Guide to the Human Genome
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Search of human proteins with 71979932

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|71979932 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 5 [Homo sapiens]
         (507 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|71979932 solute carrier family 7 (cationic amino acid transpo...  1006   0.0  
gi|33286428 solute carrier family 7 (cationic amino acid transpo...   538   e-153
gi|115648063 solute carrier family 7 (cationic amino acid transp...   484   e-137
gi|115648022 solute carrier family 7 (cationic amino acid transp...   484   e-137
gi|186910308 solute carrier family 7 member 7 [Homo sapiens]          475   e-134
gi|186910306 solute carrier family 7 member 7 [Homo sapiens]          475   e-134
gi|186910304 solute carrier family 7 member 7 [Homo sapiens]          475   e-134
gi|7657683 solute carrier family 7, (cationic amino acid transpo...   467   e-131
gi|9790235 solute carrier family 7, member 10 [Homo sapiens]          461   e-130
gi|187423910 solute carrier family 7, member 9 [Homo sapiens]         415   e-116
gi|7657591 solute carrier family 7, member 9 [Homo sapiens]           415   e-116
gi|33286430 solute carrier family 7 (cationic amino acid transpo...   322   4e-88
gi|71999149 solute carrier family 7, (cationic amino acid transp...   222   7e-58
gi|114326550 solute carrier family 7 (cationic amino acid transp...   108   9e-24
gi|114326544 solute carrier family 7 (cationic amino acid transp...   108   9e-24
gi|110347453 solute carrier family 7 (cationic amino acid transp...   108   9e-24
gi|4507047 solute carrier family 7 (cationic amino acid transpor...   100   2e-21
gi|134304858 solute carrier family 7, member 2 isoform 2 [Homo s...    98   2e-20
gi|109948288 solute carrier family 7, member 2 isoform 1 [Homo s...    97   5e-20
gi|181337167 solute carrier family 7 (cationic amino acid transp...    86   8e-17
gi|4506975 solute carrier family 12 (sodium/potassium/chloride t...    33   0.47 
gi|41406091 non-imprinted in Prader-Willi/Angelman syndrome 1 is...    33   0.61 
gi|40354216 sine oculis homeobox homolog 5 [Homo sapiens]              33   0.61 
gi|110224458 solute carrier family 12, member 6 isoform e [Homo ...    33   0.80 
gi|110224456 solute carrier family 12, member 6 isoform d [Homo ...    33   0.80 
gi|110224454 solute carrier family 12, member 6 isoform c [Homo ...    33   0.80 
gi|110224452 solute carrier family 12, member 6 isoform c [Homo ...    33   0.80 
gi|4826780 solute carrier family 12, member 6 isoform b [Homo sa...    33   0.80 
gi|110224449 solute carrier family 12, member 6 isoform a [Homo ...    33   0.80 
gi|16418463 MAS1 oncogene-like [Homo sapiens]                          32   1.4  

>gi|71979932 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 5 [Homo sapiens]
          Length = 507

 Score = 1006 bits (2602), Expect = 0.0
 Identities = 507/507 (100%), Positives = 507/507 (100%)

Query: 1   MAGAGPKRRALAAPAAEEKEEAREKMLAAKSADGSAPAGEGEGVTLQRNITLLNGVAIIV 60
           MAGAGPKRRALAAPAAEEKEEAREKMLAAKSADGSAPAGEGEGVTLQRNITLLNGVAIIV
Sbjct: 1   MAGAGPKRRALAAPAAEEKEEAREKMLAAKSADGSAPAGEGEGVTLQRNITLLNGVAIIV 60

Query: 61  GTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYM 120
           GTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYM
Sbjct: 61  GTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYM 120

Query: 121 LEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPLFPTCPVPEEAAKLVACLCVL 180
           LEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPLFPTCPVPEEAAKLVACLCVL
Sbjct: 121 LEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPLFPTCPVPEEAAKLVACLCVL 180

Query: 181 LLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDV 240
           LLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDV
Sbjct: 181 LLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDV 240

Query: 241 GNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTL 300
           GNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTL
Sbjct: 241 GNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTL 300

Query: 301 STEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLP 360
           STEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLP
Sbjct: 301 STEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLP 360

Query: 361 SILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRH 420
           SILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRH
Sbjct: 361 SILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRH 420

Query: 421 RKPELERPIKVNLALPVFFILACLFLIAVSFWKTPVECGIGFTIILSGLPVYFFGVWWKN 480
           RKPELERPIKVNLALPVFFILACLFLIAVSFWKTPVECGIGFTIILSGLPVYFFGVWWKN
Sbjct: 421 RKPELERPIKVNLALPVFFILACLFLIAVSFWKTPVECGIGFTIILSGLPVYFFGVWWKN 480

Query: 481 KPKWLLQGIFSTTVLCQKLMQVVPQET 507
           KPKWLLQGIFSTTVLCQKLMQVVPQET
Sbjct: 481 KPKWLLQGIFSTTVLCQKLMQVVPQET 507


>gi|33286428 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 8 isoform a [Homo
           sapiens]
          Length = 535

 Score =  538 bits (1385), Expect = e-153
 Identities = 263/493 (53%), Positives = 354/493 (71%), Gaps = 2/493 (0%)

Query: 16  AEEKEEAREKMLAAKSADGSAPAGEGEG-VTLQRNITLLNGVAIIVGTIIGSGIFVTPTG 74
           A  +    +K      +D S  AG G G V L++ I L++   IIVG IIGSGIFV+P G
Sbjct: 5   ARHRNNTEKKHPGGGESDASPEAGSGGGGVALKKEIGLVSACGIIVGNIIGSGIFVSPKG 64

Query: 75  VLKEAGSPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLW 134
           VL+ AGS GLAL+VW   G  ++VGALCYAELG TI KSGGDY+Y+ +++G L  FL+LW
Sbjct: 65  VLENAGSVGLALIVWIVTGFITVVGALCYAELGVTIPKSGGDYSYVKDIFGGLAGFLRLW 124

Query: 135 IELLIIRPSSQYIVALVFATYLLKPLFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAAT 194
           I +L+I P++Q ++AL F+ Y+L+PLFPTC  PE   +L+A +C+LLLT VNC SV+ AT
Sbjct: 125 IAVLVIYPTNQAVIALTFSNYVLQPLFPTCFPPESGLRLLAAICLLLLTWVNCSSVRWAT 184

Query: 195 RVQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEG-TKLDVGNIVLALYSGLFA 253
           RVQD F A KLLALALII++G VQI KG+   L+P  +FE   + D+G + LA   G FA
Sbjct: 185 RVQDIFTAGKLLALALIIIMGIVQICKGEYFWLEPKNAFENFQEPDIGLVALAFLQGSFA 244

Query: 254 YGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAV 313
           YGGWN+LN+VTEE+++PY+NLP AI IS+P+VT VYV  N+AY T +S +++L+S AVAV
Sbjct: 245 YGGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAV 304

Query: 314 DFGNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTP 373
            FG   LGVM+WI+P+ V LS FG VNGSLFTSSRLFF G+REGHLPS+L+MIH +  TP
Sbjct: 305 TFGEKLLGVMAWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTP 364

Query: 374 VPSLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRHRKPELERPIKVNL 433
           +P+L+FTC+ TLL   + D++++IN+  F N+L   + + G I LR +KP++ RPIK+NL
Sbjct: 365 IPALLFTCISTLLMLVTSDMYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINL 424

Query: 434 ALPVFFILACLFLIAVSFWKTPVECGIGFTIILSGLPVYFFGVWWKNKPKWLLQGIFSTT 493
             P+ ++L   FL+  S W  PV CGIG  I+L+G+PVYF GV+W++KPK     I   T
Sbjct: 425 LFPIIYLLFWAFLLVFSLWSEPVVCGIGLAIMLTGVPVYFLGVYWQHKPKCFSDFIELLT 484

