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Search of human proteins with 62388888
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|62388888 potassium inwardly-rectifying channel J11 [Homo
sapiens]
(390 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|62388888 potassium inwardly-rectifying channel J11 [Homo sapi... 777 0.0
gi|4826802 potassium inwardly-rectifying channel J8 [Homo sapiens] 533 e-151
gi|25121970 potassium inwardly-rectifying channel subfamily J9 [... 351 7e-97
gi|4504843 potassium inwardly-rectifying channel J6 [Homo sapiens] 341 8e-94
gi|23110982 potassium inwardly-rectifying channel, subfamily J, ... 341 8e-94
gi|239758082 PREDICTED: similar to thyrotoxic periodic paralysis... 338 6e-93
gi|4504835 potassium inwardly-rectifying channel J2 [Homo sapiens] 332 4e-91
gi|24797141 potassium inwardly-rectifying channel J5 [Homo sapiens] 330 1e-90
gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens] 330 1e-90
gi|4826798 potassium inwardly-rectifying channel J4 [Homo sapiens] 328 5e-90
gi|23110984 potassium inwardly-rectifying channel J4 [Homo sapiens] 328 5e-90
gi|239757993 PREDICTED: similar to inward rectifying K+ channel ... 328 7e-90
gi|239757991 PREDICTED: similar to inward rectifying K+ channel ... 328 7e-90
gi|239751249 PREDICTED: hypothetical protein XP_002347768 [Homo ... 328 7e-90
gi|7019439 potassium inwardly-rectifying channel J14 [Homo sapiens] 312 4e-85
gi|25777635 potassium inwardly-rectifying channel J14 [Homo sapi... 312 4e-85
gi|24497471 potassium inwardly-rectifying channel J1 isoform b [... 300 2e-81
gi|24497467 potassium inwardly-rectifying channel J1 isoform b [... 300 2e-81
gi|4504837 potassium inwardly-rectifying channel J1 isoform a [H... 300 2e-81
gi|148539892 potassium inwardly-rectifying channel J1 isoform b ... 300 2e-81
gi|24497473 potassium inwardly-rectifying channel J1 isoform b [... 300 2e-81
gi|25121966 potassium inwardly-rectifying channel, subfamily J, ... 258 8e-69
gi|8923823 potassium inwardly-rectifying channel J16 [Homo sapiens] 257 1e-68
gi|25777630 potassium inwardly-rectifying channel J16 [Homo sapi... 257 1e-68
gi|25777628 potassium inwardly-rectifying channel J16 [Homo sapi... 257 1e-68
gi|21361127 potassium inwardly-rectifying channel J15 [Homo sapi... 242 4e-64
gi|25777640 potassium inwardly-rectifying channel J15 [Homo sapi... 242 4e-64
gi|25777638 potassium inwardly-rectifying channel J15 [Homo sapi... 242 4e-64
gi|156119627 potassium inwardly-rectifying channel J13 [Homo sap... 161 1e-39
>gi|62388888 potassium inwardly-rectifying channel J11 [Homo
sapiens]
Length = 390
Score = 777 bits (2006), Expect = 0.0
Identities = 390/390 (100%), Positives = 390/390 (100%)
Query: 1 MLSRKGIIPEEYVLTRLAEDPAKPRYRARQRRARFVSKKGNCNVAHKNIREQGRFLQDVF 60
MLSRKGIIPEEYVLTRLAEDPAKPRYRARQRRARFVSKKGNCNVAHKNIREQGRFLQDVF
Sbjct: 1 MLSRKGIIPEEYVLTRLAEDPAKPRYRARQRRARFVSKKGNCNVAHKNIREQGRFLQDVF 60
Query: 61 TTLVDLKWPHTLLIFTMSFLCSWLLFAMAWWLIAFAHGDLAPSEGTAEPCVTSIHSFSSA 120
TTLVDLKWPHTLLIFTMSFLCSWLLFAMAWWLIAFAHGDLAPSEGTAEPCVTSIHSFSSA
Sbjct: 61 TTLVDLKWPHTLLIFTMSFLCSWLLFAMAWWLIAFAHGDLAPSEGTAEPCVTSIHSFSSA 120
Query: 121 FLFSIEVQVTIGFGGRMVTEECPLAILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAET 180
FLFSIEVQVTIGFGGRMVTEECPLAILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAET
Sbjct: 121 FLFSIEVQVTIGFGGRMVTEECPLAILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAET 180
Query: 181 LIFSKHAVIALRHGRLCFMLRVGDLRKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPM 240
LIFSKHAVIALRHGRLCFMLRVGDLRKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPM
Sbjct: 181 LIFSKHAVIALRHGRLCFMLRVGDLRKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPM 240
Query: 241 ENGVGGNSIFLVAPLIIYHVIDANSPLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQA 300
ENGVGGNSIFLVAPLIIYHVIDANSPLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQA
Sbjct: 241 ENGVGGNSIFLVAPLIIYHVIDANSPLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQA 300
Query: 301 RTSYLADEILWGQRFVPIVAEEDGRYSVDYSKFGNTVKVPTPLCTARQLDEDHSLLEALT 360
RTSYLADEILWGQRFVPIVAEEDGRYSVDYSKFGNTVKVPTPLCTARQLDEDHSLLEALT
Sbjct: 301 RTSYLADEILWGQRFVPIVAEEDGRYSVDYSKFGNTVKVPTPLCTARQLDEDHSLLEALT 360
Query: 361 LASARGPLRKRSVPMAKAKPKFSISPDSLS 390
LASARGPLRKRSVPMAKAKPKFSISPDSLS
Sbjct: 361 LASARGPLRKRSVPMAKAKPKFSISPDSLS 390
>gi|4826802 potassium inwardly-rectifying channel J8 [Homo sapiens]
Length = 424
Score = 533 bits (1372), Expect = e-151
Identities = 273/385 (70%), Positives = 324/385 (84%), Gaps = 14/385 (3%)
Query: 1 MLSRKGIIPEEYVLTRLA-EDPAKPRYRARQRRARFVSKKGNCNVAHKNIREQGRFLQDV 59
ML+RK IIPEEYVL R+A E+ KPR R R +ARF++K G CN+AHKNIREQGRFLQD+
Sbjct: 1 MLARKSIIPEEYVLARIAAENLRKPRIRDRLPKARFIAKSGACNLAHKNIREQGRFLQDI 60
Query: 60 FTTLVDLKWPHTLLIFTMSFLCSWLLFAMAWWLIAFAHGDL---------APSEGTAEPC 110
FTTLVDLKW HTL+IFTMSFLCSWLLFA+ WWL+AFAHGD+ S + C
Sbjct: 61 FTTLVDLKWRHTLVIFTMSFLCSWLLFAIMWWLVAFAHGDIYAYMEKSGMEKSGLESTVC 120
Query: 111 VTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAILILIVQNIVGLMINAIMLGCIFMK 170
VT++ SF+SAFLFSIEVQVTIGFGGRM+TEECPLAI +LI+QNIVGL+INA+MLGCIFMK
Sbjct: 121 VTNVRSFTSAFLFSIEVQVTIGFGGRMMTEECPLAITVLILQNIVGLIINAVMLGCIFMK 180
Query: 171 TAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDLRKSMIISATIHMQVVRKTTSPEGEV 230
TAQAHRRAETLIFS+HAVIA+R+G+LCFM RVGDLRKSMIISA++ +QVV+KTT+PEGEV
Sbjct: 181 TAQAHRRAETLIFSRHAVIAVRNGKLCFMFRVGDLRKSMIISASVRIQVVKKTTTPEGEV 240
Query: 231 VPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANSPLYDLAPSDLHHHQDLEIIVILEGV 290
VP+HQ+DIP++N + N+IFLVAPLII HVID SPLYD++ +DL +QDLE+IVILEGV
