Guide to the Human Genome
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Search of human proteins with 7657581

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo
sapiens]
         (675 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo s...  1337   0.0  
gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo...  1332   0.0  
gi|21361103 solute carrier family 25, member 12 [Homo sapiens]       1053   0.0  
gi|13375983 mitochondrial glutamate carrier 1 [Homo sapiens]          213   6e-55
gi|13899342 solute carrier [Homo sapiens]                             205   1e-52
gi|116235462 solute carrier family 25, member 45 isoform a [Homo...   126   7e-29
gi|13449279 solute carrier family 25 (mitochondrial oxodicarboxy...   122   8e-28
gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens]         119   9e-27
gi|13775208 solute carrier family 25 (mitochondrial carrier; ade...   117   5e-26
gi|46397377 chromosome 14 open reading frame 68 [Homo sapiens]        115   1e-25
gi|86198310 solute carrier family 25, member 29 [Homo sapiens]        113   7e-25
gi|55749577 solute carrier family 25 (mitochondrial carrier; ade...   110   6e-24
gi|157388989 solute carrier family 25, member 36 isoform a [Homo...   107   3e-23
gi|156071462 solute carrier family 25, member A6 [Homo sapiens]       107   4e-23
gi|45237193 solute carrier family 25, member 44 isoform 1 [Homo ...   104   2e-22
gi|116235466 solute carrier family 25, member 45 isoform b [Homo...   103   7e-22
gi|157388991 solute carrier family 25, member 36 isoform b [Homo...   102   9e-22
gi|82775373 solute carrier family 25, member 37 [Homo sapiens]        102   2e-21
gi|156071459 solute carrier family 25, member 5 [Homo sapiens]        101   3e-21
gi|7657585 mitochondrial ornithine transporter 1 [Homo sapiens]       100   6e-21
gi|13994341 solute carrier family 25 member 2 [Homo sapiens]          100   6e-21
gi|14150082 mitochondrial carrier protein MGC4399 [Homo sapiens]      100   6e-21
gi|115430257 solute carrier family 25, member 26 [Homo sapiens]        99   1e-20
gi|21389315 solute carrier family 25 (mitochondrial carrier; cit...    99   2e-20
gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Ho...    99   2e-20
gi|13259543 solute carrier family 25, member 14 isoform UCP5S [H...    99   2e-20
gi|149274643 solute carrier family 25, member 28 [Homo sapiens]        98   3e-20
gi|7706306 solute carrier family 25, member 39 isoform b [Homo s...    97   6e-20
gi|219555665 solute carrier family 25, member 39 isoform a [Homo...    97   6e-20
gi|27544933 solute carrier family 25, member 16 [Homo sapiens]         96   8e-20

>gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo
           sapiens]
          Length = 675

 Score = 1337 bits (3459), Expect = 0.0
 Identities = 675/675 (100%), Positives = 675/675 (100%)

Query: 1   MAAAKVALTKRADPAELRTIFLKYASIEKNGEFFMSPNDFVTRYLNIFGESQPNPKTVEL 60
           MAAAKVALTKRADPAELRTIFLKYASIEKNGEFFMSPNDFVTRYLNIFGESQPNPKTVEL
Sbjct: 1   MAAAKVALTKRADPAELRTIFLKYASIEKNGEFFMSPNDFVTRYLNIFGESQPNPKTVEL 60

Query: 61  LSGVVDQTKDGLISFQEFVAFESVLCAPDALFMVAFQLFDKAGKGEVTFEDVKQVFGQTT 120
           LSGVVDQTKDGLISFQEFVAFESVLCAPDALFMVAFQLFDKAGKGEVTFEDVKQVFGQTT
Sbjct: 61  LSGVVDQTKDGLISFQEFVAFESVLCAPDALFMVAFQLFDKAGKGEVTFEDVKQVFGQTT 120

Query: 121 IHQHIPFNWDSEFVQLHFGKERKRHLTYAEFTQFLLEIQLEHAKQAFVQRDNARTGRVTA 180
           IHQHIPFNWDSEFVQLHFGKERKRHLTYAEFTQFLLEIQLEHAKQAFVQRDNARTGRVTA
Sbjct: 121 IHQHIPFNWDSEFVQLHFGKERKRHLTYAEFTQFLLEIQLEHAKQAFVQRDNARTGRVTA 180

Query: 181 IDFRDIMVTIRPHVLTPFVEECLVAAAGGTTSHQVSFSYFNGFNSLLNNMELIRKIYSTL 240
           IDFRDIMVTIRPHVLTPFVEECLVAAAGGTTSHQVSFSYFNGFNSLLNNMELIRKIYSTL
Sbjct: 181 IDFRDIMVTIRPHVLTPFVEECLVAAAGGTTSHQVSFSYFNGFNSLLNNMELIRKIYSTL 240

Query: 241 AGTRKDVEVTKEEFVLAAQKFGQVTPMEVDILFQLADLYEPRGRMTLADIERIAPLEEGT 300
           AGTRKDVEVTKEEFVLAAQKFGQVTPMEVDILFQLADLYEPRGRMTLADIERIAPLEEGT
Sbjct: 241 AGTRKDVEVTKEEFVLAAQKFGQVTPMEVDILFQLADLYEPRGRMTLADIERIAPLEEGT 300

Query: 301 LPFNLAEAQRQKASGDSARPVLLQVAESAYRFGLGSVAGAVGATAVYPIDLVKTRMQNQR 360
           LPFNLAEAQRQKASGDSARPVLLQVAESAYRFGLGSVAGAVGATAVYPIDLVKTRMQNQR
Sbjct: 301 LPFNLAEAQRQKASGDSARPVLLQVAESAYRFGLGSVAGAVGATAVYPIDLVKTRMQNQR 360

Query: 361 STGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFM 420
           STGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFM
Sbjct: 361 STGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFM 420

Query: 421 HKDGSVPLAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFF 480
           HKDGSVPLAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFF
Sbjct: 421 HKDGSVPLAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFF 480

Query: 481 GIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTP 540
           GIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTP
Sbjct: 481 GIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTP 540

Query: 541 ADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTY 600
           ADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTY
Sbjct: 541 ADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTY 600

Query: 601 ELLQRWFYIDFGGVKPMGSEPVPKSRINLPAPNPDHVGGYKLAVATFAGIENKFGLYLPL 660
           ELLQRWFYIDFGGVKPMGSEPVPKSRINLPAPNPDHVGGYKLAVATFAGIENKFGLYLPL
Sbjct: 601 ELLQRWFYIDFGGVKPMGSEPVPKSRINLPAPNPDHVGGYKLAVATFAGIENKFGLYLPL 660

Query: 661 FKPSVSTSKAIGGGP 675
           FKPSVSTSKAIGGGP
Sbjct: 661 FKPSVSTSKAIGGGP 675


>gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo
           sapiens]
          Length = 676

 Score = 1332 bits (3447), Expect = 0.0
 Identities = 675/676 (99%), Positives = 675/676 (99%), Gaps = 1/676 (0%)

Query: 1   MAAAKVALTKRADPAELRTIFLKYASIEKNGEFFMSPNDFVTRYLNIFGESQPNPKTVEL 60
           MAAAKVALTKRADPAELRTIFLKYASIEKNGEFFMSPNDFVTRYLNIFGESQPNPKTVEL
Sbjct: 1   MAAAKVALTKRADPAELRTIFLKYASIEKNGEFFMSPNDFVTRYLNIFGESQPNPKTVEL 60

Query: 61  LSGVVDQTKDGLISFQEFVAFESVLCAPDALFMVAFQLFDKAGKGEVTFEDVKQVFGQTT 120
           LSGVVDQTKDGLISFQEFVAFESVLCAPDALFMVAFQLFDKAGKGEVTFEDVKQVFGQTT
Sbjct: 61  LSGVVDQTKDGLISFQEFVAFESVLCAPDALFMVAFQLFDKAGKGEVTFEDVKQVFGQTT 120

Query: 121 IHQHIPFNWDSEFVQLHFGKERKRHLTYAEFTQFLLEIQLEHAKQAFVQRDNARTGRVTA 180
           IHQHIPFNWDSEFVQLHFGKERKRHLTYAEFTQFLLEIQLEHAKQAFVQRDNARTGRVTA
Sbjct: 121 IHQHIPFNWDSEFVQLHFGKERKRHLTYAEFTQFLLEIQLEHAKQAFVQRDNARTGRVTA 180

Query: 181 IDFRDIMVTIRPHVLTPFVEECLVAAAGGTTSHQVSFSYFNGFNSLLNNMELIRKIYSTL 240
           IDFRDIMVTIRPHVLTPFVEECLVAAAGGTTSHQVSFSYFNGFNSLLNNMELIRKIYSTL
Sbjct: 181 IDFRDIMVTIRPHVLTPFVEECLVAAAGGTTSHQVSFSYFNGFNSLLNNMELIRKIYSTL 240

Query: 241 AGTRKDVEVTKEEFVLAAQKFGQVTPMEVDILFQLADLYEPRGRMTLADIERIAPLEEGT 300
           AGTRKDVEVTKEEFVLAAQKFGQVTPMEVDILFQLADLYEPRGRMTLADIERIAPLEEGT
Sbjct: 241 AGTRKDVEVTKEEFVLAAQKFGQVTPMEVDILFQLADLYEPRGRMTLADIERIAPLEEGT 300

Query: 301 LPFNLAEAQRQ-KASGDSARPVLLQVAESAYRFGLGSVAGAVGATAVYPIDLVKTRMQNQ 359
           LPFNLAEAQRQ KASGDSARPVLLQVAESAYRFGLGSVAGAVGATAVYPIDLVKTRMQNQ
Sbjct: 301 LPFNLAEAQRQQKASGDSARPVLLQVAESAYRFGLGSVAGAVGATAVYPIDLVKTRMQNQ 360

Query: 360 RSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKF 419
           RSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKF
Sbjct: 361 RSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKF 420

Query: 420 MHKDGSVPLAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGF 479
           MHKDGSVPLAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGF
Sbjct: 421 MHKDGSVPLAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGF 480

Query: 480 FGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVT 539
           FGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVT
Sbjct: 481 FGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVT 540

Query: 540 PADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLT 599
           PADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLT
Sbjct: 541 PADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLT 600

Query: 600 YELLQRWFYIDFGGVKPMGSEPVPKSRINLPAPNPDHVGGYKLAVATFAGIENKFGLYLP 659
           YELLQRWFYIDFGGVKPMGSEPVPKSRINLPAPNPDHVGGYKLAVATFAGIENKFGLYLP
Sbjct: 601 YELLQRWFYIDFGGVKPMGSEPVPKSRINLPAPNPDHVGGYKLAVATFAGIENKFGLYLP 660

Query: 660 LFKPSVSTSKAIGGGP 675
           LFKPSVSTSKAIGGGP
Sbjct: 661 LFKPSVSTSKAIGGGP 676


>gi|21361103 solute carrier family 25, member 12 [Homo sapiens]
          Length = 678

 Score = 1053 bits (2723), Expect = 0.0
 Identities = 521/666 (78%), Positives = 586/666 (87%), Gaps = 3/666 (0%)

Query: 3   AAKVALTKRADPAELRTIFLKYASIEKNGEFFMSPNDFVTRYLNIFGESQPNPKTVELLS 62
           A KV  TKR DP ELR IFL+YAS E +GE +M+P DFV RYL ++ +   NPK V+LL+
Sbjct: 2   AVKVQTTKRGDPHELRNIFLQYASTEVDGERYMTPEDFVQRYLGLYNDPNSNPKIVQLLA 61

Query: 63  GVVDQTKDGLISFQEFVAFESVLCAPDALFMVAFQLFDKAGKGEVTFEDVKQVFGQTTIH 122
           GV DQTKDGLIS+QEF+AFESVLCAPD++F+VAFQLFDK+G GEVTFE+VK++FGQT IH
Sbjct: 62  GVADQTKDGLISYQEFLAFESVLCAPDSMFIVAFQLFDKSGNGEVTFENVKEIFGQTIIH 121

