Guide to the Human Genome
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Search of human proteins with 62865890

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|62865890 dual specificity phosphatase 5 [Homo sapiens]
         (384 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|62865890 dual specificity phosphatase 5 [Homo sapiens]             772   0.0  
gi|4758204 dual specificity phosphatase 1 [Homo sapiens]              294   1e-79
gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens]    286   3e-77
gi|4758206 dual specificity phosphatase 2 [Homo sapiens]              252   3e-67
gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens]   226   3e-59
gi|238231453 dual specificity phosphatase 7 [Homo sapiens]            173   3e-43
gi|4503421 dual specificity phosphatase 9 [Homo sapiens]              157   1e-38
gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens]   156   3e-38
gi|153281158 dual specificity phosphatase 8 [Homo sapiens]            134   1e-31
gi|38372911 dual specificity phosphatase 16 [Homo sapiens]            131   9e-31
gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]   131   9e-31
gi|239047414 slingshot 1 isoform 1 [Homo sapiens]                     101   1e-21
gi|239047498 slingshot 1 isoform 3 [Homo sapiens]                     101   1e-21
gi|239047441 slingshot 1 isoform 2 [Homo sapiens]                     101   1e-21
gi|37674210 slingshot 2 [Homo sapiens]                                 99   6e-21
gi|5902002 dual specificity phosphatase 14 [Homo sapiens]              97   3e-20
gi|21536333 dual specificity phosphatase 10 isoform b [Homo sapi...    94   2e-19
gi|21536331 dual specificity phosphatase 10 isoform b [Homo sapi...    94   2e-19
gi|29826315 dual specificity phosphatase 15 isoform a [Homo sapi...    91   2e-18
gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo sapi...    91   2e-18
gi|239582767 slingshot homolog 3 [Homo sapiens]                        89   5e-18
gi|51093845 dual specificity phosphatase 18 [Homo sapiens]             89   5e-18
gi|13128968 dual specificity phosphatase 26 [Homo sapiens]             89   9e-18
gi|9910432 dual specificity phosphatase 22 [Homo sapiens]              88   1e-17
gi|75750526 dual specificity phosphatase 28 [Homo sapiens]             87   2e-17
gi|225703077 dual specificity phosphatase 21 [Homo sapiens]            86   7e-17
gi|4758208 dual specificity phosphatase 3 [Homo sapiens]               85   1e-16
gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo ...    80   4e-15
gi|194733759 serine/threonine/tyrosine interacting protein [Homo...    80   4e-15
gi|21687043 serine/threonine/tyrosine interacting protein [Homo ...    80   4e-15

>gi|62865890 dual specificity phosphatase 5 [Homo sapiens]
          Length = 384

 Score =  772 bits (1994), Expect = 0.0
 Identities = 384/384 (100%), Positives = 384/384 (100%)

Query: 1   MKVTSLDGRQLRKMLRKEAAARCVVLDCRPYLAFAASNVRGSLNVNLNSVVLRRARGGAV 60
           MKVTSLDGRQLRKMLRKEAAARCVVLDCRPYLAFAASNVRGSLNVNLNSVVLRRARGGAV
Sbjct: 1   MKVTSLDGRQLRKMLRKEAAARCVVLDCRPYLAFAASNVRGSLNVNLNSVVLRRARGGAV 60

Query: 61  SARYVLPDEAARARLLQEGGGGVAAVVVLDQGSRHWQKLREESAARVVLTSLLACLPAGP 120
           SARYVLPDEAARARLLQEGGGGVAAVVVLDQGSRHWQKLREESAARVVLTSLLACLPAGP
Sbjct: 61  SARYVLPDEAARARLLQEGGGGVAAVVVLDQGSRHWQKLREESAARVVLTSLLACLPAGP 120

Query: 121 RVYFLKGGYETFYSEYPECCVDVKPISQEKIESERALISQCGKPVVNVSYRPAYDQGGPV 180
           RVYFLKGGYETFYSEYPECCVDVKPISQEKIESERALISQCGKPVVNVSYRPAYDQGGPV
Sbjct: 121 RVYFLKGGYETFYSEYPECCVDVKPISQEKIESERALISQCGKPVVNVSYRPAYDQGGPV 180

Query: 181 EILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACATHLHYKWIPVEDSHTADISS 240
           EILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACATHLHYKWIPVEDSHTADISS
Sbjct: 181 EILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACATHLHYKWIPVEDSHTADISS 240

Query: 241 HFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRSMV 300
           HFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRSMV
Sbjct: 241 HFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRSMV 300

Query: 301 SPNFGFMGQLLQYESEILPSTPNPQPPSCQGEAAGSSLIGHLQTLSPDMQGAYCTFPASV 360
           SPNFGFMGQLLQYESEILPSTPNPQPPSCQGEAAGSSLIGHLQTLSPDMQGAYCTFPASV
Sbjct: 301 SPNFGFMGQLLQYESEILPSTPNPQPPSCQGEAAGSSLIGHLQTLSPDMQGAYCTFPASV 360

Query: 361 LAPVPTHSTVSELSRSPVATATSC 384
           LAPVPTHSTVSELSRSPVATATSC
Sbjct: 361 LAPVPTHSTVSELSRSPVATATSC 384


>gi|4758204 dual specificity phosphatase 1 [Homo sapiens]
          Length = 367

 Score =  294 bits (752), Expect = 1e-79
 Identities = 178/394 (45%), Positives = 237/394 (60%), Gaps = 39/394 (9%)

