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Search of human proteins with 13899253
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13899253 uridine-cytidine kinase 1 isoform a [Homo sapiens]
(277 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13899253 uridine-cytidine kinase 1 isoform a [Homo sapiens] 563 e-161
gi|18699734 uridine-cytidine kinase 2 [Homo sapiens] 359 1e-99
gi|209863022 uridine-cytidine kinase 1 isoform b [Homo sapiens] 340 6e-94
gi|57863312 uridine-cytidine kinase 1-like 1 [Homo sapiens] 209 3e-54
gi|8923530 nicotinamide riboside kinase 1 isoform 1 [Homo sapiens] 35 0.072
gi|189027124 nicotinamide riboside kinase 1 isoform 2 [Homo sapi... 34 0.12
gi|46048234 nucleolar protein 8 [Homo sapiens] 32 0.61
gi|239757142 PREDICTED: hypothetical protein [Homo sapiens] 32 0.80
gi|239751665 PREDICTED: hypothetical protein XP_002347963 [Homo ... 32 0.80
gi|239746171 PREDICTED: hypothetical protein XP_002343683 [Homo ... 32 0.80
gi|19743898 receptor tyrosine kinase-like orphan receptor 2 prec... 30 1.8
gi|209915597 UMP-CMP kinase 1 isoform b [Homo sapiens] 30 3.0
gi|191252797 dephospho-CoA kinase domain containing [Homo sapiens] 30 3.0
gi|191252795 dephospho-CoA kinase domain containing [Homo sapiens] 30 3.0
gi|24762248 integrin beta 1 binding protein 3 [Homo sapiens] 29 3.9
gi|4502011 adenylate kinase 1 [Homo sapiens] 29 5.2
gi|28144897 adenylate kinase 5 isoform 1 [Homo sapiens] 29 5.2
gi|28144899 adenylate kinase 5 isoform 2 [Homo sapiens] 29 5.2
gi|239753264 PREDICTED: hypothetical protein [Homo sapiens] 28 8.8
gi|239747823 PREDICTED: hypothetical protein XP_002348330 [Homo ... 28 8.8
gi|239741693 PREDICTED: hypothetical protein XP_002342282 [Homo ... 28 8.8
gi|7706497 UMP-CMP kinase 1 isoform a [Homo sapiens] 28 8.8
>gi|13899253 uridine-cytidine kinase 1 isoform a [Homo sapiens]
Length = 277
Score = 563 bits (1450), Expect = e-161
Identities = 277/277 (100%), Positives = 277/277 (100%)
Query: 1 MASAGGEDCESPAPEADRPHQRPFLIGVSGGTASGKSTVCEKIMELLGQNEVEQRQRKVV 60
MASAGGEDCESPAPEADRPHQRPFLIGVSGGTASGKSTVCEKIMELLGQNEVEQRQRKVV
Sbjct: 1 MASAGGEDCESPAPEADRPHQRPFLIGVSGGTASGKSTVCEKIMELLGQNEVEQRQRKVV 60
Query: 61 ILSQDRFYKVLTAEQKAKALKGQYNFDHPDAFDNDLMHRTLKNIVEGKTVEVPTYDFVTH 120
