Search of human proteins with 75750526

Search of human proteins with 75750526

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|75750526 dual specificity phosphatase 28 [Homo sapiens]
         (176 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|75750526 dual specificity phosphatase 28 [Homo sapiens]            355   1e-98
gi|5902002 dual specificity phosphatase 14 [Homo sapiens]              96   2e-20
gi|51093845 dual specificity phosphatase 18 [Homo sapiens]             90   9e-19
gi|6005956 dual specificity phosphatase 12 [Homo sapiens]              90   1e-18
gi|37674210 slingshot 2 [Homo sapiens]                                 89   2e-18
gi|153281158 dual specificity phosphatase 8 [Homo sapiens]             89   3e-18
gi|4758204 dual specificity phosphatase 1 [Homo sapiens]               88   3e-18
gi|62865890 dual specificity phosphatase 5 [Homo sapiens]              87   6e-18
gi|239582767 slingshot homolog 3 [Homo sapiens]                        87   7e-18
gi|38372911 dual specificity phosphatase 16 [Homo sapiens]             87   7e-18
gi|29826315 dual specificity phosphatase 15 isoform a [Homo sapi...    87   7e-18
gi|239047414 slingshot 1 isoform 1 [Homo sapiens]                      84   5e-17
gi|239047498 slingshot 1 isoform 3 [Homo sapiens]                      84   5e-17
gi|239047441 slingshot 1 isoform 2 [Homo sapiens]                      84   5e-17
gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens]     84   6e-17
gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens]    84   6e-17
gi|225703077 dual specificity phosphatase 21 [Homo sapiens]            82   2e-16
gi|4758206 dual specificity phosphatase 2 [Homo sapiens]               80   1e-15
gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo sapi...    77   8e-15
gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]    77   1e-14
gi|9910432 dual specificity phosphatase 22 [Homo sapiens]              75   2e-14
gi|4503421 dual specificity phosphatase 9 [Homo sapiens]               71   4e-13
gi|13128968 dual specificity phosphatase 26 [Homo sapiens]             69   2e-12
gi|21536333 dual specificity phosphatase 10 isoform b [Homo sapi...    69   3e-12
gi|21536331 dual specificity phosphatase 10 isoform b [Homo sapi...    69   3e-12
gi|56117818 muscle-restricted dual specificity phosphatase isofo...    68   5e-12
gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo ...    63   2e-10
gi|194733759 serine/threonine/tyrosine interacting protein [Homo...    63   2e-10
gi|21687043 serine/threonine/tyrosine interacting protein [Homo ...    63   2e-10
gi|56237018 testis and skeletal muscle-specific dual specificity...    62   2e-10

>gi|75750526 dual specificity phosphatase 28 [Homo sapiens]
          Length = 176

 Score =  355 bits (910), Expect = 1e-98
 Identities = 176/176 (100%), Positives = 176/176 (100%)

Query: 1   MGPAEAGRRGAASPVPPPLVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPRA 60
           MGPAEAGRRGAASPVPPPLVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPRA
Sbjct: 1   MGPAEAGRRGAASPVPPPLVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPRA 60

Query: 61  PGVAELRVPVFDDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMR 120
           PGVAELRVPVFDDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMR
Sbjct: 61  PGVAELRVPVFDDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMR 120

Query: 121 HRGLSLAKAFQMVKSARPVAEPNPGFWSQLQKYEEALQAQSCLQGEPPALGLGPEA 176
           HRGLSLAKAFQMVKSARPVAEPNPGFWSQLQKYEEALQAQSCLQGEPPALGLGPEA
Sbjct: 121 HRGLSLAKAFQMVKSARPVAEPNPGFWSQLQKYEEALQAQSCLQGEPPALGLGPEA 176


>gi|5902002 dual specificity phosphatase 14 [Homo sapiens]
          Length = 198

 Score = 95.5 bits (236), Expect = 2e-20
 Identities = 53/157 (33%), Positives = 79/157 (50%)