Query: 1   MKVTSLDGRQLRKMLRKEAAARCVVLDCRPYLAFAASNVRGSLNVNLNSVVLRRARGGAV 60
           M+V +LD   LR +L  E AA+C++LDCR + AF A ++ GS+NV  +++V RRA+G A+
Sbjct: 3   MEVGTLDAGGLRALLG-ERAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRAKG-AM 60

Query: 61  SARYVLPDEAARARLLQEGGGGVAAVVVLDQGSRHWQKLREESAARVVLTSLLACLPA-G 119
              +++P+   R RLL    G   AVV+LD+ S      + +    +   +L  C  A  
Sbjct: 61  GLEHIVPNAELRGRLL---AGAYHAVVLLDERSAALDGAKRDGTLALAAGAL--CREARA 115

Query: 120 PRVYFLKGGYETFYSEYPECCVDVK-------PISQEKIESERALISQCGKPVVNVSYRP 172
            +V+FLKGGYE F +  PE C           P+S    +S  +  S C  P+       
Sbjct: 116 AQVFFLKGGYEAFSASCPELCSKQSTPMGLSLPLSTSVPDSAESGCSSCSTPL------- 168

Query: 173 AYDQGGPVEILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACATHLHYKWIPVED 232
            YDQGGPVEILPFLYLGSAYHAS+ + L  L ITAL+NVS         H  YK IPVED
Sbjct: 169 -YDQGGPVEILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVED 227

Query: 233 SHTADISSHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDY 292
           +H ADISS F EAIDFID ++  GG+V VHC+AGISRS TIC+AYLM+T + +L EAF++
Sbjct: 228 NHKADISSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEF 287

Query: 293 IKQRRSMVSPNFGFMGQLLQYESEILPSTPNPQPPSCQGEAAGSSLIGHLQTLSPDMQGA 352
           +KQRRS++SPNF FMGQLLQ+ES++L        P C  E AGS  +  L       +G 
Sbjct: 288 VKQRRSIISPNFSFMGQLLQFESQVL-------APHCSAE-AGSPAMAVLD------RGT 333

Query: 353 YCTFPASVLAPVPTHSTVSELS--RSPVATATSC 384
             T   +    +P HST S LS  +SP+ T+ SC
Sbjct: 334 STTTVFNFPVSIPVHSTNSALSYLQSPITTSPSC 367


>gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens]
          Length = 394

 Score =  286 bits (731), Expect = 3e-77
 Identities = 175/376 (46%), Positives = 226/376 (60%), Gaps = 32/376 (8%)

Query: 19  AAARCVVLDCRPYLAFAASNVRGSLNVNLNSVVLRRARGGAVSARYVLP-DEAARARLLQ 77
           +  +C++LDCRP+LA +A  + GS+NV  N++V RRA+G +VS   +LP +E  RARL  
Sbjct: 41  SGGKCLLLDCRPFLAHSAGYILGSVNVRCNTIVRRRAKG-SVSLEQILPAEEEVRARLRS 99

Query: 78  EGGGGVAAVVVLDQGSRHWQKLREESAARVVLTSLLACLPAGPRVYFLKGGYETFYSEYP 137
              G  +AV+V D+ S   + LRE+S   +V+ +L         +  LKGGYE F SEYP
Sbjct: 100 ---GLYSAVIVYDERSPRAESLREDSTVSLVVQALRRNAERTD-ICLLKGGYERFSSEYP 155

Query: 138 ECCVDVK-------PISQEKIESERALISQCGKPVVNVSYRPAYDQGGPVEILPFLYLGS 190
           E C   K       P+     E      S CG P+        +DQGGPVEILPFLYLGS
Sbjct: 156 EFCSKTKALAAIPPPVPPSATEPLDLGCSSCGTPL--------HDQGGPVEILPFLYLGS 207

Query: 191 AYHASKCEFLANLHITALLNVSRRTSEACATHLHYKWIPVEDSHTADISSHFQEAIDFID 250
           AYHA++ + L  L ITALLNVS         H  YK IPVED+H ADISS F EAI++ID
Sbjct: 208 AYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADISSWFMEAIEYID 267

Query: 251 CVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRSMVSPNFGFMGQL 310
            V++  G+VLVHC+AGISRS TIC+AYLM  K+ RL+EAF+++KQRRS++SPNF FMGQL
Sbjct: 268 AVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQL 327

Query: 311 LQYESEILPSTPNPQPPSCQGEAAGSSLIGHLQTLSPDMQGAYCTFPASVLAPVPTHSTV 370
           LQ+ES++L +       SC  EAA  S  G L+            F  S    V  HS  
Sbjct: 328 LQFESQVLAT-------SCAAEAASPS--GPLRERGKTPATPTSQFVFSFPVSVGVHSAP 378

Query: 371 SELS--RSPVATATSC 384
           S L    SP+ T+ SC
Sbjct: 379 SSLPYLHSPITTSPSC 394


>gi|4758206 dual specificity phosphatase 2 [Homo sapiens]
          Length = 314

 Score =  252 bits (644), Expect = 3e-67
 Identities = 146/301 (48%), Positives = 193/301 (64%), Gaps = 14/301 (4%)

Query: 20  AARCVVLDCRPYLAFAASNVRGSLNVNLNSVVLRRARGG-AVSARYVLPDEAARARLLQE 78
           A R ++LDCRP+LAF   +VR +  V  N+++ RRARG  A     +LPD A R RL++ 
Sbjct: 24  AERTLLLDCRPFLAFCRRHVRAARPVPWNALLRRRARGPPAAVLACLLPDRALRTRLVR- 82

Query: 79  GGGGVAAVVVLDQGSRHWQKLREESAARVVLTSLLACLPAGPR-VYFLKGGYETFYSEYP 137
             G +A  VVLD+GS    +LR +S A V+L +LL    AGP  VYFL+GG++ F    P
Sbjct: 83  --GELARAVVLDEGSASVAELRPDSPAHVLLAALLHETRAGPTAVYFLRGGFDGFQGCCP 140

