Guide to the Human Genome
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Search of human proteins with 62865635

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|62865635 squalene epoxidase [Homo sapiens]
         (574 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|62865635 squalene epoxidase [Homo sapiens]                        1142   0.0  
gi|23821023 interleukin 4 induced 1 isoform 1 precursor [Homo sa...    38   0.029
gi|27477089 interleukin 4 induced 1 isoform 2 [Homo sapiens]           38   0.029
gi|187960045 kynurenine 3-monooxygenase [Homo sapiens]                 37   0.049
gi|116256451 amine oxidase (flavin containing) domain 1 [Homo sa...    36   0.11 
gi|203098013 all-trans-13,14-dihydroretinol saturase [Homo sapiens]    33   0.71 
gi|91199540 dihydrolipoamide dehydrogenase precursor [Homo sapiens]    33   0.93 
gi|226437568 apoptosis-inducing factor, mitochondrion-associated...    32   1.2  
gi|65787454 apoptosis-inducing factor, mitochondrion-associated,...    32   1.2  
gi|21389617 apoptosis-inducing factor, mitochondrion-associated,...    32   1.2  
gi|65507253 hypothetical protein LOC55196 [Homo sapiens]               31   3.5  
gi|170172518 microtubule associated monoxygenase, calponin and L...    30   4.6  
gi|209862793 microtubule associated monoxygenase, calponin and L...    30   4.6  
gi|209862789 microtubule associated monoxygenase, calponin and L...    30   4.6  
gi|116284392 mucin 2 precursor [Homo sapiens]                          30   6.0  
gi|154813197 talpid3 protein [Homo sapiens]                            30   6.0  
gi|22035672 thioredoxin reductase 2 precursor [Homo sapiens]           30   7.9  
gi|32967307 coenzyme Q6 homolog isoform b [Homo sapiens]               30   7.9  
gi|32967305 coenzyme Q6 homolog isoform a [Homo sapiens]               30   7.9  

>gi|62865635 squalene epoxidase [Homo sapiens]
          Length = 574

 Score = 1142 bits (2955), Expect = 0.0
 Identities = 574/574 (100%), Positives = 574/574 (100%)

Query: 1   MWTFLGIATFTYFYKKFGDFITLANREVLLCVLVFLSLGLVLSYRCRHRNGGLLGRQQSG 60
           MWTFLGIATFTYFYKKFGDFITLANREVLLCVLVFLSLGLVLSYRCRHRNGGLLGRQQSG
Sbjct: 1   MWTFLGIATFTYFYKKFGDFITLANREVLLCVLVFLSLGLVLSYRCRHRNGGLLGRQQSG 60

Query: 61  SQFALFSDILSGLPFIGFFWAKSPPESENKEQLEARRRRKGTNISETSLIGTAACTSTSS 120
           SQFALFSDILSGLPFIGFFWAKSPPESENKEQLEARRRRKGTNISETSLIGTAACTSTSS
Sbjct: 61  SQFALFSDILSGLPFIGFFWAKSPPESENKEQLEARRRRKGTNISETSLIGTAACTSTSS 120

Query: 121 QNDPEVIIVGAGVLGSALAAVLSRDGRKVTVIERDLKEPDRIVGEFLQPGGYHVLKDLGL 180
           QNDPEVIIVGAGVLGSALAAVLSRDGRKVTVIERDLKEPDRIVGEFLQPGGYHVLKDLGL
Sbjct: 121 QNDPEVIIVGAGVLGSALAAVLSRDGRKVTVIERDLKEPDRIVGEFLQPGGYHVLKDLGL 180

Query: 181 GDTVEGLDAQVVNGYMIHDQESKSEVQIPYPLSENNQVQSGRAFHHGRFIMSLRKAAMAE 240
           GDTVEGLDAQVVNGYMIHDQESKSEVQIPYPLSENNQVQSGRAFHHGRFIMSLRKAAMAE
Sbjct: 181 GDTVEGLDAQVVNGYMIHDQESKSEVQIPYPLSENNQVQSGRAFHHGRFIMSLRKAAMAE 240

Query: 241 PNAKFIEGVVLQLLEEDDVVMGVQYKDKETGDIKELHAPLTVVADGLFSKFRKSLVSNKV 300
           PNAKFIEGVVLQLLEEDDVVMGVQYKDKETGDIKELHAPLTVVADGLFSKFRKSLVSNKV
Sbjct: 241 PNAKFIEGVVLQLLEEDDVVMGVQYKDKETGDIKELHAPLTVVADGLFSKFRKSLVSNKV 300

