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Search of human proteins with 66932893
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|66932893 TM2 domain containing 2 isoform b [Homo sapiens]
(171 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|66932897 TM2 domain containing 2 isoform b [Homo sapiens] 367 e-102
gi|66932895 TM2 domain containing 2 isoform b [Homo sapiens] 367 e-102
gi|66932893 TM2 domain containing 2 isoform b [Homo sapiens] 367 e-102
gi|17865797 TM2 domain containing 2 isoform a [Homo sapiens] 306 4e-84
gi|91807119 TM2 domain containing 3 isoform b [Homo sapiens] 65 3e-11
gi|91807117 TM2 domain containing 3 isoform a [Homo sapiens] 65 3e-11
gi|14042945 beta-amyloid binding protein precursor [Homo sapiens] 48 4e-06
gi|94680985 cyclin J-like [Homo sapiens] 29 2.3
gi|167466252 transmembrane protease, serine 11A isoform 2 [Homo ... 28 5.0
gi|167466250 transmembrane protease, serine 11A isoform 1 [Homo ... 28 5.0
gi|14591924 Sec23 homolog B [Homo sapiens] 27 6.6
gi|14591926 Sec23 homolog B [Homo sapiens] 27 6.6
gi|14591928 Sec23 homolog B [Homo sapiens] 27 6.6
gi|38202214 SEC23-related protein A [Homo sapiens] 27 8.6
gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor ... 27 8.6
>gi|66932897 TM2 domain containing 2 isoform b [Homo sapiens]
Length = 171
Score = 367 bits (942), Expect = e-102
Identities = 171/171 (100%), Positives = 171/171 (100%)
Query: 1 MKKCLLPVLITCMQTAICKDRMMMIMILLVNYRPDEFIECEDPVDHVGNATASQELGYGC 60
MKKCLLPVLITCMQTAICKDRMMMIMILLVNYRPDEFIECEDPVDHVGNATASQELGYGC
Sbjct: 1 MKKCLLPVLITCMQTAICKDRMMMIMILLVNYRPDEFIECEDPVDHVGNATASQELGYGC 60
Query: 61 LKFGGQAYSDVEHTSVQCHALDGIECASPRTFLRENKPCIKYTGHYFITTLLYSFFLGCF 120
LKFGGQAYSDVEHTSVQCHALDGIECASPRTFLRENKPCIKYTGHYFITTLLYSFFLGCF
Sbjct: 61 LKFGGQAYSDVEHTSVQCHALDGIECASPRTFLRENKPCIKYTGHYFITTLLYSFFLGCF 120
Query: 121 GVDRFCLGHTGTAVGKLLTLGGLGIWWFVDLILLITGGLMPSDGSNWCTVY 171
GVDRFCLGHTGTAVGKLLTLGGLGIWWFVDLILLITGGLMPSDGSNWCTVY
Sbjct: 121 GVDRFCLGHTGTAVGKLLTLGGLGIWWFVDLILLITGGLMPSDGSNWCTVY 171
>gi|66932895 TM2 domain containing 2 isoform b [Homo sapiens]
Length = 171
Score = 367 bits (942), Expect = e-102
Identities = 171/171 (100%), Positives = 171/171 (100%)
Query: 1 MKKCLLPVLITCMQTAICKDRMMMIMILLVNYRPDEFIECEDPVDHVGNATASQELGYGC 60
MKKCLLPVLITCMQTAICKDRMMMIMILLVNYRPDEFIECEDPVDHVGNATASQELGYGC
Sbjct: 1 MKKCLLPVLITCMQTAICKDRMMMIMILLVNYRPDEFIECEDPVDHVGNATASQELGYGC 60
Query: 61 LKFGGQAYSDVEHTSVQCHALDGIECASPRTFLRENKPCIKYTGHYFITTLLYSFFLGCF 120
LKFGGQAYSDVEHTSVQCHALDGIECASPRTFLRENKPCIKYTGHYFITTLLYSFFLGCF
Sbjct: 61 LKFGGQAYSDVEHTSVQCHALDGIECASPRTFLRENKPCIKYTGHYFITTLLYSFFLGCF 120
Query: 121 GVDRFCLGHTGTAVGKLLTLGGLGIWWFVDLILLITGGLMPSDGSNWCTVY 171
GVDRFCLGHTGTAVGKLLTLGGLGIWWFVDLILLITGGLMPSDGSNWCTVY
Sbjct: 121 GVDRFCLGHTGTAVGKLLTLGGLGIWWFVDLILLITGGLMPSDGSNWCTVY 171
>gi|66932893 TM2 domain containing 2 isoform b [Homo sapiens]
Length = 171
Score = 367 bits (942), Expect = e-102
Identities = 171/171 (100%), Positives = 171/171 (100%)
Query: 1 MKKCLLPVLITCMQTAICKDRMMMIMILLVNYRPDEFIECEDPVDHVGNATASQELGYGC 60