Query: 494 VLCQKLMQVVPQE 506
           ++ QK+  VV  E
Sbjct: 485 LVSQKMCVVVYPE 497


>gi|115648063 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 6 [Homo sapiens]
          Length = 515

 Score =  484 bits (1246), Expect = e-137
 Identities = 230/443 (51%), Positives = 320/443 (72%), Gaps = 2/443 (0%)

Query: 35  SAPAGEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGV 94
           S P    E + L++ I+LLNGV+++VG +IGSGIFV+P GVL    S G++L+VWA  G+
Sbjct: 30  SPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASYGMSLIVWAIGGL 89

Query: 95  FSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFAT 154
           FS+VGALCYAELGTTI+KSG  YAY+LE +G   AF++LW+ LL++ P+ Q I+A+ FA 
Sbjct: 90  FSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEPTGQAIIAITFAN 149

Query: 155 YLLKPLFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILL 214
           Y+++P FP+C  P  A +L+A  C+ LLT VNC  VK  TRVQD F  AK++AL  II++
Sbjct: 150 YIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTFTYAKVVALIAIIVM 209

Query: 215 GFVQIGKGDVSNLDPNFSFEGTKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNL 274
           G V++ +G   +     +FEG+  D+GN+ LALYS LF+Y GW+ LNFVTEE+ NP RNL
Sbjct: 210 GLVKLCQGHSEHFQD--AFEGSSWDMGNLSLALYSALFSYSGWDTLNFVTEEIKNPERNL 267

Query: 275 PLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLS 334
           PLAI IS+PIVTL+Y+LTN+AY+T L+   +LSS+AVAV F +   G+ SW IP+ V LS
Sbjct: 268 PLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGMFSWTIPIAVALS 327

Query: 335 CFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIF 394
           CFG +N S+F SSRLFFVGSREGHLP +LSMIH +  TP+P+L+F C M L+Y   +D+F
Sbjct: 328 CFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCTMALIYLIVEDVF 387

Query: 395 SVINFFSFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVSFWKT 454
            +IN+FSF  W  V L+++G ++LR ++P+  RP+K+++  P+ F +  +FL+ V  +  
Sbjct: 388 QLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCICSVFLVIVPLFTD 447

Query: 455 PVECGIGFTIILSGLPVYFFGVW 477
            +   IG  I LSG+P YF GV+
Sbjct: 448 TINSLIGIGIALSGVPFYFMGVY 470


>gi|115648022 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 6 [Homo sapiens]
          Length = 515

 Score =  484 bits (1246), Expect = e-137
 Identities = 230/443 (51%), Positives = 320/443 (72%), Gaps = 2/443 (0%)

Query: 35  SAPAGEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGV 94
           S P    E + L++ I+LLNGV+++VG +IGSGIFV+P GVL    S G++L+VWA  G+
Sbjct: 30  SPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASYGMSLIVWAIGGL 89

Query: 95  FSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFAT 154
           FS+VGALCYAELGTTI+KSG  YAY+LE +G   AF++LW+ LL++ P+ Q I+A+ FA 
Sbjct: 90  FSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEPTGQAIIAITFAN 149

Query: 155 YLLKPLFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILL 214
           Y+++P FP+C  P  A +L+A  C+ LLT VNC  VK  TRVQD F  AK++AL  II++
Sbjct: 150 YIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTFTYAKVVALIAIIVM 209

Query: 215 GFVQIGKGDVSNLDPNFSFEGTKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNL 274
           G V++ +G   +     +FEG+  D+GN+ LALYS LF+Y GW+ LNFVTEE+ NP RNL
Sbjct: 210 GLVKLCQGHSEHFQD--AFEGSSWDMGNLSLALYSALFSYSGWDTLNFVTEEIKNPERNL 267

Query: 275 PLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLS 334
           PLAI IS+PIVTL+Y+LTN+AY+T L+   +LSS+AVAV F +   G+ SW IP+ V LS
Sbjct: 268 PLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGMFSWTIPIAVALS 327

Query: 335 CFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIF 394
           CFG +N S+F SSRLFFVGSREGHLP +LSMIH +  TP+P+L+F C M L+Y   +D+F
Sbjct: 328 CFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCTMALIYLIVEDVF 387

Query: 395 SVINFFSFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVSFWKT 454
            +IN+FSF  W  V L+++G ++LR ++P+  RP+K+++  P+ F +  +FL+ V  +  
Sbjct: 388 QLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCICSVFLVIVPLFTD 447

Query: 455 PVECGIGFTIILSGLPVYFFGVW 477
            +   IG  I LSG+P YF GV+
Sbjct: 448 TINSLIGIGIALSGVPFYFMGVY 470


>gi|186910308 solute carrier family 7 member 7 [Homo sapiens]
          Length = 511

 Score =  475 bits (1223), Expect = e-134
 Identities = 243/493 (49%), Positives = 339/493 (68%), Gaps = 9/493 (1%)

Query: 21  EAREKMLAAKSADGSAPAGEG-----EGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGV 75
           ++ E  +A++    ++P G+G     E V L++ I+LLNGV +IVG +IGSGIFV+P GV
Sbjct: 3   DSTEYEVASQPEVETSPLGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGV 62

Query: 76  LKEAGSPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWI 135
           L  + S GL+LV+WA  G+FS+ GALCYAELGTTI KSG  YAY+LE +G   AF++LW 
Sbjct: 63  LIYSASFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWT 122

Query: 136 ELLIIRPSSQYIVALVFATYLLKPLFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATR 195
            LLII P+SQ I+A+ FA Y+++PLFP+C  P  A++L+A  C+ LLT +NC  VK  T 
Sbjct: 123 SLLIIEPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTL 182

Query: 196 VQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDVGNIVLALYSGLFAYG 255
           VQD F  AK+LAL  +I+ G V++G+G  ++ +   SFEG+   VG+I LALYS LF+Y 
Sbjct: 183 VQDIFTYAKVLALIAVIVAGIVRLGQGASTHFEN--SFEGSSFAVGDIALALYSALFSYS 240

Query: 256 GWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDF 315
           GW+ LN+VTEE+ NP RNLPL+I IS+PIVT++Y+LTN+AY+T L    +L+S+AVAV F
Sbjct: 241 GWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTF 300

Query: 316 GNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVP 375
            +   G+ +WIIP+ V LSCFG +N S+  +SRLFFVGSREGHLP  + MIH +  TPVP
Sbjct: 301 ADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVP 360

Query: 376 SLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRHRKPELERPIKVNLAL 435
           SL+F  +M L+Y   +DIF +IN++SF  W  V L+I+G ++LR ++P+  RP+K+++  
Sbjct: 361 SLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFF 420

Query: 436 PVFFILACLFLIAVSFWKTPVECGIGFTIILSGLPVYF--FGVWWKNKPKWLLQGIFSTT 493
           P+ F L  +FL+AV  +   +   IG  I LSGLP YF    V    +P +L + + S T
Sbjct: 421 PIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSAT 480

Query: 494 VLCQKLMQVVPQE 506
              Q L   V  E
Sbjct: 481 RYLQVLCMSVAAE 493


>gi|186910306 solute carrier family 7 member 7 [Homo sapiens]
          Length = 511

 Score =  475 bits (1223), Expect = e-134
 Identities = 243/493 (49%), Positives = 339/493 (68%), Gaps = 9/493 (1%)

Query: 21  EAREKMLAAKSADGSAPAGEG-----EGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGV 75
           ++ E  +A++    ++P G+G     E V L++ I+LLNGV +IVG +IGSGIFV+P GV
Sbjct: 3   DSTEYEVASQPEVETSPLGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGV 62

Query: 76  LKEAGSPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWI 135
           L  + S GL+LV+WA  G+FS+ GALCYAELGTTI KSG  YAY+LE +G   AF++LW 
Sbjct: 63  LIYSASFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWT 122

