Guide to the Human Genome
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Search of human proteins with 63079718

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|63079718 three prime repair exonuclease 2 [Homo sapiens]
         (236 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|63079718 three prime repair exonuclease 2 [Homo sapiens]           479   e-135
gi|18375535 three prime repair exonuclease 1 isoform b [Homo sap...   177   9e-45
gi|7705353 three prime repair exonuclease 1 isoform a [Homo sapi...   177   9e-45
gi|71774197 ubiquitin specific protease 47 [Homo sapiens]              34   0.13 
gi|11968009 SIL1 protein precursor [Homo sapiens]                      33   0.28 
gi|83641896 SIL1 protein precursor [Homo sapiens]                      33   0.28 
gi|168229174 RNA binding motif protein 27 [Homo sapiens]               30   2.4  
gi|53729334 membrane-associated ring finger (C3HC4) 2 isoform 2 ...    29   4.0  
gi|53729332 membrane-associated ring finger (C3HC4) 2 isoform 1 ...    29   4.0  
gi|53729330 membrane-associated ring finger (C3HC4) 2 isoform 1 ...    29   4.0  

>gi|63079718 three prime repair exonuclease 2 [Homo sapiens]
          Length = 236

 Score =  479 bits (1232), Expect = e-135
 Identities = 236/236 (100%), Positives = 236/236 (100%)

Query: 1   MSEAPRAETFVFLDLEATGLPSVEPEIAELSLFAVHRSSLENPEHDESGALVLPRVLDKL 60
           MSEAPRAETFVFLDLEATGLPSVEPEIAELSLFAVHRSSLENPEHDESGALVLPRVLDKL
Sbjct: 1   MSEAPRAETFVFLDLEATGLPSVEPEIAELSLFAVHRSSLENPEHDESGALVLPRVLDKL 60

Query: 61  TLCMCPERPFTAKASEITGLSSEGLARCRKAGFDGAVVRTLQAFLSRQAGPICLVAHNGF 120
           TLCMCPERPFTAKASEITGLSSEGLARCRKAGFDGAVVRTLQAFLSRQAGPICLVAHNGF
Sbjct: 61  TLCMCPERPFTAKASEITGLSSEGLARCRKAGFDGAVVRTLQAFLSRQAGPICLVAHNGF 120

Query: 121 DYDFPLLCAELRRLGARLPRDTVCLDTLPALRGLDRAHSHGTRARGRQGYSLGSLFHRYF 180
           DYDFPLLCAELRRLGARLPRDTVCLDTLPALRGLDRAHSHGTRARGRQGYSLGSLFHRYF
Sbjct: 121 DYDFPLLCAELRRLGARLPRDTVCLDTLPALRGLDRAHSHGTRARGRQGYSLGSLFHRYF 180

Query: 181 RAEPSAAHSAEGDVHTLLLIFLHRAAELLAWADEQARGWAHIEPMYLPPDDPSLEA 236
           RAEPSAAHSAEGDVHTLLLIFLHRAAELLAWADEQARGWAHIEPMYLPPDDPSLEA
Sbjct: 181 RAEPSAAHSAEGDVHTLLLIFLHRAAELLAWADEQARGWAHIEPMYLPPDDPSLEA 236


>gi|18375535 three prime repair exonuclease 1 isoform b [Homo
           sapiens]
          Length = 314

 Score =  177 bits (448), Expect = 9e-45
 Identities = 105/226 (46%), Positives = 135/226 (59%), Gaps = 11/226 (4%)

Query: 8   ETFVFLDLEATGLPSVEPEIAELSLFAVHRSSLENPEHDESGALVLP---RVLDKLTLCM 64
           +T +F D+EATGLP  +P++ EL L AVHR +LE+P   +     +P   RV+DKL+LC+
Sbjct: 12  QTLIFFDMEATGLPFSQPKVTELCLLAVHRCALESPPTSQGPPPTVPPPPRVVDKLSLCV 71

Query: 65  CPERPFTAKASEITGLSSEGLARCRKAGFDGAVVRTLQAFLSRQAGPICLVAHNGFDYDF 124
            P +  +  ASEITGLS+  LA   +  FD  +   L AFL RQ  P CLVAHNG  YDF
Sbjct: 72  APGKACSPAASEITGLSTAVLAAHGRQCFDDNLANLLLAFLRRQPQPWCLVAHNGDRYDF 131

