Search of human proteins with 68508955

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens]
         (786 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens]          1630   0.0  
gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens]          1607   0.0  
gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens]          1333   0.0  
gi|23397683 egf-like module containing, mucin-like, hormone rece...   941   0.0  
gi|23397691 egf-like module containing, mucin-like, hormone rece...   922   0.0  
gi|23397681 egf-like module containing, mucin-like, hormone rece...   918   0.0  
gi|23397689 egf-like module containing, mucin-like, hormone rece...   899   0.0  
gi|23397685 egf-like module containing, mucin-like, hormone rece...   657   0.0  
gi|23397693 egf-like module containing, mucin-like, hormone rece...   638   0.0  
gi|23397687 egf-like module containing, mucin-like, hormone rece...   550   e-156
gi|40807489 egf-like module containing, mucin-like, hormone rece...   412   e-115
gi|133930786 egf-like module-containing mucin-like receptor 3 [H...   309   6e-84
gi|6912464 latrophilin 2 precursor [Homo sapiens]                     294   2e-79
gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]          291   1e-78
gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]          291   1e-78
gi|148806925 EGF, latrophilin and seven transmembrane domain con...   291   2e-78
gi|163792198 latrophilin 3 precursor [Homo sapiens]                   280   3e-75
gi|45433552 G protein-coupled receptor 133 [Homo sapiens]             191   2e-48
gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo s...   189   7e-48
gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo ...   166   8e-41
gi|223556012 G-protein coupled receptor 113 isoform 1 [Homo sapi...   159   9e-39
gi|223556014 G-protein coupled receptor 113 isoform 2 [Homo sapi...   159   9e-39
gi|141802362 G-protein coupled receptor 113 isoform 3 [Homo sapi...   159   9e-39
gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo...   158   2e-38
gi|119943125 G protein-coupled receptor 64 isoform 3 [Homo sapiens]   154   2e-37
gi|119943116 G protein-coupled receptor 64 isoform 2 [Homo sapiens]   154   2e-37
gi|119943120 G protein-coupled receptor 64 isoform 1 [Homo sapiens]   154   2e-37
gi|119943129 G protein-coupled receptor 64 isoform 4 [Homo sapiens]   154   2e-37
gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [...   150   4e-36
gi|59710093 G-protein coupled receptor 112 [Homo sapiens]             148   2e-35

>gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens]
          Length = 786

 Score = 1630 bits (4221), Expect = 0.0
 Identities = 786/786 (100%), Positives = 786/786 (100%)

Query: 1   MGGRVFLAFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTE 60
           MGGRVFLAFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTE
Sbjct: 1   MGGRVFLAFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTE 60

Query: 61  TCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDEC 120
           TCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDEC
Sbjct: 61  TCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDEC 120

Query: 121 QQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVDECSSGQHQCDSSTVCFNT 180
           QQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVDECSSGQHQCDSSTVCFNT
Sbjct: 121 QQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVDECSSGQHQCDSSTVCFNT 180

Query: 181 VGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDS 240
           VGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDS
Sbjct: 181 VGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDS 240

Query: 241 KTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGP 300
           KTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGP
Sbjct: 241 KTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGP 300

Query: 301 FTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTT 360
           FTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTT
Sbjct: 301 FTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTT 360

Query: 361 LLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHL 420
           LLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHL
Sbjct: 361 LLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHL 420

Query: 421 ESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSH 480
           ESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSH
Sbjct: 421 ESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSH 480

Query: 481 LSSFAILMAHYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCIC 540
           LSSFAILMAHYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCIC
Sbjct: 481 LSSFAILMAHYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCIC 540

Query: 541 LFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQG 600
           LFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQG
Sbjct: 541 LFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQG 600

Query: 601 LSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAV 660
           LSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAV
Sbjct: 601 LSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAV 660

Query: 661 IFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTY 720
           IFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTY
Sbjct: 661 IFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTY 720

Query: 721 VFTILNCLQGAFLYLLHCLLNKKVREEYRKWACLVAGGSKYSEFTSTTSGTGHNQTRALR 780
           VFTILNCLQGAFLYLLHCLLNKKVREEYRKWACLVAGGSKYSEFTSTTSGTGHNQTRALR
Sbjct: 721 VFTILNCLQGAFLYLLHCLLNKKVREEYRKWACLVAGGSKYSEFTSTTSGTGHNQTRALR 780

Query: 781 ASESGI 786
           ASESGI
Sbjct: 781 ASESGI 786


>gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens]
          Length = 835

 Score = 1607 bits (4161), Expect = 0.0
 Identities = 786/835 (94%), Positives = 786/835 (94%), Gaps = 49/835 (5%)

Query: 1   MGGRVFLAFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTE 60
           MGGRVFLAFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTE
Sbjct: 1   MGGRVFLAFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTE 60

Query: 61  TCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDEC 120
           TCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDEC
Sbjct: 61  TCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDEC 120

Query: 121 QQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDV------------------- 161
           QQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDV                   
Sbjct: 121 QQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNN 180

Query: 162 ------------------------------DECSSGQHQCDSSTVCFNTVGSYSCRCRPG 191
                                         DECSSGQHQCDSSTVCFNTVGSYSCRCRPG
Sbjct: 181 VGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPG 240

Query: 192 WKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVTIQN 251
           WKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVTIQN
Sbjct: 241 WKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVTIQN 300

Query: 252 VIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSNTEL 311
           VIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSNTEL
Sbjct: 301 VIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSNTEL 360

Query: 312 TLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLNLHS 371
           TLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLNLHS
Sbjct: 361 TLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLNLHS 420

Query: 372 KKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDP 431
           KKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDP
Sbjct: 421 KKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDP 480

Query: 432 PAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHY 491
           PAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHY
Sbjct: 481 PAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHY 540

Query: 492 DVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAG 551
           DVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAG
Sbjct: 541 DVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAG 600

Query: 552 IENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGY 611
           IENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGY
Sbjct: 601 IENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGY 660

Query: 612 GVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQ 671
           GVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQ
Sbjct: 661 GVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQ 720

Query: 672 KFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGA 731
           KFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGA
Sbjct: 721 KFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGA 780

Query: 732 FLYLLHCLLNKKVREEYRKWACLVAGGSKYSEFTSTTSGTGHNQTRALRASESGI 786
           FLYLLHCLLNKKVREEYRKWACLVAGGSKYSEFTSTTSGTGHNQTRALRASESGI
Sbjct: 781 FLYLLHCLLNKKVREEYRKWACLVAGGSKYSEFTSTTSGTGHNQTRALRASESGI 835


>gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens]
          Length = 742

 Score = 1333 bits (3450), Expect = 0.0
 Identities = 676/794 (85%), Positives = 686/794 (86%), Gaps = 60/794 (7%)

Query: 1   MGGRVFLAFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTE 60
           MGGRVFLAFCVWLTL                                          P  
Sbjct: 1   MGGRVFLAFCVWLTL------------------------------------------PGA 18

Query: 61  TCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDEC 120
              D   CA      C + S C N      C C+PG+   S   T   E   TC D++EC
Sbjct: 19  ETQDSRGCAR----WCPQNSSCVNATA---CRCNPGFSSFSEIITTPTE---TCDDINEC 68

Query: 121 QQNPRL-CKSYGTCVNTLGSYTCQCLPGFK-------FIPEDPKVCTDVDECSSGQHQCD 172
               ++ C  +  C NT GSY C C PG++       F  E    C DVDECSSGQHQCD
Sbjct: 69  ATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECSSGQHQCD 128

Query: 173 SSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDK 232
           SSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDK
Sbjct: 129 SSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDK 188

Query: 233 VQDLGRDSKTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRIL 292
           VQDLGRDSKTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRIL
Sbjct: 189 VQDLGRDSKTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRIL 248

Query: 293 AKSLPKGPFTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGI 352
           AKSLPKGPFTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGI
Sbjct: 249 AKSLPKGPFTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGI 308

Query: 353 LSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSP 412
           LSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSP
Sbjct: 309 LSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSP 368

Query: 413 ILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNG 472
           ILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNG
Sbjct: 369 ILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNG 428

Query: 473 STTCQCSHLSSFAILMAHYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTT 532
           STTCQCSHLSSFAILMAHYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTT
Sbjct: 429 STTCQCSHLSSFAILMAHYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTT 488

Query: 533 IHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLV 592
           IHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLV
Sbjct: 489 IHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLV 548

Query: 593 VRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVT 652
           VRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVT
Sbjct: 549 VRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVT 608

Query: 653 FIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFD 712
           FIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFD
Sbjct: 609 FIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFD 668

Query: 713 DRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWACLVAGGSKYSEFTSTTSGTG 772
           DRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWACLVAGGSKYSEFTSTTSGTG
Sbjct: 669 DRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWACLVAGGSKYSEFTSTTSGTG 728

Query: 773 HNQTRALRASESGI 786
           HNQTRALRASESGI
Sbjct: 729 HNQTRALRASESGI 742


>gi|23397683 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform b [Homo sapiens]
          Length = 774

 Score =  941 bits (2433), Expect = 0.0
 Identities = 459/762 (60%), Positives = 561/762 (73%), Gaps = 28/762 (3%)

Query: 1   MGGRVFL---AFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITT 57
           MGGRVFL   AFCVWLTLPGAETQDSRGCARWCPQ+SSCVNATACRCNPGFSSFSEIITT
Sbjct: 1   MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITT 60

Query: 58  PTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 117
           P ETCDDINECAT SKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV
Sbjct: 61  PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 120

Query: 118 DECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVDECSSGQHQCDSSTVC 177
           DECQQNPRLCKSYGTCVNTLGSYTCQCLPGFK  PEDPK+CTDVDECSSGQHQCDSSTVC
Sbjct: 121 DECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVDECSSGQHQCDSSTVC 180

Query: 178 FNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLG 237
           FNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLG
Sbjct: 181 FNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLG 240

Query: 238 RDSKTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLP 297
           RD K   A  TIQ++++ +DEL+EAPGD+E L    +H +A+ LL  LED++R L+K+L 
Sbjct: 241 RDYKPGLANNTIQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLS 300

Query: 298 KGPFTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQN 357
            G   +  P+ TEL+L +Q++ D++VT+ Q+ A M+L+W  A  + DPGP+V G++SI  
Sbjct: 301 NGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQKSGDPGPSVVGLVSIPG 360

Query: 358 MTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAF 417
           M  LLA A L L  +KQ  L E ++  ++      LS V S FLS+N+T+ L+SP+ F F
Sbjct: 361 MGKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDTQNLSSPVTFTF 420

Query: 418 SHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQ 477
           SH              + V+  PRQ++LC FW+   +  GHWAT GC  +G+++ ST C+
Sbjct: 421 SH--------------RSVI--PRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICR 464

Query: 478 CSHLSSFAILMAHYDV--EDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHL 535
           C+HLSSFA+LMAHYDV  ED  LT+IT +GL++SL CLLL  LTFLL + IQ + T++HL
Sbjct: 465 CTHLSSFAVLMAHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHL 524

Query: 536 HLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELY-----F 590
            L +CLF+   +FL  I+  G +V   C ++AG LHY +LA   WM LE L L+      
Sbjct: 525 QLSLCLFLAHLLFLVAIDQTGHKV--LCSIIAGTLHYLYLATLTWMLLEALYLFLTARNL 582

Query: 591 LVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGP 650
            VV          + +  +GYGVP + V +SAA     YG P  CWL  E+GF+W FLGP
Sbjct: 583 TVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGP 642

Query: 651 VTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFI 710
           V  I   N V+F+ T+W L  + S +N ++  L+  R L   A AQLF+LGCTW  G+  
Sbjct: 643 VCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQ 702

Query: 711 FDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWA 752
               + V+ Y+FTI+N LQG F++L++CLL+++VRE+Y KW+
Sbjct: 703 VGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWS 744


>gi|23397691 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform f [Homo sapiens]
          Length = 763

 Score =  922 bits (2383), Expect = 0.0
 Identities = 454/762 (59%), Positives = 553/762 (72%), Gaps = 39/762 (5%)

