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Search of human proteins with 60460887
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|60460887 solute carrier family 25, member 42 [Homo sapiens]
(318 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|60460887 solute carrier family 25, member 42 [Homo sapiens] 630 0.0
gi|27544933 solute carrier family 25, member 16 [Homo sapiens] 198 6e-51
gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo ... 181 8e-46
gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo s... 181 8e-46
gi|48476342 solute carrier family 25, member 23 [Homo sapiens] 176 2e-44
gi|239755176 PREDICTED: similar to solute carrier family 25, mem... 176 2e-44
gi|239755174 PREDICTED: similar to solute carrier family 25, mem... 176 2e-44
gi|56699407 solute carrier family 25, member 25 isoform c [Homo ... 176 2e-44
gi|56699401 solute carrier family 25, member 25 isoform a [Homo ... 176 2e-44
gi|56699405 solute carrier family 25, member 25 isoform d [Homo ... 176 2e-44
gi|56699403 solute carrier family 25, member 25 isoform b [Homo ... 176 2e-44
gi|149274607 solute carrier family 25, member 41 [Homo sapiens] 142 4e-34
gi|21687151 mitochondrial solute carrier protein [Homo sapiens] 126 2e-29
gi|55749577 solute carrier family 25 (mitochondrial carrier; ade... 120 1e-27
gi|186928856 solute carrier family 25, member 19 [Homo sapiens] 118 8e-27
gi|186928860 solute carrier family 25, member 19 [Homo sapiens] 118 8e-27
gi|186928858 solute carrier family 25, member 19 [Homo sapiens] 118 8e-27
gi|13775208 solute carrier family 25 (mitochondrial carrier; ade... 117 1e-26
gi|156071462 solute carrier family 25, member A6 [Homo sapiens] 114 1e-25
gi|156071459 solute carrier family 25, member 5 [Homo sapiens] 111 7e-25
gi|46094065 mitochondrial carrier family protein [Homo sapiens] 92 6e-19
gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo s... 90 3e-18
gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo... 90 3e-18
gi|58197562 solute carrier family 25, member 30 [Homo sapiens] 89 4e-18
gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens] 89 4e-18
gi|21361103 solute carrier family 25, member 12 [Homo sapiens] 85 1e-16
gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Ho... 83 3e-16
gi|13259543 solute carrier family 25, member 14 isoform UCP5S [H... 83 3e-16
gi|21314739 solute carrier family 25, member 32 [Homo sapiens] 81 1e-15
gi|21389315 solute carrier family 25 (mitochondrial carrier; cit... 79 4e-15
>gi|60460887 solute carrier family 25, member 42 [Homo sapiens]
Length = 318
Score = 630 bits (1625), Expect = 0.0
Identities = 318/318 (100%), Positives = 318/318 (100%)
Query: 1 MGNGVKEGPVRLHEDAEAVLSSSVSSKRDHRQVLSSLLPGALAGALAKTAVAPLDRTKII 60
MGNGVKEGPVRLHEDAEAVLSSSVSSKRDHRQVLSSLLPGALAGALAKTAVAPLDRTKII
Sbjct: 1 MGNGVKEGPVRLHEDAEAVLSSSVSSKRDHRQVLSSLLPGALAGALAKTAVAPLDRTKII 60
Query: 61 FQVSSKRFSAKEAFRVLYYTYLNEGFLSLWRGNSATMVRVVPYAAIQFSAHEEYKRILGS 120
FQVSSKRFSAKEAFRVLYYTYLNEGFLSLWRGNSATMVRVVPYAAIQFSAHEEYKRILGS
Sbjct: 61 FQVSSKRFSAKEAFRVLYYTYLNEGFLSLWRGNSATMVRVVPYAAIQFSAHEEYKRILGS 120
Query: 121 YYGFRGEALPPWPRLFAGALAGTTAASLTYPLDLVRARMAVTPKEMYSNIFHVFIRISRE 180
YYGFRGEALPPWPRLFAGALAGTTAASLTYPLDLVRARMAVTPKEMYSNIFHVFIRISRE
Sbjct: 121 YYGFRGEALPPWPRLFAGALAGTTAASLTYPLDLVRARMAVTPKEMYSNIFHVFIRISRE 180
Query: 181 EGLKTLYHGFMPTVLGVIPYAGLSFFTYETLKSLHREYSGRRQPYPFERMIFGACAGLIG 240
EGLKTLYHGFMPTVLGVIPYAGLSFFTYETLKSLHREYSGRRQPYPFERMIFGACAGLIG
Sbjct: 181 EGLKTLYHGFMPTVLGVIPYAGLSFFTYETLKSLHREYSGRRQPYPFERMIFGACAGLIG 240
Query: 241 QSASYPLDVVRRRMQTAGVTGYPRASIARTLRTIVREEGAVRGLYKGLSMNWVKGPIAVG 300
QSASYPLDVVRRRMQTAGVTGYPRASIARTLRTIVREEGAVRGLYKGLSMNWVKGPIAVG
Sbjct: 241 QSASYPLDVVRRRMQTAGVTGYPRASIARTLRTIVREEGAVRGLYKGLSMNWVKGPIAVG 300
Query: 301 ISFTTFDLMQIMLRHLQS 318
ISFTTFDLMQIMLRHLQS
Sbjct: 301 ISFTTFDLMQIMLRHLQS 318
>gi|27544933 solute carrier family 25, member 16 [Homo sapiens]
Length = 332
Score = 198 bits (503), Expect = 6e-51
Identities = 117/294 (39%), Positives = 164/294 (55%), Gaps = 21/294 (7%)
Query: 34 LSSLLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYLNEGFLSLWRGN 93
L S L G +AG AKT VAPLDR K++ Q + + F L EGFL L++GN
Sbjct: 37 LRSFLAGGIAGCCAKTTVAPLDRVKVLLQAHNHHYKHLGVFSALRAVPQKEGFLGLYKGN 96
Query: 94 SATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALAGTTAASLTYPLD 153
A M+R+ PY AIQF A E YK ++ + G G RL AG++AG TA TYPLD
Sbjct: 97 GAMMIRIFPYGAIQFMAFEHYKTLITTKLGISGHV----HRLMAGSMAGMTAVICTYPLD 152
Query: 154 LVRARMA--VTPKEMYSNIFHVFIRI-SREEGLKTLYHGFMPTVLGVIPYAGLSFFTYET 210
+VR R+A V + Y+ I H F I ++E G Y G MPT+LG+ PYAG+SFFT+ T
Sbjct: 153 MVRVRLAFQVKGEHSYTGIIHAFKTIYAKEGGFFGFYRGLMPTILGMAPYAGVSFFTFGT 212
Query: 211 LKSLHREYSGRRQPYPFE------------RMIFGACAGLIGQSASYPLDVVRRRMQTAG 258
LKS+ ++ P ++ G AG I Q+ SYP DV RRRMQ
Sbjct: 213 LKSVGLSHAPTLLGRPSSDNPNVLVLKTHVNLLCGGVAGAIAQTISYPFDVTRRRMQLGT 272
Query: 259 V-TGYPRASIAR-TLRTIVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFDLMQ 310
V + + R T++ + G +GLY+GLS+N+++ + ++FTT++LM+
Sbjct: 273 VLPEFEKCLTMRDTMKYVYGHHGIRKGLYRGLSLNYIRCIPSQAVAFTTYELMK 326
>gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo
sapiens]
Length = 477
Score = 181 bits (459), Expect = 8e-46
Identities = 100/277 (36%), Positives = 160/277 (57%), Gaps = 8/277 (2%)
Query: 37 LLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYLNEGFLSLWRGNSAT 96
LL G +AGA+++T+ APLDR KI+ QV + F G SLWRGN
Sbjct: 198 LLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTN 257
Query: 97 MVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALAGTTAASLTYPLDLVR 156
++++ P A++F A+E+YK++L G+ + + R +G++AG TA + YP+++++
Sbjct: 258 VIKIAPETAVKFWAYEQYKKLLTE----EGQKIGTFERFISGSMAGATAQTFIYPMEVMK 313
Query: 157 ARMAVTPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTYETLKSLHR 216
R+AV YS I+ +I + EGL Y G++P +LG+IPYAG+ YE LKS
Sbjct: 314 TRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWL 373
Query: 217 EYSGRRQPYPFERMIF--GACAGLIGQSASYPLDVVRRRMQT-AGVTGYPRASIARTLRT 273
+ + P ++ GA + GQ ASYPL +VR RMQ A + G P+ ++ R
Sbjct: 374 DNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRR 433
Query: 274 IVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFDLMQ 310
I+ +EG + GLY+G++ N++K AVGIS+ ++ M+
Sbjct: 434 IISKEG-IPGLYRGITPNFMKVLPAVGISYVVYENMK 469
Score = 75.5 bits (184), Expect = 6e-14
Identities = 55/180 (30%), Positives = 91/180 (50%), Gaps = 6/180 (3%)
Query: 132 WPRLFAGALAGTTAASLTYPLDLVRARMAV-TPKEMYSNIFHVFIRISREEGLKTLYHGF 190
W +L AG +AG + + T PLD ++ M V K NIF F ++ +E G+++L+ G
Sbjct: 195 WRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGN 254
Query: 191 MPTVLGVIPYAGLSFFTYETLKSLHREYSGRRQPYPFERMIFGACAGLIGQSASYPLDVV 250
V+ + P + F+ YE K L E ++ FER I G+ AG Q+ YP++V+
Sbjct: 255 GTNVIKIAPETAVKFWAYEQYKKLLTEEG--QKIGTFERFISGSMAGATAQTFIYPMEVM 312
Query: 251 RRRMQTAGVTGYPRASIARTLRTIVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFDLMQ 310
+ R+ G TG + I + I++ EG + YKG N + GI ++L++
Sbjct: 313 KTRL-AVGKTG-QYSGIYDCAKKILKHEG-LGAFYKGYVPNLLGIIPYAGIDLAVYELLK 369
Score = 29.6 bits (65), Expect = 3.7
Identities = 20/82 (24%), Positives = 36/82 (43%), Gaps = 2/82 (2%)
Query: 40 GALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYL--NEGFLSLWRGNSATM 97
GAL+ + A PL + Q + + + V + + EG L+RG +
Sbjct: 392 GALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNF 451
Query: 98 VRVVPYAAIQFSAHEEYKRILG 119
++V+P I + +E K+ LG
Sbjct: 452 MKVLPAVGISYVVYENMKQTLG 473
>gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo
sapiens]
Length = 458
Score = 181 bits (459), Expect = 8e-46
Identities = 100/277 (36%), Positives = 160/277 (57%), Gaps = 8/277 (2%)
Query: 37 LLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYLNEGFLSLWRGNSAT 96
LL G +AGA+++T+ APLDR KI+ QV + F G SLWRGN
Sbjct: 179 LLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTN 238
Query: 97 MVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALAGTTAASLTYPLDLVR 156
++++ P A++F A+E+YK++L G+ + + R +G++AG TA + YP+++++
Sbjct: 239 VIKIAPETAVKFWAYEQYKKLLTE----EGQKIGTFERFISGSMAGATAQTFIYPMEVMK 294
Query: 157 ARMAVTPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTYETLKSLHR 216
R+AV YS I+ +I + EGL Y G++P +LG+IPYAG+ YE LKS
Sbjct: 295 TRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWL 354
Query: 217 EYSGRRQPYPFERMIF--GACAGLIGQSASYPLDVVRRRMQT-AGVTGYPRASIARTLRT 273
+ + P ++ GA + GQ ASYPL +VR RMQ A + G P+ ++ R
Sbjct: 355 DNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRR 414
Query: 274 IVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFDLMQ 310
I+ +EG + GLY+G++ N++K AVGIS+ ++ M+
Sbjct: 415 IISKEG-IPGLYRGITPNFMKVLPAVGISYVVYENMK 450
Score = 75.5 bits (184), Expect = 6e-14
Identities = 55/180 (30%), Positives = 91/180 (50%), Gaps = 6/180 (3%)
Query: 132 WPRLFAGALAGTTAASLTYPLDLVRARMAV-TPKEMYSNIFHVFIRISREEGLKTLYHGF 190
W +L AG +AG + + T PLD ++ M V K NIF F ++ +E G+++L+ G
Sbjct: 176 WRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGN 235
Query: 191 MPTVLGVIPYAGLSFFTYETLKSLHREYSGRRQPYPFERMIFGACAGLIGQSASYPLDVV 250
V+ + P + F+ YE K L E ++ FER I G+ AG Q+ YP++V+
Sbjct: 236 GTNVIKIAPETAVKFWAYEQYKKLLTEEG--QKIGTFERFISGSMAGATAQTFIYPMEVM 293
Query: 251 RRRMQTAGVTGYPRASIARTLRTIVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFDLMQ 310
+ R+ G TG + I + I++ EG + YKG N + GI ++L++
Sbjct: 294 KTRL-AVGKTG-QYSGIYDCAKKILKHEG-LGAFYKGYVPNLLGIIPYAGIDLAVYELLK 350
Score = 29.6 bits (65), Expect = 3.7
