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Search of human proteins with 5902082
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5902082 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
[Homo sapiens]
(350 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5902082 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [H... 742 0.0
gi|27765096 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [... 359 2e-99
gi|4506951 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [H... 359 2e-99
gi|28373086 sialyltransferase 6 isoform i [Homo sapiens] 104 1e-22
gi|28373082 sialyltransferase 6 isoform g [Homo sapiens] 104 1e-22
gi|28373078 sialyltransferase 6 isoform f [Homo sapiens] 104 1e-22
gi|28373070 sialyltransferase 6 isoform b [Homo sapiens] 104 1e-22
gi|28373068 sialyltransferase 6 isoform a [Homo sapiens] 104 1e-22
gi|5454060 sialyltransferase 6 isoform j [Homo sapiens] 104 1e-22
gi|5454058 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [H... 103 3e-22
gi|192448440 sialyltransferase 7B [Homo sapiens] 97 3e-20
gi|109633046 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 ... 92 5e-19
gi|109633044 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 ... 92 5e-19
gi|5174697 alpha2,3-sialyltransferase VI [Homo sapiens] 89 6e-18
gi|28373092 sialyltransferase 7D isoform a [Homo sapiens] 85 8e-17
gi|21264332 sialyltransferase 7A [Homo sapiens] 81 1e-15
gi|28373074 sialyltransferase 6 isoform d [Homo sapiens] 78 1e-14
gi|5031999 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransf... 78 1e-14
gi|110815855 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltran... 73 3e-13
gi|5174677 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransf... 73 4e-13
gi|4506953 alpha-2,8-sialyltransferase 1 [Homo sapiens] 70 3e-12
gi|4506949 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 i... 69 6e-12
gi|27765091 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 ... 69 6e-12
gi|28373094 sialyltransferase 7D isoform b [Homo sapiens] 67 3e-11
gi|229892273 sialyltransferase 7C isoform 1 [Homo sapiens] 65 9e-11
gi|28373101 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltrans... 63 3e-10
gi|215272345 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2... 62 1e-09
gi|26190610 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 ... 62 1e-09
gi|13569938 sialyltransferase 7E [Homo sapiens] 61 2e-09
gi|21361444 sialytransferase 7F [Homo sapiens] 60 4e-09
>gi|5902082 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [Homo
sapiens]
Length = 350
Score = 742 bits (1916), Expect = 0.0
Identities = 350/350 (100%), Positives = 350/350 (100%)
Query: 1 MKCSLRVWFLSVAFLLVFIMSLLFTYSHHSMATLPYLDSGALDGTHRVKLVPGYAGLQRL 60
MKCSLRVWFLSVAFLLVFIMSLLFTYSHHSMATLPYLDSGALDGTHRVKLVPGYAGLQRL
Sbjct: 1 MKCSLRVWFLSVAFLLVFIMSLLFTYSHHSMATLPYLDSGALDGTHRVKLVPGYAGLQRL 60
Query: 61 SKERLSGKSCACRRCMGDAGASDWFDSHFDGNISPVWTRENMDLPPDVQRWWMMLQPQFK 120
SKERLSGKSCACRRCMGDAGASDWFDSHFDGNISPVWTRENMDLPPDVQRWWMMLQPQFK
Sbjct: 61 SKERLSGKSCACRRCMGDAGASDWFDSHFDGNISPVWTRENMDLPPDVQRWWMMLQPQFK 120
Query: 121 SHNTNEVLEKLFQIVPGENPYRFRDPHQCRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMN 180
SHNTNEVLEKLFQIVPGENPYRFRDPHQCRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMN
Sbjct: 121 SHNTNEVLEKLFQIVPGENPYRFRDPHQCRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMN 180
Query: 181 QAPTVGFEQDVGSRTTHHFMYPESAKNLPANVSFVLVPFKVLDLLWIASALSTGQIRFTY 240
QAPTVGFEQDVGSRTTHHFMYPESAKNLPANVSFVLVPFKVLDLLWIASALSTGQIRFTY
Sbjct: 181 QAPTVGFEQDVGSRTTHHFMYPESAKNLPANVSFVLVPFKVLDLLWIASALSTGQIRFTY 240
Query: 241 APVKSFLRVDKEKVQIYNPAFFKYIHDRWTEHHGRYPSTGMLVLFFALHVCDEVNVYGFG 300
APVKSFLRVDKEKVQIYNPAFFKYIHDRWTEHHGRYPSTGMLVLFFALHVCDEVNVYGFG
Sbjct: 241 APVKSFLRVDKEKVQIYNPAFFKYIHDRWTEHHGRYPSTGMLVLFFALHVCDEVNVYGFG 300
Query: 301 ADSRGNWHHYWENNRYAGEFRKTGVHDADFEAHIIDMLAKASKIEVYRGN 350
ADSRGNWHHYWENNRYAGEFRKTGVHDADFEAHIIDMLAKASKIEVYRGN
Sbjct: 301 ADSRGNWHHYWENNRYAGEFRKTGVHDADFEAHIIDMLAKASKIEVYRGN 350
>gi|27765096 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
[Homo sapiens]
Length = 340
