Guide to the Human Genome
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Search of human proteins with 68160945

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|68160945 sterol-C5-desaturase [Homo sapiens]
         (299 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|68160945 sterol-C5-desaturase [Homo sapiens]                       635   0.0  
gi|68160941 sterol-C5-desaturase [Homo sapiens]                       635   0.0  
gi|62865628 sterol-C4-methyl oxidase-like isoform 2 [Homo sapiens]     81   1e-15
gi|5803157 sterol-C4-methyl oxidase-like isoform 1 [Homo sapiens]      81   1e-15
gi|146198575 hypothetical protein LOC10826 isoform 2 [Homo sapiens]    63   3e-10
gi|4502499 cholesterol 25-hydroxylase [Homo sapiens]                   51   1e-06
gi|51972212 transmembrane protein 195 [Homo sapiens]                   44   2e-04
gi|40789306 zinc finger protein 365 isoform C [Homo sapiens]           30   3.4  
gi|55743086 alpha-1,3-mannosyltransferase ALG3 isoform d [Homo s...    28   7.5  
gi|5031953 alpha-1,3-mannosyltransferase ALG3 isoform a [Homo sa...    28   7.5  
gi|52317096 olfactory receptor, family 4, subfamily X, member 1 ...    28   7.5  
gi|222446642 solute carrier family 36, member 3 isoform 1 [Homo ...    28   9.8  
gi|222446640 solute carrier family 36, member 3 isoform 2 [Homo ...    28   9.8  
gi|44888835 ATPase, class I, type 8B, member 3 [Homo sapiens]          28   9.8  
gi|125660451 MAS-related GPR, member X1 [Homo sapiens]                 28   9.8  

>gi|68160945 sterol-C5-desaturase [Homo sapiens]
          Length = 299

 Score =  635 bits (1639), Expect = 0.0
 Identities = 299/299 (100%), Positives = 299/299 (100%)

Query: 1   MDLVLRVADYYFFTPYVYPATWPEDDIFRQAISLLIVTNVGAYILYFFCATLSYYFVFDH 60
           MDLVLRVADYYFFTPYVYPATWPEDDIFRQAISLLIVTNVGAYILYFFCATLSYYFVFDH
Sbjct: 1   MDLVLRVADYYFFTPYVYPATWPEDDIFRQAISLLIVTNVGAYILYFFCATLSYYFVFDH 60

Query: 61  ALMKHPQFLKNQVRREIKFTVQALPWISILTVALFLLEIRGYSKLHDDLGEFPYGLFELV 120
           ALMKHPQFLKNQVRREIKFTVQALPWISILTVALFLLEIRGYSKLHDDLGEFPYGLFELV
Sbjct: 61  ALMKHPQFLKNQVRREIKFTVQALPWISILTVALFLLEIRGYSKLHDDLGEFPYGLFELV 120

Query: 121 VSIISFLFFTDMFIYWIHRGLHHRLVYKRLHKPHHIWKIPTPFASHAFHPIDGFLQSLPY 180
           VSIISFLFFTDMFIYWIHRGLHHRLVYKRLHKPHHIWKIPTPFASHAFHPIDGFLQSLPY
Sbjct: 121 VSIISFLFFTDMFIYWIHRGLHHRLVYKRLHKPHHIWKIPTPFASHAFHPIDGFLQSLPY 180

Query: 181 HIYPFIFPLHKVVYLSLYILVNIWTISIHDGDFRVPQILQPFINGSAHHTDHHMFFDYNY 240
           HIYPFIFPLHKVVYLSLYILVNIWTISIHDGDFRVPQILQPFINGSAHHTDHHMFFDYNY
Sbjct: 181 HIYPFIFPLHKVVYLSLYILVNIWTISIHDGDFRVPQILQPFINGSAHHTDHHMFFDYNY 240

