Search of human proteins with 71043498

Search of human proteins with 71043498

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|71043498 alkaline ceramidase 2 [Homo sapiens]
         (275 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|71043498 alkaline ceramidase 2 [Homo sapiens]                      583   e-167
gi|19424128 alkaline ceramidase 1 [Homo sapiens]                      211   7e-55
gi|170932467 phytoceramidase, alkaline [Homo sapiens]                  76   3e-14
gi|5453796 neuropeptide Y receptor Y5 [Homo sapiens]                   30   2.3  
gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]    30   3.0  
gi|21361300 lens intrinsic membrane protein 2, 19kDa isoform 1 [...    29   3.9  
gi|169209545 PREDICTED: hypothetical protein [Homo sapiens]            29   3.9  
gi|169210556 PREDICTED: hypothetical protein [Homo sapiens]            29   3.9  
gi|169210041 PREDICTED: hypothetical protein [Homo sapiens]            29   3.9  
gi|239916002 lens intrinsic membrane protein 2, 19kDa isoform 2 ...    29   5.1  
gi|239046738 Nedd4 family interacting protein 2 isoform 1 [Homo ...    28   6.7  

>gi|71043498 alkaline ceramidase 2 [Homo sapiens]
          Length = 275

 Score =  583 bits (1502), Expect = e-167
 Identities = 275/275 (100%), Positives = 275/275 (100%)

Query: 1   MGAPHWWDQLQAGSSEVDWCEDNYTIVPAIAEFYNTISNVLFFILPPICMCLFRQYATCF 60
           MGAPHWWDQLQAGSSEVDWCEDNYTIVPAIAEFYNTISNVLFFILPPICMCLFRQYATCF
Sbjct: 1   MGAPHWWDQLQAGSSEVDWCEDNYTIVPAIAEFYNTISNVLFFILPPICMCLFRQYATCF 60

Query: 61  NSGIYLIWTLLVVVGIGSVYFHATLSFLGQMLDELAVLWVLMCALAMWFPRRYLPKIFRN 120
           NSGIYLIWTLLVVVGIGSVYFHATLSFLGQMLDELAVLWVLMCALAMWFPRRYLPKIFRN
Sbjct: 61  NSGIYLIWTLLVVVGIGSVYFHATLSFLGQMLDELAVLWVLMCALAMWFPRRYLPKIFRN 120

Query: 121 DRGRFKVVVSVLSAVTTCLAFVKPAINNISLMTLGVPCTALLIAELKRCDNMRVFKLGLF 180
           DRGRFKVVVSVLSAVTTCLAFVKPAINNISLMTLGVPCTALLIAELKRCDNMRVFKLGLF
Sbjct: 121 DRGRFKVVVSVLSAVTTCLAFVKPAINNISLMTLGVPCTALLIAELKRCDNMRVFKLGLF 180

Query: 181 SGLWWTLALFCWISDRAFCELLSSFNFPYLHCMWHILICLAAYLGCVCFAYFDAASEIPE 240
           SGLWWTLALFCWISDRAFCELLSSFNFPYLHCMWHILICLAAYLGCVCFAYFDAASEIPE
Sbjct: 181 SGLWWTLALFCWISDRAFCELLSSFNFPYLHCMWHILICLAAYLGCVCFAYFDAASEIPE 240

Query: 241 QGPVIKFWPNEKWAFIGVPYVSLLCANKKSSVKIT 275
           QGPVIKFWPNEKWAFIGVPYVSLLCANKKSSVKIT
Sbjct: 241 QGPVIKFWPNEKWAFIGVPYVSLLCANKKSSVKIT 275


>gi|19424128 alkaline ceramidase 1 [Homo sapiens]
          Length = 264

 Score =  211 bits (536), Expect = 7e-55
 Identities = 98/250 (39%), Positives = 150/250 (60%), Gaps = 1/250 (0%)

Query: 14  SSEVDWCEDNYTIVPAIAEFYNTISNVLFFILPPICMCLFRQYATCFNSGIYLIWTLLVV 73
           SSEVDWCE N+     +AEFYNT SN+ FFI  P+ M L   YA   +  IY++W L ++
Sbjct: 9   SSEVDWCESNFQYSELVAEFYNTFSNIPFFIFGPLMMLLMHPYAQKRSRYIYVVWVLFMI 68