Query: 138 ECCVDVKPISQEKIESERALISQCGKPVVNVSYRPAYDQGGPVEILPFLYLGSAYHASKC 197
           + C +             AL     K   + S  P YDQGGPVEILP+L+LGS  H+S  
Sbjct: 141 DLCSEAPA---------PALPPTGDKTSRSDSRAPVYDQGGPVEILPYLFLGSCSHSSDL 191

Query: 198 EFLANLHITALLNVSRRTSEACATHLHYKWIPVEDSHTADISSHFQEAIDFIDCVREKGG 257
           + L    ITA+LNVS            YK IPVED+   +IS+ FQEAI FID V+  GG
Sbjct: 192 QGLQACGITAVLNVSASCPNHFEGLFRYKSIPVEDNQMVEISAWFQEAIGFIDWVKNSGG 251

Query: 258 KVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRSMVSPNFGFMGQLLQYESEI 317
           +VLVHC+AGISRS TIC+AYLM++++ RL EAFD++KQRR ++SPNF FMGQLLQ+E+++
Sbjct: 252 RVLVHCQAGISRSATICLAYLMQSRRVRLDEAFDFVKQRRGVISPNFSFMGQLLQFETQV 311

Query: 318 L 318
           L
Sbjct: 312 L 312


>gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens]
          Length = 303

 Score =  226 bits (576), Expect = 3e-59
 Identities = 133/268 (49%), Positives = 162/268 (60%), Gaps = 26/268 (9%)

Query: 126 KGGYETFYSEYPECCVDVK-------PISQEKIESERALISQCGKPVVNVSYRPAYDQGG 178
           +GGYE F SEYPE C   K       P+     E      S CG P+        +DQGG
Sbjct: 53  QGGYERFSSEYPEFCSKTKALAAIPPPVPPSATEPLDLGCSSCGTPL--------HDQGG 104

Query: 179 PVEILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACATHLHYKWIPVEDSHTADI 238
           PVEILPFLYLGSAYHA++ + L  L ITALLNVS         H  YK IPVED+H ADI
Sbjct: 105 PVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADI 164

Query: 239 SSHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRS 298
           SS F EAI++ID V++  G+VLVHC+AGISRS TIC+AYLM  K+ RL+EAF+++KQRRS
Sbjct: 165 SSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRS 224

Query: 299 MVSPNFGFMGQLLQYESEILPSTPNPQPPSCQGEAAGSSLIGHLQTLSPDMQGAYCTFPA 358
           ++SPNF FMGQLLQ+ES++L +       SC  EAA  S  G L+            F  
Sbjct: 225 IISPNFSFMGQLLQFESQVLAT-------SCAAEAASPS--GPLRERGKTPATPTSQFVF 275

Query: 359 SVLAPVPTHSTVSELS--RSPVATATSC 384
           S    V  HS  S L    SP+ T+ SC
Sbjct: 276 SFPVSVGVHSAPSSLPYLHSPITTSPSC 303


>gi|238231453 dual specificity phosphatase 7 [Homo sapiens]
          Length = 419

 Score =  173 bits (438), Expect = 3e-43
 Identities = 123/357 (34%), Positives = 182/357 (50%), Gaps = 45/357 (12%)

Query: 11  LRKMLRKEAAARCVVLDCRPYLAFAASNVRGSLNVNLNSVVLRRARGGAVSARYVLPDEA 70
           L++ L     A  ++LDCRP+  F +S++  ++N+ +  ++LRR R G +  R ++P+ A
Sbjct: 60  LQEELEARGGASLLLLDCRPHELFESSHIETAINLAIPGLMLRRLRKGNLPIRSIIPNHA 119

Query: 71  ARARLLQEGGGGVAAVVVLDQGSRHWQKLREESAARVVLTSLLACL-PAGPRVYFLKGGY 129
            + R         A V++ D+ +  WQ   E  A   VL  LL  L   G + Y+L+GG+
Sbjct: 120 DKERFATRCKA--ATVLLYDEATAEWQP--EPGAPASVLGLLLQKLRDDGCQAYYLQGGF 175

Query: 130 ETFYSEYPECC---------------VDVKPISQEKI-------ESERALISQC----GK 163
             F +EY E C                 V  +   +I       ES+R L S      G 
Sbjct: 176 NKFQTEYSEHCETNVDSSSSPSSSPPTSVLGLGGLRISSDCSDGESDRELPSSATESDGS 235

Query: 164 PVVNVSYRPAYDQGGPVEILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEAC--AT 221
           PV   S +PA+    PV+ILP+LYLG A  ++  + L    I  +LNV+     A     
Sbjct: 236 PVP--SSQPAF----PVQILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGG 289

Query: 222 HLHYKWIPVEDSHTADISSHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKT 281
              YK IP+ D  + ++S  F EAI FID  R K   VLVHC AGISRS T+ +AYLM+ 
Sbjct: 290 EFTYKQIPISDHWSQNLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQK 349

Query: 282 KQFRLKEAFDYIKQRRSMVSPNFGFMGQLLQYESEILPSTPNPQPPSCQGEAAGSSL 338
               L +A+D++K+++S +SPNF FMGQLL +E  +  S+P      C   A+   L
Sbjct: 350 MNLSLNDAYDFVKRKKSNISPNFNFMGQLLDFERTLGLSSP------CDNHASSEQL 400


>gi|4503421 dual specificity phosphatase 9 [Homo sapiens]
          Length = 384

 Score =  157 bits (398), Expect = 1e-38
 Identities = 118/362 (32%), Positives = 181/362 (50%), Gaps = 47/362 (12%)