Query: 136 ELLIIRPSSQYIVALVFATYLLKPLFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATR 195
            LLII P+SQ I+A+ FA Y+++PLFP+C  P  A++L+A  C+ LLT +NC  VK  T 
Sbjct: 123 SLLIIEPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTL 182

Query: 196 VQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDVGNIVLALYSGLFAYG 255
           VQD F  AK+LAL  +I+ G V++G+G  ++ +   SFEG+   VG+I LALYS LF+Y 
Sbjct: 183 VQDIFTYAKVLALIAVIVAGIVRLGQGASTHFEN--SFEGSSFAVGDIALALYSALFSYS 240

Query: 256 GWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDF 315
           GW+ LN+VTEE+ NP RNLPL+I IS+PIVT++Y+LTN+AY+T L    +L+S+AVAV F
Sbjct: 241 GWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTF 300

Query: 316 GNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVP 375
            +   G+ +WIIP+ V LSCFG +N S+  +SRLFFVGSREGHLP  + MIH +  TPVP
Sbjct: 301 ADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVP 360

Query: 376 SLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRHRKPELERPIKVNLAL 435
           SL+F  +M L+Y   +DIF +IN++SF  W  V L+I+G ++LR ++P+  RP+K+++  
Sbjct: 361 SLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFF 420

Query: 436 PVFFILACLFLIAVSFWKTPVECGIGFTIILSGLPVYF--FGVWWKNKPKWLLQGIFSTT 493
           P+ F L  +FL+AV  +   +   IG  I LSGLP YF    V    +P +L + + S T
Sbjct: 421 PIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSAT 480

Query: 494 VLCQKLMQVVPQE 506
              Q L   V  E
Sbjct: 481 RYLQVLCMSVAAE 493


>gi|186910304 solute carrier family 7 member 7 [Homo sapiens]
          Length = 511

 Score =  475 bits (1223), Expect = e-134
 Identities = 243/493 (49%), Positives = 339/493 (68%), Gaps = 9/493 (1%)

Query: 21  EAREKMLAAKSADGSAPAGEG-----EGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGV 75
           ++ E  +A++    ++P G+G     E V L++ I+LLNGV +IVG +IGSGIFV+P GV
Sbjct: 3   DSTEYEVASQPEVETSPLGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGV 62

Query: 76  LKEAGSPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWI 135
           L  + S GL+LV+WA  G+FS+ GALCYAELGTTI KSG  YAY+LE +G   AF++LW 
Sbjct: 63  LIYSASFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWT 122

Query: 136 ELLIIRPSSQYIVALVFATYLLKPLFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATR 195
            LLII P+SQ I+A+ FA Y+++PLFP+C  P  A++L+A  C+ LLT +NC  VK  T 
Sbjct: 123 SLLIIEPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTL 182

Query: 196 VQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDVGNIVLALYSGLFAYG 255
           VQD F  AK+LAL  +I+ G V++G+G  ++ +   SFEG+   VG+I LALYS LF+Y 
Sbjct: 183 VQDIFTYAKVLALIAVIVAGIVRLGQGASTHFEN--SFEGSSFAVGDIALALYSALFSYS 240

Query: 256 GWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDF 315
           GW+ LN+VTEE+ NP RNLPL+I IS+PIVT++Y+LTN+AY+T L    +L+S+AVAV F
Sbjct: 241 GWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTF 300

Query: 316 GNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVP 375
            +   G+ +WIIP+ V LSCFG +N S+  +SRLFFVGSREGHLP  + MIH +  TPVP
Sbjct: 301 ADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVP 360

Query: 376 SLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRHRKPELERPIKVNLAL 435
           SL+F  +M L+Y   +DIF +IN++SF  W  V L+I+G ++LR ++P+  RP+K+++  
Sbjct: 361 SLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFF 420

Query: 436 PVFFILACLFLIAVSFWKTPVECGIGFTIILSGLPVYF--FGVWWKNKPKWLLQGIFSTT 493
           P+ F L  +FL+AV  +   +   IG  I LSGLP YF    V    +P +L + + S T
Sbjct: 421 PIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSAT 480

Query: 494 VLCQKLMQVVPQE 506
              Q L   V  E
Sbjct: 481 RYLQVLCMSVAAE 493


>gi|7657683 solute carrier family 7, (cationic amino acid
           transporter, y+ system) member 11 [Homo sapiens]
          Length = 501

 Score =  467 bits (1202), Expect = e-131
 Identities = 229/476 (48%), Positives = 321/476 (67%), Gaps = 3/476 (0%)

Query: 31  SADGSAPAGEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWA 90
           S     P G+ E V L+R +TLL GV+II+GTIIG+GIF++P GVL+  GS G++L +W 
Sbjct: 26  SLGNKEPPGQ-EKVQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTGSVGMSLTIWT 84

Query: 91  ACGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVAL 150
            CGV S+ GAL YAELGTTI KSGG Y Y+LEV+G LPAF+++W+ELLIIRP++  +++L
Sbjct: 85  VCGVLSLFGALSYAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELLIIRPAATAVISL 144

Query: 151 VFATYLLKPLFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALAL 210
            F  Y+L+P F  C +PE A KL+  + + ++  +N  SV  + R+Q      KL A+ +
Sbjct: 145 AFGRYILEPFFIQCEIPELAIKLITAVGITVVMVLNSMSVSWSARIQIFLTFCKLTAILI 204

Query: 211 IILLGFVQIGKGDVSNLDPNFSFEGTKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINP 270
           II+ G +Q+ KG   N    FS  G    +  + LA Y G++AY GW YLNFVTEE+ NP
Sbjct: 205 IIVPGVMQLIKGQTQNFKDAFS--GRDSSITRLPLAFYYGMYAYAGWFYLNFVTEEVENP 262

Query: 271 YRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVF 330
            + +PLAI IS+ IVT+ YVLTN+AYFTT++ E++L S AVAV F    LG  S  +P+F
Sbjct: 263 EKTIPLAICISMAIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSERLLGNFSLAVPIF 322

Query: 331 VGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFS 390
           V LSCFGS+NG +F  SRLF+V SREGHLP ILSMIH +  TP+P+++    +T++  FS
Sbjct: 323 VALSCFGSMNGGVFAVSRLFYVASREGHLPEILSMIHVRKHTPLPAVIVLHPLTMIMLFS 382

Query: 391 KDIFSVINFFSFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVS 450
            D+ S++NF SF  WL + LA+ G+I+LR++ P++ RP KV L +P  F   CLF++A+S
Sbjct: 383 GDLDSLLNFLSFARWLFIGLAVAGLIYLRYKCPDMHRPFKVPLFIPALFSFTCLFMVALS 442

Query: 451 FWKTPVECGIGFTIILSGLPVYFFGVWWKNKPKWLLQGIFSTTVLCQKLMQVVPQE 506
            +  P   GIGF I L+G+P Y+  + W  KP+W        T   Q +++VVP+E
Sbjct: 443 LYSDPFSTGIGFVITLTGVPAYYLFIIWDKKPRWFRIMSEKITRTLQIILEVVPEE 498


>gi|9790235 solute carrier family 7, member 10 [Homo sapiens]
          Length = 523

 Score =  461 bits (1187), Expect = e-130
 Identities = 235/476 (49%), Positives = 330/476 (69%), Gaps = 5/476 (1%)

Query: 34  GSAPAGEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACG 93
           G+ P G  E V L++ I LL+   II+G IIGSGIF++P GVL+ +GS GLAL VW   G
Sbjct: 25  GTVP-GASERVALKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHSGSVGLALFVWVLGG 83

Query: 94  VFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFA 153
             + +G+LCYAELG  I KSGGDYAY+ E++G L  FL LW  +LI+ P+S  ++++ F+
Sbjct: 84  GVTALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVISMTFS 143