Query: 1   MGGRVFL---AFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITT 57
           MGGRVFL   AFCVWLTLPGAETQDSRGCARWCPQ+SSCVNATACRCNPGFSSFSEIITT
Sbjct: 1   MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITT 60

Query: 58  PTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 117
           P ETCDDINECAT SKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV
Sbjct: 61  PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 120

Query: 118 DECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVDECSSGQHQCDSSTVC 177
           DECQQNPRLCKSYGTCVNTLGSYTCQCLPGFK  PEDPK+CTDVDECSSGQHQCDSSTVC
Sbjct: 121 DECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVDECSSGQHQCDSSTVC 180

Query: 178 FNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLG 237
           FNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLG
Sbjct: 181 FNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLG 240

Query: 238 RDSKTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLP 297
           RD K   A  TIQ++++ +DEL+EAPGD+E L    +H +A+ LL  LED++R L+K+L 
Sbjct: 241 RDYKPGLANNTIQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLS 300

Query: 298 KGPFTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQN 357
            G   +  P+ TEL+L +Q++ D++VT+ Q+ A M+L+W  A  + DPG           
Sbjct: 301 NGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQKSGDPG----------- 349

Query: 358 MTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAF 417
           M  LLA A L L  +KQ  L E ++  ++      LS V S FLS+N+T+ L+SP+ F F
Sbjct: 350 MGKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDTQNLSSPVTFTF 409

Query: 418 SHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQ 477
           SH              + V+  PRQ++LC FW+   +  GHWAT GC  +G+++ ST C+
Sbjct: 410 SH--------------RSVI--PRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICR 453

Query: 478 CSHLSSFAILMAHYDV--EDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHL 535
           C+HLSSFA+LMAHYDV  ED  LT+IT +GL++SL CLLL  LTFLL + IQ + T++HL
Sbjct: 454 CTHLSSFAVLMAHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHL 513

Query: 536 HLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELY-----F 590
            L +CLF+   +FL  I+  G +V   C ++AG LHY +LA   WM LE L L+      
Sbjct: 514 QLSLCLFLAHLLFLVAIDQTGHKV--LCSIIAGTLHYLYLATLTWMLLEALYLFLTARNL 571

Query: 591 LVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGP 650
            VV          + +  +GYGVP + V +SAA     YG P  CWL  E+GF+W FLGP
Sbjct: 572 TVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGP 631

Query: 651 VTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFI 710
           V  I   N V+F+ T+W L  + S +N ++  L+  R L   A AQLF+LGCTW  G+  
Sbjct: 632 VCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQ 691

Query: 711 FDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWA 752
               + V+ Y+FTI+N LQG F++L++CLL+++VRE+Y KW+
Sbjct: 692 VGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWS 733


>gi|23397681 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform a [Homo sapiens]
          Length = 823

 Score =  918 bits (2373), Expect = 0.0
 Identities = 459/811 (56%), Positives = 561/811 (69%), Gaps = 77/811 (9%)

Query: 1   MGGRVFL---AFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITT 57
           MGGRVFL   AFCVWLTLPGAETQDSRGCARWCPQ+SSCVNATACRCNPGFSSFSEIITT
Sbjct: 1   MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITT 60

Query: 58  PTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 117
           P ETCDDINECAT SKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV
Sbjct: 61  PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 120

Query: 118 DECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDV---------------- 161
           DECQQNPRLCKSYGTCVNTLGSYTCQCLPGFK  PEDPK+CTDV                
Sbjct: 121 DECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHC 180

Query: 162 ---------------------------------DECSSGQHQCDSSTVCFNTVGSYSCRC 188
                                            DECSSGQHQCDSSTVCFNTVGSYSCRC
Sbjct: 181 LNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRC 240

Query: 189 RPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVT 248
           RPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRD K   A  T
Sbjct: 241 RPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDYKPGLANNT 300

Query: 249 IQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSN 308
           IQ++++ +DEL+EAPGD+E L    +H +A+ LL  LED++R L+K+L  G   +  P+ 
Sbjct: 301 IQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLSNGLLNFSYPAG 360

Query: 309 TELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLN 368
           TEL+L +Q++ D++VT+ Q+ A M+L+W  A  + DPGP+V G++SI  M  LLA A L 
Sbjct: 361 TELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQKSGDPGPSVVGLVSIPGMGKLLAEAPLV 420

Query: 369 LHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAG 428
           L  +KQ  L E ++  ++      LS V S FLS+N+T+ L+SP+ F FSH         
Sbjct: 421 LEPEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDTQNLSSPVTFTFSH--------- 471

Query: 429 RDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILM 488
                + V+  PRQ++LC FW+   +  GHWAT GC  +G+++ ST C+C+HLSSFA+LM
Sbjct: 472 -----RSVI--PRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLSSFAVLM 524

Query: 489 AHYDV--EDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGST 546
           AHYDV  ED  LT+IT +GL++SL CLLL  LTFLL + IQ + T++HL L +CLF+   
Sbjct: 525 AHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHL 584

Query: 547 IFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELY-----FLVVRVFQGQGL 601
           +FL  I+  G +V   C ++AG LHY +LA   WM LE L L+       VV        
Sbjct: 585 LFLVAIDQTGHKV--LCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRF 642

Query: 602 STRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVI 661
             + +  +GYGVP + V +SAA     YG P  CWL  E+GF+W FLGPV  I   N V+
Sbjct: 643 MKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSVNLVL 702

Query: 662 FVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYV 721
           F+ T+W L  + S +N ++  L+  R L   A AQLF+LGCTW  G+      + V+ Y+
Sbjct: 703 FLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQVGPAARVMAYL 762

Query: 722 FTILNCLQGAFLYLLHCLLNKKVREEYRKWA 752
           FTI+N LQG F++L++CLL+++VRE+Y KW+
Sbjct: 763 FTIINSLQGVFIFLVYCLLSQQVREQYGKWS 793


>gi|23397689 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform e [Homo sapiens]
          Length = 812

 Score =  899 bits (2323), Expect = 0.0
 Identities = 454/811 (55%), Positives = 553/811 (68%), Gaps = 88/811 (10%)

Query: 1   MGGRVFL---AFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITT 57
           MGGRVFL   AFCVWLTLPGAETQDSRGCARWCPQ+SSCVNATACRCNPGFSSFSEIITT
Sbjct: 1   MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITT 60

Query: 58  PTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 117
           P ETCDDINECAT SKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV
Sbjct: 61  PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 120

Query: 118 DECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDV---------------- 161
           DECQQNPRLCKSYGTCVNTLGSYTCQCLPGFK  PEDPK+CTDV                
Sbjct: 121 DECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHC 180

Query: 162 ---------------------------------DECSSGQHQCDSSTVCFNTVGSYSCRC 188
                                            DECSSGQHQCDSSTVCFNTVGSYSCRC
Sbjct: 181 LNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRC 240

Query: 189 RPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVT 248
           RPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRD K   A  T
Sbjct: 241 RPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDYKPGLANNT 300

Query: 249 IQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSN 308
           IQ++++ +DEL+EAPGD+E L    +H +A+ LL  LED++R L+K+L  G   +  P+ 
Sbjct: 301 IQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLSNGLLNFSYPAG 360

Query: 309 TELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLN 368
           TEL+L +Q++ D++VT+ Q+ A M+L+W  A  + DPG           M  LLA A L 
Sbjct: 361 TELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQKSGDPG-----------MGKLLAEAPLV 409

Query: 369 LHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAG 428
           L  +KQ  L E ++  ++      LS V S FLS+N+T+ L+SP+ F FSH         
Sbjct: 410 LEPEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDTQNLSSPVTFTFSH--------- 460

Query: 429 RDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILM 488
                + V+  PRQ++LC FW+   +  GHWAT GC  +G+++ ST C+C+HLSSFA+LM
Sbjct: 461 -----RSVI--PRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLSSFAVLM 513

Query: 489 AHYDV--EDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGST 546
           AHYDV  ED  LT+IT +GL++SL CLLL  LTFLL + IQ + T++HL L +CLF+   
Sbjct: 514 AHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHL 573

Query: 547 IFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELY-----FLVVRVFQGQGL 601
           +FL  I+  G +V   C ++AG LHY +LA   WM LE L L+       VV        
Sbjct: 574 LFLVAIDQTGHKV--LCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRF 631

Query: 602 STRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVI 661
             + +  +GYGVP + V +SAA     YG P  CWL  E+GF+W FLGPV  I   N V+
Sbjct: 632 MKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSVNLVL 691

Query: 662 FVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYV 721
           F+ T+W L  + S +N ++  L+  R L   A AQLF+LGCTW  G+      + V+ Y+
Sbjct: 692 FLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQVGPAARVMAYL 751

Query: 722 FTILNCLQGAFLYLLHCLLNKKVREEYRKWA 752
           FTI+N LQG F++L++CLL+++VRE+Y KW+
Sbjct: 752 FTIINSLQGVFIFLVYCLLSQQVREQYGKWS 782


>gi|23397685 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform c [Homo sapiens]
          Length = 730

 Score =  657 bits (1696), Expect = 0.0
 Identities = 355/770 (46%), Positives = 465/770 (60%), Gaps = 88/770 (11%)

Query: 1   MGGRVFL---AFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITT 57
           MGGRVFL   AFCVWLTL                                          
Sbjct: 1   MGGRVFLVFLAFCVWLTL------------------------------------------ 18

Query: 58  PTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 117
           P     D   CA      C + S C N      C C+PG+   S   T   E   TC D+
Sbjct: 19  PGAETQDSRGCAR----WCPQDSSCVNATA---CRCNPGFSSFSEIITTPME---TCDDI 68

Query: 118 DECQQNPRL-CKSYGTCVNTLGSYTCQCLPGFK-------FIPEDPKVCTDVDECSSGQH 169
           +EC    ++ C  +  C NT GSY C C PG++       F  E    C DVDECSSGQH
Sbjct: 69  NECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECSSGQH 128

Query: 170 QCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRF 229
           QCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRF
Sbjct: 129 QCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRF 188

Query: 230 FDKVQDLGRDSKTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIM 289
           FDKVQDLGRD K   A  TIQ++++ +DEL+EAPGD+E L    +H +A+ LL  LED++
Sbjct: 189 FDKVQDLGRDYKPGLANNTIQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVL 248

Query: 290 RILAKSLPKGPFTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAV 349
           R L+K+L  G   +  P+ TEL+L +Q++ D++VT+ Q+ A M+L+W  A  + DPGP+V
Sbjct: 249 RGLSKNLSNGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQKSGDPGPSV 308

Query: 350 AGILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKEL 409
            G++SI  M  LLA A L L  +KQ  L E ++  ++      LS V S FLS+N+T+ L
Sbjct: 309 VGLVSIPGMGKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDTQNL 368

Query: 410 NSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGS 469
           +SP+ F FSH              + V+  PRQ++LC FW+   +  GHWAT GC  +G+
Sbjct: 369 SSPVTFTFSH--------------RSVI--PRQKVLCVFWEHGQNGCGHWATTGCSTIGT 412

Query: 470 KNGSTTCQCSHLSSFAILMAHYDV--EDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQ 527
           ++ ST C+C+HLSSFA+LMAHYDV  ED  LT+IT +GL++SL CLLL  LTFLL + IQ
Sbjct: 413 RDTSTICRCTHLSSFAVLMAHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQ 472

Query: 528 GSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLE 587
            + T++HL L +CLF+   +FL  I+  G +V   C ++AG LHY +LA   WM LE L 
Sbjct: 473 NTSTSLHLQLSLCLFLAHLLFLVAIDQTGHKV--LCSIIAGTLHYLYLATLTWMLLEALY 530

Query: 588 LY-----FLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQG 642
           L+       VV          + +  +GYGVP + V +SAA     YG P  CWL  E+G
Sbjct: 531 LFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKG 590

Query: 643 FLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGC 702
           F+W FLGPV  I   N V+F+ T+W L  + S +N ++  L+  R L   A AQLF+LGC
Sbjct: 591 FIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGC 650

Query: 703 TWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWA 752
           TW  G+      + V+ Y+FTI+N LQG F++L++CLL+++VRE+Y KW+
Sbjct: 651 TWCLGILQVGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWS 700