Query: 15  LRKEAAA---RCVVLDCRPYLAFAASNVRGSLNVNLNSVVLRRARGGAVSARYVLPDEAA 71
           LR+E +    R ++LDCR    + ++ + G+L+V L +++LRR R G++S R +LP    
Sbjct: 11  LRRELSPPRPRLLLLDCRSRELYESARIGGALSVALPALLLRRLRRGSLSVRALLPGPPL 70

Query: 72  RAR-----LLQEGGGGVAAVVVLDQGSRHWQKLREESAARVVLTSLLACL-PAGPRVYFL 125
           +       LL + GGG       +  +  W+       A  VL +LL  L   G   Y+L
Sbjct: 71  QPPPPAPVLLYDQGGGRRRRGEAEAEAEEWE-------AESVLGTLLQKLREEGYLAYYL 123

Query: 126 KGGYETFYSEYPECCV---------DVKPI------------------SQEKIESERALI 158
           +GG+  F +E P  C           + P+                  S  + E++R  +
Sbjct: 124 QGGFSRFQAECPHLCETSLAGRAGSSMAPVPGPVPVVGLGSLCLGSDCSDAESEADRDSM 183

Query: 159 SQCGKPVVNVSYRPAYDQGG-PVEILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSE 217
           S CG      +  P   +   PV+ILP LYLGSA  ++  E LA L I  +LNV+     
Sbjct: 184 S-CGLDSEGATPPPVGLRASFPVQILPNLYLGSARDSANLESLAKLGIRYILNVTPNLPN 242

Query: 218 ACATH--LHYKWIPVEDSHTADISSHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICM 275
               +   HYK IP+ D  + ++S  F EAI+FID    +   VLVHC AG+SRS T+ +
Sbjct: 243 FFEKNGDFHYKQIPISDHWSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTV 302

Query: 276 AYLMKTKQFRLKEAFDYIKQRRSMVSPNFGFMGQLLQYESEILPSTPNPQPPSCQGEAAG 335
           AYLM+     L +A+D +K+++S +SPNF FMGQLL +E  +     + Q     G+A+ 
Sbjct: 303 AYLMQKLHLSLNDAYDLVKRKKSNISPNFNFMGQLLDFERSLRLEERHSQEQGSGGQASA 362

Query: 336 SS 337
           +S
Sbjct: 363 AS 364


>gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens]
          Length = 381

 Score =  156 bits (394), Expect = 3e-38
 Identities = 109/331 (32%), Positives = 164/331 (49%), Gaps = 41/331 (12%)

Query: 22  RCVVLDCRPYLAFAASNVRGSLNVNLNSVVLRRARGGAVSARYVLPDEAARARLLQEGGG 81
           R +++DCRP   + +S++  ++NV +  ++LRR + G +  R +      R R  +  G 
Sbjct: 33  RLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRGEDRDRFTRRCG- 91

Query: 82  GVAAVVVLDQGSRHWQKLREESAARVVLTSLLACLP-AGPRVYFLKGGYETFYSEYPECC 140
               VV+ D+ S  W    E +    VL  LL  L   G R ++L+GG+  F +E+   C
Sbjct: 92  -TDTVVLYDESSSDWN---ENTGGESVLGLLLKKLKDEGCRAFYLEGGFSKFQAEFSLHC 147

Query: 141 ----------------------VDVKPISQEKIESE-----RALISQCGKPVVNVSYRPA 173
                                 + +   S   IES+      +     G P+ N   +P+
Sbjct: 148 ETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNS--QPS 205

Query: 174 YDQGGPVEILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEAC--ATHLHYKWIPVE 231
           +    PVEILPFLYLG A  ++  + L    I  +LNV+         A    YK IP+ 
Sbjct: 206 F----PVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPIS 261

Query: 232 DSHTADISSHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFD 291
           D  + ++S  F EAI FID  R K   VLVHC AGISRS T+ +AYLM+     + +A+D
Sbjct: 262 DHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYD 321

Query: 292 YIKQRRSMVSPNFGFMGQLLQYESEILPSTP 322
            +K ++S +SPNF FMGQLL +E  +  S+P
Sbjct: 322 IVKMKKSNISPNFNFMGQLLDFERTLGLSSP 352


>gi|153281158 dual specificity phosphatase 8 [Homo sapiens]
          Length = 625

 Score =  134 bits (337), Expect = 1e-31
 Identities = 106/344 (30%), Positives = 169/344 (49%), Gaps = 36/344 (10%)

Query: 6   LDGRQLRKMLRKEAAARCVVLDCRPYLAFAASNVRGSLNVNLNSVVLRRARGGAVSARYV 65
           +D ++L  +LR       +V+D R ++ + + +V  S+N+  + +V RR + G V+   +
Sbjct: 11  MDAKKLASLLRGGPGGP-LVIDSRSFVEYNSWHVLSSVNICCSKLVKRRLQQGKVTIAEL 69

Query: 66  LPDEAARARLLQEGGGGVAAVVVLDQGSRHWQKLREESAARVVLTSLLACLPAGPRVYFL 125
           +   AAR+   Q        VVV DQ +R    L  +S   ++L+ L  C  +   V  L
Sbjct: 70  I-QPAARS---QVEATEPQDVVVYDQSTRDASVLAADSFLSILLSKLDGCFDS---VAIL 122

Query: 126 KGGYETFYSEYPECCVDVKPISQEKIESERALISQCGKPVVNVSYRPAYDQGGPVEILPF 185
            GG+ TF S +P  C + KP +   +      +SQ   PV +V         G   ILP 
Sbjct: 123 TGGFATFSSCFPGLC-EGKPAALLPMS-----LSQPCLPVPSV---------GLTRILPH 167