ILSQDRFYKVLTAEQKAKALKGQYNFDHPDAFDNDLMHRTLKNIVEGKTVEVPTYDFVTH
Sbjct: 61 ILSQDRFYKVLTAEQKAKALKGQYNFDHPDAFDNDLMHRTLKNIVEGKTVEVPTYDFVTH 120
Query: 121 SRLPETTVVYPADVVLFEGILVFYSQEIRDMFHLRLFVDTDSDVRLSRRVLRDVRRGRDL 180
SRLPETTVVYPADVVLFEGILVFYSQEIRDMFHLRLFVDTDSDVRLSRRVLRDVRRGRDL
Sbjct: 121 SRLPETTVVYPADVVLFEGILVFYSQEIRDMFHLRLFVDTDSDVRLSRRVLRDVRRGRDL 180
Query: 181 EQILTQYTTFVKPAFEEFCLPTKKYADVIIPRGVDNMVAINLIVQHIQDILNGDICKWHR 240
EQILTQYTTFVKPAFEEFCLPTKKYADVIIPRGVDNMVAINLIVQHIQDILNGDICKWHR
Sbjct: 181 EQILTQYTTFVKPAFEEFCLPTKKYADVIIPRGVDNMVAINLIVQHIQDILNGDICKWHR 240
Query: 241 GGSNGRSYKRTFSEPGDHPGMLTSGKRSHLESSSRPH 277
GGSNGRSYKRTFSEPGDHPGMLTSGKRSHLESSSRPH
Sbjct: 241 GGSNGRSYKRTFSEPGDHPGMLTSGKRSHLESSSRPH 277
>gi|18699734 uridine-cytidine kinase 2 [Homo sapiens]
Length = 261
Score = 359 bits (922), Expect = 1e-99
Identities = 186/256 (72%), Positives = 211/256 (82%), Gaps = 15/256 (5%)
Query: 23 PFLIGVSGGTASGKSTVCEKIMELLGQNEVEQRQRKVVILSQDRFYKVLTAEQKAKALKG 82
PFLIGVSGGTASGKS+VC KI++LLGQNEV+ RQ++VVILSQD FY+VLT+EQKAKALKG
Sbjct: 20 PFLIGVSGGTASGKSSVCAKIVQLLGQNEVDYRQKQVVILSQDSFYRVLTSEQKAKALKG 79
Query: 83 QYNFDHPDAFDNDLMHRTLKNIVEGKTVEVPTYDFVTHSRLPETTVVYPADVVLFEGILV 142
Q+NFDHPDAFDN+L+ +TLK I EGKTV++P YDFV+HSR ET VYPADVVLFEGIL
Sbjct: 80 QFNFDHPDAFDNELILKTLKEITEGKTVQIPVYDFVSHSRKEETVTVYPADVVLFEGILA 139
Query: 143 FYSQEIRDMFHLRLFVDTDSDVRLSRRVLRDV-RRGRDLEQILTQYTTFVKPAFEEFCLP 201
FYSQE+RD+F ++LFVDTD+D RLSRRVLRD+ RGRDLEQIL+QY TFVKPAFEEFCLP
Sbjct: 140 FYSQEVRDLFQMKLFVDTDADTRLSRRVLRDISERGRDLEQILSQYITFVKPAFEEFCLP 199
Query: 202 TKKYADVIIPRGVDNMVAINLIVQHIQDILNGDICKWHRGGSNGRSYKRTFSEPGDHPGM 261
TKKYADVIIPRG DN+VAINLIVQHIQDILNG G S ++T G G
Sbjct: 200 TKKYADVIIPRGADNLVAINLIVQHIQDILNG-----------GPSKRQT---NGCLNGY 245
Query: 262 LTSGKRSHLESSSRPH 277
S KR ESSSRPH
Sbjct: 246 TPSRKRQASESSSRPH 261
>gi|209863022 uridine-cytidine kinase 1 isoform b [Homo sapiens]
Length = 201
Score = 340 bits (873), Expect = 6e-94
Identities = 169/169 (100%), Positives = 169/169 (100%)
Query: 1 MASAGGEDCESPAPEADRPHQRPFLIGVSGGTASGKSTVCEKIMELLGQNEVEQRQRKVV 60
MASAGGEDCESPAPEADRPHQRPFLIGVSGGTASGKSTVCEKIMELLGQNEVEQRQRKVV
Sbjct: 1 MASAGGEDCESPAPEADRPHQRPFLIGVSGGTASGKSTVCEKIMELLGQNEVEQRQRKVV 60
Query: 61 ILSQDRFYKVLTAEQKAKALKGQYNFDHPDAFDNDLMHRTLKNIVEGKTVEVPTYDFVTH 120