Query: 123 QHIPFNWDSEFVQLHFGKERKRHLTYAEFTQFLLEIQLEHAKQAFVQRDNARTGRVTAID 182
            HIPFNWD EF++LHFG  RK+HL Y EFTQFL E+QLEHA+QAF  +D +++G ++ +D
Sbjct: 122 HHIPFNWDCEFIRLHFGHNRKKHLNYTEFTQFLQELQLEHARQAFALKDKSKSGMISGLD 181

Query: 183 FRDIMVTIRPHVLTPFVEECLVAAAGGTTSHQVSFSYFNGFNSLLNNMELIRKIYSTLAG 242
           F DIMVTIR H+LTPFVEE LV+AAGG+ SHQVSFSYFN FNSLLNNMEL+RKIYSTLAG
Sbjct: 182 FSDIMVTIRSHMLTPFVEENLVSAAGGSISHQVSFSYFNAFNSLLNNMELVRKIYSTLAG 241

Query: 243 TRKDVEVTKEEFVLAAQKFGQVTPMEVDILFQLADLYEPRGRMTLADIERIAPLEEGTLP 302
           TRKDVEVTKEEF  +A ++GQVTP+E+DIL+QLADLY   GR+TLADIERIAPL EG LP
Sbjct: 242 TRKDVEVTKEEFAQSAIRYGQVTPLEIDILYQLADLYNASGRLTLADIERIAPLAEGALP 301

Query: 303 FNLAEAQRQKASGDSARPVLLQVAESAYRFGLGSVAGAVGATAVYPIDLVKTRMQNQRST 362
           +NLAE QRQ++ G   RP+ LQ+AESAYRF LGSVAGAVGATAVYPIDLVKTRMQNQR +
Sbjct: 302 YNLAELQRQQSPG-LGRPIWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGS 360

Query: 363 GSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHK 422
           GS VGELMYKNSFDCFKKVLRYEGFFGLYRGL+PQL+GVAPEKAIKLTVNDFVRDKF  +
Sbjct: 361 GSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRR 420

Query: 423 DGSVPLAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGI 482
           DGSVPL AE+LAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSAL+V+RDLG FG+
Sbjct: 421 DGSVPLPAEVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDLGIFGL 480

Query: 483 YKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPAD 542
           YKGAKACFLRDIPFSAIYFP YAH K   A+E+G V   +LL AGA+AG+PAASLVTPAD
Sbjct: 481 YKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNLLAAGAMAGVPAASLVTPAD 540

Query: 543 VIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYEL 602
           VIKTRLQVAARAGQTTYSGVIDCFRKILREEGP A WKG  ARVFRSSPQFGVTL+TYEL
Sbjct: 541 VIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYEL 600

Query: 603 LQRWFYIDFGGVKPMGSEPVPKSRI-NLPAPNPDHVGGYKLAVATFAGIENKFGLYLPLF 661
           LQRWFYIDFGG+KP GSEP PKSRI +LP  NPDH+GGY+LA ATFAGIENKFGLYLP F
Sbjct: 601 LQRWFYIDFGGLKPAGSEPTPKSRIADLPPANPDHIGGYRLATATFAGIENKFGLYLPKF 660

Query: 662 K-PSVS 666
           K PSV+
Sbjct: 661 KSPSVA 666


>gi|13375983 mitochondrial glutamate carrier 1 [Homo sapiens]
          Length = 323

 Score =  213 bits (541), Expect = 6e-55
 Identities = 127/299 (42%), Positives = 164/299 (54%), Gaps = 36/299 (12%)

Query: 335 GSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGL 394
           G +AG +G T V+PIDL KTR+QNQ++     G+ +Y +  DC  K +R EG+FG+YRG 
Sbjct: 15  GGIAGLIGVTCVFPIDLAKTRLQNQQN-----GQRVYTSMSDCLIKTVRSEGYFGMYRGA 69

Query: 395 LPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQVIFTNPLEIVKI 454
              L  V PEKAIKL  NDF R +       + L  E+LAG  AG  QVI T P+E++KI
Sbjct: 70  AVNLTLVTPEKAIKLAANDFFRHQLSKDGQKLTLLKEMLAGCGAGTCQVIVTTPMEMLKI 129

Query: 455 RLQVAGEIT-------------------------TGPRVSALSVVRDL----GFFGIYKG 485
           +LQ AG I                            PR +A  + RDL    G  G+YKG
Sbjct: 130 QLQDAGRIAAQRKILAAQGQLSAQGGAQPSVEAPAAPRPTATQLTRDLLRSRGIAGLYKG 189

Query: 486 AKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSL-LLAGAIAGMPAASLVTPADVI 544
             A  LRD+PFS +YFP +A++         + SP  +  LAG +AG  AA  V P DV+
Sbjct: 190 LGATLLRDVPFSVVYFPLFANLNQLGRPASEEKSPFYVSFLAGCVAGSAAAVAVNPCDVV 249

Query: 545 KTRLQVAAR-AGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYEL 602
           KTRLQ   R   + TYSG++DC RKILR EGP A  KGA  R    +P FG+  + Y L
Sbjct: 250 KTRLQSLQRGVNEDTYSGILDCARKILRHEGPSAFLKGAYCRALVIAPLFGIAQVVYFL 308



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 51/197 (25%), Positives = 79/197 (40%), Gaps = 28/197 (14%)

Query: 423 DGSVPLAAEILAGGCAGGSQVIFTNPLEIVKIRL---QVAGEITTGPRVSALSVVRDLGF 479
           D  + L A+++ GG AG   V    P+++ K RL   Q    + T      +  VR  G+
Sbjct: 3   DKQISLPAKLINGGIAGLIGVTCVFPIDLAKTRLQNQQNGQRVYTSMSDCLIKTVRSEGY 62

Query: 480 FGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVT 539
           FG+Y+GA        P  AI        +   + +  +++    +LAG  AG     + T
Sbjct: 63  FGMYRGAAVNLTLVTPEKAIKLAANDFFRHQLSKDGQKLTLLKEMLAGCGAGTCQVIVTT 122

Query: 540 PADVIKTRLQVAAR----------AGQTTYSG---------------VIDCFRKILREEG 574
           P +++K +LQ A R           GQ +  G                    R +LR  G
Sbjct: 123 PMEMLKIQLQDAGRIAAQRKILAAQGQLSAQGGAQPSVEAPAAPRPTATQLTRDLLRSRG 182

Query: 575 PKALWKGAGARVFRSSP 591
              L+KG GA + R  P
Sbjct: 183 IAGLYKGLGATLLRDVP 199



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 41/130 (31%), Positives = 58/130 (44%), Gaps = 16/130 (12%)

Query: 275 LADLYEPRGRMTLADIERIAPLEEGTLPFNLAEAQRQKASGDSARPVLLQVAESAYRFGL 334
           +A LY+  G   L D+           PF++             RP   + +     F  
Sbjct: 183 IAGLYKGLGATLLRDV-----------PFSVVYFPLFANLNQLGRPASEEKSPFYVSFLA 231

Query: 335 GSVAGAVGATAVYPIDLVKTRMQN-QRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRG 393
           G VAG+  A AV P D+VKTR+Q+ QR     V E  Y    DC +K+LR+EG     +G
Sbjct: 232 GCVAGSAAAVAVNPCDVVKTRLQSLQRG----VNEDTYSGILDCARKILRHEGPSAFLKG 287

Query: 394 LLPQLLGVAP 403
              + L +AP
Sbjct: 288 AYCRALVIAP 297



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 29/83 (34%), Positives = 46/83 (55%), Gaps = 1/83 (1%)

Query: 515 DGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEG 574
           D Q+S  + L+ G IAG+   + V P D+ KTRLQ   + GQ  Y+ + DC  K +R EG
Sbjct: 3   DKQISLPAKLINGGIAGLIGVTCVFPIDLAKTRLQ-NQQNGQRVYTSMSDCLIKTVRSEG 61

Query: 575 PKALWKGAGARVFRSSPQFGVTL 597
              +++GA   +   +P+  + L
Sbjct: 62  YFGMYRGAAVNLTLVTPEKAIKL 84


>gi|13899342 solute carrier [Homo sapiens]
          Length = 315

 Score =  205 bits (522), Expect = 1e-52
 Identities = 127/294 (43%), Positives = 159/294 (54%), Gaps = 34/294 (11%)

Query: 335 GSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGL 394
           G VAG VG T V+PIDL KTR+QNQ       G+ MYK   DC  K  R EGFFG+YRG 
Sbjct: 15  GGVAGLVGVTCVFPIDLAKTRLQNQH------GKAMYKGMIDCLMKTARAEGFFGMYRGA 68

Query: 395 LPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQVIFTNPLEIVKI 454
              L  V PEKAIKL  NDF R   M       L  E+LAG  AG  QV+ T P+E++KI
Sbjct: 69  AVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVVTCPMEMLKI 128

Query: 455 RLQVAGEI-----------------TTG---------PRVSALSVVRDLGFFGIYKGAKA 488
           +LQ AG +                 TTG           + A  ++R  G  G+Y+G  A
Sbjct: 129 QLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGLYRGLGA 188

Query: 489 CFLRDIPFSAIYFPCYAHVKASFANE-DGQVSPGSLLLAGAIAGMPAASLVTPADVIKTR 547
             LRDIPFS IYFP +A++     NE  G+ S     ++G +AG  AA  VTP DV+KTR
Sbjct: 189 TLLRDIPFSIIYFPLFANLNNLGFNELAGKASFAHSFVSGCVAGSIAAVAVTPLDVLKTR 248

Query: 548 LQVAARA-GQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTY 600
           +Q   +  G+  YSG+ DC RK+  +EGP A  KGAG R    +P FG+    Y
Sbjct: 249 IQTLKKGLGEDMYSGITDCARKLWIQEGPSAFMKGAGCRALVIAPLFGIAQGVY 302



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 27/82 (32%), Positives = 44/82 (53%), Gaps = 2/82 (2%)

Query: 524 LLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAG 583
           L+ G +AG+   + V P D+ KTRLQ   + G+  Y G+IDC  K  R EG   +++GA 
Sbjct: 12  LINGGVAGLVGVTCVFPIDLAKTRLQ--NQHGKAMYKGMIDCLMKTARAEGFFGMYRGAA 69

Query: 584 ARVFRSSPQFGVTLLTYELLQR 605
             +   +P+  + L   +  +R
Sbjct: 70  VNLTLVTPEKAIKLAANDFFRR 91



 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 50/195 (25%), Positives = 80/195 (41%), Gaps = 26/195 (13%)

Query: 421 HKDGSVPLAAEILAGGCAGGSQVIFTNPLEIVKIRL--QVAGEITTGPRVSALSVVRDLG 478
           H+D S+   A+++ GG AG   V    P+++ K RL  Q    +  G     +   R  G
Sbjct: 3   HQDLSI--TAKLINGGVAGLVGVTCVFPIDLAKTRLQNQHGKAMYKGMIDCLMKTARAEG 60

Query: 479 FFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLV 538
           FFG+Y+GA        P  AI        +     +  Q +    +LAG  AGM    + 
Sbjct: 61  FFGMYRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVVT 120

Query: 539 TPADVIKTRLQVAAR-------------AGQTTYSGVIDCFRK---------ILREEGPK 576
            P +++K +LQ A R               ++  +G     R+         +LR +G  
Sbjct: 121 CPMEMLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLA 180

Query: 577 ALWKGAGARVFRSSP 591
            L++G GA + R  P
Sbjct: 181 GLYRGLGATLLRDIP 195



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 29/78 (37%), Positives = 43/78 (55%), Gaps = 3/78 (3%)

Query: 326 AESAYRFGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYE 385
           A  A+ F  G VAG++ A AV P+D++KTR+Q  +     +GE MY    DC +K+   E
Sbjct: 219 ASFAHSFVSGCVAGSIAAVAVTPLDVLKTRIQTLKKG---LGEDMYSGITDCARKLWIQE 275

Query: 386 GFFGLYRGLLPQLLGVAP 403
           G     +G   + L +AP
Sbjct: 276 GPSAFMKGAGCRALVIAP 293


>gi|116235462 solute carrier family 25, member 45 isoform a [Homo
           sapiens]
          Length = 288

 Score =  126 bits (316), Expect = 7e-29
 Identities = 85/292 (29%), Positives = 132/292 (45%), Gaps = 26/292 (8%)