>gi|23397693 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform g [Homo sapiens]
          Length = 719

 Score =  638 bits (1646), Expect = 0.0
 Identities = 350/770 (45%), Positives = 457/770 (59%), Gaps = 99/770 (12%)

Query: 1   MGGRVFL---AFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITT 57
           MGGRVFL   AFCVWLTL                                          
Sbjct: 1   MGGRVFLVFLAFCVWLTL------------------------------------------ 18

Query: 58  PTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 117
           P     D   CA      C + S C N      C C+PG+   S   T   E   TC D+
Sbjct: 19  PGAETQDSRGCAR----WCPQDSSCVNATA---CRCNPGFSSFSEIITTPME---TCDDI 68

Query: 118 DECQQNPRL-CKSYGTCVNTLGSYTCQCLPGFK-------FIPEDPKVCTDVDECSSGQH 169
           +EC    ++ C  +  C NT GSY C C PG++       F  E    C DVDECSSGQH
Sbjct: 69  NECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECSSGQH 128

Query: 170 QCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRF 229
           QCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRF
Sbjct: 129 QCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRF 188

Query: 230 FDKVQDLGRDSKTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIM 289
           FDKVQDLGRD K   A  TIQ++++ +DEL+EAPGD+E L    +H +A+ LL  LED++
Sbjct: 189 FDKVQDLGRDYKPGLANNTIQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVL 248

Query: 290 RILAKSLPKGPFTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAV 349
           R L+K+L  G   +  P+ TEL+L +Q++ D++VT+ Q+ A M+L+W  A  + DPG   
Sbjct: 249 RGLSKNLSNGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQKSGDPG--- 305

Query: 350 AGILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKEL 409
                   M  LLA A L L  +KQ  L E ++  ++      LS V S FLS+N+T+ L
Sbjct: 306 --------MGKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDTQNL 357

Query: 410 NSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGS 469
           +SP+ F FSH              + V+  PRQ++LC FW+   +  GHWAT GC  +G+
Sbjct: 358 SSPVTFTFSH--------------RSVI--PRQKVLCVFWEHGQNGCGHWATTGCSTIGT 401

Query: 470 KNGSTTCQCSHLSSFAILMAHYDV--EDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQ 527
           ++ ST C+C+HLSSFA+LMAHYDV  ED  LT+IT +GL++SL CLLL  LTFLL + IQ
Sbjct: 402 RDTSTICRCTHLSSFAVLMAHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQ 461

Query: 528 GSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLE 587
            + T++HL L +CLF+   +FL  I+  G +V   C ++AG LHY +LA   WM LE L 
Sbjct: 462 NTSTSLHLQLSLCLFLAHLLFLVAIDQTGHKV--LCSIIAGTLHYLYLATLTWMLLEALY 519

Query: 588 LY-----FLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQG 642
           L+       VV          + +  +GYGVP + V +SAA     YG P  CWL  E+G
Sbjct: 520 LFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKG 579

Query: 643 FLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGC 702
           F+W FLGPV  I   N V+F+ T+W L  + S +N ++  L+  R L   A AQLF+LGC
Sbjct: 580 FIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGC 639

Query: 703 TWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWA 752
           TW  G+      + V+ Y+FTI+N LQG F++L++CLL+++VRE+Y KW+
Sbjct: 640 TWCLGILQVGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWS 689


>gi|23397687 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform d [Homo sapiens]
          Length = 681

 Score =  550 bits (1418), Expect = e-156
 Identities = 287/642 (44%), Positives = 403/642 (62%), Gaps = 35/642 (5%)

Query: 125 RLCKSYGTCVNTLGSYTCQCLPGF----KFIPEDPKVCTDVDECSS-GQHQCDSSTVCFN 179
           R C    +CVN      C+C PGF    + I    + C D++EC++  +  C   + C+N
Sbjct: 31  RWCPQDSSCVNATA---CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWN 87

Query: 180 TVGSYSCRCRPGWKPRHGIPN--NQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLG 237
           T GSY C C PG++P  G     N+ +  C+DMTFSTWTPPPGVHSQTLSRFFDKVQDLG
Sbjct: 88  TEGSYDCVCSPGYEPVSGAKTFKNESENTCQDMTFSTWTPPPGVHSQTLSRFFDKVQDLG 147

Query: 238 RDSKTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLP 297
           RD K   A  TIQ++++ +DEL+EAPGD+E L    +H +A+ LL  LED++R L+K+L 
Sbjct: 148 RDYKPGLANNTIQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLS 207

Query: 298 KGPFTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQN 357
            G   +  P+ TEL+L +Q++ D++VT+ Q+ A M+L+W  A  + DPGP+V G++SI  
Sbjct: 208 NGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQKSGDPGPSVVGLVSIPG 267

Query: 358 MTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAF 417
           M  LLA A L L  +KQ  L E ++  ++      LS V S FLS+N+T+ L+SP+ F F
Sbjct: 268 MGKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDTQNLSSPVTFTF 327

Query: 418 SHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQ 477
           SH              + V+  PRQ++LC FW+   +  GHWAT GC  +G+++ ST C+
Sbjct: 328 SH--------------RSVI--PRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICR 371

Query: 478 CSHLSSFAILMAHYDV--EDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHL 535
           C+HLSSFA+LMAHYDV  ED  LT+IT +GL++SL CLLL  LTFLL + IQ + T++HL
Sbjct: 372 CTHLSSFAVLMAHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHL 431

Query: 536 HLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELY-----F 590
            L +CLF+   +FL  I+  G +V   C ++AG LHY +LA   WM LE L L+      
Sbjct: 432 QLSLCLFLAHLLFLVAIDQTGHKV--LCSIIAGTLHYLYLATLTWMLLEALYLFLTARNL 489

Query: 591 LVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGP 650
            VV          + +  +GYGVP + V +SAA     YG P  CWL  E+GF+W FLGP
Sbjct: 490 TVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGP 549

Query: 651 VTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFI 710
           V  I   N V+F+ T+W L  + S +N ++  L+  R L   A AQLF+LGCTW  G+  
Sbjct: 550 VCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQ 609

Query: 711 FDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWA 752
               + V+ Y+FTI+N LQG F++L++CLL+++VRE+Y KW+
Sbjct: 610 VGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWS 651



 Score =  247 bits (630), Expect = 3e-65
 Identities = 113/120 (94%), Positives = 115/120 (95%), Gaps = 3/120 (2%)

Query: 1   MGGRVFL---AFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITT 57
           MGGRVFL   AFCVWLTLPGAETQDSRGCARWCPQ+SSCVNATACRCNPGFSSFSEIITT
Sbjct: 1   MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITT 60

Query: 58  PTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 117
           P ETCDDINECAT SKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQD+
Sbjct: 61  PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDM 120


>gi|40807489 egf-like module containing, mucin-like, hormone
           receptor-like sequence 1 [Homo sapiens]
          Length = 886

 Score =  412 bits (1059), Expect = e-115
 Identities = 250/784 (31%), Positives = 401/784 (51%), Gaps = 98/784 (12%)

Query: 30  CPQNSSCVNAT---ACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTE 86
           CP++S CVN+    +C C  GF S +        TC+D++ECA P   +C + + C NT 
Sbjct: 142 CPEHSDCVNSMGSYSCSCQVGFISRNS-------TCEDVDECADPR--ACPEHATCNNTV 192

Query: 87  GSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLP 146
           G+Y C C+PG+E  SG  +F+   + +C+D+DEC +   +C    TC NT GSY C C P
Sbjct: 193 GNYSCFCNPGFESSSGHLSFQG-LKASCEDIDECTE---MCPINSTCTNTPGSYFCTCHP 248

Query: 147 GFKFIPEDPKV--------CTDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGI 198
           GF   P + ++        C D+DEC      C  +++C N +GSYSC C  G+ P    
Sbjct: 249 GFA--PSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEG 306

Query: 199 PNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVT----IQNVIK 254
                +  C+ + F           + +     ++Q     +    A V+    I N+  
Sbjct: 307 SQKDGNFSCQRVLFKC--------KEDVIPDNKQIQQCQEGTAVKPAYVSFCAQINNIFS 358

Query: 255 LVDELMEAPGDVEALAP------PVRHLIAT------QLLSNLEDIMRILAKSLPKGPF- 301
           ++D++ E    V +L        PV   I+T      +  S+L  +     +S+    F 
Sbjct: 359 VLDKVCENKTTVVSLKNTTESFVPVLKQISTWTKFTKEETSSLATVFLESVESMTLASFW 418

Query: 302 ---TYISPS------NTELTLMIQERGDKNVTMG--QSSARMKLNWAVAAGAEDPGPAVA 350
                I+P+      + E  ++ +E  ++NVT+       +MK+  +    +E       
Sbjct: 419 KPSANITPAVRTEYLDIESKVINKECSEENVTLDLVAKGDKMKIGCSTIEESESTETTGV 478

Query: 351 GILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELN 410
             +S   M ++L       H       E         ++L+  S V    ++       +
Sbjct: 479 AFVSFVGMESVLNERFFKDHQAPLTTSE---------IKLKMNSRVVGGIMTGEKKDGFS 529

Query: 411 SPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSK 470
            PI++   +++         P  K   P      +C  W +D  +GG W + GC +L + 
Sbjct: 530 DPIIYTLENIQ---------PKQKFERP------ICVSWSTDV-KGGRWTSFGCVILEAS 573

Query: 471 NGSTTCQCSHLSSFAILMAHYDVE-DWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGS 529
              T C C+ +++ A++MA  ++  D+ L +I+ VG+ +SL CL+L I TFLL R I+  
Sbjct: 574 ETYTICSCNQMANLAVIMASGELTMDFSLYIISHVGIIISLVCLVLAIATFLLCRSIRNH 633

Query: 530 RTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELY 589
            T +HLHLC+CL +  T+FLAGI     ++G  C ++AG LHY FLA F WM +E + L+
Sbjct: 634 NTYLHLHLCVCLLLAKTLFLAGIHKTDNKMG--CAIIAGFLHYLFLACFFWMLVEAVILF 691

Query: 590 FLV-----VRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFL 644
            +V     V  F  + +    +C  GYG+P+L+V +SA++  +GYG    CWL+ E GF+
Sbjct: 692 LMVRNLKVVNYFSSRNIKMLHICAFGYGLPMLVVVISASVQPQGYGMHNRCWLNTETGFI 751

Query: 645 WSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTW 704
           WSFLGPV  +I+ N+++   T+W L Q+ S +N ++  LK  R LT  A AQLF+LGC+W
Sbjct: 752 WSFLGPVCTVIVINSLLLTWTLWILRQRLSSVNAEVSTLKDTRLLTFKAFAQLFILGCSW 811

Query: 705 VFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWACLVAGGSKYSEF 764
           V G+F     + V+ Y+FTI+N LQGAF++L+HCLLN +VREEY++W   + G +K S  
Sbjct: 812 VLGIFQIGPVAGVMAYLFTIINSLQGAFIFLIHCLLNGQVREEYKRW---ITGKTKPSSQ 868

Query: 765 TSTT 768
           + T+
Sbjct: 869 SQTS 872



 Score = 95.5 bits (236), Expect = 2e-19
 Identities = 50/143 (34%), Positives = 73/143 (51%), Gaps = 18/143 (12%)

Query: 76  CGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVN 135
           C  ++ C NT  SY C C  G+   +G   FK+     C+D+DEC Q+P+ C    +C N
Sbjct: 41  CPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVR-CKDIDECSQSPQPCGPNSSCKN 99

Query: 136 TLGSYTCQCLPGFK------FIPEDPK--VCTDVDECSSGQHQCDSSTVCFNTVGSYSCR 187
             G Y C CL GF       ++P  P    CTD++EC +    C   + C N++GSYSC 
Sbjct: 100 LSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSS-VCPEHSDCVNSMGSYSCS 158

Query: 188 CRPGWKPRHGIPNNQKDTVCEDM 210
           C+ G+  R        ++ CED+
Sbjct: 159 CQVGFISR--------NSTCEDV 173



 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 38/112 (33%), Positives = 49/112 (43%), Gaps = 16/112 (14%)