ILSQDRFYKVLTAEQKAKALKGQYNFDHPDAFDNDLMHRTLKNIVEGKTVEVPTYDFVTH
Sbjct: 61 ILSQDRFYKVLTAEQKAKALKGQYNFDHPDAFDNDLMHRTLKNIVEGKTVEVPTYDFVTH 120
Query: 121 SRLPETTVVYPADVVLFEGILVFYSQEIRDMFHLRLFVDTDSDVRLSRR 169
SRLPETTVVYPADVVLFEGILVFYSQEIRDMFHLRLFVDTDSDVRLSRR
Sbjct: 121 SRLPETTVVYPADVVLFEGILVFYSQEIRDMFHLRLFVDTDSDVRLSRR 169
>gi|57863312 uridine-cytidine kinase 1-like 1 [Homo sapiens]
Length = 548
Score = 209 bits (531), Expect = 3e-54
Identities = 103/209 (49%), Positives = 146/209 (69%), Gaps = 8/209 (3%)
Query: 24 FLIGVSGGTASGKSTVCEKIMELLGQNEVEQRQRKVVILSQDRFYKVLTAEQKAKALKGQ 83
F IG+ GG+ASGK+TV I+E L V V+LS D FYKVLT +Q+ +A
Sbjct: 99 FAIGLGGGSASGKTTVARMIIEALDVPWV-------VLLSMDSFYKVLTEQQQEQAAHNN 151
Query: 84 YNFDHPDAFDNDLMHRTLKNIVEGKTVEVPTYDFVTHSRLPETTVVYPADVVLFEGILVF 143
+NFDHPDAFD DL+ TLK + +GK+V+VP YDF THSR + +Y A+V++FEGI+ F
Sbjct: 152 FNFDHPDAFDFDLIISTLKKLKQGKSVKVPIYDFTTHSRKKDWKTLYGANVIIFEGIMAF 211
Query: 144 YSQEIRDMFHLRLFVDTDSDVRLSRRVLRDV-RRGRDLEQILTQYTTFVKPAFEEFCLPT 202
+ + ++ +++FVDTDSD+RL RR+ RD+ RGRD+E ++ QY FVKP+F+++ PT
Sbjct: 212 ADKTLLELLDMKIFVDTDSDIRLVRRLRRDISERGRDIEGVIKQYNKFVKPSFDQYIQPT 271
Query: 203 KKYADVIIPRGVDNMVAINLIVQHIQDIL 231
+ AD+++PRG N VAI+LIVQH+ L
Sbjct: 272 MRLADIVVPRGSGNTVAIDLIVQHVHSQL 300
>gi|8923530 nicotinamide riboside kinase 1 isoform 1 [Homo sapiens]
Length = 199
Score = 35.0 bits (79), Expect = 0.072
Identities = 34/151 (22%), Positives = 66/151 (43%), Gaps = 20/151 (13%)
Query: 22 RPFLIGVSGGTASGKSTVCEKIMELLGQNEVEQRQRKVVILSQDRFYKVLTAEQKAKALK 81
+ F+IG+SG T SGK+T+ + + + L V +SQD F+K + + K
Sbjct: 2 KTFIIGISGVTNSGKTTLAKNLQKHLPNCSV---------ISQDDFFKPESEIETDK--N 50
Query: 82 GQYNFDHPDAFDNDLMHRTLKNIVEGKTVEVPTYDFVTHSRLPETTVVYPADVVLFEGIL 141
G +D +A + + M + +E V + D + +P +++ EG L
Sbjct: 51 GFLQYDVLEALNMEKMMSAISCWMESARHSVVSTDQESAEEIP---------ILIIEGFL 101
Query: 142 VFYSQEIRDMFHLRLFVDTDSDVRLSRRVLR 172
+F + + +++ F+ + RR R
Sbjct: 102 LFNYKPLDTIWNRSYFLTIPYEECKRRRSTR 132
>gi|189027124 nicotinamide riboside kinase 1 isoform 2 [Homo
sapiens]
Length = 175
Score = 34.3 bits (77), Expect = 0.12
Identities = 30/122 (24%), Positives = 55/122 (45%), Gaps = 20/122 (16%)
Query: 22 RPFLIGVSGGTASGKSTVCEKIMELLGQNEVEQRQRKVVILSQDRFYKVLTAEQKAKALK 81
+ F+IG+SG T SGK+T+ + + + L V +SQD F+K + + K
