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Search of human proteins with 13569938
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13569938 sialyltransferase 7E [Homo sapiens]
(336 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13569938 sialyltransferase 7E [Homo sapiens] 705 0.0
gi|21361444 sialytransferase 7F [Homo sapiens] 282 3e-76
gi|28373092 sialyltransferase 7D isoform a [Homo sapiens] 249 3e-66
gi|229892273 sialyltransferase 7C isoform 1 [Homo sapiens] 225 5e-59
gi|28373094 sialyltransferase 7D isoform b [Homo sapiens] 215 5e-56
gi|229892275 sialyltransferase 7C isoform 2 [Homo sapiens] 130 2e-30
gi|215272345 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2... 78 1e-14
gi|26190610 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 ... 78 1e-14
gi|110815855 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltran... 75 1e-13
gi|4506949 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 i... 73 4e-13
gi|27765091 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 ... 73 4e-13
gi|5174677 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransf... 72 7e-13
gi|215272347 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2... 68 1e-11
gi|5031999 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransf... 65 7e-11
gi|5454058 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [H... 62 7e-10
gi|5902082 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [H... 61 2e-09
gi|27765096 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [... 60 2e-09
gi|4506951 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [H... 60 2e-09
gi|28373086 sialyltransferase 6 isoform i [Homo sapiens] 60 4e-09
gi|28373082 sialyltransferase 6 isoform g [Homo sapiens] 60 4e-09
gi|28373078 sialyltransferase 6 isoform f [Homo sapiens] 60 4e-09
gi|28373070 sialyltransferase 6 isoform b [Homo sapiens] 60 4e-09
gi|28373068 sialyltransferase 6 isoform a [Homo sapiens] 60 4e-09
gi|5454060 sialyltransferase 6 isoform j [Homo sapiens] 60 4e-09
gi|109633046 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 ... 58 1e-08
gi|109633044 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 ... 58 1e-08
gi|4506953 alpha-2,8-sialyltransferase 1 [Homo sapiens] 56 5e-08
gi|28373074 sialyltransferase 6 isoform d [Homo sapiens] 56 5e-08
gi|54234057 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltrans... 55 9e-08
gi|192448440 sialyltransferase 7B [Homo sapiens] 52 7e-07
>gi|13569938 sialyltransferase 7E [Homo sapiens]
Length = 336
Score = 705 bits (1819), Expect = 0.0
Identities = 336/336 (100%), Positives = 336/336 (100%)
Query: 1 MKTLMRHGLAVCLALTTMCTSLLLVYSSLGGQKERPPQQQQQQQQQQQQASATGSSQPAA 60
MKTLMRHGLAVCLALTTMCTSLLLVYSSLGGQKERPPQQQQQQQQQQQQASATGSSQPAA
Sbjct: 1 MKTLMRHGLAVCLALTTMCTSLLLVYSSLGGQKERPPQQQQQQQQQQQQASATGSSQPAA 60
Query: 61 ESSTQQRPGVPAGPRPLDGYLGVADHKPLKMHCRDCALVTSSGHLLHSRQGSQIDQTECV 120
ESSTQQRPGVPAGPRPLDGYLGVADHKPLKMHCRDCALVTSSGHLLHSRQGSQIDQTECV
Sbjct: 61 ESSTQQRPGVPAGPRPLDGYLGVADHKPLKMHCRDCALVTSSGHLLHSRQGSQIDQTECV 120
Query: 121 IRMNDAPTRGYGRDVGNRTSLRVIAHSSIQRILRNRHDLLNVSQGTVFIFWGPSSYMRRD 180
IRMNDAPTRGYGRDVGNRTSLRVIAHSSIQRILRNRHDLLNVSQGTVFIFWGPSSYMRRD
Sbjct: 121 IRMNDAPTRGYGRDVGNRTSLRVIAHSSIQRILRNRHDLLNVSQGTVFIFWGPSSYMRRD 180
Query: 181 GKGQVYNNLHLLSQVLPRLKAFMITRHKMLQFDELFKQETGKDRKISNTWLSTGWFTMTI 240
GKGQVYNNLHLLSQVLPRLKAFMITRHKMLQFDELFKQETGKDRKISNTWLSTGWFTMTI
Sbjct: 181 GKGQVYNNLHLLSQVLPRLKAFMITRHKMLQFDELFKQETGKDRKISNTWLSTGWFTMTI 240
Query: 241 ALELCDRINVYGMVPPDFCRDPNHPSVPYHYYEPFGPDECTMYLSHERGRKGSHHRFITE 300
ALELCDRINVYGMVPPDFCRDPNHPSVPYHYYEPFGPDECTMYLSHERGRKGSHHRFITE
Sbjct: 241 ALELCDRINVYGMVPPDFCRDPNHPSVPYHYYEPFGPDECTMYLSHERGRKGSHHRFITE 300
Query: 301 KRVFKNWARTFNIHFFQPDWKPESLAINHPENKPVF 336
KRVFKNWARTFNIHFFQPDWKPESLAINHPENKPVF