Query: 19  LVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPRAPGVAELRVPVFDDPAEDL 78
           + ++  SLFLG    A     L   G+T  VN + + P    P    ++VP+ D P   +
Sbjct: 27  IAQITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNFNWPQFEYVKVPLADMPHAPI 86

Query: 79  LAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSLAKAFQMVKSARP 138
             + +     + +  R  GA LV+C  G SRSA +C AYLM+   + L +A+  VK+ RP
Sbjct: 87  GLYFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRP 146

Query: 139 VAEPNPGFWSQLQKYEEALQAQSCLQGEPPALGLGPE 175
           V  PN GFW QL  YE  L  +S ++      G+ P+
Sbjct: 147 VIRPNVGFWRQLIDYERQLFGKSTVKMVQTPYGIVPD 183


>gi|51093845 dual specificity phosphatase 18 [Homo sapiens]
          Length = 188

 Score = 90.1 bits (222), Expect = 9e-19
 Identities = 50/157 (31%), Positives = 80/157 (50%)

Query: 19  LVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPRAPGVAELRVPVFDDPAEDL 78
           L ++  SL++ +  AA  +  L+   +T+ +NVS +        +  ++VPV D P   L
Sbjct: 20  LSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTLYEDIQYMQVPVADSPNSRL 79

Query: 79  LAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSLAKAFQMVKSARP 138
               +P    + +     G  L++C  G SRSAA+C AYLM++  +SL  A    KS RP
Sbjct: 80  CDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLLDAHTWTKSCRP 139

Query: 139 VAEPNPGFWSQLQKYEEALQAQSCLQGEPPALGLGPE 175
           +  PN GFW QL  YE  L  ++ +      +G+ P+
Sbjct: 140 IIRPNSGFWEQLIHYEFQLFGKNTVHMVSSPVGMIPD 176


>gi|6005956 dual specificity phosphatase 12 [Homo sapiens]
          Length = 340

 Score = 89.7 bits (221), Expect = 1e-18
 Identities = 53/140 (37%), Positives = 78/140 (55%), Gaps = 4/140 (2%)

Query: 19  LVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPRA-PGVAELR---VPVFDDP 74
           ++ V P L+ G A A    + L  AG+T  + V  ++P  +A PGV +L    VP  D P
Sbjct: 27  MLEVQPGLYFGGAAAVAEPDHLREAGITAVLTVDSEEPSFKAGPGVEDLWRLFVPALDKP 86

Query: 75  AEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSLAKAFQMVK 134
             DLL+HL+   A +  A   G A LV+C  G SRS A+ TA+LM+   L   KA++ ++
Sbjct: 87  ETDLLSHLDRCVAFIGQARAEGRAVLVHCHAGVSRSVAIITAFLMKTDQLPFEKAYEKLQ 146

Query: 135 SARPVAEPNPGFWSQLQKYE 154
             +P A+ N GF  QL+ Y+
Sbjct: 147 ILKPEAKMNEGFEWQLKLYQ 166


>gi|37674210 slingshot 2 [Homo sapiens]
          Length = 1423

 Score = 89.4 bits (220), Expect = 2e-18
 Identities = 55/135 (40%), Positives = 75/135 (55%), Gaps = 2/135 (1%)

Query: 26  LFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPRAPGVAELR-VPVFDDPAEDLLAHLEP 84
           +FLGS   A   E L   GV   +NV+R+      PGV E   + V+D+ A DLLA+   
Sbjct: 315 VFLGSEWNASNLEDLQNRGVRYILNVTREIDN-FFPGVFEYHNIRVYDEEATDLLAYWND 373

Query: 85  TCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSLAKAFQMVKSARPVAEPNP 144
           T   +  A + G  CLV+CK G SRSA+   AY M+  G +L +A+  VK  R V +PNP
Sbjct: 374 TYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKERRTVTKPNP 433

Query: 145 GFWSQLQKYEEALQA 159
            F  QL++Y+  L A
Sbjct: 434 SFMRQLEEYQGILLA 448


>gi|153281158 dual specificity phosphatase 8 [Homo sapiens]
          Length = 625

 Score = 88.6 bits (218), Expect = 3e-18
 Identities = 55/164 (33%), Positives = 87/164 (53%), Gaps = 2/164 (1%)