Sbjct: 2 KTFIIGISGVTNSGKTTLAKNLQKHLPNCSV---------ISQDDFFKPESEIETDK--N 50
Query: 82 GQYNFDHPDAFDNDLMHRTLKNIVEGKTVEVPTYDFVTHSRLPETTVVYPADVVLFEGIL 141
G +D +A + + M + +E V + D + +P +++ EG L
Sbjct: 51 GFLQYDVLEALNMEKMMSAISCWMESARHSVVSTDQESAEEIP---------ILIIEGFL 101
Query: 142 VF 143
+F
Sbjct: 102 LF 103
>gi|46048234 nucleolar protein 8 [Homo sapiens]
Length = 1167
Score = 32.0 bits (71), Expect = 0.61
Identities = 24/99 (24%), Positives = 45/99 (45%), Gaps = 16/99 (16%)
Query: 20 HQRPFLIGVSGGT-----ASGKSTVCEKIMELLGQNEVEQRQRKVVILSQDRFYKVLTAE 74
H+ P +I + G+ + G+ T C+ + G N ++ ++R+ SQDR ++
Sbjct: 605 HEDPSIISMEDGSPYVNGSLGEVTPCQHAKKANGPNYIQPQKRQTTFESQDRKAVSPSSS 664
Query: 75 QK------AKALKGQYNFD-----HPDAFDNDLMHRTLK 102
+K ++ L+G+ + H FD D H T K
Sbjct: 665 EKRSKNPISRPLEGKKSLSLSAKTHNIGFDKDSCHSTTK 703
>gi|239757142 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 31.6 bits (70), Expect = 0.80
Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 19/84 (22%)
Query: 207 DVIIPRGVDNMVAINLIVQHIQDILN---------------GDICKWH-RGGSNGRSYKR 250
D +P + N+VA++ I+Q + + L G + W RGG N RS++
Sbjct: 99 DAAVPGFLANVVALDHILQ-VGEFLGKDPFQLVVIDPGVGVGQLLAWRTRGGGNARSFQV 157
Query: 251 TFSEPGDHPGMLTSGKRSHLESSS 274
S+P HP LT + +HL S
Sbjct: 158 LVSKPRTHPVSLT--RLTHLRELS 179
>gi|239751665 PREDICTED: hypothetical protein XP_002347963 [Homo
sapiens]
Length = 379
Score = 31.6 bits (70), Expect = 0.80
Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 19/84 (22%)
Query: 207 DVIIPRGVDNMVAINLIVQHIQDILN---------------GDICKWH-RGGSNGRSYKR 250
D +P + N+VA++ I+Q + + L G + W RGG N RS++
Sbjct: 99 DAAVPGFLANVVALDHILQ-VGEFLGKDPFQLVVIDPGVGVGQLLAWRTRGGGNARSFQV 157
Query: 251 TFSEPGDHPGMLTSGKRSHLESSS 274
S+P HP LT + +HL S
Sbjct: 158 LVSKPRTHPVSLT--RLTHLRELS 179
>gi|239746171 PREDICTED: hypothetical protein XP_002343683 [Homo
sapiens]
Length = 379
Score = 31.6 bits (70), Expect = 0.80
Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 19/84 (22%)
Query: 207 DVIIPRGVDNMVAINLIVQHIQDILN---------------GDICKWH-RGGSNGRSYKR 250
D +P + N+VA++ I+Q + + L G + W RGG N RS++
Sbjct: 99 DAAVPGFLANVVALDHILQ-VGEFLGKDPFQLVVIDPGVGVGQLLAWRTRGGGNARSFQV 157
Query: 251 TFSEPGDHPGMLTSGKRSHLESSS 274
S+P HP LT + +HL S
Sbjct: 158 LVSKPRTHPVSLT--RLTHLRELS 179
>gi|19743898 receptor tyrosine kinase-like orphan receptor 2