Sbjct: 241 VPIHQLDIPVDNPIESNNIFLVAPLIICHVIDKRSPLYDISATDL-ANQDLEVIVILEGV 299
Query: 291 VETTGITTQARTSYLADEILWGQRFVPIVAEEDGRYSVDYSKFGNTVKVPTPLCTARQLD 350
VETTGITTQARTSY+A+EI WG RFV IV EE+G YSVDYSKFGNTVKV P C+AR+LD
Sbjct: 300 VETTGITTQARTSYIAEEIQWGHRFVSIVTEEEGVYSVDYSKFGNTVKVAAPRCSARELD 359
Query: 351 EDHS-LLEALTLA--SARGPLRKRS 372
E S L++ L + S + LRKR+
Sbjct: 360 EKPSILIQTLQKSELSHQNSLRKRN 384
>gi|25121970 potassium inwardly-rectifying channel subfamily J9
[Homo sapiens]
Length = 393
Score = 351 bits (900), Expect = 7e-97
Identities = 173/341 (50%), Positives = 239/341 (70%), Gaps = 7/341 (2%)
Query: 19 EDPAKPRYRARQRRARFVSKKGNCNVAHKNIREQGRFLQDVFTTLVDLKWPHTLLIFTMS 78
E+P PR R RQR +V K G CNV N+RE R+L D+FTTLVDL+W +LL F ++
Sbjct: 13 EEP--PRRRGRQR---YVEKDGRCNVQQGNVRETYRYLTDLFTTLVDLQWRLSLLFFVLA 67
Query: 79 FLCSWLLFAMAWWLIAFAHGDLAPSEGTA-EPCVTSIHSFSSAFLFSIEVQVTIGFGGRM 137
+ +WL F WWLIA+ GDL E TA PCV +++ F +AFLFSIE + TIG+G R+
Sbjct: 68 YALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETTIGYGHRV 127
Query: 138 VTEECPLAILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLC 197
+T++CP I++L++Q I+G M+NA M+GC+F+K +Q ++RA TL+FS HAV++LR GRLC
Sbjct: 128 ITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLC 187
Query: 198 FMLRVGDLRKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLII 257
M RVGDLR S I+ A+I +++R + EGE +PLHQ D+ + G + +FLV+PL+I
Sbjct: 188 LMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVI 247
Query: 258 YHVIDANSPLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVP 317
H IDA SP ++ + L D EI+VILEG+VE TG+T QAR+SYL DE+LWG RF
Sbjct: 248 SHEIDAASPFWEASRRAL-ERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTS 306
Query: 318 IVAEEDGRYSVDYSKFGNTVKVPTPLCTARQLDEDHSLLEA 358
++ EDG Y VDY+ F T +VPTP C+AR+L E + L+A
Sbjct: 307 VLTLEDGFYEVDYASFHETFEVPTPSCSARELAEAAARLDA 347
>gi|4504843 potassium inwardly-rectifying channel J6 [Homo sapiens]
Length = 423
Score = 341 bits (874), Expect = 8e-94
Identities = 162/328 (49%), Positives = 234/328 (71%), Gaps = 2/328 (0%)
Query: 25 RYRARQRRARFVSKKGNCNVAHKNIREQGRFLQDVFTTLVDLKWPHTLLIFTMSFLCSWL 84
R R +++ R+V K G CNV H N+RE R+L D+FTTLVDLKW LLIF M + +WL
Sbjct: 46 RDRTKRKIQRYVRKDGKCNVHHGNVRETYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWL 105
Query: 85 LFAMAWWLIAFAHGDLAPSEGTA-EPCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECP 143
F M WWLIA+ GD+ E + PCVT+++ F SAFLFSIE + TIG+G R++T++CP
Sbjct: 106 FFGMIWWLIAYIRGDMDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCP 165
Query: 144 LAILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVG 203
I++L++Q+++G ++NA M+GC+F+K +Q +RAETL+FS HAVI++R G+LC M RVG
Sbjct: 166 EGIILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVG 225
Query: 204 DLRKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDA 263
DLR S I+ A+I ++++ + EGE +PL+Q DI + G + +FLV+PLII H I+
Sbjct: 226 DLRNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQ 285
Query: 264 NSPLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAEED 323
SP ++++ + L ++LEI+VILEG+VE TG+T QAR+SY+ EILWG RF P++ ED
Sbjct: 286 QSPFWEISKAQL-PKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLTLED 344
Query: 324 GRYSVDYSKFGNTVKVPTPLCTARQLDE 351
G Y VDY+ F T + TP +A++L E
Sbjct: 345 GFYEVDYNSFHETYETSTPSLSAKELAE 372
>gi|23110982 potassium inwardly-rectifying channel, subfamily J,
member 12 [Homo sapiens]
Length = 433
Score = 341 bits (874), Expect = 8e-94
Identities = 171/331 (51%), Positives = 236/331 (71%), Gaps = 4/331 (1%)
Query: 29 RQRRARFVSKKGNCNVAHKNIREQG-RFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFA 87
R+ R RFV K G CN+ N+ E+ R+L D+FTT VD++W + LLIF+++FL SWLLF
Sbjct: 40 RRCRNRFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFG 99
Query: 88 MAWWLIAFAHGDLAPSEGTAE-PCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAI 146
+ +W+IA AHGDL P+EG PCV +H F +AFLFSIE Q TIG+G R VTEECP+A+
Sbjct: 100 IIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAV 159
Query: 147 LILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDLR 206
+++ Q+IVG +I++ M+G I K A+ +RA+TL+FS +AV+ALR G+LC M RVG+LR
Sbjct: 160 FMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLR 219
Query: 207 KSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANSP 266
KS I+ A + Q+++ + EGE +PL Q+DI + G + IFLV+P+ I H ID SP
Sbjct: 220 KSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASP 279
Query: 267 LYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAEEDGRY 326
L+ ++ DL D EI+VILEG+VE T +TTQAR+SYLA+EILWG RF P++ EE +Y
Sbjct: 280 LFGISRQDL-ETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQY 338
Query: 327 SVDYSKFGNTVKVP-TPLCTARQLDEDHSLL 356
+DYS F T +VP TP C+A+ L E+ LL
Sbjct: 339 KIDYSHFHKTYEVPSTPRCSAKDLVENKFLL 369
>gi|239758082 PREDICTED: similar to thyrotoxic periodic paralysis
susceptibility ion channel [Homo sapiens]
Length = 433
Score = 338 bits (866), Expect = 6e-93
Identities = 171/331 (51%), Positives = 235/331 (70%), Gaps = 4/331 (1%)
Query: 29 RQRRARFVSKKGNCNVAHKNIREQG-RFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFA 87
R+ R RFV K G CN+A N+ E+ R+L D+FTT VD++W + LLIF+++FL SWLLF
Sbjct: 40 RRCRNRFVKKNGQCNIAFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFG 99
Query: 88 MAWWLIAFAHGDLAPSEGTAE-PCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAI 146
+ +W+IA AHGDL P+EG PCV +H F +AFLFSIE Q TIG+G R VTEEC +A+
Sbjct: 100 VIFWVIAVAHGDLEPAEGHGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVAV 159
Query: 147 LILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDLR 206