Identities = 20/82 (24%), Positives = 36/82 (43%), Gaps = 2/82 (2%)
Query: 40 GALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYL--NEGFLSLWRGNSATM 97
GAL+ + A PL + Q + + + V + + EG L+RG +
Sbjct: 373 GALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNF 432
Query: 98 VRVVPYAAIQFSAHEEYKRILG 119
++V+P I + +E K+ LG
Sbjct: 433 MKVLPAVGISYVVYENMKQTLG 454
>gi|48476342 solute carrier family 25, member 23 [Homo sapiens]
Length = 468
Score = 176 bits (447), Expect = 2e-44
Identities = 105/278 (37%), Positives = 158/278 (56%), Gaps = 10/278 (3%)
Query: 37 LLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYLNEGFLSLWRGNSAT 96
L+ GA+AGA+++T APLDR K+ QV + + + L L G SLWRGN
Sbjct: 189 LVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLNILGGLRSMVLEGGIRSLWRGNGIN 248
Query: 97 MVRVVPYAAIQFSAHEEYKR-ILGSYYGFRGEALPPWPRLFAGALAGTTAASLTYPLDLV 155
++++ P +AI+F A+E+ KR ILG E L R AG+LAG TA ++ YP++++
Sbjct: 249 VLKIAPESAIKFMAYEQIKRAILGQQ-----ETLHVQERFVAGSLAGATAQTIIYPMEVL 303
Query: 156 RARMAVTPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTYETLKS-- 213
+ R+ + Y + RI EG + Y G++P VLG+IPYAG+ YETLK+
Sbjct: 304 KTRLTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETLKNWW 363
Query: 214 LHREYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVRRRMQT-AGVTGYPRASIARTLR 272
L + P + G + GQ ASYPL +VR RMQ A + G P+ S+ LR
Sbjct: 364 LQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASIEGGPQLSMLGLLR 423
Query: 273 TIVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFDLMQ 310
I+ +EG +RGLY+G++ N++K AV IS+ ++ M+
Sbjct: 424 HILSQEG-MRGLYRGIAPNFMKVIPAVSISYVVYENMK 460
Score = 65.9 bits (159), Expect = 5e-11
Identities = 48/198 (24%), Positives = 89/198 (44%), Gaps = 8/198 (4%)
Query: 20 LSSSVSSKRDHRQVLSSLLPGALAGALAKTAVAPLD--RTKIIFQVSSKRFSAKEAFRVL 77
+ ++ +++ V + G+LAGA A+T + P++ +T++ + + + + R +
Sbjct: 266 IKRAILGQQETLHVQERFVAGSLAGATAQTIIYPMEVLKTRLTLRRTGQYKGLLDCARRI 325
Query: 78 YYTYLNEGFLSLWRGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFA 137
EG + +RG ++ ++PYA I + +E K Y L
Sbjct: 326 LE---REGPRAFYRGYLPNVLGIIPYAGIDLAVYETLKNWWLQQYSHDSADPGILVLLAC 382
Query: 138 GALAGTTAASLTYPLDLVRARM---AVTPKEMYSNIFHVFIRISREEGLKTLYHGFMPTV 194
G ++ T +YPL LVR RM A ++ + I +EG++ LY G P
Sbjct: 383 GTISSTCGQIASYPLALVRTRMQAQASIEGGPQLSMLGLLRHILSQEGMRGLYRGIAPNF 442
Query: 195 LGVIPYAGLSFFTYETLK 212
+ VIP +S+ YE +K
Sbjct: 443 MKVIPAVSISYVVYENMK 460
Score = 63.2 bits (152), Expect = 3e-10
Identities = 51/181 (28%), Positives = 87/181 (48%), Gaps = 8/181 (4%)
Query: 132 WPRLFAGALAGTTAASLTYPLDLVRARMAV-TPKEMYSNIFHVFIRISREEGLKTLYHGF 190
W +L AGA+AG + + T PLD ++ M V K NI + E G+++L+ G
Sbjct: 186 WKQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLNILGGLRSMVLEGGIRSLWRGN 245
Query: 191 MPTVLGVIPYAGLSFFTYETLKSLHREYSGRRQP-YPFERMIFGACAGLIGQSASYPLDV 249
VL + P + + F YE +K R G+++ + ER + G+ AG Q+ YP++V
Sbjct: 246 GINVLKIAPESAIKFMAYEQIK---RAILGQQETLHVQERFVAGSLAGATAQTIIYPMEV 302
Query: 250 VRRRMQTAGVTGYPRASIARTLRTIVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFDLM 309
++ R+ T TG + + R + RE R Y+G N + GI ++ +
Sbjct: 303 LKTRL-TLRRTGQYKGLLDCARRILERE--GPRAFYRGYLPNVLGIIPYAGIDLAVYETL 359
Query: 310 Q 310
+
Sbjct: 360 K 360
Score = 34.3 bits (77), Expect = 0.15
Identities = 23/89 (25%), Positives = 41/89 (46%), Gaps = 2/89 (2%)
Query: 33 VLSSLLPGALAGALAKTAVAPLD--RTKIIFQVSSKRFSAKEAFRVLYYTYLNEGFLSLW 90
+L L G ++ + A PL RT++ Q S + +L + EG L+
Sbjct: 376 ILVLLACGTISSTCGQIASYPLALVRTRMQAQASIEGGPQLSMLGLLRHILSQEGMRGLY 435
Query: 91 RGNSATMVRVVPYAAIQFSAHEEYKRILG 119
RG + ++V+P +I + +E K+ LG
Sbjct: 436 RGIAPNFMKVIPAVSISYVVYENMKQALG 464
>gi|239755176 PREDICTED: similar to solute carrier family 25, member
25 isoform 2 [Homo sapiens]
Length = 469
Score = 176 bits (446), Expect = 2e-44
Identities = 106/280 (37%), Positives = 157/280 (56%), Gaps = 8/280 (2%)
Query: 37 LLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYLNEGFLSLWRGNSAT 96
L+ G AGA+++T APLDR K++ QV + R + G SLWRGN
Sbjct: 190 LVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGIN 249
Query: 97 MVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALAGTTAASLTYPLDLVR 156
++++ P +AI+F A+E+ KR++GS E L RL AG+LAG A S YP+++++
Sbjct: 250 VLKIAPESAIKFMAYEQIKRLVGSDQ----ETLRIHERLVAGSLAGAIAQSSIYPMEVLK 305
Query: 157 ARMAVTPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTYETLKS--L 214
RMA+ YS + RI EG+ Y G++P +LG+IPYAG+ YETLK+ L
Sbjct: 306 TRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWL 365
Query: 215 HREYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVRRRMQT-AGVTGYPRASIARTLRT 273
P F + G + GQ ASYPL +VR RMQ A + G P +++ +
Sbjct: 366 QHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKH 425
Query: 274 IVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFDLMQIML 313
I+R EGA GLY+GL+ N++K AV IS+ ++ ++I L
Sbjct: 426 ILRTEGAF-GLYRGLAPNFMKVIPAVSISYVVYENLKITL 464
Score = 77.8 bits (190), Expect = 1e-14
Identities = 53/197 (26%), Positives = 93/197 (47%), Gaps = 14/197 (7%)
Query: 24 VSSKRDHRQVLSSLLPGALAGALAKTAVAPLD--RTKIIFQVSSKRFSAKEAFRVLYYTY 81
V S ++ ++ L+ G+LAGA+A++++ P++ +T++ + + + + R +
Sbjct: 271 VGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRI---L 327
Query: 82 LNEGFLSLWRGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALA 141
EG + ++G M+ ++PYA I + +E K +Y + L G ++
Sbjct: 328 AREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMS 387
Query: 142 GTTAASLTYPLDLVRARMAV------TPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVL 195
T +YPL LVR RM P+ S++F I R EG LY G P +
Sbjct: 388 STCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFK---HILRTEGAFGLYRGLAPNFM 444
Query: 196 GVIPYAGLSFFTYETLK 212
VIP +S+ YE LK
Sbjct: 445 KVIPAVSISYVVYENLK 461
Score = 30.4 bits (67), Expect = 2.2
Identities = 19/82 (23%), Positives = 35/82 (42%), Gaps = 2/82 (2%)
Query: 40 GALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYL--NEGFLSLWRGNSATM 97
G ++ + A PL + Q + A E + ++ EG L+RG +
Sbjct: 384 GTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNF 443
Query: 98 VRVVPYAAIQFSAHEEYKRILG 119
++V+P +I + +E K LG
Sbjct: 444 MKVIPAVSISYVVYENLKITLG 465
>gi|239755174 PREDICTED: similar to solute carrier family 25, member
25 isoform 1 [Homo sapiens]
Length = 503
Score = 176 bits (446), Expect = 2e-44
Identities = 106/280 (37%), Positives = 157/280 (56%), Gaps = 8/280 (2%)
Query: 37 LLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYLNEGFLSLWRGNSAT 96
L+ G AGA+++T APLDR K++ QV + R + G SLWRGN
Sbjct: 224 LVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGIN 283
Query: 97 MVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALAGTTAASLTYPLDLVR 156
++++ P +AI+F A+E+ KR++GS E L RL AG+LAG A S YP+++++
Sbjct: 284 VLKIAPESAIKFMAYEQIKRLVGSDQ----ETLRIHERLVAGSLAGAIAQSSIYPMEVLK 339
Query: 157 ARMAVTPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTYETLKS--L 214
RMA+ YS + RI EG+ Y G++P +LG+IPYAG+ YETLK+ L
Sbjct: 340 TRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWL 399
Query: 215 HREYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVRRRMQT-AGVTGYPRASIARTLRT 273
P F + G + GQ ASYPL +VR RMQ A + G P +++ +
Sbjct: 400 QHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKH 459
Query: 274 IVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFDLMQIML 313
I+R EGA GLY+GL+ N++K AV IS+ ++ ++I L
Sbjct: 460 ILRTEGAF-GLYRGLAPNFMKVIPAVSISYVVYENLKITL 498
Score = 77.8 bits (190), Expect = 1e-14
Identities = 53/197 (26%), Positives = 93/197 (47%), Gaps = 14/197 (7%)
Query: 24 VSSKRDHRQVLSSLLPGALAGALAKTAVAPLD--RTKIIFQVSSKRFSAKEAFRVLYYTY 81
V S ++ ++ L+ G+LAGA+A++++ P++ +T++ + + + + R +
Sbjct: 305 VGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRI---L 361
Query: 82 LNEGFLSLWRGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALA 141
EG + ++G M+ ++PYA I + +E K +Y + L G ++
Sbjct: 362 AREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMS 421
Query: 142 GTTAASLTYPLDLVRARMAV------TPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVL 195
T +YPL LVR RM P+ S++F I R EG LY G P +
Sbjct: 422 STCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFK---HILRTEGAFGLYRGLAPNFM 478
Query: 196 GVIPYAGLSFFTYETLK 212
VIP +S+ YE LK
Sbjct: 479 KVIPAVSISYVVYENLK 495
Score = 30.4 bits (67), Expect = 2.2
Identities = 19/82 (23%), Positives = 35/82 (42%), Gaps = 2/82 (2%)
Query: 40 GALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYL--NEGFLSLWRGNSATM 97
G ++ + A PL + Q + A E + ++ EG L+RG +
Sbjct: 418 GTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNF 477
Query: 98 VRVVPYAAIQFSAHEEYKRILG 119
++V+P +I + +E K LG
Sbjct: 478 MKVIPAVSISYVVYENLKITLG 499
>gi|56699407 solute carrier family 25, member 25 isoform c [Homo
sapiens]
Length = 489
Score = 176 bits (446), Expect = 2e-44
Identities = 106/280 (37%), Positives = 157/280 (56%), Gaps = 8/280 (2%)
Query: 37 LLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYLNEGFLSLWRGNSAT 96
L+ G AGA+++T APLDR K++ QV + R + G SLWRGN
Sbjct: 210 LVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGIN 269
Query: 97 MVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALAGTTAASLTYPLDLVR 156
++++ P +AI+F A+E+ KR++GS E L RL AG+LAG A S YP+++++
Sbjct: 270 VLKIAPESAIKFMAYEQIKRLVGSDQ----ETLRIHERLVAGSLAGAIAQSSIYPMEVLK 325
Query: 157 ARMAVTPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTYETLKS--L 214
RMA+ YS + RI EG+ Y G++P +LG+IPYAG+ YETLK+ L
Sbjct: 326 TRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWL 385