Query: 332 FGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLY 391
           F  G ++GA+G    +P D VK R+Q Q +         Y+   DC  K+ R+E   G +
Sbjct: 6   FVAGWISGALGLVLGHPFDTVKVRLQTQTT---------YRGIVDCMVKIYRHESLLGFF 56

Query: 392 RGLLPQLLGVAPEKAIKLTVND-----FVRDKFMHKDGSVPLAAEILAGGCAGGS-QVIF 445
           +G+   +  +A   ++   V               +    P    I   GC GG  Q   
Sbjct: 57  KGMSFPIASIAVVNSVLFGVYSNTLLVLTATSHQERRAQPPSYMHIFLAGCTGGFLQAYC 116

Query: 446 TNPLEIVKIRLQVAGEITT----------GPRVSALSVVRDLGFFGIYKGAKACFLRDIP 495
             P +++K+RLQ   E             GP   A S+ R+ G  G+++GA A  LRD P
Sbjct: 117 LAPFDLIKVRLQNQTEPRAQPGSPPPRYQGPVHCAASIFREEGPRGLFRGAWALTLRDTP 176

Query: 496 FSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAG 555
              IYF  Y  +   +  E    S  ++L+AG  AG+ +    TP D+IK+R+Q+     
Sbjct: 177 TVGIYFITYEGLCRQYTPEGQNPSSATVLVAGGFAGIASWVAATPLDMIKSRMQMDG-LR 235

Query: 556 QTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQRWF 607
           +  Y G++DC    +R+EG    ++G      R+ P   VT L+YE L RW+
Sbjct: 236 RRVYQGMLDCMVSSIRQEGLGVFFRGVTINSARAFPVNAVTFLSYEYLLRWW 287



 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 55/189 (29%), Positives = 88/189 (46%), Gaps = 13/189 (6%)

Query: 431 EILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACF 490
           E +AG  +G   ++  +P + VK+RLQ       G     + + R     G +KG     
Sbjct: 5   EFVAGWISGALGLVLGHPFDTVKVRLQTQ-TTYRGIVDCMVKIYRHESLLGFFKGMSFPI 63

Query: 491 LRDIPFSAIYFPCYAH---VKASFANEDGQVSPGS---LLLAGAIAGMPAASLVTPADVI 544
                 +++ F  Y++   V  + ++++ +  P S   + LAG   G   A  + P D+I
Sbjct: 64  ASIAVVNSVLFGVYSNTLLVLTATSHQERRAQPPSYMHIFLAGCTGGFLQAYCLAPFDLI 123

Query: 545 KTRLQ----VAARAGQ--TTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLL 598
           K RLQ      A+ G     Y G + C   I REEGP+ L++GA A   R +P  G+  +
Sbjct: 124 KVRLQNQTEPRAQPGSPPPRYQGPVHCAASIFREEGPRGLFRGAWALTLRDTPTVGIYFI 183

Query: 599 TYELLQRWF 607
           TYE L R +
Sbjct: 184 TYEGLCRQY 192



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 25/62 (40%), Positives = 31/62 (50%), Gaps = 5/62 (8%)

Query: 520 PGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALW 579
           P    +AG I+G     L  P D +K RLQ      QTTY G++DC  KI R E     +
Sbjct: 2   PVEEFVAGWISGALGLVLGHPFDTVKVRLQT-----QTTYRGIVDCMVKIYRHESLLGFF 56

Query: 580 KG 581
           KG
Sbjct: 57  KG 58


>gi|13449279 solute carrier family 25 (mitochondrial
           oxodicarboxylate carrier), member 21 [Homo sapiens]
          Length = 299

 Score =  122 bits (307), Expect = 8e-28
 Identities = 93/301 (30%), Positives = 144/301 (47%), Gaps = 19/301 (6%)

Query: 317 SARPVLLQVAESAYRFGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFD 376
           SA+P +  V E++ +   G  AG V    ++P+D+VKTR Q QR          YK+  D
Sbjct: 2   SAKPEVSLVREASRQIVAGGSAGLVEICLMHPLDVVKTRFQIQRCA---TDPNSYKSLVD 58

Query: 377 CFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEI---L 433
            F+ + + EG FG Y+G+LP +L   P++A+K     F  +++    G V L+  +   +
Sbjct: 59  SFRMIFQMEGLFGFYKGILPPILAETPKRAVKF----FTFEQYKKLLGYVSLSPALTFAI 114

Query: 434 AGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDL------GFFGIYKGAK 487
           AG  +G ++ I  NP E+VK+ LQ A   T   + S +   R +      G  G+ KG  
Sbjct: 115 AGLGSGLTEAIVVNPFEVVKVGLQ-ANRNTFAEQPSTVGYARQIIKKEGWGLQGLNKGLT 173

Query: 488 ACFLRDIPFSAIYFPCYAHVKASF-ANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKT 546
           A   R   F+ +YF  Y +VK     N+D  +        G ++G  A+ +  P DV K+
Sbjct: 174 ATLGRHGVFNMVYFGFYYNVKNMIPVNKDPILEFWRKFGIGLLSGTIASVINIPFDVAKS 233

Query: 547 RLQVAARA-GQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQR 605
           R+Q      G+  Y         + +EEG  AL+KG   ++ R  P   V LL YE    
Sbjct: 234 RIQGPQPVPGEIKYRTCFKTMATVYQEEGILALYKGLLPKIMRLGPGGAVMLLVYEYTYS 293

Query: 606 W 606
           W
Sbjct: 294 W 294


>gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens]
          Length = 301

 Score =  119 bits (298), Expect = 9e-27
 Identities = 93/286 (32%), Positives = 140/286 (48%), Gaps = 23/286 (8%)

Query: 337 VAGAVGATAV----YPIDLVKTRMQNQRSTGSFVGE-LMYKNSFDCFKKVLRYEGFFGLY 391
           +AG  G   +    +P+D VK R+Q Q    S  G+  MY  +FDCF+K L  EG  GLY
Sbjct: 15  LAGGFGGVCLVFVGHPLDTVKVRLQTQ--PPSLPGQPPMYSGTFDCFRKTLFREGITGLY 72

Query: 392 RGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQVIFT----N 447
           RG+   ++GV P  A+        +         V    ++ A G   G   +FT     
Sbjct: 73  RGMAAPIIGVTPMFAVCFFGFGLGKKLQQKHPEDVLSYPQLFAAGMLSG---VFTTGIMT 129

Query: 448 PLEIVKIRLQV---AGEIT-TGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPC 503
           P E +K  LQ+   +GE   TG    A  + ++ G  GIYKG     +RD+P S +YF  
Sbjct: 130 PGERIKCLLQIQASSGESKYTGTLDCAKKLYQEFGIRGIYKGTVLTLMRDVPASGMYFMT 189

Query: 504 YAHVKASFANEDGQVSPGS---LLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYS 560
           Y  +K  F  E  +VS  S   +L+AG IAG+   ++  P DV+K+R Q A        +
Sbjct: 190 YEWLKNIFTPEGKRVSELSAPRILVAGGIAGIFNWAVAIPPDVLKSRFQTAPPGKYP--N 247

Query: 561 GVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQRW 606
           G  D  R+++R+EG  +L+KG  A + R+ P      L +E+  ++
Sbjct: 248 GFRDVLRELIRDEGVTSLYKGFNAVMIRAFPANAACFLGFEVAMKF 293



 Score = 83.6 bits (205), Expect = 6e-16
 Identities = 56/185 (30%), Positives = 93/185 (50%), Gaps = 10/185 (5%)

Query: 432 ILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTG--PRVSAL------SVVRDLGFFGIY 483
           +LAGG  G   V   +PL+ VK+RLQ       G  P  S        ++ R+ G  G+Y
Sbjct: 14  LLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFRE-GITGLY 72

Query: 484 KGAKACFLRDIP-FSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPAD 542
           +G  A  +   P F+  +F      K    + +  +S   L  AG ++G+    ++TP +
Sbjct: 73  RGMAAPIIGVTPMFAVCFFGFGLGKKLQQKHPEDVLSYPQLFAAGMLSGVFTTGIMTPGE 132

Query: 543 VIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYEL 602
            IK  LQ+ A +G++ Y+G +DC +K+ +E G + ++KG    + R  P  G+  +TYE 
Sbjct: 133 RIKCLLQIQASSGESKYTGTLDCAKKLYQEFGIRGIYKGTVLTLMRDVPASGMYFMTYEW 192

Query: 603 LQRWF 607
           L+  F
Sbjct: 193 LKNIF 197



 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 34/94 (36%), Positives = 46/94 (48%), Gaps = 3/94 (3%)

Query: 512 ANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQV--AARAGQ-TTYSGVIDCFRK 568
           A++   +SP   LLAG   G+    +  P D +K RLQ    +  GQ   YSG  DCFRK
Sbjct: 2   ADQPKPISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRK 61

Query: 569 ILREEGPKALWKGAGARVFRSSPQFGVTLLTYEL 602
            L  EG   L++G  A +   +P F V    + L
Sbjct: 62  TLFREGITGLYRGMAAPIIGVTPMFAVCFFGFGL 95



 Score = 30.0 bits (66), Expect = 7.3
 Identities = 20/73 (27%), Positives = 31/73 (42%), Gaps = 8/73 (10%)

Query: 335 GSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSF-DCFKKVLRYEGFFGLYRG 393
           G +AG        P D++K+R Q             Y N F D  ++++R EG   LY+G
Sbjct: 216 GGIAGIFNWAVAIPPDVLKSRFQTAPPG-------KYPNGFRDVLRELIRDEGVTSLYKG 268

Query: 394 LLPQLLGVAPEKA 406
               ++   P  A
Sbjct: 269 FNAVMIRAFPANA 281


>gi|13775208 solute carrier family 25 (mitochondrial carrier;
           adenine nucleotide translocator), member 31 [Homo
           sapiens]
          Length = 315

 Score =  117 bits (292), Expect = 5e-26
 Identities = 83/292 (28%), Positives = 131/292 (44%), Gaps = 17/292 (5%)

Query: 335 GSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGL 394
           G VA AV  TAV PI+ VK  +Q Q S+     E  YK   DC  ++ R +GFF  +RG 
Sbjct: 27  GGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFSFWRGN 86

Query: 395 LPQLLGVAPEKAIKLTVNDFVRDKFM-----HKDGSVPLAAEILAGGCAGGSQVIFTNPL 449
           L  ++   P +A+     D  +  FM      K       A + +GG AG + +    PL
Sbjct: 87  LANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLCVVYPL 146

Query: 450 EIVKIRLQVAGEITTGPRV--------SALSVVRDLGFFGIYKGAKACFLRDIPFSAIYF 501
           +  + RL V  +I  GP            + + +  G  G+Y+G        I + A YF
Sbjct: 147 DFARTRLGV--DIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYRASYF 204

Query: 502 PCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSG 561
             Y  VK             S  +A  +    +  L  P D ++ R+ + +   +  Y G
Sbjct: 205 GAYDTVKGLLPKPKKTPFLVSFFIAQVVTTC-SGILSYPFDTVRRRMMMQSGEAKRQYKG 263

Query: 562 VIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQRWFYIDFGG 613
            +DCF KI + EG  + ++GA + V R +    + L+ Y+ ++ +F+ID GG
Sbjct: 264 TLDCFVKIYQHEGISSFFRGAFSNVLRGTGG-ALVLVLYDKIKEFFHIDIGG 314



 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 51/171 (29%), Positives = 79/171 (46%), Gaps = 15/171 (8%)

Query: 431 EILAGGCAGGSQVIFTNPLEIVKIRLQV---AGEITTGPRVSAL-----SVVRDLGFFGI 482
           ++LAGG A         P+E VK+ LQV   + +I+   R   +      + R+ GFF  
Sbjct: 23  DLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFSF 82

Query: 483 YKGAKACFLRDIPFSAIYFPC---YAHVKASFANEDGQVSPGSL--LLAGAIAGMPAASL 537
           ++G  A  +R  P  A+ F     Y  +  S  N++ Q     L  L +G  AG  +  +
Sbjct: 83  WRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLCV 142