Sbjct: 301 KRVFKNWARTFNIHFFQPDWKPESLAINHPENKPVF 336
>gi|21361444 sialytransferase 7F [Homo sapiens]
Length = 333
Score = 282 bits (721), Expect = 3e-76
Identities = 127/244 (52%), Positives = 174/244 (71%), Gaps = 2/244 (0%)
Query: 78 DGYLGVADHKPLKMHCRDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGN 137
DGY+ + +K L C C +V+SS HLL ++ G +I++ EC IRMNDAPT GY DVGN
Sbjct: 90 DGYVPILGNKTLPSRCHQCVIVSSSSHLLGTKLGPEIERAECTIRMNDAPTTGYSADVGN 149
Query: 138 RTSLRVIAHSSIQRILRNRHDLLNVSQGTVFIFWGPSSYMRRDGKGQVYNNLHLLSQVLP 197
+T+ RV+AHSS+ R+LR + +N + TVFIFWGP S M++ +G + + V P
Sbjct: 150 KTTYRVVAHSSVFRVLRRPQEFVNRTPETVFIFWGPPSKMQKP-QGSLVRVIQRAGLVFP 208
Query: 198 RLKAFMITRHKMLQFDELFKQETGKDRKISNTWLSTGWFTMTIALELCDRINVYGMVPPD 257
++A+ ++ +M QFD+LF+ ETGKDR+ S++WLSTGWFTM IA+ELCD ++VYGMVPP+
Sbjct: 209 NMEAYAVSPGRMRQFDDLFRGETGKDREKSHSWLSTGWFTMVIAVELCDHVHVYGMVPPN 268
Query: 258 FC-RDPNHPSVPYHYYEPFGPDECTMYLSHERGRKGSHHRFITEKRVFKNWARTFNIHFF 316
+C + P +PYHYYEP GPDEC Y+ +E RKG+HHRFITEKRVF +WA+ + I F
Sbjct: 269 YCSQRPRLQRMPYHYYEPKGPDECVTYIQNEHSRKGNHHRFITEKRVFSSWAQLYGITFS 328
Query: 317 QPDW 320
P W
Sbjct: 329 HPSW 332
>gi|28373092 sialyltransferase 7D isoform a [Homo sapiens]
Length = 302
Score = 249 bits (635), Expect = 3e-66
Identities = 125/261 (47%), Positives = 169/261 (64%), Gaps = 3/261 (1%)
Query: 64 TQQRPGVPAGPRPLDGYLGVADHKPL-KMHCRDCALVTSSGHLLHSRQGSQIDQTECVIR 122
T RP VP GP GY V D KPL + CR CA+V+SSG +L S G++ID ECV R
Sbjct: 44 TGSRPTVP-GPLHFSGYSSVPDGKPLVREPCRSCAVVSSSGQMLGSGLGAEIDSAECVFR 102
Query: 123 MNDAPTRGYGRDVGNRTSLRVIAHSSIQRILRNRHDLLNVSQGTVFIFWGPSSYMRRDGK 182
MN APT G+ DVG R++LRV++H+S+ +LRN ++ T+++ WG +M R
Sbjct: 103 MNQAPTVGFEADVGQRSTLRVVSHTSVPLLLRNYSHYFQKARDTLYMVWGQGRHMDRVLG 162
Query: 183 GQVYNNLHLLSQVLPRLKAFMITRHKMLQFDELFKQETGKDRKISNTWLSTGWFTMTIAL 242
G+ Y L L+++ P L+ + T M D++F+ ETGK+R+ S ++LSTGWFTM +AL
Sbjct: 163 GRTYRTLLQLTRMYPGLQVYTFTERMMAYCDQIFQDETGKNRRQSGSFLSTGWFTMILAL 222
Query: 243 ELCDRINVYGMVPPDFCRDPNHPSVPYHYYEPFGPDECTMYLSHERGRKGSHHRFITEKR 302
ELC+ I VYGMV +CR+ +HPSVPYHY+E DEC MYL+HE+ + S HRFITEK
Sbjct: 223 ELCEEIVVYGMVSDSYCREKSHPSVPYHYFEKGRLDECQMYLAHEQAPR-SAHRFITEKA 281
Query: 303 VFKNWARTFNIHFFQPDWKPE 323
VF WA+ I F P W+ E
Sbjct: 282 VFSRWAKKRPIVFAHPSWRTE 302
>gi|229892273 sialyltransferase 7C isoform 1 [Homo sapiens]
Length = 305
Score = 225 bits (573), Expect = 5e-59
Identities = 104/242 (42%), Positives = 153/242 (63%), Gaps = 2/242 (0%)
Query: 79 GYLGVADHKPLKMHCRDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNR 138
GY+ V +PL++ C CA+V++SG ++ + G++ID++ C+ RMN+APT+GY DVG
Sbjct: 63 GYINVKTQEPLQLDCDLCAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRM 122
Query: 139 TSLRVIAHSSIQRILRNRHDLLNVSQGTVFIFWGPSSYMRRDGKGQVYNNLHLLSQVLPR 198
T +RV++H+S+ +L+N + T+++ WGP MR+DG G VYN L + P
Sbjct: 123 TMIRVVSHTSVPLLLKNPDYFFKEANTTIYVIWGPFRNMRKDGNGIVYNMLKKTVGIYPN 182
Query: 199 LKAFMITRHKMLQFDELFKQETGKDRKISNTWLSTGWFTMTIALELCDRINVYGMVPPDF 258
+ ++ T +M D +FK+ETGKDR S ++LSTGWFT +A++ C I+VYGM+ +
Sbjct: 183 AQIYVTTEKRMSYCDGVFKKETGKDRVQSGSYLSTGWFTFLLAMDACYGIHVYGMINDTY 242
Query: 259 CRDPNHPSVPYHYYEPFGPDECTMYLSHERGRKGSHHRFITEKRVFKNWARTFNIHFFQP 318
C+ + VPYHYYE G DEC Y HE G HRFITEK+VF WA+ I F P
Sbjct: 243 CKTEGYRKVPYHYYEQ-GRDECDEYFLHEHAPYGG-HRFITEKKVFAKWAKKHRIIFTHP 300
Query: 319 DW 320
+W
Sbjct: 301 NW 302
>gi|28373094 sialyltransferase 7D isoform b [Homo sapiens]
Length = 218
Score = 215 bits (547), Expect = 5e-56
Identities = 103/219 (47%), Positives = 144/219 (65%), Gaps = 1/219 (0%)
Query: 105 LLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRVIAHSSIQRILRNRHDLLNVSQ 164
+L S G++ID ECV RMN APT G+ DVG R++LRV++H+S+ +LRN ++
Sbjct: 1 MLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLLLRNYSHYFQKAR 60
Query: 165 GTVFIFWGPSSYMRRDGKGQVYNNLHLLSQVLPRLKAFMITRHKMLQFDELFKQETGKDR 224
