Search of human proteins with 66529396

Search of human proteins with 66529396

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|66529396 paraoxonase 2 isoform 2 [Homo sapiens]
         (342 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|66529396 paraoxonase 2 isoform 2 [Homo sapiens]                    689   0.0  
gi|66529294 paraoxonase 2 isoform 1 [Homo sapiens]                    681   0.0  
gi|19923106 paraoxonase 1 precursor [Homo sapiens]                    469   e-132
gi|29788996 paraoxonase 3 [Homo sapiens]                              457   e-129
gi|48717495 chondroitin polymerizing factor 2 [Homo sapiens]           33   0.37 
gi|149944516 tet oncogene family member 3 [Homo sapiens]               33   0.48 
gi|24308201 chromosome 20 open reading frame 3 [Homo sapiens]          32   1.1  
gi|42476013 NHL repeat containing 2 [Homo sapiens]                     31   1.4  
gi|157502171 sorting nexin 19 [Homo sapiens]                           30   2.4  
gi|23510338 ubiquitin-activating enzyme E1 [Homo sapiens]              29   5.3  
gi|23510340 ubiquitin-activating enzyme E1 [Homo sapiens]              29   5.3  
gi|4826724 zygin 1 isoform 1 [Homo sapiens]                            29   7.0  
gi|12025680 zygin 1 isoform 2 [Homo sapiens]                           29   7.0  
gi|226442779 jumonji domain containing 1A [Homo sapiens]               29   7.0  
gi|20357522 jumonji domain containing 1A [Homo sapiens]                29   7.0  

>gi|66529396 paraoxonase 2 isoform 2 [Homo sapiens]
          Length = 342

 Score =  689 bits (1779), Expect = 0.0
 Identities = 342/342 (100%), Positives = 342/342 (100%)

Query: 1   MGRLVAVGLLGIALALLGERLLALRNRLKASREVESVDLPHCHLIKGIEAGSEDIDILPN 60
           MGRLVAVGLLGIALALLGERLLALRNRLKASREVESVDLPHCHLIKGIEAGSEDIDILPN
Sbjct: 1   MGRLVAVGLLGIALALLGERLLALRNRLKASREVESVDLPHCHLIKGIEAGSEDIDILPN 60

Query: 61  GLAFFSVGLKFPGLHSFAPDKPGGILMMDLKEEKPRARELRISRGFDLASFNPHGISTFI 120
           GLAFFSVGLKFPGLHSFAPDKPGGILMMDLKEEKPRARELRISRGFDLASFNPHGISTFI
Sbjct: 61  GLAFFSVGLKFPGLHSFAPDKPGGILMMDLKEEKPRARELRISRGFDLASFNPHGISTFI 120

Query: 121 DNEFKNTVEIFKFEEAENSLLHLKTVKHELLPSVNDITAVGPAHFYATNDHYFSDPFLKY 180
           DNEFKNTVEIFKFEEAENSLLHLKTVKHELLPSVNDITAVGPAHFYATNDHYFSDPFLKY
Sbjct: 121 DNEFKNTVEIFKFEEAENSLLHLKTVKHELLPSVNDITAVGPAHFYATNDHYFSDPFLKY 180

Query: 181 LETYLNLHWANVVYYSPNEVKVVAEGFDSANGINISPDDKYIYVADILAHEIHVLEKHTN 240
           LETYLNLHWANVVYYSPNEVKVVAEGFDSANGINISPDDKYIYVADILAHEIHVLEKHTN
Sbjct: 181 LETYLNLHWANVVYYSPNEVKVVAEGFDSANGINISPDDKYIYVADILAHEIHVLEKHTN 240

Query: 241 MNLTQLKVLELDTLVDNLSIDPSSGDIWVGCHPNGQKLFVYDPNNPPSSEVLRIQNILSE 300
           MNLTQLKVLELDTLVDNLSIDPSSGDIWVGCHPNGQKLFVYDPNNPPSSEVLRIQNILSE
Sbjct: 241 MNLTQLKVLELDTLVDNLSIDPSSGDIWVGCHPNGQKLFVYDPNNPPSSEVLRIQNILSE 300

Query: 301 KPTVTTVYANNGSVLQGSSVASVYDGKLLIGTLYHRALYCEL 342
           KPTVTTVYANNGSVLQGSSVASVYDGKLLIGTLYHRALYCEL
Sbjct: 301 KPTVTTVYANNGSVLQGSSVASVYDGKLLIGTLYHRALYCEL 342


