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Search of human proteins with 5902002
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5902002 dual specificity phosphatase 14 [Homo sapiens]
(198 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5902002 dual specificity phosphatase 14 [Homo sapiens] 409 e-115
gi|51093845 dual specificity phosphatase 18 [Homo sapiens] 201 3e-52
gi|225703077 dual specificity phosphatase 21 [Homo sapiens] 186 1e-47
gi|4758204 dual specificity phosphatase 1 [Homo sapiens] 114 7e-26
gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens] 111 4e-25
gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens] 111 4e-25
gi|4758206 dual specificity phosphatase 2 [Homo sapiens] 107 5e-24
gi|38372911 dual specificity phosphatase 16 [Homo sapiens] 103 1e-22
gi|62865890 dual specificity phosphatase 5 [Homo sapiens] 97 1e-20
gi|75750526 dual specificity phosphatase 28 [Homo sapiens] 96 3e-20
gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens] 95 3e-20
gi|13128968 dual specificity phosphatase 26 [Homo sapiens] 94 1e-19
gi|239047414 slingshot 1 isoform 1 [Homo sapiens] 92 2e-19
gi|239047498 slingshot 1 isoform 3 [Homo sapiens] 92 2e-19
gi|239047441 slingshot 1 isoform 2 [Homo sapiens] 92 2e-19
gi|37674210 slingshot 2 [Homo sapiens] 91 5e-19
gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens] 90 1e-18
gi|238231453 dual specificity phosphatase 7 [Homo sapiens] 89 2e-18
gi|4503421 dual specificity phosphatase 9 [Homo sapiens] 89 2e-18
gi|56117818 muscle-restricted dual specificity phosphatase isofo... 87 7e-18
gi|21536333 dual specificity phosphatase 10 isoform b [Homo sapi... 87 7e-18
gi|21536331 dual specificity phosphatase 10 isoform b [Homo sapi... 87 7e-18
gi|153281158 dual specificity phosphatase 8 [Homo sapiens] 86 2e-17
gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo sapi... 81 5e-16
gi|29826315 dual specificity phosphatase 15 isoform a [Homo sapi... 79 3e-15
gi|56237018 testis and skeletal muscle-specific dual specificity... 77 1e-14
gi|56117822 testis and skeletal muscle-specific dual specificity... 77 1e-14
gi|56117820 testis and skeletal muscle-specific dual specificity... 77 1e-14
gi|122937243 dual specificity phosphatase 27 [Homo sapiens] 76 2e-14
gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo ... 76 2e-14
>gi|5902002 dual specificity phosphatase 14 [Homo sapiens]
Length = 198
Score = 409 bits (1052), Expect = e-115
Identities = 198/198 (100%), Positives = 198/198 (100%)
Query: 1 MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNAT 60
MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNAT
Sbjct: 1 MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNAT 60
Query: 61 IEIPNFNWPQFEYVKVPLADMPHAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSAT 120
IEIPNFNWPQFEYVKVPLADMPHAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSAT
Sbjct: 61 IEIPNFNWPQFEYVKVPLADMPHAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSAT 120
Query: 121 LCIAYLMKFHNVCLLEAYNWVKARRPVIRPNVGFWRQLIDYERQLFGKSTVKMVQTPYGI 180
