Search of human proteins with 70995422

Search of human proteins with 70995422

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|70995422 NAD(P)H menadione oxidoreductase 1,
dioxin-inducible isoform c [Homo sapiens]
         (236 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|70995422 NAD(P)H menadione oxidoreductase 1, dioxin-inducible...   474   e-134
gi|4505415 NAD(P)H menadione oxidoreductase 1, dioxin-inducible ...   456   e-128
gi|70995396 NAD(P)H menadione oxidoreductase 1, dioxin-inducible...   395   e-110
gi|156564357 NAD(P)H dehydrogenase, quinone 2 [Homo sapiens]          158   3e-39
gi|116256363 transmembrane protease, serine 13 [Homo sapiens]          30   1.4  
gi|74048554 cancer susceptibility candidate 5 isoform 2 [Homo sa...    29   3.1  
gi|74048514 cancer susceptibility candidate 5 isoform 1 [Homo sa...    29   3.1  
gi|62821787 COBL-like 1 [Homo sapiens]                                 29   4.0  
gi|4557303 aldehyde dehydrogenase 3A2 isoform 2 [Homo sapiens]         28   5.3  
gi|73466520 aldehyde dehydrogenase 3A2 isoform 1 [Homo sapiens]        28   5.3  
gi|4504327 mitochondrial trifunctional protein, beta subunit pre...    28   6.9  
gi|170932492 transmembrane protease, serine 5 [Homo sapiens]           28   6.9  
gi|39725717 coiled-coil domain containing 141 [Homo sapiens]           28   6.9  
gi|153792074 proline rich 12 [Homo sapiens]                            28   9.0  

>gi|70995422 NAD(P)H menadione oxidoreductase 1, dioxin-inducible
           isoform c [Homo sapiens]
          Length = 236

 Score =  474 bits (1221), Expect = e-134
 Identities = 236/236 (100%), Positives = 236/236 (100%)

Query: 1   MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL 60
           MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL
Sbjct: 1   MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL 60

Query: 61  KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQSKKAVLSITTGGSGSMYSL 120
           KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQSKKAVLSITTGGSGSMYSL
Sbjct: 61  KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQSKKAVLSITTGGSGSMYSL 120

Query: 121 QGIHGDMNVILWPIQSGILHFCGFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDE 180
           QGIHGDMNVILWPIQSGILHFCGFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDE
Sbjct: 121 QGIHGDMNVILWPIQSGILHFCGFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDE 180

Query: 181 TPLYFAPSSLFDLNFQAGFLMKKEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK 236
           TPLYFAPSSLFDLNFQAGFLMKKEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK
Sbjct: 181 TPLYFAPSSLFDLNFQAGFLMKKEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK 236


>gi|4505415 NAD(P)H menadione oxidoreductase 1, dioxin-inducible
           isoform a [Homo sapiens]
          Length = 274

 Score =  456 bits (1172), Expect = e-128
 Identities = 236/274 (86%), Positives = 236/274 (86%), Gaps = 38/274 (13%)

Query: 1   MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL 60
           MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL
Sbjct: 1   MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL 60

Query: 61  KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQ------------------- 101
           KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQ                   
Sbjct: 61  KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV 120

Query: 102 -------------------SKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFC 142
                              SKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFC
Sbjct: 121 FIGEFAYTYAAMYDKGPFRSKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFC 180

Query: 143 GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK 202
           GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK
Sbjct: 181 GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK 240

Query: 203 KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK 236
           KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK
Sbjct: 241 KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK 274


>gi|70995396 NAD(P)H menadione oxidoreductase 1, dioxin-inducible
           isoform b [Homo sapiens]
          Length = 240

 Score =  395 bits (1016), Expect = e-110
 Identities = 208/247 (84%), Positives = 212/247 (85%), Gaps = 18/247 (7%)

Query: 1   MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL 60
           MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL
Sbjct: 1   MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL 60

Query: 61  KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQ------SKKAVLS-----I 109
           KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQ         A+L      +
Sbjct: 61  KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV 120

Query: 110 TTGGSGSMYSLQGIHGDMNVILWPIQSGILHFCGFQVLEPQLTYSIGHTPADARIQILEG 169
             G     Y+     G       P +SGILHFCGFQVLEPQLTYSIGHTPADARIQILEG
Sbjct: 121 FIGEFAYTYAAMYDKG-------PFRSGILHFCGFQVLEPQLTYSIGHTPADARIQILEG 173

