Guide to the Human Genome
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Search of human proteins with 7019323

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7019323 dolichyl-phosphate beta-glucosyltransferase isoform
1 [Homo sapiens]
         (324 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7019323 dolichyl-phosphate beta-glucosyltransferase isoform 1...   650   0.0  
gi|215276969 dolichyl-phosphate beta-glucosyltransferase isoform...   573   e-164
gi|4503363 dolichyl-phosphate mannosyltransferase 1 [Homo sapiens]     73   4e-13
gi|153792095 N-acetylgalactosaminyltransferase 11 [Homo sapiens]       33   0.26 
gi|9966875 calcium/calmodulin-dependent protein kinase ID isofor...    33   0.45 
gi|23943850 calcium/calmodulin-dependent protein kinase ID isofo...    33   0.45 
gi|222446618 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-ac...    32   0.59 
gi|34452725 polypeptide N-acetylgalactosaminyltransferase 4 [Hom...    32   1.0  
gi|4885549 AKT3 kinase isoform 1 [Homo sapiens]                        31   1.3  
gi|32307163 AKT3 kinase isoform 2 [Homo sapiens]                       31   1.3  
gi|21686971 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-ace...    30   2.2  
gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo s...    30   2.9  
gi|14196445 calcium/calmodulin-dependent protein kinase IG [Homo...    30   2.9  
gi|218749848 family with sequence similarity 38, member A [Homo ...    29   5.0  
gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens]            29   5.0  
gi|214010218 semaphorin 4D isoform 1 [Homo sapiens]                    29   6.5  

>gi|7019323 dolichyl-phosphate beta-glucosyltransferase isoform 1
           [Homo sapiens]
          Length = 324

 Score =  650 bits (1676), Expect = 0.0
 Identities = 324/324 (100%), Positives = 324/324 (100%)

Query: 1   MAPLLLQLAVLGAALAAAALVLISIVAFTTATKMPALHRHEEEKFFLNAKGQKETLPSIW 60
           MAPLLLQLAVLGAALAAAALVLISIVAFTTATKMPALHRHEEEKFFLNAKGQKETLPSIW
Sbjct: 1   MAPLLLQLAVLGAALAAAALVLISIVAFTTATKMPALHRHEEEKFFLNAKGQKETLPSIW 60

Query: 61  DSPTKQLSVVVPSYNEEKRLPVMMDEALSYLEKRQKRDPAFTYEVIVVDDGSKDQTSKVA 120
           DSPTKQLSVVVPSYNEEKRLPVMMDEALSYLEKRQKRDPAFTYEVIVVDDGSKDQTSKVA
Sbjct: 61  DSPTKQLSVVVPSYNEEKRLPVMMDEALSYLEKRQKRDPAFTYEVIVVDDGSKDQTSKVA 120

Query: 121 FKYCQKYGSDKVRVITLVKNRGKGGAIRMGIFSSRGEKILMADADGATKFPDVEKLEKGL 180
           FKYCQKYGSDKVRVITLVKNRGKGGAIRMGIFSSRGEKILMADADGATKFPDVEKLEKGL
Sbjct: 121 FKYCQKYGSDKVRVITLVKNRGKGGAIRMGIFSSRGEKILMADADGATKFPDVEKLEKGL 180

Query: 181 NDLQPWPNQMAIACGSRAHLEKESIAQRSYFRTLLMYGFHFLVWFLCVKGIRDTQCGFKL 240
           NDLQPWPNQMAIACGSRAHLEKESIAQRSYFRTLLMYGFHFLVWFLCVKGIRDTQCGFKL
Sbjct: 181 NDLQPWPNQMAIACGSRAHLEKESIAQRSYFRTLLMYGFHFLVWFLCVKGIRDTQCGFKL 240

Query: 241 FTREAASRTFSSLHVERWAFDVELLYIAQFFKIPIAEIAVNWTEIEGSKLVPFWSWLQMG 300
           FTREAASRTFSSLHVERWAFDVELLYIAQFFKIPIAEIAVNWTEIEGSKLVPFWSWLQMG
Sbjct: 241 FTREAASRTFSSLHVERWAFDVELLYIAQFFKIPIAEIAVNWTEIEGSKLVPFWSWLQMG 300

Query: 301 KDLLFIRLRYLTGAWRLEQTRKMN 324
           KDLLFIRLRYLTGAWRLEQTRKMN
Sbjct: 301 KDLLFIRLRYLTGAWRLEQTRKMN 324


>gi|215276969 dolichyl-phosphate beta-glucosyltransferase isoform 2
           [Homo sapiens]
          Length = 294