T+++ WG +M R G+ Y L L+++ P L+ + T M D++F+ ETGK+R
Sbjct: 61 DTLYMVWGQGRHMDRVLGGRTYRTLLQLTRMYPGLQVYTFTERMMAYCDQIFQDETGKNR 120
Query: 225 KISNTWLSTGWFTMTIALELCDRINVYGMVPPDFCRDPNHPSVPYHYYEPFGPDECTMYL 284
+ S ++LSTGWFTM +ALELC+ I VYGMV +CR+ +HPSVPYHY+E DEC MYL
Sbjct: 121 RQSGSFLSTGWFTMILALELCEEIVVYGMVSDSYCREKSHPSVPYHYFEKGRLDECQMYL 180
Query: 285 SHERGRKGSHHRFITEKRVFKNWARTFNIHFFQPDWKPE 323
+HE+ + S HRFITEK VF WA+ I F P W+ E
Sbjct: 181 AHEQAPR-SAHRFITEKAVFSRWAKKRPIVFAHPSWRTE 218
>gi|229892275 sialyltransferase 7C isoform 2 [Homo sapiens]
Length = 210
Score = 130 bits (326), Expect = 2e-30
Identities = 57/145 (39%), Positives = 93/145 (64%)
Query: 79 GYLGVADHKPLKMHCRDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNR 138
GY+ V +PL++ C CA+V++SG ++ + G++ID++ C+ RMN+APT+GY DVG
Sbjct: 63 GYINVKTQEPLQLDCDLCAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRM 122
Query: 139 TSLRVIAHSSIQRILRNRHDLLNVSQGTVFIFWGPSSYMRRDGKGQVYNNLHLLSQVLPR 198
T +RV++H+S+ +L+N + T+++ WGP MR+DG G VYN L + P
Sbjct: 123 TMIRVVSHTSVPLLLKNPDYFFKEANTTIYVIWGPFRNMRKDGNGIVYNMLKKTVGIYPN 182
Query: 199 LKAFMITRHKMLQFDELFKQETGKD 223
+ ++ T +M D +FK+ETGKD
Sbjct: 183 AQIYVTTEKRMSYCDGVFKKETGKD 207
>gi|215272345 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
isoform a [Homo sapiens]
Length = 529
Score = 78.2 bits (191), Expect = 1e-14
Identities = 63/256 (24%), Positives = 116/256 (45%), Gaps = 38/256 (14%)
Query: 94 RDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRVIAHSSIQRIL 153
R CA+V S+G +L+S G +ID + V+R N APTRGY +DVGN+T++R+I + Q +
Sbjct: 294 RSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRII---NSQILT 350
Query: 154 RNRHDLLNVS--QGTVFIFWGPSSYMRRDGKGQVYNNLHLLSQVL------PRLKAFMIT 205
H ++ S + + + W P+ Y + +L + + P +++
Sbjct: 351 NPSHHFIDSSLYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILH 410
Query: 206 RHKMLQFDELFKQETGKDRKISNTWLSTGWFTMTIALELCDRINVYGMVP----PDFCRD 261
+ Q ++ ++ T KI S+G+ + I + +C ++VY +P + C
Sbjct: 411 PKFIWQLWDIIQENT--KEKIQPNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTELC-- 466
Query: 262 PNHPSVPYHYYEPFGPDECTMYLSHERGRKGSHHRFITEKRVFK--NWARTFNIHFFQPD 319
HY+E + CT+ G++H + EK + + N ++H
Sbjct: 467 --------HYHELYYDAACTL---------GAYHPLLYEKLLVQRLNMGTQGDLHRKGKV 509
Query: 320 WKPESLAINHPENKPV 335
P A++ P PV
Sbjct: 510 VLPGFQAVHCPAPSPV 525
>gi|26190610 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
isoform a [Homo sapiens]
Length = 529
Score = 78.2 bits (191), Expect = 1e-14
Identities = 63/256 (24%), Positives = 116/256 (45%), Gaps = 38/256 (14%)
Query: 94 RDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRVIAHSSIQRIL 153
R CA+V S+G +L+S G +ID + V+R N APTRGY +DVGN+T++R+I + Q +
Sbjct: 294 RSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRII---NSQILT 350
Query: 154 RNRHDLLNVS--QGTVFIFWGPSSYMRRDGKGQVYNNLHLLSQVL------PRLKAFMIT 205
H ++ S + + + W P+ Y + +L + + P +++
Sbjct: 351 NPSHHFIDSSLYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILH 410
Query: 206 RHKMLQFDELFKQETGKDRKISNTWLSTGWFTMTIALELCDRINVYGMVP----PDFCRD 261
+ Q ++ ++ T KI S+G+ + I + +C ++VY +P + C
Sbjct: 411 PKFIWQLWDIIQENT--KEKIQPNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTELC-- 466
Query: 262 PNHPSVPYHYYEPFGPDECTMYLSHERGRKGSHHRFITEKRVFK--NWARTFNIHFFQPD 319
HY+E + CT+ G++H + EK + + N ++H
Sbjct: 467 --------HYHELYYDAACTL---------GAYHPLLYEKLLVQRLNMGTQGDLHRKGKV 509
Query: 320 WKPESLAINHPENKPV 335
P A++ P PV
Sbjct: 510 VLPGFQAVHCPAPSPV 525
>gi|110815855 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 3 [Homo sapiens]
Length = 380
Score = 74.7 bits (182), Expect = 1e-13
Identities = 57/203 (28%), Positives = 91/203 (44%), Gaps = 29/203 (14%)
Query: 89 LKMHCRDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRVIAHSS 148