LCIAYLMKFHNVCLLEAYNWVKARRPVIRPNVGFWRQLIDYERQLFGKSTVKMVQTPYGI
Sbjct: 121 LCIAYLMKFHNVCLLEAYNWVKARRPVIRPNVGFWRQLIDYERQLFGKSTVKMVQTPYGI 180
Query: 181 VPDVYEKESRHLMPYWGI 198
VPDVYEKESRHLMPYWGI
Sbjct: 181 VPDVYEKESRHLMPYWGI 198
>gi|51093845 dual specificity phosphatase 18 [Homo sapiens]
Length = 188
Score = 201 bits (511), Expect = 3e-52
Identities = 90/179 (50%), Positives = 130/179 (72%)
Query: 16 PRMISEGDIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNFNWPQFEYVK 75
P + + G++QIT SL++ G A+N+ +L + IT ++N ++E+ N + +Y++
Sbjct: 9 PVQFRQPSVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTLYEDIQYMQ 68
Query: 76 VPLADMPHAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLL 135
VP+AD P++ + +FD +AD IHSV K G TL+HCAAGVSRSA LC+AYLMK+H + LL
Sbjct: 69 VPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLL 128
Query: 136 EAYNWVKARRPVIRPNVGFWRQLIDYERQLFGKSTVKMVQTPYGIVPDVYEKESRHLMP 194
+A+ W K+ RP+IRPN GFW QLI YE QLFGK+TV MV +P G++PD+YEKE R ++P
Sbjct: 129 DAHTWTKSCRPIIRPNSGFWEQLIHYEFQLFGKNTVHMVSSPVGMIPDIYEKEVRLMIP 187
>gi|225703077 dual specificity phosphatase 21 [Homo sapiens]
Length = 190
Score = 186 bits (472), Expect = 1e-47
Identities = 84/175 (48%), Positives = 126/175 (72%)
Query: 19 ISEGDIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNFNWPQFEYVKVPL 78
+ + I +QIT SLFL G A+++ LL + IT IVNA++E+ N + +Y+KVP+
Sbjct: 14 VQQPSIYSFSQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFEGIQYIKVPV 73
Query: 79 ADMPHAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAY 138
D + + +FD +AD IH++ + G TL+HC AGVSRSA+LC+AYLMK+H++ LL+A+
Sbjct: 74 TDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAH 133
Query: 139 NWVKARRPVIRPNVGFWRQLIDYERQLFGKSTVKMVQTPYGIVPDVYEKESRHLM 193
W K+RRP+IRPN GFW QLI+YE +LF +TV+M+ +P G +PD+YEK+ R ++
Sbjct: 134 TWTKSRRPIIRPNNGFWEQLINYEFKLFNNNTVRMINSPVGNIPDIYEKDLRMMI 188
>gi|4758204 dual specificity phosphatase 1 [Homo sapiens]
Length = 367
Score = 114 bits (284), Expect = 7e-26
Identities = 58/143 (40%), Positives = 83/143 (58%)
Query: 23 DIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNFNWPQFEYVKVPLADMP 82
D GG +I L+LG AS + +L A GIT ++N + PN ++Y +P+ D
Sbjct: 170 DQGGPVEILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNH 229
Query: 83 HAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVK 142
A I +F+ D I S+ G VHC AG+SRSAT+C+AYLM+ + V L EA+ +VK
Sbjct: 230 KADISSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVK 289
Query: 143 ARRPVIRPNVGFWRQLIDYERQL 165
RR +I PN F QL+ +E Q+
Sbjct: 290 QRRSIISPNFSFMGQLLQFESQV 312
>gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens]
Length = 394
Score = 111 bits (278), Expect = 4e-25
Identities = 61/157 (38%), Positives = 86/157 (54%)
Query: 23 DIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNFNWPQFEYVKVPLADMP 82
D GG +I L+LG A+ R +L A GIT ++N + + PN ++Y +P+ D
Sbjct: 192 DQGGPVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVEDNH 251
Query: 83 HAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVK 142
A I +F + I +V G LVHC AG+SRSAT+C+AYLM V L EA+ +VK
Sbjct: 252 KADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVK 311