 Score =  573 bits (1477), Expect = e-164
 Identities = 294/324 (90%), Positives = 294/324 (90%), Gaps = 30/324 (9%)

Query: 1   MAPLLLQLAVLGAALAAAALVLISIVAFTTATKMPALHRHEEEKFFLNAKGQKETLPSIW 60
           MAPLLLQLAVLGAALAAAALVLISIVAFTTATKMPALHRHEEEKFFLNAKGQKETLPSIW
Sbjct: 1   MAPLLLQLAVLGAALAAAALVLISIVAFTTATKMPALHRHEEEKFFLNAKGQKETLPSIW 60

Query: 61  DSPTKQLSVVVPSYNEEKRLPVMMDEALSYLEKRQKRDPAFTYEVIVVDDGSKDQTSKVA 120
           DSPTKQLSVVVPSYNEEKRLPVMMDEALSYLEKRQK                        
Sbjct: 61  DSPTKQLSVVVPSYNEEKRLPVMMDEALSYLEKRQK------------------------ 96

Query: 121 FKYCQKYGSDKVRVITLVKNRGKGGAIRMGIFSSRGEKILMADADGATKFPDVEKLEKGL 180
                 YGSDKVRVITLVKNRGKGGAIRMGIFSSRGEKILMADADGATKFPDVEKLEKGL
Sbjct: 97  ------YGSDKVRVITLVKNRGKGGAIRMGIFSSRGEKILMADADGATKFPDVEKLEKGL 150

Query: 181 NDLQPWPNQMAIACGSRAHLEKESIAQRSYFRTLLMYGFHFLVWFLCVKGIRDTQCGFKL 240
           NDLQPWPNQMAIACGSRAHLEKESIAQRSYFRTLLMYGFHFLVWFLCVKGIRDTQCGFKL
Sbjct: 151 NDLQPWPNQMAIACGSRAHLEKESIAQRSYFRTLLMYGFHFLVWFLCVKGIRDTQCGFKL 210

Query: 241 FTREAASRTFSSLHVERWAFDVELLYIAQFFKIPIAEIAVNWTEIEGSKLVPFWSWLQMG 300
           FTREAASRTFSSLHVERWAFDVELLYIAQFFKIPIAEIAVNWTEIEGSKLVPFWSWLQMG
Sbjct: 211 FTREAASRTFSSLHVERWAFDVELLYIAQFFKIPIAEIAVNWTEIEGSKLVPFWSWLQMG 270

Query: 301 KDLLFIRLRYLTGAWRLEQTRKMN 324
           KDLLFIRLRYLTGAWRLEQTRKMN
Sbjct: 271 KDLLFIRLRYLTGAWRLEQTRKMN 294


>gi|4503363 dolichyl-phosphate mannosyltransferase 1 [Homo sapiens]
          Length = 260

 Score = 72.8 bits (177), Expect = 4e-13
 Identities = 60/236 (25%), Positives = 112/236 (47%), Gaps = 24/236 (10%)

Query: 68  SVVVPSYNEEKRLPVMMDEALSYLEKRQKRDPAFTYEVIVVDDGSKDQTSKVAFKYCQKY 127
           SV++P+YNE + LP+++     +L  +   +    YE+I++DDGS D T  VA +  + Y
Sbjct: 28  SVLLPTYNERENLPLIV-----WLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIY 82

Query: 128 GSDKVRVITLVKNRGKGGAIRMGIFSSRGEKILMADADGA--TKF-PDVEKLEKGLNDLQ 184
           GSD++ +    K  G G A   G+  + G  I++ DAD +   KF P+  + +K  N   
Sbjct: 83  GSDRILLRPREKKLGLGTAYIHGMKHATGNYIIIMDADLSHHPKFIPEFIRKQKEGN--- 139

Query: 185 PWPNQMAIACGSRAHLEKESIAQRSYFRTLLMYGFHFLVWFLCVKGIRDTQCGFKLFTRE 244
                  I  G+R +     +      R ++  G +FL   L   G  D    F+L+ +E
Sbjct: 140 -----FDIVSGTR-YKGNGGVYGWDLKRKIISRGANFLTQILLRPGASDLTGSFRLYRKE 193

Query: 245 AASRTFSSLHVERWAFDVELLYIAQFFKIPIAEIAVNW-------TEIEGSKLVPF 293
              +       + + F +E++  A+     I E+ +++       +++ G+++V F
Sbjct: 194 VLEKLIEKCVSKGYVFQMEMIVRARQLNYTIGEVPISFVDRVYGESKLGGNEIVSF 249