Query: 215 HREYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVRRRMQT-AGVTGYPRASIARTLRT 273
P F + G + GQ ASYPL +VR RMQ A + G P +++ +
Sbjct: 386 QHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKH 445
Query: 274 IVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFDLMQIML 313
I+R EGA GLY+GL+ N++K AV IS+ ++ ++I L
Sbjct: 446 ILRTEGAF-GLYRGLAPNFMKVIPAVSISYVVYENLKITL 484
Score = 77.8 bits (190), Expect = 1e-14
Identities = 53/197 (26%), Positives = 93/197 (47%), Gaps = 14/197 (7%)
Query: 24 VSSKRDHRQVLSSLLPGALAGALAKTAVAPLD--RTKIIFQVSSKRFSAKEAFRVLYYTY 81
V S ++ ++ L+ G+LAGA+A++++ P++ +T++ + + + + R +
Sbjct: 291 VGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRI---L 347
Query: 82 LNEGFLSLWRGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALA 141
EG + ++G M+ ++PYA I + +E K +Y + L G ++
Sbjct: 348 AREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMS 407
Query: 142 GTTAASLTYPLDLVRARMAV------TPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVL 195
T +YPL LVR RM P+ S++F I R EG LY G P +
Sbjct: 408 STCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFK---HILRTEGAFGLYRGLAPNFM 464
Query: 196 GVIPYAGLSFFTYETLK 212
VIP +S+ YE LK
Sbjct: 465 KVIPAVSISYVVYENLK 481
Score = 30.4 bits (67), Expect = 2.2
Identities = 19/82 (23%), Positives = 35/82 (42%), Gaps = 2/82 (2%)
Query: 40 GALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYL--NEGFLSLWRGNSATM 97
G ++ + A PL + Q + A E + ++ EG L+RG +
Sbjct: 404 GTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNF 463
Query: 98 VRVVPYAAIQFSAHEEYKRILG 119
++V+P +I + +E K LG
Sbjct: 464 MKVIPAVSISYVVYENLKITLG 485
>gi|56699401 solute carrier family 25, member 25 isoform a [Homo
sapiens]
Length = 469
Score = 176 bits (446), Expect = 2e-44
Identities = 106/280 (37%), Positives = 157/280 (56%), Gaps = 8/280 (2%)
Query: 37 LLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYLNEGFLSLWRGNSAT 96
L+ G AGA+++T APLDR K++ QV + R + G SLWRGN
Sbjct: 190 LVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGIN 249
Query: 97 MVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALAGTTAASLTYPLDLVR 156
++++ P +AI+F A+E+ KR++GS E L RL AG+LAG A S YP+++++
Sbjct: 250 VLKIAPESAIKFMAYEQIKRLVGSDQ----ETLRIHERLVAGSLAGAIAQSSIYPMEVLK 305
Query: 157 ARMAVTPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTYETLKS--L 214
RMA+ YS + RI EG+ Y G++P +LG+IPYAG+ YETLK+ L
Sbjct: 306 TRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWL 365
Query: 215 HREYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVRRRMQT-AGVTGYPRASIARTLRT 273
P F + G + GQ ASYPL +VR RMQ A + G P +++ +
Sbjct: 366 QHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKH 425
Query: 274 IVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFDLMQIML 313
I+R EGA GLY+GL+ N++K AV IS+ ++ ++I L
Sbjct: 426 ILRTEGAF-GLYRGLAPNFMKVIPAVSISYVVYENLKITL 464
Score = 77.8 bits (190), Expect = 1e-14
Identities = 53/197 (26%), Positives = 93/197 (47%), Gaps = 14/197 (7%)
Query: 24 VSSKRDHRQVLSSLLPGALAGALAKTAVAPLD--RTKIIFQVSSKRFSAKEAFRVLYYTY 81
V S ++ ++ L+ G+LAGA+A++++ P++ +T++ + + + + R +
Sbjct: 271 VGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRI---L 327
Query: 82 LNEGFLSLWRGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALA 141
EG + ++G M+ ++PYA I + +E K +Y + L G ++
Sbjct: 328 AREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMS 387
Query: 142 GTTAASLTYPLDLVRARMAV------TPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVL 195
T +YPL LVR RM P+ S++F I R EG LY G P +
Sbjct: 388 STCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFK---HILRTEGAFGLYRGLAPNFM 444
Query: 196 GVIPYAGLSFFTYETLK 212
VIP +S+ YE LK
Sbjct: 445 KVIPAVSISYVVYENLK 461
Score = 30.4 bits (67), Expect = 2.2
Identities = 19/82 (23%), Positives = 35/82 (42%), Gaps = 2/82 (2%)
Query: 40 GALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYL--NEGFLSLWRGNSATM 97
G ++ + A PL + Q + A E + ++ EG L+RG +
Sbjct: 384 GTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNF 443
Query: 98 VRVVPYAAIQFSAHEEYKRILG 119
++V+P +I + +E K LG
Sbjct: 444 MKVIPAVSISYVVYENLKITLG 465
>gi|56699405 solute carrier family 25, member 25 isoform d [Homo
sapiens]
Length = 366
Score = 176 bits (446), Expect = 2e-44
Identities = 106/280 (37%), Positives = 157/280 (56%), Gaps = 8/280 (2%)
Query: 37 LLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYLNEGFLSLWRGNSAT 96
L+ G AGA+++T APLDR K++ QV + R + G SLWRGN
Sbjct: 87 LVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGIN 146
Query: 97 MVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALAGTTAASLTYPLDLVR 156
++++ P +AI+F A+E+ KR++GS E L RL AG+LAG A S YP+++++
Sbjct: 147 VLKIAPESAIKFMAYEQIKRLVGSDQ----ETLRIHERLVAGSLAGAIAQSSIYPMEVLK 202
Query: 157 ARMAVTPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTYETLKS--L 214
RMA+ YS + RI EG+ Y G++P +LG+IPYAG+ YETLK+ L
Sbjct: 203 TRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWL 262
Query: 215 HREYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVRRRMQT-AGVTGYPRASIARTLRT 273
P F + G + GQ ASYPL +VR RMQ A + G P +++ +
Sbjct: 263 QHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKH 322
Query: 274 IVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFDLMQIML 313
I+R EGA GLY+GL+ N++K AV IS+ ++ ++I L
Sbjct: 323 ILRTEGAF-GLYRGLAPNFMKVIPAVSISYVVYENLKITL 361
Score = 77.8 bits (190), Expect = 1e-14
Identities = 53/197 (26%), Positives = 93/197 (47%), Gaps = 14/197 (7%)
Query: 24 VSSKRDHRQVLSSLLPGALAGALAKTAVAPLD--RTKIIFQVSSKRFSAKEAFRVLYYTY 81
V S ++ ++ L+ G+LAGA+A++++ P++ +T++ + + + + R +
Sbjct: 168 VGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRI---L 224
Query: 82 LNEGFLSLWRGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALA 141
EG + ++G M+ ++PYA I + +E K +Y + L G ++
Sbjct: 225 AREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMS 284
Query: 142 GTTAASLTYPLDLVRARMAV------TPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVL 195
T +YPL LVR RM P+ S++F I R EG LY G P +
Sbjct: 285 STCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFK---HILRTEGAFGLYRGLAPNFM 341
Query: 196 GVIPYAGLSFFTYETLK 212
VIP +S+ YE LK
Sbjct: 342 KVIPAVSISYVVYENLK 358
Score = 30.4 bits (67), Expect = 2.2
Identities = 19/82 (23%), Positives = 35/82 (42%), Gaps = 2/82 (2%)
Query: 40 GALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYL--NEGFLSLWRGNSATM 97
G ++ + A PL + Q + A E + ++ EG L+RG +
Sbjct: 281 GTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNF 340
Query: 98 VRVVPYAAIQFSAHEEYKRILG 119
++V+P +I + +E K LG
Sbjct: 341 MKVIPAVSISYVVYENLKITLG 362
>gi|56699403 solute carrier family 25, member 25 isoform b [Homo
sapiens]
Length = 503
Score = 176 bits (446), Expect = 2e-44
Identities = 106/280 (37%), Positives = 157/280 (56%), Gaps = 8/280 (2%)
Query: 37 LLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYLNEGFLSLWRGNSAT 96
L+ G AGA+++T APLDR K++ QV + R + G SLWRGN
Sbjct: 224 LVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGIN 283
Query: 97 MVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALAGTTAASLTYPLDLVR 156
++++ P +AI+F A+E+ KR++GS E L RL AG+LAG A S YP+++++
Sbjct: 284 VLKIAPESAIKFMAYEQIKRLVGSDQ----ETLRIHERLVAGSLAGAIAQSSIYPMEVLK 339
Query: 157 ARMAVTPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTYETLKS--L 214
RMA+ YS + RI EG+ Y G++P +LG+IPYAG+ YETLK+ L
Sbjct: 340 TRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWL 399
Query: 215 HREYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVRRRMQT-AGVTGYPRASIARTLRT 273
P F + G + GQ ASYPL +VR RMQ A + G P +++ +
Sbjct: 400 QHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKH 459
Query: 274 IVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFDLMQIML 313
I+R EGA GLY+GL+ N++K AV IS+ ++ ++I L
Sbjct: 460 ILRTEGAF-GLYRGLAPNFMKVIPAVSISYVVYENLKITL 498
Score = 77.8 bits (190), Expect = 1e-14
Identities = 53/197 (26%), Positives = 93/197 (47%), Gaps = 14/197 (7%)
Query: 24 VSSKRDHRQVLSSLLPGALAGALAKTAVAPLD--RTKIIFQVSSKRFSAKEAFRVLYYTY 81
V S ++ ++ L+ G+LAGA+A++++ P++ +T++ + + + + R +
Sbjct: 305 VGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRI---L 361
Query: 82 LNEGFLSLWRGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALA 141
EG + ++G M+ ++PYA I + +E K +Y + L G ++
Sbjct: 362 AREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMS 421
Query: 142 GTTAASLTYPLDLVRARMAV------TPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVL 195
T +YPL LVR RM P+ S++F I R EG LY G P +
Sbjct: 422 STCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFK---HILRTEGAFGLYRGLAPNFM 478
Query: 196 GVIPYAGLSFFTYETLK 212
VIP +S+ YE LK
Sbjct: 479 KVIPAVSISYVVYENLK 495
Score = 30.4 bits (67), Expect = 2.2
Identities = 19/82 (23%), Positives = 35/82 (42%), Gaps = 2/82 (2%)
Query: 40 GALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYL--NEGFLSLWRGNSATM 97
G ++ + A PL + Q + A E + ++ EG L+RG +
Sbjct: 418 GTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNF 477
Query: 98 VRVVPYAAIQFSAHEEYKRILG 119
++V+P +I + +E K LG
Sbjct: 478 MKVIPAVSISYVVYENLKITLG 499
>gi|149274607 solute carrier family 25, member 41 [Homo sapiens]
Length = 370
Score = 142 bits (358), Expect = 4e-34
Identities = 94/286 (32%), Positives = 152/286 (53%), Gaps = 11/286 (3%)
Query: 29 DHRQVL-SSLLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYLNEGFL 87
D+++ L LL GA+AGA+++T APLDR K+ QV S + + L GF
Sbjct: 87 DNKEALWKFLLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTNFTNLLGGLQSMVQEGGFR 146