Query: 108 NESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIP-----EDPKV-CTDV 161
           N   N C+D         LC +Y TC NT+ SY C C  GF         +DP V C D+
Sbjct: 29  NTKGNNCRD-------STLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDI 81

Query: 162 DECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHG---IPNNQKDTVCEDM 210
           DECS     C  ++ C N  G Y C C  G+    G   +P    +  C D+
Sbjct: 82  DECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDI 133


>gi|133930786 egf-like module-containing mucin-like receptor 3 [Homo
           sapiens]
          Length = 652

 Score =  309 bits (792), Expect = 6e-84
 Identities = 207/671 (30%), Positives = 324/671 (48%), Gaps = 93/671 (13%)

Query: 127 CKSYGTCVNTLGSYTCQCLPGF------KFIPEDPKVCTDVDECSSGQH-QCDSSTVCFN 179
           C    +CVN      C C  G+      K      + C D++EC+      C  + VC+N
Sbjct: 31  CPPNASCVNNTH---CTCNHGYTSGSGQKLFTFPLETCNDINECTPPYSVYCGFNAVCYN 87

Query: 180 TVGSYSCRCRPGWKPRHGIP--NNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDL- 236
             GS+ C+C PG++   G    +N  +  C+D T S  T       + L +  DK + L 
Sbjct: 88  VEGSFYCQCVPGYRLHSGNEQFSNSNENTCQDTTSSKTTEG----RKELQKIVDKFESLL 143

Query: 237 ---------GRDSKTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLED 287
                    GR   +S+A   +++V   V E         AL  P + ++  Q      D
Sbjct: 144 TNQTLWRTEGRQEISSTATTILRDVESKVLET--------ALKDPEQKVLKIQ-----ND 190

Query: 288 IMRILAKSLPKGPFTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGP 347
            + I  +++                   +ER   N+ +  +S  ++ +  +    +  GP
Sbjct: 191 SVAIETQAITDN--------------CSEERKTFNLNVQMNSMDIRCSDIIQGDTQ--GP 234

Query: 348 AVAGILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTK 407
           +    +S  ++  ++         KK    +++Y +S           V S  +      
Sbjct: 235 SAIAFISYSSLGNIINATFFEEMDKK----DQVYLNS----------QVVSAAIGPKRNV 280

Query: 408 ELNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVL 467
            L+  +   F H++ +       P  K V         C +WKS + +G  W+ +GC ++
Sbjct: 281 SLSKSVTLTFQHVKMT-------PSTKKVF--------CVYWKS-TGQGSQWSRDGCFLI 324

Query: 468 GSKNGSTTCQCSHLSSFAILMA-HYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPI 526
                 T C CSHLSSFA+LMA     ED  LT+IT VGL++SL CLLL  LTFLL + I
Sbjct: 325 HVNKSHTMCNCSHLSSFAVLMALTSQEEDPVLTVITYVGLSVSLLCLLLAALTFLLCKAI 384

Query: 527 QGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGL 586
           + + T++HL L +CLF+   +FL GI+    +V   C ++AG LHY +LAAF WM LEG+
Sbjct: 385 RNTSTSLHLQLSLCLFLAHLLFLVGIDRTEPKV--LCSIIAGALHYLYLAAFTWMLLEGV 442

Query: 587 ELYF----LVVRVFQGQGLSTRWLCL-IGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQ 641
            L+     L V  +       +W+   +GYGVP + V +SAA +   YG    CWL  +Q
Sbjct: 443 HLFLTARNLTVVNYSSINRLMKWIMFPVGYGVPAVTVAISAASWPHLYGTADRCWLHLDQ 502

Query: 642 GFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLG 701
           GF+WSFLGPV  I   N V+F+   W L +K S +N ++  ++  R L   A AQLF+LG
Sbjct: 503 GFMWSFLGPVCAIFSANLVLFILVFWILKRKLSSLNSEVSTIQNTRMLAFKATAQLFILG 562

Query: 702 CTWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWACLVAGGSKY 761
           CTW  GL      + V+ Y+FTI+N LQG F++L++CLL+++V+++Y+KW   +      
Sbjct: 563 CTWCLGLLQVGPAAQVMAYLFTIINSLQGFFIFLVYCLLSQQVQKQYQKWFREIVKSKSE 622

Query: 762 SEFTSTTSGTG 772
           SE  + +S  G
Sbjct: 623 SETYTLSSKMG 633



 Score =  114 bits (285), Expect = 3e-25
 Identities = 55/109 (50%), Positives = 69/109 (63%), Gaps = 2/109 (1%)

Query: 10  CVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFS--EIITTPTETCDDINE 67
           C  L+L GA TQ ++     CP N+SCVN T C CN G++S S  ++ T P ETC+DINE
Sbjct: 11  CFLLSLFGAVTQKTKTSCAKCPPNASCVNNTHCTCNHGYTSGSGQKLFTFPLETCNDINE 70

Query: 68  CATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQD 116
           C  P  V CG  + C+N EGS+ C C PGY   SG + F N +ENTCQD
Sbjct: 71  CTPPYSVYCGFNAVCYNVEGSFYCQCVPGYRLHSGNEQFSNSNENTCQD 119


>gi|6912464 latrophilin 2 precursor [Homo sapiens]
          Length = 1403

 Score =  294 bits (753), Expect = 2e-79
 Identities = 153/368 (41%), Positives = 218/368 (59%), Gaps = 30/368 (8%)

Query: 395  AVNSIFLSHNNTKE-----LNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFW 449
            AVNS  +S +  KE     L  P+LF   H++                P       C+FW
Sbjct: 735  AVNSHVISVSINKESSRVYLTDPVLFTLPHID----------------PDNYFNANCSFW 778

Query: 450  K-SDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYD------VEDWKLTLIT 502
              S+    G+W+T+GC+++ +    TTC CSHL++FAILMAH +      V +  LT+IT
Sbjct: 779  NYSERTMMGYWSTQGCKLVDTNKTRTTCACSHLTNFAILMAHREIAYKDGVHELLLTVIT 838

Query: 503  RVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLR 562
             VG+ +SL CL +CI TF   R +Q  R TIH +LCI LF+   IFL GI+    +  + 
Sbjct: 839  WVGIVISLVCLAICIFTFCFFRGLQSDRNTIHKNLCINLFIAEFIFLIGIDKT--KYAIA 896

Query: 563  CRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSA 622
            C + AGLLH+ FLAAF WM LEG++LY ++V VF+ +    ++  + GY  P  +VGVSA
Sbjct: 897  CPIFAGLLHFFFLAAFAWMCLEGVQLYLMLVEVFESEYSRKKYYYVAGYLFPATVVGVSA 956

Query: 623  AIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKK 682
            AI  K YG  + CWL  +  F+WSF+GPVTFIIL N +  V T+ K+ +  + + PD  +
Sbjct: 957  AIDYKSYGTEKACWLHVDNYFIWSFIGPVTFIILLNIIFLVITLCKMVKHSNTLKPDSSR 1016

Query: 683  LKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNK 742
            L+  ++  + A A L LLG TW FGL   ++ ++V+ Y+FTI N  QG F+++ HC L K
Sbjct: 1017 LENIKSWVLGAFALLCLLGLTWSFGLLFINEETIVMAYLFTIFNAFQGVFIFIFHCALQK 1076

Query: 743  KVREEYRK 750
            KVR+EY K
Sbjct: 1077 KVRKEYGK 1084


>gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]
          Length = 1474

 Score =  291 bits (746), Expect = 1e-78
 Identities = 159/399 (39%), Positives = 232/399 (58%), Gaps = 35/399 (8%)

Query: 396  VNSIFLSHNNTKE-----LNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWK 450
            VNS  ++ +  KE     L  P++F  +HLE  +                     C+FW 
Sbjct: 763  VNSQVIAASINKESSRVFLMDPVIFTVAHLEDKNHFNAN----------------CSFWN 806

Query: 451  -SDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYDVEDWK-----LTLITRV 504
             S+    G+W+T+GC+++ S    TTC CSHL++FA+LMAH ++   +     L++IT V
Sbjct: 807  YSERSMLGYWSTQGCRLVESNKTHTTCACSHLTNFAVLMAHREIYQGRINELLLSVITWV 866

Query: 505  GLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCR 564
            G+ +SL CL +CI TF  +R +Q  R TIH +LCI LF+   +FL GI+    Q  + C 
Sbjct: 867  GIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINLFLAELLFLVGIDKT--QYEIACP 924

Query: 565  LVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAI 624
            + AGLLHY FLAAF W+ LEG+ LY L+V VF+ +   T++  L GY  P L+VG++AAI
Sbjct: 925  IFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFESEYSRTKYYYLGGYCFPALVVGIAAAI 984

Query: 625  YSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLK 684
              + YG  + CWL  +  F+WSF+GPV+F+I+ N V  + T+ K+ +  S + PD  +L 
Sbjct: 985  DYRSYGTEKACWLRVDNYFIWSFIGPVSFVIVVNLVFLMVTLHKMIRSSSVLKPDSSRLD 1044

Query: 685  KARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKV 744
              ++  + AIA LFLLG TW FGL   +  S+V+ Y+FT  N  QG F+++ HC L KKV
Sbjct: 1045 NIKSWALGAIALLFLLGLTWAFGLLFINKESVVMAYLFTTFNAFQGVFIFVFHCALQKKV 1104

Query: 745  REEYRKWACLVAGGSKYSEFTSTTSGT-GHNQTRALRAS 782
             +EY K  CL      Y    S   GT G  +T A+R++
Sbjct: 1105 HKEYSK--CL---RHSYCCIRSPPGGTHGSLKTSAMRSN 1138


>gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]
          Length = 1469

 Score =  291 bits (746), Expect = 1e-78
 Identities = 159/399 (39%), Positives = 232/399 (58%), Gaps = 35/399 (8%)

Query: 396  VNSIFLSHNNTKE-----LNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWK 450
            VNS  ++ +  KE     L  P++F  +HLE  +                     C+FW 
Sbjct: 758  VNSQVIAASINKESSRVFLMDPVIFTVAHLEDKNHFNAN----------------CSFWN 801

Query: 451  -SDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYDVEDWK-----LTLITRV 504
             S+    G+W+T+GC+++ S    TTC CSHL++FA+LMAH ++   +     L++IT V
Sbjct: 802  YSERSMLGYWSTQGCRLVESNKTHTTCACSHLTNFAVLMAHREIYQGRINELLLSVITWV 861

Query: 505  GLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCR 564
            G+ +SL CL +CI TF  +R +Q  R TIH +LCI LF+   +FL GI+    Q  + C 
Sbjct: 862  GIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINLFLAELLFLVGIDKT--QYEIACP 919

Query: 565  LVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAI 624
            + AGLLHY FLAAF W+ LEG+ LY L+V VF+ +   T++  L GY  P L+VG++AAI
Sbjct: 920  IFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFESEYSRTKYYYLGGYCFPALVVGIAAAI 979

Query: 625  YSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLK 684
              + YG  + CWL  +  F+WSF+GPV+F+I+ N V  + T+ K+ +  S + PD  +L 
Sbjct: 980  DYRSYGTEKACWLRVDNYFIWSFIGPVSFVIVVNLVFLMVTLHKMIRSSSVLKPDSSRLD 1039

Query: 685  KARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKV 744
              ++  + AIA LFLLG TW FGL   +  S+V+ Y+FT  N  QG F+++ HC L KKV
Sbjct: 1040 NIKSWALGAIALLFLLGLTWAFGLLFINKESVVMAYLFTTFNAFQGVFIFVFHCALQKKV 1099

Query: 745  REEYRKWACLVAGGSKYSEFTSTTSGT-GHNQTRALRAS 782
             +EY K  CL      Y    S   GT G  +T A+R++
Sbjct: 1100 HKEYSK--CL---RHSYCCIRSPPGGTHGSLKTSAMRSN 1133


>gi|148806925 EGF, latrophilin and seven transmembrane domain
           containing 1 [Homo sapiens]
          Length = 690

 Score =  291 bits (744), Expect = 2e-78
 Identities = 209/704 (29%), Positives = 330/704 (46%), Gaps = 78/704 (11%)