Query: 186 LYLGSAYHASKCEFLANLHITALLNVSRRTSEA---CATHLHYKWIPVEDSHTADISSHF 242
           LYLGS       + +    I+ +LN S    +    C +   +  +P+ D++   +    
Sbjct: 168 LYLGSQKDVLNKDLMTQNGISYVLNASNSCPKPDFICESR--FMRVPINDNYCEKLLPWL 225

Query: 243 QEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRSMVSP 302
            ++I+FID  +    +V+VHC AGISRS TI +AY+MKT      +A+ ++K RR  +SP
Sbjct: 226 DKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISP 285

Query: 303 NFGFMGQLLQYESEIL--------PSTPNPQPPSCQGEAAGSSL 338
           NF F+GQLL+YE  +         P TP+  P      AAG+ L
Sbjct: 286 NFNFLGQLLEYERSLKLLAALQGDPGTPSGTPEPPPSPAAGAPL 329


>gi|38372911 dual specificity phosphatase 16 [Homo sapiens]
          Length = 665

 Score =  131 bits (330), Expect = 9e-31
 Identities = 96/315 (30%), Positives = 145/315 (46%), Gaps = 24/315 (7%)

Query: 15  LRKEAAARCVVLDCRPYLAFAASNVRGSLNVNLNSVVLRRARGGAVSARYVLPDEAARAR 74
           L +    + +++D RP++ +  S++  ++N+N + ++ RR +   V    ++   A    
Sbjct: 18  LLESGTEKVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQQDKVLITELIQHSAKHKV 77

Query: 75  LLQEGGGGVAAVVVLDQGSRHWQKLREESAARVVLTSLLACLPAGPRVYFLKGGYETFYS 134
            +         VVV DQ S+    L  +    V+L  L     +   V+ L GG+  F  
Sbjct: 78  DIDCS----QKVVVYDQSSQDVASLSSDCFLTVLLGKLEKSFNS---VHLLAGGFAEFSR 130

Query: 135 EYPECCVDVKPISQEKIESERALISQCGKPVVNVSYRPAYDQGGPVEILPFLYLGSAYHA 194
            +P  C       + K       ISQ   PV N+         GP  ILP LYLG     
Sbjct: 131 CFPGLC-------EGKSTLVPTCISQPCLPVANI---------GPTRILPNLYLGCQRDV 174

Query: 195 SKCEFLANLHITALLNVSRRTSEA-CATHLHYKWIPVEDSHTADISSHFQEAIDFIDCVR 253
              E +    I  +LN S    +       H+  +PV DS    I     +++DFI+  +
Sbjct: 175 LNKELMQQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAK 234

Query: 254 EKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRSMVSPNFGFMGQLLQY 313
              G VLVHC AGISRS TI +AY+MK     L EA+ ++K++R  +SPNF F+GQLL Y
Sbjct: 235 ASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDY 294

Query: 314 ESEILPSTPNPQPPS 328
           E +I   T    P S
Sbjct: 295 EKKIKNQTGASGPKS 309


>gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]
          Length = 482

 Score =  131 bits (330), Expect = 9e-31
 Identities = 88/325 (27%), Positives = 161/325 (49%), Gaps = 37/325 (11%)

Query: 24  VVLDCRPYLAFAASNVRGSLNVNL-NSVVLRRARGGAVSARYVLPDEAAR---ARLLQEG 79
           V++DCRP++ +  S+++G++++N  + +  RR + G ++   ++     +    R+  + 
Sbjct: 173 VIIDCRPFMEYNKSHIQGAVHINCADKISRRRLQQGKITVLDLISCREGKDSFKRIFSK- 231

Query: 80  GGGVAAVVVLDQGSRHWQKLREESAARVVLTSLLACLPAGPRVYFLKGGYETFYSEYPEC 139
                 ++V D+ +    ++       +VL SL      G     LKGG  +F   +   
Sbjct: 232 -----EIIVYDENTNEPSRVMPSQPLHIVLESLKR---EGKEPLVLKGGLSSFKQNHENL 283

Query: 140 CVDVKPISQ--EKIESERALISQCGKPVVNVSYRPAYDQGGPVEILPFLYLGSAYHASKC 197
           C +   + +  E      A  S   +P+      P  +      ILPFL+LG+   A   
Sbjct: 284 CDNSLQLQECREVGGGASAASSLLPQPIPTT---PDIENAELTPILPFLFLGNEQDAQDL 340

Query: 198 EFLANLHITALLNVSRRTSEACATHL----------HYKWIPVEDSHTADISSHFQEAID 247
           + +  L+I  ++NV+        THL          +YK +P  DS+  ++  +F+EA +
Sbjct: 341 DTMQRLNIGYVINVT--------THLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFE 392

Query: 248 FIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRSMVSPNFGFM 307
           FI+   + G  +L+HC+AG+SRS TI +AYLMK  +  + +A+ ++K +R ++SPN  FM
Sbjct: 393 FIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFM 452

Query: 308 GQLLQYESEILPS-TPNPQPPSCQG 331
           GQLL++E ++    TP    P   G
Sbjct: 453 GQLLEFEEDLNNGVTPRILTPKLMG 477


>gi|239047414 slingshot 1 isoform 1 [Homo sapiens]
          Length = 1049

 Score =  101 bits (251), Expect = 1e-21
 Identities = 55/136 (40%), Positives = 78/136 (57%)

Query: 179 PVEILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACATHLHYKWIPVEDSHTADI 238
           P  I   LYLGS ++AS  E L    +  +LNV+R           Y  I V D  T D+
Sbjct: 309 PSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDL 368