Query: 14  PVPPP-LVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPRAPGVAE-LRVPVF 71
           PVP   L R+ P L+LGS +    ++ + + G++  +N S   P P     +  +RVP+ 
Sbjct: 155 PVPSVGLTRILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPKPDFICESRFMRVPIN 214

Query: 72  DDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSLAKAFQ 131
           D+  E LL  L+ +   ++ A  +    +V+C  G SRSA +  AY+M+  G+S   A++
Sbjct: 215 DNYCEKLLPWLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYR 274

Query: 132 MVKSARPVAEPNPGFWSQLQKYEEALQAQSCLQGEPPALGLGPE 175
            VK  RP   PN  F  QL +YE +L+  + LQG+P      PE
Sbjct: 275 FVKDRRPSISPNFNFLGQLLEYERSLKLLAALQGDPGTPSGTPE 318


>gi|4758204 dual specificity phosphatase 1 [Homo sapiens]
          Length = 367

 Score = 88.2 bits (217), Expect = 3e-18
 Identities = 53/161 (32%), Positives = 80/161 (49%), Gaps = 2/161 (1%)

Query: 4   AEAGRRGAASPVPPP--LVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPRAP 61
           AE+G    ++P+      V + P L+LGSA  A  ++ L   G+T  +NVS   P     
Sbjct: 157 AESGCSSCSTPLYDQGGPVEILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEG 216

Query: 62  GVAELRVPVFDDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRH 121
                 +PV D+   D+ +        +++   AGG   V+C+ G SRSA +C AYLMR 
Sbjct: 217 HYQYKSIPVEDNHKADISSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRT 276

Query: 122 RGLSLAKAFQMVKSARPVAEPNPGFWSQLQKYEEALQAQSC 162
             + L +AF+ VK  R +  PN  F  QL ++E  + A  C
Sbjct: 277 NRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAPHC 317


>gi|62865890 dual specificity phosphatase 5 [Homo sapiens]
          Length = 384

 Score = 87.4 bits (215), Expect = 6e-18
 Identities = 55/154 (35%), Positives = 77/154 (50%), Gaps = 8/154 (5%)

Query: 20  VRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPRAPGVAELRVPVFDDPAEDLL 79
           V + P L+LGSA  A   E LA   +T  +NVSR+     A  +    +PV D    D+ 
Sbjct: 180 VEILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACATHLHYKWIPVEDSHTADIS 239

Query: 80  AHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSLAKAFQMVKSARPV 139
           +H +     ++     GG  LV+C+ G SRS  +C AYLM+ +   L +AF  +K  R +
Sbjct: 240 SHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRSM 299

Query: 140 AEPNPGFWSQLQKYEEAL-------QAQSCLQGE 166
             PN GF  QL +YE  +       Q  SC QGE
Sbjct: 300 VSPNFGFMGQLLQYESEILPSTPNPQPPSC-QGE 332


>gi|239582767 slingshot homolog 3 [Homo sapiens]
          Length = 659

 Score = 87.0 bits (214), Expect = 7e-18
 Identities = 55/139 (39%), Positives = 75/139 (53%)

Query: 21  RVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPRAPGVAELRVPVFDDPAEDLLA 80
           R+ P L+LGS   A   E+L R  VT  +N++R+             V ++D+ +  LL 
Sbjct: 331 RIFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPERFTYHNVRLWDEESAQLLP 390

Query: 81  HLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSLAKAFQMVKSARPVA 140
           H + T   +EAA   G   LV+CK G SRSAA   AY M+    SL +A + V+  RP+A
Sbjct: 391 HWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRPIA 450

Query: 141 EPNPGFWSQLQKYEEALQA 159
            PNPGF  QLQ Y+  L A
Sbjct: 451 RPNPGFLRQLQIYQGILTA 469


>gi|38372911 dual specificity phosphatase 16 [Homo sapiens]
          Length = 665

 Score = 87.0 bits (214), Expect = 7e-18
 Identities = 54/153 (35%), Positives = 79/153 (51%), Gaps = 1/153 (0%)