Query: 125 PLLCAELRRLGARLPRD-TVCLDTLPALRGLDRAHS---HGTRARGRQGYSLGSLFHRYF 180
           PLL AEL  LG     D   C+D++ AL+ L+RA S   HG     R+ YSLGS++ R +
Sbjct: 132 PLLQAELAMLGLTSALDGAFCVDSITALKALERASSPSEHGP----RKSYSLGSIYTRLY 187

Query: 181 RAEPSAAHSAEGDVHTLLLIFLHRAAELLAWADEQARGWAHIEPMY 226
              P  +H+AEGDV  LL I   R   LL W D  AR +  I PMY
Sbjct: 188 GQSPPDSHTAEGDVLALLSICQWRPQALLRWVDAHARPFGTIRPMY 233


>gi|7705353 three prime repair exonuclease 1 isoform a [Homo
           sapiens]
          Length = 369

 Score =  177 bits (448), Expect = 9e-45
 Identities = 105/226 (46%), Positives = 135/226 (59%), Gaps = 11/226 (4%)

Query: 8   ETFVFLDLEATGLPSVEPEIAELSLFAVHRSSLENPEHDESGALVLP---RVLDKLTLCM 64
           +T +F D+EATGLP  +P++ EL L AVHR +LE+P   +     +P   RV+DKL+LC+
Sbjct: 67  QTLIFFDMEATGLPFSQPKVTELCLLAVHRCALESPPTSQGPPPTVPPPPRVVDKLSLCV 126

Query: 65  CPERPFTAKASEITGLSSEGLARCRKAGFDGAVVRTLQAFLSRQAGPICLVAHNGFDYDF 124
            P +  +  ASEITGLS+  LA   +  FD  +   L AFL RQ  P CLVAHNG  YDF
Sbjct: 127 APGKACSPAASEITGLSTAVLAAHGRQCFDDNLANLLLAFLRRQPQPWCLVAHNGDRYDF 186

Query: 125 PLLCAELRRLGARLPRD-TVCLDTLPALRGLDRAHS---HGTRARGRQGYSLGSLFHRYF 180
           PLL AEL  LG     D   C+D++ AL+ L+RA S   HG     R+ YSLGS++ R +
Sbjct: 187 PLLQAELAMLGLTSALDGAFCVDSITALKALERASSPSEHGP----RKSYSLGSIYTRLY 242

Query: 181 RAEPSAAHSAEGDVHTLLLIFLHRAAELLAWADEQARGWAHIEPMY 226
              P  +H+AEGDV  LL I   R   LL W D  AR +  I PMY
Sbjct: 243 GQSPPDSHTAEGDVLALLSICQWRPQALLRWVDAHARPFGTIRPMY 288


>gi|71774197 ubiquitin specific protease 47 [Homo sapiens]
          Length = 1287

 Score = 33.9 bits (76), Expect = 0.13
 Identities = 18/56 (32%), Positives = 28/56 (50%), Gaps = 7/56 (12%)

Query: 169 GYSLGSLFHRYFRAEPSAAHSAEGDVHTLLLIFLHRAAELLAWADEQARGWAHIEP 224
           G S G + + YF+AEP AA    G+ H  L++ + +   L A+         H+EP
Sbjct: 935 GKSRGEMQYMYFKAEPYAADEGSGEGHKWLMVHVDKRITLAAFKQ-------HLEP 983


>gi|11968009 SIL1 protein precursor [Homo sapiens]
          Length = 461

 Score = 32.7 bits (73), Expect = 0.28
 Identities = 27/86 (31%), Positives = 37/86 (43%), Gaps = 10/86 (11%)

Query: 1   MSEAPRAETFVFLDLEATGLPSVEPEIAELSLFAVHRSSLENP----EHDESGALVLPRV 56
           M  A    +F  L +   GL S EP + E + F +  +   NP    E  E GA      
Sbjct: 216 MDNAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVLGAAFSSNPKVQVEAIEGGA------ 269