Query: 143 ARRPVIRPNVGFWRQLIDYERQLFGKSTVKMVQTPYG 179
RR +I PN F QL+ +E Q+ S +P G
Sbjct: 312 QRRSIISPNFSFMGQLLQFESQVLATSCAAEAASPSG 348
>gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens]
Length = 303
Score = 111 bits (278), Expect = 4e-25
Identities = 61/157 (38%), Positives = 86/157 (54%)
Query: 23 DIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNFNWPQFEYVKVPLADMP 82
D GG +I L+LG A+ R +L A GIT ++N + + PN ++Y +P+ D
Sbjct: 101 DQGGPVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVEDNH 160
Query: 83 HAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVK 142
A I +F + I +V G LVHC AG+SRSAT+C+AYLM V L EA+ +VK
Sbjct: 161 KADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVK 220
Query: 143 ARRPVIRPNVGFWRQLIDYERQLFGKSTVKMVQTPYG 179
RR +I PN F QL+ +E Q+ S +P G
Sbjct: 221 QRRSIISPNFSFMGQLLQFESQVLATSCAAEAASPSG 257
>gi|4758206 dual specificity phosphatase 2 [Homo sapiens]
Length = 314
Score = 107 bits (268), Expect = 5e-24
Identities = 61/143 (42%), Positives = 80/143 (55%)
Query: 23 DIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNFNWPQFEYVKVPLADMP 82
D GG +I LFLG S +S+ LQA GIT ++N + PN F Y +P+ D
Sbjct: 169 DQGGPVEILPYLFLGSCSHSSDLQGLQACGITAVLNVSASCPNHFEGLFRYKSIPVEDNQ 228
Query: 83 HAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVK 142
I +F I V G LVHC AG+SRSAT+C+AYLM+ V L EA+++VK
Sbjct: 229 MVEISAWFQEAIGFIDWVKNSGGRVLVHCQAGISRSATICLAYLMQSRRVRLDEAFDFVK 288
Query: 143 ARRPVIRPNVGFWRQLIDYERQL 165
RR VI PN F QL+ +E Q+
Sbjct: 289 QRRGVISPNFSFMGQLLQFETQV 311
>gi|38372911 dual specificity phosphatase 16 [Homo sapiens]
Length = 665
Score = 103 bits (257), Expect = 1e-22
Identities = 61/162 (37%), Positives = 93/162 (57%), Gaps = 2/162 (1%)
Query: 5 GHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNATIEIP 64
G STL T ++ + +IG +I +L+LG N+ L+Q GI ++NA+ P
Sbjct: 138 GKSTLVPTCISQPCLPVANIGP-TRILPNLYLGCQRDVLNKELMQQNGIGYVLNASNTCP 196
Query: 65 NFNW-PQFEYVKVPLADMPHAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCI 123
++ P+ +++VP+ D I + D D I +G LVHC AG+SRSAT+ I
Sbjct: 197 KPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAI 256
Query: 124 AYLMKFHNVCLLEAYNWVKARRPVIRPNVGFWRQLIDYERQL 165
AY+MK ++ L EAY +VK +RP I PN F QL+DYE+++
Sbjct: 257 AYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDYEKKI 298
>gi|62865890 dual specificity phosphatase 5 [Homo sapiens]
Length = 384
Score = 96.7 bits (239), Expect = 1e-20
Identities = 54/143 (37%), Positives = 74/143 (51%)
Query: 23 DIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNFNWPQFEYVKVPLADMP 82
D GG +I L+LG AS L IT ++N + Y +P+ D
Sbjct: 175 DQGGPVEILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACATHLHYKWIPVEDSH 234
Query: 83 HAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVK 142
A I +F D I V K G LVHC AG+SRS T+C+AYLMK L EA++++K
Sbjct: 235 TADISSHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIK 294
Query: 143 ARRPVIRPNVGFWRQLIDYERQL 165
RR ++ PN GF QL+ YE ++
Sbjct: 295 QRRSMVSPNFGFMGQLLQYESEI 317
>gi|75750526 dual specificity phosphatase 28 [Homo sapiens]