Query: 21  RVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPR-APGVAELRVPVFDDPAEDLL 79
           R+ P+L+LG  R    +E + + G+   +N S   P P   P    LRVPV D   E +L
Sbjct: 161 RILPNLYLGCQRDVLNKELMQQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKIL 220

Query: 80  AHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSLAKAFQMVKSARPV 139
             L+ +   +E A  + G  LV+C  G SRSA +  AY+M+   +SL +A++ VK  RP 
Sbjct: 221 PWLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPT 280

Query: 140 AEPNPGFWSQLQKYEEALQAQSCLQGEPPALGL 172
             PN  F  QL  YE+ ++ Q+   G    L L
Sbjct: 281 ISPNFNFLGQLLDYEKKIKNQTGASGPKSKLKL 313


>gi|29826315 dual specificity phosphatase 15 isoform a [Homo
           sapiens]
          Length = 235

 Score = 87.0 bits (214), Expect = 7e-18
 Identities = 46/135 (34%), Positives = 71/135 (52%), Gaps = 1/135 (0%)

Query: 19  LVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPRAPGVAELRVPVFDDPAEDL 78
           + +V P L+LG+   A   +QL R  +T  +++  + P P    +  LR+PV D P   +
Sbjct: 5   MTKVLPGLYLGNFIDAKDLDQLGRNKITHIISI-HESPQPLLQDITYLRIPVADTPEVPI 63

Query: 79  LAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSLAKAFQMVKSARP 138
             H +     +      GG CLV+C  G SRS  + TAY+M   GL      + +K+ RP
Sbjct: 64  KKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKATRP 123

Query: 139 VAEPNPGFWSQLQKY 153
           +A PNPGF  QL+++
Sbjct: 124 IANPNPGFRQQLEEF 138


>gi|239047414 slingshot 1 isoform 1 [Homo sapiens]
          Length = 1049

 Score = 84.3 bits (207), Expect = 5e-17
 Identities = 52/134 (38%), Positives = 68/134 (50%)

Query: 26  LFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPRAPGVAELRVPVFDDPAEDLLAHLEPT 85
           L+LGS   A   E+L  +GV   +NV+R+         A   + V+D+   DLLAH    
Sbjct: 316 LYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDLLAHWNEA 375

Query: 86  CAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSLAKAFQMVKSARPVAEPNPG 145
              +  A R    CLV+CK G SRSA+   AY M+  G  L KA+  VK  R +  PN G
Sbjct: 376 YHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITRPNAG 435

Query: 146 FWSQLQKYEEALQA 159
           F  QL +YE  L A
Sbjct: 436 FMRQLSEYEGILDA 449


>gi|239047498 slingshot 1 isoform 3 [Homo sapiens]
          Length = 703

 Score = 84.3 bits (207), Expect = 5e-17
 Identities = 52/134 (38%), Positives = 68/134 (50%)

Query: 26  LFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPRAPGVAELRVPVFDDPAEDLLAHLEPT 85
           L+LGS   A   E+L  +GV   +NV+R+         A   + V+D+   DLLAH    
Sbjct: 327 LYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDLLAHWNEA 386

Query: 86  CAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSLAKAFQMVKSARPVAEPNPG 145
              +  A R    CLV+CK G SRSA+   AY M+  G  L KA+  VK  R +  PN G
Sbjct: 387 YHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITRPNAG 446

Query: 146 FWSQLQKYEEALQA 159
           F  QL +YE  L A
Sbjct: 447 FMRQLSEYEGILDA 460


>gi|239047441 slingshot 1 isoform 2 [Homo sapiens]
          Length = 692

 Score = 84.3 bits (207), Expect = 5e-17
 Identities = 52/134 (38%), Positives = 68/134 (50%)

Query: 26  LFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPRAPGVAELRVPVFDDPAEDLLAHLEPT 85
           L+LGS   A   E+L  +GV   +NV+R+         A   + V+D+   DLLAH    
Sbjct: 316 LYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDLLAHWNEA 375