>gi|66529294 paraoxonase 2 isoform 1 [Homo sapiens]
          Length = 354

 Score =  681 bits (1756), Expect = 0.0
 Identities = 342/354 (96%), Positives = 342/354 (96%), Gaps = 12/354 (3%)

Query: 1   MGRLVAVGLLGIALALLGERLLALRNRLKASREVESVDLPHCHLIKGIEAGSEDIDILPN 60
           MGRLVAVGLLGIALALLGERLLALRNRLKASREVESVDLPHCHLIKGIEAGSEDIDILPN
Sbjct: 1   MGRLVAVGLLGIALALLGERLLALRNRLKASREVESVDLPHCHLIKGIEAGSEDIDILPN 60

Query: 61  GLAFFSVGLKFPGLHSFAPDKPGGILMMDLKEEKPRARELRISRGFDLASFNPHGISTFI 120
           GLAFFSVGLKFPGLHSFAPDKPGGILMMDLKEEKPRARELRISRGFDLASFNPHGISTFI
Sbjct: 61  GLAFFSVGLKFPGLHSFAPDKPGGILMMDLKEEKPRARELRISRGFDLASFNPHGISTFI 120

Query: 121 DN------------EFKNTVEIFKFEEAENSLLHLKTVKHELLPSVNDITAVGPAHFYAT 168
           DN            EFKNTVEIFKFEEAENSLLHLKTVKHELLPSVNDITAVGPAHFYAT
Sbjct: 121 DNDDTVYLFVVNHPEFKNTVEIFKFEEAENSLLHLKTVKHELLPSVNDITAVGPAHFYAT 180

Query: 169 NDHYFSDPFLKYLETYLNLHWANVVYYSPNEVKVVAEGFDSANGINISPDDKYIYVADIL 228
           NDHYFSDPFLKYLETYLNLHWANVVYYSPNEVKVVAEGFDSANGINISPDDKYIYVADIL
Sbjct: 181 NDHYFSDPFLKYLETYLNLHWANVVYYSPNEVKVVAEGFDSANGINISPDDKYIYVADIL 240

Query: 229 AHEIHVLEKHTNMNLTQLKVLELDTLVDNLSIDPSSGDIWVGCHPNGQKLFVYDPNNPPS 288
           AHEIHVLEKHTNMNLTQLKVLELDTLVDNLSIDPSSGDIWVGCHPNGQKLFVYDPNNPPS
Sbjct: 241 AHEIHVLEKHTNMNLTQLKVLELDTLVDNLSIDPSSGDIWVGCHPNGQKLFVYDPNNPPS 300

Query: 289 SEVLRIQNILSEKPTVTTVYANNGSVLQGSSVASVYDGKLLIGTLYHRALYCEL 342
           SEVLRIQNILSEKPTVTTVYANNGSVLQGSSVASVYDGKLLIGTLYHRALYCEL
Sbjct: 301 SEVLRIQNILSEKPTVTTVYANNGSVLQGSSVASVYDGKLLIGTLYHRALYCEL 354


>gi|19923106 paraoxonase 1 precursor [Homo sapiens]
          Length = 355

 Score =  469 bits (1206), Expect = e-132
 Identities = 226/355 (63%), Positives = 280/355 (78%), Gaps = 13/355 (3%)

Query: 1   MGRLVAVGLLGIALALLGERLLALRNRLKASREVESVDLPHCHLIKGIEAGSEDIDILPN 60
           M +L+A+ LLG+ LAL      + + RL A REV+ V+LP+C+L+KGIE GSED++ILPN
Sbjct: 1   MAKLIALTLLGMGLALFRNHQSSYQTRLNALREVQPVELPNCNLVKGIETGSEDLEILPN 60

Query: 61  GLAFFSVGLKFPGLHSFAPDKPGGILMMDLKEEKPRARELRISRG-FDLASFNPHGISTF 119
           GLAF S GLK+PG+ SF P+ PG IL+MDL EE P   EL I+   FD++SFNPHGISTF
Sbjct: 61  GLAFISSGLKYPGIKSFNPNSPGKILLMDLNEEDPTVLELGITGSKFDVSSFNPHGISTF 120

Query: 120 IDNE------------FKNTVEIFKFEEAENSLLHLKTVKHELLPSVNDITAVGPAHFYA 167
            D +             K+TVE+FKF+E E SLLHLKT++H+LLP++NDI AVGP HFY 
Sbjct: 121 TDEDNAMYLLVVNHPDAKSTVELFKFQEEEKSLLHLKTIRHKLLPNLNDIVAVGPEHFYG 180

