Guide to the Human Genome
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Search of human proteins with 62420888

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|62420888 dipeptidyl peptidase 7 preproprotein [Homo sapiens]
         (492 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|62420888 dipeptidyl peptidase 7 preproprotein [Homo sapiens]      1013   0.0  
gi|4826940 prolylcarboxypeptidase isoform 1 preproprotein [Homo ...   367   e-101
gi|117306169 prolylcarboxypeptidase isoform 2 preproprotein [Hom...   354   9e-98
gi|5031993 protease, serine, 16 [Homo sapiens]                        167   2e-41
gi|98986321 gliomedin [Homo sapiens]                                   31   2.9  
gi|119220554 serine palmitoyltransferase, long chain base subuni...    30   5.0  
gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens]           29   8.5  
gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens]           29   8.5  
gi|52486251 phospholipase A2, group VI isoform b [Homo sapiens]        29   8.5  
gi|52486194 phospholipase A2, group VI isoform a [Homo sapiens]        29   8.5  
gi|91982767 semaphorin 5B isoform 1 [Homo sapiens]                     29   8.5  
gi|9966764 lysophospholipase II [Homo sapiens]                         29   8.5  

>gi|62420888 dipeptidyl peptidase 7 preproprotein [Homo sapiens]
          Length = 492

 Score = 1013 bits (2620), Expect = 0.0
 Identities = 492/492 (100%), Positives = 492/492 (100%)

Query: 1   MGSAPWAPVLLLALGLRGLQAGARRAPDPGFQERFFQQRLDHFNFERFGNKTFPQRFLVS 60
           MGSAPWAPVLLLALGLRGLQAGARRAPDPGFQERFFQQRLDHFNFERFGNKTFPQRFLVS
Sbjct: 1   MGSAPWAPVLLLALGLRGLQAGARRAPDPGFQERFFQQRLDHFNFERFGNKTFPQRFLVS 60

Query: 61  DRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQS 120
           DRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQS
Sbjct: 61  DRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQS 120

Query: 121 TQRGHTELLTVEQALADFAELLRALRRDLGAQDAPAIAFGGSYGGMLSAYLRMKYPHLVA 180
           TQRGHTELLTVEQALADFAELLRALRRDLGAQDAPAIAFGGSYGGMLSAYLRMKYPHLVA
Sbjct: 121 TQRGHTELLTVEQALADFAELLRALRRDLGAQDAPAIAFGGSYGGMLSAYLRMKYPHLVA 180

Query: 181 GALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKDLFLQGAYDTVR 240
           GALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKDLFLQGAYDTVR
Sbjct: 181 GALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKDLFLQGAYDTVR 240

Query: 241 WEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEA 300
           WEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEA
Sbjct: 241 WEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEA 300

Query: 301 QRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFA 360
           QRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFA
Sbjct: 301 QRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFA 360

Query: 361 SNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPW 420
           SNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPW
Sbjct: 361 SNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPW 420

Query: 421 AGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQ 480
           AGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQ
Sbjct: 421 AGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQ 480

Query: 481 QPALRGGPRLSL 492
           QPALRGGPRLSL
Sbjct: 481 QPALRGGPRLSL 492


>gi|4826940 prolylcarboxypeptidase isoform 1 preproprotein [Homo
           sapiens]
          Length = 496

 Score =  367 bits (941), Expect = e-101
 Identities = 205/486 (42%), Positives = 284/486 (58%), Gaps = 29/486 (5%)

Query: 4   APWAPVLLL----ALGLRGLQAGARRAPD--PGFQERFFQQRLDHFNFERFGNKTFPQRF 57
           APWA + L     ALG   L       P     +   +FQQ++DHF F     KTF QR+
Sbjct: 15  APWATIALRPALRALGSLHLPTNPTSLPAVAKNYSVLYFQQKVDHFGFNTV--KTFNQRY 72

Query: 58  LVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFG 117
           LV+D++W +  G I FYTGNEGD+  F NN+ F+ ++A E  A+LVFAEHRYYG+SLPFG
Sbjct: 73  LVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFMWDVAEELKAMLVFAEHRYYGESLPFG 132

Query: 118 AQSTQRG-HTELLTVEQALADFAELLRALRRDL-GAQDAPAIAFGGSYGGMLSAYLRMKY 175
             S +   H   LT EQALADFAEL++ L+R + GA++ P IA GGSYGGML+A+ RMKY
Sbjct: 133 DNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKY 192