+ H CA+V +SG L S+ G +ID+++ V R N APT + RDVG +T+L S
Sbjct: 155 MNKHYNICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNPSI 214
Query: 149 IQRILRN-------RHDLLNVSQGTVFIFWGPSSYMRRDGKGQVYNNLHLLSQVLPRLKA 201
+++ N + L++ + I W P+ + H + V L
Sbjct: 215 LEKYYNNLLTIQDRNNFFLSLKKLDGAILWIPAFF------------FHTSATVTRTLVD 262
Query: 202 FMITRHKMLQFDELFK-------QETGKDRKISNTWLSTGWFTMTIALELCDRINVYGMV 254
F + L+ + K++ +S LSTG T+A +C+ I++YG
Sbjct: 263 FFVEHRGQLKVQLAWPGNIMQHVNRYWKNKHLSPKRLSTGILMYTLASAICEEIHLYGFW 322
Query: 255 PPDFCRDPN-HPSVPYHYYEPFG 276
P F DPN +PYHYY+ G
Sbjct: 323 PFGF--DPNTREDLPYHYYDKKG 343
>gi|4506949 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
isoform a [Homo sapiens]
Length = 406
Score = 72.8 bits (177), Expect = 4e-13
Identities = 55/221 (24%), Positives = 104/221 (47%), Gaps = 33/221 (14%)
Query: 96 CALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRVIAHSSIQRILRN 155
CA+V+S+G L S+ G +ID + V+R N APT + +DVG +T++R++ + R
Sbjct: 184 CAVVSSAGSLKSSQLGREIDDHDAVLRFNGAPTANFQQDVGTKTTIRLMNSQLVTTEKRF 243
Query: 156 RHDLLNVSQGTVFIFWGPSSY------MRRDGKGQVYNNLHLLSQVLPRLKAFMITRHKM 209
D L ++G + I W PS Y ++ +NN ++ P +++
Sbjct: 244 LKDSL-YNEG-ILIVWDPSVYHSDIPKWYQNPDYNFFNNYKTYRKLHPNQPFYILKPQMP 301
Query: 210 LQFDELFKQETGKDRKISNTWLSTGWFTMTIALELCDRINVYGMVP----PDFCRDPNHP 265
+ ++ ++ + ++ I S+G + I + LCD++++Y +P D C
Sbjct: 302 WELWDILQEISPEE--IQPNPPSSGMLGIIIMMTLCDQVDIYEFLPSKRKTDVC------ 353
Query: 266 SVPYHYYEPFGPDECTMYLSHERGRKGSHHRFITEKRVFKN 306
+YY+ F CTM G++H + EK + K+
Sbjct: 354 ----YYYQKFFDSACTM---------GAYHPLLYEKNLVKH 381
>gi|27765091 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
isoform a [Homo sapiens]
Length = 406
Score = 72.8 bits (177), Expect = 4e-13
Identities = 55/221 (24%), Positives = 104/221 (47%), Gaps = 33/221 (14%)
Query: 96 CALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRVIAHSSIQRILRN 155
CA+V+S+G L S+ G +ID + V+R N APT + +DVG +T++R++ + R
Sbjct: 184 CAVVSSAGSLKSSQLGREIDDHDAVLRFNGAPTANFQQDVGTKTTIRLMNSQLVTTEKRF 243
Query: 156 RHDLLNVSQGTVFIFWGPSSY------MRRDGKGQVYNNLHLLSQVLPRLKAFMITRHKM 209
D L ++G + I W PS Y ++ +NN ++ P +++
Sbjct: 244 LKDSL-YNEG-ILIVWDPSVYHSDIPKWYQNPDYNFFNNYKTYRKLHPNQPFYILKPQMP 301
Query: 210 LQFDELFKQETGKDRKISNTWLSTGWFTMTIALELCDRINVYGMVP----PDFCRDPNHP 265
+ ++ ++ + ++ I S+G + I + LCD++++Y +P D C
Sbjct: 302 WELWDILQEISPEE--IQPNPPSSGMLGIIIMMTLCDQVDIYEFLPSKRKTDVC------ 353
Query: 266 SVPYHYYEPFGPDECTMYLSHERGRKGSHHRFITEKRVFKN 306
+YY+ F CTM G++H + EK + K+
Sbjct: 354 ----YYYQKFFDSACTM---------GAYHPLLYEKNLVKH 381
>gi|5174677 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 2 [Homo sapiens]
Length = 375
Score = 72.0 bits (175), Expect = 7e-13
Identities = 70/204 (34%), Positives = 88/204 (43%), Gaps = 36/204 (17%)
Query: 88 PLK-MHCRDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRVIAH 146
PLK H CA+V +SG LL+S G +ID VIR N AP + Y RDVG +T L +
Sbjct: 148 PLKNKHFGTCAIVGNSGVLLNSGCGQEIDAHSFVIRCNLAPVQEYARDVGLKTDLVTMNP 207
Query: 147 SSIQRILRNRHDLLNVSQGTVF----------IFWGPSSYMRRDGKGQV--YNNLHLLSQ 194
S IQR DL+N + I W P ++M R GK +V N L L
Sbjct: 208 SVIQRAF---EDLVNATWREKLLQRLHSLNGSILWIP-AFMARGGKERVEWVNELILKHH 263
Query: 195 V-----LPRLKAFMITRHKMLQFDELFKQETGKDRKISNTWLSTGWFTMTIALELCDRIN 249
V P L+ R L K+ T TG T+A C +I
Sbjct: 264 VNVRTAYPSLRLLHAVRGYWLTNKVHIKRPT------------TGLLMYTLATRFCKQIY 311
Query: 250 VYGMVPPDFCRDPNHPSVPYHYYE 273
+YG P F D N V YHYY+
Sbjct: 312 LYGFWP--FPLDQNQNPVKYHYYD 333
>gi|215272347 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
isoform b [Homo sapiens]
Length = 466
Score = 67.8 bits (164), Expect = 1e-11
Identities = 33/85 (38%), Positives = 53/85 (62%), Gaps = 5/85 (5%)
Query: 94 RDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRVIAHSSIQRIL 153
R CA+V S+G +L+S G +ID + V+R N APTRGY +DVGN+T++R+I + Q +