Query: 86  CAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSLAKAFQMVKSARPVAEPNPG 145
              +  A R    CLV+CK G SRSA+   AY M+  G  L KA+  VK  R +  PN G
Sbjct: 376 YHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITRPNAG 435

Query: 146 FWSQLQKYEEALQA 159
           F  QL +YE  L A
Sbjct: 436 FMRQLSEYEGILDA 449


>gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens]
          Length = 394

 Score = 84.0 bits (206), Expect = 6e-17
 Identities = 49/143 (34%), Positives = 71/143 (49%)

Query: 20  VRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPRAPGVAELRVPVFDDPAEDLL 79
           V + P L+LGSA  A   + L   G+T  +NVS   P           +PV D+   D+ 
Sbjct: 197 VEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADIS 256

Query: 80  AHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSLAKAFQMVKSARPV 139
           +        ++A     G  LV+C+ G SRSA +C AYLM  + + L +AF+ VK  R +
Sbjct: 257 SWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSI 316

Query: 140 AEPNPGFWSQLQKYEEALQAQSC 162
             PN  F  QL ++E  + A SC
Sbjct: 317 ISPNFSFMGQLLQFESQVLATSC 339


>gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens]
          Length = 303

 Score = 84.0 bits (206), Expect = 6e-17
 Identities = 49/143 (34%), Positives = 71/143 (49%)

Query: 20  VRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPRAPGVAELRVPVFDDPAEDLL 79
           V + P L+LGSA  A   + L   G+T  +NVS   P           +PV D+   D+ 
Sbjct: 106 VEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADIS 165

Query: 80  AHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSLAKAFQMVKSARPV 139
           +        ++A     G  LV+C+ G SRSA +C AYLM  + + L +AF+ VK  R +
Sbjct: 166 SWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSI 225

Query: 140 AEPNPGFWSQLQKYEEALQAQSC 162
             PN  F  QL ++E  + A SC
Sbjct: 226 ISPNFSFMGQLLQFESQVLATSC 248


>gi|225703077 dual specificity phosphatase 21 [Homo sapiens]
          Length = 190

 Score = 82.4 bits (202), Expect = 2e-16
 Identities = 49/146 (33%), Positives = 70/146 (47%)

Query: 9   RGAASPVPPPLVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPRAPGVAELRV 68
           +G   P      ++  SLFL +  AA  +  L+   +T  VN S +       G+  ++V
Sbjct: 12  QGVQQPSIYSFSQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFEGIQYIKV 71

Query: 69  PVFDDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSLAK 128
           PV D     L    +P    +       G  L++C  G SRSA++C AYLM++  +SL  
Sbjct: 72  PVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLD 131

Query: 129 AFQMVKSARPVAEPNPGFWSQLQKYE 154
           A    KS RP+  PN GFW QL  YE
Sbjct: 132 AHTWTKSRRPIIRPNNGFWEQLINYE 157


>gi|4758206 dual specificity phosphatase 2 [Homo sapiens]
          Length = 314

 Score = 79.7 bits (195), Expect = 1e-15
 Identities = 47/135 (34%), Positives = 68/135 (50%)

Query: 20  VRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPRAPGVAELRVPVFDDPAEDLL 79
           V + P LFLGS   +   + L   G+T  +NVS   P           +PV D+   ++ 
Sbjct: 174 VEILPYLFLGSCSHSSDLQGLQACGITAVLNVSASCPNHFEGLFRYKSIPVEDNQMVEIS 233

Query: 80  AHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSLAKAFQMVKSARPV 139
           A  +     ++    +GG  LV+C+ G SRSA +C AYLM+ R + L +AF  VK  R V
Sbjct: 234 AWFQEAIGFIDWVKNSGGRVLVHCQAGISRSATICLAYLMQSRRVRLDEAFDFVKQRRGV 293

Query: 140 AEPNPGFWSQLQKYE 154
             PN  F  QL ++E
Sbjct: 294 ISPNFSFMGQLLQFE 308


>gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo
           sapiens]
          Length = 217