Length = 176
Score = 95.5 bits (236), Expect = 3e-20
Identities = 53/157 (33%), Positives = 79/157 (50%)
Query: 27 IAQITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNFNWPQFEYVKVPLADMPHAPI 86
+ ++ SLFLG A L G+T VN + + P P ++VP+ D P +
Sbjct: 19 LVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPRAPGVAELRVPVFDDPAEDL 78
Query: 87 GLYFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRP 146
+ + + + R GA LV+C G SRSA +C AYLM+ + L +A+ VK+ RP
Sbjct: 79 LAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSLAKAFQMVKSARP 138
Query: 147 VIRPNVGFWRQLIDYERQLFGKSTVKMVQTPYGIVPD 183
V PN GFW QL YE L +S ++ G+ P+
Sbjct: 139 VAEPNPGFWSQLQKYEEALQAQSCLQGEPPALGLGPE 175
>gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]
Length = 482
Score = 95.1 bits (235), Expect = 3e-20
Identities = 54/166 (32%), Positives = 86/166 (51%), Gaps = 5/166 (3%)
Query: 2 SSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNATI 61
+S S LP+ + I ++ I LFLG A + +Q I ++N T
Sbjct: 300 ASAASSLLPQPIPTTPDIENAEL---TPILPFLFLGNEQDAQDLDTMQRLNIGYVINVTT 356
Query: 62 EIPNFNWPQ--FEYVKVPLADMPHAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSA 119
+P +++ + F Y ++P D + YF+ + I + L+HC AGVSRSA
Sbjct: 357 HLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSA 416
Query: 120 TLCIAYLMKFHNVCLLEAYNWVKARRPVIRPNVGFWRQLIDYERQL 165
T+ IAYLMK + + +AY +VK +RP+I PN+ F QL+++E L
Sbjct: 417 TIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDL 462
>gi|13128968 dual specificity phosphatase 26 [Homo sapiens]
Length = 211
Score = 93.6 bits (231), Expect = 1e-19
Identities = 59/143 (41%), Positives = 85/143 (59%), Gaps = 7/143 (4%)
Query: 29 QITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNFNWPQFE-----YVKVPLADMPH 83
++ L+LG +A+NR L+ GIT ++NA+ +E Y+ V D P
Sbjct: 64 EVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHDSPA 123
Query: 84 APIGLYFDTVADKIH-SVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVK 142
+ ++F T AD IH ++S+ G LVHCA GVSRSATL +AYLM +H++ L+EA VK
Sbjct: 124 FDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKVK 183
Query: 143 ARRPVIRPNVGFWRQLIDYERQL 165
R +I PN GF RQL+ +R+L
Sbjct: 184 DHRGII-PNRGFLRQLLALDRRL 205
>gi|239047414 slingshot 1 isoform 1 [Homo sapiens]
Length = 1049
Score = 92.4 bits (228), Expect = 2e-19
Identities = 55/133 (41%), Positives = 71/133 (53%)
Query: 30 ITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNFNWPQFEYVKVPLADMPHAPIGLY 89
I L+LG ASN LQ G+ I+N T EI NF F Y + + D + +
Sbjct: 312 IFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDLLAH 371
Query: 90 FDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRPVIR 149
++ I+ R H LVHC GVSRSA+ IAY MK L +AYN+VK +R + R
Sbjct: 372 WNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITR 431
Query: 150 PNVGFWRQLIDYE 162
PN GF RQL +YE
Sbjct: 432 PNAGFMRQLSEYE 444
>gi|239047498 slingshot 1 isoform 3 [Homo sapiens]
Length = 703
Score = 92.4 bits (228), Expect = 2e-19
Identities = 55/133 (41%), Positives = 71/133 (53%)
Query: 30 ITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNFNWPQFEYVKVPLADMPHAPIGLY 89
