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Search of human proteins with 68303547
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|68303547 argininosuccinate lyase isoform 2 [Homo sapiens]
(444 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|68303547 argininosuccinate lyase isoform 2 [Homo sapiens] 880 0.0
gi|31541964 argininosuccinate lyase isoform 1 [Homo sapiens] 868 0.0
gi|68303542 argininosuccinate lyase isoform 1 [Homo sapiens] 868 0.0
gi|68303549 argininosuccinate lyase isoform 3 [Homo sapiens] 805 0.0
gi|95089461 discs large homolog 5 [Homo sapiens] 33 0.68
gi|239754171 PREDICTED: chromosome 5 open reading frame 50 [Homo... 31 2.0
gi|169168128 PREDICTED: chromosome 5 open reading frame 50 [Homo... 31 2.0
gi|239742721 PREDICTED: chromosome 5 open reading frame 50 [Homo... 31 2.0
gi|111548650 family with sequence similarity 170, member A [Homo... 31 2.6
gi|197313748 SET domain containing 2 [Homo sapiens] 30 3.4
gi|6005942 valosin-containing protein [Homo sapiens] 29 9.8
>gi|68303547 argininosuccinate lyase isoform 2 [Homo sapiens]
Length = 444
Score = 880 bits (2273), Expect = 0.0
Identities = 444/444 (100%), Positives = 444/444 (100%)
Query: 1 MASESGKLWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEM 60
MASESGKLWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEM
Sbjct: 1 MASESGKLWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEM 60
Query: 61 DQILHGLDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTD 120
DQILHGLDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTD
Sbjct: 61 DQILHGLDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTD 120
Query: 121 LRLWMRQTCSTLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVAL 180
LRLWMRQTCSTLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVAL
Sbjct: 121 LRLWMRQTCSTLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVAL 180
Query: 181 TRDSERLLEVRKRINVLPLGSGAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVA 240
TRDSERLLEVRKRINVLPLGSGAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVA
Sbjct: 181 TRDSERLLEVRKRINVLPLGSGAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVA 240
Query: 241 EFLFWASLCMTHLSRMAEDLILYCTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKA 300
EFLFWASLCMTHLSRMAEDLILYCTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKA
Sbjct: 241 EFLFWASLCMTHLSRMAEDLILYCTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKA 300
Query: 301 GRVFGREDKEAVFEVSDTMSAVLQVATGVISTLQIHQENMGQALSPDMLATDLAYYLVRK 360
GRVFGREDKEAVFEVSDTMSAVLQVATGVISTLQIHQENMGQALSPDMLATDLAYYLVRK
Sbjct: 301 GRVFGREDKEAVFEVSDTMSAVLQVATGVISTLQIHQENMGQALSPDMLATDLAYYLVRK 360
Query: 361 GMPFRQAHEASGKAVFMAETKGVALNQLSLQELQTISPLFSGDVICVWDYGHSVEQYGAL 420
GMPFRQAHEASGKAVFMAETKGVALNQLSLQELQTISPLFSGDVICVWDYGHSVEQYGAL
Sbjct: 361 GMPFRQAHEASGKAVFMAETKGVALNQLSLQELQTISPLFSGDVICVWDYGHSVEQYGAL 420
Query: 421 GGTARSSVDWQIRQVRALLQAQQA 444
GGTARSSVDWQIRQVRALLQAQQA
Sbjct: 421 GGTARSSVDWQIRQVRALLQAQQA 444
>gi|31541964 argininosuccinate lyase isoform 1 [Homo sapiens]
Length = 464
Score = 868 bits (2242), Expect = 0.0
Identities = 444/464 (95%), Positives = 444/464 (95%), Gaps = 20/464 (4%)
Query: 1 MASESGKLWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEM 60
MASESGKLWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEM
Sbjct: 1 MASESGKLWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEM 60
Query: 61 DQILHGLDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTD 120
DQILHGLDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTD
Sbjct: 61 DQILHGLDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTD 120
Query: 121 LRLWMRQTCSTLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVAL 180
LRLWMRQTCSTLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVAL
Sbjct: 121 LRLWMRQTCSTLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVAL 180
Query: 181 TRDSERLLEVRKRINVLPLGSGAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVA 240
TRDSERLLEVRKRINVLPLGSGAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVA
Sbjct: 181 TRDSERLLEVRKRINVLPLGSGAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVA 240
Query: 241 EFLFWASLCMTHLSRMAEDLILYCTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKA 300
EFLFWASLCMTHLSRMAEDLILYCTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKA
Sbjct: 241 EFLFWASLCMTHLSRMAEDLILYCTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKA 300
Query: 301 GRVFGR--------------------EDKEAVFEVSDTMSAVLQVATGVISTLQIHQENM 340
GRVFGR EDKEAVFEVSDTMSAVLQVATGVISTLQIHQENM
Sbjct: 301 GRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMSAVLQVATGVISTLQIHQENM 360
Query: 341 GQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNQLSLQELQTISPLF 400
GQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNQLSLQELQTISPLF
Sbjct: 361 GQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNQLSLQELQTISPLF 420
Query: 401 SGDVICVWDYGHSVEQYGALGGTARSSVDWQIRQVRALLQAQQA 444
SGDVICVWDYGHSVEQYGALGGTARSSVDWQIRQVRALLQAQQA
Sbjct: 421 SGDVICVWDYGHSVEQYGALGGTARSSVDWQIRQVRALLQAQQA 464
>gi|68303542 argininosuccinate lyase isoform 1 [Homo sapiens]
Length = 464
Score = 868 bits (2242), Expect = 0.0
Identities = 444/464 (95%), Positives = 444/464 (95%), Gaps = 20/464 (4%)
Query: 1 MASESGKLWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEM 60
MASESGKLWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEM
Sbjct: 1 MASESGKLWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEM 60
Query: 61 DQILHGLDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTD 120
DQILHGLDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTD
Sbjct: 61 DQILHGLDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTD 120
Query: 121 LRLWMRQTCSTLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVAL 180
LRLWMRQTCSTLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVAL
Sbjct: 121 LRLWMRQTCSTLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVAL 180
Query: 181 TRDSERLLEVRKRINVLPLGSGAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVA 240
TRDSERLLEVRKRINVLPLGSGAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVA
Sbjct: 181 TRDSERLLEVRKRINVLPLGSGAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVA 240
Query: 241 EFLFWASLCMTHLSRMAEDLILYCTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKA 300
EFLFWASLCMTHLSRMAEDLILYCTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKA
Sbjct: 241 EFLFWASLCMTHLSRMAEDLILYCTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKA 300
Query: 301 GRVFGR--------------------EDKEAVFEVSDTMSAVLQVATGVISTLQIHQENM 340
GRVFGR EDKEAVFEVSDTMSAVLQVATGVISTLQIHQENM
Sbjct: 301 GRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMSAVLQVATGVISTLQIHQENM 360