Query: 168 TNDHYFSDPFLKYLETYLNLHWANVVYYSPNEVKVVAEGFDSANGINISPDDKYIYVADI 227
           TNDHYF DP+L+  E YL L W+ VVYYSP+EV+VVAEGFD ANGINISPD KY+Y+A++
Sbjct: 181 TNDHYFLDPYLQSWEMYLGLAWSYVVYYSPSEVRVVAEGFDFANGINISPDGKYVYIAEL 240

Query: 228 LAHEIHVLEKHTNMNLTQLKVLELDTLVDNLSIDPSSGDIWVGCHPNGQKLFVYDPNNPP 287
           LAH+IHV EKH N  LT LK L+ +TLVDN+S+DP +GD+WVGCHPNG K+F YD  NPP
Sbjct: 241 LAHKIHVYEKHANWTLTPLKSLDFNTLVDNISVDPETGDLWVGCHPNGMKIFFYDSENPP 300

Query: 288 SSEVLRIQNILSEKPTVTTVYANNGSVLQGSSVASVYDGKLLIGTLYHRALYCEL 342
           +SEVLRIQNIL+E+P VT VYA NG+VLQGS+VASVY GKLLIGT++H+ALYCEL
Sbjct: 301 ASEVLRIQNILTEEPKVTQVYAENGTVLQGSTVASVYKGKLLIGTVFHKALYCEL 355


>gi|29788996 paraoxonase 3 [Homo sapiens]
          Length = 354

 Score =  457 bits (1175), Expect = e-129
 Identities = 222/354 (62%), Positives = 276/354 (77%), Gaps = 12/354 (3%)

Query: 1   MGRLVAVGLLGIALALLGERLLALRNRLKASREVESVDLPHCHLIKGIEAGSEDIDILPN 60
           MG+LVA+ LLG+ L+L+GE  LA R R+ ASREVE V+  +CHLI+ +E+GSEDIDILP+
Sbjct: 1   MGKLVALVLLGVGLSLVGEMFLAFRERVNASREVEPVEPENCHLIEELESGSEDIDILPS 60

Query: 61  GLAFFSVGLKFPGLHSFAPDKPGGILMMDLKEEKPRARELRISRGFDLASFNPHGISTFI 120
           GLAF S GLK+PG+ +FAPD+PG I +MDL E+ PRA+ L IS GFD   FNPHGIS FI
Sbjct: 61  GLAFISSGLKYPGMPNFAPDEPGKIFLMDLNEQNPRAQALEISGGFDKELFNPHGISIFI 120

Query: 121 DNE------------FKNTVEIFKFEEAENSLLHLKTVKHELLPSVNDITAVGPAHFYAT 168
           D +             K+TVEIFKFEE + SL++LKT+KHELL SVNDI  +GP  FYAT
Sbjct: 121 DKDNTVYLYVVNHPHMKSTVEIFKFEEQQRSLVYLKTIKHELLKSVNDIVVLGPEQFYAT 180

Query: 169 NDHYFSDPFLKYLETYLNLHWANVVYYSPNEVKVVAEGFDSANGINISPDDKYIYVADIL 228
            DHYF++  L + E  L+L W  V++YSP EVKVVA+GF SANGI +S D KY+YVAD+ 
Sbjct: 181 RDHYFTNSLLSFFEMILDLRWTYVLFYSPREVKVVAKGFCSANGITVSADQKYVYVADVA 240

Query: 229 AHEIHVLEKHTNMNLTQLKVLELDTLVDNLSIDPSSGDIWVGCHPNGQKLFVYDPNNPPS 288
           A  IH++EKH N +LTQLKV++L TLVDNL++DP++GDI  GCHPN  KL  Y+P +PP 
Sbjct: 241 AKNIHIMEKHDNWDLTQLKVIQLGTLVDNLTVDPATGDILAGCHPNPMKLLNYNPEDPPG 300

Query: 289 SEVLRIQNILSEKPTVTTVYANNGSVLQGSSVASVYDGKLLIGTLYHRALYCEL 342
           SEVLRIQN+LSEKP V+TVYANNGSVLQG+SVASVY GK+LIGT++H+ LYCEL
Sbjct: 301 SEVLRIQNVLSEKPRVSTVYANNGSVLQGTSVASVYHGKILIGTVFHKTLYCEL 354


>gi|48717495 chondroitin polymerizing factor 2 [Homo sapiens]
          Length = 772