>gi|153792095 N-acetylgalactosaminyltransferase 11 [Homo sapiens]
          Length = 608

 Score = 33.5 bits (75), Expect = 0.26
 Identities = 30/99 (30%), Positives = 43/99 (43%), Gaps = 8/99 (8%)

Query: 68  SVVVPSYNEEKRLPVMMDEALSYLEKRQKRDPA-FTYEVIVVDDGSK-DQTSKVAFKYCQ 125
           SVV+  YNE           L  +     R PA   +E+I+VDD S  D       +Y Q
Sbjct: 154 SVVICFYNEA------FSALLRTVHSVIDRTPAHLLHEIILVDDDSDFDDLKGELDEYVQ 207

Query: 126 KYGSDKVRVITLVKNRGKGGAIRMGIFSSRGEKILMADA 164
           KY   K++VI   K  G      +G   + GE ++  D+
Sbjct: 208 KYLPGKIKVIRNTKREGLIRGRMIGAAHATGEVLVFLDS 246


>gi|9966875 calcium/calmodulin-dependent protein kinase ID isoform 1
           [Homo sapiens]
          Length = 357

 Score = 32.7 bits (73), Expect = 0.45
 Identities = 27/116 (23%), Positives = 51/116 (43%), Gaps = 13/116 (11%)

Query: 148 RMGIFSS--RGEKILMADADGATKFPDVEKLEKGLNDLQPWPNQMAIACGSRAHLEKESI 205
           RMGI     + E +L    D  +K   +   + GL+ ++   + M+ ACG+  ++  E +
Sbjct: 137 RMGIVHRDLKPENLLYYSQDEESK---IMISDFGLSKMEGKGDVMSTACGTPGYVAPEVL 193

Query: 206 AQRSYFRTLLMYGFHFLVWFLCVKGIRDTQCGFKLFTREAASRTFSSLHVERWAFD 261
           AQ+ Y + +  +    + + L         CG+  F  E  S+ F  +    + FD
Sbjct: 194 AQKPYSKAVDCWSIGVIAYILL--------CGYPPFYDENDSKLFEQILKAEYEFD 241


>gi|23943850 calcium/calmodulin-dependent protein kinase ID isoform
           2 [Homo sapiens]
          Length = 385

 Score = 32.7 bits (73), Expect = 0.45
 Identities = 27/116 (23%), Positives = 51/116 (43%), Gaps = 13/116 (11%)

Query: 148 RMGIFSS--RGEKILMADADGATKFPDVEKLEKGLNDLQPWPNQMAIACGSRAHLEKESI 205
           RMGI     + E +L    D  +K   +   + GL+ ++   + M+ ACG+  ++  E +
Sbjct: 137 RMGIVHRDLKPENLLYYSQDEESK---IMISDFGLSKMEGKGDVMSTACGTPGYVAPEVL 193

Query: 206 AQRSYFRTLLMYGFHFLVWFLCVKGIRDTQCGFKLFTREAASRTFSSLHVERWAFD 261
           AQ+ Y + +  +    + + L         CG+  F  E  S+ F  +    + FD
Sbjct: 194 AQKPYSKAVDCWSIGVIAYILL--------CGYPPFYDENDSKLFEQILKAEYEFD 241


>gi|222446618 UDP-N-acetyl-alpha-D-galactosamine:polypeptide
           N-acetylgalactosaminyltransferase-like 4 [Homo sapiens]
          Length = 607

 Score = 32.3 bits (72), Expect = 0.59
 Identities = 29/99 (29%), Positives = 47/99 (47%), Gaps = 7/99 (7%)

Query: 56  LPSIWDSPTKQLSVVVPSYNEEKRLPVMMDEALSYLEKR-----QKRDPAFTYEVIVVDD 110
           LP +  S  + LS    S  E   + + ++EALS L +      ++  P    E+I+VDD
Sbjct: 136 LPDLRPSGCRNLSFP-DSLPEVSIVFIFVNEALSVLLRSIHSAMERTPPHLLKEIILVDD 194

Query: 111 GSKDQTSKVAF-KYCQKYGSDKVRVITLVKNRGKGGAIR 148
            S ++  K    +Y  K  S K   I +V++  + G IR
Sbjct: 195 NSSNEELKEKLTEYVDKVNSQKPGFIKVVRHSKQEGLIR 233


>gi|34452725 polypeptide N-acetylgalactosaminyltransferase 4 [Homo
           sapiens]
          Length = 578

 Score = 31.6 bits (70), Expect = 1.0
 Identities = 38/133 (28%), Positives = 54/133 (40%), Gaps = 21/133 (15%)