Query: 74  VGIGSVYFHATLSFLGQMLDELAVLWVLMCALAMWFPRRYLPKIFRNDRGRFKVVVSVLS 133
           +G+ S+YFH TLSFLGQ+LDE+A+LW+L    ++W PR Y P     +R +F  +V + +
Sbjct: 69  IGLFSMYFHMTLSFLGQLLDEIAILWLLGSGYSIWMPRCYFPSFLGGNRSQFIRLVFITT 128

Query: 134 AVTTCLAFVKPAINNISLMTLGVPCTALLIAELKRCDNMRVFKLGLFSGLWWTLALFCWI 193
            V+T L+F++P +N  +L ++ +    ++  E ++  N  +  L   S + W +AL  WI
Sbjct: 129 VVSTLLSFLRPTVNAYALNSIALHILYIVCQEYRKTSNKELRHLIEVSVVLWAVALTSWI 188

Query: 194 SDRAFCELLSSFNFPYLHCMWHILICLAAYLGCVCFAYFDAASEIPEQGPVIKFWPNEKW 253
           SDR  C      +F YLH +WH+LI +    G V  A  DA  E+P +   +++WP + W
Sbjct: 189 SDRLLCSFWQRIHFFYLHSIWHVLISITFPYGMVTMALVDANYEMPGETLKVRYWPRDSW 248

Query: 254 AFIGVPYVSL 263
             +G+PYV +
Sbjct: 249 P-VGLPYVEI 257


>gi|170932467 phytoceramidase, alkaline [Homo sapiens]
          Length = 267

 Score = 76.3 bits (186), Expect = 3e-14
 Identities = 64/224 (28%), Positives = 96/224 (42%), Gaps = 21/224 (9%)

Query: 14  SSEVDWCEDNYTIVPAIAEFYNTISNVLFFILPPICMCLFRQYATCFNSGIYLIWTLLVV 73
           +S +DWCE+NY++   IAEF+NT+SN L  I+PP+   + +             +  L V
Sbjct: 15  TSTLDWCEENYSVTWYIAEFWNTVSN-LIMIIPPMFGAV-QSVRDGLEKRYIASYLALTV 72

Query: 74  VGIGSVYFHATLSFLGQMLDELAVLWVLMCALAMWFPRRYLPKIFRNDRGRFKVVVSVLS 133
           VG+GS  FH TL +  Q+LDEL +++   C         +  K   N    F +V+  L 
Sbjct: 73  VGMGSWCFHMTLKYEMQLLDELPMIY-SCCIFVYCMFECFKIKNSVNYHLLFTLVLFSLI 131

Query: 134 AVTTCLAFVKPAINNIS----LMTLGVPCTALLIAELKRCDNMRVFKLGLFSGLWWTLAL 189
             T  L   +P  + +     + TL +    ++         +    LG+F      L  
Sbjct: 132 VTTVYLKVKEPIFHQVMYGMLVFTLVLRSIYIVTWVYPWLRGLGYTSLGIF-----LLGF 186

Query: 190 FCWISDRAFCELLSSFN---------FPYLHCMWHILICLAAYL 224
             W  D  FCE L +F              H  WHIL  L +YL
Sbjct: 187 LFWNIDNIFCESLRNFRKKVPPIIGITTQFHAWWHILTGLGSYL 230


>gi|5453796 neuropeptide Y receptor Y5 [Homo sapiens]
          Length = 445

 Score = 30.0 bits (66), Expect = 2.3
 Identities = 31/123 (25%), Positives = 57/123 (46%), Gaps = 4/123 (3%)

Query: 112 RYLPKIFRNDRGRFKVVVSVLSAVTTCLAFVKPAINNISLMTLGVPCTALLIAELKRCDN 171
           R LP+ F + R +       +  V TC   +KP  N+  +  L V  +   I +  R   
Sbjct: 310 RILPENFGSVRSQLSSSSKFIPGVPTCFE-IKPEENS-DVHELRVKRSVTRIKKRSRSVF 367

Query: 172 MRVFKLGL-FSGLWWTLALFCWISDRAFCELLSSFNFPYLHCMWHILICLAAYLGCVCFA 230
            R+  L L F+  W  L LF  ++D     L+S+ +F  ++C+ H+L  ++  L  + + 
Sbjct: 368 YRLTILILVFAVSWMPLHLFHVVTDFND-NLISNRHFKLVYCICHLLGMMSCCLNPILYG 426

Query: 231 YFD 233
           + +
Sbjct: 427 FLN 429


>gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]
          Length = 1039

 Score = 29.6 bits (65), Expect = 3.0
 Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 17/82 (20%)