Query: 154 TYLLKPLFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIIL 213
            Y+L+P+FP C  P  A+++++  C++LLT VN  SV+ ATR+QD F   KLLAL+LII 
Sbjct: 144 NYVLQPVFPNCIPPTTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLIIG 203

Query: 214 LGFVQIGKGDVSNLDPN--FSFEGTKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPY 271
           +G +QI +G    L P+  F+F  T   VG++ LA   G FA+ GWN+LN+VTEEM++  
Sbjct: 204 VGLLQIFQGHFEELRPSNAFAFWMTP-SVGHLALAFLQGSFAFSGWNFLNYVTEEMVDAR 262

Query: 272 RNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFV 331
           +NLP AI IS+P+VT VY  TN+AYFT +S +++LSS AVAV FG   LG  SW++PV V
Sbjct: 263 KNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVTFGEKLLGYFSWVMPVSV 322

Query: 332 GLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSK 391
            LS FG +NG LFT SRL F G+REGHLPS+L+MIH +  TP+P+L+  C  T +     
Sbjct: 323 ALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHVRHCTPIPALLVCCGATAVIMLVG 382

Query: 392 DIFSVINFFSFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVSF 451
           D +++IN+ SF N+LC  + I+G++ LR R+P L RPIKVNL +PV +++   FL+  SF
Sbjct: 383 DTYTLINYVSFINYLCYGVTILGLLLLRWRRPALHRPIKVNLLIPVAYLVFWAFLLVFSF 442

Query: 452 WKTPVECGIGFTIILSGLPVYFFGVWWKNKPKWLLQGIFSTTVLCQKLMQVV-PQE 506
              P+ CG+G  IIL+G+P++F GV+W++KPK + +   S T   Q+L  VV PQ+
Sbjct: 443 ISEPMVCGVGVIIILTGVPIFFLGVFWRSKPKCVHRLTESMTHWGQELCFVVYPQD 498


>gi|187423910 solute carrier family 7, member 9 [Homo sapiens]
          Length = 487

 Score =  415 bits (1066), Expect = e-116
 Identities = 214/473 (45%), Positives = 306/473 (64%), Gaps = 5/473 (1%)

Query: 35  SAPAGEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGV 94
           S  + E +  +LQ+ + L++G++IIVGTIIGSGIFV+P  VL    + G  L++WAACGV
Sbjct: 15  SIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGV 74

Query: 95  FSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFAT 154
            + +GALC+AELGT I+KSGG+Y Y++E YG +PA+L  W  L++I+P+S  I+ L F+ 
Sbjct: 75  LATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLSFSE 134

Query: 155 YLLKPLFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILL 214
           Y+  P +  C  P+   K +A   +L ++ VN  SV+  + VQ+ F AAKL+ +A+II+ 
Sbjct: 135 YVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAIIIIS 194

Query: 215 GFVQIGKGDVSNLDPNFSFEGTKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNL 274
           G V + +G+  N D   SFEG +L VG I LA Y+GL+AY GWN LN++TEE+ NPYRNL
Sbjct: 195 GLVLLAQGNTKNFDN--SFEGAQLSVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNL 252

Query: 275 PLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLS 334
           PLAIII +P+VT  Y+L N++YFT ++  ++L S+AVAV FG+  L   SWI+P+FV  S
Sbjct: 253 PLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFS 312

Query: 335 CFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIF 394
             G+ NG+ FT+ RL +V  REGH+  +LS I  + LTP P+++F  ++  +Y    DI 
Sbjct: 313 TIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDIN 372

Query: 395 SVINFFSFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVSFWKT 454
           S++N+FSF  WL   L I+G+I +R  + ELERPIKV + +PV   L  +FL+       
Sbjct: 373 SLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIISK 432

Query: 455 PV-ECGIGFTIILSGLPVYFFGVWWKNKPKWLLQGIFSTTVLCQKLMQVVPQE 506
           P  E       ILSGL  YF  V +K    W  +     T+  Q LM+VVP E
Sbjct: 433 PTWEYLYCVLFILSGLLFYFLFVHYKF--GWAQKISKPITMHLQMLMEVVPPE 483


>gi|7657591 solute carrier family 7, member 9 [Homo sapiens]
          Length = 487

 Score =  415 bits (1066), Expect = e-116
 Identities = 214/473 (45%), Positives = 306/473 (64%), Gaps = 5/473 (1%)

Query: 35  SAPAGEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGV 94
           S  + E +  +LQ+ + L++G++IIVGTIIGSGIFV+P  VL    + G  L++WAACGV
Sbjct: 15  SIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGV 74

Query: 95  FSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFAT 154
            + +GALC+AELGT I+KSGG+Y Y++E YG +PA+L  W  L++I+P+S  I+ L F+ 
Sbjct: 75  LATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLSFSE 134

Query: 155 YLLKPLFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILL 214
           Y+  P +  C  P+   K +A   +L ++ VN  SV+  + VQ+ F AAKL+ +A+II+ 
Sbjct: 135 YVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAIIIIS 194

Query: 215 GFVQIGKGDVSNLDPNFSFEGTKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNL 274
           G V + +G+  N D   SFEG +L VG I LA Y+GL+AY GWN LN++TEE+ NPYRNL
Sbjct: 195 GLVLLAQGNTKNFDN--SFEGAQLSVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNL 252

Query: 275 PLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLS 334
           PLAIII +P+VT  Y+L N++YFT ++  ++L S+AVAV FG+  L   SWI+P+FV  S
Sbjct: 253 PLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFS 312

Query: 335 CFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIF 394
             G+ NG+ FT+ RL +V  REGH+  +LS I  + LTP P+++F  ++  +Y    DI 
Sbjct: 313 TIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDIN 372

Query: 395 SVINFFSFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVSFWKT 454
           S++N+FSF  WL   L I+G+I +R  + ELERPIKV + +PV   L  +FL+       
Sbjct: 373 SLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIISK 432

Query: 455 PV-ECGIGFTIILSGLPVYFFGVWWKNKPKWLLQGIFSTTVLCQKLMQVVPQE 506
           P  E       ILSGL  YF  V +K    W  +     T+  Q LM+VVP E
Sbjct: 433 PTWEYLYCVLFILSGLLFYFLFVHYKF--GWAQKISKPITMHLQMLMEVVPPE 483


>gi|33286430 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 8 isoform b [Homo
           sapiens]
          Length = 332

 Score =  322 bits (826), Expect = 4e-88
 Identities = 153/294 (52%), Positives = 211/294 (71%), Gaps = 1/294 (0%)

Query: 214 LGFVQIGKGDVSNLDPNFSFEG-TKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYR 272
           +G VQI KG+   L+P  +FE   + D+G + LA   G FAYGGWN+LN+VTEE+++PY+
Sbjct: 1   MGIVQICKGEYFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYK 60

Query: 273 NLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFVG 332
           NLP AI IS+P+VT VYV  N+AY T +S +++L+S AVAV FG   LGVM+WI+P+ V 
Sbjct: 61  NLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVA 120

Query: 333 LSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSKD 392
           LS FG VNGSLFTSSRLFF G+REGHLPS+L+MIH +  TP+P+L+FTC+ TLL   + D
Sbjct: 121 LSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSD 180

Query: 393 IFSVINFFSFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVSFW 452
           ++++IN+  F N+L   + + G I LR +KP++ RPIK+NL  P+ ++L   FL+  S W
Sbjct: 181 MYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLW 240

Query: 453 KTPVECGIGFTIILSGLPVYFFGVWWKNKPKWLLQGIFSTTVLCQKLMQVVPQE 506
             PV CGIG  I+L+G+PVYF GV+W++KPK     I   T++ QK+  VV  E
Sbjct: 241 SEPVVCGIGLAIMLTGVPVYFLGVYWQHKPKCFSDFIELLTLVSQKMCVVVYPE 294


>gi|71999149 solute carrier family 7, (cationic amino acid
           transporter, y+ system) member 13 [Homo sapiens]
          Length = 470