Score = 359 bits (921), Expect = 2e-99
Identities = 168/341 (49%), Positives = 229/341 (67%), Gaps = 14/341 (4%)
Query: 10 LSVAFLLVFIMSLLFTYSHHSMATLPYLDSGALDGTHRVKLVPGYAGLQRLSKERLSGKS 69
L+ L +F+ S YSH +AT + L+ + +K RL K R
Sbjct: 12 LTFLVLFIFLTSFFLNYSHTMVATTWFPKQMVLELSENLK---------RLIKHR----P 58
Query: 70 CACRRCMGDAGASDWFDSHFDGNISPVWTRENMDLPPDVQRWWMMLQPQFKSHNTNEVLE 129
C C C+G S WFD F+ + P+ T +N L D RWW+ LQ + K +N N+ ++
Sbjct: 59 CTCTHCIGQRKLSAWFDERFNQTMQPLLTAQNALLEDDTYRWWLRLQREKKPNNLNDTIK 118
Query: 130 KLFQIVPGE-NPYRFRDPHQCRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAPTVGFE 188
+LF++VPG +P + CRRCAVVGNSGNLR S YG ++D H+F++RMN+APT GFE
Sbjct: 119 ELFRVVPGNVDPMLEKRSVGCRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGFE 178
Query: 189 QDVGSRTTHHFMYPESAKNLPANVSFVLVPFKVLDLLWIASALSTGQIRFTYAPVKSFLR 248
DVG++TTHH +YPES + L NVS +LVPFK +DL W+ SA++TG I TY PV + +R
Sbjct: 179 ADVGTKTTHHLVYPESFRELGDNVSMILVPFKTIDLEWVVSAITTGTISHTYIPVPAKIR 238
Query: 249 VDKEKVQIYNPAFFKYIHDRWTEHHGRYPSTGMLVLFFALHVCDEVNVYGFGADSRGNWH 308
V ++K+ IY+PAF KY+ D W + HGRYPSTG+L + F++HVCDEV++YGFGADS+GNWH
Sbjct: 239 VKQDKILIYHPAFIKYVFDNWLQGHGRYPSTGILSVIFSMHVCDEVDLYGFGADSKGNWH 298
Query: 309 HYWENNRYAGEFRKTGVHDADFEAHIIDMLAKASKIEVYRG 349
HYWENN AG FRKTGVHDADFE+++ LA +KI +++G
Sbjct: 299 HYWENNPSAGAFRKTGVHDADFESNVTATLASINKIRIFKG 339
>gi|4506951 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [Homo
sapiens]
Length = 340
Score = 359 bits (921), Expect = 2e-99
Identities = 168/341 (49%), Positives = 229/341 (67%), Gaps = 14/341 (4%)
Query: 10 LSVAFLLVFIMSLLFTYSHHSMATLPYLDSGALDGTHRVKLVPGYAGLQRLSKERLSGKS 69
L+ L +F+ S YSH +AT + L+ + +K RL K R
Sbjct: 12 LTFLVLFIFLTSFFLNYSHTMVATTWFPKQMVLELSENLK---------RLIKHR----P 58
Query: 70 CACRRCMGDAGASDWFDSHFDGNISPVWTRENMDLPPDVQRWWMMLQPQFKSHNTNEVLE 129
C C C+G S WFD F+ + P+ T +N L D RWW+ LQ + K +N N+ ++
Sbjct: 59 CTCTHCIGQRKLSAWFDERFNQTMQPLLTAQNALLEDDTYRWWLRLQREKKPNNLNDTIK 118
Query: 130 KLFQIVPGE-NPYRFRDPHQCRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAPTVGFE 188
+LF++VPG +P + CRRCAVVGNSGNLR S YG ++D H+F++RMN+APT GFE
Sbjct: 119 ELFRVVPGNVDPMLEKRSVGCRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGFE 178
Query: 189 QDVGSRTTHHFMYPESAKNLPANVSFVLVPFKVLDLLWIASALSTGQIRFTYAPVKSFLR 248
DVG++TTHH +YPES + L NVS +LVPFK +DL W+ SA++TG I TY PV + +R
Sbjct: 179 ADVGTKTTHHLVYPESFRELGDNVSMILVPFKTIDLEWVVSAITTGTISHTYIPVPAKIR 238
Query: 249 VDKEKVQIYNPAFFKYIHDRWTEHHGRYPSTGMLVLFFALHVCDEVNVYGFGADSRGNWH 308
V ++K+ IY+PAF KY+ D W + HGRYPSTG+L + F++HVCDEV++YGFGADS+GNWH
Sbjct: 239 VKQDKILIYHPAFIKYVFDNWLQGHGRYPSTGILSVIFSMHVCDEVDLYGFGADSKGNWH 298
Query: 309 HYWENNRYAGEFRKTGVHDADFEAHIIDMLAKASKIEVYRG 349
HYWENN AG FRKTGVHDADFE+++ LA +KI +++G
Sbjct: 299 HYWENNPSAGAFRKTGVHDADFESNVTATLASINKIRIFKG 339
>gi|28373086 sialyltransferase 6 isoform i [Homo sapiens]
Length = 413
Score = 104 bits (260), Expect = 1e-22
Identities = 75/217 (34%), Positives = 104/217 (47%), Gaps = 18/217 (8%)
Query: 145 DPHQCRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAPTVGFEQDVGSRTTHHFMYPES 204
D +CRRC +VGN G L G +D ++ ++R+N AP GFE+DVGS+TT YPE
Sbjct: 191 DSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEG 250
Query: 205 AKNLPANVS----FVLVPFKVLDLLWIASALSTGQIRFTYAPVKSF-LRVDKE--KVQIY 257
A P FVL FK D W+ + ++ + KS RV KE +++I
Sbjct: 251 AMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRIL 310
Query: 258 NPAFFKYI--------HDRWTEHHGRYPSTGMLVLFFALHVCDEVNVYGFGAD-SRGNWH 308
NP F + + G P+ G + + ALH CDEV V GFG D S N
Sbjct: 311 NPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAP 370
Query: 309 -HYWENNRYAGEFRKTGVHDADFEAHIIDMLAKASKI 344
HY+E R A +++ H+ E + L KA I
Sbjct: 371 LHYYETVRMAA-IKESWTHNIQREKEFLRKLVKARVI 406
>gi|28373082 sialyltransferase 6 isoform g [Homo sapiens]
Length = 359
Score = 104 bits (260), Expect = 1e-22
Identities = 75/217 (34%), Positives = 104/217 (47%), Gaps = 18/217 (8%)
Query: 145 DPHQCRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAPTVGFEQDVGSRTTHHFMYPES 204
D +CRRC +VGN G L G +D ++ ++R+N AP GFE+DVGS+TT YPE
Sbjct: 137 DSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEG 196
