BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|71979932 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 [Homo sapiens] (507 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|71979932 solute carrier family 7 (cationic amino acid transpo... 1006 0.0 gi|33286428 solute carrier family 7 (cationic amino acid transpo... 538 e-153 gi|115648063 solute carrier family 7 (cationic amino acid transp... 484 e-137 gi|115648022 solute carrier family 7 (cationic amino acid transp... 484 e-137 gi|186910308 solute carrier family 7 member 7 [Homo sapiens] 475 e-134 gi|186910306 solute carrier family 7 member 7 [Homo sapiens] 475 e-134 gi|186910304 solute carrier family 7 member 7 [Homo sapiens] 475 e-134 gi|7657683 solute carrier family 7, (cationic amino acid transpo... 467 e-131 gi|9790235 solute carrier family 7, member 10 [Homo sapiens] 461 e-130 gi|187423910 solute carrier family 7, member 9 [Homo sapiens] 415 e-116 gi|7657591 solute carrier family 7, member 9 [Homo sapiens] 415 e-116 gi|33286430 solute carrier family 7 (cationic amino acid transpo... 322 4e-88 gi|71999149 solute carrier family 7, (cationic amino acid transp... 222 7e-58 gi|114326550 solute carrier family 7 (cationic amino acid transp... 108 9e-24 gi|114326544 solute carrier family 7 (cationic amino acid transp... 108 9e-24 gi|110347453 solute carrier family 7 (cationic amino acid transp... 108 9e-24 gi|4507047 solute carrier family 7 (cationic amino acid transpor... 100 2e-21 gi|134304858 solute carrier family 7, member 2 isoform 2 [Homo s... 98 2e-20 gi|109948288 solute carrier family 7, member 2 isoform 1 [Homo s... 97 5e-20 gi|181337167 solute carrier family 7 (cationic amino acid transp... 86 8e-17 gi|4506975 solute carrier family 12 (sodium/potassium/chloride t... 33 0.47 gi|41406091 non-imprinted in Prader-Willi/Angelman syndrome 1 is... 33 0.61 gi|40354216 sine oculis homeobox homolog 5 [Homo sapiens] 33 0.61 gi|110224458 solute carrier family 12, member 6 isoform e [Homo ... 33 0.80 gi|110224456 solute carrier family 12, member 6 isoform d [Homo ... 33 0.80 gi|110224454 solute carrier family 12, member 6 isoform c [Homo ... 33 0.80 gi|110224452 solute carrier family 12, member 6 isoform c [Homo ... 33 0.80 gi|4826780 solute carrier family 12, member 6 isoform b [Homo sa... 33 0.80 gi|110224449 solute carrier family 12, member 6 isoform a [Homo ... 33 0.80 gi|16418463 MAS1 oncogene-like [Homo sapiens] 32 1.4 >gi|71979932 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 [Homo sapiens] Length = 507 Score = 1006 bits (2602), Expect = 0.0 Identities = 507/507 (100%), Positives = 507/507 (100%) Query: 1 MAGAGPKRRALAAPAAEEKEEAREKMLAAKSADGSAPAGEGEGVTLQRNITLLNGVAIIV 60 MAGAGPKRRALAAPAAEEKEEAREKMLAAKSADGSAPAGEGEGVTLQRNITLLNGVAIIV Sbjct: 1 MAGAGPKRRALAAPAAEEKEEAREKMLAAKSADGSAPAGEGEGVTLQRNITLLNGVAIIV 60 Query: 61 GTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYM 120 GTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYM Sbjct: 61 GTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYM 120 Query: 121 LEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPLFPTCPVPEEAAKLVACLCVL 180 LEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPLFPTCPVPEEAAKLVACLCVL Sbjct: 121 LEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPLFPTCPVPEEAAKLVACLCVL 180 Query: 181 LLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDV 240 LLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDV Sbjct: 181 LLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDV 240 Query: 241 GNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTL 300 GNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTL Sbjct: 241 GNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTL 300 Query: 301 STEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLP 360 STEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLP Sbjct: 301 STEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLP 360 Query: 361 SILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRH 420 SILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRH Sbjct: 361 SILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRH 420 Query: 421 RKPELERPIKVNLALPVFFILACLFLIAVSFWKTPVECGIGFTIILSGLPVYFFGVWWKN 480 RKPELERPIKVNLALPVFFILACLFLIAVSFWKTPVECGIGFTIILSGLPVYFFGVWWKN Sbjct: 421 RKPELERPIKVNLALPVFFILACLFLIAVSFWKTPVECGIGFTIILSGLPVYFFGVWWKN 480 Query: 481 KPKWLLQGIFSTTVLCQKLMQVVPQET 507 KPKWLLQGIFSTTVLCQKLMQVVPQET Sbjct: 481 KPKWLLQGIFSTTVLCQKLMQVVPQET 507 >gi|33286428 solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 isoform a [Homo sapiens] Length = 535 Score = 538 bits (1385), Expect = e-153 Identities = 263/493 (53%), Positives = 354/493 (71%), Gaps = 2/493 (0%) Query: 16 AEEKEEAREKMLAAKSADGSAPAGEGEG-VTLQRNITLLNGVAIIVGTIIGSGIFVTPTG 74 A + +K +D S AG G G V L++ I L++ IIVG IIGSGIFV+P G Sbjct: 5 ARHRNNTEKKHPGGGESDASPEAGSGGGGVALKKEIGLVSACGIIVGNIIGSGIFVSPKG 64 Query: 75 VLKEAGSPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLW 134 VL+ AGS GLAL+VW G ++VGALCYAELG TI KSGGDY+Y+ +++G L FL+LW Sbjct: 65 VLENAGSVGLALIVWIVTGFITVVGALCYAELGVTIPKSGGDYSYVKDIFGGLAGFLRLW 124 Query: 135 IELLIIRPSSQYIVALVFATYLLKPLFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAAT 194 I +L+I P++Q ++AL F+ Y+L+PLFPTC PE +L+A +C+LLLT VNC SV+ AT Sbjct: 125 IAVLVIYPTNQAVIALTFSNYVLQPLFPTCFPPESGLRLLAAICLLLLTWVNCSSVRWAT 184 Query: 195 RVQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEG-TKLDVGNIVLALYSGLFA 253 RVQD F A KLLALALII++G VQI KG+ L+P +FE + D+G + LA G FA Sbjct: 185 RVQDIFTAGKLLALALIIIMGIVQICKGEYFWLEPKNAFENFQEPDIGLVALAFLQGSFA 244 Query: 254 YGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAV 313 YGGWN+LN+VTEE+++PY+NLP AI IS+P+VT VYV N+AY T +S +++L+S AVAV Sbjct: 245 YGGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAV 304 Query: 314 DFGNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTP 373 FG LGVM+WI+P+ V LS FG VNGSLFTSSRLFF G+REGHLPS+L+MIH + TP Sbjct: 305 TFGEKLLGVMAWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTP 364 Query: 374 VPSLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRHRKPELERPIKVNL 433 +P+L+FTC+ TLL + D++++IN+ F N+L + + G I LR +KP++ RPIK+NL Sbjct: 365 IPALLFTCISTLLMLVTSDMYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINL 424 Query: 434 ALPVFFILACLFLIAVSFWKTPVECGIGFTIILSGLPVYFFGVWWKNKPKWLLQGIFSTT 493 P+ ++L FL+ S W PV CGIG I+L+G+PVYF GV+W++KPK I T Sbjct: 425 LFPIIYLLFWAFLLVFSLWSEPVVCGIGLAIMLTGVPVYFLGVYWQHKPKCFSDFIELLT 484 Query: 494 VLCQKLMQVVPQE 506 ++ QK+ VV E Sbjct: 485 LVSQKMCVVVYPE 497 >gi|115648063 solute carrier family 7 (cationic amino acid transporter, y+ system), member 6 [Homo sapiens] Length = 515 Score = 484 bits (1246), Expect = e-137 Identities = 230/443 (51%), Positives = 320/443 (72%), Gaps = 2/443 (0%) Query: 35 SAPAGEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGV 94 S P E + L++ I+LLNGV+++VG +IGSGIFV+P GVL S G++L+VWA G+ Sbjct: 30 SPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASYGMSLIVWAIGGL 89 Query: 95 FSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFAT 154 FS+VGALCYAELGTTI+KSG YAY+LE +G AF++LW+ LL++ P+ Q I+A+ FA Sbjct: 90 FSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEPTGQAIIAITFAN 149 Query: 155 YLLKPLFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILL 214 Y+++P FP+C P A +L+A C+ LLT VNC VK TRVQD F AK++AL II++ Sbjct: 150 YIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTFTYAKVVALIAIIVM 209 Query: 215 GFVQIGKGDVSNLDPNFSFEGTKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNL 274 G V++ +G + +FEG+ D+GN+ LALYS LF+Y GW+ LNFVTEE+ NP RNL Sbjct: 210 GLVKLCQGHSEHFQD--AFEGSSWDMGNLSLALYSALFSYSGWDTLNFVTEEIKNPERNL 267 Query: 275 PLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLS 334 PLAI IS+PIVTL+Y+LTN+AY+T L+ +LSS+AVAV F + G+ SW IP+ V LS Sbjct: 268 PLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGMFSWTIPIAVALS 327 Query: 335 CFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIF 394 CFG +N S+F SSRLFFVGSREGHLP +LSMIH + TP+P+L+F C M L+Y +D+F Sbjct: 328 CFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCTMALIYLIVEDVF 387 Query: 395 SVINFFSFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVSFWKT 454 +IN+FSF W V L+++G ++LR ++P+ RP+K+++ P+ F + +FL+ V + Sbjct: 388 QLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCICSVFLVIVPLFTD 447 Query: 455 PVECGIGFTIILSGLPVYFFGVW 477 + IG I LSG+P YF GV+ Sbjct: 448 TINSLIGIGIALSGVPFYFMGVY 470 >gi|115648022 solute carrier family 7 (cationic amino acid transporter, y+ system), member 6 [Homo sapiens] Length = 515 Score = 484 bits (1246), Expect = e-137 Identities = 230/443 (51%), Positives = 320/443 (72%), Gaps = 2/443 (0%) Query: 35 SAPAGEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGV 94 S P E + L++ I+LLNGV+++VG +IGSGIFV+P GVL S G++L+VWA G+ Sbjct: 30 SPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASYGMSLIVWAIGGL 89 Query: 95 FSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFAT 154 FS+VGALCYAELGTTI+KSG YAY+LE +G AF++LW+ LL++ P+ Q I+A+ FA Sbjct: 90 FSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEPTGQAIIAITFAN 149 Query: 155 YLLKPLFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILL 214 Y+++P FP+C P A +L+A C+ LLT VNC VK TRVQD F AK++AL II++ Sbjct: 150 YIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTFTYAKVVALIAIIVM 209 Query: 215 GFVQIGKGDVSNLDPNFSFEGTKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNL 274 G V++ +G + +FEG+ D+GN+ LALYS LF+Y GW+ LNFVTEE+ NP RNL Sbjct: 210 GLVKLCQGHSEHFQD--AFEGSSWDMGNLSLALYSALFSYSGWDTLNFVTEEIKNPERNL 267 Query: 275 PLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLS 334 PLAI IS+PIVTL+Y+LTN+AY+T L+ +LSS+AVAV F + G+ SW IP+ V LS Sbjct: 268 PLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGMFSWTIPIAVALS 327 Query: 335 CFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIF 394 CFG +N S+F SSRLFFVGSREGHLP +LSMIH + TP+P+L+F C M L+Y +D+F Sbjct: 328 CFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCTMALIYLIVEDVF 387 Query: 395 SVINFFSFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVSFWKT 454 +IN+FSF W V L+++G ++LR ++P+ RP+K+++ P+ F + +FL+ V + Sbjct: 388 QLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCICSVFLVIVPLFTD 447 Query: 455 PVECGIGFTIILSGLPVYFFGVW 477 + IG I LSG+P YF GV+ Sbjct: 448 TINSLIGIGIALSGVPFYFMGVY 470 >gi|186910308 solute carrier family 7 member 7 [Homo sapiens] Length = 511 Score = 475 bits (1223), Expect = e-134 Identities = 243/493 (49%), Positives = 339/493 (68%), Gaps = 9/493 (1%) Query: 21 EAREKMLAAKSADGSAPAGEG-----EGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGV 75 ++ E +A++ ++P G+G E V L++ I+LLNGV +IVG +IGSGIFV+P GV Sbjct: 3 DSTEYEVASQPEVETSPLGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGV 62 Query: 76 LKEAGSPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWI 135 L + S GL+LV+WA G+FS+ GALCYAELGTTI KSG YAY+LE +G AF++LW Sbjct: 63 LIYSASFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWT 122 Query: 136 ELLIIRPSSQYIVALVFATYLLKPLFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATR 195 LLII P+SQ I+A+ FA Y+++PLFP+C P A++L+A C+ LLT +NC VK T Sbjct: 123 SLLIIEPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTL 182 Query: 196 VQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDVGNIVLALYSGLFAYG 255 VQD F AK+LAL +I+ G V++G+G ++ + SFEG+ VG+I LALYS LF+Y Sbjct: 183 VQDIFTYAKVLALIAVIVAGIVRLGQGASTHFEN--SFEGSSFAVGDIALALYSALFSYS 240 Query: 256 GWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDF 315 GW+ LN+VTEE+ NP RNLPL+I IS+PIVT++Y+LTN+AY+T L +L+S+AVAV F Sbjct: 241 GWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTF 300 Query: 316 GNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVP 375 + G+ +WIIP+ V LSCFG +N S+ +SRLFFVGSREGHLP + MIH + TPVP Sbjct: 301 ADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVP 360 Query: 376 SLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRHRKPELERPIKVNLAL 435 SL+F +M L+Y +DIF +IN++SF W V L+I+G ++LR ++P+ RP+K+++ Sbjct: 361 SLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFF 420 Query: 436 PVFFILACLFLIAVSFWKTPVECGIGFTIILSGLPVYF--FGVWWKNKPKWLLQGIFSTT 493 P+ F L +FL+AV + + IG I LSGLP YF V +P +L + + S T Sbjct: 421 PIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSAT 480 Query: 494 VLCQKLMQVVPQE 506 Q L V E Sbjct: 481 RYLQVLCMSVAAE 493 >gi|186910306 solute carrier family 7 member 7 [Homo sapiens] Length = 511 Score = 475 bits (1223), Expect = e-134 Identities = 243/493 (49%), Positives = 339/493 (68%), Gaps = 9/493 (1%) Query: 21 EAREKMLAAKSADGSAPAGEG-----EGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGV 75 ++ E +A++ ++P G+G E V L++ I+LLNGV +IVG +IGSGIFV+P GV Sbjct: 3 DSTEYEVASQPEVETSPLGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGV 62 Query: 76 LKEAGSPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWI 135 L + S GL+LV+WA G+FS+ GALCYAELGTTI KSG YAY+LE +G AF++LW Sbjct: 63 LIYSASFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWT 122 Query: 136 ELLIIRPSSQYIVALVFATYLLKPLFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATR 195 LLII P+SQ I+A+ FA Y+++PLFP+C P A++L+A C+ LLT +NC VK T Sbjct: 123 SLLIIEPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTL 182 Query: 196 VQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDVGNIVLALYSGLFAYG 255 VQD F AK+LAL +I+ G V++G+G ++ + SFEG+ VG+I LALYS LF+Y Sbjct: 183 VQDIFTYAKVLALIAVIVAGIVRLGQGASTHFEN--SFEGSSFAVGDIALALYSALFSYS 240 Query: 256 GWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDF 315 GW+ LN+VTEE+ NP RNLPL+I IS+PIVT++Y+LTN+AY+T L +L+S+AVAV F Sbjct: 241 GWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTF 300 Query: 316 GNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVP 375 + G+ +WIIP+ V LSCFG +N S+ +SRLFFVGSREGHLP + MIH + TPVP Sbjct: 301 ADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVP 360 Query: 376 SLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRHRKPELERPIKVNLAL 435 SL+F +M L+Y +DIF +IN++SF W V L+I+G ++LR ++P+ RP+K+++ Sbjct: 361 SLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFF 420 Query: 436 PVFFILACLFLIAVSFWKTPVECGIGFTIILSGLPVYF--FGVWWKNKPKWLLQGIFSTT 493 P+ F L +FL+AV + + IG I LSGLP YF V +P +L + + S T Sbjct: 421 PIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSAT 480 Query: 494 VLCQKLMQVVPQE 506 Q L V E Sbjct: 481 RYLQVLCMSVAAE 493 >gi|186910304 solute carrier family 7 member 7 [Homo sapiens] Length = 511 Score = 475 bits (1223), Expect = e-134 Identities = 243/493 (49%), Positives = 339/493 (68%), Gaps = 9/493 (1%) Query: 21 EAREKMLAAKSADGSAPAGEG-----EGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGV 75 ++ E +A++ ++P G+G E V L++ I+LLNGV +IVG +IGSGIFV+P GV Sbjct: 3 DSTEYEVASQPEVETSPLGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGV 62 Query: 76 LKEAGSPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWI 135 L + S GL+LV+WA G+FS+ GALCYAELGTTI KSG YAY+LE +G AF++LW Sbjct: 63 LIYSASFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWT 122 Query: 136 ELLIIRPSSQYIVALVFATYLLKPLFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATR 195 LLII P+SQ I+A+ FA Y+++PLFP+C P A++L+A C+ LLT +NC VK T Sbjct: 123 SLLIIEPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTL 182 Query: 196 VQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDVGNIVLALYSGLFAYG 255 VQD F AK+LAL +I+ G V++G+G ++ + SFEG+ VG+I LALYS LF+Y Sbjct: 183 VQDIFTYAKVLALIAVIVAGIVRLGQGASTHFEN--SFEGSSFAVGDIALALYSALFSYS 240 Query: 256 GWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDF 315 GW+ LN+VTEE+ NP RNLPL+I IS+PIVT++Y+LTN+AY+T L +L+S+AVAV F Sbjct: 241 GWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTF 300 Query: 316 GNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVP 375 + G+ +WIIP+ V LSCFG +N S+ +SRLFFVGSREGHLP + MIH + TPVP Sbjct: 301 ADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVP 360 Query: 376 SLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRHRKPELERPIKVNLAL 435 SL+F +M L+Y +DIF +IN++SF W V L+I+G ++LR ++P+ RP+K+++ Sbjct: 361 SLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFF 420 Query: 436 PVFFILACLFLIAVSFWKTPVECGIGFTIILSGLPVYF--FGVWWKNKPKWLLQGIFSTT 493 P+ F L +FL+AV + + IG I LSGLP YF V +P +L + + S T Sbjct: 421 PIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSAT 480 Query: 494 VLCQKLMQVVPQE 506 Q L V E Sbjct: 481 RYLQVLCMSVAAE 493 >gi|7657683 solute carrier family 7, (cationic amino acid transporter, y+ system) member 11 [Homo sapiens] Length = 501 Score = 467 bits (1202), Expect = e-131 Identities = 229/476 (48%), Positives = 321/476 (67%), Gaps = 3/476 (0%) Query: 31 SADGSAPAGEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWA 90 S P G+ E V L+R +TLL GV+II+GTIIG+GIF++P GVL+ GS G++L +W Sbjct: 26 SLGNKEPPGQ-EKVQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTGSVGMSLTIWT 84 Query: 91 ACGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVAL 150 CGV S+ GAL YAELGTTI KSGG Y Y+LEV+G LPAF+++W+ELLIIRP++ +++L Sbjct: 85 VCGVLSLFGALSYAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELLIIRPAATAVISL 144 Query: 151 VFATYLLKPLFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALAL 210 F Y+L+P F C +PE A KL+ + + ++ +N SV + R+Q KL A+ + Sbjct: 145 AFGRYILEPFFIQCEIPELAIKLITAVGITVVMVLNSMSVSWSARIQIFLTFCKLTAILI 204 Query: 211 IILLGFVQIGKGDVSNLDPNFSFEGTKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINP 270 II+ G +Q+ KG N FS G + + LA Y G++AY GW YLNFVTEE+ NP Sbjct: 205 IIVPGVMQLIKGQTQNFKDAFS--GRDSSITRLPLAFYYGMYAYAGWFYLNFVTEEVENP 262 Query: 271 YRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVF 330 + +PLAI IS+ IVT+ YVLTN+AYFTT++ E++L S AVAV F LG S +P+F Sbjct: 263 EKTIPLAICISMAIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSERLLGNFSLAVPIF 322 Query: 331 VGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFS 390 V LSCFGS+NG +F SRLF+V SREGHLP ILSMIH + TP+P+++ +T++ FS Sbjct: 323 VALSCFGSMNGGVFAVSRLFYVASREGHLPEILSMIHVRKHTPLPAVIVLHPLTMIMLFS 382 Query: 391 KDIFSVINFFSFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVS 450 D+ S++NF SF WL + LA+ G+I+LR++ P++ RP KV L +P F CLF++A+S Sbjct: 383 GDLDSLLNFLSFARWLFIGLAVAGLIYLRYKCPDMHRPFKVPLFIPALFSFTCLFMVALS 442 Query: 451 FWKTPVECGIGFTIILSGLPVYFFGVWWKNKPKWLLQGIFSTTVLCQKLMQVVPQE 506 + P GIGF I L+G+P Y+ + W KP+W T Q +++VVP+E Sbjct: 443 LYSDPFSTGIGFVITLTGVPAYYLFIIWDKKPRWFRIMSEKITRTLQIILEVVPEE 498 >gi|9790235 solute carrier family 7, member 10 [Homo sapiens] Length = 523 Score = 461 bits (1187), Expect = e-130 Identities = 235/476 (49%), Positives = 330/476 (69%), Gaps = 5/476 (1%) Query: 34 GSAPAGEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACG 93 G+ P G E V L++ I LL+ II+G IIGSGIF++P GVL+ +GS GLAL VW G Sbjct: 25 GTVP-GASERVALKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHSGSVGLALFVWVLGG 83 Query: 94 VFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFA 153 + +G+LCYAELG I KSGGDYAY+ E++G L FL LW +LI+ P+S ++++ F+ Sbjct: 84 GVTALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVISMTFS 143 Query: 154 TYLLKPLFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIIL 213 Y+L+P+FP C P A+++++ C++LLT VN SV+ ATR+QD F KLLAL+LII Sbjct: 144 NYVLQPVFPNCIPPTTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLIIG 203 Query: 214 LGFVQIGKGDVSNLDPN--FSFEGTKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPY 271 +G +QI +G L P+ F+F T VG++ LA G FA+ GWN+LN+VTEEM++ Sbjct: 204 VGLLQIFQGHFEELRPSNAFAFWMTP-SVGHLALAFLQGSFAFSGWNFLNYVTEEMVDAR 262 Query: 272 RNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFV 331 +NLP AI IS+P+VT VY TN+AYFT +S +++LSS AVAV FG LG SW++PV V Sbjct: 263 KNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVTFGEKLLGYFSWVMPVSV 322 Query: 332 GLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSK 391 LS FG +NG LFT SRL F G+REGHLPS+L+MIH + TP+P+L+ C T + Sbjct: 323 ALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHVRHCTPIPALLVCCGATAVIMLVG 382 Query: 392 DIFSVINFFSFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVSF 451 D +++IN+ SF N+LC + I+G++ LR R+P L RPIKVNL +PV +++ FL+ SF Sbjct: 383 DTYTLINYVSFINYLCYGVTILGLLLLRWRRPALHRPIKVNLLIPVAYLVFWAFLLVFSF 442 Query: 452 WKTPVECGIGFTIILSGLPVYFFGVWWKNKPKWLLQGIFSTTVLCQKLMQVV-PQE 506 P+ CG+G IIL+G+P++F GV+W++KPK + + S T Q+L VV PQ+ Sbjct: 443 ISEPMVCGVGVIIILTGVPIFFLGVFWRSKPKCVHRLTESMTHWGQELCFVVYPQD 498 >gi|187423910 solute carrier family 7, member 9 [Homo sapiens] Length = 487 Score = 415 bits (1066), Expect = e-116 Identities = 214/473 (45%), Positives = 306/473 (64%), Gaps = 5/473 (1%) Query: 35 SAPAGEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGV 94 S + E + +LQ+ + L++G++IIVGTIIGSGIFV+P VL + G L++WAACGV Sbjct: 15 SIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGV 74 Query: 95 FSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFAT 154 + +GALC+AELGT I+KSGG+Y Y++E YG +PA+L W L++I+P+S I+ L F+ Sbjct: 75 LATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLSFSE 134 Query: 155 YLLKPLFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILL 214 Y+ P + C P+ K +A +L ++ VN SV+ + VQ+ F AAKL+ +A+II+ Sbjct: 135 YVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAIIIIS 194 Query: 215 GFVQIGKGDVSNLDPNFSFEGTKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNL 274 G V + +G+ N D SFEG +L VG I LA Y+GL+AY GWN LN++TEE+ NPYRNL Sbjct: 195 GLVLLAQGNTKNFDN--SFEGAQLSVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNL 252 Query: 275 PLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLS 334 PLAIII +P+VT Y+L N++YFT ++ ++L S+AVAV FG+ L SWI+P+FV S Sbjct: 253 PLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFS 312 Query: 335 CFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIF 394 G+ NG+ FT+ RL +V REGH+ +LS I + LTP P+++F ++ +Y DI Sbjct: 313 TIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDIN 372 Query: 395 SVINFFSFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVSFWKT 454 S++N+FSF WL L I+G+I +R + ELERPIKV + +PV L +FL+ Sbjct: 373 SLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIISK 432 Query: 455 PV-ECGIGFTIILSGLPVYFFGVWWKNKPKWLLQGIFSTTVLCQKLMQVVPQE 506 P E ILSGL YF V +K W + T+ Q LM+VVP E Sbjct: 433 PTWEYLYCVLFILSGLLFYFLFVHYKF--GWAQKISKPITMHLQMLMEVVPPE 483 >gi|7657591 solute carrier family 7, member 9 [Homo sapiens] Length = 487 Score = 415 bits (1066), Expect = e-116 Identities = 214/473 (45%), Positives = 306/473 (64%), Gaps = 5/473 (1%) Query: 35 SAPAGEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGV 94 S + E + +LQ+ + L++G++IIVGTIIGSGIFV+P VL + G L++WAACGV Sbjct: 15 SIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGV 74 Query: 95 FSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFAT 154 + +GALC+AELGT I+KSGG+Y Y++E YG +PA+L W L++I+P+S I+ L F+ Sbjct: 75 LATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLSFSE 134 Query: 155 YLLKPLFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILL 214 Y+ P + C P+ K +A +L ++ VN SV+ + VQ+ F AAKL+ +A+II+ Sbjct: 135 YVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAIIIIS 194 Query: 215 GFVQIGKGDVSNLDPNFSFEGTKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNL 274 G V + +G+ N D SFEG +L VG I LA Y+GL+AY GWN LN++TEE+ NPYRNL Sbjct: 195 GLVLLAQGNTKNFDN--SFEGAQLSVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNL 252 Query: 275 PLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLS 334 PLAIII +P+VT Y+L N++YFT ++ ++L S+AVAV FG+ L SWI+P+FV S Sbjct: 253 PLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFS 312 Query: 335 CFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIF 394 G+ NG+ FT+ RL +V REGH+ +LS I + LTP P+++F ++ +Y DI