Query: 170 WKKRLENIWDETPLYFAPSSLFDLNFQAGFLMKKEVQDEEKNKKFGLSVGHHLGKSIPTD 229
           WKKRLENIWDETPLYFAPSSLFDLNFQAGFLMKKEVQDEEKNKKFGLSVGHHLGKSIPTD
Sbjct: 174 WKKRLENIWDETPLYFAPSSLFDLNFQAGFLMKKEVQDEEKNKKFGLSVGHHLGKSIPTD 233

Query: 230 NQIKARK 236
           NQIKARK
Sbjct: 234 NQIKARK 240


>gi|156564357 NAD(P)H dehydrogenase, quinone 2 [Homo sapiens]
          Length = 231

 Score =  158 bits (400), Expect = 3e-39
 Identities = 87/221 (39%), Positives = 117/221 (52%), Gaps = 38/221 (17%)

Query: 1   MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL 60
           M G++ LIV AH E  SFN ++K  A   L ++G  V  SDLYAMN  P  + KDITG L
Sbjct: 1   MAGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNLEPRATDKDITGTL 60

Query: 61  KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIF-------------------- 100
            +P  F Y  E+  AYK+  L+ DI  EQKK+  ADLVIF                    
Sbjct: 61  SNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRV 120

Query: 101 ------------------QSKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFC 142
                             Q K A+LS+TTGG+  MY+  G++GD    LWP+Q G LHFC
Sbjct: 121 LCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFC 180

Query: 143 GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPL 183
           GF+VL PQ++++      + R  ++  W +RL+ IW E P+
Sbjct: 181 GFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPI 221


>gi|116256363 transmembrane protease, serine 13 [Homo sapiens]
          Length = 567

 Score = 30.4 bits (67), Expect = 1.4
 Identities = 15/44 (34%), Positives = 21/44 (47%), Gaps = 4/44 (9%)

Query: 132 WPIQS----GILHFCGFQVLEPQLTYSIGHTPADARIQILEGWK 171
           WP Q     G  H CG  +++ Q   +  H     R ++LEGWK
Sbjct: 337 WPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWK 380


>gi|74048554 cancer susceptibility candidate 5 isoform 2 [Homo
            sapiens]
          Length = 2316

 Score = 29.3 bits (64), Expect = 3.1
 Identities = 12/22 (54%), Positives = 15/22 (68%)

Query: 209  EKNKKFGLSVGHHLGKSIPTDN 230
            E+N KFG+  G +LG S P DN
Sbjct: 1184 EENPKFGIGKGKNLGVSFPKDN 1205


>gi|74048514 cancer susceptibility candidate 5 isoform 1 [Homo
            sapiens]
          Length = 2342

 Score = 29.3 bits (64), Expect = 3.1
 Identities = 12/22 (54%), Positives = 15/22 (68%)

Query: 209  EKNKKFGLSVGHHLGKSIPTDN 230
            E+N KFG+  G +LG S P DN
Sbjct: 1210 EENPKFGIGKGKNLGVSFPKDN 1231


>gi|62821787 COBL-like 1 [Homo sapiens]
          Length = 1166

 Score = 28.9 bits (63), Expect = 4.0
 Identities = 21/86 (24%), Positives = 42/86 (48%), Gaps = 8/86 (9%)

Query: 45  MNFNPIISRKDITGKLKDPANFQ-YPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQSK 103
           +N   +    +I  +++ P+N + +  ++ ++YKE HL+   V +QK  + +     ++K
Sbjct: 582 INVEGVAKNNNIDMEVERPSNSEAHETDTAISYKENHLAASSVPDQKLNQPS---AEKTK 638

Query: 104 KAVLSITTGGSGSMYSLQGIHGDMNV 129
            A +  T     S  S  G H D N+
Sbjct: 639 DAAIQTTP----SCNSFDGKHQDHNL 660


>gi|4557303 aldehyde dehydrogenase 3A2 isoform 2 [Homo sapiens]
          Length = 485

 Score = 28.5 bits (62), Expect = 5.3
 Identities = 20/68 (29%), Positives = 29/68 (42%), Gaps = 1/68 (1%)

