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Search of human proteins with 6005956
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|6005956 dual specificity phosphatase 12 [Homo sapiens]
(340 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|6005956 dual specificity phosphatase 12 [Homo sapiens] 693 0.0
gi|75750526 dual specificity phosphatase 28 [Homo sapiens] 90 3e-18
gi|29826315 dual specificity phosphatase 15 isoform a [Homo sapi... 84 1e-16
gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo sapi... 84 1e-16
gi|9910432 dual specificity phosphatase 22 [Homo sapiens] 80 3e-15
gi|62865890 dual specificity phosphatase 5 [Homo sapiens] 77 2e-14
gi|239582767 slingshot homolog 3 [Homo sapiens] 74 1e-13
gi|4758204 dual specificity phosphatase 1 [Homo sapiens] 70 2e-12
gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens] 69 5e-12
gi|239047414 slingshot 1 isoform 1 [Homo sapiens] 68 1e-11
gi|239047498 slingshot 1 isoform 3 [Homo sapiens] 68 1e-11
gi|239047441 slingshot 1 isoform 2 [Homo sapiens] 68 1e-11
gi|4503421 dual specificity phosphatase 9 [Homo sapiens] 66 4e-11
gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens] 66 4e-11
gi|4758206 dual specificity phosphatase 2 [Homo sapiens] 66 5e-11
gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens] 65 7e-11
gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens] 65 7e-11
gi|38372911 dual specificity phosphatase 16 [Homo sapiens] 64 1e-10
gi|153281158 dual specificity phosphatase 8 [Homo sapiens] 64 3e-10
gi|37674210 slingshot 2 [Homo sapiens] 62 6e-10
gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo ... 62 7e-10
gi|194733759 serine/threonine/tyrosine interacting protein [Homo... 62 7e-10
gi|21687043 serine/threonine/tyrosine interacting protein [Homo ... 62 7e-10
gi|5902002 dual specificity phosphatase 14 [Homo sapiens] 61 1e-09
gi|56117818 muscle-restricted dual specificity phosphatase isofo... 60 2e-09
gi|238231453 dual specificity phosphatase 7 [Homo sapiens] 60 4e-09
gi|13128968 dual specificity phosphatase 26 [Homo sapiens] 60 4e-09
gi|21536333 dual specificity phosphatase 10 isoform b [Homo sapi... 59 5e-09
gi|21536331 dual specificity phosphatase 10 isoform b [Homo sapi... 59 5e-09
gi|214832050 dual specificity phosphatase 19 isoform 2 [Homo sap... 57 2e-08
>gi|6005956 dual specificity phosphatase 12 [Homo sapiens]
Length = 340
Score = 693 bits (1788), Expect = 0.0
Identities = 340/340 (100%), Positives = 340/340 (100%)
Query: 1 MLEAPGPSDGCELSNPSASRVSCAGQMLEVQPGLYFGGAAAVAEPDHLREAGITAVLTVD 60
MLEAPGPSDGCELSNPSASRVSCAGQMLEVQPGLYFGGAAAVAEPDHLREAGITAVLTVD
Sbjct: 1 MLEAPGPSDGCELSNPSASRVSCAGQMLEVQPGLYFGGAAAVAEPDHLREAGITAVLTVD 60
Query: 61 SEEPSFKAGPGVEDLWRLFVPALDKPETDLLSHLDRCVAFIGQARAEGRAVLVHCHAGVS 120
SEEPSFKAGPGVEDLWRLFVPALDKPETDLLSHLDRCVAFIGQARAEGRAVLVHCHAGVS
Sbjct: 61 SEEPSFKAGPGVEDLWRLFVPALDKPETDLLSHLDRCVAFIGQARAEGRAVLVHCHAGVS 120
Query: 121 RSVAIITAFLMKTDQLPFEKAYEKLQILKPEAKMNEGFEWQLKLYQAMGYEVDTSSAIYK 180