Query: 239 SSHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRS 298
            +H+ EA  FI+  +    K LVHC+ G+SRS +  +AY MK   + L++A++Y+KQ+RS
Sbjct: 369 LAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRS 428

Query: 299 MVSPNFGFMGQLLQYE 314
           +  PN GFM QL +YE
Sbjct: 429 ITRPNAGFMRQLSEYE 444


>gi|239047498 slingshot 1 isoform 3 [Homo sapiens]
          Length = 703

 Score =  101 bits (251), Expect = 1e-21
 Identities = 55/136 (40%), Positives = 78/136 (57%)

Query: 179 PVEILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACATHLHYKWIPVEDSHTADI 238
           P  I   LYLGS ++AS  E L    +  +LNV+R           Y  I V D  T D+
Sbjct: 320 PSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDL 379

Query: 239 SSHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRS 298
            +H+ EA  FI+  +    K LVHC+ G+SRS +  +AY MK   + L++A++Y+KQ+RS
Sbjct: 380 LAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRS 439

Query: 299 MVSPNFGFMGQLLQYE 314
           +  PN GFM QL +YE
Sbjct: 440 ITRPNAGFMRQLSEYE 455


>gi|239047441 slingshot 1 isoform 2 [Homo sapiens]
          Length = 692

 Score =  101 bits (251), Expect = 1e-21
 Identities = 55/136 (40%), Positives = 78/136 (57%)

Query: 179 PVEILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACATHLHYKWIPVEDSHTADI 238
           P  I   LYLGS ++AS  E L    +  +LNV+R           Y  I V D  T D+
Sbjct: 309 PSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDL 368

Query: 239 SSHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRS 298
            +H+ EA  FI+  +    K LVHC+ G+SRS +  +AY MK   + L++A++Y+KQ+RS
Sbjct: 369 LAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRS 428

Query: 299 MVSPNFGFMGQLLQYE 314
           +  PN GFM QL +YE
Sbjct: 429 ITRPNAGFMRQLSEYE 444


>gi|37674210 slingshot 2 [Homo sapiens]
          Length = 1423

 Score = 99.0 bits (245), Expect = 6e-21
 Identities = 51/142 (35%), Positives = 79/142 (55%)

Query: 179 PVEILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACATHLHYKWIPVEDSHTADI 238
           P +I   ++LGS ++AS  E L N  +  +LNV+R           Y  I V D    D+
Sbjct: 308 PTQIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFPGVFEYHNIRVYDEEATDL 367

Query: 239 SSHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRS 298
            +++ +   FI   ++ G K LVHC+ G+SRS +  +AY MK   + L  A+DY+K+RR+
Sbjct: 368 LAYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKERRT 427

Query: 299 MVSPNFGFMGQLLQYESEILPS 320
           +  PN  FM QL +Y+  +L S
Sbjct: 428 VTKPNPSFMRQLEEYQGILLAS 449


>gi|5902002 dual specificity phosphatase 14 [Homo sapiens]
          Length = 198

 Score = 96.7 bits (239), Expect = 3e-20
 Identities = 54/143 (37%), Positives = 74/143 (51%)

Query: 175 DQGGPVEILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACATHLHYKWIPVEDSH 234
           D GG  +I   L+LG    AS    L    IT ++N +            Y  +P+ D  
Sbjct: 23  DIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNFNWPQFEYVKVPLADMP 82

Query: 235 TADISSHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIK 294
            A I  +F    D I  V  K G  LVHC AG+SRS T+C+AYLMK     L EA++++K
Sbjct: 83  HAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVK 142

Query: 295 QRRSMVSPNFGFMGQLLQYESEI 317
            RR ++ PN GF  QL+ YE ++
Sbjct: 143 ARRPVIRPNVGFWRQLIDYERQL 165


>gi|21536333 dual specificity phosphatase 10 isoform b [Homo
           sapiens]
          Length = 140

 Score = 94.0 bits (232), Expect = 2e-19
 Identities = 43/109 (39%), Positives = 71/109 (65%), Gaps = 1/109 (0%)

Query: 224 HYKWIPVEDSHTADISSHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQ 283
           +YK +P  DS+  ++  +F+EA +FI+   + G  +L+HC+AG+SRS TI +AYLMK  +
Sbjct: 27  NYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTR 86

Query: 284 FRLKEAFDYIKQRRSMVSPNFGFMGQLLQYESEILPS-TPNPQPPSCQG 331
             + +A+ ++K +R ++SPN  FMGQLL++E ++    TP    P   G
Sbjct: 87  MTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDLNNGVTPRILTPKLMG 135


>gi|21536331 dual specificity phosphatase 10 isoform b [Homo
           sapiens]
          Length = 140

 Score = 94.0 bits (232), Expect = 2e-19
 Identities = 43/109 (39%), Positives = 71/109 (65%), Gaps = 1/109 (0%)

Query: 224 HYKWIPVEDSHTADISSHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQ 283
           +YK +P  DS+  ++  +F+EA +FI+   + G  +L+HC+AG+SRS TI +AYLMK  +
Sbjct: 27  NYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTR 86

Query: 284 FRLKEAFDYIKQRRSMVSPNFGFMGQLLQYESEILPS-TPNPQPPSCQG 331
             + +A+ ++K +R ++SPN  FMGQLL++E ++    TP    P   G
Sbjct: 87  MTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDLNNGVTPRILTPKLMG 135


>gi|29826315 dual specificity phosphatase 15 isoform a [Homo
           sapiens]
          Length = 235

 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 51/136 (37%), Positives = 73/136 (53%), Gaps = 1/136 (0%)