Query: 301 SVSSHFVGFLMKNAPQFKANHAELILANPSPVLIYQISSSETRVLVDIRGEMPRNLREYM 360
           SVSSHFVGFLMKNAPQFKANHAELILANPSPVLIYQISSSETRVLVDIRGEMPRNLREYM
Sbjct: 301 SVSSHFVGFLMKNAPQFKANHAELILANPSPVLIYQISSSETRVLVDIRGEMPRNLREYM 360

Query: 361 VEKIYPQIPDHLKEPFLEATDNSHLRSMPASFLPPSSVKKRGVLLLGDAYNMRHPLTGGG 420
           VEKIYPQIPDHLKEPFLEATDNSHLRSMPASFLPPSSVKKRGVLLLGDAYNMRHPLTGGG
Sbjct: 361 VEKIYPQIPDHLKEPFLEATDNSHLRSMPASFLPPSSVKKRGVLLLGDAYNMRHPLTGGG 420

Query: 421 MTVAFKDIKLWRKLLKGIPDLYDDAAIFEAKKSFYWARKTSHSFVVNILAQALYELFSAT 480
           MTVAFKDIKLWRKLLKGIPDLYDDAAIFEAKKSFYWARKTSHSFVVNILAQALYELFSAT
Sbjct: 421 MTVAFKDIKLWRKLLKGIPDLYDDAAIFEAKKSFYWARKTSHSFVVNILAQALYELFSAT 480

Query: 481 DDSLHQLRKACFLYFKLGGECVAGPVGLLSVLSPNPLVLIGHFFAVAIYAVYFCFKSEPW 540
           DDSLHQLRKACFLYFKLGGECVAGPVGLLSVLSPNPLVLIGHFFAVAIYAVYFCFKSEPW
Sbjct: 481 DDSLHQLRKACFLYFKLGGECVAGPVGLLSVLSPNPLVLIGHFFAVAIYAVYFCFKSEPW 540

Query: 541 ITKPRALLSSGAVLYKACSVIFPLIYSEMKYMVH 574
           ITKPRALLSSGAVLYKACSVIFPLIYSEMKYMVH
Sbjct: 541 ITKPRALLSSGAVLYKACSVIFPLIYSEMKYMVH 574


>gi|23821023 interleukin 4 induced 1 isoform 1 precursor [Homo
           sapiens]
          Length = 567

 Score = 37.7 bits (86), Expect = 0.029
 Identities = 27/71 (38%), Positives = 34/71 (47%), Gaps = 15/71 (21%)

Query: 126 VIIVGAGVLGSALAAVLSRDGRKVTVIERDLKEPDRI-------------VGEFLQPGGY 172
           VI+VGAGV G   A VLS  G KVT++E D +   RI             +G    P  +
Sbjct: 62  VIVVGAGVAGLVAAKVLSDAGHKVTILEADNRIGGRIFTYRDQNTGWIGELGAMRMPSSH 121

Query: 173 HVLKDL--GLG 181
            +L  L  GLG
Sbjct: 122 RILHKLCQGLG 132


>gi|27477089 interleukin 4 induced 1 isoform 2 [Homo sapiens]
          Length = 589

 Score = 37.7 bits (86), Expect = 0.029
 Identities = 27/71 (38%), Positives = 34/71 (47%), Gaps = 15/71 (21%)

Query: 126 VIIVGAGVLGSALAAVLSRDGRKVTVIERDLKEPDRI-------------VGEFLQPGGY 172
           VI+VGAGV G   A VLS  G KVT++E D +   RI             +G    P  +
Sbjct: 84  VIVVGAGVAGLVAAKVLSDAGHKVTILEADNRIGGRIFTYRDQNTGWIGELGAMRMPSSH 143

Query: 173 HVLKDL--GLG 181
            +L  L  GLG
Sbjct: 144 RILHKLCQGLG 154


>gi|187960045 kynurenine 3-monooxygenase [Homo sapiens]
          Length = 486

 Score = 37.0 bits (84), Expect = 0.049
 Identities = 78/336 (23%), Positives = 129/336 (38%), Gaps = 39/336 (11%)