Query: 205 AKNLPANVS----FVLVPFKVLDLLWIASALSTGQIRFTYAPVKSF-LRVDKE--KVQIY 257
A P FVL FK D W+ + ++ + KS RV KE +++I
Sbjct: 197 AMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRIL 256
Query: 258 NPAFFKYI--------HDRWTEHHGRYPSTGMLVLFFALHVCDEVNVYGFGAD-SRGNWH 308
NP F + + G P+ G + + ALH CDEV V GFG D S N
Sbjct: 257 NPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAP 316
Query: 309 -HYWENNRYAGEFRKTGVHDADFEAHIIDMLAKASKI 344
HY+E R A +++ H+ E + L KA I
Sbjct: 317 LHYYETVRMAA-IKESWTHNIQREKEFLRKLVKARVI 352
>gi|28373078 sialyltransferase 6 isoform f [Homo sapiens]
Length = 429
Score = 104 bits (260), Expect = 1e-22
Identities = 75/217 (34%), Positives = 104/217 (47%), Gaps = 18/217 (8%)
Query: 145 DPHQCRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAPTVGFEQDVGSRTTHHFMYPES 204
D +CRRC +VGN G L G +D ++ ++R+N AP GFE+DVGS+TT YPE
Sbjct: 207 DSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEG 266
Query: 205 AKNLPANVS----FVLVPFKVLDLLWIASALSTGQIRFTYAPVKSF-LRVDKE--KVQIY 257
A P FVL FK D W+ + ++ + KS RV KE +++I
Sbjct: 267 AMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRIL 326
Query: 258 NPAFFKYI--------HDRWTEHHGRYPSTGMLVLFFALHVCDEVNVYGFGAD-SRGNWH 308
NP F + + G P+ G + + ALH CDEV V GFG D S N
Sbjct: 327 NPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAP 386
Query: 309 -HYWENNRYAGEFRKTGVHDADFEAHIIDMLAKASKI 344
HY+E R A +++ H+ E + L KA I
Sbjct: 387 LHYYETVRMAA-IKESWTHNIQREKEFLRKLVKARVI 422
>gi|28373070 sialyltransferase 6 isoform b [Homo sapiens]
Length = 390
Score = 104 bits (260), Expect = 1e-22
Identities = 75/217 (34%), Positives = 104/217 (47%), Gaps = 18/217 (8%)
Query: 145 DPHQCRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAPTVGFEQDVGSRTTHHFMYPES 204
D +CRRC +VGN G L G +D ++ ++R+N AP GFE+DVGS+TT YPE
Sbjct: 168 DSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEG 227
Query: 205 AKNLPANVS----FVLVPFKVLDLLWIASALSTGQIRFTYAPVKSF-LRVDKE--KVQIY 257
A P FVL FK D W+ + ++ + KS RV KE +++I
Sbjct: 228 AMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRIL 287
Query: 258 NPAFFKYI--------HDRWTEHHGRYPSTGMLVLFFALHVCDEVNVYGFGAD-SRGNWH 308
NP F + + G P+ G + + ALH CDEV V GFG D S N
Sbjct: 288 NPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAP 347
Query: 309 -HYWENNRYAGEFRKTGVHDADFEAHIIDMLAKASKI 344
HY+E R A +++ H+ E + L KA I
Sbjct: 348 LHYYETVRMAA-IKESWTHNIQREKEFLRKLVKARVI 383
>gi|28373068 sialyltransferase 6 isoform a [Homo sapiens]
Length = 444
Score = 104 bits (260), Expect = 1e-22
Identities = 75/217 (34%), Positives = 104/217 (47%), Gaps = 18/217 (8%)
Query: 145 DPHQCRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAPTVGFEQDVGSRTTHHFMYPES 204
D +CRRC +VGN G L G +D ++ ++R+N AP GFE+DVGS+TT YPE
Sbjct: 222 DSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEG 281
Query: 205 AKNLPANVS----FVLVPFKVLDLLWIASALSTGQIRFTYAPVKSF-LRVDKE--KVQIY 257
A P FVL FK D W+ + ++ + KS RV KE +++I
Sbjct: 282 AMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRIL 341
Query: 258 NPAFFKYI--------HDRWTEHHGRYPSTGMLVLFFALHVCDEVNVYGFGAD-SRGNWH 308
NP F + + G P+ G + + ALH CDEV V GFG D S N
Sbjct: 342 NPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAP 401
Query: 309 -HYWENNRYAGEFRKTGVHDADFEAHIIDMLAKASKI 344
HY+E R A +++ H+ E + L KA I
Sbjct: 402 LHYYETVRMAA-IKESWTHNIQREKEFLRKLVKARVI 437
>gi|5454060 sialyltransferase 6 isoform j [Homo sapiens]
Length = 375
Score = 104 bits (260), Expect = 1e-22
Identities = 75/217 (34%), Positives = 104/217 (47%), Gaps = 18/217 (8%)
Query: 145 DPHQCRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAPTVGFEQDVGSRTTHHFMYPES 204
D +CRRC +VGN G L G +D ++ ++R+N AP GFE+DVGS+TT YPE
Sbjct: 153 DSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEG 212
Query: 205 AKNLPANVS----FVLVPFKVLDLLWIASALSTGQIRFTYAPVKSF-LRVDKE--KVQIY 257
A P FVL FK D W+ + ++ + KS RV KE +++I
Sbjct: 213 AMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRIL 272
Query: 258 NPAFFKYI--------HDRWTEHHGRYPSTGMLVLFFALHVCDEVNVYGFGAD-SRGNWH 308
NP F + + G P+ G + + ALH CDEV V GFG D S N
Sbjct: 273 NPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAP 332
Query: 309 -HYWENNRYAGEFRKTGVHDADFEAHIIDMLAKASKI 344