RSVAIITAFLMKTDQLPFEKAYEKLQILKPEAKMNEGFEWQLKLYQAMGYEVDTSSAIYK
Sbjct: 121 RSVAIITAFLMKTDQLPFEKAYEKLQILKPEAKMNEGFEWQLKLYQAMGYEVDTSSAIYK 180
Query: 181 QYRLQKVTEKYPELQNLPQELFAVDPTTVSQGLKDEVLYKCRKCRRSLFRSSSILDHREG 240
QYRLQKVTEKYPELQNLPQELFAVDPTTVSQGLKDEVLYKCRKCRRSLFRSSSILDHREG
Sbjct: 181 QYRLQKVTEKYPELQNLPQELFAVDPTTVSQGLKDEVLYKCRKCRRSLFRSSSILDHREG 240
Query: 241 SGPIAFAHKRMTPSSMLTTGRQAQCTSYFIEPVQWMESALLGVMDGQLLCPKCSAKLGSF 300
SGPIAFAHKRMTPSSMLTTGRQAQCTSYFIEPVQWMESALLGVMDGQLLCPKCSAKLGSF
Sbjct: 241 SGPIAFAHKRMTPSSMLTTGRQAQCTSYFIEPVQWMESALLGVMDGQLLCPKCSAKLGSF 300
Query: 301 NWYGEQCSCGRWITPAFQIHKNRVDEMKILPVLGSQTGKI 340
NWYGEQCSCGRWITPAFQIHKNRVDEMKILPVLGSQTGKI
Sbjct: 301 NWYGEQCSCGRWITPAFQIHKNRVDEMKILPVLGSQTGKI 340
>gi|75750526 dual specificity phosphatase 28 [Homo sapiens]
Length = 176
Score = 89.7 bits (221), Expect = 3e-18
Identities = 53/140 (37%), Positives = 78/140 (55%), Gaps = 4/140 (2%)
Query: 27 MLEVQPGLYFGGAAAVAEPDHLREAGITAVLTVDSEEPSFKAGPGVEDLWRLFVPALDKP 86
++ V P L+ G A A + L AG+T + V ++P +A PGV +L VP D P
Sbjct: 19 LVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPRA-PGVAELR---VPVFDDP 74
Query: 87 ETDLLSHLDRCVAFIGQARAEGRAVLVHCHAGVSRSVAIITAFLMKTDQLPFEKAYEKLQ 146
DLL+HL+ A + A G A LV+C G SRS A+ TA+LM+ L KA++ ++
Sbjct: 75 AEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSLAKAFQMVK 134
Query: 147 ILKPEAKMNEGFEWQLKLYQ 166
+P A+ N GF QL+ Y+
Sbjct: 135 SARPVAEPNPGFWSQLQKYE 154
>gi|29826315 dual specificity phosphatase 15 isoform a [Homo
sapiens]
Length = 235
Score = 84.3 bits (207), Expect = 1e-16
Identities = 48/137 (35%), Positives = 69/137 (50%), Gaps = 5/137 (3%)
Query: 27 MLEVQPGLYFGGAAAVAEPDHLREAGITAVLTVDSEEPSFKAGPGVEDLWRLFVPALDKP 86
M +V PGLY G + D L IT ++++ E P P ++D+ L +P D P
Sbjct: 5 MTKVLPGLYLGNFIDAKDLDQLGRNKITHIISIH-ESPQ----PLLQDITYLRIPVADTP 59
Query: 87 ETDLLSHLDRCVAFIGQARAEGRAVLVHCHAGVSRSVAIITAFLMKTDQLPFEKAYEKLQ 146
E + H C+ FI R G LVHC AG+SRS I+TA++M L + E ++
Sbjct: 60 EVPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIK 119
Query: 147 ILKPEAKMNEGFEWQLK 163
+P A N GF QL+
Sbjct: 120 ATRPIANPNPGFRQQLE 136
>gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo
sapiens]
Length = 217
Score = 84.3 bits (207), Expect = 1e-16
Identities = 54/163 (33%), Positives = 83/163 (50%), Gaps = 10/163 (6%)
Query: 5 PGPSDGCELSNPSASRVSCAGQMLEVQPGLYFGGAAAVAEPDHLREAGITAVLTVD-SEE 63
P GC +S + Q+ ++P L G A + D L++ +T +L V E
Sbjct: 48 PSSGGGCGYVQDLSSDL----QVGVIKPWLLLGSQDAAHDLDTLKKNKVTHILNVAYGVE 103
Query: 64 PSFKAGPGVEDLWRLFVPALDKPETDLLSHLDRCVAFIGQARAEGRAVLVHCHAGVSRSV 123
+F + D + LD PET++LS+ C FI +A+ + VLVHC+AGVSR+
Sbjct: 104 NAF-----LSDFTYKSISILDLPETNILSYFPECFEFIEEAKRKDGVVLVHCNAGVSRAA 158
Query: 124 AIITAFLMKTDQLPFEKAYEKLQILKPEAKMNEGFEWQLKLYQ 166
AI+ FLM ++Q F A+ ++ +P N GF QL+ YQ
Sbjct: 159 AIVIGFLMNSEQTSFTSAFSLVKNARPSICPNSGFMEQLRTYQ 201
>gi|9910432 dual specificity phosphatase 22 [Homo sapiens]
Length = 184
Score = 79.7 bits (195), Expect = 3e-15
Identities = 54/167 (32%), Positives = 84/167 (50%), Gaps = 15/167 (8%)
