Search of human proteins with 63253298

Search of human proteins with 63253298

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|63253298 spermidine synthase [Homo sapiens]
         (302 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|63253298 spermidine synthase [Homo sapiens]                        621   e-178
gi|21264341 spermine synthase [Homo sapiens]                           69   5e-12
gi|42542403 CGI-01 protein isoform 1 [Homo sapiens]                    47   2e-05
gi|42542405 CGI-01 protein isoform 2 [Homo sapiens]                    47   2e-05
gi|55956895 CGI-01 protein isoform 3 [Homo sapiens]                    47   2e-05
gi|156564367 hypothetical protein LOC113802 [Homo sapiens]             31   1.5  
gi|156564365 hypothetical protein LOC113802 [Homo sapiens]             31   1.5  
gi|155030240 tRNA nucleotidyl transferase, CCA-adding, 1 [Homo s...    29   5.8  
gi|199559490 Abelson helper integration site 1 isoform a [Homo s...    29   5.8  
gi|199559438 Abelson helper integration site 1 isoform a [Homo s...    29   5.8  
gi|31542701 Abelson helper integration site 1 isoform a [Homo sa...    29   5.8  
gi|124256474 diacylglycerol kinase gamma isoform 2 [Homo sapiens]      29   5.8  
gi|21687139 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltran...    28   7.6  
gi|124256482 diacylglycerol kinase gamma isoform 3 [Homo sapiens]      28   7.6  
gi|124256476 diacylglycerol kinase gamma isoform 1 [Homo sapiens]      28   7.6  
gi|4506525 rhomboid protease 1 [Homo sapiens]                          28   10.0 

>gi|63253298 spermidine synthase [Homo sapiens]
          Length = 302

 Score =  621 bits (1602), Expect = e-178
 Identities = 302/302 (100%), Positives = 302/302 (100%)

Query: 1   MEPGPDGPAASGPAAIREGWFRETCSLWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYG 60
           MEPGPDGPAASGPAAIREGWFRETCSLWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYG
Sbjct: 1   MEPGPDGPAASGPAAIREGWFRETCSLWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYG 60

Query: 61  NVLVLDGVIQCTERDEFSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESV 120
           NVLVLDGVIQCTERDEFSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESV
Sbjct: 61  NVLVLDGVIQCTERDEFSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESV 120

Query: 121 VQCEIDEDVIQVSKKFLPGMAIGYSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGP 180
           VQCEIDEDVIQVSKKFLPGMAIGYSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGP
Sbjct: 121 VQCEIDEDVIQVSKKFLPGMAIGYSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGP 180

Query: 181 AESLFKESYYQLMKTALKEDGVLCCQGECQWLHLDLIKEMRQFCQSLFPVVAYAYCTIPT 240
           AESLFKESYYQLMKTALKEDGVLCCQGECQWLHLDLIKEMRQFCQSLFPVVAYAYCTIPT
Sbjct: 181 AESLFKESYYQLMKTALKEDGVLCCQGECQWLHLDLIKEMRQFCQSLFPVVAYAYCTIPT 240

Query: 241 YPSGQIGFMLCSKNPSTNFQEPVQPLTQQQVAQMQLKYYNSDVHRAAFVLPEFARKALND 300
           YPSGQIGFMLCSKNPSTNFQEPVQPLTQQQVAQMQLKYYNSDVHRAAFVLPEFARKALND
Sbjct: 241 YPSGQIGFMLCSKNPSTNFQEPVQPLTQQQVAQMQLKYYNSDVHRAAFVLPEFARKALND 300

Query: 301 VS 302
           VS
Sbjct: 301 VS 302


>gi|21264341 spermine synthase [Homo sapiens]
          Length = 366

 Score = 68.9 bits (167), Expect = 5e-12
 Identities = 58/203 (28%), Positives = 92/203 (45%), Gaps = 29/203 (14%)

Query: 28  WP---GQALSLQVEQLLHHRRSRYQDILVFRSKTYGNVLVLDGVIQCTERDEFSYQEMIA 84
           WP   G+ +   ++++++   S YQ+I +  SK +GN+L+L G +   E D  +Y   I 
Sbjct: 124 WPTADGRLVEYDIDEVVYDEDSPYQNIKILHSKQFGNILILSGDVNLAESD-LAYTRAIM 182