HY+E R A +++ H+ E + L KA I
Sbjct: 333 LHYYETVRMAA-IKESWTHNIQREKEFLRKLVKARVI 368
>gi|5454058 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [Homo
sapiens]
Length = 329
Score = 103 bits (256), Expect = 3e-22
Identities = 64/182 (35%), Positives = 98/182 (53%), Gaps = 17/182 (9%)
Query: 148 QCRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAPTVGFEQDVGSRTTHHFMYPESAKN 207
+CRRC VVGN LR S G ++ ++ ++R+N AP G+E DVGS+TT YPESA
Sbjct: 112 RCRRCVVVGNGHRLRNSSLGDAINKYDVVIRLNNAPVAGYEGDVGSKTTMRLFYPESAHF 171
Query: 208 LP-----ANVSFVLVPFKVLDLLWIASALS-TGQIRFTYAPVKSFL-RVDKEKVQIYNPA 260
P + VLV FK +D WI + LS ++R + + V+ ++++I NP
Sbjct: 172 DPKVENNPDTLLVLVAFKAMDFHWIETILSDKKRVRKGFWKQPPLIWDVNPKQIRILNPF 231
Query: 261 FFKYIHDR-------WTEHHGRYPSTGMLVLFFALHVCDEVNVYGFG---ADSRGNWHHY 310
F + D+ + P+TG+L + ALH+CD V++ GFG A ++ HY
Sbjct: 232 FMEIAADKLLSLPMQQPRKIKQKPTTGLLAITLALHLCDLVHIAGFGYPDAYNKKQTIHY 291
Query: 311 WE 312
+E
Sbjct: 292 YE 293
>gi|192448440 sialyltransferase 7B [Homo sapiens]
Length = 374
Score = 96.7 bits (239), Expect = 3e-20
Identities = 102/381 (26%), Positives = 162/381 (42%), Gaps = 55/381 (14%)
Query: 8 WFLSVAFLLVFIMSLLFTYSHHSMATLPYLDSGALDGTHRVKLVPGYAGLQRLSKERLSG 67
+F + L LLF ++ P +GA D T A Q + +G
Sbjct: 8 FFWLLLLLTAACSGLLFALYFSAVQRYPGPAAGARDTTSFE------AFFQSKASNSWTG 61
Query: 68 KSCACRRCMGDAGASDWFDSHFDG--NIS-PVWTRENMDLPPDVQRWWMMLQPQFKSHNT 124
K ACR + A HF G N+S PV ++ P R P +
Sbjct: 62 KGQACRHLLHLAIQRH---PHFRGLFNLSIPVLLWGDLFTPALWDRLSQHKAPYGWRGLS 118
Query: 125 NEVLEKLFQIVPGENPYRF----RD-PHQCRRCAVVGNSGNLRGSGYGQDVDGHNFIMRM 179
++V+ ++ G + RD P +C RCAVVGN G L GS G ++D H+++ R+
Sbjct: 119 HQVIASTLSLLNGSESAKLFAPPRDTPPKCIRCAVVGNGGILNGSRQGPNIDAHDYVFRL 178
Query: 180 NQAPTVGFEQDVGSRTTHHFMYPESAKN------------LP--ANVSFVLVPFKVLDLL 225
N A GFE+DVG++T+ + + KN +P ++ ++ +P + D +
Sbjct: 179 NGAVIKGFERDVGTKTSFYGFTVNTMKNSLVSYWNLGFTSVPQGQDLQYIFIPSDIRDYV 238
Query: 226 WIASA---------LSTGQIRFTYAPVKSFLRVDKEKVQIYNPAFFKYIHDRWTE----- 271
+ SA L G Y ++ K ++ +P F Y+ +R+ +
Sbjct: 239 MLRSAILGVPVPEGLDKGDRPHAYFGPEA----SASKFKLLHPDFISYLTERFLKSKLIN 294
Query: 272 -HHG--RYPSTGMLVLFFALHVCDEVNVYGFGADSRGNW-HHYWENNRYAGEFRKTGVHD 327
H G PSTG L+L ALH CD+V+ YGF + + HY+E F HD
Sbjct: 295 THFGDLYMPSTGALMLLTALHTCDQVSAYGFITSNYWKFSDHYFERKMKPLIFYAN--HD 352
Query: 328 ADFEAHIIDMLAKASKIEVYR 348
EA + L KA +++Y+
Sbjct: 353 LSLEAALWRDLHKAGILQLYQ 373
>gi|109633046 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
isoform 2 [Homo sapiens]
Length = 395
Score = 92.4 bits (228), Expect = 5e-19
Identities = 78/321 (24%), Positives = 138/321 (42%), Gaps = 43/321 (13%)
Query: 1 MKCSLRVWFLSVAFLLVFIMSLLFTYSHHSMATLPYLDSGALDGTHRVKLVPGYAGLQRL 60
+KC+L V+ +++I+ L +T M + Y+D VK YA Q L
Sbjct: 45 LKCTLLVF----GVWILYILKLNYTTEECDMKKMHYVDPD------HVKRAQKYAQ-QVL 93
Query: 61 SKERLSGKSCACRRCMGDAGASDWFDSHFDGNISPVWTRENMDLPPDVQRWWMMLQPQFK 120
KE CR + F+ + ++ P + D + + P F
Sbjct: 94 QKE--------CRPKFAKTSMALLFEHRYSVDLLPFVQKAPKDSEAESK-----YDPPFG 140
Query: 121 SHNTNEVLEKLFQIVPGENPYRFRDPHQCRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMN 180
+ ++ L +++P + CRRC V+G+ G L G G ++ + ++R+N
Sbjct: 141 FRKFSSKVQTLLELLPEHDLPEHLKAKTCRRCVVIGSGGILHGLELGHTLNQFDVVIRLN 200
Query: 181 QAPTVGFEQDVGSRTTHHFMYPESAK----NLPANVSFVLVPFKVLDLLWIASALSTGQI 236
AP G+ + VG++TT YPE A +N FV V FK +D W+ + + +
Sbjct: 201 SAPVEGYSEHVGNKTTIRMTYPEGAPLSDLEYYSNDLFVAVLFKSVDFNWLQAMVKKETL 260
Query: 237 -----RFTYAPVKSFLRVDKEKVQIYNPAFFK---YIHDRWTEHHGRY-------PSTGM 281
F + V + + + +I NP K + +++E R+ P+ G+
Sbjct: 261 PFWVRLFFWKQVAEKIPLQPKHFRILNPVIIKETAFDILQYSEPQSRFWGRDKNVPTIGV 320
Query: 282 LVLFFALHVCDEVNVYGFGAD 302
+ + A H+CDEV++ GFG D
Sbjct: 321 IAVVLATHLCDEVSLAGFGYD 341
>gi|109633044 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
isoform 1 [Homo sapiens]
Length = 418
Score = 92.4 bits (228), Expect = 5e-19
Identities = 78/321 (24%), Positives = 138/321 (42%), Gaps = 43/321 (13%)
Query: 1 MKCSLRVWFLSVAFLLVFIMSLLFTYSHHSMATLPYLDSGALDGTHRVKLVPGYAGLQRL 60
+KC+L V+ +++I+ L +T M + Y+D VK YA Q L
Sbjct: 68 LKCTLLVF----GVWILYILKLNYTTEECDMKKMHYVDPD------HVKRAQKYAQ-QVL 116