Query: 341 GQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNQLSLQELQTISPLF 400
GQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNQLSLQELQTISPLF
Sbjct: 361 GQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNQLSLQELQTISPLF 420
Query: 401 SGDVICVWDYGHSVEQYGALGGTARSSVDWQIRQVRALLQAQQA 444
SGDVICVWDYGHSVEQYGALGGTARSSVDWQIRQVRALLQAQQA
Sbjct: 421 SGDVICVWDYGHSVEQYGALGGTARSSVDWQIRQVRALLQAQQA 464
>gi|68303549 argininosuccinate lyase isoform 3 [Homo sapiens]
Length = 438
Score = 805 bits (2080), Expect = 0.0
Identities = 418/464 (90%), Positives = 418/464 (90%), Gaps = 46/464 (9%)
Query: 1 MASESGKLWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEM 60
MASESGKLWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEM
Sbjct: 1 MASESGKLWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEM 60
Query: 61 DQILHGLDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTD 120
DQILHGLDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTD
Sbjct: 61 DQILHGLDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTD 120
Query: 121 LRLWMRQTCSTLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVAL 180
LRLWMRQTCSTLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWIL
Sbjct: 121 LRLWMRQTCSTLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWIL------ 174
Query: 181 TRDSERLLEVRKRINVLPLGSGAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVA 240
SGAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVA
Sbjct: 175 --------------------SGAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVA 214
Query: 241 EFLFWASLCMTHLSRMAEDLILYCTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKA 300
EFLFWASLCMTHLSRMAEDLILYCTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKA
Sbjct: 215 EFLFWASLCMTHLSRMAEDLILYCTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKA 274
Query: 301 GRVFGR--------------------EDKEAVFEVSDTMSAVLQVATGVISTLQIHQENM 340
GRVFGR EDKEAVFEVSDTMSAVLQVATGVISTLQIHQENM
Sbjct: 275 GRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMSAVLQVATGVISTLQIHQENM 334
Query: 341 GQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNQLSLQELQTISPLF 400
GQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNQLSLQELQTISPLF
Sbjct: 335 GQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNQLSLQELQTISPLF 394
Query: 401 SGDVICVWDYGHSVEQYGALGGTARSSVDWQIRQVRALLQAQQA 444
SGDVICVWDYGHSVEQYGALGGTARSSVDWQIRQVRALLQAQQA
Sbjct: 395 SGDVICVWDYGHSVEQYGALGGTARSSVDWQIRQVRALLQAQQA 438
>gi|95089461 discs large homolog 5 [Homo sapiens]
Length = 1919
Score = 32.7 bits (73), Expect = 0.68
Identities = 31/106 (29%), Positives = 45/106 (42%), Gaps = 17/106 (16%)
Query: 55 LTKAEMDQILHGLDKVAEEWAQGTFKLNSNDEDIHTANE-----RRLKELIGATAGKLHT 109
L +E DQ++ LDK+ E KL S+ + ANE R++K+ + AG
Sbjct: 434 LIMSERDQVISELDKLQTEVELAESKLKSSTSEKKAANEEMEALRQIKDTVTMDAG---- 489
Query: 110 GRSRNDQVVTDLRLWMRQTCSTLSGLLWELIRTMVDRAEAERDVLF 155
R ++ V LR + C L L E D A+ RD F
Sbjct: 490 ---RANKEVEILRKQCKALCQELKEALQE-----ADVAKCRRDWAF 527
>gi|239754171 PREDICTED: chromosome 5 open reading frame 50 [Homo
sapiens]
Length = 371
Score = 31.2 bits (69), Expect = 2.0
Identities = 27/107 (25%), Positives = 42/107 (39%), Gaps = 14/107 (13%)
Query: 79 FKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTDLRLWM---------RQTC 129