Query: 85  NLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMAIGY 144
                 +   + VLI+GGGDGG+L E+VK    + V   EID+ VI   KK++       
Sbjct: 183 GSGKEDYTG-KDVLILGGGDGGILCEIVK-LKPKMVTMVEIDQMVIDGCKKYMRKTC--- 237

Query: 145 SSSKLTLHVGDGFE------------FMKQNQDAFDVIITD------SSDPMGPAESLFK 186
               L    GD ++            + K+ ++ FD +I D      S+ P   +   F 
Sbjct: 238 -GDVLDNLKGDCYQVLIEDCIPVLKRYAKEGRE-FDYVINDLTAVPISTSPEEDSTWEFL 295

Query: 187 ESYYQLMKTALKEDGVLCCQGEC 209
                L    LK+DG    QG C
Sbjct: 296 RLILDLSMKVLKQDGKYFTQGNC 318


>gi|42542403 CGI-01 protein isoform 1 [Homo sapiens]
          Length = 699

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 41/154 (26%), Positives = 76/154 (49%), Gaps = 23/154 (14%)

Query: 79  YQEMIANLPLCSHPN-----PRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVS 133
           ++ MIA L L  +P      P  +L++G G G +   V  H     +   EID  +++V+
Sbjct: 474 HKAMIAGLALLRNPELLLEIPLALLVVGLGGGSLPLFVHDHFPKSCIDAVEIDPSMLEVA 533

Query: 134 KKFLPGMAIGYS-SSKLTLHVGDGFEFMK------QNQDAFDVII--TDSSDP-MG---P 180
            ++      G+S S ++ +H+ DG +++       + +  +DVI+   DS DP +G   P
Sbjct: 534 TQW-----FGFSQSDRMKVHIADGLDYIASLAGGGEARPCYDVIMFDVDSKDPTLGMSCP 588

Query: 181 AESLFKESYYQLMKTALKEDGVLCCQGECQWLHL 214
             +  ++S+ Q +K+ L  +GV      C+ L L
Sbjct: 589 PPAFVEQSFLQKVKSILTPEGVFILNLVCRDLGL 622


>gi|42542405 CGI-01 protein isoform 2 [Homo sapiens]
          Length = 613

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 41/154 (26%), Positives = 76/154 (49%), Gaps = 23/154 (14%)

Query: 79  YQEMIANLPLCSHPN-----PRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVS 133
           ++ MIA L L  +P      P  +L++G G G +   V  H     +   EID  +++V+
Sbjct: 388 HKAMIAGLALLRNPELLLEIPLALLVVGLGGGSLPLFVHDHFPKSCIDAVEIDPSMLEVA 447

Query: 134 KKFLPGMAIGYS-SSKLTLHVGDGFEFMK------QNQDAFDVII--TDSSDP-MG---P 180
            ++      G+S S ++ +H+ DG +++       + +  +DVI+   DS DP +G   P
Sbjct: 448 TQW-----FGFSQSDRMKVHIADGLDYIASLAGGGEARPCYDVIMFDVDSKDPTLGMSCP 502

Query: 181 AESLFKESYYQLMKTALKEDGVLCCQGECQWLHL 214
             +  ++S+ Q +K+ L  +GV      C+ L L
Sbjct: 503 PPAFVEQSFLQKVKSILTPEGVFILNLVCRDLGL 536


>gi|55956895 CGI-01 protein isoform 3 [Homo sapiens]
          Length = 543

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 41/154 (26%), Positives = 76/154 (49%), Gaps = 23/154 (14%)

Query: 79  YQEMIANLPLCSHPN-----PRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVS 133
           ++ MIA L L  +P      P  +L++G G G +   V  H     +   EID  +++V+
Sbjct: 318 HKAMIAGLALLRNPELLLEIPLALLVVGLGGGSLPLFVHDHFPKSCIDAVEIDPSMLEVA 377

Query: 134 KKFLPGMAIGYS-SSKLTLHVGDGFEFMK------QNQDAFDVII--TDSSDP-MG---P 180
            ++      G+S S ++ +H+ DG +++       + +  +DVI+   DS DP +G   P
Sbjct: 378 TQW-----FGFSQSDRMKVHIADGLDYIASLAGGGEARPCYDVIMFDVDSKDPTLGMSCP 432

Query: 181 AESLFKESYYQLMKTALKEDGVLCCQGECQWLHL 214
             +  ++S+ Q +K+ L  +GV      C+ L L
Sbjct: 433 PPAFVEQSFLQKVKSILTPEGVFILNLVCRDLGL 466