Query: 61 SKERLSGKSCACRRCMGDAGASDWFDSHFDGNISPVWTRENMDLPPDVQRWWMMLQPQFK 120
KE CR + F+ + ++ P + D + + P F
Sbjct: 117 QKE--------CRPKFAKTSMALLFEHRYSVDLLPFVQKAPKDSEAESK-----YDPPFG 163
Query: 121 SHNTNEVLEKLFQIVPGENPYRFRDPHQCRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMN 180
+ ++ L +++P + CRRC V+G+ G L G G ++ + ++R+N
Sbjct: 164 FRKFSSKVQTLLELLPEHDLPEHLKAKTCRRCVVIGSGGILHGLELGHTLNQFDVVIRLN 223
Query: 181 QAPTVGFEQDVGSRTTHHFMYPESAK----NLPANVSFVLVPFKVLDLLWIASALSTGQI 236
AP G+ + VG++TT YPE A +N FV V FK +D W+ + + +
Sbjct: 224 SAPVEGYSEHVGNKTTIRMTYPEGAPLSDLEYYSNDLFVAVLFKSVDFNWLQAMVKKETL 283
Query: 237 -----RFTYAPVKSFLRVDKEKVQIYNPAFFK---YIHDRWTEHHGRY-------PSTGM 281
F + V + + + +I NP K + +++E R+ P+ G+
Sbjct: 284 PFWVRLFFWKQVAEKIPLQPKHFRILNPVIIKETAFDILQYSEPQSRFWGRDKNVPTIGV 343
Query: 282 LVLFFALHVCDEVNVYGFGAD 302
+ + A H+CDEV++ GFG D
Sbjct: 344 IAVVLATHLCDEVSLAGFGYD 364
>gi|5174697 alpha2,3-sialyltransferase VI [Homo sapiens]
Length = 331
Score = 89.0 bits (219), Expect = 6e-18
Identities = 58/201 (28%), Positives = 97/201 (48%), Gaps = 21/201 (10%)
Query: 149 CRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAPTVGFEQDVGSRTTHHFMYPESAKNL 208
C++C VVGN G L+ G+ +D ++ I+RMN P +G E++VG RTT YPES +
Sbjct: 115 CKKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRTTFRLFYPESVFSD 174
Query: 209 P----ANVSFVLVPFKVLDLLWIASALSTGQIR---FTYAPVKSFLRVDKEKVQIYNP-- 259
P N + +L FK DL W+ L +I F P + + +++I +P
Sbjct: 175 PIHNDPNTTVILTAFKPHDLRWLLELLMGDKINTNGFWKKPALNLI-YKPYQIRILDPFI 233
Query: 260 ---AFFKYIHDRWT---EHHGRYPSTGMLVLFFALHVCDEVNVYGFG---ADSRGNWHHY 310
A ++ +H ++P+TG++ + A ++C EV++ GF +D + H+Y
Sbjct: 234 IRTAAYELLHFPKVFPKNQKPKHPTTGIIAITLAFYICHEVHLAGFKYNFSDLKSPLHYY 293
Query: 311 WENNRYAGEFRKTGVHDADFE 331
N K H+ E
Sbjct: 294 --GNATMSLMNKNAYHNVTAE 312
>gi|28373092 sialyltransferase 7D isoform a [Homo sapiens]
Length = 302
Score = 85.1 bits (209), Expect = 8e-17
Identities = 67/203 (33%), Positives = 91/203 (44%), Gaps = 24/203 (11%)
Query: 132 FQIVPGENPYRFRDPHQCRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAPTVGFEQDV 191
+ VP P R+P CR CAVV +SG + GSG G ++D + RMNQAPTVGFE DV
Sbjct: 59 YSSVPDGKPL-VREP--CRSCAVVSSSGQMLGSGLGAEIDSAECVFRMNQAPTVGFEADV 115
Query: 192 GSRTTHHFMYPESAKNLPANVSFVLVPFKVLDLLWIASALSTGQIRF----TYAPVKSFL 247
G R+T + S L N S K D L++ R TY +
Sbjct: 116 GQRSTLRVVSHTSVPLLLRNYSHYFQ--KARDTLYMVWGQGRHMDRVLGGRTYRTLLQLT 173
Query: 248 RV--------DKEKVQIYNPAFFKYIHDRWTEHHGRYPSTGMLVLFFALHVCDEVNVYGF 299
R+ E++ Y F+ + G + STG + AL +C+E+ VYG
Sbjct: 174 RMYPGLQVYTFTERMMAYCDQIFQDETGKNRRQSGSFLSTGWFTMILALELCEEIVVYGM 233
Query: 300 GADS--RGNWH-----HYWENNR 315
+DS R H HY+E R
Sbjct: 234 VSDSYCREKSHPSVPYHYFEKGR 256
>gi|21264332 sialyltransferase 7A [Homo sapiens]
Length = 600
Score = 81.3 bits (199), Expect = 1e-15
Identities = 58/197 (29%), Positives = 99/197 (50%), Gaps = 30/197 (15%)
Query: 148 QCRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAPTVGFEQDVGSRTTHH----FMYPE 203
+C CAVVGN G L S GQ++D H+++ R++ A G+EQDVG+RT+ + F +
Sbjct: 361 RCITCAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSLTQ 420
Query: 204 SA--------KNLP--ANVSFVLVPFKVLDLLWIASAL------STGQIRFTYAPVKSFL 247
S KN+P +V ++ D W+ + L S F + P ++F
Sbjct: 421 SLLILGNRGFKNVPLGKDVRYLHFLEGTRDYEWLEALLMNQTVMSKNLFWFRHRPQEAFR 480
Query: 248 R-VDKEKVQIYNPAFFKYIHDRWTEH------HGRY--PSTGMLVLFFALHVCDEVNVYG 298
+ ++ + +P F +Y+ +R+ H R P+TG L+L AL +CD+V+ YG
Sbjct: 481 EALHMDRYLLLHPDFLRYMKNRFLRSKTLDGAHWRIYRPTTGALLLLTALQLCDQVSAYG 540
Query: 299 FGADSRGNW-HHYWENN 314
F + + HY++ +
Sbjct: 541 FITEGHERFSDHYYDTS 557
>gi|28373074 sialyltransferase 6 isoform d [Homo sapiens]
Length = 277
Score = 78.2 bits (191), Expect = 1e-14
Identities = 42/110 (38%), Positives = 58/110 (52%), Gaps = 6/110 (5%)
Query: 145 DPHQCRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAPTVGFEQDVGSRTTHHFMYPES 204
D +CRRC +VGN G L G +D ++ ++R+N AP GFE+DVGS+TT YPE
Sbjct: 153 DSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEG 212
Query: 205 AKNLPANVS----FVLVPFKVLDLLWIASALSTGQIRFTY--APVKSFLR 248
A P FVL FK D W+ + ++ +T+ K FLR