Query: 128 NVILWPIQSGILHFCGFQVLE-PQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFA 186
           N I+W I+  +  F G  + E P     I        + +LEG K       DE   Y A
Sbjct: 255 NQIVWKIKETVKEFYGENIKESPDYERIINLRHFKRILSLLEGQKIAFGGETDEATRYIA 314

Query: 187 PSSLFDLN 194
           P+ L D++
Sbjct: 315 PTVLTDVD 322


>gi|73466520 aldehyde dehydrogenase 3A2 isoform 1 [Homo sapiens]
          Length = 508

 Score = 28.5 bits (62), Expect = 5.3
 Identities = 20/68 (29%), Positives = 29/68 (42%), Gaps = 1/68 (1%)

Query: 128 NVILWPIQSGILHFCGFQVLE-PQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFA 186
           N I+W I+  +  F G  + E P     I        + +LEG K       DE   Y A
Sbjct: 255 NQIVWKIKETVKEFYGENIKESPDYERIINLRHFKRILSLLEGQKIAFGGETDEATRYIA 314

Query: 187 PSSLFDLN 194
           P+ L D++
Sbjct: 315 PTVLTDVD 322


>gi|4504327 mitochondrial trifunctional protein, beta subunit
           precursor [Homo sapiens]
          Length = 474

 Score = 28.1 bits (61), Expect = 6.9
 Identities = 25/106 (23%), Positives = 48/106 (45%), Gaps = 7/106 (6%)

Query: 13  SERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKLKDPANFQYPAES 72
           +  T  + A + AAA A+ +     +E D YA+  + +  +    G L D   F+ P + 
Sbjct: 219 TSETMGHSADRLAAAFAVSR-----LEQDEYALRSHSLAKKAQDEGLLSDVVPFKVPGKD 273

Query: 73  VLAYKEGHLSPDIVAEQKKLEAADLVIFQSKKAV-LSITTGGSGSM 117
            +  K+  + P  + +  KL+ A +  + +  A   S  T G+ +M
Sbjct: 274 TVT-KDNGIRPSSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAM 318


>gi|170932492 transmembrane protease, serine 5 [Homo sapiens]
          Length = 457

 Score = 28.1 bits (61), Expect = 6.9
 Identities = 14/44 (31%), Positives = 19/44 (43%), Gaps = 4/44 (9%)

Query: 132 WPIQS----GILHFCGFQVLEPQLTYSIGHTPADARIQILEGWK 171
           WP Q+    G  H CG  VL P+   +  H     R+  L  W+
Sbjct: 229 WPWQASVALGFRHTCGGSVLAPRWVVTAAHCMHSFRLARLSSWR 272


>gi|39725717 coiled-coil domain containing 141 [Homo sapiens]
          Length = 875

 Score = 28.1 bits (61), Expect = 6.9
 Identities = 20/87 (22%), Positives = 37/87 (42%), Gaps = 5/87 (5%)

Query: 18  FNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKLKDPANFQYPAESVLAYK 77
           FNY  K   +  LK   +++ + D+YA     +  + +        +   YP++ V    
Sbjct: 350 FNYTKKNEKSRNLKALKYQIQQVDMYAEKMQALKRKMEKVSNKTSDSFLNYPSDKVNVLL 409

Query: 78  EGHLSPDIVAEQKKLEAADLVIFQSKK 104
           E  +  D+   QK ++  D V+   KK
Sbjct: 410 E--VMKDL---QKHVDDFDKVVTDYKK 431


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 27.7 bits (60), Expect = 9.0
 Identities = 15/46 (32%), Positives = 19/46 (41%), Gaps = 9/46 (19%)

Query: 115 GSMYSLQGIHGDMNVILWPIQSGILHFCGFQVLEPQLTYSIGHTPA 160
           G +Y +QG          P      H  G     P L+YS GH+PA
Sbjct: 504 GQLYGVQGE---------PYPGPAAHSQGLPTASPSLSYSTGHSPA 540


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.394 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,607,051
Number of Sequences: 37866
Number of extensions: 362761
Number of successful extensions: 738
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 728
Number of HSP's gapped (non-prelim): 16
length of query: 236
length of database: 18,247,518
effective HSP length: 99
effective length of query: 137
effective length of database: 14,498,784
effective search space: 1986333408
effective search space used: 1986333408
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.