Query: 27 MLEVQPGLYFGGAAAVAEPDHLREAGITAVLTVDSEEPSFKAGPGVEDLWRLFVPALDKP 86
M ++ PGLY G + + L + +T +L+V A P +E + L +PA D P
Sbjct: 5 MNKILPGLYIGNFKDARDAEQLSKNKVTHILSVHDS-----ARPMLEGVKYLCIPAADSP 59
Query: 87 ETDLLSHLDRCVAFIGQARAEGRAVLVHCHAGVSRSVAIITAFLMKTDQLPFEKAYEKLQ 146
+L H + FI + R G + LVHC AGVSRSV ++ A++M +E A ++
Sbjct: 60 SQNLTRHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVR 119
Query: 147 ILKPEAKMNEGFEWQLKLYQAMGYEVDTSSAIYKQYRLQKVTEKYPE 193
+ A N GF+ QL+ ++ +EV QYR Q + E+Y E
Sbjct: 120 AGRSCANPNVGFQRQLQEFEK--HEV-------HQYR-QWLKEEYGE 156
>gi|62865890 dual specificity phosphatase 5 [Homo sapiens]
Length = 384
Score = 77.4 bits (189), Expect = 2e-14
Identities = 49/143 (34%), Positives = 71/143 (49%), Gaps = 4/143 (2%)
Query: 25 GQMLEVQPGLYFGGAAAVAEPDHLREAGITAVLTVDSEEPSFKAGPGVEDLWRLFVPALD 84
G +E+ P LY G A ++ + L ITA+L V S S + W +P D
Sbjct: 177 GGPVEILPFLYLGSAYHASKCEFLANLHITALLNV-SRRTSEACATHLHYKW---IPVED 232
Query: 85 KPETDLLSHLDRCVAFIGQARAEGRAVLVHCHAGVSRSVAIITAFLMKTDQLPFEKAYEK 144
D+ SH + FI R +G VLVHC AG+SRS I A+LMKT Q ++A++
Sbjct: 233 SHTADISSHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDY 292
Query: 145 LQILKPEAKMNEGFEWQLKLYQA 167
++ + N GF QL Y++
Sbjct: 293 IKQRRSMVSPNFGFMGQLLQYES 315
>gi|239582767 slingshot homolog 3 [Homo sapiens]
Length = 659
Score = 74.3 bits (181), Expect = 1e-13
Identities = 49/137 (35%), Positives = 68/137 (49%), Gaps = 4/137 (2%)
Query: 32 PGLYFGGAAAVAEPDHLREAGITAVLTVDSEEPSFKAGPGVEDLWRLFVPALDKPETDLL 91
P LY G A + L+ +T +L + E +F RL+ D+ LL
Sbjct: 334 PHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPERFTYHNVRLW----DEESAQLL 389
Query: 92 SHLDRCVAFIGQARAEGRAVLVHCHAGVSRSVAIITAFLMKTDQLPFEKAYEKLQILKPE 151
H FI ARA+G VLVHC GVSRS A + A+ MK + E+A +Q L+P
Sbjct: 390 PHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRPI 449
Query: 152 AKMNEGFEWQLKLYQAM 168
A+ N GF QL++YQ +
Sbjct: 450 ARPNPGFLRQLQIYQGI 466
>gi|4758204 dual specificity phosphatase 1 [Homo sapiens]
Length = 367
Score = 70.5 bits (171), Expect = 2e-12
Identities = 43/143 (30%), Positives = 71/143 (49%), Gaps = 4/143 (2%)
Query: 25 GQMLEVQPGLYFGGAAAVAEPDHLREAGITAVLTVDSEEPSFKAGPGVEDLWRLFVPALD 84
G +E+ P LY G A + D L GITA++ V + P+ G +P D
Sbjct: 172 GGPVEILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEG----HYQYKSIPVED 227
Query: 85 KPETDLLSHLDRCVAFIGQARAEGRAVLVHCHAGVSRSVAIITAFLMKTDQLPFEKAYEK 144
+ D+ S + + FI + G V VHC AG+SRS I A+LM+T+++ ++A+E
Sbjct: 228 NHKADISSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEF 287
Query: 145 LQILKPEAKMNEGFEWQLKLYQA 167
++ + N F QL +++
Sbjct: 288 VKQRRSIISPNFSFMGQLLQFES 310
>gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens]
Length = 381
Score = 69.3 bits (168), Expect = 5e-12
Identities = 51/155 (32%), Positives = 70/155 (45%), Gaps = 8/155 (5%)
Query: 8 SDGCELSNPSASRVSCAGQMLEVQPGLYFGGAAAVAEPDHLREAGITAVLTVDSEEPSFK 67
SDG LSN S +E+ P LY G A D L E GI +L V P+
Sbjct: 194 SDGSPLSNSQPSFP------VEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLF 247