Sbjct: 294 RSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRII---NSQILT 350
Query: 154 RNRHDLLNVS--QGTVFIFWGPSSY 176
H ++ S + + + W P+ Y
Sbjct: 351 NPSHHFIDSSLYKDVILVAWDPAPY 375
>gi|5031999 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 4 isoform a [Homo sapiens]
Length = 359
Score = 65.5 bits (158), Expect = 7e-11
Identities = 57/193 (29%), Positives = 82/193 (42%), Gaps = 27/193 (13%)
Query: 94 RDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRVIAHSSIQRI- 152
+ CA+V +SG LL S G +ID VIR N AP + DVG ++ + S +QR
Sbjct: 140 KTCAVVGNSGILLDSECGKEIDSHNFVIRCNLAPVVEFAADVGTKSDFITMNPSVVQRAF 199
Query: 153 --LRNRHD----LLNVSQGTVFIFWGPSSYMRRDGKGQVYNNLHLLSQVL------PRLK 200
RN D + +S + W P+ ++ K + N +L L P L+
Sbjct: 200 GGFRNESDREKFVHRLSMLNDSVLWIPAFMVKGGEKHVEWVNALILKNKLKVRTAYPSLR 259
Query: 201 AFMITRHKMLQFDELFKQETGKDRKISNTWLSTGWFTMTIALELCDRINVYGMVPPDFCR 260
R L K+ STG T+A CD I++YG P F +
Sbjct: 260 LIHAVRGYWL------------TNKVPIKRPSTGLLMYTLATRFCDEIHLYGFWP--FPK 305
Query: 261 DPNHPSVPYHYYE 273
D N +V YHYY+
Sbjct: 306 DLNGKAVKYHYYD 318
>gi|5454058 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [Homo
sapiens]
Length = 329
Score = 62.0 bits (149), Expect = 7e-10
Identities = 54/189 (28%), Positives = 88/189 (46%), Gaps = 12/189 (6%)
Query: 91 MHCRDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRVIAHSS-- 148
+ CR C +V + L +S G I++ + VIR+N+AP GY DVG++T++R+ S
Sbjct: 111 LRCRRCVVVGNGHRLRNSSLGDAINKYDVVIRLNNAPVAGYEGDVGSKTTMRLFYPESAH 170
Query: 149 IQRILRNRHD--LLNVSQGTVFIFWGPS--SYMRRDGKGQVYNNLHLLSQVLPRLKAFMI 204
+ N D L+ V+ + W + S +R KG + L+ V P+ +
Sbjct: 171 FDPKVENNPDTLLVLVAFKAMDFHWIETILSDKKRVRKG-FWKQPPLIWDVNPKQIRILN 229
Query: 205 TRHKMLQFDELFKQETGKDRKISNTWLSTGWFTMTIALELCDRINVYGMVPPDFCRDPNH 264
+ D+L + RKI +TG +T+AL LCD +++ G P D +
Sbjct: 230 PFFMEIAADKLLSLPMQQPRKIKQK-PTTGLLAITLALHLCDLVHIAGFGYP----DAYN 284
Query: 265 PSVPYHYYE 273
HYYE
Sbjct: 285 KKQTIHYYE 293
>gi|5902082 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [Homo
sapiens]
Length = 350
Score = 60.8 bits (146), Expect = 2e-09
Identities = 47/162 (29%), Positives = 76/162 (46%), Gaps = 14/162 (8%)
Query: 93 CRDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRVIAHSSIQRI 152
CR CA+V +SG+L S G +D ++RMN APT G+ +DVG+RT+ + S + +
Sbjct: 149 CRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAPTVGFEQDVGSRTTHHFMYPESAKNL 208
Query: 153 LRNRHDLLNVSQGTVFIFWGPSSYMRRDGKGQVYNNLHLLSQVLPRLKAFMITRHKMLQF 212
N +L V + + W S+ GQ+ +K+F+ + +Q
Sbjct: 209 PANVSFVL-VPFKVLDLLWIASAL----STGQI-------RFTYAPVKSFLRVDKEKVQI 256
Query: 213 --DELFKQETGKDRKISNTWLSTGWFTMTIALELCDRINVYG 252
FK + + + STG + AL +CD +NVYG
Sbjct: 257 YNPAFFKYIHDRWTEHHGRYPSTGMLVLFFALHVCDEVNVYG 298
>gi|27765096 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
[Homo sapiens]
Length = 340
Score = 60.5 bits (145), Expect = 2e-09
Identities = 45/167 (26%), Positives = 80/167 (47%), Gaps = 24/167 (14%)
Query: 93 CRDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRVIAHSSIQRI 152
CR CA+V +SG+L S G +ID + V+RMN APT G+ DVG +T+ ++ S R
Sbjct: 139 CRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGFEADVGTKTTHHLVYPESF-RE 197
Query: 153 LRNRHDLLNVSQGTVFIFWGPSSYMRRDGKGQVYNNLHLLSQVLPRLKAFMITRHKMLQF 212
L + ++ V T+ + W S+ G + + +P + + K+L +
Sbjct: 198 LGDNVSMILVPFKTIDLEWVVSAIT----TGTISHT------YIPVPAKIRVKQDKILIY 247
Query: 213 DELFKQETGKDRKISNTWL-------STGWFTMTIALELCDRINVYG 252
F + + + WL STG ++ ++ +CD +++YG
Sbjct: 248 HPAF------IKYVFDNWLQGHGRYPSTGILSVIFSMHVCDEVDLYG 288
>gi|4506951 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [Homo
sapiens]
Length = 340
Score = 60.5 bits (145), Expect = 2e-09
Identities = 45/167 (26%), Positives = 80/167 (47%), Gaps = 24/167 (14%)
Query: 93 CRDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRVIAHSSIQRI 152
