Search of human proteins with 74048545

Search of human proteins with 74048545

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|74048545 leucine carboxyl methyltransferase 1 isoform b
[Homo sapiens]
         (279 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|74048545 leucine carboxyl methyltransferase 1 isoform b [Homo...   572   e-163
gi|74048434 leucine carboxyl methyltransferase 1 isoform a [Homo...   539   e-154
gi|25188199 leucine carboxyl methyltransferase 2 [Homo sapiens]       129   4e-30
gi|31982906 cingulin-like 1 [Homo sapiens]                             33   0.28 
gi|169210247 PREDICTED: similar to hCG2041551 [Homo sapiens]           29   4.0  
gi|169210132 PREDICTED: similar to hCG2041551 [Homo sapiens]           29   4.0  
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]                    29   4.0  
gi|4503231 cytochrome P450, family 3, subfamily A, polypeptide 5...    28   6.8  
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo...    28   8.9  
gi|154277116 spectrin repeat containing, nuclear envelope 1 isof...    28   8.9  
gi|83582809 integrator complex subunit 10 [Homo sapiens]               28   8.9  

>gi|74048545 leucine carboxyl methyltransferase 1 isoform b [Homo
           sapiens]
          Length = 279

 Score =  572 bits (1475), Expect = e-163
 Identities = 279/279 (100%), Positives = 279/279 (100%)

Query: 1   MATRQRESSITSCCSTSSCDADDEGVRGTCEDASLCKRFAVSIGYWHDPYIQHFVRLSKE 60
           MATRQRESSITSCCSTSSCDADDEGVRGTCEDASLCKRFAVSIGYWHDPYIQHFVRLSKE
Sbjct: 1   MATRQRESSITSCCSTSSCDADDEGVRGTCEDASLCKRFAVSIGYWHDPYIQHFVRLSKE 60

Query: 61  RKAPEINRGYFARVHGVSQLIKAFLRKTECHCQIVNLGAGMDTTFWRLKDEDLLPSKYFE 120
           RKAPEINRGYFARVHGVSQLIKAFLRKTECHCQIVNLGAGMDTTFWRLKDEDLLPSKYFE
Sbjct: 61  RKAPEINRGYFARVHGVSQLIKAFLRKTECHCQIVNLGAGMDTTFWRLKDEDLLPSKYFE 120

Query: 121 VDFPMIVTRKLHSIKLPTLLIAECVLVYMTPEQSANLLKWAANSFERAMFINYEQVNMGD 180
           VDFPMIVTRKLHSIKLPTLLIAECVLVYMTPEQSANLLKWAANSFERAMFINYEQVNMGD
Sbjct: 121 VDFPMIVTRKLHSIKLPTLLIAECVLVYMTPEQSANLLKWAANSFERAMFINYEQVNMGD 180

Query: 181 RFGQIMIENLRRRQCDLAGVETCKSLESQKERLLSNGWETASAVDMMELYNRLPRAEVSR 240
           RFGQIMIENLRRRQCDLAGVETCKSLESQKERLLSNGWETASAVDMMELYNRLPRAEVSR
Sbjct: 181 RFGQIMIENLRRRQCDLAGVETCKSLESQKERLLSNGWETASAVDMMELYNRLPRAEVSR 240

Query: 241 IESLEFLDEMELLEQLMRHYCLCWATKGGNELGLKEITY 279
           IESLEFLDEMELLEQLMRHYCLCWATKGGNELGLKEITY
Sbjct: 241 IESLEFLDEMELLEQLMRHYCLCWATKGGNELGLKEITY 279


>gi|74048434 leucine carboxyl methyltransferase 1 isoform a [Homo
           sapiens]
          Length = 334

 Score =  539 bits (1389), Expect = e-154
 Identities = 277/334 (82%), Positives = 278/334 (83%), Gaps = 55/334 (16%)

Query: 1   MATRQRESSITSCCSTSSCDADDEGVRGTCEDASLCKRFAVSIGYWHDPYIQHFVRLSKE 60
           MATRQRESSITSCCSTSSCDADDEGVRGTCEDASLCKRFAVSIGYWHDPYIQHFVRLSKE
Sbjct: 1   MATRQRESSITSCCSTSSCDADDEGVRGTCEDASLCKRFAVSIGYWHDPYIQHFVRLSKE 60

Query: 61  RKAPEINRGYFARVHGVSQLIKAFLRKTECHCQIVNLGAGMDTTFWRLKDEDLLPSKYFE 120
           RKAPEINRGYFARVHGVSQLIKAFLRKTECHCQIVNLGAGMDTTFWRLKDEDLLPSKYFE
Sbjct: 61  RKAPEINRGYFARVHGVSQLIKAFLRKTECHCQIVNLGAGMDTTFWRLKDEDLLPSKYFE 120

Query: 121 VDFPMIVTRK----------------LHS------------------------------- 133
           VDFPMIVTRK                LHS                               
Sbjct: 121 VDFPMIVTRKLHSIKCKPPLSSPILELHSEDTLQMDGHILDSKRYAVIGADLRDLSELEE 180