Query: 241 GQYFTLWDRIGGSFKNPSSFEGKGPLSYVKEMTEGKRSSHSGNGCKNEKLFNGEFTKTE 299
           GQYFTLWDRIGGSFKNPSSFEGKGPLSYVKEMTEGKRSSHSGNGCKNEKLFNGEFTKTE
Sbjct: 241 GQYFTLWDRIGGSFKNPSSFEGKGPLSYVKEMTEGKRSSHSGNGCKNEKLFNGEFTKTE 299


>gi|68160941 sterol-C5-desaturase [Homo sapiens]
          Length = 299

 Score =  635 bits (1639), Expect = 0.0
 Identities = 299/299 (100%), Positives = 299/299 (100%)

Query: 1   MDLVLRVADYYFFTPYVYPATWPEDDIFRQAISLLIVTNVGAYILYFFCATLSYYFVFDH 60
           MDLVLRVADYYFFTPYVYPATWPEDDIFRQAISLLIVTNVGAYILYFFCATLSYYFVFDH
Sbjct: 1   MDLVLRVADYYFFTPYVYPATWPEDDIFRQAISLLIVTNVGAYILYFFCATLSYYFVFDH 60

Query: 61  ALMKHPQFLKNQVRREIKFTVQALPWISILTVALFLLEIRGYSKLHDDLGEFPYGLFELV 120
           ALMKHPQFLKNQVRREIKFTVQALPWISILTVALFLLEIRGYSKLHDDLGEFPYGLFELV
Sbjct: 61  ALMKHPQFLKNQVRREIKFTVQALPWISILTVALFLLEIRGYSKLHDDLGEFPYGLFELV 120

Query: 121 VSIISFLFFTDMFIYWIHRGLHHRLVYKRLHKPHHIWKIPTPFASHAFHPIDGFLQSLPY 180
           VSIISFLFFTDMFIYWIHRGLHHRLVYKRLHKPHHIWKIPTPFASHAFHPIDGFLQSLPY
Sbjct: 121 VSIISFLFFTDMFIYWIHRGLHHRLVYKRLHKPHHIWKIPTPFASHAFHPIDGFLQSLPY 180

Query: 181 HIYPFIFPLHKVVYLSLYILVNIWTISIHDGDFRVPQILQPFINGSAHHTDHHMFFDYNY 240
           HIYPFIFPLHKVVYLSLYILVNIWTISIHDGDFRVPQILQPFINGSAHHTDHHMFFDYNY
Sbjct: 181 HIYPFIFPLHKVVYLSLYILVNIWTISIHDGDFRVPQILQPFINGSAHHTDHHMFFDYNY 240

Query: 241 GQYFTLWDRIGGSFKNPSSFEGKGPLSYVKEMTEGKRSSHSGNGCKNEKLFNGEFTKTE 299
           GQYFTLWDRIGGSFKNPSSFEGKGPLSYVKEMTEGKRSSHSGNGCKNEKLFNGEFTKTE
Sbjct: 241 GQYFTLWDRIGGSFKNPSSFEGKGPLSYVKEMTEGKRSSHSGNGCKNEKLFNGEFTKTE 299


>gi|62865628 sterol-C4-methyl oxidase-like isoform 2 [Homo sapiens]
          Length = 162

 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 45/135 (33%), Positives = 70/135 (51%), Gaps = 2/135 (1%)

Query: 131 DMFIYWIHRGLHHRLVYKRLHKPHHIWKIPTPFASHAFHPIDGFLQSLPYHIYPFIFPLH 190
           D + Y++HR LHH+ +YK +HK HH ++ P    +   HP++  +    + I   +   H
Sbjct: 19  DTWHYFLHRLLHHKRIYKYIHKVHHEFQAPFGMEAEYAHPLETLILGTGFFIGIVLLCDH 78

Query: 191 KVVYLSLYILVNIWTISIHDG-DFRV-PQILQPFINGSAHHTDHHMFFDYNYGQYFTLWD 248
            ++  +   +  + TI +H G D  + P  L PF  GS HH  HHM F  NY   FT WD
Sbjct: 79  VILLWAWVTIRLLETIDVHSGYDIPLNPLNLIPFYAGSRHHDFHHMNFIGNYASTFTWWD 138