CR CA+V +SG+L S G +ID + V+RMN APT G+ DVG +T+ ++ S R
Sbjct: 139 CRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGFEADVGTKTTHHLVYPESF-RE 197
Query: 153 LRNRHDLLNVSQGTVFIFWGPSSYMRRDGKGQVYNNLHLLSQVLPRLKAFMITRHKMLQF 212
L + ++ V T+ + W S+ G + + +P + + K+L +
Sbjct: 198 LGDNVSMILVPFKTIDLEWVVSAIT----TGTISHT------YIPVPAKIRVKQDKILIY 247
Query: 213 DELFKQETGKDRKISNTWL-------STGWFTMTIALELCDRINVYG 252
F + + + WL STG ++ ++ +CD +++YG
Sbjct: 248 HPAF------IKYVFDNWLQGHGRYPSTGILSVIFSMHVCDEVDLYG 288
>gi|28373086 sialyltransferase 6 isoform i [Homo sapiens]
Length = 413
Score = 59.7 bits (143), Expect = 4e-09
Identities = 55/195 (28%), Positives = 89/195 (45%), Gaps = 24/195 (12%)
Query: 91 MHCRDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRV-IAHSSI 149
+ CR C +V + G L + GS+ID + V+R+N AP +G+ +DVG++T+LR+ ++
Sbjct: 193 LRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAM 252
Query: 150 QRILRNRHDLLNVSQGTVFIFWGPSSYMRRDGKGQVYNNLHLLSQVLPRLKAFMITRH-- 207
QR + D L V G W ++ K VY S + A + +
Sbjct: 253 QRPEQYERDSLFVLAG---FKWQDFKWL----KYIVYKERVSASDGFWKSVATRVPKEPP 305
Query: 208 KMLQFDELFKQE---TGKDRKISNTWL------STGWFTMTIALELCDRINVYGMVPPDF 258
++ + F QE T +N + + G +T+AL CD + V G F
Sbjct: 306 EIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAG-----F 360
Query: 259 CRDPNHPSVPYHYYE 273
D + P+ P HYYE
Sbjct: 361 GYDMSTPNAPLHYYE 375
>gi|28373082 sialyltransferase 6 isoform g [Homo sapiens]
Length = 359
Score = 59.7 bits (143), Expect = 4e-09
Identities = 55/195 (28%), Positives = 89/195 (45%), Gaps = 24/195 (12%)
Query: 91 MHCRDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRV-IAHSSI 149
+ CR C +V + G L + GS+ID + V+R+N AP +G+ +DVG++T+LR+ ++
Sbjct: 139 LRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAM 198
Query: 150 QRILRNRHDLLNVSQGTVFIFWGPSSYMRRDGKGQVYNNLHLLSQVLPRLKAFMITRH-- 207
QR + D L V G W ++ K VY S + A + +
Sbjct: 199 QRPEQYERDSLFVLAG---FKWQDFKWL----KYIVYKERVSASDGFWKSVATRVPKEPP 251
Query: 208 KMLQFDELFKQE---TGKDRKISNTWL------STGWFTMTIALELCDRINVYGMVPPDF 258
++ + F QE T +N + + G +T+AL CD + V G F
Sbjct: 252 EIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAG-----F 306
Query: 259 CRDPNHPSVPYHYYE 273
D + P+ P HYYE
Sbjct: 307 GYDMSTPNAPLHYYE 321
>gi|28373078 sialyltransferase 6 isoform f [Homo sapiens]
Length = 429
Score = 59.7 bits (143), Expect = 4e-09
Identities = 55/195 (28%), Positives = 89/195 (45%), Gaps = 24/195 (12%)
Query: 91 MHCRDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRV-IAHSSI 149
+ CR C +V + G L + GS+ID + V+R+N AP +G+ +DVG++T+LR+ ++
Sbjct: 209 LRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAM 268
Query: 150 QRILRNRHDLLNVSQGTVFIFWGPSSYMRRDGKGQVYNNLHLLSQVLPRLKAFMITRH-- 207
QR + D L V G W ++ K VY S + A + +
Sbjct: 269 QRPEQYERDSLFVLAG---FKWQDFKWL----KYIVYKERVSASDGFWKSVATRVPKEPP 321
Query: 208 KMLQFDELFKQE---TGKDRKISNTWL------STGWFTMTIALELCDRINVYGMVPPDF 258
++ + F QE T +N + + G +T+AL CD + V G F
Sbjct: 322 EIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAG-----F 376
Query: 259 CRDPNHPSVPYHYYE 273
D + P+ P HYYE
Sbjct: 377 GYDMSTPNAPLHYYE 391
>gi|28373070 sialyltransferase 6 isoform b [Homo sapiens]
Length = 390
Score = 59.7 bits (143), Expect = 4e-09
Identities = 55/195 (28%), Positives = 89/195 (45%), Gaps = 24/195 (12%)
Query: 91 MHCRDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRV-IAHSSI 149
+ CR C +V + G L + GS+ID + V+R+N AP +G+ +DVG++T+LR+ ++
Sbjct: 170 LRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAM 229
Query: 150 QRILRNRHDLLNVSQGTVFIFWGPSSYMRRDGKGQVYNNLHLLSQVLPRLKAFMITRH-- 207
QR + D L V G W ++ K VY S + A + +
Sbjct: 230 QRPEQYERDSLFVLAG---FKWQDFKWL----KYIVYKERVSASDGFWKSVATRVPKEPP 282
Query: 208 KMLQFDELFKQE---TGKDRKISNTWL------STGWFTMTIALELCDRINVYGMVPPDF 258