Query: 134 --------IKLPTLLIAECVLVYMTPEQSANLLKWAANSFERAMFINYEQVNMGDRFGQI 185
                    +LPTLLIAECVLVYMTPEQSANLLKWAANSFERAMFINYEQVNMGDRFGQI
Sbjct: 181 KLKKCNMNTQLPTLLIAECVLVYMTPEQSANLLKWAANSFERAMFINYEQVNMGDRFGQI 240

Query: 186 MIENLRRRQCDLAGVETCKSLESQKERLLSNGWETASAVDMMELYNRLPRAEVSRIESLE 245
           MIENLRRRQCDLAGVETCKSLESQKERLLSNGWETASAVDMMELYNRLPRAEVSRIESLE
Sbjct: 241 MIENLRRRQCDLAGVETCKSLESQKERLLSNGWETASAVDMMELYNRLPRAEVSRIESLE 300

Query: 246 FLDEMELLEQLMRHYCLCWATKGGNELGLKEITY 279
           FLDEMELLEQLMRHYCLCWATKGGNELGLKEITY
Sbjct: 301 FLDEMELLEQLMRHYCLCWATKGGNELGLKEITY 334


>gi|25188199 leucine carboxyl methyltransferase 2 [Homo sapiens]
          Length = 686

 Score =  129 bits (323), Expect = 4e-30
 Identities = 93/303 (30%), Positives = 135/303 (44%), Gaps = 61/303 (20%)

Query: 26  VRGTCEDASLCKRFAVSIGYWHDPYIQHFVRLSKERKAPEINRGYFARVHGVSQLIKAFL 85
           V+ T + ++L KR   + GY  DP+    V     R+AP I+RGY+ R   V   ++AFL
Sbjct: 13  VQNTNDSSALSKRSLAARGYVQDPFAALLVP-GAARRAPLIHRGYYVRARAVRHCVRAFL 71

Query: 86  R-----KTECHCQIVNLGAGMDTTFWRLKDED-LLPSKYFEVDFPMIVTRKLHSIKLPTL 139
                 +     QI++LGAG D+ ++RLK    L  +  +EVDFP +  RK   I     
Sbjct: 72  EQIGAPQAALRAQILSLGAGFDSLYFRLKTAGRLARAAVWEVDFPDVARRKAERIGETPE 131

Query: 140 LIA--------------------ECVL--------------------------------- 146
           L A                     C+L                                 
Sbjct: 132 LCALTGPFERGEPASALCFESADYCILGLDLRQLQRVEEALGAAGLDAASPTLLLAEAVL 191

Query: 147 VYMTPEQSANLLKWAANSFERAMFINYEQVNMGDRFGQIMIENLRRRQCDLAGVETCKSL 206
            Y+ PE +A L+ WAA  F  A+F+ YEQ+   D FGQ M+++ R+    L G+E    +
Sbjct: 192 TYLEPESAAALIAWAAQRFPNALFVVYEQMRPQDAFGQFMLQHFRQLNSPLHGLERFPDV 251

Query: 207 ESQKERLLSNGWETASAVDMMELYN-RLPRAEVSRIESLEFLDEMELLEQLMRHYCLCWA 265
           E+Q+ R L  GW    AVDM E Y+  LP  E  R+E++E  DE E       HY +  A
Sbjct: 252 EAQRRRFLQAGWTACGAVDMNEFYHCFLPAEERRRVENIEPFDEFEEWHLKCAHYFILAA 311

Query: 266 TKG 268
           ++G
Sbjct: 312 SRG 314


>gi|31982906 cingulin-like 1 [Homo sapiens]
          Length = 1302

 Score = 33.1 bits (74), Expect = 0.28
 Identities = 27/113 (23%), Positives = 53/113 (46%), Gaps = 8/113 (7%)

Query: 152  EQSANLLKWAANSFERAMFINYEQVNMGDRFGQIMIENLRRRQCDLAGVETCKSLESQKE 211
            +Q +  LK  +   E+   +  E  N     G+  IE L++   D+       +LE Q +
Sbjct: 916  KQLSEKLKEESEQKEQLRRLKNEMENERWHLGKT-IEKLQKEMADIVEASRTSTLELQNQ 974

Query: 212  RLLSNGWETASAVDMMELYNRLPR----AEVSRIESLEFLDEMELLEQLMRHY 260
                + ++  +  ++ E+  +L      AE SR+ +++  DEM L+E+ +R Y
Sbjct: 975  L---DEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDY 1024


>gi|169210247 PREDICTED: similar to hCG2041551 [Homo sapiens]
          Length = 289

 Score = 29.3 bits (64), Expect = 4.0
 Identities = 19/73 (26%), Positives = 30/73 (41%), Gaps = 2/73 (2%)

Query: 90  CHCQIVNLGAGMDTTFWRLKDEDLLPSKYFEVDFPMIVTRKLHSIKLPTLLIAECVLVYM 149
           CH  +V+LG  +   F  L   DL  S YF+ DF       +H +     +   C+L  +
Sbjct: 170 CHLALVHLGMLLIVVF--LASPDLFESLYFQNDFKCKAFFCMHRVMRSLSICTTCLLSML 227

