Search of human proteins with 58332438

Search of human proteins with 58332438

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|58332438 steroid 5 alpha-reductase 2-like 2 [Homo sapiens]
         (363 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|58332438 steroid 5 alpha-reductase 2-like 2 [Homo sapiens]         759   0.0  
gi|24475816 glycoprotein, synaptic 2 [Homo sapiens]                   348   3e-96
gi|239751670 PREDICTED: similar to hCG16318 [Homo sapiens]            172   6e-43
gi|39812447 3-oxo-5 alpha-steroid 4-dehydrogenase 2 [Homo sapiens]     46   6e-05
gi|4507201 steroid-5-alpha-reductase 1 [Homo sapiens]                  39   0.009
gi|13375785 steroid 5 alpha-reductase 3 [Homo sapiens]                 34   0.18 
gi|150378498 fragile site-associated protein [Homo sapiens]            32   0.68 
gi|54873613 agrin [Homo sapiens]                                       31   1.5  
gi|195947407 excision repair cross-complementing rodent repair d...    29   5.8  
gi|15834617 excision repair cross-complementing rodent repair de...    29   5.8  
gi|237512949 zinc finger protein 138 isoform 1 [Homo sapiens]          29   7.5  
gi|11863152 jumonji, AT rich interactive domain 2 protein [Homo ...    29   7.5  
gi|117168248 protein tyrosine phosphatase-like A domain containi...    29   7.5  
gi|148539848 desmocollin 3 isoform Dsc3b preproprotein [Homo sap...    28   9.8  
gi|148539846 desmocollin 3 isoform Dsc3a preproprotein [Homo sap...    28   9.8  

>gi|58332438 steroid 5 alpha-reductase 2-like 2 [Homo sapiens]
          Length = 363

 Score =  759 bits (1959), Expect = 0.0
 Identities = 363/363 (100%), Positives = 363/363 (100%)

Query: 1   MFKRHKSLASERKRALLSQRATRFILKDDMRNFHFLSKLVLSAGPLRPTPAVKHSKTTHF 60
           MFKRHKSLASERKRALLSQRATRFILKDDMRNFHFLSKLVLSAGPLRPTPAVKHSKTTHF
Sbjct: 1   MFKRHKSLASERKRALLSQRATRFILKDDMRNFHFLSKLVLSAGPLRPTPAVKHSKTTHF 60

Query: 61  EIEIFDAQTRKQICILDKVTQSSTIHDVKQKFHKACPKWYPSRVGLQLECGGPFLKDYIT 120
           EIEIFDAQTRKQICILDKVTQSSTIHDVKQKFHKACPKWYPSRVGLQLECGGPFLKDYIT
Sbjct: 61  EIEIFDAQTRKQICILDKVTQSSTIHDVKQKFHKACPKWYPSRVGLQLECGGPFLKDYIT 120

Query: 121 IQSIAASSIVTLYATDLGQQVSWTTVFLAEYTGPLLIYLLFYLRIPCIYDGKESARRLRH 180
           IQSIAASSIVTLYATDLGQQVSWTTVFLAEYTGPLLIYLLFYLRIPCIYDGKESARRLRH
Sbjct: 121 IQSIAASSIVTLYATDLGQQVSWTTVFLAEYTGPLLIYLLFYLRIPCIYDGKESARRLRH 180

Query: 181 PVVHLACFCHCIHYIRYLLETLFVHKVSAGHTPLKNLIMSCAFYWGFTSWIAYYINHPLY 240
           PVVHLACFCHCIHYIRYLLETLFVHKVSAGHTPLKNLIMSCAFYWGFTSWIAYYINHPLY
Sbjct: 181 PVVHLACFCHCIHYIRYLLETLFVHKVSAGHTPLKNLIMSCAFYWGFTSWIAYYINHPLY 240

Query: 241 TPPSFGNRQITVSAINFLICEAGNHFINVMLSHPNHTGNNACFPSPNYNPFTWMFFLVSC 300
           TPPSFGNRQITVSAINFLICEAGNHFINVMLSHPNHTGNNACFPSPNYNPFTWMFFLVSC
Sbjct: 241 TPPSFGNRQITVSAINFLICEAGNHFINVMLSHPNHTGNNACFPSPNYNPFTWMFFLVSC 300