 Score = 33.1 bits (74), Expect = 0.37
 Identities = 20/55 (36%), Positives = 28/55 (50%), Gaps = 1/55 (1%)

Query: 45  IKGIEAGSEDIDILPNGLAFFSVGLKFPGLHSFAPDKPGGILMMDLKEEKPRARE 99
           + G  AG E+ + L  GL    V L+F GLH F   +PG +    L++  PR  E
Sbjct: 686 LAGELAGQEEEEAL-EGLEVMDVFLRFSGLHLFRAVEPGLVQKFSLRDCSPRLSE 739


>gi|149944516 tet oncogene family member 3 [Homo sapiens]
          Length = 1660

 Score = 32.7 bits (73), Expect = 0.48
 Identities = 20/60 (33%), Positives = 30/60 (50%), Gaps = 9/60 (15%)

Query: 46  KGIEAGSEDIDILPNGLAFFSVGLKFPGLHSFAPDKPGGI---------LMMDLKEEKPR 96
           +G  AGSED+D L   LA    G+K P  +   P+ P  +         ++M+  EE+PR
Sbjct: 109 EGCSAGSEDLDTLQTALALARHGMKPPNCNCDGPECPDYLEWLEGKIKSVVMEGGEERPR 168


>gi|24308201 chromosome 20 open reading frame 3 [Homo sapiens]
          Length = 416

 Score = 31.6 bits (70), Expect = 1.1
 Identities = 42/168 (25%), Positives = 71/168 (42%), Gaps = 17/168 (10%)

Query: 113 PHGISTFIDNEFKNTVEIFKFEEAENSLLHLKT-VKHELLPSVNDITAVGPAHFYATNDH 171
           P+G + F+ + +K   E+  ++     LL  +T ++ + +  VND+T             
Sbjct: 159 PNG-TLFVADAYKGLFEVNPWKREVKLLLSSETPIEGKNMSFVNDLTVTQDGRKI----- 212

Query: 172 YFSDPFLKYLET-YLNLHW-----ANVVYYSP--NEVKVVAEGFDSANGINISPDDKYIY 223
           YF+D   K+    YL L         ++ Y     EVKV+ +     NG+ +SP + ++ 
Sbjct: 213 YFTDSSSKWQRRDYLLLVMEGTDDGRLLEYDTVTREVKVLLDQLRFPNGVQLSPAEDFVL 272

Query: 224 VAD-ILAHEIHVLEKHTNMNLTQLKVLELDTLVDNLSIDPSSGDIWVG 270
           VA+  +A    V           L V  +    DN+    SSG  WVG
Sbjct: 273 VAETTMARIRRVYVSGLMKGGADLFVENMPGFPDNIR-PSSSGGYWVG 319


>gi|42476013 NHL repeat containing 2 [Homo sapiens]
          Length = 726

 Score = 31.2 bits (69), Expect = 1.4
 Identities = 27/110 (24%), Positives = 51/110 (46%), Gaps = 11/110 (10%)

Query: 212 GINISPDDKYIYVADILAHEIHVLEKHTNMNLTQLKVLELDTLVDNLSIDPSS----GDI 267
           G+        +YVAD   H+I V++  T  N T L        V + S   S+    G +
Sbjct: 479 GVTWDKKRNLLYVADSYNHKIKVVDPKTK-NCTTLAGTGDTNNVTSSSFTESTFNEPGGL 537

Query: 268 WVGCHPNGQKLFVYDPNNPPSSEVLRIQNILSEKPTVTTVYANNGSVLQG 317
            +G   NG+ L+V D NN      +++ ++ ++  +V  ++ +  +V+ G
Sbjct: 538 CIG--ENGELLYVADTNN----HQIKVMDLETKMVSVLPIFRSENAVVDG 581


>gi|157502171 sorting nexin 19 [Homo sapiens]
          Length = 992

 Score = 30.4 bits (67), Expect = 2.4
 Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 4/93 (4%)

Query: 208 DSANGINISPDDKYIYVADILAHEIHVLEKHTNMNLTQLKVLELDTLVDNLSIDPSSGDI 267
           +S   I+I   DK I   D+ A    +LE       ++   LE D   D  S+DP+   +
Sbjct: 442 NSCPEIHIDTADKEIEQGDVTASVTALLEGPEKTCPSRPSCLEKDLTNDVSSLDPTLPPV 501

Query: 268 WVGCHPNG---QKLFVYDPNNPPSSEVLRIQNI 297
            +   P G      F ++P + P   V+ IQN+
Sbjct: 502 LLSSSPPGPLSSATFSFEPLSSPDGPVI-IQNL 533


