 299
+NP ++P AI + + Y+ ++V Y+T+ T + L++ F Y
Sbjct: 279 KNPNTSIPYAITASLVICLTAYVSVSVILTLMVPYYTIDTESPLMEM------FVAHGFY 332
Query: 300 PASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYG 359
A ++V + + G+ F R+IY +G + + L+++S TP A I G
Sbjct: 333 AAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHVSSYTETPVVACIVSG 392
Query: 360 IIATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRF 398
+A + + + L+ S L Y L + ++++R+
Sbjct: 393 FLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRY 431
>gi|198041678 solute carrier family 12 (potassium-chloride
transporter), member 5 isoform 1 [Homo sapiens]
Length = 1139
Score = 38.9 bits (89), Expect = 0.011
Identities = 50/216 (23%), Positives = 88/216 (40%), Gaps = 12/216 (5%)
Query: 244 ELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVL----Y 299
+LR+ +++P I+ I +A YI V + + L AV G+ V+ +
Sbjct: 446 DLRDAQKSIPTGTILAIATTSAVYISSVVLFGACIEGVVLRDKFGEAVN-GNLVVGTLAW 504
Query: 300 PASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREG--HMLKVLSYISVRRLTPAPAIIF 357
P+ W++ + FST GA + A RL+ R+G L+V + P A++
Sbjct: 505 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAISRDGIVPFLQVFGHGKANG-EPTWALLL 563
Query: 358 YGIIATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLM 417
I I I+ ++ + S + Y L V R RP +
Sbjct: 564 TACICEIGILIASLDEVAPILSMFFLMCYMFVNLACAVQTLLRTPNWRPRFRYYHWTLSF 623
Query: 418 TLISVFLVLAPIISKPTWEYLYCVLFILSGLLFYFL 453
+S+ L L I S W Y V +++GL++ ++
Sbjct: 624 LGMSLCLALMFICS---W-YYALVAMLIAGLIYKYI 655
>gi|11968148 solute carrier family 12 (potassium-chloride
transporter), member 5 isoform 2 [Homo sapiens]
Length = 1116
Score = 38.9 bits (89), Expect = 0.011
Identities = 50/216 (23%), Positives = 88/216 (40%), Gaps = 12/216 (5%)
Query: 244 ELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVL----Y 299
+LR+ +++P I+ I +A YI V + + L AV G+ V+ +
Sbjct: 423 DLRDAQKSIPTGTILAIATTSAVYISSVVLFGACIEGVVLRDKFGEAVN-GNLVVGTLAW 481
Query: 300 PASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREG--HMLKVLSYISVRRLTPAPAIIF 357
P+ W++ + FST GA + A RL+ R+G L+V + P A++
Sbjct: 482 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAISRDGIVPFLQVFGHGKANG-EPTWALLL 540
Query: 358 YGIIATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLM 417
I I I+ ++ + S + Y L V R RP +
Sbjct: 541 TACICEIGILIASLDEVAPILSMFFLMCYMFVNLACAVQTLLRTPNWRPRFRYYHWTLSF 600
Query: 418 TLISVFLVLAPIISKPTWEYLYCVLFILSGLLFYFL 453
+S+ L L I S W Y V +++GL++ ++
Sbjct: 601 LGMSLCLALMFICS---W-YYALVAMLIAGLIYKYI 632
>gi|110224458 solute carrier family 12, member 6 isoform e [Homo
sapiens]
Length = 1135
Score = 35.0 bits (79), Expect = 0.15
Identities = 35/154 (22%), Positives = 70/154 (45%), Gaps = 11/154 (7%)
Query: 244 ELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVL----Y 299
+L++ +++P+ I+ I L T+ L NV F +L+ + G+ V+ +
Sbjct: 493 DLKDAQKSIPIGTILAI-LTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSW 551
Query: 300 PASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREG--HMLKVLSYISVRRLTPAPAIIF 357
P+ W++ + FST GA + A RL+ ++ L+V + S P A++