MKKCLLPVLITCMQTAICKDRMMMIMILLVNYRPDEFIECEDPVDHVGNATASQELGYGC
Sbjct: 1 MKKCLLPVLITCMQTAICKDRMMMIMILLVNYRPDEFIECEDPVDHVGNATASQELGYGC 60
Query: 61 LKFGGQAYSDVEHTSVQCHALDGIECASPRTFLRENKPCIKYTGHYFITTLLYSFFLGCF 120
LKFGGQAYSDVEHTSVQCHALDGIECASPRTFLRENKPCIKYTGHYFITTLLYSFFLGCF
Sbjct: 61 LKFGGQAYSDVEHTSVQCHALDGIECASPRTFLRENKPCIKYTGHYFITTLLYSFFLGCF 120
Query: 121 GVDRFCLGHTGTAVGKLLTLGGLGIWWFVDLILLITGGLMPSDGSNWCTVY 171
GVDRFCLGHTGTAVGKLLTLGGLGIWWFVDLILLITGGLMPSDGSNWCTVY
Sbjct: 121 GVDRFCLGHTGTAVGKLLTLGGLGIWWFVDLILLITGGLMPSDGSNWCTVY 171
>gi|17865797 TM2 domain containing 2 isoform a [Homo sapiens]
Length = 214
Score = 306 bits (785), Expect = 4e-84
Identities = 140/145 (96%), Positives = 143/145 (98%)
Query: 27 ILLVNYRPDEFIECEDPVDHVGNATASQELGYGCLKFGGQAYSDVEHTSVQCHALDGIEC 86
++L +Y PDEFIECEDPVDHVGNATASQELGYGCLKFGGQAYSDVEHTSVQCHALDGIEC
Sbjct: 70 VILCSYLPDEFIECEDPVDHVGNATASQELGYGCLKFGGQAYSDVEHTSVQCHALDGIEC 129
Query: 87 ASPRTFLRENKPCIKYTGHYFITTLLYSFFLGCFGVDRFCLGHTGTAVGKLLTLGGLGIW 146
ASPRTFLRENKPCIKYTGHYFITTLLYSFFLGCFGVDRFCLGHTGTAVGKLLTLGGLGIW
Sbjct: 130 ASPRTFLRENKPCIKYTGHYFITTLLYSFFLGCFGVDRFCLGHTGTAVGKLLTLGGLGIW 189
Query: 147 WFVDLILLITGGLMPSDGSNWCTVY 171
WFVDLILLITGGLMPSDGSNWCTVY
Sbjct: 190 WFVDLILLITGGLMPSDGSNWCTVY 214
>gi|91807119 TM2 domain containing 3 isoform b [Homo sapiens]
Length = 221
Score = 65.1 bits (157), Expect = 3e-11
Identities = 36/88 (40%), Positives = 48/88 (54%), Gaps = 1/88 (1%)
Query: 78 CHALDGIECASPRTFLRENKPCIKYTGHYFITTLLYSFFLGCFGVDRFCLGHTGTAVGKL 137
C D + C RTF + C G+ + T L S LG FG DRF LG +GKL
Sbjct: 132 CTVRDHVHCLGNRTFPKMLY-CNWTGGYKWSTALALSITLGGFGADRFYLGQWREGLGKL 190
Query: 138 LTLGGLGIWWFVDLILLITGGLMPSDGS 165
+ GGLGIW +D++L+ G + P+DGS
Sbjct: 191 FSFGGLGIWTLIDVLLIGVGYVGPADGS 218
>gi|91807117 TM2 domain containing 3 isoform a [Homo sapiens]
Length = 247
Score = 65.1 bits (157), Expect = 3e-11
Identities = 36/88 (40%), Positives = 48/88 (54%), Gaps = 1/88 (1%)
Query: 78 CHALDGIECASPRTFLRENKPCIKYTGHYFITTLLYSFFLGCFGVDRFCLGHTGTAVGKL 137
C D + C RTF + C G+ + T L S LG FG DRF LG +GKL
Sbjct: 158 CTVRDHVHCLGNRTFPKMLY-CNWTGGYKWSTALALSITLGGFGADRFYLGQWREGLGKL 216
Query: 138 LTLGGLGIWWFVDLILLITGGLMPSDGS 165
+ GGLGIW +D++L+ G + P+DGS
Sbjct: 217 FSFGGLGIWTLIDVLLIGVGYVGPADGS 244
>gi|14042945 beta-amyloid binding protein precursor [Homo sapiens]
Length = 207
Score = 48.1 bits (113), Expect = 4e-06
Identities = 26/73 (35%), Positives = 37/73 (50%)
Query: 99 CIKYTGHYFITTLLYSFFLGCFGVDRFCLGHTGTAVGKLLTLGGLGIWWFVDLILLITGG 158
C G+ + + S FLG G DRF LG+ + K T+G GI +D IL+
Sbjct: 113 CRNVNGYSYKVAVALSLFLGWLGADRFYLGYPALGLLKFCTVGFCGIGSLIDFILISMQI 172
Query: 159 LMPSDGSNWCTVY 171
+ PSDGS++ Y
Sbjct: 173 VGPSDGSSYIIDY 185
>gi|94680985 cyclin J-like [Homo sapiens]
Length = 435
Score = 28.9 bits (63), Expect = 2.3
Identities = 17/49 (34%), Positives = 20/49 (40%), Gaps = 10/49 (20%)
Query: 89 PRTFLRENKPCIKYTGHYFITTLL-----YSF-----FLGCFGVDRFCL 127
P T R+ K C+K HYF+ L Y F C G R CL
Sbjct: 218 PTTCPRKTKECLKEYAHYFLEVTLQDHIFYKFQPSVVAAACVGASRICL 266
>gi|167466252 transmembrane protease, serine 11A isoform 2 [Homo
sapiens]
Length = 418