precursor [Homo sapiens]
Length = 943
Score = 30.4 bits (67), Expect = 1.8
Identities = 26/92 (28%), Positives = 41/92 (44%)
Query: 44 MELLGQNEVEQRQRKVVILSQDRFYKVLTAEQKAKALKGQYNFDHPDAFDNDLMHRTLKN 103
ME+ N+ +Q + K + LS RF + L ++ K KG P + +TLK+
Sbjct: 452 MEMPLINQHKQAKLKEISLSAVRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKD 511
Query: 104 IVEGKTVEVPTYDFVTHSRLPETTVVYPADVV 135
EG E ++ + +RL VV VV
Sbjct: 512 KAEGPLREEFRHEAMLRARLQHPNVVCLLGVV 543
>gi|209915597 UMP-CMP kinase 1 isoform b [Homo sapiens]
Length = 179
Score = 29.6 bits (65), Expect = 3.0
Identities = 12/41 (29%), Positives = 22/41 (53%)
Query: 22 RPFLIGVSGGTASGKSTVCEKIMELLGQNEVEQRQRKVVIL 62
+P ++ V GG +GK T C +I+E + Q Q+ ++
Sbjct: 34 KPLVVFVLGGPGAGKGTQCARIVEEMDQTMAANAQKNKFLI 74
>gi|191252797 dephospho-CoA kinase domain containing [Homo
sapiens]
Length = 231
Score = 29.6 bits (65), Expect = 3.0
Identities = 12/23 (52%), Positives = 18/23 (78%)
Query: 24 FLIGVSGGTASGKSTVCEKIMEL 46
FL+G++GG ASGKS+V + +L
Sbjct: 2 FLVGLTGGIASGKSSVIQVFQQL 24
>gi|191252795 dephospho-CoA kinase domain containing [Homo
sapiens]
Length = 231
Score = 29.6 bits (65), Expect = 3.0
Identities = 12/23 (52%), Positives = 18/23 (78%)
Query: 24 FLIGVSGGTASGKSTVCEKIMEL 46
FL+G++GG ASGKS+V + +L
Sbjct: 2 FLVGLTGGIASGKSSVIQVFQQL 24
>gi|24762248 integrin beta 1 binding protein 3 [Homo sapiens]
Length = 230
Score = 29.3 bits (64), Expect = 3.9
Identities = 29/149 (19%), Positives = 60/149 (40%), Gaps = 17/149 (11%)
Query: 25 LIGVSGGTASGKSTVCEKIMELLGQNEVEQRQRKVVILSQDRFYKVLTAEQKAKALKGQY 84
++G+ G T GK+T+ ++ L ++ QD F+K +Q A G
Sbjct: 4 IVGIGGMTNGGKTTLTNSLLRAL---------PNCCVIHQDDFFK--PQDQIAVGEDGFK 52
Query: 85 NFDHPDAFDNDLMHRTLKNIVEGKTVEVPTYDFVTHSRLPETTVVYPADVVLFEGILVFY 144
+D ++ D + M T++ + + +T ++L EG L++
Sbjct: 53 QWDVLESLDMEAMLDTVQAWLSSPQKFARAHGVSVQPEASDT------HILLLEGFLLYS 106
Query: 145 SQEIRDMFHLRLFVDTDSDVRLSRRVLRD 173
+ + D++ R F+ + RR R+
Sbjct: 107 YKPLVDLYSRRYFLTVPYEECKWRRSTRN 135
>gi|4502011 adenylate kinase 1 [Homo sapiens]
Length = 194
Score = 28.9 bits (63), Expect = 5.2
Identities = 13/24 (54%), Positives = 16/24 (66%)
Query: 25 LIGVSGGTASGKSTVCEKIMELLG 48
+I V GG SGK T CEKI++ G
Sbjct: 10 IIFVVGGPGSGKGTQCEKIVQKYG 33
>gi|28144897 adenylate kinase 5 isoform 1 [Homo sapiens]