Query: 68 AGPGVEDLWRLFVPALDKPETDLLSHLDRCVAFIGQARAEGRAVLVHCHAGVSRSVAIIT 127
G + +P D +L ++FI +AR + VLVHC AG+SRSV +
Sbjct: 248 ENAG--EFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTV 305
Query: 128 AFLMKTDQLPFEKAYEKLQILKPEAKMNEGFEWQL 162
A+LM+ L AY+ +++ K N F QL
Sbjct: 306 AYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQL 340
>gi|239047414 slingshot 1 isoform 1 [Homo sapiens]
Length = 1049
Score = 67.8 bits (164), Expect = 1e-11
Identities = 43/135 (31%), Positives = 66/135 (48%), Gaps = 4/135 (2%)
Query: 34 LYFGGAAAVAEPDHLREAGITAVLTVDSEEPSFKAGPGVEDLWRLFVPALDKPETDLLSH 93
LY G + + L+ +G+ +L V E +F G R++ D+ TDLL+H
Sbjct: 316 LYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVY----DEETTDLLAH 371
Query: 94 LDRCVAFIGQARAEGRAVLVHCHAGVSRSVAIITAFLMKTDQLPFEKAYEKLQILKPEAK 153
+ FI +A+ LVHC GVSRS + + A+ MK P EKAY ++ + +
Sbjct: 372 WNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITR 431
Query: 154 MNEGFEWQLKLYQAM 168
N GF QL Y+ +
Sbjct: 432 PNAGFMRQLSEYEGI 446
>gi|239047498 slingshot 1 isoform 3 [Homo sapiens]
Length = 703
Score = 67.8 bits (164), Expect = 1e-11
Identities = 43/135 (31%), Positives = 66/135 (48%), Gaps = 4/135 (2%)
Query: 34 LYFGGAAAVAEPDHLREAGITAVLTVDSEEPSFKAGPGVEDLWRLFVPALDKPETDLLSH 93
LY G + + L+ +G+ +L V E +F G R++ D+ TDLL+H
Sbjct: 327 LYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVY----DEETTDLLAH 382
Query: 94 LDRCVAFIGQARAEGRAVLVHCHAGVSRSVAIITAFLMKTDQLPFEKAYEKLQILKPEAK 153
+ FI +A+ LVHC GVSRS + + A+ MK P EKAY ++ + +
Sbjct: 383 WNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITR 442
Query: 154 MNEGFEWQLKLYQAM 168
N GF QL Y+ +
Sbjct: 443 PNAGFMRQLSEYEGI 457
>gi|239047441 slingshot 1 isoform 2 [Homo sapiens]
Length = 692
Score = 67.8 bits (164), Expect = 1e-11
Identities = 43/135 (31%), Positives = 66/135 (48%), Gaps = 4/135 (2%)
Query: 34 LYFGGAAAVAEPDHLREAGITAVLTVDSEEPSFKAGPGVEDLWRLFVPALDKPETDLLSH 93
LY G + + L+ +G+ +L V E +F G R++ D+ TDLL+H
Sbjct: 316 LYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVY----DEETTDLLAH 371
Query: 94 LDRCVAFIGQARAEGRAVLVHCHAGVSRSVAIITAFLMKTDQLPFEKAYEKLQILKPEAK 153
+ FI +A+ LVHC GVSRS + + A+ MK P EKAY ++ + +
Sbjct: 372 WNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITR 431
Query: 154 MNEGFEWQLKLYQAM 168
N GF QL Y+ +
Sbjct: 432 PNAGFMRQLSEYEGI 446
>gi|4503421 dual specificity phosphatase 9 [Homo sapiens]
Length = 384
Score = 66.2 bits (160), Expect = 4e-11
Identities = 51/163 (31%), Positives = 72/163 (44%), Gaps = 5/163 (3%)
Query: 3 EAPGPSDGCELSNPSASRVSC---AGQMLEVQPGLYFGGAAAVAEPDHLREAGITAVLTV 59
EA S C L + A+ A +++ P LY G A A + L + GI +L V
Sbjct: 177 EADRDSMSCGLDSEGATPPPVGLRASFPVQILPNLYLGSARDSANLESLAKLGIRYILNV 236
Query: 60 DSEEPSFKAGPGVEDLWRLFVPALDKPETDLLSHLDRCVAFIGQARAEGRAVLVHCHAGV 119
P+F G D +P D +L + FI +A ++ VLVHC AGV
Sbjct: 237 TPNLPNFFEKNG--DFHYKQIPISDHWSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGV 294
Query: 120 SRSVAIITAFLMKTDQLPFEKAYEKLQILKPEAKMNEGFEWQL 162