Query: 125 EVIIVGAGVLGSALAAVLSRDGRKVTVIERDLKEPDRI--------VGEFLQPGGYHVLK 176
           +V ++G G++GS  A  L++   ++ V E   +E  R+        +   L   G   LK
Sbjct: 10  KVAVIGGGLVGSLQACFLAKRNFQIDVYE--AREDTRVATFTRGRSINLALSHRGRQALK 67

Query: 177 DLGLGDTV--EGLDAQVVNGYMIHDQESKSEVQIPYPLSENNQVQSGRAFHHGRFIMSLR 234
            +GL D +  +G+    +   MIH    K    IPY       +   R          L 
Sbjct: 68  AVGLEDQIVSQGIP---MRARMIHSLSGKKSA-IPYGTKSQYILSVSRE----NLNKDLL 119

Query: 235 KAAMAEPNAKFIEGVVLQLLEEDDVVMGVQYKDKETGDIKELHAPLTVVADGLFSKFRKS 294
            AA   PN K      L     ++ ++ V   DK     K++   L V  DG +S  R  
Sbjct: 120 TAAEKYPNVKMHFNHRLLKCNPEEGMITVLGSDKVP---KDVTCDLIVGCDGAYSTVRSH 176

Query: 295 LVSN-KVSVSSHFV--GFLMKNAP------QFKANHAELILANP-SPVLIYQISSSETRV 344
           L+   +   S  ++  G++    P        + N+  +   N    + +  ++ S T  
Sbjct: 177 LMKKPRFDYSQQYIPHGYMELTIPPKNGDYAMEPNYLHIWPRNTFMMIALPNMNKSFTCT 236

Query: 345 LVDIRGEMPRNLREYMV----EKIYPQIPDHLKEPFLEATDNSHLRSMPASFLPPSSVK- 399
           L     E  + L    V    +K +P     + E  L   D   L + P   +  SS   
Sbjct: 237 LFMPFEEFEKLLTSNDVVDFFQKYFPDAIPLIGEKLL-VQDFFLLPAQPMISVKCSSFHF 295

Query: 400 KRGVLLLGDAYNMRHPLTGGGMTVAFKDIKLWRKLL 435
           K   +LLGDA +   P  G GM   F+D  ++ +L+
Sbjct: 296 KSHCVLLGDAAHAIVPFFGQGMNAGFEDCLVFDELM 331


>gi|116256451 amine oxidase (flavin containing) domain 1 [Homo
           sapiens]
          Length = 590

 Score = 35.8 bits (81), Expect = 0.11
 Identities = 32/96 (33%), Positives = 39/96 (40%), Gaps = 12/96 (12%)

Query: 99  RKGTNISETSLIGTAACTSTSSQNDPEVIIVGAGVLGSALAAVLSRDGRKVTVIERDLKE 158
           RKG   +    +G          ++  VII+GAG  G A A  L   G KVTV+E     
Sbjct: 226 RKGLINTGVLSVGADQYLLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLE----A 281

Query: 159 PDRIVGEFLQPGGYHVLKDLGLGDTVEGLDAQVVNG 194
            DRI        G  V  D        G  AQ+VNG
Sbjct: 282 KDRI--------GGRVWDDKSFKGVTVGRGAQIVNG 309


>gi|203098013 all-trans-13,14-dihydroretinol saturase [Homo sapiens]
          Length = 610

 Score = 33.1 bits (74), Expect = 0.71
 Identities = 13/33 (39%), Positives = 25/33 (75%)

Query: 125 EVIIVGAGVLGSALAAVLSRDGRKVTVIERDLK 157
           +V+++G+G  G A AA+L++ G++V V+E+  K
Sbjct: 69  DVVVIGSGFGGLAAAAILAKAGKRVLVLEQHTK 101


>gi|91199540 dihydrolipoamide dehydrogenase precursor [Homo sapiens]
          Length = 509

 Score = 32.7 bits (73), Expect = 0.93
 Identities = 16/53 (30%), Positives = 29/53 (54%), Gaps = 1/53 (1%)

Query: 101 GTNISETSLIGTAACTSTSSQNDPEVIIVGAGVLGSALAAVLSRDGRKVTVIE 153
           G  I E +++ +    S     + +++++GAGV+G  L +V  R G  VT +E
Sbjct: 192 GITIDEDTIVSSTGALSLKKVPE-KMVVIGAGVIGVELGSVWQRLGADVTAVE 243