Query: 538 VTPADVIKTRLQVAARAG--QTTYSGVIDCFRKILREEGPKALWKGAGARV 586
           V P D  +TRL V    G  +  + G+ DC  KI + +G   L++G G  V
Sbjct: 143 VYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSV 193



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 28/75 (37%), Positives = 41/75 (54%), Gaps = 4/75 (5%)

Query: 521 GSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTT----YSGVIDCFRKILREEGPK 576
           G  LLAG +A   + + V P + +K  LQV A + Q +    Y G++DC  +I RE+G  
Sbjct: 21  GKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFF 80

Query: 577 ALWKGAGARVFRSSP 591
           + W+G  A V R  P
Sbjct: 81  SFWRGNLANVIRYFP 95


>gi|46397377 chromosome 14 open reading frame 68 [Homo sapiens]
          Length = 308

 Score =  115 bits (289), Expect = 1e-25
 Identities = 94/311 (30%), Positives = 137/311 (44%), Gaps = 49/311 (15%)

Query: 332 FGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLY 391
           F  G++ G  G    YP+D VK R+Q          E  Y   + C +     E  +G Y
Sbjct: 3   FVAGAIGGVCGVAVGYPLDTVKVRIQT---------EPKYTGIWHCVRDTYHRERVWGFY 53

Query: 392 RGLLPQLLGVAPEKAIKL-----TVNDFVRDKFMHKDGSVPLAAEILAGGCAGGS-QVIF 445
           RGL   +  V+   ++        +    R ++ + D   P  A+I   GCA G  +V  
Sbjct: 54  RGLSLPVCTVSLVSSVSFGTYRHCLAHICRLRYGNPDAK-PTKADITLSGCASGLVRVFL 112

Query: 446 TNPLEIVKIRLQV-------------AGEITT----------------GPRVSALSVVRD 476
           T+P E+ K+RLQ              +G +                  GP     +V R+
Sbjct: 113 TSPTEVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVARE 172

Query: 477 LGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPG--SLLLAGAIAGMPA 534
            G  G+YKG+ A  LRD    A YF  YA V   + +  G   P    +L+AG  AG+ A
Sbjct: 173 EGLCGLYKGSSALVLRDGHSFATYFLSYA-VLCEWLSPAGHSRPDVPGVLVAGGCAGVLA 231

Query: 535 ASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFG 594
            ++ TP DVIK+RLQ   + GQ  Y G++ C    +REEGP+ L+KG      R+ P   
Sbjct: 232 WAVATPMDVIKSRLQADGQ-GQRRYRGLLHCMVTSVREEGPRVLFKGLVLNCCRAFPVNM 290

Query: 595 VTLLTYELLQR 605
           V  + YE + R
Sbjct: 291 VVFVAYEAVLR 301



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 54/212 (25%), Positives = 85/212 (40%), Gaps = 43/212 (20%)

Query: 431 EILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSAL-SVVRDL----GFFGIYKG 485
           + +AG   G   V    PL+ VK+R+Q      T P+ + +   VRD       +G Y+G
Sbjct: 2   DFVAGAIGGVCGVAVGYPLDTVKVRIQ------TEPKYTGIWHCVRDTYHRERVWGFYRG 55

Query: 486 AK-----ACFLRDIPFSAIYFPCYAHV-KASFANEDGQVSPGSLLLAGAIAGMPAASLVT 539
                     +  + F   Y  C AH+ +  + N D + +   + L+G  +G+    L +
Sbjct: 56  LSLPVCTVSLVSSVSFGT-YRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVRVFLTS 114

Query: 540 PADVIKTRLQVAARAG-------------------------QTTYSGVIDCFRKILREEG 574
           P +V K RLQ   +A                          +  Y G + C   + REEG
Sbjct: 115 PTEVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAREEG 174

Query: 575 PKALWKGAGARVFRSSPQFGVTLLTYELLQRW 606
              L+KG+ A V R    F    L+Y +L  W
Sbjct: 175 LCGLYKGSSALVLRDGHSFATYFLSYAVLCEW 206


>gi|86198310 solute carrier family 25, member 29 [Homo sapiens]
          Length = 303

 Score =  113 bits (282), Expect = 7e-25
 Identities = 83/276 (30%), Positives = 123/276 (44%), Gaps = 14/276 (5%)

Query: 329 AYRFGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFF 388
           A  F  G   G  G    +P D VK R+Q Q      V +  Y+ +  CFK +++ E   
Sbjct: 2   ALDFLAGCAGGVAGVLVGHPFDTVKVRLQVQS-----VEKPQYRGTLHCFKSIIKQESVL 56

Query: 389 GLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQVIFTNP 448
           GLY+GL   L+G+    A+   V         H     PL  + LAG  AG  Q +   P
Sbjct: 57  GLYKGLGSPLMGLTFINALVFGVQGNTLRALGHDS---PLN-QFLAGAAAGAIQCVICCP 112

Query: 449 LEIVKIRLQV--AGEITT--GPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCY 504
           +E+ K RLQ+  AG   T  G       +    G  G+ +G  +  LR+ P   +YF  Y
Sbjct: 113 MELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTY 172

Query: 505 AHVKASFANEDG-QVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVI 563
             +  +   E G ++    LLLAG  +G+ +     P DV+K+RLQ     G   Y G++
Sbjct: 173 DALTRALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQADGLRGAPRYRGIL 232

Query: 564 DCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLT 599
           DC  +  R EG +   +G  + + R+ P    T  T
Sbjct: 233 DCVHQSYRAEGWRVFTRGLASTLLRAFPVNAATFAT 268



 Score = 82.0 bits (201), Expect = 2e-15
 Identities = 59/182 (32%), Positives = 91/182 (50%), Gaps = 9/182 (4%)

Query: 428 LAAEILAGGCAGG-SQVIFTNPLEIVKIRLQVAGEITTGPRVSA---LSVVRDLGFFGIY 483
           +A + LAG CAGG + V+  +P + VK+RLQV        R +     S+++     G+Y
Sbjct: 1   MALDFLAG-CAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLY 59

Query: 484 KGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADV 543
           KG  +  +     +A+ F     V+ +     G  SP +  LAGA AG     +  P ++
Sbjct: 60  KGLGSPLMGLTFINALVFG----VQGNTLRALGHDSPLNQFLAGAAAGAIQCVICCPMEL 115

Query: 544 IKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELL 603
            KTRLQ+       TY G +DC  +I   EG + + +G  + + R +P FGV  LTY+ L
Sbjct: 116 AKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTYDAL 175

Query: 604 QR 605
            R
Sbjct: 176 TR 177


>gi|55749577 solute carrier family 25 (mitochondrial carrier;
           adenine nucleotide translocator), member 4 [Homo
           sapiens]
          Length = 298

 Score =  110 bits (274), Expect = 6e-24
 Identities = 78/273 (28%), Positives = 125/273 (45%), Gaps = 20/273 (7%)

Query: 332 FGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLY 391
           F  G VA AV  TAV PI+ VK  +Q Q ++     E  YK   DC  ++ + +GF   +
Sbjct: 12  FLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSFW 71

Query: 392 RGLLPQLLGVAPEKAIKLTVNDFVRDKFM-----HKDGSVPLAAEILAGGCAGGSQVIFT 446
           RG L  ++   P +A+     D  +  F+     HK      A  + +GG AG + + F 
Sbjct: 72  RGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLCFV 131

Query: 447 NPLEIVKIRLQVAGEITTGPRV--------SALSVVRDLGFFGIYKGAKACFLRDIPFSA 498
            PL+  + RL  A ++  G             + + +  G  G+Y+G        I + A
Sbjct: 132 YPLDFARTRL--AADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYRA 189

Query: 499 IYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVT-PADVIKTR--LQVAARAG 555
            YF  Y   K    +        S ++A ++  +  A LV+ P D ++ R  +Q   +  
Sbjct: 190 AYFGVYDTAKGMLPDPKNVHIFVSWMIAQSVTAV--AGLVSYPFDTVRRRMMMQSGRKGA 247

Query: 556 QTTYSGVIDCFRKILREEGPKALWKGAGARVFR 588
              Y+G +DC+RKI ++EG KA +KGA + V R
Sbjct: 248 DIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLR 280



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 48/172 (27%), Positives = 72/172 (41%), Gaps = 17/172 (9%)

Query: 431 EILAGGCAGGSQVIFTNPLEIVKIRLQV--------AGEITTGPRVSALSVVRDLGFFGI 482
           + LAGG A         P+E VK+ LQV        A +   G     + + ++ GF   
Sbjct: 11  DFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSF 70

Query: 483 YKGAKACFLRDIPFSAIYFPCYAHVKASFA------NEDGQVSPGSLLLAGAIAGMPAAS 536
           ++G  A  +R  P  A+ F      K  F        +  +   G+L   GA AG  +  
Sbjct: 71  WRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGA-AGATSLC 129

Query: 537 LVTPADVIKTRL--QVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARV 586
            V P D  +TRL   V   A Q  + G+ DC  KI + +G + L++G    V
Sbjct: 130 FVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSV 181



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 29/94 (30%), Positives = 46/94 (48%), Gaps = 7/94 (7%)

Query: 525 LAGAIAGMPAASLVTPADVIKTRLQVAARAGQTT----YSGVIDCFRKILREEGPKALWK 580
           LAG +A   + + V P + +K  LQV   + Q +    Y G+IDC  +I +E+G  + W+
Sbjct: 13  LAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSFWR 72

Query: 581 GAGARVFRSSPQFGVTLLTYELLQRWFYIDFGGV 614
           G  A V R    F    L +    ++  +  GGV
Sbjct: 73  GNLANVIR---YFPTQALNFAFKDKYKQLFLGGV 103


>gi|157388989 solute carrier family 25, member 36 isoform a [Homo
           sapiens]
          Length = 311

 Score =  107 bits (268), Expect = 3e-23
 Identities = 81/298 (27%), Positives = 133/298 (44%), Gaps = 34/298 (11%)

Query: 335 GSVAGAVGATAVYPIDLVKTRMQNQRST------------GSFVGELMYKNSFDCFKKVL 382
           G   G VGA    P+++VKTR+Q+   T            G+ V  ++      C K +L
Sbjct: 13  GGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLKVIL 72

Query: 383 RYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQ 442
             EG   L+RGL P L+GVAP +AI        ++K             +++   AG + 
Sbjct: 73  EKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAGFTA 132

Query: 443 VIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDL----GFFGIYKGAKACFLRDIPFSA 498
           +  TNP+ ++K RLQ+        R+ A   VR +    G  G Y+G  A +   I  + 
Sbjct: 133 ITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASY-AGISETV 191

Query: 499 IYFPCYAHVK---------ASFANEDGQVSPGS----LLLAGAIAGMPAASLVTPADVIK 545
           I+F  Y  +K         ++  N++  V   S    ++LA A +   A ++  P +V++
Sbjct: 192 IHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCATTIAYPHEVVR 251

Query: 546 TRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELL 603
           TRL    R   T Y         +++EEG  +L++G    + R  P   + + TYEL+
Sbjct: 252 TRL----REEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYELV 305



 Score = 69.7 bits (169), Expect = 8e-12
 Identities = 50/173 (28%), Positives = 77/173 (44%), Gaps = 20/173 (11%)

Query: 432 ILAGGCAGGSQVIFTNPLEIVKIRLQ---------------VAGE-----ITTGPRVSAL 471
           + AGGC G    I T PLE+VK RLQ               +AG      ++ GP     
Sbjct: 10  LFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLK 69

Query: 472 SVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAG 531
            ++   G   +++G     +   P  AIYF  Y++ K    +     S    +++ A+AG
Sbjct: 70  VILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAG 129

Query: 532 MPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGA 584
             A +   P  +IKTRLQ+ AR       G  +C RK+ + +G K  ++G  A
Sbjct: 130 FTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSA 182


>gi|156071462 solute carrier family 25, member A6 [Homo sapiens]
          Length = 298

 Score =  107 bits (267), Expect = 4e-23
 Identities = 79/292 (27%), Positives = 126/292 (43%), Gaps = 14/292 (4%)