+++ Q+IVG +I++ M+G I K A+ +RA TL+FS +AV+ALR G+LC M RVG+LR
Sbjct: 160 FMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAHTLLFSHNAVVALRDGKLCLMWRVGNLR 219
Query: 207 KSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANSP 266
KS I+ A + Q+++ + EGE +PL Q+DI + G + IFLV+P+ I H ID SP
Sbjct: 220 KSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASP 279
Query: 267 LYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAEEDGRY 326
L+ ++ DL D EI+VILEG+VE T +TTQAR+SYLA+EILWG RF P++ EE +Y
Sbjct: 280 LFGISRQDL-ETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQY 338
Query: 327 SVDYSKFGNTVKVP-TPLCTARQLDEDHSLL 356
+DYS F T +VP TP C+A+ L E+ LL
Sbjct: 339 KIDYSHFHKTYEVPSTPRCSAKDLVENKFLL 369
>gi|4504835 potassium inwardly-rectifying channel J2 [Homo sapiens]
Length = 427
Score = 332 bits (851), Expect = 4e-91
Identities = 171/338 (50%), Positives = 240/338 (71%), Gaps = 7/338 (2%)
Query: 23 KPRYRARQR-RARFVSKKGNCNVAHKNIREQG-RFLQDVFTTLVDLKWPHTLLIFTMSFL 80
K + RQ+ R+RFV K G+CNV N+ E+G R+L D+FTT VD++W L+IF ++F+
Sbjct: 34 KSKVHTRQQCRSRFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFV 93
Query: 81 CSWLLFAMAWWLIAFAHGDL-APSEGTAEPCVTSIHSFSSAFLFSIEVQVTIGFGGRMVT 139
SWL F +WLIA HGDL A EG A CV+ ++SF++AFLFSIE Q TIG+G R VT
Sbjct: 94 LSWLFFGCVFWLIALLHGDLDASKEGKA--CVSEVNSFTAAFLFSIETQTTIGYGFRCVT 151
Query: 140 EECPLAILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFM 199
+ECP+A+ +++ Q+IVG +I+A ++G + K A+ +R ETL+FS +AVIA+R G+LC M
Sbjct: 152 DECPIAVFMVVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLM 211
Query: 200 LRVGDLRKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYH 259
RVG+LRKS ++ A + Q+++ + EGE +PL Q+DI + G + IFLV+P+ I H
Sbjct: 212 WRVGNLRKSHLVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVH 271
Query: 260 VIDANSPLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIV 319
ID +SPLYDL+ D+ + D EI+VILEG+VE T +TTQ R+SYLA+EILWG R+ P++
Sbjct: 272 EIDEDSPLYDLSKQDI-DNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVL 330
Query: 320 AEEDGRYSVDYSKFGNTVKVP-TPLCTARQLDEDHSLL 356
EE Y VDYS+F T +VP TPLC+AR L E +L
Sbjct: 331 FEEKHYYKVDYSRFHKTYEVPNTPLCSARDLAEKKYIL 368
>gi|24797141 potassium inwardly-rectifying channel J5 [Homo sapiens]
Length = 419
Score = 330 bits (847), Expect = 1e-90
Identities = 160/337 (47%), Positives = 232/337 (68%), Gaps = 4/337 (1%)
Query: 17 LAEDPAKPRYRARQRRARFVSKKGNCNVAHKNIREQGRFLQDVFTTLVDLKWPHTLLIFT 76
+A D + ++ R R++ K G CNV H N++E R+L D+FTTLVDLKW LL+FT
Sbjct: 35 IATDRTRLLAEGKKPRQRYMEKSGKCNVHHGNVQETYRYLSDLFTTLVDLKWRFNLLVFT 94
Query: 77 MSFLCSWLLFAMAWWLIAFAHGDLAPSEGTAE--PCVTSIHSFSSAFLFSIEVQVTIGFG 134
M + +WL F WWLIA+ GDL G E PCV ++ F SAFLFSIE + TIG+G
Sbjct: 95 MVYTVTWLFFGFIWWLIAYIRGDL-DHVGDQEWIPCVENLSGFVSAFLFSIETETTIGYG 153
Query: 135 GRMVTEECPLAILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHG 194
R++TE+CP I++L+VQ I+G ++NA M+GC+F+K +Q +RAETL+FS +AVI++R
Sbjct: 154 FRVITEKCPEGIILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDE 213
Query: 195 RLCFMLRVGDLRKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAP 254
+LC M RVGDLR S I+ A+I ++++ + EGE +PL+Q DI + G + +FLV+P
Sbjct: 214 KLCLMFRVGDLRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSP 273
Query: 255 LIIYHVIDANSPLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQR 314
LII H I+ SP ++++ + L H ++ E++VILEG+VE TG+T QAR+SY+ E+LWG R
Sbjct: 274 LIISHEINQKSPFWEMSQAQL-HQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHR 332
Query: 315 FVPIVAEEDGRYSVDYSKFGNTVKVPTPLCTARQLDE 351
F P++ E G Y VDY+ F +T + TP C A++L E
Sbjct: 333 FTPVLTLEKGFYEVDYNTFHDTYETNTPSCCAKELAE 369
>gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens]
Length = 501
Score = 330 bits (846), Expect = 1e-90
Identities = 156/325 (48%), Positives = 230/325 (70%), Gaps = 3/325 (0%)
Query: 29 RQRRARFVSKKGNCNVAHKNI-REQGRFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFA 87
+++R RFV K G CNV H N+ E R+L D+FTTLVDLKW L IF +++ +WL A
Sbjct: 40 KKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMA 99
Query: 88 MAWWLIAFAHGDLAPSE-GTAEPCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAI 146
WW+IA+ GDL + G PCV ++++F SAFLF IE + TIG+G R +T++CP I
Sbjct: 100 SMWWVIAYTRGDLNKAHVGNYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGI 159
Query: 147 LILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDLR 206
++ + Q+I+G +++A ++GC+F+K +Q +RAETL+FS+HAVI++R G+L M RVG+LR
Sbjct: 160 ILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNLR 219
Query: 207 KSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANSP 266
S ++SA I ++++ +PEGE +PL Q+++ + G + +FLV+PL I HVIDA SP
Sbjct: 220 NSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKSP 279
Query: 267 LYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAEEDGRY 326
YDL+ + Q EI+VILEG+VETTG+T QARTSY DE+LWG RF P+++ E+G +
Sbjct: 280 FYDLSQRSMQTEQ-FEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISLEEGFF 338
Query: 327 SVDYSKFGNTVKVPTPLCTARQLDE 351
VDYS+F T +VPTP + ++ +E
Sbjct: 339 KVDYSQFHATFEVPTPPYSVKEQEE 363
>gi|4826798 potassium inwardly-rectifying channel J4 [Homo sapiens]
Length = 445
Score = 328 bits (841), Expect = 5e-90
Identities = 167/342 (48%), Positives = 229/342 (66%), Gaps = 20/342 (5%)
Query: 29 RQRRARFVSKKGNCNVAHKNIREQG-RFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFA 87
R+RR RFV K G CNV N+ + R++ D+FTT VD +W + L+IF+ +FL SWL F
Sbjct: 15 RKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFG 74
Query: 88 MAWWLIAFAHGDLAPSEGTA-----------------EPCVTSIHSFSSAFLFSIEVQVT 130
+ +W IAF HGDL S G +PC+ ++ F AFLFS+E Q T
Sbjct: 75 LLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTT 134
Query: 131 IGFGGRMVTEECPLAILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIA 190
IG+G R VTEECPLA++ ++VQ+IVG +I++ M+G I K A+ +RA+TL+FS HAVI+
Sbjct: 135 IGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVIS 194
Query: 191 LRHGRLCFMLRVGDLRKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIF 250
+R G+LC M RVG+LRKS I+ A + Q+++ + EGE +PL Q D+ + +G + IF
Sbjct: 195 VRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIF 254
Query: 251 LVAPLIIYHVIDANSPLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEIL 310
LV+P+II H ID +SPLY + +L +D EI+VILEG+VE T +TTQAR+SYLA EIL
Sbjct: 255 LVSPIIIVHEIDEDSPLYGMGKEEL-ESEDFEIVVILEGMVEATAMTTQARSSYLASEIL 313
Query: 311 WGQRFVPIVAEEDGRYSVDYSKFGNTVKVP-TPLCTARQLDE 351
WG RF P+V EE Y VDYS+F T +V TP C+AR+L E
Sbjct: 314 WGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQE 355
>gi|23110984 potassium inwardly-rectifying channel J4 [Homo sapiens]
Length = 445
Score = 328 bits (841), Expect = 5e-90
Identities = 167/342 (48%), Positives = 229/342 (66%), Gaps = 20/342 (5%)
Query: 29 RQRRARFVSKKGNCNVAHKNIREQG-RFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFA 87
R+RR RFV K G CNV N+ + R++ D+FTT VD +W + L+IF+ +FL SWL F
Sbjct: 15 RKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFG 74
Query: 88 MAWWLIAFAHGDLAPSEGTA-----------------EPCVTSIHSFSSAFLFSIEVQVT 130
+ +W IAF HGDL S G +PC+ ++ F AFLFS+E Q T
Sbjct: 75 LLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTT 134
Query: 131 IGFGGRMVTEECPLAILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIA 190
IG+G R VTEECPLA++ ++VQ+IVG +I++ M+G I K A+ +RA+TL+FS HAVI+
Sbjct: 135 IGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVIS 194
Query: 191 LRHGRLCFMLRVGDLRKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIF 250
+R G+LC M RVG+LRKS I+ A + Q+++ + EGE +PL Q D+ + +G + IF
Sbjct: 195 VRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIF 254
Query: 251 LVAPLIIYHVIDANSPLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEIL 310
LV+P+II H ID +SPLY + +L +D EI+VILEG+VE T +TTQAR+SYLA EIL
Sbjct: 255 LVSPIIIVHEIDEDSPLYGMGKEEL-ESEDFEIVVILEGMVEATAMTTQARSSYLASEIL 313
Query: 311 WGQRFVPIVAEEDGRYSVDYSKFGNTVKVP-TPLCTARQLDE 351
WG RF P+V EE Y VDYS+F T +V TP C+AR+L E
Sbjct: 314 WGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQE 355
>gi|239757993 PREDICTED: similar to inward rectifying K+ channel
negative regulator Kir2.2v isoform 1 [Homo sapiens]
Length = 432
Score = 328 bits (840), Expect = 7e-90
Identities = 165/331 (49%), Positives = 233/331 (70%), Gaps = 5/331 (1%)
Query: 29 RQRRARFVSKKGNCNVAHKNIREQG-RFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFA 87
R+ RFV K G CN+ N+ E+ R+L D+FTT VD++W + LLIF+++FL SWLLF
Sbjct: 40 RRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFG 99
Query: 88 MAWWLIAFAHGDLAPSEGTAE-PCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAI 146
+ +W+IA AHGDL P+EG PCV +H F +AFLFSI+ Q TI +G R VTEECP+A+
Sbjct: 100 VIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAV 159
Query: 147 LILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDLR 206
+++ Q+IVG +IN+ M+G I K + +RA+TL+FS +AV+ALR G+LCFM RVG+LR
Sbjct: 160 FMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLR 219
Query: 207 KSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANSP 266
KS I+ A + Q+++ + EGE +PL Q+DI + G + FLV+P+ I H ID SP
Sbjct: 220 KSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASP 279
Query: 267 LYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAEEDGRY 326
L+ ++ DL D EI++ILEG+VE T +TTQAR+SYLA+EILWG RF P++ E++ +Y
Sbjct: 280 LFGISRQDL-QMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPVLFEKN-QY 337
Query: 327 SVDYSKFGNTVKVP-TPLCTARQLDEDHSLL 356
+DY F T +VP TP C+A+ L E+ LL
Sbjct: 338 KIDYLHFHKTYEVPSTPRCSAKDLVENKFLL 368
>gi|239757991 PREDICTED: similar to inward rectifying K+ channel
negative regulator Kir2.2v isoform 2 [Homo sapiens]
Length = 534
Score = 328 bits (840), Expect = 7e-90
Identities = 165/331 (49%), Positives = 233/331 (70%), Gaps = 5/331 (1%)
Query: 29 RQRRARFVSKKGNCNVAHKNIREQG-RFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFA 87
R+ RFV K G CN+ N+ E+ R+L D+FTT VD++W + LLIF+++FL SWLLF
Sbjct: 142 RRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFG 201
Query: 88 MAWWLIAFAHGDLAPSEGTAE-PCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAI 146
+ +W+IA AHGDL P+EG PCV +H F +AFLFSI+ Q TI +G R VTEECP+A+
Sbjct: 202 VIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAV 261
Query: 147 LILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDLR 206
+++ Q+IVG +IN+ M+G I K + +RA+TL+FS +AV+ALR G+LCFM RVG+LR
Sbjct: 262 FMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLR 321
Query: 207 KSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANSP 266
KS I+ A + Q+++ + EGE +PL Q+DI + G + FLV+P+ I H ID SP
Sbjct: 322 KSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASP 381
Query: 267 LYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAEEDGRY 326
L+ ++ DL D EI++ILEG+VE T +TTQAR+SYLA+EILWG RF P++ E++ +Y
Sbjct: 382 LFGISRQDL-QMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPVLFEKN-QY 439
Query: 327 SVDYSKFGNTVKVP-TPLCTARQLDEDHSLL 356
+DY F T +VP TP C+A+ L E+ LL
Sbjct: 440 KIDYLHFHKTYEVPSTPRCSAKDLVENKFLL 470
>gi|239751249 PREDICTED: hypothetical protein XP_002347768 [Homo
sapiens]
Length = 432
Score = 328 bits (840), Expect = 7e-90
Identities = 165/331 (49%), Positives = 233/331 (70%), Gaps = 5/331 (1%)
Query: 29 RQRRARFVSKKGNCNVAHKNIREQG-RFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFA 87