Query: 57  LDKLTLCMCPERPFTAKASEITGLSS 82
           L KL + +  E+P TAK   +  L S
Sbjct: 270 LQKLLVILATEQPLTAKKKVLFALCS 295


>gi|83641896 SIL1 protein precursor [Homo sapiens]
          Length = 461

 Score = 32.7 bits (73), Expect = 0.28
 Identities = 27/86 (31%), Positives = 37/86 (43%), Gaps = 10/86 (11%)

Query: 1   MSEAPRAETFVFLDLEATGLPSVEPEIAELSLFAVHRSSLENP----EHDESGALVLPRV 56
           M  A    +F  L +   GL S EP + E + F +  +   NP    E  E GA      
Sbjct: 216 MDNAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVLGAAFSSNPKVQVEAIEGGA------ 269

Query: 57  LDKLTLCMCPERPFTAKASEITGLSS 82
           L KL + +  E+P TAK   +  L S
Sbjct: 270 LQKLLVILATEQPLTAKKKVLFALCS 295


>gi|168229174 RNA binding motif protein 27 [Homo sapiens]
          Length = 1060

 Score = 29.6 bits (65), Expect = 2.4
 Identities = 20/57 (35%), Positives = 25/57 (43%)

Query: 130 ELRRLGARLPRDTVCLDTLPALRGLDRAHSHGTRARGRQGYSLGSLFHRYFRAEPSA 186
           ELR+  ++L  +   L  LP  RG   +     R RGR G   GSL H      P A
Sbjct: 921 ELRKKLSQLQVEAARLGILPVGRGKTMSSQGRGRGRGRGGRGRGSLNHMVVDHRPKA 977


>gi|53729334 membrane-associated ring finger (C3HC4) 2 isoform 2
           [Homo sapiens]
          Length = 176

 Score = 28.9 bits (63), Expect = 4.0
 Identities = 18/60 (30%), Positives = 27/60 (45%), Gaps = 2/60 (3%)

Query: 61  TLCMCPERPFTAKASEITGLSSEGLARCRKAGFDGAVVRT-LQAFLSRQAGPICLVAHNG 119
           +LC C   P  +K  E TGL        +    DG ++ T ++A  +   GP C + H G
Sbjct: 12  SLCDCSGSPAFSKVVEATGLGPPQYV-AQVTSRDGRLLSTVIRALDTPSDGPFCRICHEG 70


>gi|53729332 membrane-associated ring finger (C3HC4) 2 isoform 1
           [Homo sapiens]
          Length = 246

 Score = 28.9 bits (63), Expect = 4.0
 Identities = 18/60 (30%), Positives = 27/60 (45%), Gaps = 2/60 (3%)

Query: 61  TLCMCPERPFTAKASEITGLSSEGLARCRKAGFDGAVVRT-LQAFLSRQAGPICLVAHNG 119
           +LC C   P  +K  E TGL        +    DG ++ T ++A  +   GP C + H G
Sbjct: 12  SLCDCSGSPAFSKVVEATGLGPPQYV-AQVTSRDGRLLSTVIRALDTPSDGPFCRICHEG 70


>gi|53729330 membrane-associated ring finger (C3HC4) 2 isoform 1
           [Homo sapiens]
          Length = 246

 Score = 28.9 bits (63), Expect = 4.0
 Identities = 18/60 (30%), Positives = 27/60 (45%), Gaps = 2/60 (3%)

Query: 61  TLCMCPERPFTAKASEITGLSSEGLARCRKAGFDGAVVRT-LQAFLSRQAGPICLVAHNG 119
           +LC C   P  +K  E TGL        +    DG ++ T ++A  +   GP C + H G
Sbjct: 12  SLCDCSGSPAFSKVVEATGLGPPQYV-AQVTSRDGRLLSTVIRALDTPSDGPFCRICHEG 70


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.420 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,374,065
Number of Sequences: 37866
Number of extensions: 396144
Number of successful extensions: 798
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 785
Number of HSP's gapped (non-prelim): 10
length of query: 236
length of database: 18,247,518
effective HSP length: 99
effective length of query: 137
effective length of database: 14,498,784
effective search space: 1986333408
effective search space used: 1986333408
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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