 Score =  222 bits (565), Expect = 7e-58
 Identities = 136/449 (30%), Positives = 238/449 (53%), Gaps = 9/449 (2%)

Query: 41  GEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLK-EAGSPGLALVVWAACGVFSIVG 99
           GE + L+R      G + ++  IIG+GIFV+P GVL     + G++L VWA C + ++  
Sbjct: 4   GEKIQLKRVFGYWWGTSFLLINIIGAGIFVSPKGVLAYSCMNVGVSLCVWAGCAILAMTS 63

Query: 100 ALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIV--ALVFATYLL 157
            LC AE+  +   SG  Y ++   +GS  AFL LW  L +    S  +   AL+ A Y +
Sbjct: 64  TLCSAEISISFPCSGAQYYFLKRYFGSTVAFLNLWTSLFL---GSGVVAGQALLLAEYSI 120

Query: 158 KPLFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFV 217
           +P FP+C VP+   K +A   + ++  +    VK  T +Q A +  K+  L+ I L G V
Sbjct: 121 QPFFPSCSVPKLPKKCLALAMLWIVGILTSRGVKEVTWLQIASSVLKVSILSFISLTGVV 180

Query: 218 QIGKGDVSNLDP-NFSFEGTKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPL 276
            + +G   N++    +F+    D+ +++ A++ G FAY G      +  E+  P   +P 
Sbjct: 181 FLIRGKKENVERFQNAFDAELPDISHLIQAIFQGYFAYSGGACFTLIAGELKKPRTTIPK 240

Query: 277 AIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLSCF 336
            I  +LP+VT+VY+L N++Y T L+  ++LSS+AVA+ + +     ++WI+P  +  S F
Sbjct: 241 CIFTALPLVTVVYLLVNISYLTVLTPREILSSDAVAITWADRAFPSLAWIMPFAISTSLF 300

Query: 337 GSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSV 396
            ++  S+F SSR  ++ S+EG LP + + ++    +P  +++    +  L      +  +
Sbjct: 301 SNLLISIFKSSRPIYLASQEGQLPLLFNTLNSH-SSPFTAVLLLVTLGSLAIILTSLIDL 359

Query: 397 INFFSFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVSFWKTP- 455
           IN+  F   L   L +IG++  R+++P L  P KV L+ P+  I+  + L+ +   K+P 
Sbjct: 360 INYIFFTGSLWSILLMIGILRRRYQEPNLSIPYKVFLSFPLATIVIDVGLVVIPLVKSPN 419

Query: 456 VECGIGFTIILSGLPVYFFGVWWKNKPKW 484
           V       ++LSGL  Y   + +K +  W
Sbjct: 420 VHYVYVLLLVLSGLLFYIPLIHFKIRLAW 448


>gi|114326550 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 3 [Homo sapiens]
          Length = 619

 Score =  108 bits (271), Expect = 9e-24
 Identities = 105/411 (25%), Positives = 179/411 (43%), Gaps = 42/411 (10%)

Query: 46  LQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALCYAE 105
           L R ++ L+ VA+ VG+ +G+G++V    V K+   P + ++ +    + S++  LCYAE
Sbjct: 28  LARCLSTLDLVALGVGSTLGAGVYVLAGEVAKDKAGPSI-VICFLVAALSSVLAGLCYAE 86

Query: 106 LGTTISKSGGDYAYMLEVYGSLPAFLKLWIELL--------IIRPSSQYIVALVFATYLL 157
            G  + +SG  Y Y     G L AF   W  +L        + R  S     L+   ++ 
Sbjct: 87  FGARVPRSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNLI-GNHIS 145

Query: 158 KPLFPTCP--VPEEAAK---LVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALII 212
           K L  +    VP   A+     A   VLLLT +       +  V   F    LL L  ++
Sbjct: 146 KTLQGSIALHVPHVLAEYPDFFALGLVLLLTGLLALGASESALVTKVFTGVNLLVLGFVM 205

Query: 213 LLGFVQIGKGDVSN------------LDPNFSFEGTKLDVGNIVLALYSGL--------F 252
           + GFV   KGDV N             + N ++    L  G  V   + G+        +
Sbjct: 206 ISGFV---KGDVHNWKLTEEDYELAMAELNDTYSLGPLGSGGFVPFGFEGILRGAATCFY 262

Query: 253 AYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVA 312
           A+ G++ +    EE  NP R++P+ I+ISL +  L Y   + A    +   Q+     + 
Sbjct: 263 AFVGFDCIATTGEEAQNPQRSIPMGIVISLSVCFLAYFAVSSALTLMMPYYQLQPESPLP 322

Query: 313 VDFGNYHLGVMSWIIPVFVGLSCFGSVN--GSLFTSSRLFFVGSREGHLPSILSMIHPQL 370
             F   ++G       V VG  C  S +  GS+F   R+ +  + +G L  +L+ IH   
Sbjct: 323 EAF--LYIGWAPARYVVAVGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFRVLARIHTGT 380

Query: 371 LTPVPSLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRHR 421
            TP+ + V + ++    AF   +  +++  S    L  +L  I ++ LR++
Sbjct: 381 RTPIIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLLAYSLVSICVLILRYQ 431


>gi|114326544 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 3 [Homo sapiens]
          Length = 619

 Score =  108 bits (271), Expect = 9e-24
 Identities = 105/411 (25%), Positives = 179/411 (43%), Gaps = 42/411 (10%)

Query: 46  LQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALCYAE 105
           L R ++ L+ VA+ VG+ +G+G++V    V K+   P + ++ +    + S++  LCYAE
Sbjct: 28  LARCLSTLDLVALGVGSTLGAGVYVLAGEVAKDKAGPSI-VICFLVAALSSVLAGLCYAE 86

Query: 106 LGTTISKSGGDYAYMLEVYGSLPAFLKLWIELL--------IIRPSSQYIVALVFATYLL 157
            G  + +SG  Y Y     G L AF   W  +L        + R  S     L+   ++ 
Sbjct: 87  FGARVPRSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNLI-GNHIS 145

Query: 158 KPLFPTCP--VPEEAAK---LVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALII 212
           K L  +    VP   A+     A   VLLLT +       +  V   F    LL L  ++
Sbjct: 146 KTLQGSIALHVPHVLAEYPDFFALGLVLLLTGLLALGASESALVTKVFTGVNLLVLGFVM 205

Query: 213 LLGFVQIGKGDVSN------------LDPNFSFEGTKLDVGNIVLALYSGL--------F 252
           + GFV   KGDV N             + N ++    L  G  V   + G+        +
Sbjct: 206 ISGFV---KGDVHNWKLTEEDYELAMAELNDTYSLGPLGSGGFVPFGFEGILRGAATCFY 262

Query: 253 AYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVA 312
           A+ G++ +    EE  NP R++P+ I+ISL +  L Y   + A    +   Q+     + 
Sbjct: 263 AFVGFDCIATTGEEAQNPQRSIPMGIVISLSVCFLAYFAVSSALTLMMPYYQLQPESPLP 322

Query: 313 VDFGNYHLGVMSWIIPVFVGLSCFGSVN--GSLFTSSRLFFVGSREGHLPSILSMIHPQL 370
             F   ++G       V VG  C  S +  GS+F   R+ +  + +G L  +L+ IH   
Sbjct: 323 EAF--LYIGWAPARYVVAVGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFRVLARIHTGT 380

Query: 371 LTPVPSLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRHR 421
            TP+ + V + ++    AF   +  +++  S    L  +L  I ++ LR++
Sbjct: 381 RTPIIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLLAYSLVSICVLILRYQ 431


>gi|110347453 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 4 [Homo sapiens]
          Length = 635

 Score =  108 bits (271), Expect = 9e-24
 Identities = 98/394 (24%), Positives = 175/394 (44%), Gaps = 25/394 (6%)