R+ RFV K G CN+ N+ E+ R+L D+FTT VD++W + LLIF+++FL SWLLF
Sbjct: 40 RRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFG 99
Query: 88 MAWWLIAFAHGDLAPSEGTAE-PCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAI 146
+ +W+IA AHGDL P+EG PCV +H F +AFLFSI+ Q TI +G R VTEECP+A+
Sbjct: 100 VIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAV 159
Query: 147 LILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDLR 206
+++ Q+IVG +IN+ M+G I K + +RA+TL+FS +AV+ALR G+LCFM RVG+LR
Sbjct: 160 FMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLR 219
Query: 207 KSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANSP 266
KS I+ A + Q+++ + EGE +PL Q+DI + G + FLV+P+ I H ID SP
Sbjct: 220 KSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASP 279
Query: 267 LYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAEEDGRY 326
L+ ++ DL D EI++ILEG+VE T +TTQAR+SYLA+EILWG RF P++ E++ +Y
Sbjct: 280 LFGISRQDL-QMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPVLFEKN-QY 337
Query: 327 SVDYSKFGNTVKVP-TPLCTARQLDEDHSLL 356
+DY F T +VP TP C+A+ L E+ LL
Sbjct: 338 KIDYLHFHKTYEVPSTPRCSAKDLVENKFLL 368
>gi|7019439 potassium inwardly-rectifying channel J14 [Homo sapiens]
Length = 436
Score = 312 bits (799), Expect = 4e-85
Identities = 158/333 (47%), Positives = 227/333 (68%), Gaps = 4/333 (1%)
Query: 21 PAKPRYRARQRRARFVSKKGNCNVAHKNIREQG-RFLQDVFTTLVDLKWPHTLLIFTMSF 79
PA + +RR RFV K G+CNV N+ QG R+L D+FTT VD++W L+F+ SF
Sbjct: 38 PAPVQSPVGRRRGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSF 97
Query: 80 LCSWLLFAMAWWLIAFAHGDLAPSEGTAEPCVTSIHSFSSAFLFSIEVQVTIGFGGRMVT 139
L SWLLF +A+WLIA HGDLA A PC + + SF +AFLF++E Q +IG+G R VT
Sbjct: 98 LASWLLFGLAFWLIASLHGDLAAPPPPA-PCFSHVASFLAAFLFALETQTSIGYGVRSVT 156
Query: 140 EECPLAILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFM 199
EECP A+ +++Q I G +++A ++G + K A+ +R ETL+FS++AV+ALR RLC M
Sbjct: 157 EECPAAVAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLM 216
Query: 200 LRVGDLRKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYH 259
RVG+LR+S ++ A + Q+++ +PEGE +PL D+ + G + IFLV+P+ I H
Sbjct: 217 WRVGNLRRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVH 276
Query: 260 VIDANSPLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIV 319
ID+ SPLY+L ++L D E++VILEG+VE T +TTQ R+SYL E+LWG RF P++
Sbjct: 277 EIDSASPLYELGRAEL-ARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVL 335
Query: 320 AEEDGRYSVDYSKFGNTVKVP-TPLCTARQLDE 351
+ +Y VDY F T +VP TP+C+A++LDE
Sbjct: 336 FQRGSQYEVDYRHFHRTYEVPGTPVCSAKELDE 368
>gi|25777635 potassium inwardly-rectifying channel J14 [Homo
sapiens]
Length = 436
Score = 312 bits (799), Expect = 4e-85
Identities = 158/333 (47%), Positives = 227/333 (68%), Gaps = 4/333 (1%)
Query: 21 PAKPRYRARQRRARFVSKKGNCNVAHKNIREQG-RFLQDVFTTLVDLKWPHTLLIFTMSF 79
PA + +RR RFV K G+CNV N+ QG R+L D+FTT VD++W L+F+ SF
Sbjct: 38 PAPVQSPVGRRRGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSF 97
Query: 80 LCSWLLFAMAWWLIAFAHGDLAPSEGTAEPCVTSIHSFSSAFLFSIEVQVTIGFGGRMVT 139
L SWLLF +A+WLIA HGDLA A PC + + SF +AFLF++E Q +IG+G R VT
Sbjct: 98 LASWLLFGLAFWLIASLHGDLAAPPPPA-PCFSHVASFLAAFLFALETQTSIGYGVRSVT 156
Query: 140 EECPLAILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFM 199
EECP A+ +++Q I G +++A ++G + K A+ +R ETL+FS++AV+ALR RLC M
Sbjct: 157 EECPAAVAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLM 216
Query: 200 LRVGDLRKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYH 259
RVG+LR+S ++ A + Q+++ +PEGE +PL D+ + G + IFLV+P+ I H
Sbjct: 217 WRVGNLRRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVH 276
Query: 260 VIDANSPLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIV 319
ID+ SPLY+L ++L D E++VILEG+VE T +TTQ R+SYL E+LWG RF P++
Sbjct: 277 EIDSASPLYELGRAEL-ARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVL 335
Query: 320 AEEDGRYSVDYSKFGNTVKVP-TPLCTARQLDE 351
+ +Y VDY F T +VP TP+C+A++LDE
Sbjct: 336 FQRGSQYEVDYRHFHRTYEVPGTPVCSAKELDE 368
>gi|24497471 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 300 bits (767), Expect = 2e-81
Identities = 147/320 (45%), Positives = 219/320 (68%), Gaps = 6/320 (1%)
Query: 30 QRRARFVSKKGNCNVAHKNIREQGRFL--QDVFTTLVDLKWPHTLLIFTMSFLCSWLLFA 87
++RAR VSK G CN+ N+ Q RF+ D++TT++DLKW + + IF +FL SW F
Sbjct: 18 RQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFG 77
Query: 88 MAWWLIAFAHGDLAPSEGTAE--PCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLA 145
+ W+ +A+ H DL +A PCV +I+ +SAFLFS+E QVTIG+G R VTE+C A
Sbjct: 78 LLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCATA 137
Query: 146 ILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDL 205
I +LI Q+I+G++IN+ M G I K ++ +RA+T+ FSK+AVI+ R G+LC ++RV +L
Sbjct: 138 IFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANL 197
Query: 206 RKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANS 265
RKS++I + I+ ++++ T +PEGE + L Q++I G ++F ++PL IYHVID NS
Sbjct: 198 RKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVIDHNS 257
Query: 266 PLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAE-EDG 324
P + +A L QD E++V L+G VE+T T Q RTSY+ +E+LWG RF PIV++ ++G
Sbjct: 258 PFFHMAAETL-LQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEG 316
Query: 325 RYSVDYSKFGNTVKVPTPLC 344
+Y VD+ F TV+V TP C
Sbjct: 317 KYRVDFHNFSKTVEVETPHC 336
>gi|24497467 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 300 bits (767), Expect = 2e-81
Identities = 147/320 (45%), Positives = 219/320 (68%), Gaps = 6/320 (1%)
Query: 30 QRRARFVSKKGNCNVAHKNIREQGRFL--QDVFTTLVDLKWPHTLLIFTMSFLCSWLLFA 87
++RAR VSK G CN+ N+ Q RF+ D++TT++DLKW + + IF +FL SW F