Query: 88 SLWRGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPW-PRLFAGALAGTTAA 146
SLWRGN ++++ P AI+FS E+ K + G +G PP+ RL AG+LA +
Sbjct: 147 SLWRGNGINVLKIAPEYAIKFSVFEQCKNY---FCGIQGS--PPFQERLLAGSLAVAISQ 201
Query: 147 SLTYPLDLVRARMAVTPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFF 206
+L P+++++ R+ + Y + +I + EG + LY G++P +LG+IPYA
Sbjct: 202 TLINPMEVLKTRLTLRRTGQYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYACTDLA 261
Query: 207 TYETLKSLHREYSGRRQPYPFERMIFGA--CAGLIGQSASYPLDVVRRRMQTAGVTGYPR 264
YE L+ + SGR P + + + GQ ASYPL +VR RMQ
Sbjct: 262 VYEMLQCFWVK-SGRDMGDPSGLVSLSSVTLSTTCGQMASYPLTLVRTRMQAQDTVEGSN 320
Query: 265 ASIARTLRTIVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFDLMQ 310
++ L+ I+ ++G + GLY+G++ +K A GIS+ ++ M+
Sbjct: 321 PTMRGVLQRILAQQGWL-GLYRGMTPTLLKVLPAGGISYVVYEAMK 365
Score = 35.0 bits (79), Expect = 0.088
Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 1/87 (1%)
Query: 34 LSSLLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFR-VLYYTYLNEGFLSLWRG 92
L SL L+ + A PL + Q + R VL +G+L L+RG
Sbjct: 283 LVSLSSVTLSTTCGQMASYPLTLVRTRMQAQDTVEGSNPTMRGVLQRILAQQGWLGLYRG 342
Query: 93 NSATMVRVVPYAAIQFSAHEEYKRILG 119
+ T+++V+P I + +E K+ LG
Sbjct: 343 MTPTLLKVLPAGGISYVVYEAMKKTLG 369
>gi|21687151 mitochondrial solute carrier protein [Homo sapiens]
Length = 341
Score = 126 bits (317), Expect = 2e-29
Identities = 81/281 (28%), Positives = 140/281 (49%), Gaps = 18/281 (6%)
Query: 37 LLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYLNEGFLSLWRGNSAT 96
LL LAG L+ + APL+ ++ QV R A+ + + + EG +LW+GN+
Sbjct: 16 LLCAGLAGTLSLSLTAPLELATVLAQVGVVRGHARGPWATGHRVWRAEGLRALWKGNAVA 75
Query: 97 MVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALAGTTAASLTYPLDLVR 156
+R+ P +A+Q +A+ ++ + G + W + AG+LAG + +TYP DL++
Sbjct: 76 CLRLFPCSAVQLAAYRKFVVLFTDDLGH----ISQWSSIMAGSLAGMVSTIVTYPTDLIK 131
Query: 157 ARMAVTP--KEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTYETLKSL 214
R+ + + Y + H F I ++EG LY G TV+G +P++ S Y L+ +
Sbjct: 132 TRLIMQNILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAGSLLVYMNLEKI 191
Query: 215 HREYSGRRQPYPFERMIFGAC-AGLIGQSASYPLDVVRRRMQT-------AGVTGYPRAS 266
++G R + + C A + Q+ S+P + V+R+MQ +G +
Sbjct: 192 ---WNGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSG 248
Query: 267 IARTLRTIVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFD 307
R IV+ +G V GL+ GL+ N +K GI F+TF+
Sbjct: 249 AVDCFRQIVKAQG-VLGLWNGLTANLLKIVPYFGIMFSTFE 288
Score = 65.9 bits (159), Expect = 5e-11
Identities = 52/197 (26%), Positives = 94/197 (47%), Gaps = 18/197 (9%)
Query: 30 HRQVLSSLLPGALAGALAKTAVAPLD--RTKIIFQVSSKRFSAKEAFRVLYYTYLNEGFL 87
H SS++ G+LAG ++ P D +T++I Q + S + Y EGFL
Sbjct: 103 HISQWSSIMAGSLAGMVSTIVTYPTDLIKTRLIMQ-NILEPSYRGLLHAFSTIYQQEGFL 161
Query: 88 SLWRGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGA-LAGTTAA 146
+L+RG S T+V +P++A + ++I + G R + P+ FA LA
Sbjct: 162 ALYRGVSLTVVGALPFSAGSLLVYMNLEKI---WNGPRDQF--SLPQNFANVCLAAAVTQ 216
Query: 147 SLTYPLDLVRARMAVTPKEM---------YSNIFHVFIRISREEGLKTLYHGFMPTVLGV 197
+L++P + V+ +M + +S F +I + +G+ L++G +L +
Sbjct: 217 TLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKI 276
Query: 198 IPYAGLSFFTYETLKSL 214
+PY G+ F T+E K +
Sbjct: 277 VPYFGIMFSTFEFCKRI 293
Score = 55.5 bits (132), Expect = 6e-08
Identities = 47/181 (25%), Positives = 82/181 (45%), Gaps = 7/181 (3%)
Query: 134 RLFAGALAGTTAASLTYPLDL--VRARMAVTPKEMYSNIFHVFIRISREEGLKTLYHGFM 191
RL LAGT + SLT PL+L V A++ V + + R+ R EGL+ L+ G
Sbjct: 15 RLLCAGLAGTLSLSLTAPLELATVLAQVGVV-RGHARGPWATGHRVWRAEGLRALWKGNA 73
Query: 192 PTVLGVIPYAGLSFFTYETLKSLHREYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVR 251
L + P + + Y L + G + ++ G+ AG++ +YP D+++
Sbjct: 74 VACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQW--SSIMAGSLAGMVSTIVTYPTDLIK 131
Query: 252 RRMQTAGVTGYPRASIARTLRTIVREEGAVRGLYKGLSMNWVKG-PIAVGISFTTFDLMQ 310
R+ + + TI ++EG + LY+G+S+ V P + G +L +
Sbjct: 132 TRLIMQNILEPSYRGLLHAFSTIYQQEGFL-ALYRGVSLTVVGALPFSAGSLLVYMNLEK 190
Query: 311 I 311
I
Sbjct: 191 I 191
Score = 39.3 bits (90), Expect = 0.005
Identities = 31/101 (30%), Positives = 44/101 (43%), Gaps = 14/101 (13%)
Query: 28 RDHRQVLSSLLPGALAGALAKTAVAPLDRTKIIFQVSSK----------RFS-AKEAFRV 76
RD + + LA A+ +T P + K Q S FS A + FR
Sbjct: 196 RDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGAVDCFRQ 255
Query: 77 LYYTYLNEGFLSLWRGNSATMVRVVPYAAIQFSAHEEYKRI 117
+ +G L LW G +A ++++VPY I FS E KRI
Sbjct: 256 IVKA---QGVLGLWNGLTANLLKIVPYFGIMFSTFEFCKRI 293
>gi|55749577 solute carrier family 25 (mitochondrial carrier;
adenine nucleotide translocator), member 4 [Homo
sapiens]
Length = 298
Score = 120 bits (302), Expect = 1e-27
Identities = 90/283 (31%), Positives = 139/283 (49%), Gaps = 31/283 (10%)
Query: 34 LSSLLPGALAGALAKTAVAPLDRTKIIFQV--SSKRFSAKEAFRVLYYTYLN----EGFL 87
L L G +A A++KTAVAP++R K++ QV +SK+ SA++ ++ + + +GFL
Sbjct: 9 LKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFL 68
Query: 88 SLWRGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGAL-----AG 142
S WRGN A ++R P A+ F+ ++YK++ + G W R FAG L AG
Sbjct: 69 SFWRGNLANVIRYFPTQALNFAFKDKYKQL---FLGGVDRHKQFW-RYFAGNLASGGAAG 124
Query: 143 TTAASLTYPLDLVRARMAV-----TPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGV 197
T+ YPLD R R+A + + + I+I + +GL+ LY GF +V G+
Sbjct: 125 ATSLCFVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGI 184
Query: 198 IPYAGLSFFTYETLKSLHREYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVRRRMQTA 257
I Y F Y+T K + + + F + + SYP D VRRRM
Sbjct: 185 IIYRAAYFGVYDTAKGM---LPDPKNVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQ 241
Query: 258 GVTGYPRASIART-----LRTIVREEGAVRGLYKGLSMNWVKG 295
+G A I T R I ++EGA + +KG N ++G
Sbjct: 242 --SGRKGADIMYTGTVDCWRKIAKDEGA-KAFFKGAWSNVLRG 281
>gi|186928856 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 118 bits (295), Expect = 8e-27
Identities = 79/291 (27%), Positives = 148/291 (50%), Gaps = 31/291 (10%)
Query: 40 GALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYLN--------EGFLSLWR 91
G+++G + + ++P D KI FQ+ +R S + Y+ L EG + W+
Sbjct: 22 GSVSGLVTRALISPFDVIKIRFQLQHERLSRSDP-SAKYHGILQASRQILQEEGPTAFWK 80
Query: 92 GNSATMVRVVPYAAIQFSAHEEYKRIL--GSYYGFRGEALPPWPRLFAGALAGTTAASLT 149
G+ + + Y A+QF + E ++ GS Y R ++ G LA A
Sbjct: 81 GHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSV----HFVCGGLAACMATLTV 136
Query: 150 YPLDLVRARMAVTPK-EMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTY 208
+P+D++R R A + ++Y+ + H + R EG + Y G PT++ + PYAGL F Y
Sbjct: 137 HPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCY 196
Query: 209 ETLKSLHR---EYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVRRRMQTAGVTGYPRA 265
+LK L++ G++ + ++ G+ AG+I ++ +YPLD+ ++R+Q G + RA
Sbjct: 197 SSLKHLYKWAIPAEGKKNE-NLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFE-HARA 254
Query: 266 SIARTLR---------TIVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFD 307
+ + R ++++EGA+ G +KGLS + +K ++ G F +++
Sbjct: 255 AFGQVRRYKGLMDCAKQVLQKEGAL-GFFKGLSPSLLKAALSTGFMFFSYE 304
Score = 52.8 bits (125), Expect = 4e-07
Identities = 51/195 (26%), Positives = 81/195 (41%), Gaps = 28/195 (14%)
Query: 137 AGALAGTTAASLTYPLDLVRARMAV--------TPKEMYSNIFHVFIRISREEGLKTLYH 188
AG+++G +L P D+++ R + P Y I +I +EEG +
Sbjct: 21 AGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFWK 80
Query: 189 GFMPTVLGVIPYAGLSFFTYETLKSL-HR--EYSGRRQPYPFERMIFGACAGLIGQSASY 245
G +P + I Y + F ++E L L HR Y R F + G A + +
Sbjct: 81 GHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHF---VCGGLAACMATLTVH 137
Query: 246 PLDVVRRRMQTAGVTGYPRASIARTLR----TIVREEGAVRGLYKGLSMNWVKGPIAVGI 301
P+DV+R R G + TLR T+ R EG + YKGL+ + G+
Sbjct: 138 PVDVLRTRFAAQG-----EPKVYNTLRHAVGTMYRSEGP-QVFYKGLAPTLIAIFPYAGL 191
Query: 302 SFTTFDLMQIMLRHL 316
F+ + L+HL
Sbjct: 192 QFSCYS----SLKHL 202
Score = 30.0 bits (66), Expect = 2.8
Identities = 24/88 (27%), Positives = 38/88 (43%), Gaps = 9/88 (10%)
Query: 34 LSSLLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYL---------NE 84
L +LL G+ AG ++KT PLD K QV + +V Y L E
Sbjct: 217 LQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKE 276
Query: 85 GFLSLWRGNSATMVRVVPYAAIQFSAHE 112
G L ++G S ++++ F ++E
Sbjct: 277 GALGFFKGLSPSLLKAALSTGFMFFSYE 304
>gi|186928860 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 118 bits (295), Expect = 8e-27
Identities = 79/291 (27%), Positives = 148/291 (50%), Gaps = 31/291 (10%)
Query: 40 GALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYLN--------EGFLSLWR 91
G+++G + + ++P D KI FQ+ +R S + Y+ L EG + W+
Sbjct: 22 GSVSGLVTRALISPFDVIKIRFQLQHERLSRSDP-SAKYHGILQASRQILQEEGPTAFWK 80
Query: 92 GNSATMVRVVPYAAIQFSAHEEYKRIL--GSYYGFRGEALPPWPRLFAGALAGTTAASLT 149
G+ + + Y A+QF + E ++ GS Y R ++ G LA A
Sbjct: 81 GHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSV----HFVCGGLAACMATLTV 136
Query: 150 YPLDLVRARMAVTPK-EMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTY 208
+P+D++R R A + ++Y+ + H + R EG + Y G PT++ + PYAGL F Y
Sbjct: 137 HPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCY 196
Query: 209 ETLKSLHR---EYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVRRRMQTAGVTGYPRA 265
+LK L++ G++ + ++ G+ AG+I ++ +YPLD+ ++R+Q G + RA
Sbjct: 197 SSLKHLYKWAIPAEGKKNE-NLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFE-HARA 254
Query: 266 SIARTLR---------TIVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFD 307
+ + R ++++EGA+ G +KGLS + +K ++ G F +++