Query: 249 RIGGSFKNPSSFEGK 263
           RI G+    +++  K
Sbjct: 139 RIFGTDSQYNAYNEK 153


>gi|5803157 sterol-C4-methyl oxidase-like isoform 1 [Homo sapiens]
          Length = 293

 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 45/135 (33%), Positives = 70/135 (51%), Gaps = 2/135 (1%)

Query: 131 DMFIYWIHRGLHHRLVYKRLHKPHHIWKIPTPFASHAFHPIDGFLQSLPYHIYPFIFPLH 190
           D + Y++HR LHH+ +YK +HK HH ++ P    +   HP++  +    + I   +   H
Sbjct: 150 DTWHYFLHRLLHHKRIYKYIHKVHHEFQAPFGMEAEYAHPLETLILGTGFFIGIVLLCDH 209

Query: 191 KVVYLSLYILVNIWTISIHDG-DFRV-PQILQPFINGSAHHTDHHMFFDYNYGQYFTLWD 248
            ++  +   +  + TI +H G D  + P  L PF  GS HH  HHM F  NY   FT WD
Sbjct: 210 VILLWAWVTIRLLETIDVHSGYDIPLNPLNLIPFYAGSRHHDFHHMNFIGNYASTFTWWD 269

Query: 249 RIGGSFKNPSSFEGK 263
           RI G+    +++  K
Sbjct: 270 RIFGTDSQYNAYNEK 284


>gi|146198575 hypothetical protein LOC10826 isoform 2 [Homo sapiens]
          Length = 333

 Score = 63.2 bits (152), Expect = 3e-10
 Identities = 47/158 (29%), Positives = 68/158 (43%), Gaps = 15/158 (9%)

Query: 108 DLGEFPYGLFELVVSIISFLFFTDMFIYWIHRGLHHRLVYKRLHKPHHIWKIPTPFASHA 167
           +L  F + L EL +    F    ++  Y+ HR LHH   YK++HK HH W  P    S  
Sbjct: 164 ELPTFHWFLLELAI----FTLIEEVLFYYSHRLLHHPTFYKKIHKKHHEWTAPIGVISLY 219

Query: 168 FHPIDGFLQS-LPYHIYPFIFPLHKVVYLSLYILVNIWTISIHDGDFRVPQILQPFINGS 226
            HPI+  + + LP  + P +   H       + L  I T   H G         PF+   
Sbjct: 220 AHPIEHAVSNMLPVIVGPLVMGSHLSSITMWFSLALIITTISHCG------YHLPFLPSP 273

Query: 227 AHHTDHHMFFDYNYGQYFTLWDRIGGS---FKNPSSFE 261
             H  HH+ F+  YG    L D + G+   FK   ++E
Sbjct: 274 EFHDYHHLKFNQCYGVLGVL-DHLHGTDTMFKQTKAYE 310


>gi|4502499 cholesterol 25-hydroxylase [Homo sapiens]
          Length = 272

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 40/140 (28%), Positives = 64/140 (45%), Gaps = 13/140 (9%)

Query: 127 LFFTDMFIYWIHRGLHHRL--VYKRLHKPHHIWKIPTPFASHAFHPIDGFLQSLPYHIYP 184
           LF  + F++ +   LHH++  +Y+  HK HH        A+      + F       +  
Sbjct: 134 LFDMEFFVWHL---LHHKVPWLYRTFHKVHHQNSSSFALATQYMSVWELFSLGFFDMMNV 190

Query: 185 FIFPLHKVVYLSLYILVNIW-TISIHDGDFRVP---QILQPF--INGSAHHTDHHMFFDY 238
            +   H +  L+ ++ VNIW ++  H G +  P     L PF    G  HH  HH  F+ 
Sbjct: 191 TLLGCHPLTTLTFHV-VNIWLSVEDHSG-YNFPWSTHRLVPFGWYGGVVHHDLHHSHFNC 248