Query: 324 QVAESAYRFGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLR 383
           Q    A  F  G +A A+  TAV PI+ VK  +Q Q ++     +  YK   DC  ++ +
Sbjct: 4   QAISFAKDFLAGGIAAAISKTAVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVRIPK 63

Query: 384 YEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFM-----HKDGSVPLAAEILAGGCA 438
            +G    +RG L  ++   P +A+     D  +  F+     H       A  + +GG A
Sbjct: 64  EQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKHTQFWRYFAGNLASGGAA 123

Query: 439 GGSQVIFTNPLEIVKIRLQV-AGEITTGPRVSAL-----SVVRDLGFFGIYKGAKACFLR 492
           G + + F  PL+  + RL    G+  T      L      + +  G  G+Y+G       
Sbjct: 124 GATSLCFVYPLDFARTRLAADVGKSGTEREFRGLGDCLVKITKSDGIRGLYQGFSVSVQG 183

Query: 493 DIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTR--LQV 550
            I + A YF  Y   K    +        S ++A  +  + A  +  P D ++ R  +Q 
Sbjct: 184 IIIYRAAYFGVYDTAKGMLPDPKNTHIVVSWMIAQTVTAV-AGVVSYPFDTVRRRMMMQS 242

Query: 551 AARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYEL 602
             +     Y+G +DC+RKI R+EG KA +KGA + V R      V +L  EL
Sbjct: 243 GRKGADIMYTGTVDCWRKIFRDEGGKAFFKGAWSNVLRGMGGAFVLVLYDEL 294


>gi|45237193 solute carrier family 25, member 44 isoform 1 [Homo
           sapiens]
          Length = 314

 Score =  104 bits (260), Expect = 2e-22
 Identities = 85/283 (30%), Positives = 131/283 (46%), Gaps = 37/283 (13%)

Query: 345 AVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPE 404
           +VYP  L++TR+Q Q+      G+ +Y  +FD F K+LR +G  GLYRG L     +   
Sbjct: 34  SVYPFTLIRTRLQVQK------GKSLYHGTFDAFIKILRADGITGLYRGFLVNTFTLISG 87

Query: 405 KAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQVIFTNPLEIVKI---------- 454
           +   +T  +  R KF+           ++AGG A       T P+++V            
Sbjct: 88  QCY-VTTYELTR-KFVADYSQSNTVKSLVAGGSASLVAQSITVPIDVVSQHLMMQRKGEK 145

Query: 455 --RLQVAGEITTGPRVSALSVVRDL--------GFFGIYKGAKACFLRDIPFSAIYFPCY 504
             R QV G    G  V A    +D+        G  G Y+G  A  L  IP SA+++P Y
Sbjct: 146 MGRFQVRGN-PEGQGVVAFGQTKDIIRQILQADGLRGFYRGYVASLLTYIPNSAVWWPFY 204

Query: 505 AHVKASFANEDGQVSPGSLLLA--GAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGV 562
                  +    +  P  +  A  G +A   A+ L  P DVI+TR+QV  +      + +
Sbjct: 205 HFYAEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQVEGK------NSI 258

Query: 563 IDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQR 605
           I  FR+++ EEGP  L KG  AR+  ++P   V ++ YE L++
Sbjct: 259 ILTFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLKK 301



 Score = 31.2 bits (69), Expect = 3.3
 Identities = 16/73 (21%), Positives = 35/73 (47%), Gaps = 10/73 (13%)

Query: 335 GSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGL 394
           G +A A  +    P+D+++TR+Q +      +           F++++  EG +GL +GL
Sbjct: 229 GPLAAATASILTNPMDVIRTRVQVEGKNSIIL----------TFRQLMAEEGPWGLMKGL 278

Query: 395 LPQLLGVAPEKAI 407
             +++   P   +
Sbjct: 279 SARIISATPSTIV 291


>gi|116235466 solute carrier family 25, member 45 isoform b [Homo
           sapiens]
          Length = 246

 Score =  103 bits (256), Expect = 7e-22
 Identities = 70/244 (28%), Positives = 110/244 (45%), Gaps = 17/244 (6%)

Query: 380 KVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVND-----FVRDKFMHKDGSVPLAAEILA 434
           K+ R+E   G ++G+   +  +A   ++   V               +    P    I  
Sbjct: 3   KIYRHESLLGFFKGMSFPIASIAVVNSVLFGVYSNTLLVLTATSHQERRAQPPSYMHIFL 62

Query: 435 GGCAGGS-QVIFTNPLEIVKIRLQVAGEITT----------GPRVSALSVVRDLGFFGIY 483
            GC GG  Q     P +++K+RLQ   E             GP   A S+ R+ G  G++
Sbjct: 63  AGCTGGFLQAYCLAPFDLIKVRLQNQTEPRAQPGSPPPRYQGPVHCAASIFREEGPRGLF 122

Query: 484 KGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADV 543
           +GA A  LRD P   IYF  Y  +   +  E    S  ++L+AG  AG+ +    TP D+
Sbjct: 123 RGAWALTLRDTPTVGIYFITYEGLCRQYTPEGQNPSSATVLVAGGFAGIASWVAATPLDM 182

Query: 544 IKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELL 603
           IK+R+Q+     +  Y G++DC    +R+EG    ++G      R+ P   VT L+YE L
Sbjct: 183 IKSRMQMDG-LRRRVYQGMLDCMVSSIRQEGLGVFFRGVTINSARAFPVNAVTFLSYEYL 241

Query: 604 QRWF 607
            RW+
Sbjct: 242 LRWW 245



 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 47/181 (25%), Positives = 79/181 (43%), Gaps = 5/181 (2%)

Query: 332 FGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGEL--MYKNSFDCFKKVLRYEGFFG 389
           F  G   G + A  + P DL+K R+QNQ    +  G     Y+    C   + R EG  G
Sbjct: 61  FLAGCTGGFLQAYCLAPFDLIKVRLQNQTEPRAQPGSPPPRYQGPVHCAASIFREEGPRG 120

Query: 390 LYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQVIFTNPL 449
           L+RG     L   P   I     + +  ++  +  +   A  ++AGG AG +  +   PL
Sbjct: 121 LFRGAWALTLRDTPTVGIYFITYEGLCRQYTPEGQNPSSATVLVAGGFAGIASWVAATPL 180

Query: 450 EIVKIRLQVAG---EITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAH 506
           +++K R+Q+ G    +  G     +S +R  G    ++G      R  P +A+ F  Y +
Sbjct: 181 DMIKSRMQMDGLRRRVYQGMLDCMVSSIRQEGLGVFFRGVTINSARAFPVNAVTFLSYEY 240

Query: 507 V 507
           +
Sbjct: 241 L 241


>gi|157388991 solute carrier family 25, member 36 isoform b [Homo
           sapiens]
          Length = 310

 Score =  102 bits (255), Expect = 9e-22
 Identities = 81/298 (27%), Positives = 132/298 (44%), Gaps = 35/298 (11%)

Query: 335 GSVAGAVGATAVYPIDLVKTRMQNQRST------------GSFVGELMYKNSFDCFKKVL 382
           G   G VGA    P+++VKTR+Q+   T            G+ V  ++      C K +L
Sbjct: 13  GGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLKVIL 72

Query: 383 RYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQ 442
             EG   L+RGL P L+GVAP +AI        ++K             +++   AG + 
Sbjct: 73  EKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAGFTA 132

Query: 443 VIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDL----GFFGIYKGAKACFLRDIPFSA 498
           +  TNP+ ++K RLQ+        R+ A   VR +    G  G Y+G  A +   I  + 
Sbjct: 133 ITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASY-AGISETV 191

Query: 499 IYFPCYAHVK---------ASFANEDGQVSPGS----LLLAGAIAGMPAASLVTPADVIK 545
           I+F  Y  +K         ++  N++  V   S    ++LA A +   A ++  P  V++
Sbjct: 192 IHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCATTIAYP-HVVR 250

Query: 546 TRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELL 603
           TRL    R   T Y         +++EEG  +L++G    + R  P   + + TYEL+
Sbjct: 251 TRL----REEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYELV 304



 Score = 69.7 bits (169), Expect = 8e-12
 Identities = 50/173 (28%), Positives = 77/173 (44%), Gaps = 20/173 (11%)

Query: 432 ILAGGCAGGSQVIFTNPLEIVKIRLQ---------------VAGE-----ITTGPRVSAL 471
           + AGGC G    I T PLE+VK RLQ               +AG      ++ GP     
Sbjct: 10  LFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLK 69

Query: 472 SVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAG 531
            ++   G   +++G     +   P  AIYF  Y++ K    +     S    +++ A+AG
Sbjct: 70  VILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAG 129

Query: 532 MPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGA 584
             A +   P  +IKTRLQ+ AR       G  +C RK+ + +G K  ++G  A
Sbjct: 130 FTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSA 182


>gi|82775373 solute carrier family 25, member 37 [Homo sapiens]
          Length = 338

 Score =  102 bits (253), Expect = 2e-21
 Identities = 83/284 (29%), Positives = 126/284 (44%), Gaps = 25/284 (8%)

Query: 335 GSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGL 394
           G++AG +  + +YP+D VKTRMQ+     S   +  Y + +   KK++R EGF+   RG+
Sbjct: 52  GAMAGILEHSVMYPVDSVKTRMQSL----SPDPKAQYTSIYGALKKIMRTEGFWRPLRGV 107

Query: 395 LPQLLGVAPEKA--------IKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQVIFT 446
              ++G  P  A        +K T+ND       H  G+  LA  I AG  A        
Sbjct: 108 NVMIMGAGPAHAMYFACYENMKRTLND-----VFHHQGNSHLANGI-AGSMATLLHDAVM 161

Query: 447 NPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAH 506
           NP E+VK RLQ+             +V R  G    Y+        +IPF +I+F  Y  
Sbjct: 162 NPAEVVKQRLQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEF 221

Query: 507 VKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQT------TYS 560
           ++    N     +P S +++G +AG  AA+  TP DV KT L        +        S
Sbjct: 222 LQEQ-VNPHRTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLS 280

Query: 561 GVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQ 604
           G+ + FR + +  G    +KG  ARV    P   ++   YE  +
Sbjct: 281 GMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFK 324



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 25/95 (26%), Positives = 46/95 (48%)

Query: 511 FANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKIL 570
           + N     S  + + AGA+AG+   S++ P D +KTR+Q  +   +  Y+ +    +KI+
Sbjct: 36  YENLPTSASVSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIM 95

Query: 571 REEGPKALWKGAGARVFRSSPQFGVTLLTYELLQR 605
           R EG     +G    +  + P   +    YE ++R
Sbjct: 96  RTEGFWRPLRGVNVMIMGAGPAHAMYFACYENMKR 130


>gi|156071459 solute carrier family 25, member 5 [Homo sapiens]
          Length = 298

 Score =  101 bits (251), Expect = 3e-21
 Identities = 74/273 (27%), Positives = 118/273 (43%), Gaps = 20/273 (7%)

Query: 332 FGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLY 391
           F  G VA A+  TAV PI+ VK  +Q Q ++     +  YK   DC  ++ + +G    +
Sbjct: 12  FLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSFW 71

Query: 392 RGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVP--------LAAEILAGGCAGGSQV 443
           RG L  ++   P +A+     D  +  F+   G V          A  + +GG AG + +
Sbjct: 72  RGNLANVIRYFPTQALNFAFKDKYKQIFL---GGVDKRTQFWLYFAGNLASGGAAGATSL 128

Query: 444 IFTNPLEIVKIRLQV------AGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFS 497
            F  PL+  + RL        A     G     + + +  G  G+Y+G        I + 
Sbjct: 129 CFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYR 188

Query: 498 AIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTR--LQVAARAG 555
           A YF  Y   K    +        S ++A  +  + A     P D ++ R  +Q   +  
Sbjct: 189 AAYFGIYDTAKGMLPDPKNTHIVISWMIAQTVTAV-AGLTSYPFDTVRRRMMMQSGRKGT 247

Query: 556 QTTYSGVIDCFRKILREEGPKALWKGAGARVFR 588
              Y+G +DC+RKI R+EG KA +KGA + V R
Sbjct: 248 DIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLR 280