>gi|226437568 apoptosis-inducing factor, mitochondrion-associated, 3
           isoform 3 [Homo sapiens]
          Length = 604

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 16/40 (40%), Positives = 24/40 (60%)

Query: 126 VIIVGAGVLGSALAAVLSRDGRKVTVIERDLKEPDRIVGE 165
           V++VGAG LG  +AA L+     V+V+E +     R +GE
Sbjct: 341 VVVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRFLGE 380


>gi|65787454 apoptosis-inducing factor, mitochondrion-associated, 3
           isoform 2 [Homo sapiens]
          Length = 598

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 16/40 (40%), Positives = 24/40 (60%)

Query: 126 VIIVGAGVLGSALAAVLSRDGRKVTVIERDLKEPDRIVGE 165
           V++VGAG LG  +AA L+     V+V+E +     R +GE
Sbjct: 335 VVVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRFLGE 374


>gi|21389617 apoptosis-inducing factor, mitochondrion-associated, 3
           isoform 1 [Homo sapiens]
          Length = 605

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 16/40 (40%), Positives = 24/40 (60%)

Query: 126 VIIVGAGVLGSALAAVLSRDGRKVTVIERDLKEPDRIVGE 165
           V++VGAG LG  +AA L+     V+V+E +     R +GE
Sbjct: 335 VVVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRFLGE 374


>gi|65507253 hypothetical protein LOC55196 [Homo sapiens]
          Length = 1747

 Score = 30.8 bits (68), Expect = 3.5
 Identities = 31/120 (25%), Positives = 53/120 (44%), Gaps = 4/120 (3%)

Query: 287 LFSKFRKSLVSNKVSVSSHFVGFLMKNAPQFKANHAELILANPSPVLIYQISSSETRVLV 346
           L S  R  + S+  +  SH   F   N P   A  ++LI ++   + +  I S+ TR+ V
Sbjct: 120 LNSPMRNPVHSHIGATVSHQTDF-GANVPNMPALQSQLITSDTYSMQMQMIPSNSTRLPV 178

Query: 347 DIRGE--MPRNLREYMVEKIYPQIPDHLKEPFLEATDNSHLRSMPASFLPPSSVKKRGVL 404
             +G   + ++  E  V+     I   L  P        + R  P SFLP S+++K+  +
Sbjct: 179 AYQGNQGLNQSFSEQQVDWTQQCISKGLTYPDYRPPPKLY-RYSPQSFLPDSTIQKQNFI 237


>gi|170172518 microtubule associated monoxygenase, calponin and LIM
           domain containing 3 isoform 3 [Homo sapiens]
          Length = 966

 Score = 30.4 bits (67), Expect = 4.6
 Identities = 26/67 (38%), Positives = 34/67 (50%), Gaps = 9/67 (13%)

Query: 114 ACTSTSSQNDPEVIIVGAGVLGSALAAVLSRDGRKVTVIE-RDLKEPDRIVGEFLQPGGY 172
           ACT+T      + +I+GAG  G   A  LS  G KV VIE RD    + ++   L P   
Sbjct: 83  ACTNT------KCLIIGAGPCGLRTAIDLSLLGAKVVVIEKRDAFSRNNVL--HLWPFTI 134

Query: 173 HVLKDLG 179
           H L+ LG
Sbjct: 135 HDLRGLG 141


>gi|209862793 microtubule associated monoxygenase, calponin and LIM
           domain containing 3 isoform 2 [Homo sapiens]
          Length = 1073

 Score = 30.4 bits (67), Expect = 4.6
 Identities = 26/67 (38%), Positives = 34/67 (50%), Gaps = 9/67 (13%)

Query: 114 ACTSTSSQNDPEVIIVGAGVLGSALAAVLSRDGRKVTVIE-RDLKEPDRIVGEFLQPGGY 172
           ACT+T      + +I+GAG  G   A  LS  G KV VIE RD    + ++   L P   
Sbjct: 83  ACTNT------KCLIIGAGPCGLRTAIDLSLLGAKVVVIEKRDAFSRNNVL--HLWPFTI 134

Query: 173 HVLKDLG 179
           H L+ LG
Sbjct: 135 HDLRGLG 141


>gi|209862789 microtubule associated monoxygenase, calponin and LIM
           domain containing 3 isoform 1 [Homo sapiens]
          Length = 2002