Query: 45  TLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALCYA 104
           +L+R ++ L+   + VG ++GSG++V    V KE   P + L+ +    V S++ ALCYA
Sbjct: 32  SLRRCLSTLDLTLLGVGGMVGSGLYVLTGAVAKEVAGPAV-LLSFGVAAVASLLAALCYA 90

Query: 105 ELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELL--------IIRPSSQYIVALVFATYL 156
           E G  + ++G  Y +     G L AFL  W  LL        + R  S Y+ ++   ++ 
Sbjct: 91  EFGARVPRTGSAYLFTYVSMGELWAFLIGWNVLLEYIIGGAAVARAWSGYLDSMF--SHS 148

Query: 157 LKPLFPT------CPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALAL 210
           ++    T       P+       +A   +LL +A      + ++ +   F+A  LL +  
Sbjct: 149 IRNFTETHVGSWQVPLLGHYPDFLAAGIILLASAFVSCGARVSSWLNHTFSAISLLVILF 208

Query: 211 IILLGFVQIGKGDVSNLDPNFSFEGTKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINP 270
           I++LGF+     + S  +  F+  G       ++    S  +A+ G++ +   +EE  NP
Sbjct: 209 IVILGFILAQPHNWSADEGGFAPFG----FSGVMAGTASCFYAFVGFDVIAASSEEAQNP 264

Query: 271 YRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVF 330
            R++PLAI ISL I    Y+L +      +    +    A+A  F  Y  G       V 
Sbjct: 265 RRSVPLAIAISLAIAAGAYILVSTVLTLMVPWHSLDPDSALADAF--YQRGYRWAGFIVA 322

Query: 331 VGLSCFGS--VNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYA 388
            G  C  +  +   LF+  R+ +  + +G    + + +HP+   PV   +   ++T   A
Sbjct: 323 AGSICAMNTVLLSLLFSLPRIVYAMAADGLFFQVFAHVHPRTQVPVAGTLAFGLLTAFLA 382

Query: 389 FSKDIFSVINFFSFFNWLCVALAIIGMIWLRHRK 422
              D+ S++ F S    L        +I LR +K
Sbjct: 383 LLLDLESLVQFLSLGTLLAYTFVATSIIVLRFQK 416


>gi|4507047 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 1 [Homo sapiens]
          Length = 629

 Score =  100 bits (250), Expect = 2e-21
 Identities = 105/434 (24%), Positives = 186/434 (42%), Gaps = 47/434 (10%)

Query: 24  EKMLAAKSADGSAPAGEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPG 83
           ++ML  K  D S      E   L R +   + VA+ VG+ +G+G++V    V +E   P 
Sbjct: 11  QQMLRRKVVDCSR-----EETRLSRCLNTFDLVALGVGSTLGAGVYVLAGAVARENAGPA 65

Query: 84  LALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLW---IELLII 140
           + ++ +    + S++  LCY E G  + K+G  Y Y     G L AF+  W   +  +I 
Sbjct: 66  I-VISFLIAALASVLAGLCYGEFGARVPKTGSAYLYSYVTVGELWAFITGWNLILSYIIG 124

Query: 141 RPSSQYIVALVFATYLLKPL------FPTCPVP---EEAAKLVACLCVLLLTAVNCYSVK 191
             S     +  F   + +P+        T   P    E   + A + +L+LT +    VK
Sbjct: 125 TSSVARAWSATFDELIGRPIGEFSRTHMTLNAPGVLAENPDIFAVIIILILTGLLTLGVK 184

Query: 192 AATRVQDAFAAAKLLALALIILLGFVQIGKGDVSN--------------LDPNFSFEGTK 237
            +  V   F    +L L  I++ GFV   KG V N              L  N   +  K
Sbjct: 185 ESAMVNKIFTCINVLVLGFIMVSGFV---KGSVKNWQLTEEDFGNTSGRLCLNNDTKEGK 241

Query: 238 LDVGNIVLALYSGL--------FAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVY 289
             VG  +   +SG+        +A+ G++ +    EE+ NP + +P+ I+ SL I  + Y
Sbjct: 242 PGVGGFMPFGFSGVLSGAATCFYAFVGFDCIATTGEEVKNPQKAIPVGIVASLLICFIAY 301

Query: 290 VLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLSC--FGSVNGSLFTSS 347
              + A  T +     L + +   D    H+G       V VG  C    S+ GS+F   
Sbjct: 302 FGVSAA-LTLMMPYFCLDNNSPLPD-AFKHVGWEGAKYAVAVGSLCALSASLLGSMFPMP 359

Query: 348 RLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFFSFFNWLC 407
           R+ +  + +G L   L+ ++ +  TP+ + + +  +  + AF  D+  +++  S    L 
Sbjct: 360 RVIYAMAEDGLLFKFLANVNDRTKTPIIATLASGAVAAVMAFLFDLKDLVDLMSIGTLLA 419

Query: 408 VALAIIGMIWLRHR 421
            +L    ++ LR++
Sbjct: 420 YSLVAACVLVLRYQ 433


>gi|134304858 solute carrier family 7, member 2 isoform 2 [Homo
           sapiens]
          Length = 658

 Score = 98.2 bits (243), Expect = 2e-20
 Identities = 92/414 (22%), Positives = 178/414 (42%), Gaps = 38/414 (9%)

Query: 42  EGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGAL 101
           E   L R ++ ++ +A+ VG+ +G+G++V    V K    P + +V +    + S++  L
Sbjct: 26  EDTKLCRCLSTMDLIALGVGSTLGAGVYVLAGEVAKADSGPSI-VVSFLIAALASVMAGL 84

Query: 102 CYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELL--IIRPSS---------QYIVAL 150
           CYAE G  + K+G  Y Y     G L AF+  W  +L  +I  SS           +++ 
Sbjct: 85  CYAEFGARVPKTGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDELLSK 144

Query: 151 VFATYLLKPLFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALAL 210
               +L            E     A   +LLL  +  + VK +  V   F A  +L L  
Sbjct: 145 QIGQFLRTYFRMNYTGLAEYPDFFAVCLILLLAGLLSFGVKESAWVNKVFTAVNILVLLF 204

Query: 211 IILLGFVQIGKGDVSNLDPNFSF--------------EGTKL-DVGNIVLALYSG----- 250
           +++ GFV   KG+V+N   +  F               GT +   G  +   ++G     
Sbjct: 205 VMVAGFV---KGNVANWKISEEFLKNISASAREPPSENGTSIYGAGGFMPYGFTGTLAGA 261

Query: 251 ---LFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLS 307
               +A+ G++ +    EE+ NP + +P+ I+ SL +  + Y   + A    +    +  
Sbjct: 262 ATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYLLDE 321

Query: 308 SEAVAVDFGNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIH 367
              + V F     G   +++      +   S+ GS+F   R+ +  + +G L   L+ I+
Sbjct: 322 KSPLPVAFEYVGWGPAKYVVAAGSLCALSTSLLGSIFPMPRVIYAMAEDGLLFKCLAQIN 381

Query: 368 PQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRHR 421
            +  TP+ + + +  +  L AF  D+ ++++  S    +  +L    ++ LR++
Sbjct: 382 SKTKTPIIATLSSGAVAALMAFLFDLKALVDMMSIGTLMAYSLVAACVLILRYQ 435


>gi|109948288 solute carrier family 7, member 2 isoform 1 [Homo
           sapiens]
          Length = 697

 Score = 96.7 bits (239), Expect = 5e-20
 Identities = 94/414 (22%), Positives = 179/414 (43%), Gaps = 39/414 (9%)

Query: 42  EGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGAL 101
           E   L R ++ ++ +A+ VG+ +G+G++V    V K    P + +V +    + S++  L
Sbjct: 66  EDTKLCRCLSTMDLIALGVGSTLGAGVYVLAGEVAKADSGPSI-VVSFLIAALASVMAGL 124