Query: 72  SKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYG 131
           +K  C   + C    G   C C+ G         F       C+D +EC    + C    
Sbjct: 23  TKTPCLPNAKCEIRNGIEACYCNMG---------FSGNGVTICEDDNECGNLTQSCGENA 73

Query: 132 TCVNTLGSYTCQCLPGF-------KFIPEDPKVCTDVDECSSGQHQCDSSTVCF-NTVGS 183
            C NT GSY C C+PGF       +FI  D  VC +     +    C    VC    +  
Sbjct: 74  NCTNTEGSYYCMCVPGFRSSSNQDRFITNDGTVCIE-----NVNANCHLDNVCIAANINK 128

Query: 184 YSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTS 243
              + R   +P   +    +++V       T   P  + +  +    +    LG  + T 
Sbjct: 129 TLTKIRSIKEPVALLQEVYRNSV-------TDLSPTDIITY-IEILAESSSLLGYKNNTI 180

Query: 244 SAEVTIQN-----VIKLVDELMEAPGDV--EALAPPVRHLIATQLLSNLEDIMRILAKSL 296
           SA+ T+ N      +K V+  ++    V  + L+   R    T+L+  +E     +++S 
Sbjct: 181 SAKDTLSNSTLTEFVKTVNNFVQRDTFVVWDKLSVNHRRTHLTKLMHTVEQATLRISQSF 240

Query: 297 PKGPFTYISPSNTELTLMIQERGDKNVT-----MGQSSARMKLNWAVAAGAEDPGPAVAG 351
            K   T    ++T++ L +      N+      M      + +     A  +  G     
Sbjct: 241 QK--TTEFDTNSTDIALKVFFFDSYNMKHIHPHMNMDGDYINIFPKRKAAYDSNGNVAVA 298

Query: 352 ILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHN--NTKEL 409
            +  +++  LL+++   L   +  +  E  E        R +S+V S+ +S N     EL
Sbjct: 299 FVYYKSIGPLLSSSDNFLLKPQNYDNSEEEE--------RVISSVISVSMSSNPPTLYEL 350

Query: 410 NSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSD-RGGHWATEGCQVLG 468
              I F  SH + +D                R   LCAFW    D   G W++EGC++  
Sbjct: 351 EK-ITFTLSHRKVTD----------------RYRSLCAFWNYSPDTMNGSWSSEGCELTY 393

Query: 469 SKNGSTTCQCSHLSSFAILMA---HYDVEDWK-LTLITRVGLALSLFCLLLCILTFLLVR 524
           S    T+C+C+HL+ FAILM+      ++D+  LT IT++G+ +SL CL +CI TF    
Sbjct: 394 SNETHTSCRCNHLTHFAILMSSGPSIGIKDYNILTRITQLGIIISLICLAICIFTFWFFS 453

Query: 525 PIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLE 584
            IQ +RTTIH +LC  LF+   +FL GI     +  L C ++AGLLHY FLAAF WM +E
Sbjct: 454 EIQSTRTTIHKNLCCSLFLAELVFLVGINTNTNK--LFCSIIAGLLHYFFLAAFAWMCIE 511

Query: 585 GLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFL 644
           G+ LY +VV V   +G   +   + GY  P ++VG SAA+  + YG  + CWL  E  F+
Sbjct: 512 GIHLYLIVVGVIYNKGFLHKNFYIFGYLSPAVVVGFSAALGYRYYGTTKVCWLSTENNFI 571

Query: 645 WSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTW 704
           WSF+GP   IIL N + F   ++K+ +  + + P++   +  R+    A+A LFLLG TW
Sbjct: 572 WSFIGPACLIILVNLLAFGVIIYKVFRHTAGLKPEVSCFENIRSCARGALALLFLLGTTW 631

Query: 705 VFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEY 748
           +FG+      S+V  Y+FT+ N  QG F++L  C+L++K++EEY
Sbjct: 632 IFGVLHVVHASVVTAYLFTVSNAFQGMFIFLFLCVLSRKIQEEY 675



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 33/88 (37%), Positives = 42/88 (47%), Gaps = 10/88 (11%)

Query: 30  CPQNSSCV---NATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTE 86
           C  N+ C       AC CN GFS     I      C+D NEC   ++ SCG+ ++C NTE
Sbjct: 27  CLPNAKCEIRNGIEACYCNMGFSGNGVTI------CEDDNECGNLTQ-SCGENANCTNTE 79

Query: 87  GSYDCVCSPGYEPVSGAKTFKNESENTC 114
           GSY C+C PG+   S    F       C
Sbjct: 80  GSYYCMCVPGFRSSSNQDRFITNDGTVC 107


>gi|163792198 latrophilin 3 precursor [Homo sapiens]
          Length = 1469

 Score =  280 bits (717), Expect = 3e-75
 Identities = 155/394 (39%), Positives = 227/394 (57%), Gaps = 25/394 (6%)

Query: 401  LSHNNTKELNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELL----CAFWK-SDSDR 455
            LS N++  +NSP++ A  + E S+     DP    V    + E      C+FW  S    
Sbjct: 769  LSTNHSVIVNSPVITAAINKEFSNKVYLADPVVFTVKHIKQSEENFNPNCSFWSYSKRTM 828

Query: 456  GGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYDVE------DWKLTLITRVGLALS 509
             G+W+T+GC++L +    TTC C+HL++FA+LMAH +V+      D  L +IT VG+ LS
Sbjct: 829  TGYWSTQGCRLLTTNKTHTTCSCNHLTNFAVLMAHVEVKHSDAVHDLLLDVITWVGILLS 888

Query: 510  LFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGL 569
            L CLL+CI TF   R +Q  R TIH +LCI LFV   +FL GI      +   C + A L
Sbjct: 889  LVCLLICIFTFCFFRGLQSDRNTIHKNLCISLFVAELLFLIGINRTDQPIA--CAVFAAL 946

Query: 570  LHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGY 629
            LH+ FLAAF WM LEG++LY ++V VF+ +    ++  L+GYG+P LIV VSAA+  + Y
Sbjct: 947  LHFFFLAAFTWMFLEGVQLYIMLVEVFESEHSRRKYFYLVGYGMPALIVAVSAAVDYRSY 1006

Query: 630  GRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKK---- 685
            G  + CWL  +  F+WSF+GP T II+ N +     ++K+    + + P+   L      
Sbjct: 1007 GTDKVCWLRLDTYFIWSFIGPATLIIMLNVIFLGIALYKMFHHTAILKPESGCLDNINYE 1066

Query: 686  -----ARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLL 740
                  ++  I AIA L LLG TW FGL   ++ ++++ Y+FTI N LQG F+++ HC+L
Sbjct: 1067 DNRPFIKSWVIGAIALLCLLGLTWAFGLMYINESTVIMAYLFTIFNSLQGMFIFIFHCVL 1126

Query: 741  NKKVREEYRKWA---CLVAGGSKYSEFTSTTSGT 771
             KKVR+EY K     C     ++ S  +  TSG+
Sbjct: 1127 QKKVRKEYGKCLRTHCCSGKSTESSIGSGKTSGS 1160


>gi|45433552 G protein-coupled receptor 133 [Homo sapiens]
          Length = 874

 Score =  191 bits (486), Expect = 2e-48
 Identities = 113/316 (35%), Positives = 171/316 (54%), Gaps = 19/316 (6%)

Query: 446 CAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYDVE-----DWKLTL 500
           CAF    S  G  W+  GC +       + C+C+HL++FAILM    +E        L+ 
Sbjct: 510 CAFLDFSSGEGV-WSNHGCALTRGNLTYSVCRCTHLTNFAILMQVVPLELARGHQVALSS 568

Query: 501 ITRVGLALSLFCLLLCILTFLL---VRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGG 557
           I+ VG +LS+ CL+  ++TF +   V  I+  R  IH +L   + V   + L     E G
Sbjct: 569 ISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVLLLISFRLEPG 628

Query: 558 QVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLI 617
                C+++A LLHY FL+AF WM +EGL LY +V++VF  +    R+   +G+G PLLI
Sbjct: 629 TTP--CQVMAVLLHYFFLSAFAWMLVEGLHLYSMVIKVFGSEDSKHRYYYGMGWGFPLLI 686

Query: 618 VGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEIN 677
             +S +     YG    CWL    G +W+F+ P  F+I+ N  I +     +T+  S+I+
Sbjct: 687 CIISLSFAMDSYGTSNNCWLSLASGAIWAFVAPALFVIVVNIGILIA----VTRVISQIS 742

Query: 678 PDMKKL---KKARALTITAIAQLF-LLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFL 733
            D  K+     A  LT  A+A L  +LG +WVFG+   +  ++V  Y+F  LN LQG F+
Sbjct: 743 ADNYKIHGDPSAFKLTAKAVAVLLPILGTSWVFGVLAVNGCAVVFQYMFATLNSLQGLFI 802

Query: 734 YLLHCLLNKKVREEYR 749
           +L HCLLN +VR  ++
Sbjct: 803 FLFHCLLNSEVRAAFK 818


>gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo
            sapiens]
          Length = 3014

 Score =  189 bits (481), Expect = 7e-48
 Identities = 122/408 (29%), Positives = 196/408 (48%), Gaps = 39/408 (9%)

Query: 377  LEEIYESSIRGVQLRRLSAVNSIFLSHNNTKE-------LNSPILFAFSHLESSDGEAGR 429
            L E Y+   R ++L     +N+  +S     E       L  P+L  F+ LE  +     
Sbjct: 2351 LPERYDPDRRSLRLPHRPIINTPMVSTLVYSEGAPLPRPLERPVLVEFALLEVEE----- 2405

Query: 430  DPPAKDVMPGPRQELLCAFWKSDSDRGGH--WATEGCQVLGSKNGSTTCQCSHLSSFAIL 487
                       R + +C FW      GG   W+  GC++L        CQCSH +SFA+L
Sbjct: 2406 -----------RTKPVCVFWNHSLAVGGTGGWSARGCELLSRNRTHVACQCSHTASFAVL 2454

Query: 488  M---AHYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVG 544
            M      + E   L ++T   ++LSL  LL+  +   LVR ++ +  +IH HL + LF+ 
Sbjct: 2455 MDISRRENGEVLPLKIVTYAAVSLSLAALLVAFVLLSLVRMLRSNLHSIHKHLAVALFLS 2514

Query: 545  STIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTR 604
              +F+ GI          C +VA LLHY +++ F W  +E L +Y ++  V        R
Sbjct: 2515 QLVFVIGINQTENP--FLCTVVAILLHYIYMSTFAWTLVESLHVYRMLTEVRNIDTGPMR 2572

Query: 605  WLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVT 664
            +  ++G+G+P ++ G++  +  +GYG P +CWL  +   +WSF GP+  +I+ N V  V 
Sbjct: 2573 FYYVVGWGIPAIVTGLAVGLDPQGYGNPDFCWLSLQDTLIWSFAGPIGAVIIINTVTSVL 2632

Query: 665  TVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTI 724
            +     Q+           K   +L  TA   L L+  TW+ GL   +  +L   Y+F I
Sbjct: 2633 SAKVSCQR----KHHYYGKKGIVSLLRTAFLLLLLISATWLLGLLAVNRDALSFHYLFAI 2688

Query: 725  LNCLQGAFLYLLHCLLNKKVREEYRKWACLVAGGSK-YSEFTSTTSGT 771
             + LQG F+ L HC+LN++VR+  +     V GG K + E ++TT  T
Sbjct: 2689 FSGLQGPFVLLFHCVLNQEVRKHLKG----VLGGRKLHLEDSATTRAT 2732



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 34/113 (30%), Positives = 49/113 (43%), Gaps = 25/113 (22%)

Query: 37   VNATACRCNPGFSSFSEIITTPTETCD-DINECATPSKVSCGKFSDCWNTEGSYDCVCSP 95
            +N   CRC PGF+          + C+ +I+ C +     CG    C + EG Y C C  
Sbjct: 1344 INGLRCRCPPGFTG---------DYCETEIDLCYSD---PCGANGRCRSREGGYTCEC-- 1389

Query: 96   GYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTL-GSYTCQCLPG 147
             +E  +G     +     C +         +CK+ GTCVN L G + C C PG
Sbjct: 1390 -FEDFTGEHCEVDARSGRCAN--------GVCKNGGTCVNLLIGGFHCVCPPG 1433