Sbjct: 18 RQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFG 77
Query: 88 MAWWLIAFAHGDLAPSEGTAE--PCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLA 145
+ W+ +A+ H DL +A PCV +I+ +SAFLFS+E QVTIG+G R VTE+C A
Sbjct: 78 LLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCATA 137
Query: 146 ILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDL 205
I +LI Q+I+G++IN+ M G I K ++ +RA+T+ FSK+AVI+ R G+LC ++RV +L
Sbjct: 138 IFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANL 197
Query: 206 RKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANS 265
RKS++I + I+ ++++ T +PEGE + L Q++I G ++F ++PL IYHVID NS
Sbjct: 198 RKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVIDHNS 257
Query: 266 PLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAE-EDG 324
P + +A L QD E++V L+G VE+T T Q RTSY+ +E+LWG RF PIV++ ++G
Sbjct: 258 PFFHMAAETL-LQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEG 316
Query: 325 RYSVDYSKFGNTVKVPTPLC 344
+Y VD+ F TV+V TP C
Sbjct: 317 KYRVDFHNFSKTVEVETPHC 336
>gi|4504837 potassium inwardly-rectifying channel J1 isoform a [Homo
sapiens]
Length = 391
Score = 300 bits (767), Expect = 2e-81
Identities = 147/320 (45%), Positives = 219/320 (68%), Gaps = 6/320 (1%)
Query: 30 QRRARFVSKKGNCNVAHKNIREQGRFL--QDVFTTLVDLKWPHTLLIFTMSFLCSWLLFA 87
++RAR VSK G CN+ N+ Q RF+ D++TT++DLKW + + IF +FL SW F
Sbjct: 37 RQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFG 96
Query: 88 MAWWLIAFAHGDLAPSEGTAE--PCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLA 145
+ W+ +A+ H DL +A PCV +I+ +SAFLFS+E QVTIG+G R VTE+C A
Sbjct: 97 LLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCATA 156
Query: 146 ILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDL 205
I +LI Q+I+G++IN+ M G I K ++ +RA+T+ FSK+AVI+ R G+LC ++RV +L
Sbjct: 157 IFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANL 216
Query: 206 RKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANS 265
RKS++I + I+ ++++ T +PEGE + L Q++I G ++F ++PL IYHVID NS
Sbjct: 217 RKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVIDHNS 276
Query: 266 PLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAE-EDG 324
P + +A L QD E++V L+G VE+T T Q RTSY+ +E+LWG RF PIV++ ++G
Sbjct: 277 PFFHMAAETL-LQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEG 335
Query: 325 RYSVDYSKFGNTVKVPTPLC 344
+Y VD+ F TV+V TP C
Sbjct: 336 KYRVDFHNFSKTVEVETPHC 355
>gi|148539892 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 300 bits (767), Expect = 2e-81
Identities = 147/320 (45%), Positives = 219/320 (68%), Gaps = 6/320 (1%)
Query: 30 QRRARFVSKKGNCNVAHKNIREQGRFL--QDVFTTLVDLKWPHTLLIFTMSFLCSWLLFA 87
++RAR VSK G CN+ N+ Q RF+ D++TT++DLKW + + IF +FL SW F
Sbjct: 18 RQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFG 77
Query: 88 MAWWLIAFAHGDLAPSEGTAE--PCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLA 145
+ W+ +A+ H DL +A PCV +I+ +SAFLFS+E QVTIG+G R VTE+C A
Sbjct: 78 LLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCATA 137
Query: 146 ILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDL 205
I +LI Q+I+G++IN+ M G I K ++ +RA+T+ FSK+AVI+ R G+LC ++RV +L
Sbjct: 138 IFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANL 197
Query: 206 RKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANS 265
RKS++I + I+ ++++ T +PEGE + L Q++I G ++F ++PL IYHVID NS
Sbjct: 198 RKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVIDHNS 257
Query: 266 PLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAE-EDG 324
P + +A L QD E++V L+G VE+T T Q RTSY+ +E+LWG RF PIV++ ++G
Sbjct: 258 PFFHMAAETL-LQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEG 316
Query: 325 RYSVDYSKFGNTVKVPTPLC 344
+Y VD+ F TV+V TP C
Sbjct: 317 KYRVDFHNFSKTVEVETPHC 336
>gi|24497473 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 300 bits (767), Expect = 2e-81
Identities = 147/320 (45%), Positives = 219/320 (68%), Gaps = 6/320 (1%)
Query: 30 QRRARFVSKKGNCNVAHKNIREQGRFL--QDVFTTLVDLKWPHTLLIFTMSFLCSWLLFA 87
++RAR VSK G CN+ N+ Q RF+ D++TT++DLKW + + IF +FL SW F
Sbjct: 18 RQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFG 77
Query: 88 MAWWLIAFAHGDLAPSEGTAE--PCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLA 145
+ W+ +A+ H DL +A PCV +I+ +SAFLFS+E QVTIG+G R VTE+C A
Sbjct: 78 LLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCATA 137
Query: 146 ILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDL 205
I +LI Q+I+G++IN+ M G I K ++ +RA+T+ FSK+AVI+ R G+LC ++RV +L
Sbjct: 138 IFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANL 197
Query: 206 RKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANS 265
RKS++I + I+ ++++ T +PEGE + L Q++I G ++F ++PL IYHVID NS
Sbjct: 198 RKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVIDHNS 257
Query: 266 PLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAE-EDG 324
P + +A L QD E++V L+G VE+T T Q RTSY+ +E+LWG RF PIV++ ++G
Sbjct: 258 PFFHMAAETL-LQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEG 316
Query: 325 RYSVDYSKFGNTVKVPTPLC 344
+Y VD+ F TV+V TP C
Sbjct: 317 KYRVDFHNFSKTVEVETPHC 336
>gi|25121966 potassium inwardly-rectifying channel, subfamily J,
member 10 [Homo sapiens]
Length = 379
Score = 258 bits (658), Expect = 8e-69
Identities = 129/316 (40%), Positives = 201/316 (63%), Gaps = 6/316 (1%)
Query: 31 RRARFVSKKGNCNVAHKNIREQG-RFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFAMA 89
RR R ++K G NV ++I ++ +L+D++TT +D++W + LL+F+ +F +W LF +
Sbjct: 26 RRRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWFLFGVV 85
Query: 90 WWLIAFAHGDLAPSEGTAE--PCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAIL 147