 Score = 30.4 bits (67), Expect = 4.6
 Identities = 26/67 (38%), Positives = 34/67 (50%), Gaps = 9/67 (13%)

Query: 114 ACTSTSSQNDPEVIIVGAGVLGSALAAVLSRDGRKVTVIE-RDLKEPDRIVGEFLQPGGY 172
           ACT+T      + +I+GAG  G   A  LS  G KV VIE RD    + ++   L P   
Sbjct: 83  ACTNT------KCLIIGAGPCGLRTAIDLSLLGAKVVVIEKRDAFSRNNVL--HLWPFTI 134

Query: 173 HVLKDLG 179
           H L+ LG
Sbjct: 135 HDLRGLG 141


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 30.0 bits (66), Expect = 6.0
 Identities = 28/111 (25%), Positives = 52/111 (46%), Gaps = 7/111 (6%)

Query: 100 KGTNISETSLIGTAA-CTSTSSQNDPEVIIVGAGVLGSALAAVLSRDGRKVTVIERDLKE 158
           KG +    +L+G  A C ST  Q   + +++ A    + +  V   DG  V + E  +  
Sbjct: 419 KGDHNDSYALLGELAPCGSTDKQTCLKTVVLLADKKKNVV--VFKSDG-SVLLNELQVNL 475

Query: 159 PDRIVGEF--LQPGGYHVLKDLGLGDTVEGLDAQVVNGYMIHDQESKSEVQ 207
           P  +   F   +P  YH++  + +G  ++   A V+  ++  DQ S+ +VQ
Sbjct: 476 P-HVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQ 525


>gi|154813197 talpid3 protein [Homo sapiens]
          Length = 1472

 Score = 30.0 bits (66), Expect = 6.0
 Identities = 27/83 (32%), Positives = 40/83 (48%), Gaps = 15/83 (18%)

Query: 209  PYPLSENNQVQSGRAFH-----HGRFIMSLRKAAMAEPNAKFIEGVVLQLLEEDDVVMGV 263
            P PLS      SG  +      HG   MSL +  + EPN+K +    L   +E+DV + V
Sbjct: 1302 PKPLSRQFDTVSGSIYEDSCASHGP--MSLGELEL-EPNSKLVLPTTLLTAQENDVNLPV 1358

Query: 264  ------QYKDKETGDIKEL-HAP 279
                  QY+ K+  D+K++ H P
Sbjct: 1359 AAEDFSQYQLKQNQDVKQVEHKP 1381


>gi|22035672 thioredoxin reductase 2 precursor [Homo sapiens]
          Length = 524

 Score = 29.6 bits (65), Expect = 7.9
 Identities = 15/41 (36%), Positives = 25/41 (60%)

Query: 113 AACTSTSSQNDPEVIIVGAGVLGSALAAVLSRDGRKVTVIE 153
           AA  + + Q D ++++VG G  G A A   ++ GRKV V++
Sbjct: 29  AARGAAAGQRDYDLLVVGGGSGGLACAKEAAQLGRKVAVVD 69


>gi|32967307 coenzyme Q6 homolog isoform b [Homo sapiens]
          Length = 393

 Score = 29.6 bits (65), Expect = 7.9
 Identities = 13/26 (50%), Positives = 17/26 (65%)

Query: 403 VLLLGDAYNMRHPLTGGGMTVAFKDI 428
           V L+GDA +  HPL G G+ + F DI
Sbjct: 286 VALIGDAAHRVHPLAGQGVNMGFGDI 311


>gi|32967305 coenzyme Q6 homolog isoform a [Homo sapiens]
          Length = 468

 Score = 29.6 bits (65), Expect = 7.9
 Identities = 13/26 (50%), Positives = 17/26 (65%)

Query: 403 VLLLGDAYNMRHPLTGGGMTVAFKDI 428
           V L+GDA +  HPL G G+ + F DI
Sbjct: 361 VALIGDAAHRVHPLAGQGVNMGFGDI 386


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.138    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,331,970
Number of Sequences: 37866
Number of extensions: 937938
Number of successful extensions: 2108
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 2093
Number of HSP's gapped (non-prelim): 23
length of query: 574
length of database: 18,247,518
effective HSP length: 108
effective length of query: 466
effective length of database: 14,157,990
effective search space: 6597623340
effective search space used: 6597623340
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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