I L+LG ASN LQ G+ I+N T EI NF F Y + + D + +
Sbjct: 323 IFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDLLAH 382
Query: 90 FDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRPVIR 149
++ I+ R H LVHC GVSRSA+ IAY MK L +AYN+VK +R + R
Sbjct: 383 WNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITR 442
Query: 150 PNVGFWRQLIDYE 162
PN GF RQL +YE
Sbjct: 443 PNAGFMRQLSEYE 455
>gi|239047441 slingshot 1 isoform 2 [Homo sapiens]
Length = 692
Score = 92.4 bits (228), Expect = 2e-19
Identities = 55/133 (41%), Positives = 71/133 (53%)
Query: 30 ITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNFNWPQFEYVKVPLADMPHAPIGLY 89
I L+LG ASN LQ G+ I+N T EI NF F Y + + D + +
Sbjct: 312 IFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDLLAH 371
Query: 90 FDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRPVIR 149
++ I+ R H LVHC GVSRSA+ IAY MK L +AYN+VK +R + R
Sbjct: 372 WNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITR 431
Query: 150 PNVGFWRQLIDYE 162
PN GF RQL +YE
Sbjct: 432 PNAGFMRQLSEYE 444
>gi|37674210 slingshot 2 [Homo sapiens]
Length = 1423
Score = 91.3 bits (225), Expect = 5e-19
Identities = 60/142 (42%), Positives = 79/142 (55%), Gaps = 2/142 (1%)
Query: 22 GDIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNFNWPQFEYVKVPLADM 81
G + QI +FLG ASN LQ RG+ I+N T EI NF FEY + + D
Sbjct: 303 GQMDSPTQIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFPGVFEYHNIRVYDE 362
Query: 82 PHAPIGLYFDTVADKIHSVSRKHGAT-LVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNW 140
+ Y++ K S ++KHG+ LVHC GVSRSA+ IAY MK + L AY++
Sbjct: 363 EATDLLAYWNDTY-KFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDY 421
Query: 141 VKARRPVIRPNVGFWRQLIDYE 162
VK RR V +PN F RQL +Y+
Sbjct: 422 VKERRTVTKPNPSFMRQLEEYQ 443
>gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens]
Length = 381
Score = 90.1 bits (222), Expect = 1e-18
Identities = 50/139 (35%), Positives = 79/139 (56%), Gaps = 2/139 (1%)
Query: 29 QITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNF--NWPQFEYVKVPLADMPHAPI 86
+I L+LG ++N +L+ GI I+N T +PN N +F+Y ++P++D +
Sbjct: 209 EILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNL 268
Query: 87 GLYFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRP 146
+F I K+ LVHC AG+SRS T+ +AYLM+ N+ + +AY+ VK ++
Sbjct: 269 SQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKS 328
Query: 147 VIRPNVGFWRQLIDYERQL 165
I PN F QL+D+ER L
Sbjct: 329 NISPNFNFMGQLLDFERTL 347
>gi|238231453 dual specificity phosphatase 7 [Homo sapiens]
Length = 419
Score = 89.4 bits (220), Expect = 2e-18
Identities = 51/139 (36%), Positives = 77/139 (55%), Gaps = 2/139 (1%)
Query: 29 QITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNF--NWPQFEYVKVPLADMPHAPI 86
QI L+LG ++N +L GI I+N T +PN + +F Y ++P++D +
Sbjct: 247 QILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISDHWSQNL 306
Query: 87 GLYFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRP 146
+F I K LVHC AG+SRS T+ +AYLM+ N+ L +AY++VK ++
Sbjct: 307 SQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRKKS 366
Query: 147 VIRPNVGFWRQLIDYERQL 165