W+L+A AHGDL + A PCV +H+ + AFLFS+E Q TIG+G R ++EECPLAI+
Sbjct: 86 WYLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEECPLAIV 145
Query: 148 ILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDLRK 207
+LI Q ++ ++ + G K A+ +RAET+ FS+HAV+A +G+ C M+RV ++RK
Sbjct: 146 LLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIRVANMRK 205
Query: 208 SMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANSPL 267
S++I + ++++ + EGE + L+QV++ + +S FL+ PL YHV+D SPL
Sbjct: 206 SLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYHVVDETSPL 265
Query: 268 YDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVA-EEDGRY 326
DL D E+++IL G VE+T T Q RTSYL +EILWG F P ++ G+Y
Sbjct: 266 KDLPLRS--GEGDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLSASGKY 323
Query: 327 SVDYSKFGNTVKVPTP 342
D+S F VKV +P
Sbjct: 324 IADFSLFDQVVKVASP 339
>gi|8923823 potassium inwardly-rectifying channel J16 [Homo sapiens]
Length = 418
Score = 257 bits (657), Expect = 1e-68
Identities = 136/323 (42%), Positives = 204/323 (63%), Gaps = 8/323 (2%)
Query: 29 RQRRARFVSKKGNCNVAHKNI-REQGRFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFA 87
R+ R R + K G+CNV K+I E G ++ D+FTTLVD KW H +IF++S++ SWL+F
Sbjct: 30 RRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFG 89
Query: 88 MAWWLIAFAHGDLAPSEGTAEPCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAIL 147
+WLIAF HGDL ++ PCV ++HSF+ AFLFS+E Q TIG+G R VTEEC +A+L
Sbjct: 90 SVFWLIAFHHGDLL-NDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVL 148
Query: 148 ILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDLRK 207
++I+Q+I+ +IN ++G K A A +RA+T+ FS A+I +R G+LC M R+GD R
Sbjct: 149 MVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRP 208
Query: 208 SMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANSPL 267
+ ++ T+ Q++R T EG + + D+ + N + I LV P+ I H ID SPL
Sbjct: 209 NHVVEGTVRAQLLRYTEDSEGRMTMAFK-DLKLVN----DQIILVTPVTIVHEIDHESPL 263
Query: 268 YDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAEEDGRYS 327
Y L + + EI+V ++TG + Q+R+SY+ EILWG RF ++ + Y
Sbjct: 264 YALDRKAV-AKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRKYYK 322
Query: 328 VDYSKFGNTVKVPTPLCTARQLD 350
V+ +F +V+V P C+A+QLD
Sbjct: 323 VNCLQFEGSVEVYAPFCSAKQLD 345
>gi|25777630 potassium inwardly-rectifying channel J16 [Homo
sapiens]
Length = 418
Score = 257 bits (657), Expect = 1e-68
Identities = 136/323 (42%), Positives = 204/323 (63%), Gaps = 8/323 (2%)
Query: 29 RQRRARFVSKKGNCNVAHKNI-REQGRFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFA 87
R+ R R + K G+CNV K+I E G ++ D+FTTLVD KW H +IF++S++ SWL+F
Sbjct: 30 RRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFG 89
Query: 88 MAWWLIAFAHGDLAPSEGTAEPCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAIL 147
+WLIAF HGDL ++ PCV ++HSF+ AFLFS+E Q TIG+G R VTEEC +A+L
Sbjct: 90 SVFWLIAFHHGDLL-NDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVL 148
Query: 148 ILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDLRK 207
++I+Q+I+ +IN ++G K A A +RA+T+ FS A+I +R G+LC M R+GD R
Sbjct: 149 MVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRP 208
Query: 208 SMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANSPL 267
+ ++ T+ Q++R T EG + + D+ + N + I LV P+ I H ID SPL
Sbjct: 209 NHVVEGTVRAQLLRYTEDSEGRMTMAFK-DLKLVN----DQIILVTPVTIVHEIDHESPL 263
Query: 268 YDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAEEDGRYS 327
Y L + + EI+V ++TG + Q+R+SY+ EILWG RF ++ + Y
Sbjct: 264 YALDRKAV-AKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRKYYK 322
Query: 328 VDYSKFGNTVKVPTPLCTARQLD 350
V+ +F +V+V P C+A+QLD
Sbjct: 323 VNCLQFEGSVEVYAPFCSAKQLD 345
>gi|25777628 potassium inwardly-rectifying channel J16 [Homo
sapiens]
Length = 418
Score = 257 bits (657), Expect = 1e-68
Identities = 136/323 (42%), Positives = 204/323 (63%), Gaps = 8/323 (2%)
Query: 29 RQRRARFVSKKGNCNVAHKNI-REQGRFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFA 87
R+ R R + K G+CNV K+I E G ++ D+FTTLVD KW H +IF++S++ SWL+F
Sbjct: 30 RRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFG 89
Query: 88 MAWWLIAFAHGDLAPSEGTAEPCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAIL 147
+WLIAF HGDL ++ PCV ++HSF+ AFLFS+E Q TIG+G R VTEEC +A+L
Sbjct: 90 SVFWLIAFHHGDLL-NDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVL 148
Query: 148 ILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDLRK 207
++I+Q+I+ +IN ++G K A A +RA+T+ FS A+I +R G+LC M R+GD R
Sbjct: 149 MVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRP 208
Query: 208 SMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANSPL 267
+ ++ T+ Q++R T EG + + D+ + N + I LV P+ I H ID SPL
Sbjct: 209 NHVVEGTVRAQLLRYTEDSEGRMTMAFK-DLKLVN----DQIILVTPVTIVHEIDHESPL 263
Query: 268 YDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAEEDGRYS 327
Y L + + EI+V ++TG + Q+R+SY+ EILWG RF ++ + Y
Sbjct: 264 YALDRKAV-AKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRKYYK 322
Query: 328 VDYSKFGNTVKVPTPLCTARQLD 350
V+ +F +V+V P C+A+QLD
Sbjct: 323 VNCLQFEGSVEVYAPFCSAKQLD 345
>gi|21361127 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 242 bits (618), Expect = 4e-64
Identities = 126/333 (37%), Positives = 201/333 (60%), Gaps = 7/333 (2%)
Query: 29 RQRRARFVSKKGNCNVAHKNIRE-QGRFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFA 87
+ R R +SK G+ NV + +LQD++TT++D+KW + L +F +F+ +W LF
Sbjct: 23 KANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFG 82
Query: 88 MAWWLIAFAHGDLAPSEGTAE--PCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLA 145