Query: 178 GPVEILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACATHLHYKWIPVEDSHTAD 237
           G  ++LP LYLG+   A   + L    IT ++++   + +     + Y  IPV D+    
Sbjct: 4   GMTKVLPGLYLGNFIDAKDLDQLGRNKITHIISI-HESPQPLLQDITYLRIPVADTPEVP 62

Query: 238 ISSHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRR 297
           I  HF+E I+FI C R  GG  LVHC AGISRS TI  AY+M       ++  + IK  R
Sbjct: 63  IKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKATR 122

Query: 298 SMVSPNFGFMGQLLQY 313
            + +PN GF  QL ++
Sbjct: 123 PIANPNPGFRQQLEEF 138


>gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo
           sapiens]
          Length = 217

 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 50/133 (37%), Positives = 71/133 (53%)

Query: 182 ILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACATHLHYKWIPVEDSHTADISSH 241
           I P+L LGS   A   + L    +T +LNV+     A  +   YK I + D    +I S+
Sbjct: 69  IKPWLLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSISILDLPETNILSY 128

Query: 242 FQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRSMVS 301
           F E  +FI+  + K G VLVHC AG+SR+  I + +LM ++Q     AF  +K  R  + 
Sbjct: 129 FPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPSIC 188

Query: 302 PNFGFMGQLLQYE 314
           PN GFM QL  Y+
Sbjct: 189 PNSGFMEQLRTYQ 201


>gi|239582767 slingshot homolog 3 [Homo sapiens]
          Length = 659

 Score = 89.4 bits (220), Expect = 5e-18
 Identities = 47/139 (33%), Positives = 76/139 (54%)

Query: 182 ILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACATHLHYKWIPVEDSHTADISSH 241
           I P LYLGS ++A+  E L    +T +LN++R           Y  + + D  +A +  H
Sbjct: 332 IFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPERFTYHNVRLWDEESAQLLPH 391

Query: 242 FQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRSMVS 301
           ++E   FI+  R +G  VLVHC+ G+SRS    +AY MK  +  L++A  ++++ R +  
Sbjct: 392 WKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRPIAR 451

Query: 302 PNFGFMGQLLQYESEILPS 320
           PN GF+ QL  Y+  +  S
Sbjct: 452 PNPGFLRQLQIYQGILTAS 470


>gi|51093845 dual specificity phosphatase 18 [Homo sapiens]
          Length = 188

 Score = 89.4 bits (220), Expect = 5e-18
 Identities = 48/140 (34%), Positives = 72/140 (51%)

Query: 178 GPVEILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACATHLHYKWIPVEDSHTAD 237
           G  +I   LY+ +   A+    L++  IT ++NVS          + Y  +PV DS  + 
Sbjct: 19  GLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTLYEDIQYMQVPVADSPNSR 78

Query: 238 ISSHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRR 297
           +   F    D I  V  K G+ L+HC AG+SRS  +C+AYLMK     L +A  + K  R
Sbjct: 79  LCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLLDAHTWTKSCR 138

Query: 298 SMVSPNFGFMGQLLQYESEI 317
            ++ PN GF  QL+ YE ++
Sbjct: 139 PIIRPNSGFWEQLIHYEFQL 158


>gi|13128968 dual specificity phosphatase 26 [Homo sapiens]
          Length = 211

 Score = 88.6 bits (218), Expect = 9e-18
 Identities = 58/143 (40%), Positives = 76/143 (53%), Gaps = 7/143 (4%)

Query: 181 EILPFLYLGSAYHASKCEFLANLHITALLNVS----RRTSEAC-ATHLHYKWIPVEDSHT 235
           E+ P LYLG    A+    L  L IT +LN S    R T EA     + Y  +   DS  
Sbjct: 64  EVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHDSPA 123

Query: 236 ADISSHFQEAIDFID-CVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIK 294
            D+S HFQ A DFI   + + GGK+LVHC  G+SRS T+ +AYLM      L EA   +K
Sbjct: 124 FDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKVK 183

Query: 295 QRRSMVSPNFGFMGQLLQYESEI 317
             R ++ PN GF+ QLL  +  +
Sbjct: 184 DHRGII-PNRGFLRQLLALDRRL 205


>gi|9910432 dual specificity phosphatase 22 [Homo sapiens]
          Length = 184

 Score = 88.2 bits (217), Expect = 1e-17
 Identities = 50/137 (36%), Positives = 78/137 (56%), Gaps = 1/137 (0%)

Query: 178 GPVEILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACATHLHYKWIPVEDSHTAD 237
           G  +ILP LY+G+   A   E L+   +T +L+V   ++      + Y  IP  DS + +
Sbjct: 4   GMNKILPGLYIGNFKDARDAEQLSKNKVTHILSV-HDSARPMLEGVKYLCIPAADSPSQN 62

Query: 238 ISSHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRR 297
           ++ HF+E+I FI   R +G   LVHC AG+SRS T+ +AY+M    F  ++A   ++  R
Sbjct: 63  LTRHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRAGR 122

Query: 298 SMVSPNFGFMGQLLQYE 314
           S  +PN GF  QL ++E
Sbjct: 123 SCANPNVGFQRQLQEFE 139


>gi|75750526 dual specificity phosphatase 28 [Homo sapiens]
          Length = 176

 Score = 87.4 bits (215), Expect = 2e-17
 Identities = 55/154 (35%), Positives = 77/154 (50%), Gaps = 8/154 (5%)

Query: 180 VEILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACATHLHYKWIPVEDSHTADIS 239
           V + P L+LGSA  A   E LA   +T  +NVSR+     A  +    +PV D    D+ 
Sbjct: 20  VRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPRAPGVAELRVPVFDDPAEDLL 79