I PN F QL+D+ER L
Sbjct: 367 NISPNFNFMGQLLDFERTL 385
>gi|4503421 dual specificity phosphatase 9 [Homo sapiens]
Length = 384
Score = 89.0 bits (219), Expect = 2e-18
Identities = 51/139 (36%), Positives = 77/139 (55%), Gaps = 2/139 (1%)
Query: 29 QITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNF--NWPQFEYVKVPLADMPHAPI 86
QI +L+LG ++N L GI I+N T +PNF F Y ++P++D +
Sbjct: 206 QILPNLYLGSARDSANLESLAKLGIRYILNVTPNLPNFFEKNGDFHYKQIPISDHWSQNL 265
Query: 87 GLYFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRP 146
+F + I ++ LVHC AGVSRS T+ +AYLM+ ++ L +AY+ VK ++
Sbjct: 266 SRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRKKS 325
Query: 147 VIRPNVGFWRQLIDYERQL 165
I PN F QL+D+ER L
Sbjct: 326 NISPNFNFMGQLLDFERSL 344
>gi|56117818 muscle-restricted dual specificity phosphatase isoform
1 [Homo sapiens]
Length = 188
Score = 87.4 bits (215), Expect = 7e-18
Identities = 58/148 (39%), Positives = 78/148 (52%), Gaps = 8/148 (5%)
Query: 27 IAQITSSLFLGRGSVASNRHLLQARGITCIVNATIEI------PNFNWPQFEYVKVPLAD 80
+ ++ +LF+G + A+NR L GIT ++NA + P+F Y+ VP D
Sbjct: 38 VDEVWPNLFIGDAATANNRFELWKLGITHVLNAAHKGLYCQGGPDFYGSSVSYLGVPAHD 97
Query: 81 MPHAPIGLYFDTVADKIHSVSRKHGA-TLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYN 139
+P I YF + AD IH GA LVHC GVSRSATL +AYLM + L +A
Sbjct: 98 LPDFDISAYFSSAADFIHRALNTPGAKVLVHCVVGVSRSATLVLAYLMLHQRLSLRQAVI 157
Query: 140 WVKARRPVIRPNVGFWRQLIDYERQLFG 167
V+ R V PN GF QL ++QL G
Sbjct: 158 TVRQHRWVF-PNRGFLHQLCRLDQQLRG 184
>gi|21536333 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 87.4 bits (215), Expect = 7e-18
Identities = 43/120 (35%), Positives = 69/120 (57%), Gaps = 2/120 (1%)
Query: 48 LQARGITCIVNATIEIPNFNWPQ--FEYVKVPLADMPHAPIGLYFDTVADKIHSVSRKHG 105
+Q I ++N T +P +++ + F Y ++P D + YF+ + I +
Sbjct: 1 MQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGK 60
Query: 106 ATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRPVIRPNVGFWRQLIDYERQL 165
L+HC AGVSRSAT+ IAYLMK + + +AY +VK +RP+I PN+ F QL+++E L
Sbjct: 61 GLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDL 120
>gi|21536331 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 87.4 bits (215), Expect = 7e-18
Identities = 43/120 (35%), Positives = 69/120 (57%), Gaps = 2/120 (1%)
Query: 48 LQARGITCIVNATIEIPNFNWPQ--FEYVKVPLADMPHAPIGLYFDTVADKIHSVSRKHG 105
+Q I ++N T +P +++ + F Y ++P D + YF+ + I +
Sbjct: 1 MQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGK 60
Query: 106 ATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRPVIRPNVGFWRQLIDYERQL 165
L+HC AGVSRSAT+ IAYLMK + + +AY +VK +RP+I PN+ F QL+++E L
Sbjct: 61 GLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDL 120
>gi|153281158 dual specificity phosphatase 8 [Homo sapiens]
Length = 625
Score = 85.9 bits (211), Expect = 2e-17
Identities = 51/144 (35%), Positives = 76/144 (52%), Gaps = 7/144 (4%)
Query: 26 GIAQITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNFNWPQF----EYVKVPLADM 81
G+ +I L+LG N+ L+ GI+ ++NA+ P P F +++VP+ D
Sbjct: 160 GLTRILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPK---PDFICESRFMRVPINDN 216