Query: 301 PNYTYEIGSWISFTVMTQTLPVGIFTLLMSIQMSLWAQKKHKIYLRKFNSYIHRKSAMIP 360
           PNYTYEIGSWISFTVMTQTLPVGIFTLLMSIQMSLWAQKKHKIYLRKFNSYIHRKSAMIP
Sbjct: 301 PNYTYEIGSWISFTVMTQTLPVGIFTLLMSIQMSLWAQKKHKIYLRKFNSYIHRKSAMIP 360

Query: 361 FIL 363
           FIL
Sbjct: 361 FIL 363


>gi|24475816 glycoprotein, synaptic 2 [Homo sapiens]
          Length = 308

 Score =  348 bits (894), Expect = 3e-96
 Identities = 158/306 (51%), Positives = 210/306 (68%), Gaps = 1/306 (0%)

Query: 59  HFEIEIFDAQTRKQICILDKVTQSSTIHDVKQKFHKACPKWYPSRVGLQLECGGPFLKDY 118
           H+E+EI DA+TR+++C LDKV   +TI ++K  F K  P+WYP+R  L+L+  G  LKD 
Sbjct: 3   HYEVEILDAKTREKLCFLDKVEPHATIAEIKNLFTKTHPQWYPARQSLRLDPKGKSLKDE 62

Query: 119 ITIQSIAASSIVTLYATDLGQQVSWTTVFLAEYTGPLLIYLLFYLRIPCIYDGKESARRL 178
             +Q +   +  TLY  DLG Q+SW TVFL EY GPL IYLLFY R+P IY  K      
Sbjct: 63  DVLQKLPVGTTATLYFRDLGAQISWVTVFLTEYAGPLFIYLLFYFRVPFIYGHKYDFTSS 122

Query: 179 RHPVVHLACFCHCIHYIRYLLETLFVHKVSAGHTPLKNLIMSCAFYWGFTSWIAYYINHP 238
           RH VVHLAC CH  HYI+ LLETLFVH+ S G  PL+N+  +C +YWGF +W+AYYINHP
Sbjct: 123 RHTVVHLACICHSFHYIKRLLETLFVHRFSHGTMPLRNIFKNCTYYWGFAAWMAYYINHP 182

Query: 239 LYTPPSFGNRQITVSAINFLICEAGNHFINVMLSHPNHTGNNA-CFPSPNYNPFTWMFFL 297
           LYTPP++G +Q+ ++   F+IC+ GN  I++ L      G+     P P  NPFTW+F L
Sbjct: 183 LYTPPTYGAQQVKLALAIFVICQLGNFSIHMALRDLRPAGSKTRKIPYPTKNPFTWLFLL 242

Query: 298 VSCPNYTYEIGSWISFTVMTQTLPVGIFTLLMSIQMSLWAQKKHKIYLRKFNSYIHRKSA 357
           VSCPNYTYE+GSWI F +MTQ LPV +F+L+   QM++WA+ KH+ YL++F  Y   +  
Sbjct: 243 VSCPNYTYEVGSWIGFAIMTQCLPVALFSLVGFTQMTIWAKGKHRSYLKEFRDYPPLRMP 302

Query: 358 MIPFIL 363
           +IPF+L
Sbjct: 303 IIPFLL 308


>gi|239751670 PREDICTED: similar to hCG16318 [Homo sapiens]
          Length = 166

 Score =  172 bits (435), Expect = 6e-43
 Identities = 73/145 (50%), Positives = 103/145 (71%), Gaps = 1/145 (0%)

Query: 220 SCAFYWGFTSWIAYYINHPLYTPPSFGNRQITVSAINFLICEAGNHFINVMLSHPNHTGN 279
           +C +YWGF +W+AYYINHPLYTPP++G +Q+ ++   F+IC+ GN  I++ L      G+
Sbjct: 22  NCTYYWGFAAWMAYYINHPLYTPPTYGAQQVKLALAIFVICQLGNFSIHMALRDLRPAGS 81

Query: 280 NAC-FPSPNYNPFTWMFFLVSCPNYTYEIGSWISFTVMTQTLPVGIFTLLMSIQMSLWAQ 338
                P P  NPFTW+F LVSCPNYTYE+GSWI F +MTQ LPV +F+L+   QM++WA+
Sbjct: 82  KTRKIPYPTKNPFTWLFLLVSCPNYTYEVGSWIGFAIMTQCLPVALFSLVGFTQMTIWAK 141