Query: 239 NYGQYFTLWDRIGGSFKNPS 258
           N+  YFT WD+I G+ +  S
Sbjct: 249 NFAPYFTHWDKILGTLRTAS 268


>gi|51972212 transmembrane protein 195 [Homo sapiens]
          Length = 445

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 34/132 (25%), Positives = 50/132 (37%), Gaps = 12/132 (9%)

Query: 131 DMFIYWIHRGLHHRLVYKRLHKPHHI---WKIPTPFASHAFHPIDGFLQSLPYHIYPFIF 187
           D   YW HR  H   +    H+ HH    + + T            ++   P  +  FI 
Sbjct: 125 DFGYYWFHRMAHEVNIMWAGHQTHHSSEDYNLSTALRQSVLQIYTSWIFYSPLAL--FIP 182

Query: 188 PLHKVVYLSLYILVNIWTISIHDGDFRVPQILQPFINGSAHHTDHH----MFFDYNYGQY 243
           P    V+L   +L   W   IH         L+  +N  +HH  HH       D NY   
Sbjct: 183 PSVYAVHLQFNLLYQFW---IHTEVINNLGPLELILNTPSHHRVHHGRNRYCIDKNYAGV 239

Query: 244 FTLWDRIGGSFK 255
             +WD+I G+F+
Sbjct: 240 LIIWDKIFGTFE 251


>gi|40789306 zinc finger protein 365 isoform C [Homo sapiens]
          Length = 462

 Score = 29.6 bits (65), Expect = 3.4
 Identities = 22/69 (31%), Positives = 31/69 (44%), Gaps = 6/69 (8%)

Query: 166 HAFHPIDGFLQSLPYHIYPFIF--PLHKVVYLS-LYILVNIWTISIHDGDFRVPQILQPF 222
           H  H + G   S   H   F+   P+  ++  S L+IL N WT S     F    +L PF
Sbjct: 331 HINHHLSGLKDS---HCLVFLQAPPVPWIILASFLWILGNPWTSSTATAGFSQIWVLFPF 387

Query: 223 INGSAHHTD 231
             G+ HH +
Sbjct: 388 CGGTFHHNE 396


>gi|55743086 alpha-1,3-mannosyltransferase ALG3 isoform d [Homo
           sapiens]
          Length = 390

 Score = 28.5 bits (62), Expect = 7.5
 Identities = 20/85 (23%), Positives = 37/85 (43%), Gaps = 8/85 (9%)

Query: 123 IISFLFFTDMFIYWIHRGLHHRLVYKRLHK-PHHIWKIPTPFASHAFHPIDGFLQSLPYH 181
           I+S LF ++       R LH++      H  P+ +W +P  + +H    +   L  L ++
Sbjct: 290 IVSTLFTSNFIGICFSRSLHYQFYVWYFHTLPYLLWAMPARWLTHLLRLLVLGLIELSWN 349

Query: 182 IYP-------FIFPLHKVVYLSLYI 199
            YP        +   H V+ L L++
Sbjct: 350 TYPSTSCSSAALHICHAVILLQLWL 374


>gi|5031953 alpha-1,3-mannosyltransferase ALG3 isoform a [Homo
           sapiens]
          Length = 438

 Score = 28.5 bits (62), Expect = 7.5
 Identities = 20/85 (23%), Positives = 37/85 (43%), Gaps = 8/85 (9%)

Query: 123 IISFLFFTDMFIYWIHRGLHHRLVYKRLHK-PHHIWKIPTPFASHAFHPIDGFLQSLPYH 181
           I+S LF ++       R LH++      H  P+ +W +P  + +H    +   L  L ++
Sbjct: 338 IVSTLFTSNFIGICFSRSLHYQFYVWYFHTLPYLLWAMPARWLTHLLRLLVLGLIELSWN 397

Query: 182 IYP-------FIFPLHKVVYLSLYI 199
            YP        +   H V+ L L++
Sbjct: 398 TYPSTSCSSAALHICHAVILLQLWL 422


>gi|52317096 olfactory receptor, family 4, subfamily X, member 1
           [Homo sapiens]
          Length = 305

 Score = 28.5 bits (62), Expect = 7.5
 Identities = 18/59 (30%), Positives = 27/59 (45%), Gaps = 3/59 (5%)