 Score = 77.0 bits (188), Expect = 8e-15
 Identities = 46/141 (32%), Positives = 68/141 (48%)

Query: 22  VAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPRAPGVAELRVPVFDDPAEDLLAH 81
           + P L LGS  AA   + L +  VT  +NV+               + + D P  ++L++
Sbjct: 69  IKPWLLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSISILDLPETNILSY 128

Query: 82  LEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSLAKAFQMVKSARPVAE 141
                  +E A R  G  LV+C  G SR+AA+   +LM     S   AF +VK+ARP   
Sbjct: 129 FPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPSIC 188

Query: 142 PNPGFWSQLQKYEEALQAQSC 162
           PN GF  QL+ Y+E  ++  C
Sbjct: 189 PNSGFMEQLRTYQEGKESNKC 209


>gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]
          Length = 482

 Score = 76.6 bits (187), Expect = 1e-14
 Identities = 50/164 (30%), Positives = 80/164 (48%), Gaps = 13/164 (7%)

Query: 7   GRRGAASPVPPP-----------LVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQ 55
           G   A+S +P P           L  + P LFLG+ + A   + + R  +   +NV+   
Sbjct: 299 GASAASSLLPQPIPTTPDIENAELTPILPFLFLGNEQDAQDLDTMQRLNIGYVINVTTHL 358

Query: 56  PGPR-APGVAEL-RVPVFDDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAV 113
           P      G+    R+P  D   ++L  + E     +E A + G   L++C+ G SRSA +
Sbjct: 359 PLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATI 418

Query: 114 CTAYLMRHRGLSLAKAFQMVKSARPVAEPNPGFWSQLQKYEEAL 157
             AYLM+H  +++  A++ VK  RP+  PN  F  QL ++EE L
Sbjct: 419 VIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDL 462


>gi|9910432 dual specificity phosphatase 22 [Homo sapiens]
          Length = 184

 Score = 75.5 bits (184), Expect = 2e-14
 Identities = 43/135 (31%), Positives = 69/135 (51%), Gaps = 1/135 (0%)

Query: 21  RVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPRAPGVAELRVPVFDDPAEDLLA 80
           ++ P L++G+ + A   EQL++  VT  ++V      P   GV  L +P  D P+++L  
Sbjct: 7   KILPGLYIGNFKDARDAEQLSKNKVTHILSV-HDSARPMLEGVKYLCIPAADSPSQNLTR 65

Query: 81  HLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSLAKAFQMVKSARPVA 140
           H + +   +      G +CLV+C  G SRS  +  AY+M         A   V++ R  A
Sbjct: 66  HFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRAGRSCA 125

Query: 141 EPNPGFWSQLQKYEE 155
            PN GF  QLQ++E+
Sbjct: 126 NPNVGFQRQLQEFEK 140


>gi|4503421 dual specificity phosphatase 9 [Homo sapiens]
          Length = 384

 Score = 71.2 bits (173), Expect = 4e-13
 Identities = 47/154 (30%), Positives = 76/154 (49%), Gaps = 9/154 (5%)

Query: 16  PPPL-------VRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPG--PRAPGVAEL 66
           PPP+       V++ P+L+LGSAR +   E LA+ G+   +NV+   P    +       
Sbjct: 194 PPPVGLRASFPVQILPNLYLGSARDSANLESLAKLGIRYILNVTPNLPNFFEKNGDFHYK 253

Query: 67  RVPVFDDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSL 126
           ++P+ D  +++L          ++ A+      LV+C  G SRS  V  AYLM+   LSL
Sbjct: 254 QIPISDHWSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSL 313

Query: 127 AKAFQMVKSARPVAEPNPGFWSQLQKYEEALQAQ 160
             A+ +VK  +    PN  F  QL  +E +L+ +
Sbjct: 314 NDAYDLVKRKKSNISPNFNFMGQLLDFERSLRLE 347


>gi|13128968 dual specificity phosphatase 26 [Homo sapiens]
          Length = 211

 Score = 69.3 bits (168), Expect = 2e-12
 Identities = 51/143 (35%), Positives = 71/143 (49%), Gaps = 7/143 (4%)