Sbjct: 313 TIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDIN 372 Query: 395 SVINFFSFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVSFWKT 454 S++N+FSF WL L I+G+I +R + ELERPIKV + +PV L +FL+ Sbjct: 373 SLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIISK 432 Query: 455 PV-ECGIGFTIILSGLPVYFFGVWWKNKPKWLLQGIFSTTVLCQKLMQVVPQE 506 P E ILSGL YF V +K W + T+ Q LM+VVP E Sbjct: 433 PTWEYLYCVLFILSGLLFYFLFVHYKF--GWAQKISKPITMHLQMLMEVVPPE 483 >gi|33286430 solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 isoform b [Homo sapiens] Length = 332 Score = 322 bits (826), Expect = 4e-88 Identities = 153/294 (52%), Positives = 211/294 (71%), Gaps = 1/294 (0%) Query: 214 LGFVQIGKGDVSNLDPNFSFEG-TKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYR 272 +G VQI KG+ L+P +FE + D+G + LA G FAYGGWN+LN+VTEE+++PY+ Sbjct: 1 MGIVQICKGEYFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYK 60 Query: 273 NLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFVG 332 NLP AI IS+P+VT VYV N+AY T +S +++L+S AVAV FG LGVM+WI+P+ V Sbjct: 61 NLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVA 120 Query: 333 LSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSKD 392 LS FG VNGSLFTSSRLFF G+REGHLPS+L+MIH + TP+P+L+FTC+ TLL + D Sbjct: 121 LSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSD 180 Query: 393 IFSVINFFSFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVSFW 452 ++++IN+ F N+L + + G I LR +KP++ RPIK+NL P+ ++L FL+ S W Sbjct: 181 MYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLW 240 Query: 453 KTPVECGIGFTIILSGLPVYFFGVWWKNKPKWLLQGIFSTTVLCQKLMQVVPQE 506 PV CGIG I+L+G+PVYF GV+W++KPK I T++ QK+ VV E Sbjct: 241 SEPVVCGIGLAIMLTGVPVYFLGVYWQHKPKCFSDFIELLTLVSQKMCVVVYPE 294 >gi|71999149 solute carrier family 7, (cationic amino acid transporter, y+ system) member 13 [Homo sapiens] Length = 470 Score = 222 bits (565), Expect = 7e-58 Identities = 136/449 (30%), Positives = 238/449 (53%), Gaps = 9/449 (2%) Query: 41 GEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLK-EAGSPGLALVVWAACGVFSIVG 99 GE + L+R G + ++ IIG+GIFV+P GVL + G++L VWA C + ++ Sbjct: 4 GEKIQLKRVFGYWWGTSFLLINIIGAGIFVSPKGVLAYSCMNVGVSLCVWAGCAILAMTS 63 Query: 100 ALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIV--ALVFATYLL 157 LC AE+ + SG Y ++ +GS AFL LW L + S + AL+ A Y + Sbjct: 64 TLCSAEISISFPCSGAQYYFLKRYFGSTVAFLNLWTSLFL---GSGVVAGQALLLAEYSI 120 Query: 158 KPLFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFV 217 +P FP+C VP+ K +A + ++ + VK T +Q A + K+ L+ I L G V Sbjct: 121 QPFFPSCSVPKLPKKCLALAMLWIVGILTSRGVKEVTWLQIASSVLKVSILSFISLTGVV 180 Query: 218 QIGKGDVSNLDP-NFSFEGTKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPL 276 + +G N++ +F+ D+ +++ A++ G FAY G + E+ P +P Sbjct: 181 FLIRGKKENVERFQNAFDAELPDISHLIQAIFQGYFAYSGGACFTLIAGELKKPRTTIPK 240 Query: 277 AIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLSCF 336 I +LP+VT+VY+L N++Y T L+ ++LSS+AVA+ + + ++WI+P + S F Sbjct: 241 CIFTALPLVTVVYLLVNISYLTVLTPREILSSDAVAITWADRAFPSLAWIMPFAISTSLF 300 Query: 337 GSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSV 396 ++ S+F SSR ++ S+EG LP + + ++ +P +++ + L + + Sbjct: 301 SNLLISIFKSSRPIYLASQEGQLPLLFNTLNSH-SSPFTAVLLLVTLGSLAIILTSLIDL 359 Query: 397 INFFSFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVSFWKTP- 455 IN+ F L L +IG++ R+++P L P KV L+ P+ I+ + L+ + K+P Sbjct: 360 INYIFFTGSLWSILLMIGILRRRYQEPNLSIPYKVFLSFPLATIVIDVGLVVIPLVKSPN 419 Query: 456 VECGIGFTIILSGLPVYFFGVWWKNKPKW 484 V ++LSGL Y + +K + W Sbjct: 420 VHYVYVLLLVLSGLLFYIPLIHFKIRLAW 448 >gi|114326550 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 [Homo sapiens] Length = 619 Score = 108 bits (271), Expect = 9e-24 Identities = 105/411 (25%), Positives = 179/411 (43%), Gaps = 42/411 (10%) Query: 46 LQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALCYAE 105 L R ++ L+ VA+ VG+ +G+G++V V K+ P + ++ + + S++ LCYAE Sbjct: 28 LARCLSTLDLVALGVGSTLGAGVYVLAGEVAKDKAGPSI-VICFLVAALSSVLAGLCYAE 86 Query: 106 LGTTISKSGGDYAYMLEVYGSLPAFLKLWIELL--------IIRPSSQYIVALVFATYLL 157 G + +SG Y Y G L AF W +L + R S L+ ++ Sbjct: 87 FGARVPRSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNLI-GNHIS 145 Query: 158 KPLFPTCP--VPEEAAK---LVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALII 212 K L + VP A+ A VLLLT + + V F LL L ++ Sbjct: 146 KTLQGSIALHVPHVLAEYPDFFALGLVLLLTGLLALGASESALVTKVFTGVNLLVLGFVM 205 Query: 213 LLGFVQIGKGDVSN------------LDPNFSFEGTKLDVGNIVLALYSGL--------F 252 + GFV KGDV N + N ++ L G V + G+ + Sbjct: 206 ISGFV---KGDVHNWKLTEEDYELAMAELNDTYSLGPLGSGGFVPFGFEGILRGAATCFY 262 Query: 253 AYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVA 312 A+ G++ + EE NP R++P+ I+ISL + L Y + A + Q+ + Sbjct: 263 AFVGFDCIATTGEEAQNPQRSIPMGIVISLSVCFLAYFAVSSALTLMMPYYQLQPESPLP 322 Query: 313 VDFGNYHLGVMSWIIPVFVGLSCFGSVN--GSLFTSSRLFFVGSREGHLPSILSMIHPQL 370 F ++G V VG C S + GS+F R+ + + +G L +L+ IH Sbjct: 323 EAF--LYIGWAPARYVVAVGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFRVLARIHTGT 380 Query: 371 LTPVPSLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRHR 421 TP+ + V + ++ AF + +++ S L +L I ++ LR++ Sbjct: 381 RTPIIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLLAYSLVSICVLILRYQ 431 >gi|114326544 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 [Homo sapiens] Length = 619 Score = 108 bits (271), Expect = 9e-24 Identities = 105/411 (25%), Positives = 179/411 (43%), Gaps = 42/411 (10%) Query: 46 LQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALCYAE 105 L R ++ L+ VA+ VG+ +G+G++V V K+ P + ++ + + S++ LCYAE Sbjct: 28 LARCLSTLDLVALGVGSTLGAGVYVLAGEVAKDKAGPSI-VICFLVAALSSVLAGLCYAE 86 Query: 106 LGTTISKSGGDYAYMLEVYGSLPAFLKLWIELL--------IIRPSSQYIVALVFATYLL 157 G + +SG Y Y G L AF W +L + R S L+ ++ Sbjct: 87 FGARVPRSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNLI-GNHIS 145 Query: 158 KPLFPTCP--VPEEAAK---LVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALII 212 K L + VP A+ A VLLLT + + V F LL L ++ Sbjct: 146 KTLQGSIALHVPHVLAEYPDFFALGLVLLLTGLLALGASESALVTKVFTGVNLLVLGFVM 205 Query: 213 LLGFVQIGKGDVSN------------LDPNFSFEGTKLDVGNIVLALYSGL--------F 252 + GFV KGDV N + N ++ L G V + G+ + Sbjct: 206 ISGFV---KGDVHNWKLTEEDYELAMAELNDTYSLGPLGSGGFVPFGFEGILRGAATCFY 262 Query: 253 AYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVA 312 A+ G++ + EE NP R++P+ I+ISL + L Y + A + Q+ + Sbjct: 263 AFVGFDCIATTGEEAQNPQRSIPMGIVISLSVCFLAYFAVSSALTLMMPYYQLQPESPLP 322 Query: 313 VDFGNYHLGVMSWIIPVFVGLSCFGSVN--GSLFTSSRLFFVGSREGHLPSILSMIHPQL 370 F ++G V VG C S + GS+F R+ + + +G L +L+ IH Sbjct: 323 EAF--LYIGWAPARYVVAVGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFRVLARIHTGT 380 Query: 371 LTPVPSLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRHR 421 TP+ + V + ++ AF + +++ S L +L I ++ LR++ Sbjct: 381 RTPIIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLLAYSLVSICVLILRYQ 431 >gi|110347453 solute carrier family 7 (cationic amino acid transporter, y+ system), member 4 [Homo sapiens] Length = 635 Score = 108 bits (271), Expect = 9e-24 Identities = 98/394 (24%), Positives = 175/394 (44%), Gaps = 25/394 (6%) Query: 45 TLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALCYA 104 +L+R ++ L+ + VG ++GSG++V V KE P + L+ + V S++ ALCYA Sbjct: 32 SLRRCLSTLDLTLLGVGGMVGSGLYVLTGAVAKEVAGPAV-LLSFGVAAVASLLAALCYA 90 Query: 105 ELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELL--------IIRPSSQYIVALVFATYL 156 E G + ++G Y + G L AFL W LL + R S Y+ ++ ++ Sbjct: 91 EFGARVPRTGSAYLFTYVSMGELWAFLIGWNVLLEYIIGGAAVARAWSGYLDSMF--SHS 148 Query: 157 LKPLFPT------CPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALAL 210 ++ T P+ +A +LL +A + ++ + F+A LL + Sbjct: 149 IRNFTETHVGSWQVPLLGHYPDFLAAGIILLASAFVSCGARVSSWLNHTFSAISLLVILF 208 Query: 211 IILLGFVQIGKGDVSNLDPNFSFEGTKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINP 270 I++LGF+ + S + F+ G ++ S +A+ G++ + +EE NP Sbjct: 209 IVILGFILAQPHNWSADEGGFAPFG----FSGVMAGTASCFYAFVGFDVIAASSEEAQNP 264 Query: 271 YRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVF 330 R++PLAI ISL I Y+L + + + A+A F Y G V Sbjct: 265 RRSVPLAIAISLAIAAGAYILVSTVLTLMVPWHSLDPDSALADAF--YQRGYRWAGFIVA 322 Query: 331 VGLSCFGS--VNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYA 388 G C + + LF+ R+ + + +G + + +HP+ PV + ++T A Sbjct: 323 AGSICAMNTVLLSLLFSLPRIVYAMAADGLFFQVFAHVHPRTQVPVAGTLAFGLLTAFLA 382 Query: 389 FSKDIFSVINFFSFFNWLCVALAIIGMIWLRHRK 422 D+ S++ F S L +I LR +K Sbjct: 383 LLLDLESLVQFLSLGTLLAYTFVATSIIVLRFQK 416 >gi|4507047 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 [Homo sapiens] Length = 629 Score = 100 bits (250), Expect = 2e-21 Identities = 105/434 (24%), Positives = 186/434 (42%), Gaps = 47/434 (10%) Query: 24 EKMLAAKSADGSAPAGEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPG 83 ++ML K D S E L R + + VA+ VG+ +G+G++V V +E P Sbjct: 11 QQMLRRKVVDCSR-----EETRLSRCLNTFDLVALGVGSTLGAGVYVLAGAVARENAGPA 65 Query: 84 LALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLW---IELLII 140 + ++ + + S++ LCY E G + K+G Y Y G L AF+ W + +I Sbjct: 66 I-VISFLIAALASVLAGLCYGEFGARVPKTGSAYLYSYVTVGELWAFITGWNLILSYIIG 124 Query: 141 RPSSQYIVALVFATYLLKPL------FPTCPVP---EEAAKLVACLCVLLLTAVNCYSVK 191 S + F + +P+ T P E + A + +L+LT + VK Sbjct: 125 TSSVARAWSATFDELIGRPIGEFSRTHMTLNAPGVLAENPDIFAVIIILILTGLLTLGVK 184 Query: 192 AATRVQDAFAAAKLLALALIILLGFVQIGKGDVSN--------------LDPNFSFEGTK 237 + V F +L L I++ GFV KG V N L N + K Sbjct: 185 ESAMVNKIFTCINVLVLGFIMVSGFV---KGSVKNWQLTEEDFGNTSGRLCLNNDTKEGK 241 Query: 238 LDVGNIVLALYSGL--------FAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVY 289 VG + +SG+ +A+ G++ + EE+ NP + +P+ I+ SL I + Y Sbjct: 242 PGVGGFMPFGFSGVLSGAATCFYAFVGFDCIATTGEEVKNPQKAIPVGIVASLLICFIAY 301 Query: 290 VLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLSC--FGSVNGSLFTSS 347 + A T + L + + D H+G V VG C S+ GS+F Sbjct: 302 FGVSAA-LTLMMPYFCLDNNSPLPD-AFKHVGWEGAKYAVAVGSLCALSASLLGSMFPMP 359 Query: 348 RLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFFSFFNWLC 407 R+ + + +G L L+ ++ + TP+ + + + + + AF D+ +++ S L Sbjct: 360 RVIYAMAEDGLLFKFLANVNDRTKTPIIATLASGAVAAVMAFLFDLKDLVDLMSIGTLLA 419 Query: 408 VALAIIGMIWLRHR 421 +L ++ LR++ Sbjct: 420 YSLVAACVLVLRYQ 433 >gi|134304858 solute carrier family 7, member 2 isoform 2 [Homo sapiens] Length = 658 Score = 98.2 bits (243), Expect = 2e-20 Identities = 92/414 (22%), Positives = 178/414 (42%), Gaps = 38/414 (9%) Query: 42 EGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGAL 101 E L R ++ ++ +A+ VG+ +G+G++V V K P + +V + + S++ L Sbjct: 26 EDTKLCRCLSTMDLIALGVGSTLGAGVYVLAGEVAKADSGPSI-VVSFLIAALASVMAGL 84 Query: 102 CYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELL--IIRPSS---------QYIVAL 150 CYAE G + K+G Y Y G L AF+ W +L +I SS +++ Sbjct: 85 CYAEFGARVPKTGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDELLSK 144 Query: 151 VFATYLLKPLFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALAL 210 +L E A +LLL + + VK + V F A +L L Sbjct: 145 QIGQFLRTYFRMNYTGLAEYPDFFAVCLILLLAGLLSFGVKESAWVNKVFTAVNILVLLF 204 Query: 211 IILLGFVQIGKGDVSNLDPNFSF--------------EGTKL-DVGNIVLALYSG----- 250 +++ GFV KG+V+N + F GT + G + ++G Sbjct: 205 VMVAGFV---KGNVANWKISEEFLKNISASAREPPSENGTSIYGAGGFMPYGFTGTLAGA 261 Query: 251 ---LFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLS 307 +A+ G++ + EE+ NP + +P+ I+ SL + + Y + A + + Sbjct: 262 ATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYLLDE 321 Query: 308 SEAVAVDFGNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIH 367 + V F G +++ + S+ GS+F R+ + + +G L L+ I+ Sbjct: 322 KSPLPVAFEYVGWGPAKYVVAAGSLCALSTSLLGSIFPMPRVIYAMAEDGLLFKCLAQIN 381 Query: 368 PQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRHR 421 + TP+ + + + + L AF D+ ++++ S + +L ++ LR++ Sbjct: 382 SKTKTPIIATLSSGAVAALMAFLFDLKALVDMMSIGTLMAYSLVAACVLILRYQ 435 >gi|109948288 solute