Query: 176 PHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKDLFLQGA 235
           PH+V GALAASAP+     L     F + VT DF    P C++ +  ++  I  L   G+
Sbjct: 193 PHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPHCSESIHRSWDAINRLSNTGS 252

Query: 236 YDTVRWEFGT---CQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVG 292
              ++W  G    C PL+ + D+  L  +    +  LAM+DYPY ++FL PLPA P+KV 
Sbjct: 253 --GLQWLTGALHLCSPLTSQ-DIQHLKDWISETWVNLAMVDYPYASNFLQPLPAWPIKVV 309

Query: 293 CDRL----LSEAQRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWD 348
           C  L    +S++  +  +     + YN SG   C +I     S     G         W 
Sbjct: 310 CQYLKNPNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETATSSLGTLG---------WS 360

Query: 349 YQACTEINLTFASNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAAS 408
           YQACTE+ + F +N V DMF    +  +     C   WGV PRP W+ T + G ++ + +
Sbjct: 361 YQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHT 420

Query: 409 NIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATI 468
           NI+FSNG LDPW+GGG+ ++++ +++AVTI  GAHHLDLR  +  DP SV+ AR LE   
Sbjct: 421 NIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDLRTKNALDPMSVLLARSLEVRH 480

Query: 469 IGEWVK 474
           +  W++
Sbjct: 481 MKNWIR 486


>gi|117306169 prolylcarboxypeptidase isoform 2 preproprotein [Homo
           sapiens]
          Length = 517

 Score =  354 bits (909), Expect = 9e-98
 Identities = 192/444 (43%), Positives = 267/444 (60%), Gaps = 23/444 (5%)

Query: 40  LDHFNFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERG 99
           +DHF F     KTF QR+LV+D++W +  G I FYTGNEGD+  F NN+ F+ ++A E  
Sbjct: 78  VDHFGFNTV--KTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFMWDVAEELK 135

Query: 100 ALLVFAEHRYYGKSLPFGAQSTQRG-HTELLTVEQALADFAELLRALRRDL-GAQDAPAI 157
           A+LVFAEHRYYG+SLPFG  S +   H   LT EQALADFAEL++ L+R + GA++ P I
Sbjct: 136 AMLVFAEHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVI 195

Query: 158 AFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCT 217
           A GGSYGGML+A+ RMKYPH+V GALAASAP+     L     F + VT DF    P C+
Sbjct: 196 AIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPHCS 255

Query: 218 QGVREAFRQIKDLFLQGAYDTVRWEFGT---CQPLSDEKDLTQLFMFARNAFTVLAMMDY 274
           + +  ++  I  L   G+   ++W  G    C PL+ + D+  L  +    +  LAM+DY
Sbjct: 256 ESIHRSWDAINRLSNTGS--GLQWLTGALHLCSPLTSQ-DIQHLKDWISETWVNLAMVDY 312

Query: 275 PYPTDFLGPLPANPVKVGCDRL----LSEAQRITGLRALAGLVYNASGSEHCYDIYRLYH 330
           PY ++FL PLPA P+KV C  L    +S++  +  +     + YN SG   C +I     
Sbjct: 313 PYASNFLQPLPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETAT 372

Query: 331 SCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPFTDELRQRYCLDTWGVWP 390
           S     G         W YQACTE+ + F +N V DMF    +  +     C   WGV P
Sbjct: 373 SSLGTLG---------WSYQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRP 423

Query: 391 RPDWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRAS 450
           RP W+ T + G ++ + +NI+FSNG LDPW+GGG+ ++++ +++AVTI  GAHHLDLR  
Sbjct: 424 RPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDLRTK 483

Query: 451 HPEDPASVVEARKLEATIIGEWVK 474
           +  DP SV+ AR LE   +  W++
Sbjct: 484 NALDPMSVLLARSLEVRHMKNWIR 507


>gi|5031993 protease, serine, 16 [Homo sapiens]
          Length = 514

 Score =  167 bits (424), Expect = 2e-41
 Identities = 148/485 (30%), Positives = 212/485 (43%), Gaps = 38/485 (7%)

Query: 14  LGLRGLQAGARRAPDPGFQERFFQQRLDHFNFERFGNKTFPQRFLVSDRFWVRGEGPIFF 73
           LGL  L  GA   P  G+ E    Q LD FN      ++F QR+ V+D+ WV  +GPIF 
Sbjct: 45  LGL-SLGPGAAALPKVGWLE----QLLDPFNVS--DRRSFLQRYWVNDQHWVGQDGPIFL 97