Query: 7   VADYYFFTPYVYPATWPEDDIFRQAISLLIVTNVGAYILYFFCATLSYYFVFDHALMKH 65
           + D+YF   +        D  F   ISLLI+TN G+  +  F   ++ Y +  H L  H
Sbjct: 171 IMDHYFCDVHPVLELACADTFF---ISLLIITNGGSISVVSFFVLMASYLIILHFLRSH 226


>gi|222446642 solute carrier family 36, member 3 isoform 1 [Homo
           sapiens]
          Length = 511

 Score = 28.1 bits (61), Expect = 9.8
 Identities = 22/76 (28%), Positives = 36/76 (47%), Gaps = 6/76 (7%)

Query: 33  SLLIVTNVGAYILYFFCATLSYYFVFDHALMKHPQFLKNQVRREIKFTVQALPWISILTV 92
           +L ++ N   ++L+F  A     F F+   M  P  LKNQ++   +F+      +SI+ +
Sbjct: 284 NLPLMANWKTFLLFFGTAI----FTFEGVGMVLP--LKNQMKHPQQFSFVLYLGMSIVII 337

Query: 93  ALFLLEIRGYSKLHDD 108
              LL   GY K   D
Sbjct: 338 LYILLGTLGYMKFGSD 353


>gi|222446640 solute carrier family 36, member 3 isoform 2 [Homo
           sapiens]
          Length = 470

 Score = 28.1 bits (61), Expect = 9.8
 Identities = 22/76 (28%), Positives = 36/76 (47%), Gaps = 6/76 (7%)

Query: 33  SLLIVTNVGAYILYFFCATLSYYFVFDHALMKHPQFLKNQVRREIKFTVQALPWISILTV 92
           +L ++ N   ++L+F  A     F F+   M  P  LKNQ++   +F+      +SI+ +
Sbjct: 243 NLPLMANWKTFLLFFGTAI----FTFEGVGMVLP--LKNQMKHPQQFSFVLYLGMSIVII 296

Query: 93  ALFLLEIRGYSKLHDD 108
              LL   GY K   D
Sbjct: 297 LYILLGTLGYMKFGSD 312


>gi|44888835 ATPase, class I, type 8B, member 3 [Homo sapiens]
          Length = 1300

 Score = 28.1 bits (61), Expect = 9.8
 Identities = 13/30 (43%), Positives = 17/30 (56%)

Query: 81  VQALPWISILTVALFLLEIRGYSKLHDDLG 110
           +  LPW S+ T  + LL IR    L DD+G
Sbjct: 177 ISTLPWFSLSTPMVCLLFIRATRDLVDDMG 206


>gi|125660451 MAS-related GPR, member X1 [Homo sapiens]
          Length = 322

 Score = 28.1 bits (61), Expect = 9.8
 Identities = 21/100 (21%), Positives = 42/100 (42%), Gaps = 14/100 (14%)

Query: 114 YGLFELVVSIISFLFFTDMFIYWIHRGLHHRLVYKRLHKPHHIWKIPTPFASHAFHPIDG 173
           + ++ L ++   FLF +   IY +            +  PH I KI  P    ++     
Sbjct: 61  FSIYILNLAAADFLFLSGRLIYSL---------LSFISIPHTISKILYPVMMFSYFAGLS 111

Query: 174 FLQSLPYH-----IYPFIFPLHKVVYLSLYILVNIWTISI 208
           FL ++        ++P  +  H+  +LS  + V +W +S+
Sbjct: 112 FLSAVSTERCLSVLWPIWYRCHRPTHLSAVVCVLLWALSL 151


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.329    0.146    0.480 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,663,394
Number of Sequences: 37866
Number of extensions: 517749
Number of successful extensions: 1238
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1225
Number of HSP's gapped (non-prelim): 16
length of query: 299
length of database: 18,247,518
effective HSP length: 102
effective length of query: 197
effective length of database: 14,385,186
effective search space: 2833881642
effective search space used: 2833881642
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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