Sbjct: 213 AMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSWTHNIQREKEFLR 262
>gi|5031999 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 4 isoform a [Homo sapiens]
Length = 359
Score = 77.8 bits (190), Expect = 1e-14
Identities = 65/243 (26%), Positives = 112/243 (46%), Gaps = 22/243 (9%)
Query: 124 TNEVLEKLFQIVPGENPYRFRDPHQCRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAP 183
T + L ++P +P + R + + CAVVGNSG L S G+++D HNF++R N AP
Sbjct: 117 TLNISHDLHSLLPEVSPMKNR---RFKTCAVVGNSGILLDSECGKEIDSHNFVIRCNLAP 173
Query: 184 TVGFEQDVGSRTTHHFMYPE-------SAKNLPANVSFVLVPFKVLD-LLWIASALSTGQ 235
V F DVG+++ M P +N FV + D +LWI + + G
Sbjct: 174 VVEFAADVGTKSDFITMNPSVVQRAFGGFRNESDREKFVHRLSMLNDSVLWIPAFMVKGG 233
Query: 236 IRFTYAPVKSFLRVDKEKVQIYNPA--FFKYIHDRWTEHHG--RYPSTGMLVLFFALHVC 291
+ V + + +K KV+ P+ + W + + PSTG+L+ A C
Sbjct: 234 EKHV-EWVNALILKNKLKVRTAYPSLRLIHAVRGYWLTNKVPIKRPSTGLLMYTLATRFC 292
Query: 292 DEVNVYGF-----GADSRGNWHHYWENNRYAGEFRKTGVHDADFEAHIIDMLAKASKIEV 346
DE+++YGF + + +HY+++ +Y F H E +++L +++
Sbjct: 293 DEIHLYGFWPFPKDLNGKAVKYHYYDDLKYR-YFSNASPHRMPLEFKTLNVLHNRGALKL 351
Query: 347 YRG 349
G
Sbjct: 352 TTG 354
>gi|110815855 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 3 [Homo sapiens]
Length = 380
Score = 73.2 bits (178), Expect = 3e-13
Identities = 52/160 (32%), Positives = 80/160 (50%), Gaps = 12/160 (7%)
Query: 152 CAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAPTVGFEQDVGSRTTHHFMYPESAKNLPAN 211
CAVVGNSG L GS GQ++D +F+ R N APT F++DVG +T P + N
Sbjct: 162 CAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNPSILEKYYNN 221
Query: 212 VSFV------LVPFKVLD--LLWIASALSTGQIRFTYAPVKSFLRVDKE-KVQIYNPA-F 261
+ + + K LD +LWI + T V F+ + KVQ+ P
Sbjct: 222 LLTIQDRNNFFLSLKKLDGAILWIPAFFFHTSATVTRTLVDFFVEHRGQLKVQLAWPGNI 281
Query: 262 FKYIHDRWTEHH--GRYPSTGMLVLFFALHVCDEVNVYGF 299
++++ W H + STG+L+ A +C+E+++YGF
Sbjct: 282 MQHVNRYWKNKHLSPKRLSTGILMYTLASAICEEIHLYGF 321
>gi|5174677 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 2 [Homo sapiens]
Length = 375
Score = 72.8 bits (177), Expect = 4e-13
Identities = 58/229 (25%), Positives = 101/229 (44%), Gaps = 49/229 (21%)
Query: 119 FKSHNTNEVLEKLFQIVPGENPYRFRDPHQCRRCAVVGNSGNLRGSGYGQDVDGHNFIMR 178
F +T V + L++++P +P + + CA+VGNSG L SG GQ++D H+F++R
Sbjct: 127 FDRDSTMNVSQNLYELLPRTSPLKNK---HFGTCAIVGNSGVLLNSGCGQEIDAHSFVIR 183
Query: 179 MNQAPTVGFEQDVGSRTTHHFMYPESAKNLPANVSFVLVPFKVL--------DLLWIASA 230
N AP + +DVG +T M P + ++ K+L +LWI +
Sbjct: 184 CNLAPVQEYARDVGLKTDLVTMNPSVIQRAFEDLVNATWREKLLQRLHSLNGSILWIPAF 243
Query: 231 LSTGQIRFTYAPVKSFLRVDKEKVQIYNPAFFKY----------------IHDRWTEH-- 272
++ G KE+V+ N K+ + W +
Sbjct: 244 MARG---------------GKERVEWVNELILKHHVNVRTAYPSLRLLHAVRGYWLTNKV 288
Query: 273 HGRYPSTGMLVLFFALHVCDEVNVYG---FGADSRGN--WHHYWENNRY 316
H + P+TG+L+ A C ++ +YG F D N +HY+++ +Y
Sbjct: 289 HIKRPTTGLLMYTLATRFCKQIYLYGFWPFPLDQNQNPVKYHYYDSLKY 337
>gi|4506953 alpha-2,8-sialyltransferase 1 [Homo sapiens]
Length = 356
Score = 70.1 bits (170), Expect = 3e-12
Identities = 56/209 (26%), Positives = 93/209 (44%), Gaps = 43/209 (20%)
Query: 132 FQIVPGENPYRFRDPHQCRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAP-TVGFEQD 190
+ + P P++ ++CAVVGN G L+ SG G+ +D NF+MR N P + + +D
Sbjct: 122 YSLFPQATPFQL----PLKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKD 177
Query: 191 VGSRTTHHFMYPESAKNLPANVSFVLVPFKVLDLLW----IASALSTGQIRFTYAPVKSF 246
VGS+ ++ + AN S + F+ +LLW + + Y P S
Sbjct: 178 VGSK----------SQLVTANPSIIRQRFQ--NLLWSRKTFVDNMKIYNHSYIYMPAFSM 225
Query: 247 LRVDKEKVQIY---------------NPAFFKYIHDRWTEH--HGRYPSTGMLVLFFALH 289
+ +++Y NP F + I W H + STG+ ++ AL
Sbjct: 226 KTGTEPSLRVYYTLSDVGANQTVLFANPNFLRSIGKFWKSRGIHAKRLSTGLFLVSAALG 285
Query: 290 VCDEVNVYGF-----GADSRGNWHHYWEN 313
+C+EV +YGF + HHY++N
Sbjct: 286 LCEEVAIYGFWPFSVNMHEQPISHHYYDN 314
>gi|4506949 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
isoform a [Homo sapiens]
Length = 406
Score = 68.9 bits (167), Expect = 6e-12
Identities = 51/210 (24%), Positives = 92/210 (43%), Gaps = 14/210 (6%)
Query: 151 RCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAPTVGFEQDVGSRTTHHFMYPESAKNLPA 210