>gi|23510338 ubiquitin-activating enzyme E1 [Homo sapiens]
          Length = 1058

 Score = 29.3 bits (64), Expect = 5.3
 Identities = 24/67 (35%), Positives = 31/67 (46%), Gaps = 11/67 (16%)

Query: 273 PNGQKLFVYDPNNPPSSEVLRIQNILSEKPTVTTVYANNGSVLQGSSVASVYDGKLLIGT 332
           P  +K  V  P+  P S     Q++LSE P+V T    NG    GS  A + +G      
Sbjct: 5   PLSKKRRVSGPDPKPGSNCSPAQSVLSEVPSVPT----NGMAKNGSE-ADIDEG------ 53

Query: 333 LYHRALY 339
           LY R LY
Sbjct: 54  LYSRQLY 60


>gi|23510340 ubiquitin-activating enzyme E1 [Homo sapiens]
          Length = 1058

 Score = 29.3 bits (64), Expect = 5.3
 Identities = 24/67 (35%), Positives = 31/67 (46%), Gaps = 11/67 (16%)

Query: 273 PNGQKLFVYDPNNPPSSEVLRIQNILSEKPTVTTVYANNGSVLQGSSVASVYDGKLLIGT 332
           P  +K  V  P+  P S     Q++LSE P+V T    NG    GS  A + +G      
Sbjct: 5   PLSKKRRVSGPDPKPGSNCSPAQSVLSEVPSVPT----NGMAKNGSE-ADIDEG------ 53

Query: 333 LYHRALY 339
           LY R LY
Sbjct: 54  LYSRQLY 60


>gi|4826724 zygin 1 isoform 1 [Homo sapiens]
          Length = 392

 Score = 28.9 bits (63), Expect = 7.0
 Identities = 15/48 (31%), Positives = 23/48 (47%)

Query: 137 ENSLLHLKTVKHELLPSVNDITAVGPAHFYATNDHYFSDPFLKYLETY 184
           E  L+ L     +L PS ++     P  FY ++ H+  DP L  LE +
Sbjct: 2   EAPLVSLDEEFEDLRPSCSEDPEEKPQCFYGSSPHHLEDPSLSELENF 49


>gi|12025680 zygin 1 isoform 2 [Homo sapiens]
          Length = 104

 Score = 28.9 bits (63), Expect = 7.0
 Identities = 15/48 (31%), Positives = 23/48 (47%)

Query: 137 ENSLLHLKTVKHELLPSVNDITAVGPAHFYATNDHYFSDPFLKYLETY 184
           E  L+ L     +L PS ++     P  FY ++ H+  DP L  LE +
Sbjct: 2   EAPLVSLDEEFEDLRPSCSEDPEEKPQCFYGSSPHHLEDPSLSELENF 49


>gi|226442779 jumonji domain containing 1A [Homo sapiens]
          Length = 1321

 Score = 28.9 bits (63), Expect = 7.0
 Identities = 18/50 (36%), Positives = 26/50 (52%), Gaps = 4/50 (8%)

Query: 271 CHPNGQKLFVYDPNNPPSSEVLRIQNILSEKPTVTTVYANNGSVLQGSSV 320
           C     KLF    + P S E L+  ++  EKPT+  V   N SVL+ ++V
Sbjct: 753 CSNRQFKLF----SKPASKEDLKQTSLAGEKPTLGAVLQQNPSVLEPAAV 798


>gi|20357522 jumonji domain containing 1A [Homo sapiens]
          Length = 1321

 Score = 28.9 bits (63), Expect = 7.0
 Identities = 18/50 (36%), Positives = 26/50 (52%), Gaps = 4/50 (8%)

Query: 271 CHPNGQKLFVYDPNNPPSSEVLRIQNILSEKPTVTTVYANNGSVLQGSSV 320
           C     KLF    + P S E L+  ++  EKPT+  V   N SVL+ ++V
Sbjct: 753 CSNRQFKLF----SKPASKEDLKQTSLAGEKPTLGAVLQQNPSVLEPAAV 798


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.138    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,957,757
Number of Sequences: 37866
Number of extensions: 577181
Number of successful extensions: 1197
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1183
Number of HSP's gapped (non-prelim): 16
length of query: 342
length of database: 18,247,518
effective HSP length: 103
effective length of query: 239
effective length of database: 14,347,320
effective search space: 3429009480
effective search space used: 3429009480
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.