++ N E+ LKE + + KL + +Q+ DL LW+ + C
Sbjct: 218 YQTNEPSEEPIKTIRNWLKEKLHVFSEKLEEEVQQLEQLAWDLELWLDALLGEPHQEEHC 277
Query: 130 STLSGLLWE----LIRTMVD-RAEAERDVLFPGYTHLQRAQPIRWSH 171
ST LWE L R D E+ + P T + ++Q W H
Sbjct: 278 STYKSHLWEWAWALGREHKDFPVESGKRAELPAQTDMSQSQGSSWKH 324
>gi|169168128 PREDICTED: chromosome 5 open reading frame 50 [Homo
sapiens]
Length = 371
Score = 31.2 bits (69), Expect = 2.0
Identities = 27/107 (25%), Positives = 42/107 (39%), Gaps = 14/107 (13%)
Query: 79 FKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTDLRLWM---------RQTC 129
++ N E+ LKE + + KL + +Q+ DL LW+ + C
Sbjct: 218 YQTNEPSEEPIKTIRNWLKEKLHVFSEKLEEEVQQLEQLAWDLELWLDALLGEPHQEEHC 277
Query: 130 STLSGLLWE----LIRTMVD-RAEAERDVLFPGYTHLQRAQPIRWSH 171
ST LWE L R D E+ + P T + ++Q W H
Sbjct: 278 STYKSHLWEWAWALGREHKDFPVESGKRAELPAQTDMSQSQGSSWKH 324
>gi|239742721 PREDICTED: chromosome 5 open reading frame 50 [Homo
sapiens]
Length = 371
Score = 31.2 bits (69), Expect = 2.0
Identities = 27/107 (25%), Positives = 42/107 (39%), Gaps = 14/107 (13%)
Query: 79 FKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTDLRLWM---------RQTC 129
++ N E+ LKE + + KL + +Q+ DL LW+ + C
Sbjct: 218 YQTNEPSEEPIKTIRNWLKEKLHVFSEKLEEEVQQLEQLAWDLELWLDALLGEPHQEEHC 277
Query: 130 STLSGLLWE----LIRTMVD-RAEAERDVLFPGYTHLQRAQPIRWSH 171
ST LWE L R D E+ + P T + ++Q W H
Sbjct: 278 STYKSHLWEWAWALGREHKDFPVESGKRAELPAQTDMSQSQGSSWKH 324
>gi|111548650 family with sequence similarity 170, member A [Homo
sapiens]
Length = 329
Score = 30.8 bits (68), Expect = 2.6
Identities = 17/59 (28%), Positives = 32/59 (54%), Gaps = 2/59 (3%)
Query: 50 EKAGLLTKAEMDQILHGLDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIGATAGKLH 108
EK G ++K++ D + G +VA+ W+QG ++ S E + R +LI + ++H
Sbjct: 20 EKGGGMSKSQEDALQPGSTRVAKGWSQGVGEVTSTSEYCSCVSSSR--KLIHSGIQRIH 76
>gi|197313748 SET domain containing 2 [Homo sapiens]
Length = 2564
Score = 30.4 bits (67), Expect = 3.4
Identities = 21/80 (26%), Positives = 43/80 (53%), Gaps = 6/80 (7%)
Query: 273 LSDAYSTGSSLMPQKKNPDSLEL-IRSKAGRVFGREDKEAVFEVSDTMSAVLQVATGVIS 331
L +A G+S++P+++ + L R + G V +D E VF D ++ ++ + GV
Sbjct: 959 LQEAQEEGNSILPERRGRPEISLDERGEGGHVHTSDDSEVVFSSCD-LNLTMEDSDGV-- 1015
Query: 332 TLQIHQENMGQALSPDMLAT 351
T + ++ G A P++++T
Sbjct: 1016 TYALKCDSSGHA--PEIVST 1033
>gi|6005942 valosin-containing protein [Homo sapiens]
Length = 806
Score = 28.9 bits (63), Expect = 9.8
Identities = 22/66 (33%), Positives = 31/66 (46%), Gaps = 12/66 (18%)
Query: 283 LMPQKKNPDSLELIRSKAGRVFGREDKEAVFEVSDTMSAVLQVATGVISTLQIHQENMGQ 342
+M P+S++ A R FGR D+E + D ATG + LQIH +NM
Sbjct: 343 VMAATNRPNSID----PALRRFGRFDREVDIGIPD--------ATGRLEILQIHTKNMKL 390
Query: 343 ALSPDM 348
A D+
Sbjct: 391 ADDVDL 396
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.132 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,034,524
Number of Sequences: 37866
Number of extensions: 603746
Number of successful extensions: 1258
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1249
Number of HSP's gapped (non-prelim): 11
length of query: 444
length of database: 18,247,518
effective HSP length: 105
effective length of query: 339
effective length of database: 14,271,588
effective search space: 4838068332
effective search space used: 4838068332
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.