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 48/179 (26%), Positives = 75/179 (41%), Gaps = 15/179 (8%)

Query: 423 DGSVPLAAEILAGGCAGGSQVIFTNPLEIVKIRLQV---AGEITTGPRVSAL-----SVV 474
           D +V  A + LAGG A         P+E VK+ LQV   + +IT   +   +      + 
Sbjct: 3   DAAVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIP 62

Query: 475 RDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSL-----LLAGAI 529
           ++ G    ++G  A  +R  P  A+ F      K  F     + +   L     L +G  
Sbjct: 63  KEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGA 122

Query: 530 AGMPAASLVTPADVIKTRL--QVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARV 586
           AG  +   V P D  +TRL   V     +  + G+ DC  KI + +G K L++G    V
Sbjct: 123 AGATSLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSV 181



 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 34/104 (32%), Positives = 49/104 (47%), Gaps = 7/104 (6%)

Query: 515 DGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTT----YSGVIDCFRKIL 570
           D  VS     LAG +A   + + V P + +K  LQV   + Q T    Y G+IDC  +I 
Sbjct: 3   DAAVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIP 62

Query: 571 REEGPKALWKGAGARVFRSSPQFGVTLLTYELLQRWFYIDFGGV 614
           +E+G  + W+G  A V R    F    L +    ++  I  GGV
Sbjct: 63  KEQGVLSFWRGNLANVIR---YFPTQALNFAFKDKYKQIFLGGV 103


>gi|7657585 mitochondrial ornithine transporter 1 [Homo sapiens]
          Length = 301

 Score =  100 bits (248), Expect = 6e-21
 Identities = 79/293 (26%), Positives = 125/293 (42%), Gaps = 30/293 (10%)

Query: 329 AYRFGLGSVAGAVGATAVY----PIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRY 384
           A +  +   AGA G TA      P D +K +MQ            +Y+   DC  K    
Sbjct: 6   AIQAAIDLTAGAAGGTACVLTGQPFDTMKVKMQTFPD--------LYRGLTDCCLKTYSQ 57

Query: 385 EGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKF-----MHKDGSVPLAAEILAGGCAG 439
            GF G Y+G  P L+    E ++      F +        + K   +       AG  A 
Sbjct: 58  VGFRGFYKGTSPALIANIAENSVLFMCYGFCQQVVRKVAGLDKQAKLSDLQNAAAGSFAS 117

Query: 440 GSQVIFTNPLEIVKIRLQVAGEITTGPRVSAL---------SVVRDLGFFGIYKGAKACF 490
               +   P E+VK RLQ   E+ T  +++           S++R  G  G Y G  +  
Sbjct: 118 AFAALVLCPTELVKCRLQTMYEMETSGKIAKSQNTVWSVIKSILRKDGPLGFYHGLSSTL 177

Query: 491 LRDIPFSAIYFPCYAHVKASFAN--EDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRL 548
           LR++P    +F  Y   ++ FA+     ++ P  L+L+G + G+     V P D IK+R+
Sbjct: 178 LREVPGYFFFFGGYELSRSFFASGRSKDELGPVPLMLSGGVGGICLWLAVYPVDCIKSRI 237

Query: 549 QVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYE 601
           QV + +G+   +G I  F  +++ EG  AL+ G    + R+ P  G   L YE
Sbjct: 238 QVLSMSGK--QAGFIRTFINVVKNEGITALYSGLKPTMIRAFPANGALFLAYE 288



 Score = 71.2 bits (173), Expect = 3e-12
 Identities = 48/202 (23%), Positives = 92/202 (45%), Gaps = 18/202 (8%)

Query: 420 MHKDGSVPLAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGF 479
           M  + ++  A ++ AG   G + V+   P + +K+++Q   ++  G     L     +GF
Sbjct: 1   MKSNPAIQAAIDLTAGAAGGTACVLTGQPFDTMKVKMQTFPDLYRGLTDCCLKTYSQVGF 60

Query: 480 FGIYKGAKACFLRDIPFSAIYFPCYAHV-----KASFANEDGQVSPGSLLLAGAIAGMPA 534
            G YKG     + +I  +++ F CY        K +  ++  ++S      AG+ A   A
Sbjct: 61  RGFYKGTSPALIANIAENSVLFMCYGFCQQVVRKVAGLDKQAKLSDLQNAAAGSFASAFA 120

Query: 535 ASLVTPADVIKTRLQV---------AARAGQTTYSGVIDCFRKILREEGPKALWKGAGAR 585
           A ++ P +++K RLQ           A++  T +S +    + ILR++GP   + G  + 
Sbjct: 121 ALVLCPTELVKCRLQTMYEMETSGKIAKSQNTVWSVI----KSILRKDGPLGFYHGLSST 176

Query: 586 VFRSSPQFGVTLLTYELLQRWF 607
           + R  P +      YEL + +F
Sbjct: 177 LLREVPGYFFFFGGYELSRSFF 198



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 6/88 (6%)

Query: 335 GSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGL 394
           G V G     AVYP+D +K+R+Q    +G   G +        F  V++ EG   LY GL
Sbjct: 216 GGVGGICLWLAVYPVDCIKSRIQVLSMSGKQAGFIR------TFINVVKNEGITALYSGL 269

Query: 395 LPQLLGVAPEKAIKLTVNDFVRDKFMHK 422
            P ++   P         ++ R   M++
Sbjct: 270 KPTMIRAFPANGALFLAYEYSRKLMMNQ 297


>gi|13994341 solute carrier family 25 member 2 [Homo sapiens]
          Length = 301

 Score =  100 bits (248), Expect = 6e-21
 Identities = 81/285 (28%), Positives = 128/285 (44%), Gaps = 32/285 (11%)

Query: 338 AGAVGATAVY----PIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRG 393
           AGA G TA      P D +K +MQ            +YK   DCF K     G  G Y+G
Sbjct: 15  AGAAGGTACVLTGQPFDTIKVKMQTFPD--------LYKGLTDCFLKTYAQVGLRGFYKG 66

Query: 394 LLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEI------LAGGCAGGSQVIFTN 447
             P L+    E ++      F + +F+ K   +   A++       AG  A     +   
Sbjct: 67  TGPALMAYVAENSVLFMCYGFCQ-QFVRKVAGMDKQAKLSDLQTAAAGSFASAFAALALC 125

Query: 448 PLEIVKIRLQVAGEITTGPRVSAL-----SVVRDL----GFFGIYKGAKACFLRDIPFSA 498
           P E+VK RLQ   E+    +++       SVV+ +    G  G Y G  +  L+++P   
Sbjct: 126 PTELVKCRLQTMYEMEMSGKIAKSHNTIWSVVKGILKKDGPLGFYHGLSSTLLQEVPGYF 185

Query: 499 IYFPCYAHVKASFAN--EDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQ 556
            +F  Y   ++ FA+     ++ P  L+L+G +AG+    +V P D IK+R+QV +  G+
Sbjct: 186 FFFGGYELSRSFFASGRSKDELGPVHLMLSGGVAGICLWLVVFPVDCIKSRIQVLSMYGK 245

Query: 557 TTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYE 601
              +G I     ++R EG  AL+ G  A + R+ P  G   + YE
Sbjct: 246 --QAGFIGTLLSVVRNEGIVALYSGLKATMIRAIPANGALFVAYE 288



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 49/201 (24%), Positives = 88/201 (43%), Gaps = 19/201 (9%)

Query: 422 KDGSVPLAAEILAGGCAGGSQVIFTN-PLEIVKIRLQVAGEITTGPRVSALSVVRDLGFF 480
           K G    AA  L  G AGG+  + T  P + +K+++Q   ++  G     L     +G  
Sbjct: 2   KSGPGIQAAIDLTAGAAGGTACVLTGQPFDTIKVKMQTFPDLYKGLTDCFLKTYAQVGLR 61

Query: 481 GIYKGAKACFLRDIPFSAIYFPCYAHV-----KASFANEDGQVSPGSLLLAGAIAGMPAA 535
           G YKG     +  +  +++ F CY        K +  ++  ++S      AG+ A   AA
Sbjct: 62  GFYKGTGPALMAYVAENSVLFMCYGFCQQFVRKVAGMDKQAKLSDLQTAAAGSFASAFAA 121

Query: 536 SLVTPADVIKTRLQV---------AARAGQTTYSGVIDCFRKILREEGPKALWKGAGARV 586
             + P +++K RLQ           A++  T +S V    + IL+++GP   + G  + +
Sbjct: 122 LALCPTELVKCRLQTMYEMEMSGKIAKSHNTIWSVV----KGILKKDGPLGFYHGLSSTL 177

Query: 587 FRSSPQFGVTLLTYELLQRWF 607
            +  P +      YEL + +F
Sbjct: 178 LQEVPGYFFFFGGYELSRSFF 198



 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 57/186 (30%), Positives = 85/186 (45%), Gaps = 23/186 (12%)

Query: 335 GSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNS--FDCFKKVLRYEGFFGLYR 392
           GS A A  A A+ P +LVK R+Q         G++   ++  +   K +L+ +G  G Y 
Sbjct: 113 GSFASAFAALALCPTELVKCRLQTMYEM-EMSGKIAKSHNTIWSVVKGILKKDGPLGFYH 171

Query: 393 GLLPQLLGVAPEK-----AIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQVIFTN 447
           GL   LL   P         +L+ + F   +   + G V L   +L+GG AG    +   
Sbjct: 172 GLSSTLLQEVPGYFFFFGGYELSRSFFASGRSKDELGPVHL---MLSGGVAGICLWLVVF 228

Query: 448 PLEIVKIRLQV-------AGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIY 500
           P++ +K R+QV       AG I T      LSVVR+ G   +Y G KA  +R IP +   
Sbjct: 229 PVDCIKSRIQVLSMYGKQAGFIGT-----LLSVVRNEGIVALYSGLKATMIRAIPANGAL 283

Query: 501 FPCYAH 506
           F  Y +
Sbjct: 284 FVAYEY 289



 Score = 36.2 bits (82), Expect = 0.10
 Identities = 25/89 (28%), Positives = 37/89 (41%), Gaps = 12/89 (13%)

Query: 335 GSVAGAVGATAVYPIDLVKTRMQNQRSTGS---FVGELMYKNSFDCFKKVLRYEGFFGLY 391
           G VAG      V+P+D +K+R+Q     G    F+G L+          V+R EG   LY
Sbjct: 216 GGVAGICLWLVVFPVDCIKSRIQVLSMYGKQAGFIGTLL---------SVVRNEGIVALY 266

Query: 392 RGLLPQLLGVAPEKAIKLTVNDFVRDKFM 420
            GL   ++   P         ++ R   M
Sbjct: 267 SGLKATMIRAIPANGALFVAYEYSRKMMM 295


>gi|14150082 mitochondrial carrier protein MGC4399 [Homo sapiens]
          Length = 321

 Score =  100 bits (248), Expect = 6e-21
 Identities = 86/300 (28%), Positives = 133/300 (44%), Gaps = 36/300 (12%)

Query: 335 GSVAGAVGATAVYPIDLVKTRMQNQRST-----------GSFVGELMYKNS------FDC 377
           G   G VGA    P++++KTR+Q+ R             G+  G  M + +      F  
Sbjct: 18  GGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPGLFQV 77

Query: 378 FKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGC 437
            K +L  EG   L+RGL P L+GVAP +A+        +++F            I + G 
Sbjct: 78  LKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPNSNIVHIFSAGS 137

Query: 438 AGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDL----GFFGIYKGAKACFLRD 493
           A        NP+ +VK R+Q+  ++    +++ L   R +    G  G Y+G  A +   
Sbjct: 138 AAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGLTASYA-G 196

Query: 494 IPFSAIYFPCYAHVK--------ASFAN--EDGQVSPGSLLLAGAIAGMPAASLVTPADV 543
           I  + I F  Y  +K        AS AN  E    S   L+ A A++   A+ +  P +V
Sbjct: 197 ISETIICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASCIAYPHEV 256

Query: 544 IKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELL 603
           I+TRL    R   T Y   +   R + REEG  A ++G  A++ R  P   + L TYEL+
Sbjct: 257 IRTRL----REEGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLSTYELI 312