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 20/103 (19%)

Query: 91   CVCSPGYEPVSGAKTFKNESENTCQ-DVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFK 149
            C C PG+            + + C+ ++D C  +P  C + G C +  G YTC+C     
Sbjct: 1349 CRCPPGF------------TGDYCETEIDLCYSDP--CGANGRCRSREGGYTCECFE--D 1392

Query: 150  FIPEDPKVCTDVDECSSGQHQCDSSTVCFN-TVGSYSCRCRPG 191
            F  E  +V      C++G   C +   C N  +G + C C PG
Sbjct: 1393 FTGEHCEVDARSGRCANG--VCKNGGTCVNLLIGGFHCVCPPG 1433



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 33/126 (26%), Positives = 47/126 (37%), Gaps = 28/126 (22%)

Query: 24   RGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCW 83
            RGC +      +  N      N      + +     + CD  + C +     C   S C 
Sbjct: 1838 RGCMQGVRMGGTPTNVATLNMN------NALKVRVKDGCDVDDPCTSSP---CPPNSRCH 1888

Query: 84   NTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGS---Y 140
            +    Y CVC  GY  ++            C  VD C  NP  C++ G CV + GS   Y
Sbjct: 1889 DAWEDYSCVCDKGYLGIN------------C--VDACHLNP--CENMGACVRSPGSPQGY 1932

Query: 141  TCQCLP 146
             C+C P
Sbjct: 1933 VCECGP 1938


>gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo
            sapiens]
          Length = 2923

 Score =  166 bits (420), Expect = 8e-41
 Identities = 112/404 (27%), Positives = 189/404 (46%), Gaps = 37/404 (9%)

Query: 363  ANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLS---HNNT----KELNSPILF 415
            A AS+ ++      L   Y+   R +++ +   +N+  +S   H++     + L+ P+  
Sbjct: 2245 AVASVIIYRTLAGLLPHNYDPDKRSLRVPKRPIINTPVVSISVHDDEELLPRALDKPVTV 2304

Query: 416  AFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSD---SDRGGHWATEGCQVLGSKNG 472
             F  LE+ +                R + +C FW      S  GG W+  GC+V+     
Sbjct: 2305 QFRLLETEE----------------RTKPICVFWNHSILVSGTGG-WSARGCEVVFRNES 2347

Query: 473  STTCQCSHLSSFAILM---AHYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGS 529
              +CQC+H++SFA+LM      + E   L  +T V L ++L  LLL      L+R ++ +
Sbjct: 2348 HVSCQCNHMTSFAVLMDVSRRENGEILPLKTLTYVALGVTLAALLLTFFFLTLLRILRSN 2407

Query: 530  RTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELY 589
            +  I  +L   L +   +FL GI      +   C ++A LLH+ +L  F W  LE L LY
Sbjct: 2408 QHGIRRNLTAALGLAQLVFLLGINQ--ADLPFACTVIAILLHFLYLCTFSWALLEALHLY 2465

Query: 590  FLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLG 649
              +  V        R+  ++G+GVP  I G++  +  +GYG P +CWL      +WSF G
Sbjct: 2466 RALTEVRDVNTGPMRFYYMLGWGVPAFITGLAVGLDPEGYGNPDFCWLSIYDTLIWSFAG 2525

Query: 650  PVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLF 709
            PV F +  +  +++          +      +K      L   + A L LL  TW+  L 
Sbjct: 2526 PVAFAVSMSVFLYILAA---RASCAAQRQGFEKKGPVSGLQ-PSFAVLLLLSATWLLALL 2581

Query: 710  IFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWAC 753
              +  +L+  Y+F   NC+QG F++L + +L+K+VR+   K AC
Sbjct: 2582 SVNSDTLLFHYLFATCNCIQGPFIFLSYVVLSKEVRKAL-KLAC 2624



 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 34/112 (30%), Positives = 44/112 (39%), Gaps = 23/112 (20%)

Query: 37   VNATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPG 96
            V    CRC PGF+   +   T  + C             CG    C + EG Y C+C  G
Sbjct: 1269 VGGLRCRCPPGFTG--DYCETEVDLC---------YSRPCGPHGRCRSREGGYTCLCRDG 1317

Query: 97   YEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTL-GSYTCQCLPG 147
            Y   +G     +     C         P +CK+ GTCVN L G + C C  G
Sbjct: 1318 Y---TGEHCEVSARSGRC--------TPGVCKNGGTCVNLLVGGFKCDCPSG 1358



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 31/107 (28%), Positives = 43/107 (40%), Gaps = 20/107 (18%)

Query: 87   GSYDCVCSPGYEPVSGAKTFKNESENTCQ-DVDECQQNPRLCKSYGTCVNTLGSYTCQCL 145
            G   C C PG+            + + C+ +VD C   P  C  +G C +  G YTC C 
Sbjct: 1270 GGLRCRCPPGF------------TGDYCETEVDLCYSRP--CGPHGRCRSREGGYTCLCR 1315

Query: 146  PGFKFIPEDPKVCTDVDECSSGQHQCDSSTVCFN-TVGSYSCRCRPG 191
             G  +  E  +V      C+ G   C +   C N  VG + C C  G
Sbjct: 1316 DG--YTGEHCEVSARSGRCTPG--VCKNGGTCVNLLVGGFKCDCPSG 1358



 Score = 36.2 bits (82), Expect = 0.12
 Identities = 21/64 (32%), Positives = 29/64 (45%), Gaps = 8/64 (12%)

Query: 134  VNTLGSYTCQCLPGFKFIPEDPKVC-TDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 192
            ++ +G   C+C PGF         C T+VD C S    C     C +  G Y+C CR G+
Sbjct: 1266 IHPVGGLRCRCPPGFT-----GDYCETEVDLCYS--RPCGPHGRCRSREGGYTCLCRDGY 1318

Query: 193  KPRH 196
               H
Sbjct: 1319 TGEH 1322



 Score = 34.7 bits (78), Expect = 0.35
 Identities = 23/76 (30%), Positives = 29/76 (38%), Gaps = 19/76 (25%)

Query: 76   CGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVN 135
            C   S C N   SY C C PGY              + C +V  C  NP  C+    C  
Sbjct: 1802 CPANSYCSNDWDSYSCSCDPGY------------YGDNCTNV--CDLNP--CEHQSVCTR 1845

Query: 136  TLGS---YTCQCLPGF 148
               +   YTC+C P +
Sbjct: 1846 KPSAPHGYTCECPPNY 1861



 Score = 32.3 bits (72), Expect = 1.7
 Identities = 14/35 (40%), Positives = 20/35 (57%), Gaps = 2/35 (5%)

Query: 158  CTDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 192
            C+  D C S  + C +++ C N   SYSC C PG+
Sbjct: 1791 CSLPDPCDS--NPCPANSYCSNDWDSYSCSCDPGY 1823



 Score = 31.2 bits (69), Expect = 3.9
 Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 9/60 (15%)

Query: 120  CQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVDECSSGQHQCDSSTVCFN 179
            C  N   C + GTCVN   +++C+C  GF       K C    E ++ QH   SS V ++
Sbjct: 1578 CDSNT--CHNGGTCVNQWDAFSCECPLGF-----GGKSC--AQEMANPQHFLGSSLVAWH 1628


>gi|223556012 G-protein coupled receptor 113 isoform 1 [Homo sapiens]
          Length = 1079

 Score =  159 bits (402), Expect = 9e-39
 Identities = 106/322 (32%), Positives = 160/322 (49%), Gaps = 14/322 (4%)

Query: 446  CAFWKSDSDRG-GHWATEGCQV-LGSKNGSTTCQCSHLSSFAILMAHYDV-EDWKLTLIT 502
            C FW     +G G W+ EGCQ  + S + +  C C HL++F++LM+ + V E+  L L+T
Sbjct: 715  CVFWDHSLFQGRGGWSKEGCQAQVASASPTAQCLCQHLTAFSVLMSPHTVPEEPALALLT 774

Query: 503  RVGLALSLFCLLLCILTFLLV------RPIQGSRTTIHLHLCICLFVGSTIFLAGIENEG 556
            +VGL  S+  LL+C+  + LV        I   R    L++  CL    T FL       
Sbjct: 775  QVGLGASILALLVCLGVYWLVWRVVVRNKISYFRHAALLNMVFCLLAADTCFLGAPFLSP 834

Query: 557  GQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQ--GQGLSTRWLCLIGYGVP 614
            G     C   A L H+ +LA F WM  + L L   ++ VF    +      + L+GY  P
Sbjct: 835  GPRSPLCLAAAFLCHFLYLATFFWMLAQALVLAHQLLFVFHQLAKHRVLPLMVLLGYLCP 894

Query: 615  LLIVGVSAAIY--SKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQK 672
            L + GV+  +Y     Y R   CWLD + G L++F+GPV  II  N ++    + KL + 
Sbjct: 895  LGLAGVTLGLYLPQGQYLREGECWLDGKGGALYTFVGPVLAIIGVNGLVLAMAMLKLLRP 954

Query: 673  FSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLF-IFDDRSLVLTYVFTILNCLQGA 731
                 P  +K +    +    +    + G TW  GL  + ++ S V  Y+FTILN LQG 
Sbjct: 955  SLSEGPPAEKRQALLGVIKALLILTPIFGLTWGLGLATLLEEVSTVPHYIFTILNTLQGV 1014

Query: 732  FLYLLHCLLNKKVREEYRKWAC 753
            F+ L  CL+++K++E  RK  C
Sbjct: 1015 FILLFGCLMDRKIQEALRKRFC 1036


>gi|223556014 G-protein coupled receptor 113 isoform 2 [Homo
           sapiens]
          Length = 997

 Score =  159 bits (402), Expect = 9e-39
 Identities = 106/322 (32%), Positives = 160/322 (49%), Gaps = 14/322 (4%)

Query: 446 CAFWKSDSDRG-GHWATEGCQV-LGSKNGSTTCQCSHLSSFAILMAHYDV-EDWKLTLIT 502
           C FW     +G G W+ EGCQ  + S + +  C C HL++F++LM+ + V E+  L L+T
Sbjct: 646 CVFWDHSLFQGRGGWSKEGCQAQVASASPTAQCLCQHLTAFSVLMSPHTVPEEPALALLT 705

Query: 503 RVGLALSLFCLLLCILTFLLV------RPIQGSRTTIHLHLCICLFVGSTIFLAGIENEG 556
           +VGL  S+  LL+C+  + LV        I   R    L++  CL    T FL       
Sbjct: 706 QVGLGASILALLVCLGVYWLVWRVVVRNKISYFRHAALLNMVFCLLAADTCFLGAPFLSP 765

Query: 557 GQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQ--GQGLSTRWLCLIGYGVP 614
           G     C   A L H+ +LA F WM  + L L   ++ VF    +      + L+GY  P
Sbjct: 766 GPRSPLCLAAAFLCHFLYLATFFWMLAQALVLAHQLLFVFHQLAKHRVLPLMVLLGYLCP 825

Query: 615 LLIVGVSAAIY--SKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQK 672
           L + GV+  +Y     Y R   CWLD + G L++F+GPV  II  N ++    + KL + 
Sbjct: 826 LGLAGVTLGLYLPQGQYLREGECWLDGKGGALYTFVGPVLAIIGVNGLVLAMAMLKLLRP 885

Query: 673 FSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLF-IFDDRSLVLTYVFTILNCLQGA 731
                P  +K +    +    +    + G TW  GL  + ++ S V  Y+FTILN LQG 
Sbjct: 886 SLSEGPPAEKRQALLGVIKALLILTPIFGLTWGLGLATLLEEVSTVPHYIFTILNTLQGV 945

Query: 732 FLYLLHCLLNKKVREEYRKWAC 753
           F+ L  CL+++K++E  RK  C
Sbjct: 946 FILLFGCLMDRKIQEALRKRFC 967


>gi|141802362 G-protein coupled receptor 113 isoform 3 [Homo
           sapiens]
          Length = 873

 Score =  159 bits (402), Expect = 9e-39
 Identities = 106/322 (32%), Positives = 160/322 (49%), Gaps = 14/322 (4%)