SRSV + A+LM+ L AY+ ++ K N F QL
Sbjct: 295 SRSVTVTVAYLMQKLHLSLNDAYDLVKRKKSNISPNFNFMGQL 337
>gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]
Length = 482
Score = 66.2 bits (160), Expect = 4e-11
Identities = 40/137 (29%), Positives = 68/137 (49%), Gaps = 2/137 (1%)
Query: 26 QMLEVQPGLYFGGAAAVAEPDHLREAGITAVLTVDSEEPSFKAGPGVEDLWRLFVPALDK 85
++ + P L+ G + D ++ I V+ V + P + G+ + RL PA D
Sbjct: 321 ELTPILPFLFLGNEQDAQDLDTMQRLNIGYVINVTTHLPLYHYEKGLFNYKRL--PATDS 378
Query: 86 PETDLLSHLDRCVAFIGQARAEGRAVLVHCHAGVSRSVAIITAFLMKTDQLPFEKAYEKL 145
+ +L + + FI +A G+ +L+HC AGVSRS I+ A+LMK ++ AY+ +
Sbjct: 379 NKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFV 438
Query: 146 QILKPEAKMNEGFEWQL 162
+ +P N F QL
Sbjct: 439 KGKRPIISPNLNFMGQL 455
>gi|4758206 dual specificity phosphatase 2 [Homo sapiens]
Length = 314
Score = 65.9 bits (159), Expect = 5e-11
Identities = 49/169 (28%), Positives = 84/169 (49%), Gaps = 10/169 (5%)
Query: 3 EAPGPS---DGCELS-NPSASRVSCAGQMLEVQPGLYFGGAAAVAEPDHLREAGITAVLT 58
EAP P+ G + S + S + V G +E+ P L+ G + ++ L+ GITAVL
Sbjct: 145 EAPAPALPPTGDKTSRSDSRAPVYDQGGPVEILPYLFLGSCSHSSDLQGLQACGITAVLN 204
Query: 59 VDSEEPSFKAGPGVEDLWRL-FVPALDKPETDLLSHLDRCVAFIGQARAEGRAVLVHCHA 117
V + P+ E L+R +P D ++ + + FI + G VLVHC A
Sbjct: 205 VSASCPNH-----FEGLFRYKSIPVEDNQMVEISAWFQEAIGFIDWVKNSGGRVLVHCQA 259
Query: 118 GVSRSVAIITAFLMKTDQLPFEKAYEKLQILKPEAKMNEGFEWQLKLYQ 166
G+SRS I A+LM++ ++ ++A++ ++ + N F QL ++
Sbjct: 260 GISRSATICLAYLMQSRRVRLDEAFDFVKQRRGVISPNFSFMGQLLQFE 308
>gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens]
Length = 394
Score = 65.5 bits (158), Expect = 7e-11
Identities = 45/143 (31%), Positives = 68/143 (47%), Gaps = 4/143 (2%)
Query: 25 GQMLEVQPGLYFGGAAAVAEPDHLREAGITAVLTVDSEEPSFKAGPGVEDLWRLFVPALD 84
G +E+ P LY G A A D L GITA+L V S+ P+ G +P D
Sbjct: 194 GGPVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEG----HYQYKCIPVED 249
Query: 85 KPETDLLSHLDRCVAFIGQARAEGRAVLVHCHAGVSRSVAIITAFLMKTDQLPFEKAYEK 144
+ D+ S + +I + VLVHC AG+SRS I A+LM ++ E+A+E
Sbjct: 250 NHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEF 309
Query: 145 LQILKPEAKMNEGFEWQLKLYQA 167
++ + N F QL +++
Sbjct: 310 VKQRRSIISPNFSFMGQLLQFES 332
>gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens]
Length = 303
Score = 65.5 bits (158), Expect = 7e-11
Identities = 45/143 (31%), Positives = 68/143 (47%), Gaps = 4/143 (2%)
Query: 25 GQMLEVQPGLYFGGAAAVAEPDHLREAGITAVLTVDSEEPSFKAGPGVEDLWRLFVPALD 84
G +E+ P LY G A A D L GITA+L V S+ P+ G +P D
Sbjct: 103 GGPVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEG----HYQYKCIPVED 158
Query: 85 KPETDLLSHLDRCVAFIGQARAEGRAVLVHCHAGVSRSVAIITAFLMKTDQLPFEKAYEK 144
+ D+ S + +I + VLVHC AG+SRS I A+LM ++ E+A+E
Sbjct: 159 NHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEF 218
Query: 145 LQILKPEAKMNEGFEWQLKLYQA 167
++ + N F QL +++
Sbjct: 219 VKQRRSIISPNFSFMGQLLQFES 241
>gi|38372911 dual specificity phosphatase 16 [Homo sapiens]
Length = 665
Score = 64.3 bits (155), Expect = 1e-10