++ + F QE T +N + + G +T+AL CD + V G F
Sbjct: 283 EIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAG-----F 337
Query: 259 CRDPNHPSVPYHYYE 273
D + P+ P HYYE
Sbjct: 338 GYDMSTPNAPLHYYE 352
>gi|28373068 sialyltransferase 6 isoform a [Homo sapiens]
Length = 444
Score = 59.7 bits (143), Expect = 4e-09
Identities = 55/195 (28%), Positives = 89/195 (45%), Gaps = 24/195 (12%)
Query: 91 MHCRDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRV-IAHSSI 149
+ CR C +V + G L + GS+ID + V+R+N AP +G+ +DVG++T+LR+ ++
Sbjct: 224 LRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAM 283
Query: 150 QRILRNRHDLLNVSQGTVFIFWGPSSYMRRDGKGQVYNNLHLLSQVLPRLKAFMITRH-- 207
QR + D L V G W ++ K VY S + A + +
Sbjct: 284 QRPEQYERDSLFVLAG---FKWQDFKWL----KYIVYKERVSASDGFWKSVATRVPKEPP 336
Query: 208 KMLQFDELFKQE---TGKDRKISNTWL------STGWFTMTIALELCDRINVYGMVPPDF 258
++ + F QE T +N + + G +T+AL CD + V G F
Sbjct: 337 EIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAG-----F 391
Query: 259 CRDPNHPSVPYHYYE 273
D + P+ P HYYE
Sbjct: 392 GYDMSTPNAPLHYYE 406
>gi|5454060 sialyltransferase 6 isoform j [Homo sapiens]
Length = 375
Score = 59.7 bits (143), Expect = 4e-09
Identities = 55/195 (28%), Positives = 89/195 (45%), Gaps = 24/195 (12%)
Query: 91 MHCRDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRV-IAHSSI 149
+ CR C +V + G L + GS+ID + V+R+N AP +G+ +DVG++T+LR+ ++
Sbjct: 155 LRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAM 214
Query: 150 QRILRNRHDLLNVSQGTVFIFWGPSSYMRRDGKGQVYNNLHLLSQVLPRLKAFMITRH-- 207
QR + D L V G W ++ K VY S + A + +
Sbjct: 215 QRPEQYERDSLFVLAG---FKWQDFKWL----KYIVYKERVSASDGFWKSVATRVPKEPP 267
Query: 208 KMLQFDELFKQE---TGKDRKISNTWL------STGWFTMTIALELCDRINVYGMVPPDF 258
++ + F QE T +N + + G +T+AL CD + V G F
Sbjct: 268 EIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAG-----F 322
Query: 259 CRDPNHPSVPYHYYE 273
D + P+ P HYYE
Sbjct: 323 GYDMSTPNAPLHYYE 337
>gi|109633046 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
isoform 2 [Homo sapiens]
Length = 395
Score = 58.2 bits (139), Expect = 1e-08
Identities = 50/199 (25%), Positives = 86/199 (43%), Gaps = 32/199 (16%)
Query: 93 CRDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRV--------- 143
CR C ++ S G L G ++Q + VIR+N AP GY VGN+T++R+
Sbjct: 169 CRRCVVIGSGGILHGLELGHTLNQFDVVIRLNSAPVEGYSEHVGNKTTIRMTYPEGAPLS 228
Query: 144 ----IAHSSIQRILRNRHD---LLNVSQGTVFIFWGPSSYMRRDGKGQVYNNLH--LLSQ 194
++ +L D L + + FW + ++ + H +L+
Sbjct: 229 DLEYYSNDLFVAVLFKSVDFNWLQAMVKKETLPFWVRLFFWKQVAEKIPLQPKHFRILNP 288
Query: 195 VLPRLKAFMITRHKMLQFDELFKQETGKDRKISNTWLSTGWFTMTIALELCDRINVYGMV 254
V+ + AF I LQ+ E + G+D+ + + G + +A LCD +++ G
Sbjct: 289 VIIKETAFDI-----LQYSEPQSRFWGRDKNVP----TIGVIAVVLATHLCDEVSLAG-- 337
Query: 255 PPDFCRDPNHPSVPYHYYE 273
F D N P P HY++
Sbjct: 338 ---FGYDLNQPRTPLHYFD 353
>gi|109633044 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
isoform 1 [Homo sapiens]
Length = 418
Score = 58.2 bits (139), Expect = 1e-08
Identities = 50/199 (25%), Positives = 86/199 (43%), Gaps = 32/199 (16%)
Query: 93 CRDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRV--------- 143
CR C ++ S G L G ++Q + VIR+N AP GY VGN+T++R+
Sbjct: 192 CRRCVVIGSGGILHGLELGHTLNQFDVVIRLNSAPVEGYSEHVGNKTTIRMTYPEGAPLS 251
Query: 144 ----IAHSSIQRILRNRHD---LLNVSQGTVFIFWGPSSYMRRDGKGQVYNNLH--LLSQ 194
++ +L D L + + FW + ++ + H +L+
Sbjct: 252 DLEYYSNDLFVAVLFKSVDFNWLQAMVKKETLPFWVRLFFWKQVAEKIPLQPKHFRILNP 311
Query: 195 VLPRLKAFMITRHKMLQFDELFKQETGKDRKISNTWLSTGWFTMTIALELCDRINVYGMV 254
V+ + AF I LQ+ E + G+D+ + + G + +A LCD +++ G
Sbjct: 312 VIIKETAFDI-----LQYSEPQSRFWGRDKNVP----TIGVIAVVLATHLCDEVSLAG-- 360
Query: 255 PPDFCRDPNHPSVPYHYYE 273
F D N P P HY++
Sbjct: 361 ---FGYDLNQPRTPLHYFD 376
>gi|4506953 alpha-2,8-sialyltransferase 1 [Homo sapiens]