carrier family 7, member 2 isoform 1 [Homo sapiens] Length = 697 Score = 96.7 bits (239), Expect = 5e-20 Identities = 94/414 (22%), Positives = 179/414 (43%), Gaps = 39/414 (9%) Query: 42 EGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGAL 101 E L R ++ ++ +A+ VG+ +G+G++V V K P + +V + + S++ L Sbjct: 66 EDTKLCRCLSTMDLIALGVGSTLGAGVYVLAGEVAKADSGPSI-VVSFLIAALASVMAGL 124 Query: 102 CYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELL--IIRPSS---------QYIVAL 150 CYAE G + K+G Y Y G L AF+ W +L +I SS +++ Sbjct: 125 CYAEFGARVPKTGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDELLSK 184 Query: 151 VFATYLLKPLFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALAL 210 +L E A +LLL + + VK + V F A +L L Sbjct: 185 QIGQFLRTYFRMNYTGLAEYPDFFAVCLILLLAGLLSFGVKESAWVNKVFTAVNILVLLF 244 Query: 211 IILLGFVQIGKGDVSNLDPNFSF--------------EGTKL-DVGNIVLALYSG----- 250 +++ GFV KG+V+N + F GT + G + ++G Sbjct: 245 VMVAGFV---KGNVANWKISEEFLKNISASAREPPSENGTSIYGAGGFMPYGFTGTLAGA 301 Query: 251 ---LFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLS 307 +A+ G++ + EE+ NP + +P+ I+ SL + + Y + A + + Sbjct: 302 ATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYLLDE 361 Query: 308 SEAVAVDFGNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIH 367 + V F G +++ + S+ GS+F R+ F +R+G L L+ + Sbjct: 362 KSPLPVAFEYVGWGPAKYVVAAGSLCALSTSLLGSMFPLPRILFAMARDGLLFRFLARVS 421 Query: 368 PQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRHR 421 + +PV + + V++ L AF D+ ++++ S + +L ++ LR++ Sbjct: 422 KR-QSPVAATLTAGVISALMAFLFDLKALVDMMSIGTLMAYSLVAACVLILRYQ 474 >gi|181337167 solute carrier family 7 (cationic amino acid transporter, y+ system), member 14 [Homo sapiens] Length = 771 Score = 85.9 bits (211), Expect = 8e-17 Identities = 95/407 (23%), Positives = 164/407 (40%), Gaps = 48/407 (11%) Query: 43 GVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALC 102 G L + +T ++ +++ VG+ +G+G++V V KE PG+ +V + V SI+ +C Sbjct: 46 GTKLAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAGPGV-IVSFIIAAVASILSGVC 104 Query: 103 YAELGTTISK-SGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPLF 161 YAE G + K +G Y Y G AF W +L +Y++ L +F Sbjct: 105 YAEFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLIL------EYLIGTAAGASALSSMF 158 Query: 162 PTC--------------------PVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFA 201 + E L+A L +++T + VK + + Sbjct: 159 DSLANHTISRWMADSVGTLNGLGKGEESYPDLLALLIAVIVTIIVALGVKNSIGFNNVLN 218 Query: 202 AAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDVG--NIVLALYSGLFAYGGWNY 259 L I++ G I + + EG L G ++ + +A+ G++ Sbjct: 219 VLNLAVWVFIMIAGLFFI--------NGKYWAEGQFLPHGWSGVLQGAATCFYAFIGFDI 270 Query: 260 LNFVTEEMINPYRNLPLAIIISLPIVTLVYV-----LTNLAYFTTLSTEQMLSSEAVAVD 314 + EE NP ++P AI SL I YV LT + + T+ TE L VA Sbjct: 271 IATTGEEAKNPNTSIPYAITASLVICLTAYVSVSVILTLMVPYYTIDTESPLMEMFVAHG 330 Query: 315 FGNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPV 374 F + I GL+ S+ GSLF R+ + + +G L L+ + TPV Sbjct: 331 F---YAAKFVVAIGSVAGLTV--SLLGSLFPMPRVIYAMAGDGLLFRFLAHVSSYTETPV 385 Query: 375 PSLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRHR 421 + + + + L A + +I S L L + ++ LR++ Sbjct: 386 VACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQ 432 >gi|4506975 solute carrier family 12 (sodium/potassium/chloride transporters), member 2 [Homo sapiens] Length = 1212 Score = 33.5 bits (75), Expect = 0.47 Identities = 50/244 (20%), Positives = 95/244 (38%), Gaps = 24/244 (9%) Query: 63 IIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYMLE 122 I G +F+ + ++ +AG LV+ A V +I G A + GG Y + Sbjct: 299 IWGVMLFIRLSWIVGQAGIGLSVLVIMMATVVTTITGLSTSAIATNGFVRGGGAYYLISR 358 Query: 123 VYGSLPAF---LKLWIELLIIRPSSQYIVALVFATYLLKPLFPTCPVPE-EAAKLVACLC 178 G P F + L + Y+V L + E +++ + Sbjct: 359 SLG--PEFGGAIGLIFAFANAVAVAMYVVGFAETVVELLKEHSILMIDEINDIRIIGAIT 416 Query: 179 VLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIG----------KGDV--SN 226 V++L ++ ++ + Q LLA+ ++ F+ + K ++ N Sbjct: 417 VVILLGISVAGMEWEAKAQIVLLVILLLAIGDFVIGTFIPLESKKPKGFFGYKSEIFNEN 476 Query: 227 LDPNFSFEGTKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVT 286 P+F E T V I +G+ A G N ++ ++ +P +P ++++ I T Sbjct: 477 FGPDFREEETFFSVFAIFFPAATGILA--GAN----ISGDLADPQSAIPKGTLLAILITT 530 Query: 287 LVYV 290 LVYV Sbjct: 531 LVYV 534 >gi|41406091 non-imprinted in Prader-Willi/Angelman syndrome 1 isoform 1 [Homo sapiens] Length = 329 Score = 33.1 bits (74), Expect = 0.61 Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 2/76 (2%) Query: 28 AAKSADGSAPAGEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVL--KEAGSPGLA 85 AA +A +A AGEG ++L GVA++ + GS + G++ K G+ L Sbjct: 6 AAAAAAAAAAAGEGARSPSPAAVSLGLGVAVVSSLVNGSTFVLQKKGIVRAKRRGTSYLT 65 Query: 86 LVVWAACGVFSIVGAL 101 +VW A + VG + Sbjct: 66 DIVWWAGTIAMAVGQI 81 >gi|40354216 sine oculis homeobox homolog 5 [Homo sapiens] Length = 739 Score = 33.1 bits (74), Expect = 0.61 Identities = 17/40 (42%), Positives = 24/40 (60%) Query: 4 AGPKRRALAAPAAEEKEEAREKMLAAKSADGSAPAGEGEG 43 AG + A AA EE+EEAR+ + ++A+G A A G G Sbjct: 14 AGGEAVAAAAATEEEEEEARQLLQTLQAAEGEAAAAAGAG 53 >gi|110224458 solute carrier family 12, member 6 isoform e [Homo sapiens] Length = 1135 Score = 32.7 bits (73), Expect = 0.80 Identities = 41/191 (21%), Positives = 79/191 (41%), Gaps = 14/191 (7%) Query: 272 RNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFV 331 +++P+ I+++ + VY L+N+ F +L + GN +G +SW P + Sbjct: 499 KSIPIGTILAILTTSFVY-LSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVI 557 Query: 332 GLSCFGSVNG----SLFTSSRLFFVGSREGHLPSILSMIHPQLL-TPVPSLVFTCVMTLL 386 + F S G SL + RL +++ +P + H + P +L+ T + L Sbjct: 558 VIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAEL 617 Query: 387 YAFSKDIFSVINFFSFFNWLC-----VALAIIGMIWLRHRKPELERPIKVNLALPVFFIL 441 + V S F +C +A A+ ++ + +P + AL + Sbjct: 618 GILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFR---YYHWALSFMGMS 