RCAVV ++G+L+ S G+++D H+ ++R N APT F+QDVG++TT M +
Sbjct: 183 RCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAPTANFQQDVGTKTTIRLMNSQLVTTEKR 242
Query: 211 NVSFVLVPFKVLDLLWIASALSTGQIRFTYAPVKSFLRVDK--EKVQIYNPAFFKYIHDR 268
+ L +L ++W S + ++ P +F K K+ P +
Sbjct: 243 FLKDSLYNEGIL-IVWDPSVYHSDIPKWYQNPDYNFFNNYKTYRKLHPNQPFYILKPQMP 301
Query: 269 W-----------TEHHGRYPSTGMLVLFFALHVCDEVNVYGFGADSRGNWHHYWENNRYA 317
W E PS+GML + + +CD+V++Y F R Y+ +
Sbjct: 302 WELWDILQEISPEEIQPNPPSSGMLGIIIMMTLCDQVDIYEFLPSKRKTDVCYYYQKFFD 361
Query: 318 GEFRKTGVHDADFEAHIIDMLAKASKIEVY 347
H +E +++ L + + ++Y
Sbjct: 362 SACTMGAYHPLLYEKNLVKHLNQGTDEDIY 391
>gi|27765091 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
isoform a [Homo sapiens]
Length = 406
Score = 68.9 bits (167), Expect = 6e-12
Identities = 51/210 (24%), Positives = 92/210 (43%), Gaps = 14/210 (6%)
Query: 151 RCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAPTVGFEQDVGSRTTHHFMYPESAKNLPA 210
RCAVV ++G+L+ S G+++D H+ ++R N APT F+QDVG++TT M +
Sbjct: 183 RCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAPTANFQQDVGTKTTIRLMNSQLVTTEKR 242
Query: 211 NVSFVLVPFKVLDLLWIASALSTGQIRFTYAPVKSFLRVDK--EKVQIYNPAFFKYIHDR 268
+ L +L ++W S + ++ P +F K K+ P +
Sbjct: 243 FLKDSLYNEGIL-IVWDPSVYHSDIPKWYQNPDYNFFNNYKTYRKLHPNQPFYILKPQMP 301
Query: 269 W-----------TEHHGRYPSTGMLVLFFALHVCDEVNVYGFGADSRGNWHHYWENNRYA 317
W E PS+GML + + +CD+V++Y F R Y+ +
Sbjct: 302 WELWDILQEISPEEIQPNPPSSGMLGIIIMMTLCDQVDIYEFLPSKRKTDVCYYYQKFFD 361
Query: 318 GEFRKTGVHDADFEAHIIDMLAKASKIEVY 347
H +E +++ L + + ++Y
Sbjct: 362 SACTMGAYHPLLYEKNLVKHLNQGTDEDIY 391
>gi|28373094 sialyltransferase 7D isoform b [Homo sapiens]
Length = 218
Score = 66.6 bits (161), Expect = 3e-11
Identities = 54/172 (31%), Positives = 74/172 (43%), Gaps = 21/172 (12%)
Query: 163 GSGYGQDVDGHNFIMRMNQAPTVGFEQDVGSRTTHHFMYPESAKNLPANVSFVLVPFKVL 222
GSG G ++D + RMNQAPTVGFE DVG R+T + S L N S K
Sbjct: 3 GSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLLLRNYSHYFQ--KAR 60
Query: 223 DLLWIASALSTGQIRF----TYAPVKSFLRV--------DKEKVQIYNPAFFKYIHDRWT 270
D L++ R TY + R+ E++ Y F+ +
Sbjct: 61 DTLYMVWGQGRHMDRVLGGRTYRTLLQLTRMYPGLQVYTFTERMMAYCDQIFQDETGKNR 120
Query: 271 EHHGRYPSTGMLVLFFALHVCDEVNVYGFGADS--RGNWH-----HYWENNR 315
G + STG + AL +C+E+ VYG +DS R H HY+E R
Sbjct: 121 RQSGSFLSTGWFTMILALELCEEIVVYGMVSDSYCREKSHPSVPYHYFEKGR 172
>gi|229892273 sialyltransferase 7C isoform 1 [Homo sapiens]
Length = 305
Score = 65.1 bits (157), Expect = 9e-11
Identities = 52/184 (28%), Positives = 77/184 (41%), Gaps = 17/184 (9%)
Query: 149 CRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAPTVGFEQDVGS----RTTHHFMYPES 204
C CA+V NSG + G G ++D + I RMN APT G+E+DVG R H P
Sbjct: 77 CDLCAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRMTMIRVVSHTSVPLL 136
Query: 205 AKN-----LPANVSFVLVPFKVLDLLWIASALSTGQIRFTYAPV-KSFLRVDKEKVQIYN 258
KN AN + ++ ++ + + ++ T + + V EK Y
Sbjct: 137 LKNPDYFFKEANTTIYVIWGPFRNMRKDGNGIVYNMLKKTVGIYPNAQIYVTTEKRMSYC 196
Query: 259 PAFFKYIHDRWTEHHGRYPSTGMLVLFFALHVCDEVNVYGFGADS-------RGNWHHYW 311
FK + G Y STG A+ C ++VYG D+ R +HY+
Sbjct: 197 DGVFKKETGKDRVQSGSYLSTGWFTFLLAMDACYGIHVYGMINDTYCKTEGYRKVPYHYY 256
Query: 312 ENNR 315
E R
Sbjct: 257 EQGR 260
>gi|28373101 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 5 [Homo sapiens]
Length = 376
Score = 63.2 bits (152), Expect = 3e-10
Identities = 56/202 (27%), Positives = 97/202 (48%), Gaps = 22/202 (10%)
Query: 129 EKLFQIVPGENPYRFRDPHQCRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAP-TVGF 187
+++F++ P + PY +R Q ++CAVVGN G L+ S G++++ +F+ R N P + +
Sbjct: 144 QEIFRMFPKDMPY-YRS--QFKKCAVVGNGGILKNSRCGREINSADFVFRCNLPPISEKY 200
Query: 188 EQDVGSRTTHHFMYPESAKNLPANVSFVLVPF-KVLDLLWIASALSTGQIRFTYAPVKSF 246
DVG +T + P + PF +VL + AS L V
Sbjct: 201 TMDVGVKTDVVTVNPSIITERFHKLEKWRRPFYRVLQVYENASVLLPAFYNTRNTDVS-- 258
Query: 247 LRVDKEKVQIYNPAFFKYIHDRWTEHHGRY----------PSTGMLVLFFALHVCDEVNV 296
+RV +P Y H ++ + RY STG++++ AL +C+EV++
Sbjct: 259 IRVKYVLDDFESPQAVYYFHPQYLVNVSRYWLSLGVRAKRISTGLILVTAALELCEEVHL 318
Query: 297 YGFGA---DSRGNW--HHYWEN 313
+GF A + G + HHY++N
Sbjct: 319 FGFWAFPMNPSGLYITHHYYDN 340