Query: 150 TPEQSANLLKWAA 162
                +    W+A
Sbjct: 228 QAVAISPGTSWSA 240


>gi|169210132 PREDICTED: similar to hCG2041551 [Homo sapiens]
          Length = 222

 Score = 29.3 bits (64), Expect = 4.0
 Identities = 19/73 (26%), Positives = 30/73 (41%), Gaps = 2/73 (2%)

Query: 90  CHCQIVNLGAGMDTTFWRLKDEDLLPSKYFEVDFPMIVTRKLHSIKLPTLLIAECVLVYM 149
           CH  +V+LG  +   F  L   DL  S YF+ DF       +H +     +   C+L  +
Sbjct: 103 CHLALVHLGMLLIVVF--LASPDLFESLYFQNDFKCKAFFCMHRVMRSLSICTTCLLSML 160

Query: 150 TPEQSANLLKWAA 162
                +    W+A
Sbjct: 161 QAVAISPGTSWSA 173


>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
          Length = 1780

 Score = 29.3 bits (64), Expect = 4.0
 Identities = 19/66 (28%), Positives = 29/66 (43%), Gaps = 5/66 (7%)

Query: 195 CDLAGVETCKSLESQKERLLSNGWETASAVDMMELYNRLPRAEVSRIESLEFLDEMELLE 254
           CDLAG E     +++ ERL   G    S + + +  N L  +E S+     F   +   E
Sbjct: 379 CDLAGSERTMKTQNEGERLRETGNINTSLLTLGKCINVLKNSEKSK-----FQQHVPFRE 433

Query: 255 QLMRHY 260
             + HY
Sbjct: 434 SKLTHY 439


>gi|4503231 cytochrome P450, family 3, subfamily A, polypeptide 5
           [Homo sapiens]
          Length = 502

 Score = 28.5 bits (62), Expect = 6.8
 Identities = 23/100 (23%), Positives = 48/100 (48%), Gaps = 2/100 (2%)

Query: 141 IAECVLVYMTPEQSANLLKWAANSFERAMFINYEQVNMGDRFGQIMIENLRRRQCDLAGV 200
           + E + V + P+ + N L  + N  +++  +N +Q +  D F Q+MI++   ++ +    
Sbjct: 232 VFEALNVSLFPKDTINFLSKSVNRMKKSR-LNDKQKHRLD-FLQLMIDSQNSKETESHKA 289

Query: 201 ETCKSLESQKERLLSNGWETASAVDMMELYNRLPRAEVSR 240
            +   L +Q    +  G+ET S+V    LY      +V +
Sbjct: 290 LSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQ 329


>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2
            [Homo sapiens]
          Length = 8749

 Score = 28.1 bits (61), Expect = 8.9
 Identities = 20/71 (28%), Positives = 35/71 (49%), Gaps = 8/71 (11%)

Query: 196  DLAGV-ETCKSLESQKERLLSNG--WETASAVDMMELYNRLPRAEVSRIESLE-----FL 247
            ++AG+ E    L  +KE   S G  W+    + ++ LY+RL R    R+  LE     + 
Sbjct: 4651 EVAGLGEAVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQ 4710

Query: 248  DEMELLEQLMR 258
            +  ++ +QL R
Sbjct: 4711 EHEKMCQQLER 4721


>gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1
            [Homo sapiens]
          Length = 8797

 Score = 28.1 bits (61), Expect = 8.9
 Identities = 20/71 (28%), Positives = 35/71 (49%), Gaps = 8/71 (11%)

Query: 196  DLAGV-ETCKSLESQKERLLSNG--WETASAVDMMELYNRLPRAEVSRIESLE-----FL 247
            ++AG+ E    L  +KE   S G  W+    + ++ LY+RL R    R+  LE     + 
Sbjct: 4722 EVAGLGEAVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQ 4781

Query: 248  DEMELLEQLMR 258
            +  ++ +QL R
Sbjct: 4782 EHEKMCQQLER 4792


>gi|83582809 integrator complex subunit 10 [Homo sapiens]
          Length = 710

 Score = 28.1 bits (61), Expect = 8.9
 Identities = 19/65 (29%), Positives = 28/65 (43%), Gaps = 2/65 (3%)

Query: 204 KSLESQKERLLSNGWETASAVDMMELYNRLPRAEVSRI--ESLEFLDEMELLEQLMRHYC 261
           K++ S  E   + G      V+  EL N     E  ++  ES E L  +E L++     C
Sbjct: 378 KTMSSDDEDCSAKGRNRHIVVNKAELANSTEVLESFKLARESWELLYSLEFLDKEFTRIC 437

Query: 262 LCWAT 266
           L W T
Sbjct: 438 LAWKT 442


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.135    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,857,629
Number of Sequences: 37866
Number of extensions: 385817
Number of successful extensions: 865
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 853
Number of HSP's gapped (non-prelim): 17
length of query: 279
length of database: 18,247,518
effective HSP length: 101
effective length of query: 178
effective length of database: 14,423,052
effective search space: 2567303256
effective search space used: 2567303256
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.