674 Query: 442 ACLFLIAVSFW 452 CL L+ +S W Sbjct: 675 ICLALMFISSW 685 >gi|110224456 solute carrier family 12, member 6 isoform d [Homo sapiens] Length = 1141 Score = 32.7 bits (73), Expect = 0.80 Identities = 41/191 (21%), Positives = 79/191 (41%), Gaps = 14/191 (7%) Query: 272 RNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFV 331 +++P+ I+++ + VY L+N+ F +L + GN +G +SW P + Sbjct: 505 KSIPIGTILAILTTSFVY-LSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVI 563 Query: 332 GLSCFGSVNG----SLFTSSRLFFVGSREGHLPSILSMIHPQLL-TPVPSLVFTCVMTLL 386 + F S G SL + RL +++ +P + H + P +L+ T + L Sbjct: 564 VIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAEL 623 Query: 387 YAFSKDIFSVINFFSFFNWLC-----VALAIIGMIWLRHRKPELERPIKVNLALPVFFIL 441 + V S F +C +A A+ ++ + +P + AL + Sbjct: 624 GILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFR---YYHWALSFMGMS 680 Query: 442 ACLFLIAVSFW 452 CL L+ +S W Sbjct: 681 ICLALMFISSW 691 >gi|110224454 solute carrier family 12, member 6 isoform c [Homo sapiens] Length = 1091 Score = 32.7 bits (73), Expect = 0.80 Identities = 41/191 (21%), Positives = 79/191 (41%), Gaps = 14/191 (7%) Query: 272 RNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFV 331 +++P+ I+++ + VY L+N+ F +L + GN +G +SW P + Sbjct: 455 KSIPIGTILAILTTSFVY-LSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVI 513 Query: 332 GLSCFGSVNG----SLFTSSRLFFVGSREGHLPSILSMIHPQLL-TPVPSLVFTCVMTLL 386 + F S G SL + RL +++ +P + H + P +L+ T + L Sbjct: 514 VIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAEL 573 Query: 387 YAFSKDIFSVINFFSFFNWLC-----VALAIIGMIWLRHRKPELERPIKVNLALPVFFIL 441 + V S F +C +A A+ ++ + +P + AL + Sbjct: 574 GILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFR---YYHWALSFMGMS 630 Query: 442 ACLFLIAVSFW 452 CL L+ +S W Sbjct: 631 ICLALMFISSW 641 >gi|110224452 solute carrier family 12, member 6 isoform c [Homo sapiens] Length = 1091 Score = 32.7 bits (73), Expect = 0.80 Identities = 41/191 (21%), Positives = 79/191 (41%), Gaps = 14/191 (7%) Query: 272 RNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFV 331 +++P+ I+++ + VY L+N+ F +L + GN +G +SW P + Sbjct: 455 KSIPIGTILAILTTSFVY-LSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVI 513 Query: 332 GLSCFGSVNG----SLFTSSRLFFVGSREGHLPSILSMIHPQLL-TPVPSLVFTCVMTLL 386 + F S G SL + RL +++ +P + H + P +L+ T + L Sbjct: 514 VIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAEL 573 Query: 387 YAFSKDIFSVINFFSFFNWLC-----VALAIIGMIWLRHRKPELERPIKVNLALPVFFIL 441 + V S F +C +A A+ ++ + +P + AL + Sbjct: 574 GILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFR---YYHWALSFMGMS 630 Query: 442 ACLFLIAVSFW 452 CL L+ +S W Sbjct: 631 ICLALMFISSW 641 >gi|4826780 solute carrier family 12, member 6 isoform b [Homo sapiens] Length = 1099 Score = 32.7 bits (73), Expect = 0.80 Identities = 41/191 (21%), Positives = 79/191 (41%), Gaps = 14/191 (7%) Query: 272 RNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFV 331 +++P+ I+++ + VY L+N+ F +L + GN +G +SW P + Sbjct: 463 KSIPIGTILAILTTSFVY-LSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVI 521 Query: 332 GLSCFGSVNG----SLFTSSRLFFVGSREGHLPSILSMIHPQLL-TPVPSLVFTCVMTLL 386 + F S G SL + RL +++ +P + H + P +L+ T + L Sbjct: 522 VIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAEL 581 Query: 387 YAFSKDIFSVINFFSFFNWLC-----VALAIIGMIWLRHRKPELERPIKVNLALPVFFIL 441 + V S F +C +A A+ ++ + +P + AL + Sbjct: 582 GILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFR---YYHWALSFMGMS 638 Query: 442 ACLFLIAVSFW 452 CL L+ +S W Sbjct: 639 ICLALMFISSW 649 >gi|110224449 solute carrier family 12, member 6 isoform a [Homo sapiens] Length = 1150 Score = 32.7 bits (73), Expect = 0.80 Identities = 41/191 (21%), Positives = 79/191 (41%), Gaps = 14/191 (7%) Query: 272 RNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFV 331 +++P+ I+++ + VY L+N+ F +L + GN +G +SW P + Sbjct: 514 KSIPIGTILAILTTSFVY-LSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVI 572 Query: 332 GLSCFGSVNG----SLFTSSRLFFVGSREGHLPSILSMIHPQLL-TPVPSLVFTCVMTLL 386 + F S G SL + RL +++ +P + H + P +L+ T + L Sbjct: 573 VIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAEL 632 Query: 387 YAFSKDIFSVINFFSFFNWLC-----VALAIIGMIWLRHRKPELERPIKVNLALPVFFIL 441 + V S F +C +A A+ ++ + +P + AL + Sbjct: 633 GILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFR---YYHWALSFMGMS 689 Query: 442 ACLFLIAVSFW 452 CL L+ +S W Sbjct: 690 ICLALMFISSW 700 >gi|16418463 MAS1 oncogene-like [Homo sapiens] Length = 378 Score = 32.0 bits (71), Expect = 1.4 Identities = 36/148 (24%), Positives = 65/148 (43%), Gaps = 18/148 (12%) Query: 335 CFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLL-----YAF 389 C +NG++F L G+ ++ IL ++ ++ S V +TLL F Sbjct: 88 CGVLLNGTVFW---LLCCGATNPYMVYILHLVAADVIYLCCSAVGFLQVTLLTYHGVVFF 144 Query: 390 SKDIFSVINFFSFFNWLCVALAI--------IGMIWLRHRKPELERPIKVNLALPVFFIL 441 D ++++ FSF LC+ +AI + IW R +P+ + L + F + Sbjct: 145 IPDFLAILSPFSFEVCLCLLVAISTERCVCVLFPIWYRCHRPKYTSNVVCTLIWGLPFCI 204 Query: 442 ACLFLIAVSFWKTPVECGIGFTIILSGL 469 + + +++WK C I + LSGL Sbjct: 205 NIVKSLFLTYWKHVKACVI--FLKLSGL 230 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.326 0.141 0.435 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 18,564,508 Number of Sequences: 37866 Number of extensions: 814899 Number of successful extensions: 2999 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 22 Number of HSP's successfully gapped in prelim test: 20 Number of HSP's that attempted gapping in prelim test: 2899 Number of HSP's gapped (non-prelim): 59 length of query: 507 length of database: 18,247,518 effective HSP length: 107 effective length of query: 400 effective length of database: 14,195,856 effective search space: 5678342400 effective search space used: 5678342400 T: 11 A: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.