Identities = 45/139 (32%), Positives = 68/139 (48%), Gaps = 7/139 (5%)
Query: 30 VQPGLYFGGAAAVAEPDHLREAGITAVLTVDSE--EPSFKAGPGVEDLWRLFVPALDKPE 87
+ P LY G V + +++ GI VL + +P F + + L VP D
Sbjct: 162 ILPNLYLGCQRDVLNKELMQQNGIGYVLNASNTCPKPDF-----IPESHFLRVPVNDSFC 216
Query: 88 TDLLSHLDRCVAFIGQARAEGRAVLVHCHAGVSRSVAIITAFLMKTDQLPFEKAYEKLQI 147
+L LD+ V FI +A+A VLVHC AG+SRS I A++MK + ++AY ++
Sbjct: 217 EKILPWLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKE 276
Query: 148 LKPEAKMNEGFEWQLKLYQ 166
+P N F QL Y+
Sbjct: 277 KRPTISPNFNFLGQLLDYE 295
>gi|153281158 dual specificity phosphatase 8 [Homo sapiens]
Length = 625
Score = 63.5 bits (153), Expect = 3e-10
Identities = 44/142 (30%), Positives = 68/142 (47%), Gaps = 7/142 (4%)
Query: 27 MLEVQPGLYFGGAAAVAEPDHLREAGITAVLTVDSE--EPSFKAGPGVEDLWRLFVPALD 84
+ + P LY G V D + + GI+ VL + +P F + + + VP D
Sbjct: 161 LTRILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPKPDF-----ICESRFMRVPIND 215
Query: 85 KPETDLLSHLDRCVAFIGQARAEGRAVLVHCHAGVSRSVAIITAFLMKTDQLPFEKAYEK 144
LL LD+ + FI +A+ V+VHC AG+SRS I A++MKT + + AY
Sbjct: 216 NYCEKLLPWLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRF 275
Query: 145 LQILKPEAKMNEGFEWQLKLYQ 166
++ +P N F QL Y+
Sbjct: 276 VKDRRPSISPNFNFLGQLLEYE 297
>gi|37674210 slingshot 2 [Homo sapiens]
Length = 1423
Score = 62.4 bits (150), Expect = 6e-10
Identities = 41/135 (30%), Positives = 68/135 (50%), Gaps = 4/135 (2%)
Query: 34 LYFGGAAAVAEPDHLREAGITAVLTVDSEEPSFKAGPGVEDLWRLFVPALDKPETDLLSH 93
++ G + + L+ G+ +L V E +F PGV + + V D+ TDLL++
Sbjct: 315 VFLGSEWNASNLEDLQNRGVRYILNVTREIDNFF--PGVFEYHNIRV--YDEEATDLLAY 370
Query: 94 LDRCVAFIGQARAEGRAVLVHCHAGVSRSVAIITAFLMKTDQLPFEKAYEKLQILKPEAK 153
+ FI +A+ G LVHC GVSRS + + A+ MK ++AY+ ++ + K
Sbjct: 371 WNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKERRTVTK 430
Query: 154 MNEGFEWQLKLYQAM 168
N F QL+ YQ +
Sbjct: 431 PNPSFMRQLEEYQGI 445
>gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo
sapiens]
Length = 223
Score = 62.0 bits (149), Expect = 7e-10
Identities = 42/146 (28%), Positives = 75/146 (51%), Gaps = 3/146 (2%)
Query: 26 QMLEVQPGLYFG--GAAAVAEPDHLREAGITAVLTVDSEEPSFKAGPGVEDLWR-LFVPA 82
+M E+ PGL+ G +A ++ L++ GIT ++ + + P + L+R L +
Sbjct: 28 EMQEILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDI 87
Query: 83 LDKPETDLLSHLDRCVAFIGQARAEGRAVLVHCHAGVSRSVAIITAFLMKTDQLPFEKAY 142
D P +++ FI + G VLVH +AG+SRS A + A++M+T + + A+
Sbjct: 88 ADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAF 147
Query: 143 EKLQILKPEAKMNEGFEWQLKLYQAM 168
+Q + N GF QL+ Y+A+
Sbjct: 148 AYVQERRFCINPNAGFVHQLQEYEAI 173
>gi|194733759 serine/threonine/tyrosine interacting protein [Homo
sapiens]
Length = 223
Score = 62.0 bits (149), Expect = 7e-10
Identities = 42/146 (28%), Positives = 75/146 (51%), Gaps = 3/146 (2%)
Query: 26 QMLEVQPGLYFG--GAAAVAEPDHLREAGITAVLTVDSEEPSFKAGPGVEDLWR-LFVPA 82
+M E+ PGL+ G +A ++ L++ GIT ++ + + P + L+R L +
Sbjct: 28 EMQEILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDI 87