+ ++ IAF HGDL P E + PC+ + S + AFLFS+E Q TIG+G R +TEECP A
Sbjct: 83 VIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHA 142
Query: 146 ILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDL 205
I +L+ Q ++ +I + G K A+ +RAET+ FS AVI ++G+LC +++V ++
Sbjct: 143 IFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANM 202
Query: 206 RKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANS 265
RKS++I + ++++ + EGE + L+Q + S FL+ P+ YHV+D S
Sbjct: 203 RKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETS 262
Query: 266 PLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVA-EEDG 324
PL DL P +L ++ E++V+L VE+T Q+RTSY+ +EI WG FVP+V+ ++G
Sbjct: 263 PLRDLTPQNL-KEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNG 321
Query: 325 RYSVDYSKFGNTVKVPTPLCTARQLDEDHSLLE 357
+Y D+S+F K +P CT D + LE
Sbjct: 322 KYVADFSQFEQIRK--SPDCTFYCADSEKQQLE 352
>gi|25777640 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 242 bits (618), Expect = 4e-64
Identities = 126/333 (37%), Positives = 201/333 (60%), Gaps = 7/333 (2%)
Query: 29 RQRRARFVSKKGNCNVAHKNIRE-QGRFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFA 87
+ R R +SK G+ NV + +LQD++TT++D+KW + L +F +F+ +W LF
Sbjct: 23 KANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFG 82
Query: 88 MAWWLIAFAHGDLAPSEGTAE--PCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLA 145
+ ++ IAF HGDL P E + PC+ + S + AFLFS+E Q TIG+G R +TEECP A
Sbjct: 83 VIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHA 142
Query: 146 ILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDL 205
I +L+ Q ++ +I + G K A+ +RAET+ FS AVI ++G+LC +++V ++
Sbjct: 143 IFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANM 202
Query: 206 RKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANS 265
RKS++I + ++++ + EGE + L+Q + S FL+ P+ YHV+D S
Sbjct: 203 RKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETS 262
Query: 266 PLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVA-EEDG 324
PL DL P +L ++ E++V+L VE+T Q+RTSY+ +EI WG FVP+V+ ++G
Sbjct: 263 PLRDLTPQNL-KEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNG 321
Query: 325 RYSVDYSKFGNTVKVPTPLCTARQLDEDHSLLE 357
+Y D+S+F K +P CT D + LE
Sbjct: 322 KYVADFSQFEQIRK--SPDCTFYCADSEKQQLE 352
>gi|25777638 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 242 bits (618), Expect = 4e-64
Identities = 126/333 (37%), Positives = 201/333 (60%), Gaps = 7/333 (2%)
Query: 29 RQRRARFVSKKGNCNVAHKNIRE-QGRFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFA 87
+ R R +SK G+ NV + +LQD++TT++D+KW + L +F +F+ +W LF
Sbjct: 23 KANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFG 82
Query: 88 MAWWLIAFAHGDLAPSEGTAE--PCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLA 145
+ ++ IAF HGDL P E + PC+ + S + AFLFS+E Q TIG+G R +TEECP A
Sbjct: 83 VIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHA 142
Query: 146 ILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDL 205
I +L+ Q ++ +I + G K A+ +RAET+ FS AVI ++G+LC +++V ++
Sbjct: 143 IFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANM 202
Query: 206 RKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANS 265
RKS++I + ++++ + EGE + L+Q + S FL+ P+ YHV+D S
Sbjct: 203 RKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETS 262
Query: 266 PLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVA-EEDG 324
PL DL P +L ++ E++V+L VE+T Q+RTSY+ +EI WG FVP+V+ ++G
Sbjct: 263 PLRDLTPQNL-KEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNG 321
Query: 325 RYSVDYSKFGNTVKVPTPLCTARQLDEDHSLLE 357
+Y D+S+F K +P CT D + LE
Sbjct: 322 KYVADFSQFEQIRK--SPDCTFYCADSEKQQLE 352
>gi|156119627 potassium inwardly-rectifying channel J13 [Homo
sapiens]
Length = 360
Score = 161 bits (407), Expect = 1e-39
Identities = 107/323 (33%), Positives = 167/323 (51%), Gaps = 17/323 (5%)
Query: 30 QRRARFVSKKGNCNVAHKNIREQGRFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFAMA 89
QR R V+K G+ + + +L+D + L+D++W +L+F+ SF+ WL+FA+
Sbjct: 15 QRYRRMVTKDGHSTLQMDGAQRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAVL 74
Query: 90 WWLIAFAHGDL-----APSEGTAEPCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPL 144
W+++A +GDL AP E CV I SF++AF FS+E Q+TIG+G + +CP
Sbjct: 75 WYVLAEMNGDLELDHDAPPENHTI-CVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPS 133
Query: 145 AILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGD 204
AI +L +Q ++GLM+ A + G K A+ RA ++ F+ AV+A G+ + +V +
Sbjct: 134 AIALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQVAN 193
Query: 205 LRKSMIISATIHMQVVRKTTSPEGEVVPLHQ--VDIPMENGVGGNSIFLVAPLIIYHVID 262
R S + S + + + E E L+Q VD ++ F + PL YH I
Sbjct: 194 TRPSPLTSVRVSAVLYQ-----ERENGKLYQTSVDFHLDGISSDECPFFIFPLTYYHSIT 248
Query: 263 ANSPLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAE- 321
+SPL L + H E++V L + E TG Q RTSYL EI+ F ++
Sbjct: 249 PSSPLATLLQHENPSH--FELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLLTRG 306
Query: 322 EDGRYSVDYSKFGNTV-KVPTPL 343
G Y + F TV + PTPL
Sbjct: 307 SKGEYQIKMENFDKTVPEFPTPL 329
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.138 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,770,426
Number of Sequences: 37866
Number of extensions: 578711
Number of successful extensions: 1758
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 1637
Number of HSP's gapped (non-prelim): 31
length of query: 390
length of database: 18,247,518
effective HSP length: 104
effective length of query: 286
effective length of database: 14,309,454
effective search space: 4092503844
effective search space used: 4092503844
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.