Query: 82 PHAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWV 141
+ + D + I +VHC AG+SRSAT+ IAY+MK + +AY +V
Sbjct: 217 YCEKLLPWLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFV 276
Query: 142 KARRPVIRPNVGFWRQLIDYERQL 165
K RRP I PN F QL++YER L
Sbjct: 277 KDRRPSISPNFNFLGQLLEYERSL 300
>gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo
sapiens]
Length = 217
Score = 81.3 bits (199), Expect = 5e-16
Identities = 46/129 (35%), Positives = 61/129 (47%)
Query: 34 LFLGRGSVASNRHLLQARGITCIVNATIEIPNFNWPQFEYVKVPLADMPHAPIGLYFDTV 93
L LG A + L+ +T I+N + N F Y + + D+P I YF
Sbjct: 73 LLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSISILDLPETNILSYFPEC 132
Query: 94 ADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRPVIRPNVG 153
+ I RK G LVHC AGVSR+A + I +LM A++ VK RP I PN G
Sbjct: 133 FEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPSICPNSG 192
Query: 154 FWRQLIDYE 162
F QL Y+
Sbjct: 193 FMEQLRTYQ 201
>gi|29826315 dual specificity phosphatase 15 isoform a [Homo
sapiens]
Length = 235
Score = 78.6 bits (192), Expect = 3e-15
Identities = 52/169 (30%), Positives = 82/169 (48%), Gaps = 2/169 (1%)
Query: 26 GIAQITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNFNWPQFEYVKVPLADMPHAP 85
G+ ++ L+LG A + L IT I++ E P Y+++P+AD P P
Sbjct: 4 GMTKVLPGLYLGNFIDAKDLDQLGRNKITHIISIH-ESPQPLLQDITYLRIPVADTPEVP 62
Query: 86 IGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVKARR 145
I +F + IH G LVHC AG+SRS T+ AY+M + + +KA R
Sbjct: 63 IKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKATR 122
Query: 146 PVIRPNVGFWRQLIDYERQLFGKSTVKMVQTPYGIVPDVYEKESRHLMP 194
P+ PN GF +QL ++ + + ++ +G P E+E R L+P
Sbjct: 123 PIANPNPGFRQQLEEF-GWASSQKLRRQLEERFGESPFRDEEELRALLP 170
>gi|56237018 testis and skeletal muscle-specific dual specificity
phosphatase isoform 6 [Homo sapiens]
Length = 198
Score = 77.0 bits (188), Expect = 1e-14
Identities = 58/152 (38%), Positives = 80/152 (52%), Gaps = 10/152 (6%)
Query: 27 IAQITSSLFLGRGSVASNRHLLQARGITCIVNAT---IEIPN----FNWPQFEYVKVPLA 79
I ++ SLFLG A ++ L GIT +VNA ++ + EY +
Sbjct: 46 IDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEAD 105
Query: 80 DMPHAPIGLYFDTVADKIHS-VSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAY 138
D P + +YF VA I + +S G LVHCA GVSRSATL +A+LM N+ L+EA
Sbjct: 106 DNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAI 165
Query: 139 NWVKARRPVIRPNVGFWRQLIDYERQLFGKST 170
V+A R + PN GF RQL + +L G+ T
Sbjct: 166 QTVQAHRNIC-PNSGFLRQLQVLDNRL-GRET 195
>gi|56117822 testis and skeletal muscle-specific dual specificity
phosphatase isoform 3 [Homo sapiens]
Length = 291
Score = 77.0 bits (188), Expect = 1e-14
Identities = 58/152 (38%), Positives = 80/152 (52%), Gaps = 10/152 (6%)
Query: 27 IAQITSSLFLGRGSVASNRHLLQARGITCIVNAT---IEIPN----FNWPQFEYVKVPLA 79
I ++ SLFLG A ++ L GIT +VNA ++ + EY +
Sbjct: 139 IDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEAD 198
Query: 80 DMPHAPIGLYFDTVADKIHS-VSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAY 138
D P + +YF VA I + +S G LVHCA GVSRSATL +A+LM N+ L+EA