Query: 339 KKHKIYLRKFNSYIHRKSAMIPFIL 363
            KH+ YL++F  Y   +  +IPF+L
Sbjct: 142 GKHRSYLKEFRDYPPLRMPIIPFLL 166


>gi|39812447 3-oxo-5 alpha-steroid 4-dehydrogenase 2 [Homo sapiens]
          Length = 254

 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 24/69 (34%), Positives = 34/69 (49%)

Query: 294 MFFLVSCPNYTYEIGSWISFTVMTQTLPVGIFTLLMSIQMSLWAQKKHKIYLRKFNSYIH 353
           +F  VS  N+  EI  WI + + T +LP   F       + L A   H+ YL+ F  Y  
Sbjct: 185 LFTYVSGANFLGEIIEWIGYALATWSLPALAFAFFSLCFLGLRAFHHHRFYLKMFEDYPK 244

Query: 354 RKSAMIPFI 362
            + A+IPFI
Sbjct: 245 SRKALIPFI 253


>gi|4507201 steroid-5-alpha-reductase 1 [Homo sapiens]
          Length = 259

 Score = 38.5 bits (88), Expect = 0.009
 Identities = 20/69 (28%), Positives = 34/69 (49%)

Query: 294 MFFLVSCPNYTYEIGSWISFTVMTQTLPVGIFTLLMSIQMSLWAQKKHKIYLRKFNSYIH 353
           +F  V+  NY  EI  W  + + + ++    F       +S  A++ H+ YLRKF  Y  
Sbjct: 190 LFEYVTAANYFGEIMEWCGYALASWSVQGAAFAFFTFCFLSGRAKEHHEWYLRKFEEYPK 249

Query: 354 RKSAMIPFI 362
            +  +IPF+
Sbjct: 250 FRKIIIPFL 258


>gi|13375785 steroid 5 alpha-reductase 3 [Homo sapiens]
          Length = 318

 Score = 34.3 bits (77), Expect = 0.18
 Identities = 23/75 (30%), Positives = 33/75 (44%), Gaps = 2/75 (2%)

Query: 290 PFTWMFFLVSCPNYTYEIGSWISFTVM--TQTLPVGIFTLLMSIQMSLWAQKKHKIYLRK 347
           PF   F  VS PNY  E+  ++S  V      L   +    +    +L A   H+ Y  K
Sbjct: 243 PFGDWFEYVSSPNYLAELMIYVSMAVTFGFHNLTWWLVVTNVFFNQALSAFLSHQFYKSK 302

Query: 348 FNSYIHRKSAMIPFI 362
           F SY   + A +PF+
Sbjct: 303 FVSYPKHRKAFLPFL 317


>gi|150378498 fragile site-associated protein [Homo sapiens]
          Length = 5005

 Score = 32.3 bits (72), Expect = 0.68
 Identities = 24/77 (31%), Positives = 31/77 (40%), Gaps = 9/77 (11%)

Query: 252  VSAINFLICEAGNHFINVMLSHPNHTGNNACFPSPNYNPFTWMFFLVSCPNYTY------ 305
            +S     + E G  F   M  H NH    ACF  PN+   +W  F +  PN  +      
Sbjct: 4638 ISLFQIPLPEDGMQFGGSMSLHGNHM-TLACFHGPNFRSKSWALFHLEEPNIAFWTEAQK 4696

Query: 306  --EIGSWISFTVMTQTL 320
              E GS    T + QTL
Sbjct: 4697 IWEDGSSDHSTYIVQTL 4713


>gi|54873613 agrin [Homo sapiens]
          Length = 2045

 Score = 31.2 bits (69), Expect = 1.5
 Identities = 17/47 (36%), Positives = 26/47 (55%), Gaps = 1/47 (2%)

Query: 112  GPFLKDYITIQSIAASSIVTLYATDLGQQVSWTTVFLAEYTGPLLIY 158
            GPFL D+     +    + T +A DLG++++   VFLA     LL+Y
Sbjct: 1634 GPFLADFNGFSHLELRGLHT-FARDLGEKMALEVVFLARGPSGLLLY 1679


>gi|195947407 excision repair cross-complementing rodent repair
           deficiency, complementation group 2 protein isoform 2
           [Homo sapiens]
          Length = 405

 Score = 29.3 bits (64), Expect = 5.8
 Identities = 33/120 (27%), Positives = 49/120 (40%), Gaps = 13/120 (10%)