Query: 83 LDKPETDLLSHLDRCVAFIGQARAEGRAVLVHCHAGVSRSVAIITAFLMKTDQLPFEKAY 142
D P +++ FI + G VLVH +AG+SRS A + A++M+T + + A+
Sbjct: 88 ADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAF 147
Query: 143 EKLQILKPEAKMNEGFEWQLKLYQAM 168
+Q + N GF QL+ Y+A+
Sbjct: 148 AYVQERRFCINPNAGFVHQLQEYEAI 173
>gi|21687043 serine/threonine/tyrosine interacting protein [Homo
sapiens]
Length = 223
Score = 62.0 bits (149), Expect = 7e-10
Identities = 42/146 (28%), Positives = 75/146 (51%), Gaps = 3/146 (2%)
Query: 26 QMLEVQPGLYFG--GAAAVAEPDHLREAGITAVLTVDSEEPSFKAGPGVEDLWR-LFVPA 82
+M E+ PGL+ G +A ++ L++ GIT ++ + + P + L+R L +
Sbjct: 28 EMQEILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDI 87
Query: 83 LDKPETDLLSHLDRCVAFIGQARAEGRAVLVHCHAGVSRSVAIITAFLMKTDQLPFEKAY 142
D P +++ FI + G VLVH +AG+SRS A + A++M+T + + A+
Sbjct: 88 ADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAF 147
Query: 143 EKLQILKPEAKMNEGFEWQLKLYQAM 168
+Q + N GF QL+ Y+A+
Sbjct: 148 AYVQERRFCINPNAGFVHQLQEYEAI 173
>gi|5902002 dual specificity phosphatase 14 [Homo sapiens]
Length = 198
Score = 61.2 bits (147), Expect = 1e-09
Identities = 44/162 (27%), Positives = 68/162 (41%), Gaps = 12/162 (7%)
Query: 25 GQMLEVQPGLYFGGAAAVAEPDHLREAGITAVLTVDSEEPSFKAGPGVEDLWRLF----V 80
G + ++ L+ G + + L+ GIT ++ E P+F W F V
Sbjct: 25 GGIAQITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNFN--------WPQFEYVKV 76
Query: 81 PALDKPETDLLSHLDRCVAFIGQARAEGRAVLVHCHAGVSRSVAIITAFLMKTDQLPFEK 140
P D P + + D I + A LVHC AGVSRS + A+LMK + +
Sbjct: 77 PLADMPHAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLE 136
Query: 141 AYEKLQILKPEAKMNEGFEWQLKLYQAMGYEVDTSSAIYKQY 182
AY ++ +P + N GF QL Y+ + T + Y
Sbjct: 137 AYNWVKARRPVIRPNVGFWRQLIDYERQLFGKSTVKMVQTPY 178
>gi|56117818 muscle-restricted dual specificity phosphatase isoform
1 [Homo sapiens]
Length = 188
Score = 60.5 bits (145), Expect = 2e-09
Identities = 44/127 (34%), Positives = 63/127 (49%), Gaps = 4/127 (3%)
Query: 18 ASRVSCAGQMLEVQPGLYFGGAAAVAEPDHLREAGITAVLTVDSEEPSFKAGPGV--EDL 75
A + SC+ ++ EV P L+ G AA L + GIT VL + + GP +
Sbjct: 30 AGKSSCS-RVDEVWPNLFIGDAATANNRFELWKLGITHVLNAAHKGLYCQGGPDFYGSSV 88
Query: 76 WRLFVPALDKPETDLLSHLDRCVAFIGQA-RAEGRAVLVHCHAGVSRSVAIITAFLMKTD 134
L VPA D P+ D+ ++ FI +A G VLVHC GVSRS ++ A+LM
Sbjct: 89 SYLGVPAHDLPDFDISAYFSSAADFIHRALNTPGAKVLVHCVVGVSRSATLVLAYLMLHQ 148
Query: 135 QLPFEKA 141
+L +A
Sbjct: 149 RLSLRQA 155
>gi|238231453 dual specificity phosphatase 7 [Homo sapiens]
Length = 419
Score = 59.7 bits (143), Expect = 4e-09
Identities = 42/135 (31%), Positives = 63/135 (46%), Gaps = 2/135 (1%)
Query: 28 LEVQPGLYFGGAAAVAEPDHLREAGITAVLTVDSEEPSFKAGPGVEDLWRLFVPALDKPE 87
+++ P LY G A D L + GI +L V P+ G + +P D
Sbjct: 246 VQILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGG--EFTYKQIPISDHWS 303
Query: 88 TDLLSHLDRCVAFIGQARAEGRAVLVHCHAGVSRSVAIITAFLMKTDQLPFEKAYEKLQI 147
+L ++FI +AR++ VLVHC AG+SRSV + A+LM+ L AY+ ++
Sbjct: 304 QNLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKR 363
Query: 148 LKPEAKMNEGFEWQL 162
K N F QL