Query: 446 CAFWKSDSDRG-GHWATEGCQV-LGSKNGSTTCQCSHLSSFAILMAHYDV-EDWKLTLIT 502
           C FW     +G G W+ EGCQ  + S + +  C C HL++F++LM+ + V E+  L L+T
Sbjct: 516 CVFWDHSLFQGRGGWSKEGCQAQVASASPTAQCLCQHLTAFSVLMSPHTVPEEPALALLT 575

Query: 503 RVGLALSLFCLLLCILTFLLV------RPIQGSRTTIHLHLCICLFVGSTIFLAGIENEG 556
           +VGL  S+  LL+C+  + LV        I   R    L++  CL    T FL       
Sbjct: 576 QVGLGASILALLVCLGVYWLVWRVVVRNKISYFRHAALLNMVFCLLAADTCFLGAPFLSP 635

Query: 557 GQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQ--GQGLSTRWLCLIGYGVP 614
           G     C   A L H+ +LA F WM  + L L   ++ VF    +      + L+GY  P
Sbjct: 636 GPRSPLCLAAAFLCHFLYLATFFWMLAQALVLAHQLLFVFHQLAKHRVLPLMVLLGYLCP 695

Query: 615 LLIVGVSAAIY--SKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQK 672
           L + GV+  +Y     Y R   CWLD + G L++F+GPV  II  N ++    + KL + 
Sbjct: 696 LGLAGVTLGLYLPQGQYLREGECWLDGKGGALYTFVGPVLAIIGVNGLVLAMAMLKLLRP 755

Query: 673 FSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLF-IFDDRSLVLTYVFTILNCLQGA 731
                P  +K +    +    +    + G TW  GL  + ++ S V  Y+FTILN LQG 
Sbjct: 756 SLSEGPPAEKRQALLGVIKALLILTPIFGLTWGLGLATLLEEVSTVPHYIFTILNTLQGV 815

Query: 732 FLYLLHCLLNKKVREEYRKWAC 753
           F+ L  CL+++K++E  RK  C
Sbjct: 816 FILLFGCLMDRKIQEALRKRFC 837


>gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo
            sapiens]
          Length = 3312

 Score =  158 bits (399), Expect = 2e-38
 Identities = 109/389 (28%), Positives = 183/389 (47%), Gaps = 40/389 (10%)

Query: 381  YESSIRGVQLRRLSAVNS------IFLSHNNTKE-LNSPILFAFSHLESSDGEAGRDPPA 433
            +++  RG +L +   +NS      +F   N  +  L SPI   F  L++++         
Sbjct: 2424 FQAERRGARLPQNPVMNSPVVSVAVFHGRNFLRGILESPISLEFRLLQTAN--------- 2474

Query: 434  KDVMPGPRQELLCAFWKSD--SDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHY 491
                   R + +C  W     +++ G W    C+++        C+CS   +F +LM   
Sbjct: 2475 -------RSKAICVQWDPPGLAEQHGVWTARDCELVHRNGSHARCRCSRTGTFGVLMDAS 2527

Query: 492  DVEDWK-----LTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGST 546
              E  +     L + T V +A+S+  L+L     L +R ++ +   IH ++   L V   
Sbjct: 2528 PRERLEGDLELLAVFTHVVVAVSVAALVLTAAILLSLRSLKSNVRGIHANVAAALGVAEL 2587

Query: 547  IFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWL 606
            +FL GI     Q  L C  VA LLHY FL+ F W+ ++GL LY + V        + R+ 
Sbjct: 2588 LFLLGIHRTHNQ--LVCTAVAILLHYFFLSTFAWLFVQGLHLYRMQVEPRNVDRGAMRFY 2645

Query: 607  CLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTV 666
              +G+GVP +++G++  +  +GYG P +CW+   +  +WSF GPV  +I+ N  +F    
Sbjct: 2646 HALGWGVPAVLLGLAVGLDPEGYGNPDFCWISVHEPLIWSFAGPVVLVIVMNGTMF---- 2701

Query: 667  WKLTQKFSEINPDMKKLKKARALTI-TAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTIL 725
              L    +  +   ++ KK  ALT+ ++   L L+  +W+FGL   +   L   Y+   L
Sbjct: 2702 --LLAARTSCSTGQREAKKTSALTLRSSFLLLLLVSASWLFGLLAVNHSILAFHYLHAGL 2759

Query: 726  NCLQGAFLYLLHCLLNKKVREEYRKWACL 754
              LQG  + LL C+LN   R  +   ACL
Sbjct: 2760 CGLQGLAVLLLFCVLNADARAAWMP-ACL 2787



 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 20/103 (19%)

Query: 91   CVCSPGYEPVSGAKTFKNESENTCQ-DVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFK 149
            C C PG+            + + C+ ++D C  NP  C++ G C    G YTC C P  +
Sbjct: 1421 CRCPPGF------------TGDFCETELDLCYSNP--CRNGGACARREGGYTCVCRP--R 1464

Query: 150  FIPEDPKVCTDVDECSSGQHQCDSSTVCFNTV-GSYSCRCRPG 191
            F  ED ++ T+   C  G   C +   C +   G + C+C  G
Sbjct: 1465 FTGEDCELDTEAGRCVPG--VCRNGGTCTDAPNGGFRCQCPAG 1505



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 31/110 (28%), Positives = 44/110 (40%), Gaps = 23/110 (20%)

Query: 42   CRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 101
            CRC PGF+   +   T  + C      + P    C     C   EG Y CVC P +    
Sbjct: 1421 CRCPPGFTG--DFCETELDLC-----YSNP----CRNGGACARREGGYTCVCRPRF---- 1465

Query: 102  GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNT-LGSYTCQCLPGFKF 150
                     E+   D +  +  P +C++ GTC +   G + CQC  G  F
Sbjct: 1466 -------TGEDCELDTEAGRCVPGVCRNGGTCTDAPNGGFRCQCPAGGAF 1508



 Score = 39.7 bits (91), Expect = 0.011
 Identities = 27/90 (30%), Positives = 39/90 (43%), Gaps = 22/90 (24%)

Query: 62   CDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQ 121
            C   N CA+     C   +DC +   ++ C C PGY                C  VD C 
Sbjct: 1944 CVVTNACASGP---CPPHADCRDLWQTFSCTCQPGYYGPG------------C--VDACL 1986

Query: 122  QNPRLCKSYGTCVNTLGS---YTCQCLPGF 148
             NP  C++ G+C +  G+   YTC C+ G+
Sbjct: 1987 LNP--CQNQGSCRHLPGAPHGYTCDCVGGY 2014


>gi|119943125 G protein-coupled receptor 64 isoform 3 [Homo sapiens]
          Length = 995

 Score =  154 bits (390), Expect = 2e-37
 Identities = 146/584 (25%), Positives = 248/584 (42%), Gaps = 72/584 (12%)

Query: 205 TVCEDMTFSTWTPPPG----VHSQTLSRFFDKVQDLGRDSKTSSAEVTIQN-VIKLVDEL 259
           TV      +T + PP     V++ ++S   ++V  + +     S E  +   +I  V  L
Sbjct: 327 TVSAPANVNTTSAPPVQTDIVNTSSISDLENQVLQMEKALSLGSLEPNLAGEMINQVSRL 386

Query: 260 MEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSNTELTLMIQERG 319
           + +P D+  LAP     +A +LL  ++DI   L  S      T IS ++  L L +    
Sbjct: 387 LHSPPDM--LAP-----LAQRLLKVVDDIGLQLNFSN-----TTISLTSPSLALAVIRVN 434

Query: 320 DKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLNLHSKKQAELEE 379
             +       A+   N  V+   + P  ++  I    ++   L    + L S+ Q    E
Sbjct: 435 ASSFNTTTFVAQDPANLQVSLETQAPENSIGTITLPSSLMNNLPAHDMELASRVQFNFFE 494

Query: 380 ----IYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDPPAKD 435
                 + S+  + L  +S V S  +++   + L   +     H+  S  E         
Sbjct: 495 TPALFQDPSLENLSL--ISYVISSSVANLTVRNLTRNVTVTLKHINPSQDEL-------- 544

Query: 436 VMPGPRQELLCAFWKSDSDRG-GHWATEGCQVLGSKNGSTTCQCSHLSSFAILM-----A 489
                   + C FW    + G G W+  GC V   +   T C CSHL+SF +L+     +
Sbjct: 545 -------TVRCVFWDLGRNGGRGGWSDNGCSVKDRRLNETICTCSHLTSFGVLLDLSRTS 597

Query: 490 HYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTT-IHLHLCICLFVGSTIF 548
               +   LT IT +G  LS   L + ++T++    I+    + I + LC  L + + +F
Sbjct: 598 VLPAQMMALTFITYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVF 657

Query: 549 LAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLS-TRWLC 607
           L        ++   C  VA  LHY  L +F WM LE   +Y  +V+VF           C
Sbjct: 658 LLDSWIALYKMQGLCISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFC 717

Query: 608 LIGYGVPLLIVGVSAAIYSKGYGRPRY-----------CWLDFEQGFLWSFLGPVTFIIL 656
           ++G+GVP ++V +   I    YG   Y           CW++    F  + +G    I L
Sbjct: 718 IVGWGVPAVVVTIILTISPDNYGLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCVIFL 777

Query: 657 CNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQL-------FLLGCTWVFGLF 709
            N  +F+  + +L +        +KK K+  A   T+I  L       FLLG TW F  F
Sbjct: 778 LNVSMFIVVLVQLCR--------IKKKKQLGAQRKTSIQDLRSIAGLTFLLGITWGFAFF 829

Query: 710 IFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWAC 753
            +   ++   Y+F I N LQG F+++ +C+  + VR+++R++ C
Sbjct: 830 AWGPVNVTFMYLFAIFNTLQGFFIFIFYCVAKENVRKQWRRYLC 873


>gi|119943116 G protein-coupled receptor 64 isoform 2 [Homo sapiens]
          Length = 1003

 Score =  154 bits (390), Expect = 2e-37
 Identities = 146/584 (25%), Positives = 248/584 (42%), Gaps = 72/584 (12%)

Query: 205 TVCEDMTFSTWTPPPG----VHSQTLSRFFDKVQDLGRDSKTSSAEVTIQN-VIKLVDEL 259
           TV      +T + PP     V++ ++S   ++V  + +     S E  +   +I  V  L
Sbjct: 335 TVSAPANVNTTSAPPVQTDIVNTSSISDLENQVLQMEKALSLGSLEPNLAGEMINQVSRL 394

Query: 260 MEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSNTELTLMIQERG 319
           + +P D+  LAP     +A +LL  ++DI   L  S      T IS ++  L L +    
Sbjct: 395 LHSPPDM--LAP-----LAQRLLKVVDDIGLQLNFSN-----TTISLTSPSLALAVIRVN 442

Query: 320 DKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLNLHSKKQAELEE 379
             +       A+   N  V+   + P  ++  I    ++   L    + L S+ Q    E
Sbjct: 443 ASSFNTTTFVAQDPANLQVSLETQAPENSIGTITLPSSLMNNLPAHDMELASRVQFNFFE 502

Query: 380 ----IYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDPPAKD 435
                 + S+  + L  +S V S  +++   + L   +     H+  S  E         
Sbjct: 503 TPALFQDPSLENLSL--ISYVISSSVANLTVRNLTRNVTVTLKHINPSQDEL-------- 552

Query: 436 VMPGPRQELLCAFWKSDSDRG-GHWATEGCQVLGSKNGSTTCQCSHLSSFAILM-----A 489
                   + C FW    + G G W+  GC V   +   T C CSHL+SF +L+     +
Sbjct: 553 -------TVRCVFWDLGRNGGRGGWSDNGCSVKDRRLNETICTCSHLTSFGVLLDLSRTS 605

Query: 490 HYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTT-IHLHLCICLFVGSTIF 548
               +   LT IT +G  LS   L + ++T++    I+    + I + LC  L + + +F
Sbjct: 606 VLPAQMMALTFITYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVF 665

Query: 549 LAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLS-TRWLC 607
           L        ++   C  VA  LHY  L +F WM LE   +Y  +V+VF           C
Sbjct: 666 LLDSWIALYKMQGLCISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFC 725