Query: 240 SHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRSM 299
           +H +     ++     GG  LV+C+ G SRS  +C AYLM+ +   L +AF  +K  R +
Sbjct: 80  AHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSLAKAFQMVKSARPV 139

Query: 300 VSPNFGFMGQLLQYESEILPSTPNPQPPSC-QGE 332
             PN GF  QL +YE  +       Q  SC QGE
Sbjct: 140 AEPNPGFWSQLQKYEEAL-------QAQSCLQGE 166


>gi|225703077 dual specificity phosphatase 21 [Homo sapiens]
          Length = 190

 Score = 85.5 bits (210), Expect = 7e-17
 Identities = 45/137 (32%), Positives = 73/137 (53%)

Query: 181 EILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACATHLHYKWIPVEDSHTADISS 240
           +I   L+L +   A+    L++  ITA++N S          + Y  +PV D+  + +  
Sbjct: 24  QITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFEGIQYIKVPVTDARDSRLYD 83

Query: 241 HFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRSMV 300
            F    D I  +  + G+ L+HC AG+SRS ++C+AYLMK     L +A  + K RR ++
Sbjct: 84  FFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAHTWTKSRRPII 143

Query: 301 SPNFGFMGQLLQYESEI 317
            PN GF  QL+ YE ++
Sbjct: 144 RPNNGFWEQLINYEFKL 160


>gi|4758208 dual specificity phosphatase 3 [Homo sapiens]
          Length = 185

 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 51/147 (34%), Positives = 78/147 (53%), Gaps = 11/147 (7%)

Query: 181 EILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACA---------THLHYKWIPVE 231
           E+ P +Y+G+A  A     L  L IT +LN +   S             + + Y  I   
Sbjct: 32  EVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKAN 91

Query: 232 DSHTADISSHFQEAIDFID-CVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAF 290
           D+   ++S++F+ A DFID  + +K G+VLVHC  G SRSPT+ +AYLM  ++  +K A 
Sbjct: 92  DTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSAL 151

Query: 291 DYIKQRRSMVSPNFGFMGQLLQYESEI 317
             ++Q R  + PN GF+ QL Q    +
Sbjct: 152 SIVRQNRE-IGPNDGFLAQLCQLNDRL 177


>gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo
           sapiens]
          Length = 223

 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 53/143 (37%), Positives = 79/143 (55%), Gaps = 9/143 (6%)

Query: 181 EILPFLYLG--SAYHASKCEFLANLHITALLNVSRRTSEACATH------LHYKWIPVED 232
           EILP L+LG  S+   SK   L    IT ++ + R+  EA            Y  + + D
Sbjct: 31  EILPGLFLGPYSSAMKSKLPVLQKHGITHIICI-RQNIEANFIKPNFQQLFRYLVLDIAD 89

Query: 233 SHTADISSHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDY 292
           +   +I   F    +FID   + GGKVLVH  AGISRS    +AY+M+T   + ++AF Y
Sbjct: 90  NPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAY 149

Query: 293 IKQRRSMVSPNFGFMGQLLQYES 315
           +++RR  ++PN GF+ QL +YE+
Sbjct: 150 VQERRFCINPNAGFVHQLQEYEA 172


>gi|194733759 serine/threonine/tyrosine interacting protein [Homo
           sapiens]
          Length = 223

 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 53/143 (37%), Positives = 79/143 (55%), Gaps = 9/143 (6%)

Query: 181 EILPFLYLG--SAYHASKCEFLANLHITALLNVSRRTSEACATH------LHYKWIPVED 232
           EILP L+LG  S+   SK   L    IT ++ + R+  EA            Y  + + D
Sbjct: 31  EILPGLFLGPYSSAMKSKLPVLQKHGITHIICI-RQNIEANFIKPNFQQLFRYLVLDIAD 89

Query: 233 SHTADISSHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDY 292
           +   +I   F    +FID   + GGKVLVH  AGISRS    +AY+M+T   + ++AF Y
Sbjct: 90  NPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAY 149

Query: 293 IKQRRSMVSPNFGFMGQLLQYES 315
           +++RR  ++PN GF+ QL +YE+
Sbjct: 150 VQERRFCINPNAGFVHQLQEYEA 172


>gi|21687043 serine/threonine/tyrosine interacting protein [Homo
           sapiens]
          Length = 223

 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 53/143 (37%), Positives = 79/143 (55%), Gaps = 9/143 (6%)

Query: 181 EILPFLYLG--SAYHASKCEFLANLHITALLNVSRRTSEACATH------LHYKWIPVED 232
           EILP L+LG  S+   SK   L    IT ++ + R+  EA            Y  + + D
Sbjct: 31  EILPGLFLGPYSSAMKSKLPVLQKHGITHIICI-RQNIEANFIKPNFQQLFRYLVLDIAD 89

Query: 233 SHTADISSHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDY 292
           +   +I   F    +FID   + GGKVLVH  AGISRS    +AY+M+T   + ++AF Y
Sbjct: 90  NPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAY 149

Query: 293 IKQRRSMVSPNFGFMGQLLQYES 315
           +++RR  ++PN GF+ QL +YE+
Sbjct: 150 VQERRFCINPNAGFVHQLQEYEA 172


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,096,340
Number of Sequences: 37866
Number of extensions: 699818
Number of successful extensions: 2201
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 69
Number of HSP's successfully gapped in prelim test: 38
Number of HSP's that attempted gapping in prelim test: 2074
Number of HSP's gapped (non-prelim): 127
length of query: 384
length of database: 18,247,518
effective HSP length: 104
effective length of query: 280
effective length of database: 14,309,454
effective search space: 4006647120
effective search space used: 4006647120
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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