Length = 562
Score = 28.9 bits (63), Expect = 5.2
Identities = 12/24 (50%), Positives = 16/24 (66%)
Query: 25 LIGVSGGTASGKSTVCEKIMELLG 48
+I + GG SGK T CEK++E G
Sbjct: 378 IIFIIGGPGSGKGTQCEKLVEKYG 401
>gi|28144899 adenylate kinase 5 isoform 2 [Homo sapiens]
Length = 536
Score = 28.9 bits (63), Expect = 5.2
Identities = 12/24 (50%), Positives = 16/24 (66%)
Query: 25 LIGVSGGTASGKSTVCEKIMELLG 48
+I + GG SGK T CEK++E G
Sbjct: 352 IIFIIGGPGSGKGTQCEKLVEKYG 375
>gi|239753264 PREDICTED: hypothetical protein [Homo sapiens]
Length = 480
Score = 28.1 bits (61), Expect = 8.8
Identities = 15/40 (37%), Positives = 19/40 (47%), Gaps = 2/40 (5%)
Query: 209 IIPRGVDNMVAINLIVQH--IQDILNGDICKWHRGGSNGR 246
I G + A+ L+V H D+LNG C W G GR
Sbjct: 21 ITEHGREPRKAVLLVVVHHVFGDLLNGRKCSWEVNGKEGR 60
>gi|239747823 PREDICTED: hypothetical protein XP_002348330 [Homo
sapiens]
Length = 444
Score = 28.1 bits (61), Expect = 8.8
Identities = 15/40 (37%), Positives = 19/40 (47%), Gaps = 2/40 (5%)
Query: 209 IIPRGVDNMVAINLIVQH--IQDILNGDICKWHRGGSNGR 246
I G + A+ L+V H D+LNG C W G GR
Sbjct: 21 ITEHGREPRKAVLLVVVHHVFGDLLNGRKCSWEVNGKEGR 60
>gi|239741693 PREDICTED: hypothetical protein XP_002342282 [Homo
sapiens]
Length = 480
Score = 28.1 bits (61), Expect = 8.8
Identities = 15/40 (37%), Positives = 19/40 (47%), Gaps = 2/40 (5%)
Query: 209 IIPRGVDNMVAINLIVQH--IQDILNGDICKWHRGGSNGR 246
I G + A+ L+V H D+LNG C W G GR
Sbjct: 21 ITEHGREPRKAVLLVVVHHVFGDLLNGRKCSWEVNGKEGR 60
>gi|7706497 UMP-CMP kinase 1 isoform a [Homo sapiens]
Length = 228
Score = 28.1 bits (61), Expect = 8.8
Identities = 11/27 (40%), Positives = 17/27 (62%)
Query: 22 RPFLIGVSGGTASGKSTVCEKIMELLG 48
+P ++ V GG +GK T C +I+E G
Sbjct: 34 KPLVVFVLGGPGAGKGTQCARIVEKYG 60
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,948,754
Number of Sequences: 37866
Number of extensions: 474974
Number of successful extensions: 1116
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1097
Number of HSP's gapped (non-prelim): 24
length of query: 277
length of database: 18,247,518
effective HSP length: 101
effective length of query: 176
effective length of database: 14,423,052
effective search space: 2538457152
effective search space used: 2538457152
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.