Sbjct: 364 KKSNISPNFNFMGQL 378
>gi|13128968 dual specificity phosphatase 26 [Homo sapiens]
Length = 211
Score = 59.7 bits (143), Expect = 4e-09
Identities = 43/123 (34%), Positives = 56/123 (45%), Gaps = 8/123 (6%)
Query: 29 EVQPGLYFGGAAAVAEPDHLREAGITAVLTVDSEE----PSFKAGPGVEDLWRLFVPALD 84
EV PGLY G LR GIT VL P G G+ L V A D
Sbjct: 64 EVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLG---VEAHD 120
Query: 85 KPETDLLSHLDRCVAFIGQARAE-GRAVLVHCHAGVSRSVAIITAFLMKTDQLPFEKAYE 143
P D+ H FI +A ++ G +LVHC GVSRS ++ A+LM L +A +
Sbjct: 121 SPAFDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIK 180
Query: 144 KLQ 146
K++
Sbjct: 181 KVK 183
>gi|21536333 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 59.3 bits (142), Expect = 5e-09
Identities = 36/115 (31%), Positives = 59/115 (51%), Gaps = 2/115 (1%)
Query: 48 LREAGITAVLTVDSEEPSFKAGPGVEDLWRLFVPALDKPETDLLSHLDRCVAFIGQARAE 107
++ I V+ V + P + G+ + RL PA D + +L + + FI +A
Sbjct: 1 MQRLNIGYVINVTTHLPLYHYEKGLFNYKRL--PATDSNKQNLRQYFEEAFEFIEEAHQC 58
Query: 108 GRAVLVHCHAGVSRSVAIITAFLMKTDQLPFEKAYEKLQILKPEAKMNEGFEWQL 162
G+ +L+HC AGVSRS I+ A+LMK ++ AY+ ++ +P N F QL
Sbjct: 59 GKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQL 113
>gi|21536331 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 59.3 bits (142), Expect = 5e-09
Identities = 36/115 (31%), Positives = 59/115 (51%), Gaps = 2/115 (1%)
Query: 48 LREAGITAVLTVDSEEPSFKAGPGVEDLWRLFVPALDKPETDLLSHLDRCVAFIGQARAE 107
++ I V+ V + P + G+ + RL PA D + +L + + FI +A
Sbjct: 1 MQRLNIGYVINVTTHLPLYHYEKGLFNYKRL--PATDSNKQNLRQYFEEAFEFIEEAHQC 58
Query: 108 GRAVLVHCHAGVSRSVAIITAFLMKTDQLPFEKAYEKLQILKPEAKMNEGFEWQL 162
G+ +L+HC AGVSRS I+ A+LMK ++ AY+ ++ +P N F QL
Sbjct: 59 GKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQL 113
>gi|214832050 dual specificity phosphatase 19 isoform 2 [Homo
sapiens]
Length = 166
Score = 57.4 bits (137), Expect = 2e-08
Identities = 40/109 (36%), Positives = 55/109 (50%), Gaps = 2/109 (1%)
Query: 59 VDSEEPSFKAGPG-VEDLWRLFVPALDKPETDLLSHLDRCVAFIGQARAEGRAVLVHCHA 117
V+ EPS G G V+DL + KP LL D + + VLVHC+A
Sbjct: 43 VEEVEPSSGGGCGYVQDLSSDLQVGVIKPWL-LLGSQDAAHDLDTLKKNKDGVVLVHCNA 101
Query: 118 GVSRSVAIITAFLMKTDQLPFEKAYEKLQILKPEAKMNEGFEWQLKLYQ 166
GVSR+ AI+ FLM ++Q F A+ ++ +P N GF QL+ YQ
Sbjct: 102 GVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPSICPNSGFMEQLRTYQ 150
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,025,757
Number of Sequences: 37866
Number of extensions: 629495
Number of successful extensions: 4289
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 80
Number of HSP's successfully gapped in prelim test: 31
Number of HSP's that attempted gapping in prelim test: 3987
Number of HSP's gapped (non-prelim): 315
length of query: 340
length of database: 18,247,518
effective HSP length: 103
effective length of query: 237
effective length of database: 14,347,320
effective search space: 3400314840
effective search space used: 3400314840
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.