Sbjct: 552 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGH-SKANGEPTWALLL 610
Query: 358 YGIIATIYIIPGDIN---SLVNYFSFAAWLFYGL 388
IA + I+ ++ +++ F +LF L
Sbjct: 611 TAAIAELGILIASLDLVAPILSMFFLMCYLFVNL 644
>gi|110224456 solute carrier family 12, member 6 isoform d [Homo
sapiens]
Length = 1141
Score = 35.0 bits (79), Expect = 0.15
Identities = 35/154 (22%), Positives = 70/154 (45%), Gaps = 11/154 (7%)
Query: 244 ELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVL----Y 299
+L++ +++P+ I+ I L T+ L NV F +L+ + G+ V+ +
Sbjct: 499 DLKDAQKSIPIGTILAI-LTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSW 557
Query: 300 PASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREG--HMLKVLSYISVRRLTPAPAIIF 357
P+ W++ + FST GA + A RL+ ++ L+V + S P A++
Sbjct: 558 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGH-SKANGEPTWALLL 616
Query: 358 YGIIATIYIIPGDIN---SLVNYFSFAAWLFYGL 388
IA + I+ ++ +++ F +LF L
Sbjct: 617 TAAIAELGILIASLDLVAPILSMFFLMCYLFVNL 650
>gi|110224454 solute carrier family 12, member 6 isoform c [Homo
sapiens]
Length = 1091
Score = 35.0 bits (79), Expect = 0.15
Identities = 35/154 (22%), Positives = 70/154 (45%), Gaps = 11/154 (7%)
Query: 244 ELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVL----Y 299
+L++ +++P+ I+ I L T+ L NV F +L+ + G+ V+ +
Sbjct: 449 DLKDAQKSIPIGTILAI-LTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSW 507
Query: 300 PASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREG--HMLKVLSYISVRRLTPAPAIIF 357
P+ W++ + FST GA + A RL+ ++ L+V + S P A++
Sbjct: 508 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGH-SKANGEPTWALLL 566
Query: 358 YGIIATIYIIPGDIN---SLVNYFSFAAWLFYGL 388
IA + I+ ++ +++ F +LF L
Sbjct: 567 TAAIAELGILIASLDLVAPILSMFFLMCYLFVNL 600
>gi|110224452 solute carrier family 12, member 6 isoform c [Homo
sapiens]
Length = 1091
Score = 35.0 bits (79), Expect = 0.15
Identities = 35/154 (22%), Positives = 70/154 (45%), Gaps = 11/154 (7%)
Query: 244 ELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVL----Y 299
+L++ +++P+ I+ I L T+ L NV F +L+ + G+ V+ +
Sbjct: 449 DLKDAQKSIPIGTILAI-LTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSW 507
Query: 300 PASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREG--HMLKVLSYISVRRLTPAPAIIF 357
P+ W++ + FST GA + A RL+ ++ L+V + S P A++
Sbjct: 508 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGH-SKANGEPTWALLL 566
Query: 358 YGIIATIYIIPGDIN---SLVNYFSFAAWLFYGL 388
IA + I+ ++ +++ F +LF L
Sbjct: 567 TAAIAELGILIASLDLVAPILSMFFLMCYLFVNL 600
>gi|4826780 solute carrier family 12, member 6 isoform b [Homo
sapiens]
Length = 1099
Score = 35.0 bits (79), Expect = 0.15
Identities = 35/154 (22%), Positives = 70/154 (45%), Gaps = 11/154 (7%)
Query: 244 ELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVL----Y 299
+L++ +++P+ I+ I L T+ L NV F +L+ + G+ V+ +
Sbjct: 457 DLKDAQKSIPIGTILAI-LTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSW 515
Query: 300 PASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREG--HMLKVLSYISVRRLTPAPAIIF 357
P+ W++ + FST GA + A RL+ ++ L+V + S P A++