Query: 102 CYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELL--IIRPSS---------QYIVAL 150
           CYAE G  + K+G  Y Y     G L AF+  W  +L  +I  SS           +++ 
Sbjct: 125 CYAEFGARVPKTGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDELLSK 184

Query: 151 VFATYLLKPLFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALAL 210
               +L            E     A   +LLL  +  + VK +  V   F A  +L L  
Sbjct: 185 QIGQFLRTYFRMNYTGLAEYPDFFAVCLILLLAGLLSFGVKESAWVNKVFTAVNILVLLF 244

Query: 211 IILLGFVQIGKGDVSNLDPNFSF--------------EGTKL-DVGNIVLALYSG----- 250
           +++ GFV   KG+V+N   +  F               GT +   G  +   ++G     
Sbjct: 245 VMVAGFV---KGNVANWKISEEFLKNISASAREPPSENGTSIYGAGGFMPYGFTGTLAGA 301

Query: 251 ---LFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLS 307
               +A+ G++ +    EE+ NP + +P+ I+ SL +  + Y   + A    +    +  
Sbjct: 302 ATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYLLDE 361

Query: 308 SEAVAVDFGNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIH 367
              + V F     G   +++      +   S+ GS+F   R+ F  +R+G L   L+ + 
Sbjct: 362 KSPLPVAFEYVGWGPAKYVVAAGSLCALSTSLLGSMFPLPRILFAMARDGLLFRFLARVS 421

Query: 368 PQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRHR 421
            +  +PV + +   V++ L AF  D+ ++++  S    +  +L    ++ LR++
Sbjct: 422 KR-QSPVAATLTAGVISALMAFLFDLKALVDMMSIGTLMAYSLVAACVLILRYQ 474


>gi|181337167 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 14 [Homo sapiens]
          Length = 771

 Score = 85.9 bits (211), Expect = 8e-17
 Identities = 95/407 (23%), Positives = 164/407 (40%), Gaps = 48/407 (11%)

Query: 43  GVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALC 102
           G  L + +T ++ +++ VG+ +G+G++V    V KE   PG+ +V +    V SI+  +C
Sbjct: 46  GTKLAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAGPGV-IVSFIIAAVASILSGVC 104

Query: 103 YAELGTTISK-SGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPLF 161
           YAE G  + K +G  Y Y     G   AF   W  +L      +Y++        L  +F
Sbjct: 105 YAEFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLIL------EYLIGTAAGASALSSMF 158

Query: 162 PTC--------------------PVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFA 201
            +                        E    L+A L  +++T +    VK +    +   
Sbjct: 159 DSLANHTISRWMADSVGTLNGLGKGEESYPDLLALLIAVIVTIIVALGVKNSIGFNNVLN 218

Query: 202 AAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDVG--NIVLALYSGLFAYGGWNY 259
              L     I++ G   I        +  +  EG  L  G   ++    +  +A+ G++ 
Sbjct: 219 VLNLAVWVFIMIAGLFFI--------NGKYWAEGQFLPHGWSGVLQGAATCFYAFIGFDI 270

Query: 260 LNFVTEEMINPYRNLPLAIIISLPIVTLVYV-----LTNLAYFTTLSTEQMLSSEAVAVD 314
           +    EE  NP  ++P AI  SL I    YV     LT +  + T+ TE  L    VA  
Sbjct: 271 IATTGEEAKNPNTSIPYAITASLVICLTAYVSVSVILTLMVPYYTIDTESPLMEMFVAHG 330

Query: 315 FGNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPV 374
           F   +       I    GL+   S+ GSLF   R+ +  + +G L   L+ +     TPV
Sbjct: 331 F---YAAKFVVAIGSVAGLTV--SLLGSLFPMPRVIYAMAGDGLLFRFLAHVSSYTETPV 385

Query: 375 PSLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRHR 421
            + + +  +  L A    +  +I   S    L   L  + ++ LR++
Sbjct: 386 VACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQ 432


>gi|4506975 solute carrier family 12 (sodium/potassium/chloride
           transporters), member 2 [Homo sapiens]
          Length = 1212

 Score = 33.5 bits (75), Expect = 0.47
 Identities = 50/244 (20%), Positives = 95/244 (38%), Gaps = 24/244 (9%)

Query: 63  IIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYMLE 122
           I G  +F+  + ++ +AG     LV+  A  V +I G    A       + GG Y  +  
Sbjct: 299 IWGVMLFIRLSWIVGQAGIGLSVLVIMMATVVTTITGLSTSAIATNGFVRGGGAYYLISR 358

Query: 123 VYGSLPAF---LKLWIELLIIRPSSQYIVALVFATYLLKPLFPTCPVPE-EAAKLVACLC 178
             G  P F   + L          + Y+V        L        + E    +++  + 
Sbjct: 359 SLG--PEFGGAIGLIFAFANAVAVAMYVVGFAETVVELLKEHSILMIDEINDIRIIGAIT 416

Query: 179 VLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIG----------KGDV--SN 226
           V++L  ++   ++   + Q       LLA+   ++  F+ +           K ++   N
Sbjct: 417 VVILLGISVAGMEWEAKAQIVLLVILLLAIGDFVIGTFIPLESKKPKGFFGYKSEIFNEN 476

Query: 227 LDPNFSFEGTKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVT 286
             P+F  E T   V  I     +G+ A  G N    ++ ++ +P   +P   ++++ I T
Sbjct: 477 FGPDFREEETFFSVFAIFFPAATGILA--GAN----ISGDLADPQSAIPKGTLLAILITT 530

Query: 287 LVYV 290
           LVYV
Sbjct: 531 LVYV 534


>gi|41406091 non-imprinted in Prader-Willi/Angelman syndrome 1
           isoform 1 [Homo sapiens]
          Length = 329

 Score = 33.1 bits (74), Expect = 0.61
 Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 2/76 (2%)

Query: 28  AAKSADGSAPAGEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVL--KEAGSPGLA 85
           AA +A  +A AGEG        ++L  GVA++   + GS   +   G++  K  G+  L 
Sbjct: 6   AAAAAAAAAAAGEGARSPSPAAVSLGLGVAVVSSLVNGSTFVLQKKGIVRAKRRGTSYLT 65

Query: 86  LVVWAACGVFSIVGAL 101
            +VW A  +   VG +
Sbjct: 66  DIVWWAGTIAMAVGQI 81


>gi|40354216 sine oculis homeobox homolog 5 [Homo sapiens]
          Length = 739

 Score = 33.1 bits (74), Expect = 0.61
 Identities = 17/40 (42%), Positives = 24/40 (60%)

Query: 4  AGPKRRALAAPAAEEKEEAREKMLAAKSADGSAPAGEGEG 43
          AG +  A AA   EE+EEAR+ +   ++A+G A A  G G
Sbjct: 14 AGGEAVAAAAATEEEEEEARQLLQTLQAAEGEAAAAAGAG 53


>gi|110224458 solute carrier family 12, member 6 isoform e [Homo
           sapiens]
          Length = 1135

 Score = 32.7 bits (73), Expect = 0.80
 Identities = 41/191 (21%), Positives = 79/191 (41%), Gaps = 14/191 (7%)

Query: 272 RNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFV 331
           +++P+  I+++   + VY L+N+  F       +L  +      GN  +G +SW  P  +
Sbjct: 499 KSIPIGTILAILTTSFVY-LSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVI 557

Query: 332 GLSCFGSVNG----SLFTSSRLFFVGSREGHLPSILSMIHPQLL-TPVPSLVFTCVMTLL 386
            +  F S  G    SL  + RL    +++  +P +    H +    P  +L+ T  +  L
Sbjct: 558 VIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAEL 617

Query: 387 YAFSKDIFSVINFFSFFNWLC-----VALAIIGMIWLRHRKPELERPIKVNLALPVFFIL 441
                 +  V    S F  +C     +A A+  ++   + +P        + AL    + 
Sbjct: 618 GILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFR---YYHWALSFMGMS 674