>gi|215272345 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
isoform a [Homo sapiens]
Length = 529
Score = 61.6 bits (148), Expect = 1e-09
Identities = 51/221 (23%), Positives = 93/221 (42%), Gaps = 23/221 (10%)
Query: 146 PHQCRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAPTVGFEQDVGSRTT--------- 196
P R CAVV ++G + S G+++D H+ ++R N APT G+E+DVG++TT
Sbjct: 290 PRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQIL 349
Query: 197 ----HHFMYPESAKNLPANVSFVLVPFKVLDLLWIASALSTGQIRFTYAPVKSFLRVDKE 252
HHF+ K++ V++ P+ LW ++ R +
Sbjct: 350 TNPSHHFIDSSLYKDV-ILVAWDPAPYSANLNLWYKKP----DYNLFTPYIQHRQRNPNQ 404
Query: 253 KVQIYNPAFFKYIHDRWTEH-----HGRYPSTGMLVLFFALHVCDEVNVYGFGADSRGNW 307
I +P F + D E+ PS+G + + + +C EV+VY + R
Sbjct: 405 PFYILHPKFIWQLWDIIQENTKEKIQPNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTE 464
Query: 308 HHYWENNRYAGEFRKTGVHDADFEAHIIDMLAKASKIEVYR 348
++ Y H +E ++ L ++ +++R
Sbjct: 465 LCHYHELYYDAACTLGAYHPLLYEKLLVQRLNMGTQGDLHR 505
>gi|26190610 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
isoform a [Homo sapiens]
Length = 529
Score = 61.6 bits (148), Expect = 1e-09
Identities = 51/221 (23%), Positives = 93/221 (42%), Gaps = 23/221 (10%)
Query: 146 PHQCRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAPTVGFEQDVGSRTT--------- 196
P R CAVV ++G + S G+++D H+ ++R N APT G+E+DVG++TT
Sbjct: 290 PRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQIL 349
Query: 197 ----HHFMYPESAKNLPANVSFVLVPFKVLDLLWIASALSTGQIRFTYAPVKSFLRVDKE 252
HHF+ K++ V++ P+ LW ++ R +
Sbjct: 350 TNPSHHFIDSSLYKDV-ILVAWDPAPYSANLNLWYKKP----DYNLFTPYIQHRQRNPNQ 404
Query: 253 KVQIYNPAFFKYIHDRWTEH-----HGRYPSTGMLVLFFALHVCDEVNVYGFGADSRGNW 307
I +P F + D E+ PS+G + + + +C EV+VY + R
Sbjct: 405 PFYILHPKFIWQLWDIIQENTKEKIQPNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTE 464
Query: 308 HHYWENNRYAGEFRKTGVHDADFEAHIIDMLAKASKIEVYR 348
++ Y H +E ++ L ++ +++R
Sbjct: 465 LCHYHELYYDAACTLGAYHPLLYEKLLVQRLNMGTQGDLHR 505
>gi|13569938 sialyltransferase 7E [Homo sapiens]
Length = 336
Score = 60.8 bits (146), Expect = 2e-09
Identities = 47/162 (29%), Positives = 76/162 (46%), Gaps = 14/162 (8%)
Query: 149 CRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAPTVGFEQDVGSRTTHHFMYPESAKNL 208
CR CA+V +SG+L S G +D ++RMN APT G+ +DVG+RT+ + S + +
Sbjct: 93 CRDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRVIAHSSIQRI 152
Query: 209 PANVSFVL-VPFKVLDLLWIASAL----STGQI-------RFTYAPVKSFLRVDKEKVQI 256
N +L V + + W S+ GQ+ +K+F+ + +Q
Sbjct: 153 LRNRHDLLNVSQGTVFIFWGPSSYMRRDGKGQVYNNLHLLSQVLPRLKAFMITRHKMLQF 212
Query: 257 YNPAFFKYIHDRWTEHHGRYPSTGMLVLFFALHVCDEVNVYG 298
FK + + + STG + AL +CD +NVYG
Sbjct: 213 --DELFKQETGKDRKISNTWLSTGWFTMTIALELCDRINVYG 252
>gi|21361444 sialytransferase 7F [Homo sapiens]
Length = 333
Score = 59.7 bits (143), Expect = 4e-09
Identities = 41/162 (25%), Positives = 73/162 (45%), Gaps = 9/162 (5%)
Query: 146 PHQCRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAPTVGFEQDVGSRTTHHFMYPESA 205
P +C +C +V +S +L G+ G +++ +RMN APT G+ DVG++TT+ + S
Sbjct: 102 PSRCHQCVIVSSSSHLLGTKLGPEIERAECTIRMNDAPTTGYSADVGNKTTYRVVAHSSV 161
Query: 206 -KNLPANVSFVLVPFKVLDLLW-IASALSTGQIRFTYAPVKSFLRVDKEKVQIYNPAFFK 263
+ L FV + + + W S + Q ++ L + +P +
Sbjct: 162 FRVLRRPQEFVNRTPETVFIFWGPPSKMQKPQGSLVRVIQRAGLVFPNMEAYAVSPGRMR 221
Query: 264 YIHDRWTEHHGR-------YPSTGMLVLFFALHVCDEVNVYG 298
D + G+ + STG + A+ +CD V+VYG
Sbjct: 222 QFDDLFRGETGKDREKSHSWLSTGWFTMVIAVELCDHVHVYG 263
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.138 0.453
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,026,286
Number of Sequences: 37866
Number of extensions: 643757
Number of successful extensions: 1621
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 36
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1552
Number of HSP's gapped (non-prelim): 42
length of query: 350
length of database: 18,247,518
effective HSP length: 103
effective length of query: 247
effective length of database: 14,347,320
effective search space: 3543788040
effective search space used: 3543788040
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.