>gi|156564367 hypothetical protein LOC113802 [Homo sapiens]
          Length = 393

 Score = 30.8 bits (68), Expect = 1.5
 Identities = 15/44 (34%), Positives = 26/44 (59%)

Query: 88  LCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQ 131
           L     P+KV  +G GD  +LR +  +P +E +V  +I+ED ++
Sbjct: 42  LVDQHEPKKVADLGCGDTSLLRLLKVNPCIELLVGVDINEDKLR 85


>gi|156564365 hypothetical protein LOC113802 [Homo sapiens]
          Length = 393

 Score = 30.8 bits (68), Expect = 1.5
 Identities = 15/44 (34%), Positives = 26/44 (59%)

Query: 88  LCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQ 131
           L     P+KV  +G GD  +LR +  +P +E +V  +I+ED ++
Sbjct: 42  LVDQHEPKKVADLGCGDTSLLRLLKVNPCIELLVGVDINEDKLR 85


>gi|155030240 tRNA nucleotidyl transferase, CCA-adding, 1 [Homo
           sapiens]
          Length = 434

 Score = 28.9 bits (63), Expect = 5.8
 Identities = 29/96 (30%), Positives = 43/96 (44%), Gaps = 11/96 (11%)

Query: 156 GFEFMKQNQDAFDVIITDSSDPMGPAESLFKESYYQLMKTALKEDGVLCCQGE-CQWLHL 214
           G   +K  +D      TDSSDP+ P +    +S      T + E  +L  QGE C     
Sbjct: 323 GLFIVKNRKDLIKA--TDSSDPLKPYQDFIIDSREPDATTRVCE--LLKYQGEHC----- 373

Query: 215 DLIKEMRQFCQSLFPVVAYAYCTIPTYPSGQIGFML 250
            L+KEM+Q+    FPV  +    +      +IG +L
Sbjct: 374 -LLKEMQQWSIPPFPVSGHDIRKVGISSGKEIGALL 408


>gi|199559490 Abelson helper integration site 1 isoform a [Homo
            sapiens]
          Length = 1196

 Score = 28.9 bits (63), Expect = 5.8
 Identities = 18/55 (32%), Positives = 27/55 (49%), Gaps = 1/55 (1%)

Query: 146  SSKLTLHVGDGFE-FMKQNQDAFDVIITDSSDPMGPAESLFKESYYQLMKTALKE 199
            S +LT+H GD    F K N+D +   I    +   PA  +  E+ YQ +   +KE
Sbjct: 1067 SDELTIHRGDIIRVFFKDNEDWWYGSIGKGQEGYFPANHVASETLYQELPPEIKE 1121


>gi|199559438 Abelson helper integration site 1 isoform a [Homo
            sapiens]
          Length = 1196

 Score = 28.9 bits (63), Expect = 5.8
 Identities = 18/55 (32%), Positives = 27/55 (49%), Gaps = 1/55 (1%)

Query: 146  SSKLTLHVGDGFE-FMKQNQDAFDVIITDSSDPMGPAESLFKESYYQLMKTALKE 199
            S +LT+H GD    F K N+D +   I    +   PA  +  E+ YQ +   +KE
Sbjct: 1067 SDELTIHRGDIIRVFFKDNEDWWYGSIGKGQEGYFPANHVASETLYQELPPEIKE 1121


>gi|31542701 Abelson helper integration site 1 isoform a [Homo
            sapiens]
          Length = 1196

 Score = 28.9 bits (63), Expect = 5.8
 Identities = 18/55 (32%), Positives = 27/55 (49%), Gaps = 1/55 (1%)

Query: 146  SSKLTLHVGDGFE-FMKQNQDAFDVIITDSSDPMGPAESLFKESYYQLMKTALKE 199
            S +LT+H GD    F K N+D +   I    +   PA  +  E+ YQ +   +KE
Sbjct: 1067 SDELTIHRGDIIRVFFKDNEDWWYGSIGKGQEGYFPANHVASETLYQELPPEIKE 1121


>gi|124256474 diacylglycerol kinase gamma isoform 2 [Homo sapiens]
          Length = 766

 Score = 28.9 bits (63), Expect = 5.8
 Identities = 19/71 (26%), Positives = 36/71 (50%), Gaps = 1/71 (1%)