Query: 22  VAPSLFLGSARAAGAEEQLARAGVTLCVNVS--RQQPGPRAP---GVAELRVPVFDDPAE 76
           V P L+LG    A    +L R G+T  +N S  R +  P A    G+  L V   D PA 
Sbjct: 65  VWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHDSPAF 124

Query: 77  DLLAHLEPTCAAMEAAV-RAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSLAKAFQMVKS 135
           D+  H +     +  A+ + GG  LV+C  G SRSA +  AYLM +  L+L +A + VK 
Sbjct: 125 DMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKVKD 184

Query: 136 ARPVAEPNPGFWSQLQKYEEALQ 158
            R +  PN GF  QL   +  L+
Sbjct: 185 HRGII-PNRGFLRQLLALDRRLR 206


>gi|21536333 dual specificity phosphatase 10 isoform b [Homo
           sapiens]
          Length = 140

 Score = 68.6 bits (166), Expect = 3e-12
 Identities = 33/91 (36%), Positives = 52/91 (57%)

Query: 67  RVPVFDDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSL 126
           R+P  D   ++L  + E     +E A + G   L++C+ G SRSA +  AYLM+H  +++
Sbjct: 30  RLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTM 89

Query: 127 AKAFQMVKSARPVAEPNPGFWSQLQKYEEAL 157
             A++ VK  RP+  PN  F  QL ++EE L
Sbjct: 90  TDAYKFVKGKRPIISPNLNFMGQLLEFEEDL 120


>gi|21536331 dual specificity phosphatase 10 isoform b [Homo
           sapiens]
          Length = 140

 Score = 68.6 bits (166), Expect = 3e-12
 Identities = 33/91 (36%), Positives = 52/91 (57%)

Query: 67  RVPVFDDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSL 126
           R+P  D   ++L  + E     +E A + G   L++C+ G SRSA +  AYLM+H  +++
Sbjct: 30  RLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTM 89

Query: 127 AKAFQMVKSARPVAEPNPGFWSQLQKYEEAL 157
             A++ VK  RP+  PN  F  QL ++EE L
Sbjct: 90  TDAYKFVKGKRPIISPNLNFMGQLLEFEEDL 120


>gi|56117818 muscle-restricted dual specificity phosphatase isoform
           1 [Homo sapiens]
          Length = 188

 Score = 67.8 bits (164), Expect = 5e-12
 Identities = 53/144 (36%), Positives = 75/144 (52%), Gaps = 8/144 (5%)

Query: 22  VAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQ----QPGPRAPG--VAELRVPVFDDPA 75
           V P+LF+G A  A    +L + G+T  +N + +    Q GP   G  V+ L VP  D P 
Sbjct: 41  VWPNLFIGDAATANNRFELWKLGITHVLNAAHKGLYCQGGPDFYGSSVSYLGVPAHDLPD 100

Query: 76  EDLLAHLEPTCAAMEAAVRAGGA-CLVYCKNGRSRSAAVCTAYLMRHRGLSLAKAFQMVK 134
            D+ A+       +  A+   GA  LV+C  G SRSA +  AYLM H+ LSL +A   V+
Sbjct: 101 FDISAYFSSAADFIHRALNTPGAKVLVHCVVGVSRSATLVLAYLMLHQRLSLRQAVITVR 160

Query: 135 SARPVAEPNPGFWSQLQKYEEALQ 158
             R V  PN GF  QL + ++ L+
Sbjct: 161 QHRWVF-PNRGFLHQLCRLDQQLR 183


>gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo
           sapiens]
          Length = 223

 Score = 62.8 bits (151), Expect = 2e-10
 Identities = 48/162 (29%), Positives = 77/162 (47%), Gaps = 7/162 (4%)

Query: 14  PVPPPLVRVAPSLFLGSARAAGAEEQ--LARAGVT--LCV--NVSRQQPGPRAPGVAE-L 66
           P+   +  + P LFLG   +A   +   L + G+T  +C+  N+      P    +   L
Sbjct: 24  PMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYL 83