Length = 356
Score = 55.8 bits (133), Expect = 5e-08
Identities = 50/202 (24%), Positives = 88/202 (43%), Gaps = 34/202 (16%)
Query: 88 PLKMHCRDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRG-YGRDVGNRTSLRVIAH 146
P ++ + CA+V + G L S G QID+ V+R N P Y +DVG+++ L
Sbjct: 130 PFQLPLKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKSQLVTANP 189
Query: 147 SSIQRILRNRHDLLNVSQGTVFIFWGPSSYMRRDGKGQVYNNLHLLSQVL-------PRL 199
S I++ +N + W +++ ++YN+ ++ P L
Sbjct: 190 SIIRQRFQN-------------LLWSRKTFV---DNMKIYNHSYIYMPAFSMKTGTEPSL 233
Query: 200 KAFMI-----TRHKMLQFDELFKQETGK---DRKISNTWLSTGWFTMTIALELCDRINVY 251
+ + +L + F + GK R I LSTG F ++ AL LC+ + +Y
Sbjct: 234 RVYYTLSDVGANQTVLFANPNFLRSIGKFWKSRGIHAKRLSTGLFLVSAALGLCEEVAIY 293
Query: 252 GMVPPDFCRDPNHPSVPYHYYE 273
G P F + + + +HYY+
Sbjct: 294 GFWP--FSVNMHEQPISHHYYD 313
>gi|28373074 sialyltransferase 6 isoform d [Homo sapiens]
Length = 277
Score = 55.8 bits (133), Expect = 5e-08
Identities = 28/76 (36%), Positives = 46/76 (60%), Gaps = 1/76 (1%)
Query: 91 MHCRDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRV-IAHSSI 149
+ CR C +V + G L + GS+ID + V+R+N AP +G+ +DVG++T+LR+ ++
Sbjct: 155 LRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAM 214
Query: 150 QRILRNRHDLLNVSQG 165
QR + D L V G
Sbjct: 215 QRPEQYERDSLFVLAG 230
>gi|54234057 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 6 [Homo sapiens]
Length = 398
Score = 55.1 bits (131), Expect = 9e-08
Identities = 53/185 (28%), Positives = 84/185 (45%), Gaps = 16/185 (8%)
Query: 96 CALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRG-YGRDVGNRTSLRVIAHSSIQRILR 154
CA+V + G L S G++ID+++ V R N PT G +DVG++T+L I S I
Sbjct: 186 CAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNLVTINPSIITLKYG 245
Query: 155 NRHDLLNV------SQGTVFIFWGPSSYMRRDGKGQVYNNLHLLSQVLPRLKAFMITRHK 208
N + + + G F S+ R G + + L + R K + K
Sbjct: 246 NLKEKKALFLEDIATYGDAFFLLPAFSF--RANTGTSFKVYYTLEESKARQKV-LFFHPK 302
Query: 209 MLQFDELFKQETGKDRKISNTWLSTGWFTMTIALELCDRINVYGMVPPDFCRDPNHPSVP 268
L+ LF + G ++ LSTG ++A+ELC + +YG P F + V
Sbjct: 303 YLKDLALFWRTKG----VTAYRLSTGLMITSVAVELCKNVKLYGFWP--FSKTVEDIPVS 356
Query: 269 YHYYE 273
+HYY+
Sbjct: 357 HHYYD 361
>gi|192448440 sialyltransferase 7B [Homo sapiens]
Length = 374
Score = 52.0 bits (123), Expect = 7e-07
Identities = 51/193 (26%), Positives = 87/193 (45%), Gaps = 25/193 (12%)
Query: 93 CRDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRVIAHSSIQRI 152
C CA+V + G L SRQG ID + V R+N A +G+ RDVG +TS ++++
Sbjct: 148 CIRCAVVGNGGILNGSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNS 207
Query: 153 LRNRHDL--LNVSQGTVFIFWGPSSYMRRDGKGQVYNNLHLLSQVLP-------RLKAFM 203
L + +L +V QG + ++ D + V +L +P R A+
Sbjct: 208 LVSYWNLGFTSVPQGQDLQY----IFIPSDIRDYVMLRSAILGVPVPEGLDKGDRPHAYF 263
Query: 204 -----ITRHKMLQFDEL-FKQETGKDRKISNTWL------STGWFTMTIALELCDRINVY 251
++ K+L D + + E K+ NT STG + AL CD+++ Y
Sbjct: 264 GPEASASKFKLLHPDFISYLTERFLKSKLINTHFGDLYMPSTGALMLLTALHTCDQVSAY 323
Query: 252 GMVPPDFCRDPNH 264
G + ++ + +H
Sbjct: 324 GFITSNYWKFSDH 336
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.135 0.427
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,344,420
Number of Sequences: 37866
Number of extensions: 680982
Number of successful extensions: 7931
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 174
Number of HSP's successfully gapped in prelim test: 63
Number of HSP's that attempted gapping in prelim test: 4668
Number of HSP's gapped (non-prelim): 1620
length of query: 336
length of database: 18,247,518
effective HSP length: 103
effective length of query: 233
effective length of database: 14,347,320
effective search space: 3342925560
effective search space used: 3342925560
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.