Sbjct: 516 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGH-SKANGEPTWALLL 574
Query: 358 YGIIATIYIIPGDIN---SLVNYFSFAAWLFYGL 388
IA + I+ ++ +++ F +LF L
Sbjct: 575 TAAIAELGILIASLDLVAPILSMFFLMCYLFVNL 608
>gi|110224449 solute carrier family 12, member 6 isoform a [Homo
sapiens]
Length = 1150
Score = 35.0 bits (79), Expect = 0.15
Identities = 35/154 (22%), Positives = 70/154 (45%), Gaps = 11/154 (7%)
Query: 244 ELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVL----Y 299
+L++ +++P+ I+ I L T+ L NV F +L+ + G+ V+ +
Sbjct: 508 DLKDAQKSIPIGTILAI-LTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSW 566
Query: 300 PASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREG--HMLKVLSYISVRRLTPAPAIIF 357
P+ W++ + FST GA + A RL+ ++ L+V + S P A++
Sbjct: 567 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGH-SKANGEPTWALLL 625
Query: 358 YGIIATIYIIPGDIN---SLVNYFSFAAWLFYGL 388
IA + I+ ++ +++ F +LF L
Sbjct: 626 TAAIAELGILIASLDLVAPILSMFFLMCYLFVNL 659
>gi|41327726 nicotinic acetylcholine receptor beta 1 subunit
precursor [Homo sapiens]
Length = 501
Score = 33.5 bits (75), Expect = 0.45
Identities = 26/109 (23%), Positives = 49/109 (44%), Gaps = 16/109 (14%)
Query: 332 GREGHMLKVLSYISVRRL-------TPAPAIIFYGIIATIYIIPGDINSLVNYFSFAAWL 384
GREG +V+ Y+ +RR AP I+ + ++ +P D + FA
Sbjct: 227 GREGQRQEVIFYLIIRRKPLFYLVNVIAPCILITLLAIFVFYLPPDAGEKMGLSIFA--- 283
Query: 385 FYGLTILGLIVMRFTRKELERPIKVPVVIPVL---MTLISVFLVLAPII 430
L L + ++ K E + VP++I L M L++ ++L+ ++
Sbjct: 284 ---LLTLTVFLLLLADKVPETSLSVPIIIKYLMFTMVLVTFSVILSVVV 329
>gi|31881740 solute carrier family 12 (potassium/chloride
transporters), member 9 [Homo sapiens]
Length = 914
Score = 33.5 bits (75), Expect = 0.45
Identities = 36/186 (19%), Positives = 79/186 (42%), Gaps = 13/186 (6%)
Query: 213 GAQLSVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPLAIIIGIPLVTACYILMNV 272
GA ++ ++ +NG ++ EL++P R +PL I+ + Y+L+
Sbjct: 262 GAVMNFASVFAVLFNGCTGIMAGANMS---GELKDPSRAIPLGTIVAVAYTFFVYVLL-- 316
Query: 273 SYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAANGTCFTAGRLIYVAG 332
+ + T L + F L+P ++ ++ + + A+ + A R+++
Sbjct: 317 FFLSSFTCDRTLLQEDYGF-FRAISLWPPLVLIGIYA--TALSASMSSLIGASRILHALA 373
Query: 333 REGHMLKVLSYISV--RRLTPAPAIIFYGIIATIYIIPGDINSL---VNYFSFAAWLFYG 387
R+ +L+ V R P A+++ + + ++ G +N+L V F A+
Sbjct: 374 RDDLFGVILAPAKVVSRGGNPWAAVLYSWGLVQLVLLAGKLNTLAAVVTVFYLVAYAAVD 433
Query: 388 LTILGL 393
L+ L L
Sbjct: 434 LSCLSL 439
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.142 0.431
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,322,131
Number of Sequences: 37866
Number of extensions: 706808
Number of successful extensions: 2211
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 2144
Number of HSP's gapped (non-prelim): 53
length of query: 487
length of database: 18,247,518
effective HSP length: 106
effective length of query: 381
effective length of database: 14,233,722
effective search space: 5423048082
effective search space used: 5423048082
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.