Query: 44  RRSRYQDILVFRSKTYGNVLVLDGVIQCTERDEFSYQEMIANLPLCSHPNPRKVLIIGGG 103
           R + ++D   FR    G    +  ++ C ++  F+    +A LPL +  +  + L  GGG
Sbjct: 450 RLNFFRDTPDFRVLACGGDGTVGWILDCIDKANFAKHPPVAVLPLGTGNDLARCLRWGGG 509

Query: 104 -DGGVLREVVK 113
            +GG L +++K
Sbjct: 510 YEGGSLTKILK 520


>gi|21687139 UDP-GlcNAc:betaGal
           beta-1,3-N-acetylglucosaminyltransferase 7 [Homo
           sapiens]
          Length = 401

 Score = 28.5 bits (62), Expect = 7.6
 Identities = 17/53 (32%), Positives = 25/53 (47%), Gaps = 4/53 (7%)

Query: 15  AIREGWFRETCSLWPGQA----LSLQVEQLLHHRRSRYQDILVFRSKTYGNVL 63
           AIR+ W RE  S   G+     L L         R+ YQ +L +  + YG++L
Sbjct: 152 AIRQTWGRERQSAGGGRGAVRTLFLLGTASKQEERTHYQQLLAYEDRLYGDIL 204


>gi|124256482 diacylglycerol kinase gamma isoform 3 [Homo sapiens]
          Length = 752

 Score = 28.5 bits (62), Expect = 7.6
 Identities = 18/67 (26%), Positives = 34/67 (50%), Gaps = 1/67 (1%)

Query: 48  YQDILVFRSKTYGNVLVLDGVIQCTERDEFSYQEMIANLPLCSHPNPRKVLIIGGG-DGG 106
           ++D   FR    G    +  ++ C ++  F+    +A LPL +  +  + L  GGG +GG
Sbjct: 440 FRDTPDFRVLACGGDGTVGWILDCIDKANFAKHPPVAVLPLGTGNDLARCLRWGGGYEGG 499

Query: 107 VLREVVK 113
            L +++K
Sbjct: 500 SLTKILK 506


>gi|124256476 diacylglycerol kinase gamma isoform 1 [Homo sapiens]
          Length = 791

 Score = 28.5 bits (62), Expect = 7.6
 Identities = 18/67 (26%), Positives = 34/67 (50%), Gaps = 1/67 (1%)

Query: 48  YQDILVFRSKTYGNVLVLDGVIQCTERDEFSYQEMIANLPLCSHPNPRKVLIIGGG-DGG 106
           ++D   FR    G    +  ++ C ++  F+    +A LPL +  +  + L  GGG +GG
Sbjct: 479 FRDTPDFRVLACGGDGTVGWILDCIDKANFAKHPPVAVLPLGTGNDLARCLRWGGGYEGG 538

Query: 107 VLREVVK 113
            L +++K
Sbjct: 539 SLTKILK 545


>gi|4506525 rhomboid protease 1 [Homo sapiens]
          Length = 438

 Score = 28.1 bits (61), Expect = 10.0
 Identities = 38/145 (26%), Positives = 59/145 (40%), Gaps = 28/145 (19%)

Query: 2   EPGPDGPAASGPAAIREGWFRETCSLWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYGN 61
           EP PD P+  GPA    G  R T +L  G +L     Q L    + +     F    + +
Sbjct: 47  EPEPDAPSQPGPALWSRGRAR-TQALAGGSSL-----QQLDPENTGFIGADTFTGLVHSH 100

Query: 62  VLVLD--------GVIQCTERDEFSYQEMIANLPLCSHPNPRKVLIIGG-----GDG--- 105
            L LD         + Q  E+ +  YQE++ +L      +  K  I  G      DG   
Sbjct: 101 ELPLDPAKLDMLVALAQSNEQGQVCYQELV-DLISSKRSSSFKRAIANGQRALPRDGPLD 159

Query: 106 ----GVLREVVKHPSVESVVQCEID 126
               GV +  V++ + E ++ CE+D
Sbjct: 160 EPGLGVYKRFVRYVAYE-ILPCEVD 183


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.137    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,569,276
Number of Sequences: 37866
Number of extensions: 570686
Number of successful extensions: 1293
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 1286
Number of HSP's gapped (non-prelim): 16
length of query: 302
length of database: 18,247,518
effective HSP length: 102
effective length of query: 200
effective length of database: 14,385,186
effective search space: 2877037200
effective search space used: 2877037200
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.