Query: 177 LGLFSGLWWTLALFCWIS--DRAFCELLSSFNFPYLHCMWHILICLAAYLGCVCFAYFDA 234
           +G FS L W  A  CWI+   +   +  +S N  YL C+  +++ L        FAY+  
Sbjct: 112 VGGFSILLWVGAFLCWIAYGIQYSSDKSASLNNVYLGCVLGLVVILTG-----IFAYYQE 166

Query: 235 ASE----------IPEQGPVIK 246
           A            IP+Q  VI+
Sbjct: 167 AKSTNIMSSFNKMIPQQALVIR 188


>gi|21361300 lens intrinsic membrane protein 2, 19kDa isoform 1
           [Homo sapiens]
          Length = 215

 Score = 29.3 bits (64), Expect = 3.9
 Identities = 21/88 (23%), Positives = 39/88 (44%), Gaps = 5/88 (5%)

Query: 13  GSSEVDWCEDN-YTIVPAIAEFYNTISNVLFFILPPICMCLFRQYATCFNSGIYLIWTLL 71
           G+++  W     + I+ A+      I  ++ F   P     F + +  F++GI    + L
Sbjct: 97  GATQAYWNATRAFMILSALCAISGIIMGIMAFAHQPT----FSRISRPFSAGIMFFSSTL 152

Query: 72  VVVGIGSVYFHATLSFLGQMLDELAVLW 99
            VV   ++Y   T+SFLG+   +    W
Sbjct: 153 FVVLALAIYTGVTVSFLGRRFGDWRFSW 180


>gi|169209545 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 237

 Score = 29.3 bits (64), Expect = 3.9
 Identities = 9/19 (47%), Positives = 12/19 (63%)

Query: 210 LHCMWHILICLAAYLGCVC 228
           L   WH+L C+A  +GC C
Sbjct: 179 LRISWHLLACVATQVGCAC 197


>gi|169210556 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 237

 Score = 29.3 bits (64), Expect = 3.9
 Identities = 9/19 (47%), Positives = 12/19 (63%)

Query: 210 LHCMWHILICLAAYLGCVC 228
           L   WH+L C+A  +GC C
Sbjct: 179 LRISWHLLACVATQVGCAC 197


>gi|169210041 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 237

 Score = 29.3 bits (64), Expect = 3.9
 Identities = 9/19 (47%), Positives = 12/19 (63%)

Query: 210 LHCMWHILICLAAYLGCVC 228
           L   WH+L C+A  +GC C
Sbjct: 179 LRISWHLLACVATQVGCAC 197


>gi|239916002 lens intrinsic membrane protein 2, 19kDa isoform 2
           [Homo sapiens]
          Length = 173

 Score = 28.9 bits (63), Expect = 5.1
 Identities = 19/76 (25%), Positives = 34/76 (44%), Gaps = 4/76 (5%)

Query: 24  YTIVPAIAEFYNTISNVLFFILPPICMCLFRQYATCFNSGIYLIWTLLVVVGIGSVYFHA 83
           + I+ A+      I  ++ F   P     F + +  F++GI    + L VV   ++Y   
Sbjct: 67  FMILSALCAISGIIMGIMAFAHQPT----FSRISRPFSAGIMFFSSTLFVVLALAIYTGV 122

Query: 84  TLSFLGQMLDELAVLW 99
           T+SFLG+   +    W
Sbjct: 123 TVSFLGRRFGDWRFSW 138


>gi|239046738 Nedd4 family interacting protein 2 isoform 1 [Homo
           sapiens]
          Length = 336

 Score = 28.5 bits (62), Expect = 6.7
 Identities = 16/66 (24%), Positives = 33/66 (50%), Gaps = 1/66 (1%)

Query: 23  NYTIVPAIAEFYNTISNVLFFILPPICMCLFRQYATCFNSGIYLIWTLLVVVGIGSVYFH 82
           ++ I   IA  Y  I      ++  I +  F  Y T + +G Y +W + +V+G+  ++F 
Sbjct: 251 SFCITNTIAGRYGAICGFGLSLIKWILIVRFSDYFTGYFNGQYWLWWIFLVLGL-LLFFR 309

Query: 83  ATLSFL 88
             +++L
Sbjct: 310 GFVNYL 315


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.332    0.142    0.499 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,957,043
Number of Sequences: 37866
Number of extensions: 399507
Number of successful extensions: 961
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 952
Number of HSP's gapped (non-prelim): 12
length of query: 275
length of database: 18,247,518
effective HSP length: 101
effective length of query: 174
effective length of database: 14,423,052
effective search space: 2509611048
effective search space used: 2509611048
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.