Query: 36  ALHRHEEEKFFLNAKGQK---ETLPSIWDSPTKQLSVVVPSYNEEKRLPVMMDEALSYLE 92
           +LHRH E+K     K QK    TLP+         SV++  YNE           L  + 
Sbjct: 111 SLHRHIEDKRMYECKSQKFNYRTLPT--------TSVIIAFYNE------AWSTLLRTIH 156

Query: 93  KRQKRDPA-FTYEVIVVDDGSKDQTSKVAFK-YCQKYGSDKVRVITLVKNRGKGGAIRMG 150
              +  PA    E+I+VDD S     K   + Y      D+VR+I   K  G   A  +G
Sbjct: 157 SVLETSPAVLLKEIILVDDLSDRVYLKTQLETYISNL--DRVRLIRTNKREGLVRARLIG 214

Query: 151 IFSSRGEKILMAD 163
              + G+ +   D
Sbjct: 215 ATFATGDVLTFLD 227


>gi|4885549 AKT3 kinase isoform 1 [Homo sapiens]
          Length = 479

 Score = 31.2 bits (69), Expect = 1.3
 Identities = 34/156 (21%), Positives = 54/156 (34%), Gaps = 35/156 (22%)

Query: 160 LMADADGATKFPDVEKLEKGLNDLQPWPNQMAIACGSRAHLEKESIAQRSYFRTLLMYGF 219
           LM D DG  K  D    ++G+ D       M   CG+  +L  E +    Y R +  +G 
Sbjct: 277 LMLDKDGHIKITDFGLCKEGITDAAT----MKTFCGTPEYLAPEVLEDNDYGRAVDWWGL 332

Query: 220 HFLVWFLCVKGIRDTQCGFKLFTREAASRTFSSLHVERWAF------DVELLYIAQFFKI 273
             +++        +  CG   F  +   + F  + +E   F      D + L      K 
Sbjct: 333 GVVMY--------EMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKD 384

Query: 274 PIAEIA-----------------VNWTEIEGSKLVP 292
           P   +                  VNW ++   KLVP
Sbjct: 385 PNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP 420


>gi|32307163 AKT3 kinase isoform 2 [Homo sapiens]
          Length = 465

 Score = 31.2 bits (69), Expect = 1.3
 Identities = 34/156 (21%), Positives = 54/156 (34%), Gaps = 35/156 (22%)

Query: 160 LMADADGATKFPDVEKLEKGLNDLQPWPNQMAIACGSRAHLEKESIAQRSYFRTLLMYGF 219
           LM D DG  K  D    ++G+ D       M   CG+  +L  E +    Y R +  +G 
Sbjct: 277 LMLDKDGHIKITDFGLCKEGITDAAT----MKTFCGTPEYLAPEVLEDNDYGRAVDWWGL 332

Query: 220 HFLVWFLCVKGIRDTQCGFKLFTREAASRTFSSLHVERWAF------DVELLYIAQFFKI 273
             +++        +  CG   F  +   + F  + +E   F      D + L      K 
Sbjct: 333 GVVMY--------EMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKD 384

Query: 274 PIAEIA-----------------VNWTEIEGSKLVP 292
           P   +                  VNW ++   KLVP
Sbjct: 385 PNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP 420


>gi|21686971 UDP-N-acetyl-alpha-D-galactosamine:polypeptide
           N-acetylgalactosaminyltransferase-like 5 [Homo sapiens]
          Length = 443

 Score = 30.4 bits (67), Expect = 2.2
 Identities = 26/97 (26%), Positives = 42/97 (43%), Gaps = 5/97 (5%)

Query: 68  SVVVPSYNEEKRLPVMMDEALSYLEKRQKRDPAFTYEVIVVDDGSKDQTSKVAFKYCQKY 127
           S+V+  YNEE         +++ L         F  E+I+VDD SK    K    Y  + 
Sbjct: 137 SIVICFYNEECNALFQTMSSVTNLTPHY-----FLEEIILVDDMSKVDDLKEKLDYHLET 191

Query: 128 GSDKVRVITLVKNRGKGGAIRMGIFSSRGEKILMADA 164
              KV++I   K  G   A  +G   + G+ ++  D+
Sbjct: 192 FRGKVKIIRNKKREGLIRARLIGASHASGDVLVFLDS 228


>gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo
           sapiens]
          Length = 370

 Score = 30.0 bits (66), Expect = 2.9
 Identities = 17/83 (20%), Positives = 38/83 (45%), Gaps = 8/83 (9%)