Query: 74  YTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQSTQRGHTELLTVEQ 133
           + G EG +   +      A LA   GAL++  EHR+YG S+P G    +      L+   
Sbjct: 98  HLGGEGSLGPGSVMRGHPAALAPAWGALVISLEHRFYGLSIPAG--GLEMAQLRFLSSRL 155

Query: 134 ALADFAELLRALRRDLG-AQDAPAIAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAV 192
           ALAD      AL R    +  +P I FGGSY G L+A+ R+K+PHL+  ++A+SAPV AV
Sbjct: 156 ALADVVSARLALSRLFNISSSSPWICFGGSYAGSLAAWARLKFPHLIFASVASSAPVRAV 215

Query: 193 AGLGDSNQFF-RDVTADFEGQSPKCTQGVREAFRQIKDLFLQG--AYDTVRWEFGTCQPL 249
               + N    R + +   G S +C   V  AF +++     G  A   +R E   C PL
Sbjct: 216 LDFSEYNDVVSRSLMSTAIGGSLECRAAVSVAFAEVERRLRSGGAAQAALRTELSACGPL 275

Query: 250 SDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLL------SEAQRI 303
              ++  +L      A   L      Y      PL    V+  C  LL      S +   
Sbjct: 276 GRAENQAELL----GALQALVGGVVQYDGQTGAPL---SVRQLCGLLLGGGGNRSHSTPY 328

Query: 304 TGLRALAGLVYNASGSEHCYDIYR----LYHSCADPTGCGTGPDARAWDYQACTEINLTF 359
            GLR    +V ++ G + C    R          +P   G G   R W YQ CTE     
Sbjct: 329 CGLRRAVQIVLHSLG-QKCLSFSRAETVAQLRSTEPQLSGVGD--RQWLYQTCTEFGFYV 385

Query: 360 ASNNVTDMFPDLPF----TDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNG 415
              N    F  LP      D   Q + L    V  +      S++GG    A+ ++F NG
Sbjct: 386 TCENPRCPFSQLPALPSQLDLCEQVFGLSALSV-AQAVAQTNSYYGGQTPGANKVLFVNG 444

Query: 416 NLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKA 475
           + DPW    + + L +S   + I+ G+H LD+    P D  S+   R+     +  W+K 
Sbjct: 445 DTDPWHVLSVTQALGSSESTLLIRTGSHCLDMAPERPSDSPSLRLGRQNIFQQLQTWLKL 504

Query: 476 ARREQ 480
           A+  Q
Sbjct: 505 AKESQ 509


>gi|98986321 gliomedin [Homo sapiens]
          Length = 551

 Score = 30.8 bits (68), Expect = 2.9
 Identities = 36/129 (27%), Positives = 54/129 (41%), Gaps = 6/129 (4%)

Query: 76  GNEGDV-WAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQSTQRGHTELLTVEQA 134
           G  GD  W      A VA L+A   A  VFA  ++ G S    A   QRG  +    + A
Sbjct: 7   GGRGDAGWGLRGALAAVALLSALNAAGTVFALCQWRGLSSALRALEAQRGREQ--REDSA 64

Query: 135 LADF-AELLRALRRDLGAQDAPAIAFGG--SYGGMLSAYLRMKYPHLVAGALAASAPVLA 191
           L  F AEL RA R        PA +     S+ G  + ++R +   ++     +  P+  
Sbjct: 65  LRSFLAELSRAPRGASAPPQDPASSARNKRSHSGEPAPHIRAESHDMLMMMTYSMVPIRV 124

Query: 192 VAGLGDSNQ 200
           +  L +S +
Sbjct: 125 MVDLCNSTK 133


>gi|119220554 serine palmitoyltransferase, long chain base subunit 3
           [Homo sapiens]
          Length = 552

 Score = 30.0 bits (66), Expect = 5.0
 Identities = 15/42 (35%), Positives = 21/42 (50%)

Query: 10  LLLALGLRGLQAGARRAPDPGFQERFFQQRLDHFNFERFGNK 51
           L L +GL G   G +R        R+F+QRL    F  +GN+
Sbjct: 415 LKLIMGLDGTTQGLQRVQQLAKNTRYFRQRLQEMGFIIYGNE 456


>gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens]
          Length = 904

 Score = 29.3 bits (64), Expect = 8.5
 Identities = 16/52 (30%), Positives = 25/52 (48%), Gaps = 8/52 (15%)

Query: 277 PTDFLGPLPANPVK--------VGCDRLLSEAQRITGLRALAGLVYNASGSE 320
           P+ FLG  PA+P +        +G D +  E +++   R   GL +N  G E
Sbjct: 433 PSSFLGQTPASPARYSPVSKAVLGDDEITREPRKVVLHRGSTGLGFNIVGGE 484


>gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens]
          Length = 926

 Score = 29.3 bits (64), Expect = 8.5
 Identities = 16/52 (30%), Positives = 25/52 (48%), Gaps = 8/52 (15%)

Query: 277 PTDFLGPLPANPVK--------VGCDRLLSEAQRITGLRALAGLVYNASGSE 320
           P+ FLG  PA+P +        +G D +  E +++   R   GL +N  G E
Sbjct: 433 PSSFLGQTPASPARYSPVSKAVLGDDEITREPRKVVLHRGSTGLGFNIVGGE 484


>gi|52486251 phospholipase A2, group VI isoform b [Homo sapiens]
          Length = 752

 Score = 29.3 bits (64), Expect = 8.5
 Identities = 26/77 (33%), Positives = 35/77 (45%), Gaps = 11/77 (14%)

Query: 60  SDRFWVRGEGPIFFYTGNEGDVWAFA------NNSAF-VAELAAERGALLVFAEHRYYGK 112
           SDR  VR EG +  +       W         + S F + +L  E  AL+ F  H+Y  +
Sbjct: 35  SDR--VREEGQLILFQNTPNRTWDCVLVNPRNSQSGFRLFQLELEADALVNF--HQYSSQ 90

Query: 113 SLPFGAQSTQRGHTELL 129
            LPF   S Q  HTE+L
Sbjct: 91  LLPFYESSPQVLHTEVL 107


>gi|52486194 phospholipase A2, group VI isoform a [Homo sapiens]
          Length = 806

 Score = 29.3 bits (64), Expect = 8.5
 Identities = 26/77 (33%), Positives = 35/77 (45%), Gaps = 11/77 (14%)

Query: 60  SDRFWVRGEGPIFFYTGNEGDVWAFA------NNSAF-VAELAAERGALLVFAEHRYYGK 112
           SDR  VR EG +  +       W         + S F + +L  E  AL+ F  H+Y  +
Sbjct: 35  SDR--VREEGQLILFQNTPNRTWDCVLVNPRNSQSGFRLFQLELEADALVNF--HQYSSQ 90

Query: 113 SLPFGAQSTQRGHTELL 129
            LPF   S Q  HTE+L
Sbjct: 91  LLPFYESSPQVLHTEVL 107


>gi|91982767 semaphorin 5B isoform 1 [Homo sapiens]
          Length = 1151

 Score = 29.3 bits (64), Expect = 8.5
 Identities = 17/47 (36%), Positives = 24/47 (51%), Gaps = 2/47 (4%)

Query: 150 GAQDAPA--IAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAG 194
           G  D PA  +  G + GG L + +R   P L  GA  A  P++ +AG
Sbjct: 17  GPPDTPAQQLRCGWTVGGWLLSLVRGLLPCLPPGARTAEGPIMVLAG 63


>gi|9966764 lysophospholipase II [Homo sapiens]
          Length = 231

 Score = 29.3 bits (64), Expect = 8.5
 Identities = 22/58 (37%), Positives = 28/58 (48%), Gaps = 3/58 (5%)

Query: 132 EQALADFAELLRALRRDLGAQDAPA--IAFGG-SYGGMLSAYLRMKYPHLVAGALAAS 186
           E  +   AE ++AL         PA  I  GG S GG LS Y  +  PH +AG +A S
Sbjct: 89  EAGIKKAAENIKALIEHEMKNGIPANRIVLGGFSQGGALSLYTALTCPHPLAGIVALS 146


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.139    0.440 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,438,294
Number of Sequences: 37866
Number of extensions: 875845
Number of successful extensions: 1563
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1541
Number of HSP's gapped (non-prelim): 13
length of query: 492
length of database: 18,247,518
effective HSP length: 106
effective length of query: 386
effective length of database: 14,233,722
effective search space: 5494216692
effective search space used: 5494216692
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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