 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 51/203 (25%), Positives = 87/203 (42%), Gaps = 32/203 (15%)

Query: 432 ILAGGCAGGSQVIFTNPLEIVKIRLQ------------------VAG-------EITTGP 466
           + AGGC G    IFT PLE++K RLQ                  ++G        +T G 
Sbjct: 15  LFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPGL 74

Query: 467 RVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLA 526
                S++   G   +++G     +   P  A+YF CY+  K  F   +G   P S ++ 
Sbjct: 75  FQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQF---NGIFVPNSNIVH 131

Query: 527 GAIAGMPA---ASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAG 583
              AG  A    SL+ P  ++KTR+Q+  +   +     + C R + + EG +  ++G  
Sbjct: 132 IFSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGLT 191

Query: 584 ARVFRSSPQFGVTLLTYELLQRW 606
           A  +    +  +    YE L+++
Sbjct: 192 AS-YAGISETIICFAIYESLKKY 213



 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 30/105 (28%), Positives = 42/105 (40%), Gaps = 21/105 (20%)

Query: 524 LLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTY---------------------SGV 562
           L AG   G   A    P +VIKTRLQ +  A +T Y                      G+
Sbjct: 15  LFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPGL 74

Query: 563 IDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQRWF 607
               + IL +EGPK+L++G G  +   +P   V    Y   +  F
Sbjct: 75  FQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQF 119


>gi|115430257 solute carrier family 25, member 26 [Homo sapiens]
          Length = 274

 Score = 99.0 bits (245), Expect = 1e-20
 Identities = 75/255 (29%), Positives = 117/255 (45%), Gaps = 25/255 (9%)

Query: 335 GSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGL 394
           G VAG      ++P+D +KTR+Q+ +                 F K     GF G+Y G+
Sbjct: 13  GGVAGVSVDLILFPLDTIKTRLQSPQG----------------FNKA---GGFHGIYAGV 53

Query: 395 LPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAA--EILAGGCAGGSQVIFTNPLEIV 452
               +G  P  A      ++V+  F+H D S  L     +LA         +   P E+V
Sbjct: 54  PSAAIGSFPNAAAFFITYEYVK-WFLHADSSSYLTPMKHMLAASAGEVVACLIRVPSEVV 112

Query: 453 KIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFA 512
           K R QV+    T    S  +++ + G  G+Y+G K+  LR+IPFS + FP +  +KA ++
Sbjct: 113 KQRAQVSASTRTFQIFS--NILYEEGIQGLYRGYKSTVLREIPFSLVQFPLWESLKALWS 170

Query: 513 -NEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILR 571
             +D  V      + GA AG  AA++ TP DV KTR+ +A     T    V+     + R
Sbjct: 171 WRQDHVVDSWQSAVCGAFAGGFAAAVTTPLDVAKTRIMLAKAGSSTADGNVLSVLHGVWR 230

Query: 572 EEGPKALWKGAGARV 586
            +G   L+ G   R+
Sbjct: 231 SQGLAGLFAGVFPRM 245



 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 49/163 (30%), Positives = 76/163 (46%), Gaps = 18/163 (11%)

Query: 430 AEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKAC 489
           A ++AGG AG S  +   PL+ +K RLQ           S     +  GF GIY G  + 
Sbjct: 8   AALVAGGVAGVSVDLILFPLDTIKTRLQ-----------SPQGFNKAGGFHGIYAGVPSA 56

Query: 490 FLRDIPFSAIYFPCYAHVK-ASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRL 548
            +   P +A +F  Y +VK    A+    ++P   +LA +   + A  +  P++V+K R 
Sbjct: 57  AIGSFPNAAAFFITYEYVKWFLHADSSSYLTPMKHMLAASAGEVVACLIRVPSEVVKQRA 116

Query: 549 QVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSP 591
           QV+A       +     F  IL EEG + L++G  + V R  P
Sbjct: 117 QVSAS------TRTFQIFSNILYEEGIQGLYRGYKSTVLREIP 153



 Score = 30.8 bits (68), Expect = 4.3
 Identities = 22/84 (26%), Positives = 35/84 (41%), Gaps = 16/84 (19%)

Query: 524 LLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAG 583
           L+AG +AG+    ++ P D IKTRLQ                 +   +  G   ++ G  
Sbjct: 10  LVAGGVAGVSVDLILFPLDTIKTRLQSP---------------QGFNKAGGFHGIYAGVP 54

Query: 584 ARVFRSSPQFGVTLLTYELLQRWF 607
           +    S P      +TYE + +WF
Sbjct: 55  SAAIGSFPNAAAFFITYEYV-KWF 77


>gi|21389315 solute carrier family 25 (mitochondrial carrier;
           citrate transporter), member 1 precursor [Homo sapiens]
          Length = 311

 Score = 98.6 bits (244), Expect = 2e-20
 Identities = 78/277 (28%), Positives = 134/277 (48%), Gaps = 20/277 (7%)

Query: 335 GSVAGAVGATAVYPIDLVKTRMQ-NQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRG 393
           G +AG +     +P + VKT++Q ++RS         Y+   DC ++ +R  G  GLYRG
Sbjct: 32  GGLAGGIEICITFPTEYVKTQLQLDERSHPP-----RYRGIGDCVRQTVRSHGVLGLYRG 86

Query: 394 LLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQ-VIFTNPLEIV 452
           L   L G  P+ A++  + +F+ +      G +     +L G  AG ++ V+   P+E +
Sbjct: 87  LSSLLYGSIPKAAVRFGMFEFLSNHMRDAQGRLDSTRGLLCGLGAGVAEAVVVVCPMETI 146

Query: 453 KIRLQVAGEITTGPRVSAL-----SVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHV 507
           K++  +  + +  P+          +VR+ G  G Y+G  A  L+     AI F     +
Sbjct: 147 KVKF-IHDQTSPNPKYRGFFHGVREIVREQGLKGTYQGLTATVLKQGSNQAIRFFVMTSL 205

Query: 508 KASFA--NEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQ-VAARAGQTTYSGVID 564
           +  +   N +  ++P    + GAIAG  +    TP DVIKTR+Q + A   + T+    D
Sbjct: 206 RNWYRGDNPNKPMNPLITGVFGAIAGAASVFGNTPLDVIKTRMQGLEAHKYRNTW----D 261

Query: 565 CFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYE 601
           C  +IL++EG KA +KG   R+ R      +  + Y+
Sbjct: 262 CGLQILKKEGLKAFYKGTVPRLGRVCLDVAIVFVIYD 298



 Score = 74.7 bits (182), Expect = 3e-13
 Identities = 52/182 (28%), Positives = 82/182 (45%), Gaps = 7/182 (3%)

Query: 432 ILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALS-----VVRDLGFFGIYKGA 486
           ILAGG AGG ++  T P E VK +LQ+  E +  PR   +       VR  G  G+Y+G 
Sbjct: 29  ILAGGLAGGIEICITFPTEYVKTQLQL-DERSHPPRYRGIGDCVRQTVRSHGVLGLYRGL 87

Query: 487 KACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVT-PADVIK 545
            +     IP +A+ F  +  +     +  G++     LL G  AG+  A +V  P + IK
Sbjct: 88  SSLLYGSIPKAAVRFGMFEFLSNHMRDAQGRLDSTRGLLCGLGAGVAEAVVVVCPMETIK 147

Query: 546 TRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQR 605
            +      +    Y G     R+I+RE+G K  ++G  A V +      +       L+ 
Sbjct: 148 VKFIHDQTSPNPKYRGFFHGVREIVREQGLKGTYQGLTATVLKQGSNQAIRFFVMTSLRN 207

Query: 606 WF 607
           W+
Sbjct: 208 WY 209



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 27/84 (32%), Positives = 45/84 (53%)

Query: 520 PGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALW 579
           PG  +LAG +AG     +  P + +KT+LQ+  R+    Y G+ DC R+ +R  G   L+
Sbjct: 25  PGKAILAGGLAGGIEICITFPTEYVKTQLQLDERSHPPRYRGIGDCVRQTVRSHGVLGLY 84

Query: 580 KGAGARVFRSSPQFGVTLLTYELL 603
           +G  + ++ S P+  V    +E L
Sbjct: 85  RGLSSLLYGSIPKAAVRFGMFEFL 108



 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 27/81 (33%), Positives = 44/81 (54%), Gaps = 7/81 (8%)

Query: 335 GSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGL 394
           G++AGA       P+D++KTRMQ   +         Y+N++DC  ++L+ EG    Y+G 
Sbjct: 227 GAIAGAASVFGNTPLDVIKTRMQGLEAH-------KYRNTWDCGLQILKKEGLKAFYKGT 279

Query: 395 LPQLLGVAPEKAIKLTVNDFV 415
           +P+L  V  + AI   + D V
Sbjct: 280 VPRLGRVCLDVAIVFVIYDEV 300


>gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Homo
           sapiens]
          Length = 325

 Score = 98.6 bits (244), Expect = 2e-20
 Identities = 75/280 (26%), Positives = 123/280 (43%), Gaps = 7/280 (2%)

Query: 332 FGLGSVAGAVGATAVYPIDLVKTRMQNQ-RSTGSFVGELMYKNSFDCFKKVLRYEGFFGL 390
           F  G +A  V     +P+DL KTR+Q Q +S  +   E+ Y+  F    ++ + EG   L
Sbjct: 44  FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLAL 103

Query: 391 YRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQVIFTNPLE 450
           Y G+ P LL  A    IK+ +   ++  F+ +     L   ++ G  +G       NP +
Sbjct: 104 YSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIANPTD 163

Query: 451 IVKIRLQVAGEITTGPRV-SALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKA 509
           ++KIR+Q  G +  G  + S + + +  G  G+++G      R      +  P Y   K 
Sbjct: 164 VLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKK 223

Query: 510 SFANEDGQVSPGSL--LLAGAIAGMPAASLVTPADVIKTRL--QVAARAGQTTYSGVIDC 565
                 G +    L   ++    G+  A    P DV++TR+  Q A       Y G +D 
Sbjct: 224 HLI-LSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDG 282

Query: 566 FRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQR 605
             K+ + EG  AL+KG      R  P   +  +TYE L+R
Sbjct: 283 ILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKR 322



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 36/132 (27%), Positives = 58/132 (43%), Gaps = 6/132 (4%)

Query: 481 GIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTP 540
           GI+ G    FLR + F+        H K++  + +         + G +A + A     P
Sbjct: 2   GIFPGIILIFLR-VKFATAAVIVSGHQKSTTVSHEMSGLNWKPFVYGGLASIVAEFGTFP 60

Query: 541 ADVIKTRLQVA-----ARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGV 595
            D+ KTRLQV      AR  +  Y G+     +I +EEG  AL+ G    + R +    +
Sbjct: 61  VDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSGIAPALLRQASYGTI 120

Query: 596 TLLTYELLQRWF 607
            +  Y+ L+R F
Sbjct: 121 KIGIYQSLKRLF 132


>gi|13259543 solute carrier family 25, member 14 isoform UCP5S [Homo
           sapiens]
          Length = 322

 Score = 98.6 bits (244), Expect = 2e-20
 Identities = 75/280 (26%), Positives = 123/280 (43%), Gaps = 7/280 (2%)

Query: 332 FGLGSVAGAVGATAVYPIDLVKTRMQNQ-RSTGSFVGELMYKNSFDCFKKVLRYEGFFGL 390
           F  G +A  V     +P+DL KTR+Q Q +S  +   E+ Y+  F    ++ + EG   L
Sbjct: 41  FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLAL 100

Query: 391 YRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQVIFTNPLE 450
           Y G+ P LL  A    IK+ +   ++  F+ +     L   ++ G  +G       NP +
Sbjct: 101 YSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIANPTD 160

Query: 451 IVKIRLQVAGEITTGPRV-SALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKA 509
           ++KIR+Q  G +  G  + S + + +  G  G+++G      R      +  P Y   K 
Sbjct: 161 VLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKK 220

Query: 510 SFANEDGQVSPGSL--LLAGAIAGMPAASLVTPADVIKTRL--QVAARAGQTTYSGVIDC 565
                 G +    L   ++    G+  A    P DV++TR+  Q A       Y G +D 
Sbjct: 221 HLI-LSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDG 279