Query: 608 LIGYGVPLLIVGVSAAIYSKGYGRPRY-----------CWLDFEQGFLWSFLGPVTFIIL 656
           ++G+GVP ++V +   I    YG   Y           CW++    F  + +G    I L
Sbjct: 726 IVGWGVPAVVVTIILTISPDNYGLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCVIFL 785

Query: 657 CNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQL-------FLLGCTWVFGLF 709
            N  +F+  + +L +        +KK K+  A   T+I  L       FLLG TW F  F
Sbjct: 786 LNVSMFIVVLVQLCR--------IKKKKQLGAQRKTSIQDLRSIAGLTFLLGITWGFAFF 837

Query: 710 IFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWAC 753
            +   ++   Y+F I N LQG F+++ +C+  + VR+++R++ C
Sbjct: 838 AWGPVNVTFMYLFAIFNTLQGFFIFIFYCVAKENVRKQWRRYLC 881


>gi|119943120 G protein-coupled receptor 64 isoform 1 [Homo sapiens]
          Length = 1017

 Score =  154 bits (390), Expect = 2e-37
 Identities = 146/584 (25%), Positives = 248/584 (42%), Gaps = 72/584 (12%)

Query: 205 TVCEDMTFSTWTPPPG----VHSQTLSRFFDKVQDLGRDSKTSSAEVTIQN-VIKLVDEL 259
           TV      +T + PP     V++ ++S   ++V  + +     S E  +   +I  V  L
Sbjct: 349 TVSAPANVNTTSAPPVQTDIVNTSSISDLENQVLQMEKALSLGSLEPNLAGEMINQVSRL 408

Query: 260 MEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSNTELTLMIQERG 319
           + +P D+  LAP     +A +LL  ++DI   L  S      T IS ++  L L +    
Sbjct: 409 LHSPPDM--LAP-----LAQRLLKVVDDIGLQLNFSN-----TTISLTSPSLALAVIRVN 456

Query: 320 DKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLNLHSKKQAELEE 379
             +       A+   N  V+   + P  ++  I    ++   L    + L S+ Q    E
Sbjct: 457 ASSFNTTTFVAQDPANLQVSLETQAPENSIGTITLPSSLMNNLPAHDMELASRVQFNFFE 516

Query: 380 ----IYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDPPAKD 435
                 + S+  + L  +S V S  +++   + L   +     H+  S  E         
Sbjct: 517 TPALFQDPSLENLSL--ISYVISSSVANLTVRNLTRNVTVTLKHINPSQDEL-------- 566

Query: 436 VMPGPRQELLCAFWKSDSDRG-GHWATEGCQVLGSKNGSTTCQCSHLSSFAILM-----A 489
                   + C FW    + G G W+  GC V   +   T C CSHL+SF +L+     +
Sbjct: 567 -------TVRCVFWDLGRNGGRGGWSDNGCSVKDRRLNETICTCSHLTSFGVLLDLSRTS 619

Query: 490 HYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTT-IHLHLCICLFVGSTIF 548
               +   LT IT +G  LS   L + ++T++    I+    + I + LC  L + + +F
Sbjct: 620 VLPAQMMALTFITYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVF 679

Query: 549 LAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLS-TRWLC 607
           L        ++   C  VA  LHY  L +F WM LE   +Y  +V+VF           C
Sbjct: 680 LLDSWIALYKMQGLCISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFC 739

Query: 608 LIGYGVPLLIVGVSAAIYSKGYGRPRY-----------CWLDFEQGFLWSFLGPVTFIIL 656
           ++G+GVP ++V +   I    YG   Y           CW++    F  + +G    I L
Sbjct: 740 IVGWGVPAVVVTIILTISPDNYGLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCVIFL 799

Query: 657 CNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQL-------FLLGCTWVFGLF 709
            N  +F+  + +L +        +KK K+  A   T+I  L       FLLG TW F  F
Sbjct: 800 LNVSMFIVVLVQLCR--------IKKKKQLGAQRKTSIQDLRSIAGLTFLLGITWGFAFF 851

Query: 710 IFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWAC 753
            +   ++   Y+F I N LQG F+++ +C+  + VR+++R++ C
Sbjct: 852 AWGPVNVTFMYLFAIFNTLQGFFIFIFYCVAKENVRKQWRRYLC 895


>gi|119943129 G protein-coupled receptor 64 isoform 4 [Homo sapiens]
          Length = 1014

 Score =  154 bits (390), Expect = 2e-37
 Identities = 146/584 (25%), Positives = 248/584 (42%), Gaps = 72/584 (12%)

Query: 205 TVCEDMTFSTWTPPPG----VHSQTLSRFFDKVQDLGRDSKTSSAEVTIQN-VIKLVDEL 259
           TV      +T + PP     V++ ++S   ++V  + +     S E  +   +I  V  L
Sbjct: 346 TVSAPANVNTTSAPPVQTDIVNTSSISDLENQVLQMEKALSLGSLEPNLAGEMINQVSRL 405

Query: 260 MEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSNTELTLMIQERG 319
           + +P D+  LAP     +A +LL  ++DI   L  S      T IS ++  L L +    
Sbjct: 406 LHSPPDM--LAP-----LAQRLLKVVDDIGLQLNFSN-----TTISLTSPSLALAVIRVN 453

Query: 320 DKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLNLHSKKQAELEE 379
             +       A+   N  V+   + P  ++  I    ++   L    + L S+ Q    E
Sbjct: 454 ASSFNTTTFVAQDPANLQVSLETQAPENSIGTITLPSSLMNNLPAHDMELASRVQFNFFE 513

Query: 380 ----IYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDPPAKD 435
                 + S+  + L  +S V S  +++   + L   +     H+  S  E         
Sbjct: 514 TPALFQDPSLENLSL--ISYVISSSVANLTVRNLTRNVTVTLKHINPSQDEL-------- 563

Query: 436 VMPGPRQELLCAFWKSDSDRG-GHWATEGCQVLGSKNGSTTCQCSHLSSFAILM-----A 489
                   + C FW    + G G W+  GC V   +   T C CSHL+SF +L+     +
Sbjct: 564 -------TVRCVFWDLGRNGGRGGWSDNGCSVKDRRLNETICTCSHLTSFGVLLDLSRTS 616

Query: 490 HYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTT-IHLHLCICLFVGSTIF 548
               +   LT IT +G  LS   L + ++T++    I+    + I + LC  L + + +F
Sbjct: 617 VLPAQMMALTFITYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVF 676

Query: 549 LAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLS-TRWLC 607
           L        ++   C  VA  LHY  L +F WM LE   +Y  +V+VF           C
Sbjct: 677 LLDSWIALYKMQGLCISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFC 736

Query: 608 LIGYGVPLLIVGVSAAIYSKGYGRPRY-----------CWLDFEQGFLWSFLGPVTFIIL 656
           ++G+GVP ++V +   I    YG   Y           CW++    F  + +G    I L
Sbjct: 737 IVGWGVPAVVVTIILTISPDNYGLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCVIFL 796

Query: 657 CNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQL-------FLLGCTWVFGLF 709
            N  +F+  + +L +        +KK K+  A   T+I  L       FLLG TW F  F
Sbjct: 797 LNVSMFIVVLVQLCR--------IKKKKQLGAQRKTSIQDLRSIAGLTFLLGITWGFAFF 848

Query: 710 IFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWAC 753
            +   ++   Y+F I N LQG F+++ +C+  + VR+++R++ C
Sbjct: 849 AWGPVNVTFMYLFAIFNTLQGFFIFIFYCVAKENVRKQWRRYLC 892


>gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [Homo
            sapiens]
          Length = 1584

 Score =  150 bits (379), Expect = 4e-36
 Identities = 95/297 (31%), Positives = 157/297 (52%), Gaps = 12/297 (4%)

Query: 457  GHWATEGCQVLGSKNGSTTCQCSHLSSFAILM---AHYDVEDWKLTLITR-VGLALSLFC 512
            G W+  GC+ +      T C C  LS+FAIL    A  ++E   L  +T  VG  +S   
Sbjct: 902  GPWSWRGCRTVPLDALRTRCLCDRLSTFAILAQLSADANMEKATLPSVTLIVGCGVSSLT 961

Query: 513  LLLCILTFLLV-RPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLH 571
            LL+ ++ ++ V R I+  R+ I ++ C+ +   + + L G      +V   C LVA  LH
Sbjct: 962  LLMLVIIYVSVWRYIRSERSVILINFCLSIISSNALILIGQTQTRNKVV--CTLVAAFLH 1019

Query: 572  YCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIY-SKGYG 630
            + FL++FCW+  E  + Y  V    + + +  R+LCL G+G+P L+V +S     +KGY 
Sbjct: 1020 FFFLSSFCWVLTEAWQSYMAVTGHLRNRLIRKRFLCL-GWGLPALVVAISVGFTKAKGYS 1078

Query: 631  RPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALT 690
               YCWL  E G L++F+GP   ++L N VI +    KL  K  +   D K  ++A A  
Sbjct: 1079 TMNYCWLSLEGGLLYAFVGPAAAVVLVNMVIGILVFNKLVSK--DGITDKKLKERAGASL 1136

Query: 691  ITAIAQLFLLGCTWVFG-LFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVRE 746
             ++   L LL  TW+   L + D RS +   +F + + L+G  + ++HC+L ++V++
Sbjct: 1137 WSSCVVLPLLALTWMSAVLAVTDRRSALFQILFAVFDSLEGFVIVMVHCILRREVQD 1193


>gi|59710093 G-protein coupled receptor 112 [Homo sapiens]
          Length = 3080

 Score =  148 bits (374), Expect = 2e-35
 Identities = 97/325 (29%), Positives = 155/325 (47%), Gaps = 24/325 (7%)

Query: 446  CAFWKSDSDRG-GHWATEGCQVLGSKNGSTTCQCSHLSSFAILM-----AHYDVEDWKLT 499
            CAFW  +++ G G W + GC+V  +    T CQC HL+ F +LM         V +  L 
Sbjct: 2685 CAFWDFENNNGLGGWNSSGCKVKETNVNYTICQCDHLTHFGVLMDLSRSTVDSVNEQILA 2744

Query: 500  LITRVGLALSLFCLLLCILTFLLVRPIQGSRTT-IHLHLCICLFVGSTIFLAGIENEGGQ 558
            LIT  G  +S   L + ++T++    ++      I ++LC  L + + +FL        Q
Sbjct: 2745 LITYTGCGISSIFLGVAVVTYIAFHKLRKDYPAKILINLCTALLMLNLVFLINSWLSSFQ 2804

Query: 559  VGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLS-TRWLCLIGYGVPLLI 617
                C   A  LHY  L +F WM LE + +Y  +V+VF     +     CL+G+G+P ++
Sbjct: 2805 KVGVCITAAVALHYFLLVSFTWMGLEAVHMYLALVKVFNIYIPNYILKFCLVGWGIPAIM 2864

Query: 618  VGVSAAIYSKGYGR----PRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKF 673
            V ++ ++    YG       +CW+  +  F  S +     I L N  +F T + +L    
Sbjct: 2865 VAITVSVKKDLYGTLSPTTPFCWIKDDSIFYISVVAYFCLIFLMNLSMFCTVLVQLNSVK 2924

Query: 674  SEINPDMKK-----LKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCL 728
            S+I    +K     LK   +LT       FLLG TW F  F +        Y+F I N L
Sbjct: 2925 SQIQKTRRKMILHDLKGTMSLT-------FLLGLTWGFAFFAWGPMRNFFLYLFAIFNTL 2977

Query: 729  QGAFLYLLHCLLNKKVREEYRKWAC 753
            QG F+++ HC++ + VRE+++   C
Sbjct: 2978 QGFFIFVFHCVMKESVREQWQIHLC 3002


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.136    0.438 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,717,437
Number of Sequences: 37866
Number of extensions: 1564488
Number of successful extensions: 7662
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 186
Number of HSP's successfully gapped in prelim test: 111
Number of HSP's that attempted gapping in prelim test: 3942
Number of HSP's gapped (non-prelim): 1286
length of query: 786
length of database: 18,247,518
effective HSP length: 110
effective length of query: 676
effective length of database: 14,082,258
effective search space: 9519606408
effective search space used: 9519606408
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.