Sbjct: 255 AFGQVRRYKGLMDCAKQVLQKEGAL-GFFKGLSPSLLKAALSTGFMFFSYE 304
Score = 52.8 bits (125), Expect = 4e-07
Identities = 51/195 (26%), Positives = 81/195 (41%), Gaps = 28/195 (14%)
Query: 137 AGALAGTTAASLTYPLDLVRARMAV--------TPKEMYSNIFHVFIRISREEGLKTLYH 188
AG+++G +L P D+++ R + P Y I +I +EEG +
Sbjct: 21 AGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFWK 80
Query: 189 GFMPTVLGVIPYAGLSFFTYETLKSL-HR--EYSGRRQPYPFERMIFGACAGLIGQSASY 245
G +P + I Y + F ++E L L HR Y R F + G A + +
Sbjct: 81 GHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHF---VCGGLAACMATLTVH 137
Query: 246 PLDVVRRRMQTAGVTGYPRASIARTLR----TIVREEGAVRGLYKGLSMNWVKGPIAVGI 301
P+DV+R R G + TLR T+ R EG + YKGL+ + G+
Sbjct: 138 PVDVLRTRFAAQG-----EPKVYNTLRHAVGTMYRSEGP-QVFYKGLAPTLIAIFPYAGL 191
Query: 302 SFTTFDLMQIMLRHL 316
F+ + L+HL
Sbjct: 192 QFSCYS----SLKHL 202
Score = 30.0 bits (66), Expect = 2.8
Identities = 24/88 (27%), Positives = 38/88 (43%), Gaps = 9/88 (10%)
Query: 34 LSSLLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYL---------NE 84
L +LL G+ AG ++KT PLD K QV + +V Y L E
Sbjct: 217 LQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKE 276
Query: 85 GFLSLWRGNSATMVRVVPYAAIQFSAHE 112
G L ++G S ++++ F ++E
Sbjct: 277 GALGFFKGLSPSLLKAALSTGFMFFSYE 304
>gi|186928858 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 118 bits (295), Expect = 8e-27
Identities = 79/291 (27%), Positives = 148/291 (50%), Gaps = 31/291 (10%)
Query: 40 GALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYLN--------EGFLSLWR 91
G+++G + + ++P D KI FQ+ +R S + Y+ L EG + W+
Sbjct: 22 GSVSGLVTRALISPFDVIKIRFQLQHERLSRSDP-SAKYHGILQASRQILQEEGPTAFWK 80
Query: 92 GNSATMVRVVPYAAIQFSAHEEYKRIL--GSYYGFRGEALPPWPRLFAGALAGTTAASLT 149
G+ + + Y A+QF + E ++ GS Y R ++ G LA A
Sbjct: 81 GHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSV----HFVCGGLAACMATLTV 136
Query: 150 YPLDLVRARMAVTPK-EMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTY 208
+P+D++R R A + ++Y+ + H + R EG + Y G PT++ + PYAGL F Y
Sbjct: 137 HPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCY 196
Query: 209 ETLKSLHR---EYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVRRRMQTAGVTGYPRA 265
+LK L++ G++ + ++ G+ AG+I ++ +YPLD+ ++R+Q G + RA
Sbjct: 197 SSLKHLYKWAIPAEGKKNE-NLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFE-HARA 254
Query: 266 SIARTLR---------TIVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFD 307
+ + R ++++EGA+ G +KGLS + +K ++ G F +++
Sbjct: 255 AFGQVRRYKGLMDCAKQVLQKEGAL-GFFKGLSPSLLKAALSTGFMFFSYE 304
Score = 52.8 bits (125), Expect = 4e-07
Identities = 51/195 (26%), Positives = 81/195 (41%), Gaps = 28/195 (14%)
Query: 137 AGALAGTTAASLTYPLDLVRARMAV--------TPKEMYSNIFHVFIRISREEGLKTLYH 188
AG+++G +L P D+++ R + P Y I +I +EEG +
Sbjct: 21 AGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFWK 80
Query: 189 GFMPTVLGVIPYAGLSFFTYETLKSL-HR--EYSGRRQPYPFERMIFGACAGLIGQSASY 245
G +P + I Y + F ++E L L HR Y R F + G A + +
Sbjct: 81 GHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHF---VCGGLAACMATLTVH 137
Query: 246 PLDVVRRRMQTAGVTGYPRASIARTLR----TIVREEGAVRGLYKGLSMNWVKGPIAVGI 301
P+DV+R R G + TLR T+ R EG + YKGL+ + G+
Sbjct: 138 PVDVLRTRFAAQG-----EPKVYNTLRHAVGTMYRSEGP-QVFYKGLAPTLIAIFPYAGL 191
Query: 302 SFTTFDLMQIMLRHL 316
F+ + L+HL
Sbjct: 192 QFSCYS----SLKHL 202
Score = 30.0 bits (66), Expect = 2.8
Identities = 24/88 (27%), Positives = 38/88 (43%), Gaps = 9/88 (10%)
Query: 34 LSSLLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYL---------NE 84
L +LL G+ AG ++KT PLD K QV + +V Y L E
Sbjct: 217 LQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKE 276
Query: 85 GFLSLWRGNSATMVRVVPYAAIQFSAHE 112
G L ++G S ++++ F ++E
Sbjct: 277 GALGFFKGLSPSLLKAALSTGFMFFSYE 304
>gi|13775208 solute carrier family 25 (mitochondrial carrier;
adenine nucleotide translocator), member 31 [Homo
sapiens]
Length = 315
Score = 117 bits (294), Expect = 1e-26
Identities = 84/277 (30%), Positives = 142/277 (51%), Gaps = 27/277 (9%)
Query: 37 LLPGALAGALAKTAVAPLDRTKIIFQV--SSKRFSAKEAFRVLYYTYLN----EGFLSLW 90
LL G +A A++KTAVAP++R K++ QV SSK+ S + ++ + + +GF S W
Sbjct: 24 LLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFSFW 83
Query: 91 RGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPW--PRLFAGALAGTTAASL 148
RGN A ++R P A+ F+ ++YK++ S + + W L +G AG T+ +
Sbjct: 84 RGNLANVIRYFPTQALNFAFKDKYKQLFMSGVN-KEKQFWRWFLANLASGGAAGATSLCV 142
Query: 149 TYPLDLVRARMAVT----PKE-MYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGL 203
YPLD R R+ V P+E + + ++I++ +G+ LY GF +V G+I Y
Sbjct: 143 VYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYRAS 202
Query: 204 SFFTYETLKSLHREYSGRRQPYP---FERMIFGACAGLIGQSASYPLDVVRRRMQTAGVT 260
F Y+T+K L + ++ P+ F + C+G++ SYP D VRRRM +
Sbjct: 203 YFGAYDTVKGLLPK--PKKTPFLVSFFIAQVVTTCSGIL----SYPFDTVRRRMMMQ--S 254
Query: 261 GYPRASIARTLRTIVR--EEGAVRGLYKGLSMNWVKG 295
G + TL V+ + + ++G N ++G
Sbjct: 255 GEAKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLRG 291
Score = 57.0 bits (136), Expect = 2e-08
Identities = 52/210 (24%), Positives = 88/210 (41%), Gaps = 14/210 (6%)
Query: 20 LSSSVSSKRDHRQVLSSLLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYY 79
+S K+ R L++L G AGA + V PLD + V + + F+ L
Sbjct: 112 MSGVNKEKQFWRWFLANLASGGAAGATSLCVVYPLDFARTRLGVDIGKGPEERQFKGLGD 171
Query: 80 TYL----NEGFLSLWRGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRL 135
+ ++G L++G ++ ++ Y A F A++ K +L + + P
Sbjct: 172 CIMKIAKSDGIAGLYQGFGVSVQGIIVYRASYFGAYDTVKGLLP-----KPKKTPFLVSF 226
Query: 136 FAGALAGTTAASLTYPLDLVRARMAV---TPKEMYSNIFHVFIRISREEGLKTLYHGFMP 192
F + T + L+YP D VR RM + K Y F++I + EG+ + + G
Sbjct: 227 FIAQVVTTCSGILSYPFDTVRRRMMMQSGEAKRQYKGTLDCFVKIYQHEGISSFFRGAFS 286
Query: 193 TVLGVIPYAGLSFFTYETLKS-LHREYSGR 221
VL A L Y+ +K H + GR
Sbjct: 287 NVLRGTGGA-LVLVLYDKIKEFFHIDIGGR 315
>gi|156071462 solute carrier family 25, member A6 [Homo sapiens]
Length = 298
Score = 114 bits (285), Expect = 1e-25
Identities = 87/280 (31%), Positives = 138/280 (49%), Gaps = 33/280 (11%)
Query: 38 LPGALAGALAKTAVAPLDRTKIIFQV--SSKRFSAKEAFRVLYYTYLN----EGFLSLWR 91
L G +A A++KTAVAP++R K++ QV +SK+ +A + ++ + + +G LS WR
Sbjct: 13 LAGGIAAAISKTAVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVRIPKEQGVLSFWR 72
Query: 92 GNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGAL-----AGTTAA 146
GN A ++R P A+ F+ ++YK+I + G + W R FAG L AG T+
Sbjct: 73 GNLANVIRYFPTQALNFAFKDKYKQI---FLGGVDKHTQFW-RYFAGNLASGGAAGATSL 128
Query: 147 SLTYPLDLVRARMAV------TPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPY 200
YPLD R R+A T +E + + ++I++ +G++ LY GF +V G+I Y
Sbjct: 129 CFVYPLDFARTRLAADVGKSGTERE-FRGLGDCLVKITKSDGIRGLYQGFSVSVQGIIIY 187
Query: 201 AGLSFFTYETLKSLHREYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVRRRMQTAGVT 260
F Y+T K + + + + + SYP D VRRRM +
Sbjct: 188 RAAYFGVYDTAKGM---LPDPKNTHIVVSWMIAQTVTAVAGVVSYPFDTVRRRMMMQ--S 242
Query: 261 GYPRASIART-----LRTIVREEGAVRGLYKGLSMNWVKG 295
G A I T R I R+EG + +KG N ++G
Sbjct: 243 GRKGADIMYTGTVDCWRKIFRDEGG-KAFFKGAWSNVLRG 281
>gi|156071459 solute carrier family 25, member 5 [Homo sapiens]
Length = 298
Score = 111 bits (278), Expect = 7e-25
Identities = 84/276 (30%), Positives = 133/276 (48%), Gaps = 25/276 (9%)
Query: 38 LPGALAGALAKTAVAPLDRTKIIFQV--SSKRFSAKEAFRVLYYTYLN----EGFLSLWR 91
L G +A A++KTAVAP++R K++ QV +SK+ +A + ++ + + +G LS WR
Sbjct: 13 LAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSFWR 72
Query: 92 GNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPW----PRLFAGALAGTTAAS 147
GN A ++R P A+ F+ ++YK+I + G + W L +G AG T+
Sbjct: 73 GNLANVIRYFPTQALNFAFKDKYKQI---FLGGVDKRTQFWLYFAGNLASGGAAGATSLC 129
Query: 148 LTYPLDLVRARMAVT-----PKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAG 202
YPLD R R+A + + + ++I + +G+K LY GF +V G+I Y
Sbjct: 130 FVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRA 189
Query: 203 LSFFTYETLKSLHREYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVRRRMQTAGVTGY 262
F Y+T K + + + MI + G + SYP D VRRRM
Sbjct: 190 AYFGIYDTAKGMLPD--PKNTHIVISWMIAQTVTAVAGLT-SYPFDTVRRRMMMQSGRKG 246
Query: 263 PRASIARTL---RTIVREEGAVRGLYKGLSMNWVKG 295
TL R I R+EG + +KG N ++G
Sbjct: 247 TDIMYTGTLDCWRKIARDEGG-KAFFKGAWSNVLRG 281
Score = 45.1 bits (105), Expect = 9e-05
Identities = 46/176 (26%), Positives = 72/176 (40%), Gaps = 28/176 (15%)
Query: 36 SLLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFR----VLYYTYLNEGFLSLWR 91
+L G AGA + V PLD + + A+ FR L Y ++G L++
Sbjct: 116 NLASGGAAGATSLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQ 175
Query: 92 GNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPR------LFAGALAGTTA 145
G + ++ ++ Y A F ++ K +L P P+ + A T
Sbjct: 176 GFNVSVQGIIIYRAAYFGIYDTAKGML------------PDPKNTHIVISWMIAQTVTAV 223
Query: 146 ASLT-YPLDLVRARMAVTPKE-----MYSNIFHVFIRISREEGLKTLYHGFMPTVL 195
A LT YP D VR RM + MY+ + +I+R+EG K + G VL
Sbjct: 224 AGLTSYPFDTVRRRMMMQSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVL 279
>gi|46094065 mitochondrial carrier family protein [Homo sapiens]
Length = 338
Score = 92.0 bits (227), Expect = 6e-19
Identities = 70/233 (30%), Positives = 110/233 (47%), Gaps = 15/233 (6%)
Query: 83 NEGFLSLWRGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALAG 142
NEG SLW G T+V VP I F+ +++ +L S G +P + AG +A
Sbjct: 97 NEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGENETCIP----IVAGIVAR 152
Query: 143 TTAASLTYPLDLVRARMAVTPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAG 202