Query: 179 GLNDLQPWPNQMAIACGSRAHLEKESIAQRSYFRTLLMYGFHFLVWFLCVKGIRDTQCGF 238
           GL+ ++   + ++ ACG+  ++  E +AQ+ Y + +  +    + + L         CG+
Sbjct: 164 GLSKMEDPGSVLSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILL--------CGY 215

Query: 239 KLFTREAASRTFSSLHVERWAFD 261
             F  E  ++ F  +    + FD
Sbjct: 216 PPFYDENDAKLFEQILKAEYEFD 238


>gi|14196445 calcium/calmodulin-dependent protein kinase IG [Homo
           sapiens]
          Length = 476

 Score = 30.0 bits (66), Expect = 2.9
 Identities = 16/72 (22%), Positives = 32/72 (44%), Gaps = 8/72 (11%)

Query: 190 MAIACGSRAHLEKESIAQRSYFRTLLMYGFHFLVWFLCVKGIRDTQCGFKLFTREAASRT 249
           M+ ACG+  ++  E +AQ+ Y + +  +    + + L         CG+  F  E  S+ 
Sbjct: 176 MSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVITYILL--------CGYPPFYEETESKL 227

Query: 250 FSSLHVERWAFD 261
           F  +    + F+
Sbjct: 228 FEKIKEGYYEFE 239


>gi|218749848 family with sequence similarity 38, member A [Homo
           sapiens]
          Length = 2090

 Score = 29.3 bits (64), Expect = 5.0
 Identities = 15/58 (25%), Positives = 24/58 (41%)

Query: 181 NDLQPWPNQMAIACGSRAHLEKESIAQRSYFRTLLMYGFHFLVWFLCVKGIRDTQCGF 238
           + L P P Q   A G+R  L+++ +    YF     Y F   + FL    +   +  F
Sbjct: 525 HQLAPLPAQAVFASGTRQQLDQDLLGCLKYFINFFFYKFGLEICFLMAVNVIGQRMNF 582


>gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens]
          Length = 4265

 Score = 29.3 bits (64), Expect = 5.0
 Identities = 39/177 (22%), Positives = 68/177 (38%), Gaps = 16/177 (9%)

Query: 20   LVLISIVAFTTATKMPALHRHEEEKFFLNAKGQKETLPSIWDSPTKQLS--VVVPSYNEE 77
            L L ++  F++ +     H  E    F + +  +E LP IWD    Q    +V+     +
Sbjct: 3575 LALSNLPTFSSFSSDFVKHLSEFRVIFDSLEPHREPLPGIWDQYLDQFQKLLVLRCLRGD 3634

Query: 78   KRLPVMMDEALSYLEKR------------QKRDPAFTYEVIVVDDGSKDQTSKVAFKYCQ 125
            K    M D   + LE R             K   + T  + V+  G+        F    
Sbjct: 3635 KVTNAMQDFVATNLEPRFIEPQTANLSVVFKDSNSTTPLIFVLSPGTDPAADLYKFAEEM 3694

Query: 126  KYGSDKVRVITLVKNRGKGGAIRMGIFSSRGEKILMADADGATKF-PDVEKLEKGLN 181
            K+ S K+  I+L + +G      M     RG+ +   +   A  + P +E+L + +N
Sbjct: 3695 KF-SKKLSAISLGQGQGPRAEAMMRSSIERGKWVFFQNCHLAPSWMPALERLIEHIN 3750


>gi|214010218 semaphorin 4D isoform 1 [Homo sapiens]
          Length = 862

 Score = 28.9 bits (63), Expect = 6.5
 Identities = 26/94 (27%), Positives = 36/94 (38%), Gaps = 15/94 (15%)

Query: 158 KILMADADGATK-FPDVEKLEKGLNDLQPWPNQMAIACGSRA--------HLEKESIAQR 208
           K+L+A   G++   P V+    G   L P P     +C  +         H EK    + 
Sbjct: 671 KVLVASTQGSSPPTPAVQATSSGAITLPPKPAPTGTSCEPKIVINTVPQLHSEKTMYLKS 730

Query: 209 SYFRTLLMYGFHFLVWFLCV------KGIRDTQC 236
           S  R L+     F V FLC+      KG    QC
Sbjct: 731 SDNRLLMSLFLFFFVLFLCLFFYNCYKGYLPRQC 764


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.136    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,417,423
Number of Sequences: 37866
Number of extensions: 479482
Number of successful extensions: 1032
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1024
Number of HSP's gapped (non-prelim): 16
length of query: 324
length of database: 18,247,518
effective HSP length: 102
effective length of query: 222
effective length of database: 14,385,186
effective search space: 3193511292
effective search space used: 3193511292
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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