Query: 67  RVPVFDDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSL 126
            + + D+P E+++     T   ++ +++ GG  LV+   G SRSAA   AY+M   G+  
Sbjct: 84  VLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKY 143

Query: 127 AKAFQMVKSARPVAEPNPGFWSQLQKYEEALQAQSCLQGEPP 168
             AF  V+  R    PN GF  QLQ+YE    A+  +Q   P
Sbjct: 144 RDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTIQMMSP 185


>gi|194733759 serine/threonine/tyrosine interacting protein [Homo
           sapiens]
          Length = 223

 Score = 62.8 bits (151), Expect = 2e-10
 Identities = 48/162 (29%), Positives = 77/162 (47%), Gaps = 7/162 (4%)

Query: 14  PVPPPLVRVAPSLFLGSARAAGAEEQ--LARAGVT--LCV--NVSRQQPGPRAPGVAE-L 66
           P+   +  + P LFLG   +A   +   L + G+T  +C+  N+      P    +   L
Sbjct: 24  PMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYL 83

Query: 67  RVPVFDDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSL 126
            + + D+P E+++     T   ++ +++ GG  LV+   G SRSAA   AY+M   G+  
Sbjct: 84  VLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKY 143

Query: 127 AKAFQMVKSARPVAEPNPGFWSQLQKYEEALQAQSCLQGEPP 168
             AF  V+  R    PN GF  QLQ+YE    A+  +Q   P
Sbjct: 144 RDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTIQMMSP 185


>gi|21687043 serine/threonine/tyrosine interacting protein [Homo
           sapiens]
          Length = 223

 Score = 62.8 bits (151), Expect = 2e-10
 Identities = 48/162 (29%), Positives = 77/162 (47%), Gaps = 7/162 (4%)

Query: 14  PVPPPLVRVAPSLFLGSARAAGAEEQ--LARAGVT--LCV--NVSRQQPGPRAPGVAE-L 66
           P+   +  + P LFLG   +A   +   L + G+T  +C+  N+      P    +   L
Sbjct: 24  PMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYL 83

Query: 67  RVPVFDDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSL 126
            + + D+P E+++     T   ++ +++ GG  LV+   G SRSAA   AY+M   G+  
Sbjct: 84  VLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKY 143

Query: 127 AKAFQMVKSARPVAEPNPGFWSQLQKYEEALQAQSCLQGEPP 168
             AF  V+  R    PN GF  QLQ+YE    A+  +Q   P
Sbjct: 144 RDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTIQMMSP 185


>gi|56237018 testis and skeletal muscle-specific dual specificity
           phosphatase isoform 6 [Homo sapiens]
          Length = 198

 Score = 62.4 bits (150), Expect = 2e-10
 Identities = 49/144 (34%), Positives = 71/144 (49%), Gaps = 9/144 (6%)

Query: 22  VAPSLFLGSARAAGAEEQLARAGVTLCVNVS----RQQPGP---RAPGVAELRVPVFDDP 74
           V PSLFLG A AA  + +L + G+T  VN +    +   G    R   +    +   D+P
Sbjct: 49  VWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNP 108

Query: 75  AEDLLAHLEPTCAAMEAAVRAG-GACLVYCKNGRSRSAAVCTAYLMRHRGLSLAKAFQMV 133
             DL  +  P    + AA+    G  LV+C  G SRSA +  A+LM    ++L +A Q V
Sbjct: 109 FFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTV 168

Query: 134 KSARPVAEPNPGFWSQLQKYEEAL 157
           ++ R +  PN GF  QLQ  +  L
Sbjct: 169 QAHRNIC-PNSGFLRQLQVLDNRL 191


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.132    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,416,316
Number of Sequences: 37866
Number of extensions: 387401
Number of successful extensions: 1601
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 65
Number of HSP's successfully gapped in prelim test: 46
Number of HSP's that attempted gapping in prelim test: 1492
Number of HSP's gapped (non-prelim): 123
length of query: 176
length of database: 18,247,518
effective HSP length: 95
effective length of query: 81
effective length of database: 14,650,248
effective search space: 1186670088
effective search space used: 1186670088
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.