A ++ PL+L+R +M + K Y + + E+G +L+ G+ PTVL +P++
Sbjct: 153 FGAVTVISPLELIRTKMQ-SKKFSYVELHRFVSKKVSEDGWISLWRGWAPTVLRDVPFSA 211
Query: 203 LSFFTYETLKSLHREYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVRRRMQTAGVTGY 262
+ ++ YE LK E SG +P GA +G A+ P DVV+ + QT T Y
Sbjct: 212 MYWYNYEILKKWLCEKSGLYEPTFMINFTSGALSGSFAAVATLPFDVVKTQKQTQLWT-Y 270
Query: 263 PRASIARTL--------RTIVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFD 307
I+ L + IV + G GL+ GL +K A I +T++
Sbjct: 271 ESHKISMPLHMSTWIIMKNIVAKNG-FSGLFSGLIPRLIKIAPACAIMISTYE 322
Score = 76.3 bits (186), Expect = 3e-14
Identities = 58/217 (26%), Positives = 104/217 (47%), Gaps = 17/217 (7%)
Query: 20 LSSSVSSKRDHRQVLSSLLPGALAGALAKTAVAPLD--RTKIIFQVSSKRFSAKEAFRVL 77
LS+ + SK + ++ G +A A T ++PL+ RTK+ SK+FS E R +
Sbjct: 128 LSALLRSKLGENETCIPIVAGIVARFGAVTVISPLELIRTKM----QSKKFSYVELHRFV 183
Query: 78 YYTYLNEGFLSLWRGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFA 137
+G++SLWRG + T++R VP++A+ + +E K+ L G +
Sbjct: 184 SKKVSEDGWISLWRGWAPTVLRDVPFSAMYWYNYEILKKWLCEKSGLYEPTF--MINFTS 241
Query: 138 GALAGTTAASLTYPLDLVRARMAV---------TPKEMYSNIFHVFIRISREEGLKTLYH 188
GAL+G+ AA T P D+V+ + ++ + + + I + G L+
Sbjct: 242 GALSGSFAAVATLPFDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFS 301
Query: 189 GFMPTVLGVIPYAGLSFFTYETLKSLHREYSGRRQPY 225
G +P ++ + P + TYE K+ ++ + RRQ Y
Sbjct: 302 GLIPRLIKIAPACAIMISTYEFGKAFFQKQNVRRQQY 338
Score = 42.4 bits (98), Expect = 6e-04
Identities = 24/90 (26%), Positives = 44/90 (48%), Gaps = 2/90 (2%)
Query: 167 YSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTYETLKSLHREYSGRRQPYP 226
+ F +I R EG+K+L+ G PT++ +P + F Y+ L +L R G +
Sbjct: 84 FQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGENE--T 141
Query: 227 FERMIFGACAGLIGQSASYPLDVVRRRMQT 256
++ G A + PL+++R +MQ+
Sbjct: 142 CIPIVAGIVARFGAVTVISPLELIRTKMQS 171
>gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo
sapiens]
Length = 675
Score = 89.7 bits (221), Expect = 3e-18
Identities = 76/278 (27%), Positives = 130/278 (46%), Gaps = 15/278 (5%)
Query: 40 GALAGALAKTAVAPLD--RTKIIFQVSSKRFSA----KEAFRVLYYTYLNEGFLSLWRGN 93
G++AGA+ TAV P+D +T++ Q S+ F K +F EGF L+RG
Sbjct: 335 GSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGL 394
Query: 94 SATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALAGTTAASLTYPLD 153
++ V P AI+ + ++ + + + ++P + AG AG + T PL+
Sbjct: 395 LPQLLGVAPEKAIKLTVND----FVRDKFMHKDGSVPLAAEILAGGCAGGSQVIFTNPLE 450
Query: 154 LVRARMAVTPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTYETLKS 213
+V+ R+ V E+ + + + R+ G +Y G L IP++ + F Y +K+
Sbjct: 451 IVKIRLQVAG-EITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKA 509
Query: 214 LHREYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVRRRMQTAGVTGYPRAS-IARTLR 272
G Q P ++ GA AG+ S P DV++ R+Q A G S + R
Sbjct: 510 SFANEDG--QVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFR 567
Query: 273 TIVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFDLMQ 310
I+REEG + L+KG + G++ T++L+Q
Sbjct: 568 KILREEGP-KALWKGAGARVFRSSPQFGVTLLTYELLQ 604
Score = 80.1 bits (196), Expect = 2e-15
Identities = 60/186 (32%), Positives = 88/186 (47%), Gaps = 19/186 (10%)
Query: 35 SSLLPGALAGALAKTAVAPLDRTKIIFQVSSK-----RFSAKEAFRVLYYTYLNEGFLSL 89
+ +L G AG PL+ KI QV+ + R SA R L GF +
Sbjct: 430 AEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDL-------GFFGI 482
Query: 90 WRGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALAGTTAASLT 149
++G A +R +P++AI F Y + S+ G+ + P L AGA+AG AASL
Sbjct: 483 YKGAKACFLRDIPFSAIYFPC---YAHVKASFANEDGQ-VSPGSLLLAGAIAGMPAASLV 538
Query: 150 YPLDLVRARMAVTPKE---MYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFF 206
P D+++ R+ V + YS + F +I REEG K L+ G V P G++
Sbjct: 539 TPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLL 598
Query: 207 TYETLK 212
TYE L+
Sbjct: 599 TYELLQ 604
Score = 72.4 bits (176), Expect = 5e-13
Identities = 55/164 (33%), Positives = 84/164 (51%), Gaps = 19/164 (11%)
Query: 134 RLFAGALAGTTAASLTYPLDLVRARM-------AVTPKEMYSNIFHVFIRISREEGLKTL 186
R G++AG A+ YP+DLV+ RM + + MY N F F ++ R EG L
Sbjct: 331 RFGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGL 390
Query: 187 YHGFMPTVLGVIPYAGLSFFTYETL--KSLHREYSGRRQPYPFERMIFGACAGLIGQSAS 244
Y G +P +LGV P + + + K +H++ S P E ++ G CAG +
Sbjct: 391 YRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGS---VPLAAE-ILAGGCAGGSQVIFT 446
Query: 245 YPLDVVRRRMQTAG-VTGYPRASIARTLRTIVREEGAVRGLYKG 287
PL++V+ R+Q AG +T PR S ++VR+ G G+YKG
Sbjct: 447 NPLEIVKIRLQVAGEITTGPRVSAL----SVVRDLGFF-GIYKG 485
Score = 33.5 bits (75), Expect = 0.26
Identities = 26/87 (29%), Positives = 39/87 (44%), Gaps = 8/87 (9%)
Query: 35 SSLLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAK-----EAFRVLYYTYLNEGFLSL 89
S LL GA+AG A + V P D K QV+++ + FR + EG +L
Sbjct: 522 SLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILR---EEGPKAL 578
Query: 90 WRGNSATMVRVVPYAAIQFSAHEEYKR 116
W+G A + R P + +E +R
Sbjct: 579 WKGAGARVFRSSPQFGVTLLTYELLQR 605
>gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo
sapiens]
Length = 676
Score = 89.7 bits (221), Expect = 3e-18
Identities = 76/278 (27%), Positives = 130/278 (46%), Gaps = 15/278 (5%)
Query: 40 GALAGALAKTAVAPLD--RTKIIFQVSSKRFSA----KEAFRVLYYTYLNEGFLSLWRGN 93
G++AGA+ TAV P+D +T++ Q S+ F K +F EGF L+RG
Sbjct: 336 GSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGL 395
Query: 94 SATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALAGTTAASLTYPLD 153
++ V P AI+ + ++ + + + ++P + AG AG + T PL+
Sbjct: 396 LPQLLGVAPEKAIKLTVND----FVRDKFMHKDGSVPLAAEILAGGCAGGSQVIFTNPLE 451
Query: 154 LVRARMAVTPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTYETLKS 213
+V+ R+ V E+ + + + R+ G +Y G L IP++ + F Y +K+
Sbjct: 452 IVKIRLQVAG-EITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKA 510
Query: 214 LHREYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVRRRMQTAGVTGYPRAS-IARTLR 272
G Q P ++ GA AG+ S P DV++ R+Q A G S + R
Sbjct: 511 SFANEDG--QVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFR 568
Query: 273 TIVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFDLMQ 310
I+REEG + L+KG + G++ T++L+Q
Sbjct: 569 KILREEGP-KALWKGAGARVFRSSPQFGVTLLTYELLQ 605
Score = 80.1 bits (196), Expect = 2e-15
Identities = 60/186 (32%), Positives = 88/186 (47%), Gaps = 19/186 (10%)
Query: 35 SSLLPGALAGALAKTAVAPLDRTKIIFQVSSK-----RFSAKEAFRVLYYTYLNEGFLSL 89
+ +L G AG PL+ KI QV+ + R SA R L GF +
Sbjct: 431 AEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDL-------GFFGI 483
Query: 90 WRGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALAGTTAASLT 149
++G A +R +P++AI F Y + S+ G+ + P L AGA+AG AASL
Sbjct: 484 YKGAKACFLRDIPFSAIYFPC---YAHVKASFANEDGQ-VSPGSLLLAGAIAGMPAASLV 539
Query: 150 YPLDLVRARMAVTPKE---MYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFF 206
P D+++ R+ V + YS + F +I REEG K L+ G V P G++
Sbjct: 540 TPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLL 599
Query: 207 TYETLK 212
TYE L+
Sbjct: 600 TYELLQ 605
Score = 72.4 bits (176), Expect = 5e-13
Identities = 55/164 (33%), Positives = 84/164 (51%), Gaps = 19/164 (11%)
Query: 134 RLFAGALAGTTAASLTYPLDLVRARM-------AVTPKEMYSNIFHVFIRISREEGLKTL 186
R G++AG A+ YP+DLV+ RM + + MY N F F ++ R EG L
Sbjct: 332 RFGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGL 391
Query: 187 YHGFMPTVLGVIPYAGLSFFTYETL--KSLHREYSGRRQPYPFERMIFGACAGLIGQSAS 244
Y G +P +LGV P + + + K +H++ S P E ++ G CAG +
Sbjct: 392 YRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGS---VPLAAE-ILAGGCAGGSQVIFT 447
Query: 245 YPLDVVRRRMQTAG-VTGYPRASIARTLRTIVREEGAVRGLYKG 287
PL++V+ R+Q AG +T PR S ++VR+ G G+YKG
Sbjct: 448 NPLEIVKIRLQVAGEITTGPRVSAL----SVVRDLGFF-GIYKG 486
Score = 33.5 bits (75), Expect = 0.26
Identities = 26/87 (29%), Positives = 39/87 (44%), Gaps = 8/87 (9%)
Query: 35 SSLLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAK-----EAFRVLYYTYLNEGFLSL 89
S LL GA+AG A + V P D K QV+++ + FR + EG +L
Sbjct: 523 SLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILR---EEGPKAL 579
Query: 90 WRGNSATMVRVVPYAAIQFSAHEEYKR 116
W+G A + R P + +E +R
Sbjct: 580 WKGAGARVFRSSPQFGVTLLTYELLQR 606
>gi|58197562 solute carrier family 25, member 30 [Homo sapiens]
Length = 291
Score = 89.4 bits (220), Expect = 4e-18
Identities = 60/185 (32%), Positives = 91/185 (49%), Gaps = 13/185 (7%)
Query: 132 WPRLFAGALAGTTAASLTYPLDLVRARMAVTP-------KEM-YSNIFHVFIRISREEGL 183
W G LA TA T+P+DL + R+ + KE+ Y + H +RI REEGL
Sbjct: 6 WKPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGL 65
Query: 184 KTLYHGFMPTVLGVIPYAGLSFFTYETLKSLHREYSGRRQPYPFERMIFGACAGLIGQSA 243
K LY G P +L Y + TY++LK L E + P +I G +G+I +
Sbjct: 66 KALYSGIAPAMLRQASYGTIKIGTYQSLKRLFIE-RPEDETLPI-NVICGILSGVISSTI 123
Query: 244 SYPLDVVRRRMQTAGVTGYPRASIARTLRTIVREEGAVRGLYKGLSMNWVKGPIAVGISF 303
+ P DV++ RMQ T + + I ++EG RGL+KG+S+ + I VG+
Sbjct: 124 ANPTDVLKIRMQAQSNT--IQGGMIGNFMNIYQQEG-TRGLWKGVSLTAQRAAIVVGVEL 180
Query: 304 TTFDL 308
+D+
Sbjct: 181 PVYDI 185
Score = 80.1 bits (196), Expect = 2e-15
Identities = 76/285 (26%), Positives = 122/285 (42%), Gaps = 23/285 (8%)
Query: 40 GALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYL---------NEGFLSLW 90
G LA A+ P+D TK Q+ + AK F+ + Y + EG +L+
Sbjct: 12 GGLASITAECGTFPIDLTKTRLQIQGQTNDAK--FKEIRYRGMLHALVRIGREEGLKALY 69
Query: 91 RGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALAGTTAASLTY 150
G + M+R Y I+ ++ KR+ E LP + G L+G ++++
Sbjct: 70 SGIAPAMLRQASYGTIKIGTYQSLKRLFIERP--EDETLPI--NVICGILSGVISSTIAN 125