Sbjct: 199 DNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAI 258
Query: 139 NWVKARRPVIRPNVGFWRQLIDYERQLFGKST 170
V+A R + PN GF RQL + +L G+ T
Sbjct: 259 QTVQAHRNIC-PNSGFLRQLQVLDNRL-GRET 288
>gi|56117820 testis and skeletal muscle-specific dual specificity
phosphatase isoform 2 [Homo sapiens]
Length = 248
Score = 77.0 bits (188), Expect = 1e-14
Identities = 58/152 (38%), Positives = 80/152 (52%), Gaps = 10/152 (6%)
Query: 27 IAQITSSLFLGRGSVASNRHLLQARGITCIVNAT---IEIPN----FNWPQFEYVKVPLA 79
I ++ SLFLG A ++ L GIT +VNA ++ + EY +
Sbjct: 96 IDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEAD 155
Query: 80 DMPHAPIGLYFDTVADKIHS-VSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAY 138
D P + +YF VA I + +S G LVHCA GVSRSATL +A+LM N+ L+EA
Sbjct: 156 DNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAI 215
Query: 139 NWVKARRPVIRPNVGFWRQLIDYERQLFGKST 170
V+A R + PN GF RQL + +L G+ T
Sbjct: 216 QTVQAHRNIC-PNSGFLRQLQVLDNRL-GRET 245
>gi|122937243 dual specificity phosphatase 27 [Homo sapiens]
Length = 1158
Score = 76.3 bits (186), Expect = 2e-14
Identities = 54/164 (32%), Positives = 84/164 (51%), Gaps = 10/164 (6%)
Query: 9 LPRTLMAPRMISEGDIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNFNW 68
L R L+ R E + ++ ++F+ SVA N+ L+ GIT I+NA +
Sbjct: 118 LQRALVQDRQ--EAPWNEVDEVWPNVFIAEKSVAVNKGRLKRLGITHILNAAHGTGVYTG 175
Query: 69 PQF------EYVKVPLADMPHAPIGLYFDTVADKI-HSVSRKHGATLVHCAAGVSRSATL 121
P+F +Y+ V + D P I +F ++ + ++ G LV G+SRSA L
Sbjct: 176 PEFYTGLEIQYLGVEVDDFPEVDISQHFRKASEFLDEALLTYRGKVLVSSEMGISRSAVL 235
Query: 122 CIAYLMKFHNVCLLEAYNWVKARRPVIRPNVGFWRQLIDYERQL 165
+AYLM FHN+ +LEA V+ +R I PN GF +QL + +L
Sbjct: 236 VVAYLMIFHNMAILEALMTVRKKR-AIYPNEGFLKQLRELNEKL 278
>gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo
sapiens]
Length = 223
Score = 76.3 bits (186), Expect = 2e-14
Identities = 57/154 (37%), Positives = 77/154 (50%), Gaps = 9/154 (5%)
Query: 29 QITSSLFLGRGSVASNRHL--LQARGIT---CI---VNATIEIPNFNWPQFEYVKVPLAD 80
+I LFLG S A L LQ GIT CI + A PNF F Y+ + +AD
Sbjct: 31 EILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQ-QLFRYLVLDIAD 89
Query: 81 MPHAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNW 140
P I +F + I + G LVH AG+SRSA IAY+M+ + +A+ +
Sbjct: 90 NPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAY 149
Query: 141 VKARRPVIRPNVGFWRQLIDYERQLFGKSTVKMV 174
V+ RR I PN GF QL +YE K T++M+
Sbjct: 150 VQERRFCINPNAGFVHQLQEYEAIYLAKLTIQMM 183
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.138 0.436
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,110,340
Number of Sequences: 37866
Number of extensions: 274078
Number of successful extensions: 914
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 61
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 821
Number of HSP's gapped (non-prelim): 93
length of query: 198
length of database: 18,247,518
effective HSP length: 97
effective length of query: 101
effective length of database: 14,574,516
effective search space: 1472026116
effective search space used: 1472026116
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.