Score = 27.7 bits (60), Expect = 5.0
Identities = 21/96 (21%), Positives = 41/96 (42%), Gaps = 18/96 (18%)
Query: 57 GYGCLKFGGQAYSDVEHTSVQCHALDGIECASPRTFLRENKPCIKYTGHYFITTLLYSFF 116
G+G L +GG++ +D+ V+ + D C P+ + + KP + G+
Sbjct: 310 GFGALYYGGESQNDLREARVKIISDD--VCKQPQVYGNDIKPGMFCAGY----------- 356
Query: 117 LGCFGVDRFCLGHTGTAVGKLLTLGGLGIWWFVDLI 152
G+ C G +G G L+T W+ + ++
Sbjct: 357 --MEGIYDACRGDSG---GPLVTRDLKDTWYLIGIV 387
>gi|167466250 transmembrane protease, serine 11A isoform 1 [Homo
sapiens]
Length = 421
Score = 27.7 bits (60), Expect = 5.0
Identities = 21/96 (21%), Positives = 41/96 (42%), Gaps = 18/96 (18%)
Query: 57 GYGCLKFGGQAYSDVEHTSVQCHALDGIECASPRTFLRENKPCIKYTGHYFITTLLYSFF 116
G+G L +GG++ +D+ V+ + D C P+ + + KP + G+
Sbjct: 313 GFGALYYGGESQNDLREARVKIISDD--VCKQPQVYGNDIKPGMFCAGY----------- 359
Query: 117 LGCFGVDRFCLGHTGTAVGKLLTLGGLGIWWFVDLI 152
G+ C G +G G L+T W+ + ++
Sbjct: 360 --MEGIYDACRGDSG---GPLVTRDLKDTWYLIGIV 390
>gi|14591924 Sec23 homolog B [Homo sapiens]
Length = 767
Score = 27.3 bits (59), Expect = 6.6
Identities = 13/35 (37%), Positives = 17/35 (48%)
Query: 74 TSVQCHALDGIECASPRTFLRENKPCIKYTGHYFI 108
T+ H +D CA +T L E K C TG Y +
Sbjct: 340 TAANGHCIDIYACALDQTGLLEMKCCANLTGGYMV 374
>gi|14591926 Sec23 homolog B [Homo sapiens]
Length = 767
Score = 27.3 bits (59), Expect = 6.6
Identities = 13/35 (37%), Positives = 17/35 (48%)
Query: 74 TSVQCHALDGIECASPRTFLRENKPCIKYTGHYFI 108
T+ H +D CA +T L E K C TG Y +
Sbjct: 340 TAANGHCIDIYACALDQTGLLEMKCCANLTGGYMV 374
>gi|14591928 Sec23 homolog B [Homo sapiens]
Length = 767
Score = 27.3 bits (59), Expect = 6.6
Identities = 13/35 (37%), Positives = 17/35 (48%)
Query: 74 TSVQCHALDGIECASPRTFLRENKPCIKYTGHYFI 108
T+ H +D CA +T L E K C TG Y +
Sbjct: 340 TAANGHCIDIYACALDQTGLLEMKCCANLTGGYMV 374
>gi|38202214 SEC23-related protein A [Homo sapiens]
Length = 765
Score = 26.9 bits (58), Expect = 8.6
Identities = 22/63 (34%), Positives = 27/63 (42%), Gaps = 9/63 (14%)
Query: 79 HALDGIECASPRTFLRENKPCIKYTGHY------FITTLLYSFFLGCFGVD---RFCLGH 129
H +D CA +T L E K C TG Y F T+L F F D +F +G
Sbjct: 343 HVIDIYACALDQTGLLEMKCCPNLTGGYMVMGDSFNTSLFKQTFQRVFTKDMHGQFKMGF 402
Query: 130 TGT 132
GT
Sbjct: 403 GGT 405
>gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor [Homo
sapiens]
Length = 1336
Score = 26.9 bits (58), Expect = 8.6
Identities = 12/29 (41%), Positives = 13/29 (44%)
Query: 139 TLGGLGIWWFVDLILLITGGLMPSDGSNW 167
+LGGL WWF D L P G W
Sbjct: 1125 SLGGLEPWWFADFPYPYAERLGPPPGRYW 1153
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.328 0.144 0.485
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,912,023
Number of Sequences: 37866
Number of extensions: 293113
Number of successful extensions: 572
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 561
Number of HSP's gapped (non-prelim): 15
length of query: 171
length of database: 18,247,518
effective HSP length: 95
effective length of query: 76
effective length of database: 14,650,248
effective search space: 1113418848
effective search space used: 1113418848
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.