Query: 151 PLDLVRARMAVTPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTYET 210
P D+++ RM + + F+ I ++EG + L+ G T G+ Y+
Sbjct: 126 PTDVLKIRMQAQSNTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDI 185
Query: 211 LKSLHREYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVRRRMQTAGVTGYPRAS-IAR 269
K H SG + + GL G AS P+DVVR RM V R S
Sbjct: 186 TKK-HLILSGLMGDTVYTHFLSSFTCGLAGALASNPVDVVRTRMMNQRVLRDGRCSGYTG 244
Query: 270 TLRTIV---REEGAVRGLYKGLSMNWVK-GPIAVGISFTTFDLMQ 310
TL ++ + EG LYKG NW++ GP + I F T++ ++
Sbjct: 245 TLDCLLQTWKNEGFF-ALYKGFWPNWLRLGPWNI-IFFVTYEQLK 287
Score = 58.5 bits (140), Expect = 7e-09
Identities = 48/186 (25%), Positives = 78/186 (41%), Gaps = 12/186 (6%)
Query: 36 SLLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYLNEGFLSLWRGNSA 95
+++ G L+G ++ T P D KI Q S + Y EG LW+G S
Sbjct: 109 NVICGILSGVISSTIANPTDVLKIRMQAQSNTIQGGMIGNFMNI-YQQEGTRGLWKGVSL 167
Query: 96 TMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALAGTTAASLTYPLDLV 155
T R ++ ++ K+ L G G+ + + + G A + P+D+V
Sbjct: 168 TAQRAAIVVGVELPVYDITKKHL-ILSGLMGDTV--YTHFLSSFTCGLAGALASNPVDVV 224
Query: 156 RARMAVTPKEM-------YSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTY 208
R RM + + + Y+ ++ + EG LY GF P L + P+ + F TY
Sbjct: 225 RTRM-MNQRVLRDGRCSGYTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTY 283
Query: 209 ETLKSL 214
E LK L
Sbjct: 284 EQLKKL 289
>gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens]
Length = 301
Score = 89.4 bits (220), Expect = 4e-18
Identities = 73/285 (25%), Positives = 126/285 (44%), Gaps = 16/285 (5%)
Query: 34 LSSLLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKE-----AFRVLYYTYLNEGFLS 88
L +LL G G PLD K+ Q + F T EG
Sbjct: 11 LKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREGITG 70
Query: 89 LWRGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFA-GALAGTTAAS 147
L+RG +A ++ V P A+ F K++ + E + +P+LFA G L+G
Sbjct: 71 LYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQKH----PEDVLSYPQLFAAGMLSGVFTTG 126
Query: 148 LTYPLDLVRARMAV---TPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLS 204
+ P + ++ + + + + Y+ ++ +E G++ +Y G + T++ +P +G+
Sbjct: 127 IMTPGERIKCLLQIQASSGESKYTGTLDCAKKLYQEFGIRGIYKGTVLTLMRDVPASGMY 186
Query: 205 FFTYETLKSLHREYSGRRQPYPFER-MIFGACAGLIGQSASYPLDVVRRRMQTAGVTGYP 263
F TYE LK++ R R ++ G AG+ + + P DV++ R QTA YP
Sbjct: 187 FMTYEWLKNIFTPEGKRVSELSAPRILVAGGIAGIFNWAVAIPPDVLKSRFQTAPPGKYP 246
Query: 264 RASIARTLRTIVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFDL 308
LR ++R+EG V LYKG + ++ A F F++
Sbjct: 247 N-GFRDVLRELIRDEG-VTSLYKGFNAVMIRAFPANAACFLGFEV 289
Score = 66.6 bits (161), Expect = 3e-11
Identities = 45/188 (23%), Positives = 81/188 (43%), Gaps = 7/188 (3%)
Query: 129 LPPWPRLFAGALAGTTAASLTYPLDLVRARMAVTPKE------MYSNIFHVFIRISREEG 182
+ P L AG G + +PLD V+ R+ P MYS F F + EG
Sbjct: 8 ISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREG 67
Query: 183 LKTLYHGFMPTVLGVIPYAGLSFFTYETLKSLHREYSGRRQPYPFERMIFGACAGLIGQS 242
+ LY G ++GV P + FF + K L +++ YP + G +G+
Sbjct: 68 ITGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQKHPEDVLSYP-QLFAAGMLSGVFTTG 126
Query: 243 ASYPLDVVRRRMQTAGVTGYPRASIARTLRTIVREEGAVRGLYKGLSMNWVKGPIAVGIS 302
P + ++ +Q +G + + + +E +RG+YKG + ++ A G+
Sbjct: 127 IMTPGERIKCLLQIQASSGESKYTGTLDCAKKLYQEFGIRGIYKGTVLTLMRDVPASGMY 186
Query: 303 FTTFDLMQ 310
F T++ ++
Sbjct: 187 FMTYEWLK 194
Score = 30.8 bits (68), Expect = 1.7
Identities = 24/82 (29%), Positives = 33/82 (40%)
Query: 37 LLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYLNEGFLSLWRGNSAT 96
L+ G +AG P D K FQ + VL +EG SL++G +A
Sbjct: 213 LVAGGIAGIFNWAVAIPPDVLKSRFQTAPPGKYPNGFRDVLRELIRDEGVTSLYKGFNAV 272
Query: 97 MVRVVPYAAIQFSAHEEYKRIL 118
M+R P A F E + L
Sbjct: 273 MIRAFPANAACFLGFEVAMKFL 294
>gi|21361103 solute carrier family 25, member 12 [Homo sapiens]
Length = 678
Score = 84.7 bits (208), Expect = 1e-16
Identities = 75/280 (26%), Positives = 127/280 (45%), Gaps = 19/280 (6%)
Query: 40 GALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYLN--------EGFLSLWR 91
G++AGA+ TAV P+D K Q ++R S ++Y + EGF L+R
Sbjct: 333 GSVAGAVGATAVYPIDLVKTRMQ--NQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYR 390
Query: 92 GNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALAGTTAASLTYP 151
G ++ V P AI+ + ++ + + R ++P + AG AG + T P
Sbjct: 391 GLIPQLIGVAPEKAIKLTVND----FVRDKFTRRDGSVPLPAEVLAGGCAGGSQVIFTNP 446
Query: 152 LDLVRARMAVTPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTYETL 211
L++V+ R+ V E+ + + + R+ G+ LY G L IP++ + F Y
Sbjct: 447 LEIVKIRLQVAG-EITTGPRVSALNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYAHC 505
Query: 212 KSLHREYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVRRRMQTAGVTGYPRAS-IART 270
K L + +G + GA AG+ S P DV++ R+Q A G S +
Sbjct: 506 KLLLADENGHVGG--LNLLAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVIDC 563
Query: 271 LRTIVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFDLMQ 310
R I+REEG +KG + + G++ T++L+Q
Sbjct: 564 FRKILREEGP-SAFWKGTAARVFRSSPQFGVTLVTYELLQ 602
Score = 79.7 bits (195), Expect = 3e-15
Identities = 60/191 (31%), Positives = 92/191 (48%), Gaps = 21/191 (10%)
Query: 134 RLFAGALAGTTAASLTYPLDLVRARM-------AVTPKEMYSNIFHVFIRISREEGLKTL 186
R G++AG A+ YP+DLV+ RM +V + MY N F F ++ R EG L
Sbjct: 329 RFTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGL 388
Query: 187 YHGFMPTVLGVIPYAGLSFFTYETLKSLHREYSGRRQ---PYPFERMIFGACAGLIGQSA 243
Y G +P ++GV P + T+ R+ RR P P E ++ G CAG
Sbjct: 389 YRGLIPQLIGVAPEKAIKL----TVNDFVRDKFTRRDGSVPLPAE-VLAGGCAGGSQVIF 443
Query: 244 SYPLDVVRRRMQTAG-VTGYPRASIARTLRTIVREEGAVRGLYKGLSMNWVKGPIAVGIS 302
+ PL++V+ R+Q AG +T PR S LR + + GLYKG +++ I
Sbjct: 444 TNPLEIVKIRLQVAGEITTGPRVSALNVLRDL-----GIFGLYKGAKACFLRDIPFSAIY 498
Query: 303 FTTFDLMQIML 313
F + +++L
Sbjct: 499 FPVYAHCKLLL 509
Score = 74.7 bits (182), Expect = 1e-13
Identities = 58/186 (31%), Positives = 83/186 (44%), Gaps = 19/186 (10%)
Query: 35 SSLLPGALAGALAKTAVAPLDRTKIIFQVSSK-----RFSAKEAFRVLYYTYLNEGFLSL 89
+ +L G AG PL+ KI QV+ + R SA R L G L
Sbjct: 428 AEVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDL-------GIFGL 480
Query: 90 WRGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALAGTTAASLT 149
++G A +R +P++AI F + K +L G G L AGA+AG AASL
Sbjct: 481 YKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGL----NLLAAGAMAGVPAASLV 536
Query: 150 YPLDLVRARMAVTPK---EMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFF 206
P D+++ R+ V + YS + F +I REEG + G V P G++
Sbjct: 537 TPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLV 596
Query: 207 TYETLK 212
TYE L+
Sbjct: 597 TYELLQ 602
Score = 32.7 bits (73), Expect = 0.44
Identities = 25/98 (25%), Positives = 43/98 (43%), Gaps = 8/98 (8%)
Query: 24 VSSKRDHRQVLSSLLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAK-----EAFRVLY 78
++ + H L+ L GA+AG A + V P D K QV+++ + FR +
Sbjct: 509 LADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKI- 567
Query: 79 YTYLNEGFLSLWRGNSATMVRVVPYAAIQFSAHEEYKR 116
EG + W+G +A + R P + +E +R
Sbjct: 568 --LREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQR 603
>gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Homo
sapiens]
Length = 325
Score = 83.2 bits (204), Expect = 3e-16
Identities = 73/283 (25%), Positives = 122/283 (43%), Gaps = 20/283 (7%)
Query: 40 GALAGALAKTAVAPLDRTKIIFQVSSKRFSAK-------EAFRVLYYTYLNEGFLSLWRG 92
G LA +A+ P+D TK QV + A+ F L+ EG L+L+ G
Sbjct: 47 GGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSG 106
Query: 93 NSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALAGTTAASLTYPL 152
+ ++R Y I+ ++ KR+ R E + G ++G ++++ P
Sbjct: 107 IAPALLRQASYGTIKIGIYQSLKRLFVE----RLEDETLLINMICGVVSGVISSTIANPT 162
Query: 153 DLVRARMAVTPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTYETLK 212
D+++ RM ++ FI I ++EG + L+ G +PT G+ Y+ K
Sbjct: 163 DVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITK 222
Query: 213 SLHREYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVRRRMQT----AGVTGYPRASIA 268
H SG + GL G AS P+DVVR RM G + ++
Sbjct: 223 K-HLILSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVD 281
Query: 269 RTLRTIVREEGAVRGLYKGLSMNWVK-GPIAVGISFTTFDLMQ 310
L+ + + EG LYKG NW++ GP + I F T++ ++
Sbjct: 282 GILK-MWKHEGFF-ALYKGFWPNWLRLGPWNI-IFFITYEQLK 321
Score = 79.3 bits (194), Expect = 4e-15
Identities = 59/213 (27%), Positives = 94/213 (44%), Gaps = 19/213 (8%)
Query: 104 AAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALAGTTAASLTYPLDLVRARMAVTP 163
AA+ S H++ + G W G LA A T+P+DL + R+ V
Sbjct: 19 AAVIVSGHQKSTTVSHEMSGLN------WKPFVYGGLASIVAEFGTFPVDLTKTRLQVQG 72
Query: 164 KEM--------YSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTYETLKSLH 215
+ + Y +FH RI +EEG+ LY G P +L Y + Y++LK L
Sbjct: 73 QSIDARFKEIKYRGMFHALFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLF 132
Query: 216 REYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVRRRMQTAGVTGYPRASIARTLRTIV 275
E MI G +G+I + + P DV++ RMQ G + S+ + I
Sbjct: 133 VE--RLEDETLLINMICGVVSGVISSTIANPTDVLKIRMQAQG--SLFQGSMIGSFIDIY 188
Query: 276 REEGAVRGLYKGLSMNWVKGPIAVGISFTTFDL 308
++EG RGL++G+ + I VG+ +D+
Sbjct: 189 QQEG-TRGLWRGVVPTAQRAAIVVGVELPVYDI 220
Score = 63.5 bits (153), Expect = 2e-10
Identities = 53/188 (28%), Positives = 82/188 (43%), Gaps = 11/188 (5%)
Query: 33 VLSSLLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYLNEGFLSLWRG 92
+L +++ G ++G ++ T P D KI Q F + Y EG LWRG