Query: 566 FRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQR 605
             K+ + EG  AL+KG      R  P   +  +TYE L+R
Sbjct: 280 ILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKR 319



 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 36/132 (27%), Positives = 58/132 (43%), Gaps = 9/132 (6%)

Query: 481 GIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTP 540
           GI+ G    FLR + F+        H K++  + +         + G +A + A     P
Sbjct: 2   GIFPGIILIFLR-VKFATA---AVIHQKSTTVSHEMSGLNWKPFVYGGLASIVAEFGTFP 57

Query: 541 ADVIKTRLQVA-----ARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGV 595
            D+ KTRLQV      AR  +  Y G+     +I +EEG  AL+ G    + R +    +
Sbjct: 58  VDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSGIAPALLRQASYGTI 117

Query: 596 TLLTYELLQRWF 607
            +  Y+ L+R F
Sbjct: 118 KIGIYQSLKRLF 129


>gi|149274643 solute carrier family 25, member 28 [Homo sapiens]
          Length = 364

 Score = 97.8 bits (242), Expect = 3e-20
 Identities = 77/279 (27%), Positives = 122/279 (43%), Gaps = 16/279 (5%)

Query: 335 GSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGL 394
           G+VAG +    +YPID VKTRMQ+ +   +      Y+N  +   +++R EG +   RGL
Sbjct: 79  GAVAGILEHCVMYPIDCVKTRMQSLQPDPA----ARYRNVLEALWRIIRTEGLWRPMRGL 134

Query: 395 LPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQVIF----TNPLE 450
                G  P  A+     + ++      D   P     +A G AG    +      NP E
Sbjct: 135 NVTATGAGPAHALYFACYEKLKKTL--SDVIHPGGNSHIANGAAGCVATLLHDAAMNPAE 192

Query: 451 IVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKAS 510
           +VK R+Q+             +V ++ G    Y+        ++PF AI+F  Y  ++  
Sbjct: 193 VVKQRMQMYNSPYHRVTDCVRAVWQNEGAGAFYRSYTTQLTMNVPFQAIHFMTYEFLQEH 252

Query: 511 FANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTY-----SGVIDC 565
           F N   + +P S +L+GA AG  AA+  TP DV KT L         ++     +G+   
Sbjct: 253 F-NPQRRYNPSSHVLSGACAGAVAAAATTPLDVCKTLLNTQESLALNSHITGHITGMASA 311

Query: 566 FRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQ 604
           FR + +  G  A ++G  ARV    P   +    YE  +
Sbjct: 312 FRTVYQVGGVTAYFRGVQARVIYQIPSTAIAWSVYEFFK 350



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 45/189 (23%), Positives = 84/189 (44%), Gaps = 16/189 (8%)

Query: 428 LAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALS----VVRDLGFFGIY 483
           +   ++AG  AG  +     P++ VK R+Q           + L     ++R  G +   
Sbjct: 72  VTTHMVAGAVAGILEHCVMYPIDCVKTRMQSLQPDPAARYRNVLEALWRIIRTEGLWRPM 131

Query: 484 KGAKACFLRDIPFSAIYFPCYAHVKASFANE-----DGQVSPGSLLLAGAIAGMPAASLV 538
           +G         P  A+YF CY  +K + ++      +  ++ G+   AG +A +   + +
Sbjct: 132 RGLNVTATGAGPAHALYFACYEKLKKTLSDVIHPGGNSHIANGA---AGCVATLLHDAAM 188

Query: 539 TPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLL 598
            PA+V+K R+Q+      + Y  V DC R + + EG  A ++    ++  + P   +  +
Sbjct: 189 NPAEVVKQRMQMY----NSPYHRVTDCVRAVWQNEGAGAFYRSYTTQLTMNVPFQAIHFM 244

Query: 599 TYELLQRWF 607
           TYE LQ  F
Sbjct: 245 TYEFLQEHF 253


>gi|7706306 solute carrier family 25, member 39 isoform b [Homo
           sapiens]
          Length = 351

 Score = 96.7 bits (239), Expect = 6e-20
 Identities = 74/246 (30%), Positives = 117/246 (47%), Gaps = 10/246 (4%)

Query: 371 YKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAA 430
           +  + D F K++R+EG   L+ GL   L+   P  AI  T  D ++     +  +  L A
Sbjct: 96  FTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYA 155

Query: 431 EILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACF 490
            ++AG  A    V   +PLE+++ +LQ              + V   G+  ++ G     
Sbjct: 156 PMVAGALARLGTVTVISPLELMRTKLQAQHVSYRELGACVRTAVAQGGWRSLWLGWGPTA 215

Query: 491 LRDIPFSAIYFPCYAHVKA---SFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTR 547
           LRD+PFSA+Y+  Y  VK+    F  +D Q S G   +AG I+G  AA L  P DV+KT+
Sbjct: 216 LRDVPFSALYWFNYELVKSWLNGFRPKD-QTSVGMSFVAGGISGTVAAVLTLPFDVVKTQ 274

Query: 548 LQVAARAGQTTYSGVID------CFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYE 601
            QVA  A +      +         R+I  E G K L+ G   R+ +++P   + + TYE
Sbjct: 275 RQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYE 334

Query: 602 LLQRWF 607
             + +F
Sbjct: 335 FGKSFF 340



 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 27/92 (29%), Positives = 46/92 (50%), Gaps = 6/92 (6%)

Query: 332 FGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSF----VGELMYKNSFDCFKKVLRYEGF 387
           F  G ++G V A    P D+VKT  Q Q + G+     V  L   +++   +++    G 
Sbjct: 251 FVAGGISGTVAAVLTLPFDVVKT--QRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGT 308

Query: 388 FGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKF 419
            GL+ G LP+++  AP  AI ++  +F +  F
Sbjct: 309 KGLFAGFLPRIIKAAPSCAIMISTYEFGKSFF 340



 Score = 37.7 bits (86), Expect = 0.035
 Identities = 16/48 (33%), Positives = 26/48 (54%)

Query: 557 TTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQ 604
           T ++G +D F KI+R EG + LW G  A +  + P   +    Y+ L+
Sbjct: 94  TRFTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLK 141


>gi|219555665 solute carrier family 25, member 39 isoform a [Homo
           sapiens]
          Length = 359

 Score = 96.7 bits (239), Expect = 6e-20
 Identities = 74/246 (30%), Positives = 117/246 (47%), Gaps = 10/246 (4%)

Query: 371 YKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAA 430
           +  + D F K++R+EG   L+ GL   L+   P  AI  T  D ++     +  +  L A
Sbjct: 104 FTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYA 163

Query: 431 EILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACF 490
            ++AG  A    V   +PLE+++ +LQ              + V   G+  ++ G     
Sbjct: 164 PMVAGALARLGTVTVISPLELMRTKLQAQHVSYRELGACVRTAVAQGGWRSLWLGWGPTA 223

Query: 491 LRDIPFSAIYFPCYAHVKA---SFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTR 547
           LRD+PFSA+Y+  Y  VK+    F  +D Q S G   +AG I+G  AA L  P DV+KT+
Sbjct: 224 LRDVPFSALYWFNYELVKSWLNGFRPKD-QTSVGMSFVAGGISGTVAAVLTLPFDVVKTQ 282

Query: 548 LQVAARAGQTTYSGVID------CFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYE 601
            QVA  A +      +         R+I  E G K L+ G   R+ +++P   + + TYE
Sbjct: 283 RQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYE 342

Query: 602 LLQRWF 607
             + +F
Sbjct: 343 FGKSFF 348



 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 27/92 (29%), Positives = 46/92 (50%), Gaps = 6/92 (6%)

Query: 332 FGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSF----VGELMYKNSFDCFKKVLRYEGF 387
           F  G ++G V A    P D+VKT  Q Q + G+     V  L   +++   +++    G 
Sbjct: 259 FVAGGISGTVAAVLTLPFDVVKT--QRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGT 316

Query: 388 FGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKF 419
            GL+ G LP+++  AP  AI ++  +F +  F
Sbjct: 317 KGLFAGFLPRIIKAAPSCAIMISTYEFGKSFF 348



 Score = 37.7 bits (86), Expect = 0.035
 Identities = 16/48 (33%), Positives = 26/48 (54%)

Query: 557 TTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQ 604
           T ++G +D F KI+R EG + LW G  A +  + P   +    Y+ L+
Sbjct: 102 TRFTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLK 149


>gi|27544933 solute carrier family 25, member 16 [Homo sapiens]
          Length = 332

 Score = 96.3 bits (238), Expect = 8e-20
 Identities = 79/299 (26%), Positives = 132/299 (44%), Gaps = 26/299 (8%)

Query: 332 FGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLY 391
           F  G +AG    T V P+D VK  +Q        +G       F   + V + EGF GLY
Sbjct: 40  FLAGGIAGCCAKTTVAPLDRVKVLLQAHNHHYKHLGV------FSALRAVPQKEGFLGLY 93

Query: 392 RGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQVIFTNPLEI 451
           +G    ++ + P  AI+    +  +     K G       ++AG  AG + VI T PL++
Sbjct: 94  KGNGAMMIRIFPYGAIQFMAFEHYKTLITTKLGISGHVHRLMAGSMAGMTAVICTYPLDM 153

Query: 452 VKIRL--QVAGEITTGPRVSALSVV--RDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHV 507
           V++RL  QV GE +    + A   +  ++ GFFG Y+G     L   P++ + F  +  +
Sbjct: 154 VRVRLAFQVKGEHSYTGIIHAFKTIYAKEGGFFGFYRGLMPTILGMAPYAGVSFFTFGTL 213

Query: 508 KA-------SFANEDGQVSPGSL-------LLAGAIAGMPAASLVTPADVIKTRLQVAAR 553
           K+       +        +P  L       LL G +AG  A ++  P DV + R+Q+   
Sbjct: 214 KSVGLSHAPTLLGRPSSDNPNVLVLKTHVNLLCGGVAGAIAQTISYPFDVTRRRMQLGTV 273

Query: 554 AGQTTYSGVI-DCFRKILREEG-PKALWKGAGARVFRSSPQFGVTLLTYELLQRWFYID 610
             +      + D  + +    G  K L++G      R  P   V   TYEL++++F+++
Sbjct: 274 LPEFEKCLTMRDTMKYVYGHHGIRKGLYRGLSLNYIRCIPSQAVAFTTYELMKQFFHLN 332



 Score = 70.1 bits (170), Expect = 6e-12
 Identities = 55/213 (25%), Positives = 88/213 (41%), Gaps = 32/213 (15%)

Query: 323 LQVAESAYRFGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVL 382
           L ++   +R   GS+AG       YP+D+V+ R+  Q       GE  Y      FK + 
Sbjct: 125 LGISGHVHRLMAGSMAGMTAVICTYPLDMVRVRLAFQ-----VKGEHSYTGIIHAFKTIY 179

Query: 383 RYE-GFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRD-------KFMHKDGS-------VP 427
             E GFFG YRGL+P +LG+AP   +       ++          + +  S       + 
Sbjct: 180 AKEGGFFGFYRGLMPTILGMAPYAGVSFFTFGTLKSVGLSHAPTLLGRPSSDNPNVLVLK 239

Query: 428 LAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFF------- 480
               +L GG AG      + P ++ + R+Q+    T  P       +RD   +       
Sbjct: 240 THVNLLCGGVAGAIAQTISYPFDVTRRRMQLG---TVLPEFEKCLTMRDTMKYVYGHHGI 296

Query: 481 --GIYKGAKACFLRDIPFSAIYFPCYAHVKASF 511
             G+Y+G    ++R IP  A+ F  Y  +K  F
Sbjct: 297 RKGLYRGLSLNYIRCIPSQAVAFTTYELMKQFF 329


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.138    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,844,971
Number of Sequences: 37866
Number of extensions: 1044004
Number of successful extensions: 2976
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 71
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 2179
Number of HSP's gapped (non-prelim): 258
length of query: 675
length of database: 18,247,518
effective HSP length: 109
effective length of query: 566
effective length of database: 14,120,124
effective search space: 7991990184
effective search space used: 7991990184
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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