Query: 442 ACLFLIAVSFW 452
            CL L+ +S W
Sbjct: 675 ICLALMFISSW 685


>gi|110224456 solute carrier family 12, member 6 isoform d [Homo
           sapiens]
          Length = 1141

 Score = 32.7 bits (73), Expect = 0.80
 Identities = 41/191 (21%), Positives = 79/191 (41%), Gaps = 14/191 (7%)

Query: 272 RNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFV 331
           +++P+  I+++   + VY L+N+  F       +L  +      GN  +G +SW  P  +
Sbjct: 505 KSIPIGTILAILTTSFVY-LSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVI 563

Query: 332 GLSCFGSVNG----SLFTSSRLFFVGSREGHLPSILSMIHPQLL-TPVPSLVFTCVMTLL 386
            +  F S  G    SL  + RL    +++  +P +    H +    P  +L+ T  +  L
Sbjct: 564 VIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAEL 623

Query: 387 YAFSKDIFSVINFFSFFNWLC-----VALAIIGMIWLRHRKPELERPIKVNLALPVFFIL 441
                 +  V    S F  +C     +A A+  ++   + +P        + AL    + 
Sbjct: 624 GILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFR---YYHWALSFMGMS 680

Query: 442 ACLFLIAVSFW 452
            CL L+ +S W
Sbjct: 681 ICLALMFISSW 691


>gi|110224454 solute carrier family 12, member 6 isoform c [Homo
           sapiens]
          Length = 1091

 Score = 32.7 bits (73), Expect = 0.80
 Identities = 41/191 (21%), Positives = 79/191 (41%), Gaps = 14/191 (7%)

Query: 272 RNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFV 331
           +++P+  I+++   + VY L+N+  F       +L  +      GN  +G +SW  P  +
Sbjct: 455 KSIPIGTILAILTTSFVY-LSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVI 513

Query: 332 GLSCFGSVNG----SLFTSSRLFFVGSREGHLPSILSMIHPQLL-TPVPSLVFTCVMTLL 386
            +  F S  G    SL  + RL    +++  +P +    H +    P  +L+ T  +  L
Sbjct: 514 VIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAEL 573

Query: 387 YAFSKDIFSVINFFSFFNWLC-----VALAIIGMIWLRHRKPELERPIKVNLALPVFFIL 441
                 +  V    S F  +C     +A A+  ++   + +P        + AL    + 
Sbjct: 574 GILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFR---YYHWALSFMGMS 630

Query: 442 ACLFLIAVSFW 452
            CL L+ +S W
Sbjct: 631 ICLALMFISSW 641


>gi|110224452 solute carrier family 12, member 6 isoform c [Homo
           sapiens]
          Length = 1091

 Score = 32.7 bits (73), Expect = 0.80
 Identities = 41/191 (21%), Positives = 79/191 (41%), Gaps = 14/191 (7%)

Query: 272 RNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFV 331
           +++P+  I+++   + VY L+N+  F       +L  +      GN  +G +SW  P  +
Sbjct: 455 KSIPIGTILAILTTSFVY-LSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVI 513

Query: 332 GLSCFGSVNG----SLFTSSRLFFVGSREGHLPSILSMIHPQLL-TPVPSLVFTCVMTLL 386
            +  F S  G    SL  + RL    +++  +P +    H +    P  +L+ T  +  L
Sbjct: 514 VIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAEL 573

Query: 387 YAFSKDIFSVINFFSFFNWLC-----VALAIIGMIWLRHRKPELERPIKVNLALPVFFIL 441
                 +  V    S F  +C     +A A+  ++   + +P        + AL    + 
Sbjct: 574 GILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFR---YYHWALSFMGMS 630

Query: 442 ACLFLIAVSFW 452
            CL L+ +S W
Sbjct: 631 ICLALMFISSW 641


>gi|4826780 solute carrier family 12, member 6 isoform b [Homo
           sapiens]
          Length = 1099

 Score = 32.7 bits (73), Expect = 0.80
 Identities = 41/191 (21%), Positives = 79/191 (41%), Gaps = 14/191 (7%)

Query: 272 RNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFV 331
           +++P+  I+++   + VY L+N+  F       +L  +      GN  +G +SW  P  +
Sbjct: 463 KSIPIGTILAILTTSFVY-LSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVI 521

Query: 332 GLSCFGSVNG----SLFTSSRLFFVGSREGHLPSILSMIHPQLL-TPVPSLVFTCVMTLL 386
            +  F S  G    SL  + RL    +++  +P +    H +    P  +L+ T  +  L
Sbjct: 522 VIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAEL 581

Query: 387 YAFSKDIFSVINFFSFFNWLC-----VALAIIGMIWLRHRKPELERPIKVNLALPVFFIL 441
                 +  V    S F  +C     +A A+  ++   + +P        + AL    + 
Sbjct: 582 GILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFR---YYHWALSFMGMS 638

Query: 442 ACLFLIAVSFW 452
            CL L+ +S W
Sbjct: 639 ICLALMFISSW 649


>gi|110224449 solute carrier family 12, member 6 isoform a [Homo
           sapiens]
          Length = 1150

 Score = 32.7 bits (73), Expect = 0.80
 Identities = 41/191 (21%), Positives = 79/191 (41%), Gaps = 14/191 (7%)

Query: 272 RNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFV 331
           +++P+  I+++   + VY L+N+  F       +L  +      GN  +G +SW  P  +
Sbjct: 514 KSIPIGTILAILTTSFVY-LSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVI 572

Query: 332 GLSCFGSVNG----SLFTSSRLFFVGSREGHLPSILSMIHPQLL-TPVPSLVFTCVMTLL 386
            +  F S  G    SL  + RL    +++  +P +    H +    P  +L+ T  +  L
Sbjct: 573 VIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAEL 632

Query: 387 YAFSKDIFSVINFFSFFNWLC-----VALAIIGMIWLRHRKPELERPIKVNLALPVFFIL 441
                 +  V    S F  +C     +A A+  ++   + +P        + AL    + 
Sbjct: 633 GILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFR---YYHWALSFMGMS 689

Query: 442 ACLFLIAVSFW 452
            CL L+ +S W
Sbjct: 690 ICLALMFISSW 700


>gi|16418463 MAS1 oncogene-like [Homo sapiens]
          Length = 378

 Score = 32.0 bits (71), Expect = 1.4
 Identities = 36/148 (24%), Positives = 65/148 (43%), Gaps = 18/148 (12%)

Query: 335 CFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLL-----YAF 389
           C   +NG++F    L   G+   ++  IL ++   ++    S V    +TLL       F
Sbjct: 88  CGVLLNGTVFW---LLCCGATNPYMVYILHLVAADVIYLCCSAVGFLQVTLLTYHGVVFF 144

Query: 390 SKDIFSVINFFSFFNWLCVALAI--------IGMIWLRHRKPELERPIKVNLALPVFFIL 441
             D  ++++ FSF   LC+ +AI        +  IW R  +P+    +   L   + F +
Sbjct: 145 IPDFLAILSPFSFEVCLCLLVAISTERCVCVLFPIWYRCHRPKYTSNVVCTLIWGLPFCI 204

Query: 442 ACLFLIAVSFWKTPVECGIGFTIILSGL 469
             +  + +++WK    C I   + LSGL
Sbjct: 205 NIVKSLFLTYWKHVKACVI--FLKLSGL 230


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.141    0.435 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,564,508
Number of Sequences: 37866
Number of extensions: 814899
Number of successful extensions: 2999
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 2899
Number of HSP's gapped (non-prelim): 59
length of query: 507
length of database: 18,247,518
effective HSP length: 107
effective length of query: 400
effective length of database: 14,195,856
effective search space: 5678342400
effective search space used: 5678342400
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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