Sbjct: 141 LLINMICGVVSGVISSTIANPTDVLKIRMQAQGSLFQGSMIGSFIDI-YQQEGTRGLWRG 199
Query: 93 NSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEA-LPPWPRLFAGALAGTTAASLTYP 151
T R ++ ++ K+ L G G+ L + F LAG A++ P
Sbjct: 200 VVPTAQRAAIVVGVELPVYDITKKHL-ILSGMMGDTILTHFVSSFTCGLAGALASN---P 255
Query: 152 LDLVRARMA-----VTPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFF 206
+D+VR RM V ++Y +++ + EG LY GF P L + P+ + F
Sbjct: 256 VDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFI 315
Query: 207 TYETLKSL 214
TYE LK L
Sbjct: 316 TYEQLKRL 323
>gi|13259543 solute carrier family 25, member 14 isoform UCP5S [Homo
sapiens]
Length = 322
Score = 83.2 bits (204), Expect = 3e-16
Identities = 73/283 (25%), Positives = 122/283 (43%), Gaps = 20/283 (7%)
Query: 40 GALAGALAKTAVAPLDRTKIIFQVSSKRFSAK-------EAFRVLYYTYLNEGFLSLWRG 92
G LA +A+ P+D TK QV + A+ F L+ EG L+L+ G
Sbjct: 44 GGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSG 103
Query: 93 NSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALAGTTAASLTYPL 152
+ ++R Y I+ ++ KR+ R E + G ++G ++++ P
Sbjct: 104 IAPALLRQASYGTIKIGIYQSLKRLFVE----RLEDETLLINMICGVVSGVISSTIANPT 159
Query: 153 DLVRARMAVTPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTYETLK 212
D+++ RM ++ FI I ++EG + L+ G +PT G+ Y+ K
Sbjct: 160 DVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITK 219
Query: 213 SLHREYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVRRRMQT----AGVTGYPRASIA 268
H SG + GL G AS P+DVVR RM G + ++
Sbjct: 220 K-HLILSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVD 278
Query: 269 RTLRTIVREEGAVRGLYKGLSMNWVK-GPIAVGISFTTFDLMQ 310
L+ + + EG LYKG NW++ GP + I F T++ ++
Sbjct: 279 GILK-MWKHEGFF-ALYKGFWPNWLRLGPWNI-IFFITYEQLK 318
Score = 78.2 bits (191), Expect = 9e-15
Identities = 54/185 (29%), Positives = 85/185 (45%), Gaps = 13/185 (7%)
Query: 132 WPRLFAGALAGTTAASLTYPLDLVRARMAVTPKEM--------YSNIFHVFIRISREEGL 183
W G LA A T+P+DL + R+ V + + Y +FH RI +EEG+
Sbjct: 38 WKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGV 97
Query: 184 KTLYHGFMPTVLGVIPYAGLSFFTYETLKSLHREYSGRRQPYPFERMIFGACAGLIGQSA 243
LY G P +L Y + Y++LK L E MI G +G+I +
Sbjct: 98 LALYSGIAPALLRQASYGTIKIGIYQSLKRLFVE--RLEDETLLINMICGVVSGVISSTI 155
Query: 244 SYPLDVVRRRMQTAGVTGYPRASIARTLRTIVREEGAVRGLYKGLSMNWVKGPIAVGISF 303
+ P DV++ RMQ G + S+ + I ++EG RGL++G+ + I VG+
Sbjct: 156 ANPTDVLKIRMQAQG--SLFQGSMIGSFIDIYQQEG-TRGLWRGVVPTAQRAAIVVGVEL 212
Query: 304 TTFDL 308
+D+
Sbjct: 213 PVYDI 217
Score = 63.5 bits (153), Expect = 2e-10
Identities = 53/188 (28%), Positives = 82/188 (43%), Gaps = 11/188 (5%)
Query: 33 VLSSLLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYLNEGFLSLWRG 92
+L +++ G ++G ++ T P D KI Q F + Y EG LWRG
Sbjct: 138 LLINMICGVVSGVISSTIANPTDVLKIRMQAQGSLFQGSMIGSFIDI-YQQEGTRGLWRG 196
Query: 93 NSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEA-LPPWPRLFAGALAGTTAASLTYP 151
T R ++ ++ K+ L G G+ L + F LAG A++ P
Sbjct: 197 VVPTAQRAAIVVGVELPVYDITKKHL-ILSGMMGDTILTHFVSSFTCGLAGALASN---P 252
Query: 152 LDLVRARMA-----VTPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFF 206
+D+VR RM V ++Y +++ + EG LY GF P L + P+ + F
Sbjct: 253 VDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFI 312
Query: 207 TYETLKSL 214
TYE LK L
Sbjct: 313 TYEQLKRL 320
>gi|21314739 solute carrier family 25, member 32 [Homo sapiens]
Length = 315
Score = 81.3 bits (199), Expect = 1e-15
Identities = 76/296 (25%), Positives = 130/296 (43%), Gaps = 23/296 (7%)
Query: 36 SLLPGALAGALAKTAVAPLDRTKIIFQVSSK---RFSAKEAFRVLYYTYLNEGFLSLWRG 92
+L+ G G L+ A+ PLD KI F VS R L + +G L++G
Sbjct: 25 NLIAGVSGGVLSNLALHPLDLVKIRFAVSDGLELRPKYNGILHCLTTIWKLDGLRGLYQG 84
Query: 93 NSATMVRVVPYAAIQFSAHEEYKRILGSYYGF-RGEALPPWPRLFAGALAGTTAASLTYP 151
+ + A + + + + + SY R E L L + A AG +T P
Sbjct: 85 VTPNIWG----AGLSWGLYFFFYNAIKSYKTEGRAERLEATEYLVSAAEAGAMTLCITNP 140
Query: 152 LDLVRARMAV-------TPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLS 204
L + + R+ + +P Y +F ++I + EG++ LY GF+P + G + L
Sbjct: 141 LWVTKTRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEGVRGLYKGFVPGLFGT-SHGALQ 199
Query: 205 FFTYETLKSLHREYSGR---RQPYPFERMIFGACAGLIGQSASYPLDVVRRRMQTAGVTG 261
F YE LK + ++ R Q E + A + + +A+YP VVR R+Q +
Sbjct: 200 FMAYELLKLKYNQHINRLPEAQLSTVEYISVAALSKIFAVAATYPYQVVRARLQDQHMF- 258
Query: 262 YPRASIARTLRTIVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFDLMQIMLRHLQ 317
+ + + R+EG V G YKG++ N ++ A I+F ++ + L L+
Sbjct: 259 --YSGVIDVITKTWRKEG-VGGFYKGIAPNLIRVTPACCITFVVYENVSHFLLDLR 311
Score = 65.9 bits (159), Expect = 5e-11
Identities = 55/188 (29%), Positives = 84/188 (44%), Gaps = 10/188 (5%)
Query: 132 WPRLFAGALAGTTAASLTYPLDLVRARMAVTP----KEMYSNIFHVFIRISREEGLKTLY 187
+ L AG G + +PLDLV+ R AV+ + Y+ I H I + +GL+ LY
Sbjct: 23 YENLIAGVSGGVLSNLALHPLDLVKIRFAVSDGLELRPKYNGILHCLTTIWKLDGLRGLY 82
Query: 188 HGFMPTVLGVIPYAGLSFFTYETLKSLHREYSGRRQPYPFERMIFGACAGLIGQSASYPL 247
G P + G GL FF Y +KS E R E ++ A AG + + PL
Sbjct: 83 QGVTPNIWGAGLSWGLYFFFYNAIKSYKTEGRAERLE-ATEYLVSAAEAGAMTLCITNPL 141
Query: 248 DVVRRR--MQTAGVTGYPRASIARTLRTIVR--EEGAVRGLYKGLSMNWVKGPIAVGISF 303
V + R +Q V P T+V+ + VRGLYKG + + G + F
Sbjct: 142 WVTKTRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEGVRGLYKGF-VPGLFGTSHGALQF 200
Query: 304 TTFDLMQI 311
++L+++
Sbjct: 201 MAYELLKL 208
Score = 60.8 bits (146), Expect = 1e-09
Identities = 54/201 (26%), Positives = 86/201 (42%), Gaps = 9/201 (4%)
Query: 18 AVLSSSVSSKRDHRQVLSSLLPGALAGALAKTAVAPL--DRTKIIFQ----VSSKRFSAK 71
A+ S + + + L+ A AGA+ PL +T+++ Q V+S K
Sbjct: 105 AIKSYKTEGRAERLEATEYLVSAAEAGAMTLCITNPLWVTKTRLMLQYDAVVNSPHRQYK 164
Query: 72 EAFRVLYYTYLNEGFLSLWRGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEA-LP 130
F L Y EG L++G + + A+QF A+E K + EA L
Sbjct: 165 GMFDTLVKIYKYEGVRGLYKGFVPGLFGT-SHGALQFMAYELLKLKYNQHINRLPEAQLS 223
Query: 131 PWPRLFAGALAGTTAASLTYPLDLVRARMAVTPKEMYSNIFHVFIRISREEGLKTLYHGF 190
+ AL+ A + TYP +VRAR+ YS + V + R+EG+ Y G
Sbjct: 224 TVEYISVAALSKIFAVAATYPYQVVRARLQ-DQHMFYSGVIDVITKTWRKEGVGGFYKGI 282
Query: 191 MPTVLGVIPYAGLSFFTYETL 211
P ++ V P ++F YE +
Sbjct: 283 APNLIRVTPACCITFVVYENV 303
>gi|21389315 solute carrier family 25 (mitochondrial carrier;
citrate transporter), member 1 precursor [Homo sapiens]
Length = 311
Score = 79.3 bits (194), Expect = 4e-15
Identities = 73/280 (26%), Positives = 119/280 (42%), Gaps = 17/280 (6%)
Query: 36 SLLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFR----VLYYTYLNEGFLSLWR 91
++L G LAG + P + K Q+ + S +R + T + G L L+R
Sbjct: 28 AILAGGLAGGIEICITFPTEYVKTQLQLDER--SHPPRYRGIGDCVRQTVRSHGVLGLYR 85
Query: 92 GNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALAGTTAASLTY- 150
G S+ + +P AA++F E + G L L G AG A +
Sbjct: 86 GLSSLLYGSIPKAAVRFGMFEFLSNHMRDAQG----RLDSTRGLLCGLGAGVAEAVVVVC 141
Query: 151 PLDLVRARMA---VTPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFT 207
P++ ++ + +P Y FH I RE+GLK Y G TVL + FF
Sbjct: 142 PMETIKVKFIHDQTSPNPKYRGFFHGVREIVREQGLKGTYQGLTATVLKQGSNQAIRFFV 201
Query: 208 YETLKSLHREYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVRRRMQTAGVTGYPRASI 267
+L++ +R + + P +FGA AG + PLDV++ RMQ G+ + +
Sbjct: 202 MTSLRNWYRGDNPNKPMNPLITGVFGAIAGAASVFGNTPLDVIKTRMQ--GLEAHKYRNT 259
Query: 268 ARTLRTIVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFD 307
I+++EG ++ YKG + + V I F +D
Sbjct: 260 WDCGLQILKKEG-LKAFYKGTVPRLGRVCLDVAIVFVIYD 298
Score = 48.1 bits (113), Expect = 1e-05
Identities = 42/169 (24%), Positives = 75/169 (44%), Gaps = 8/169 (4%)
Query: 131 PWPRLFAGALAGTTAASLTYPLDLVRARMAVTPKE---MYSNIFHVFIRISREEGLKTLY 187
P + AG LAG +T+P + V+ ++ + + Y I + R G+ LY
Sbjct: 25 PGKAILAGGLAGGIEICITFPTEYVKTQLQLDERSHPPRYRGIGDCVRQTVRSHGVLGLY 84
Query: 188 HGFMPTVLGVIPYAGLSFFTYETLKSLHREYSGRRQPYPFERMIFGACAGLI-GQSASYP 246
G + G IP A + F +E L + R+ GR ++ G AG+ P
Sbjct: 85 RGLSSLLYGSIPKAAVRFGMFEFLSNHMRDAQGRLD--STRGLLCGLGAGVAEAVVVVCP 142
Query: 247 LDVVRRRMQTAGVTGYPR-ASIARTLRTIVREEGAVRGLYKGLSMNWVK 294
++ ++ + + P+ +R IVRE+G ++G Y+GL+ +K
Sbjct: 143 METIKVKFIHDQTSPNPKYRGFFHGVREIVREQG-LKGTYQGLTATVLK 190
Score = 48.1 bits (113), Expect = 1e-05
Identities = 49/200 (24%), Positives = 84/200 (42%), Gaps = 9/200 (4%)
Query: 20 LSSSVSSKRDHRQVLSSLLPGALAG-ALAKTAVAPLD--RTKIIFQVSSKRFSAKEAFRV 76
LS+ + + LL G AG A A V P++ + K I +S + F
Sbjct: 108 LSNHMRDAQGRLDSTRGLLCGLGAGVAEAVVVVCPMETIKVKFIHDQTSPNPKYRGFFHG 167
Query: 77 LYYTYLNEGFLSLWRGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLF 136
+ +G ++G +AT+++ AI+F L ++Y P P +
Sbjct: 168 VREIVREQGLKGTYQGLTATVLKQGSNQAIRFFVMTS----LRNWYRGDNPNKPMNPLIT 223
Query: 137 A--GALAGTTAASLTYPLDLVRARMAVTPKEMYSNIFHVFIRISREEGLKTLYHGFMPTV 194
GA+AG + PLD+++ RM Y N + ++I ++EGLK Y G +P +
Sbjct: 224 GVFGAIAGAASVFGNTPLDVIKTRMQGLEAHKYRNTWDCGLQILKKEGLKAFYKGTVPRL 283
Query: 195 LGVIPYAGLSFFTYETLKSL 214
V + F Y+ + L
Sbjct: 284 GRVCLDVAIVFVIYDEVVKL 303
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.137 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,582,893
Number of Sequences: 37866
Number of extensions: 415429
Number of successful extensions: 1427
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 64
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 884
Number of HSP's gapped (non-prelim): 219
length of query: 318
length of database: 18,247,518
effective HSP length: 102
effective length of query: 216
effective length of database: 14,385,186
effective search space: 3107200176
effective search space used: 3107200176
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.