Query: 69  TRKQICILDKVTQSSTIHDVKQKFHKACPKWYPSRVGLQLECGGPFLKDYITIQSIAASS 128
           +RK +CI  +VT      DV  K H     +   R   Q +   P  + Y    +     
Sbjct: 87  SRKNLCIHPEVTPLRFGKDVDGKCHSLTASYV--RAQYQHDTSLPHCRFYEEFDAHGREV 144

Query: 129 IVT--LYATD----LGQQVSWTTVFLAEYT---GPLLIYLLFYLRIPCIYD--GKESARR 177
            +   +Y  D    LG++  W   FLA Y+     +++Y   YL  P I D   KE AR+
Sbjct: 145 PLPAGIYNLDDLKALGRRQGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARK 204


>gi|15834617 excision repair cross-complementing rodent repair
           deficiency, complementation group 2 protein isoform 1
           [Homo sapiens]
          Length = 760

 Score = 29.3 bits (64), Expect = 5.8
 Identities = 33/120 (27%), Positives = 49/120 (40%), Gaps = 13/120 (10%)

Query: 69  TRKQICILDKVTQSSTIHDVKQKFHKACPKWYPSRVGLQLECGGPFLKDYITIQSIAASS 128
           +RK +CI  +VT      DV  K H     +   R   Q +   P  + Y    +     
Sbjct: 111 SRKNLCIHPEVTPLRFGKDVDGKCHSLTASYV--RAQYQHDTSLPHCRFYEEFDAHGREV 168

Query: 129 IVT--LYATD----LGQQVSWTTVFLAEYT---GPLLIYLLFYLRIPCIYD--GKESARR 177
            +   +Y  D    LG++  W   FLA Y+     +++Y   YL  P I D   KE AR+
Sbjct: 169 PLPAGIYNLDDLKALGRRQGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARK 228


>gi|237512949 zinc finger protein 138 isoform 1 [Homo sapiens]
          Length = 293

 Score = 28.9 bits (63), Expect = 7.5
 Identities = 13/43 (30%), Positives = 25/43 (58%), Gaps = 5/43 (11%)

Query: 52  VKHSKTTHFEIEIFDAQTRKQICILDKVTQSSTIHDVKQKFHK 94
           ++H++  HF  +  D    K +C+L ++TQ   IH  ++ F+K
Sbjct: 133 IRHTENKHFRCKECD----KSLCMLSRLTQHKKIH-TRENFYK 170


>gi|11863152 jumonji, AT rich interactive domain 2 protein [Homo
           sapiens]
          Length = 1246

 Score = 28.9 bits (63), Expect = 7.5
 Identities = 24/81 (29%), Positives = 38/81 (46%), Gaps = 14/81 (17%)

Query: 3   KRHKSLASERKRALLSQRATRFILKDDMRNFHFLSKLVLSAGPLRPTPAVKHSKTTHFEI 62
           K  K  A+  K A+   +A R ++KD   N H            +P+ AV H  T   + 
Sbjct: 334 KTVKYTATVTKGAVTYTKAKRELVKDTKPNHH------------KPSSAVNH--TISGKT 379

Query: 63  EIFDAQTRKQICILDKVTQSS 83
           E  +A+TRKQ+  L   ++S+
Sbjct: 380 ESSNAKTRKQVLSLGGASKST 400


>gi|117168248 protein tyrosine phosphatase-like A domain containing
           1 [Homo sapiens]
          Length = 362

 Score = 28.9 bits (63), Expect = 7.5
 Identities = 9/45 (20%), Positives = 26/45 (57%)

Query: 291 FTWMFFLVSCPNYTYEIGSWISFTVMTQTLPVGIFTLLMSIQMSL 335
           F + F++++C +  +++ +W+ +T+     P+G     +S+  S+
Sbjct: 257 FRYSFYMLTCIDMDWKVLTWLRYTLWIPLYPLGCLAEAVSVIQSI 301


>gi|148539848 desmocollin 3 isoform Dsc3b preproprotein [Homo
           sapiens]
          Length = 839

 Score = 28.5 bits (62), Expect = 9.8
 Identities = 28/100 (28%), Positives = 44/100 (44%), Gaps = 5/100 (5%)

Query: 40  VLSAGPLRPTPAVKHS-KTTHFEIEIFDA--QTRKQICIL--DKVTQSSTIHDVKQKFHK 94
           VL+ G +    AV  S K   F I + D   QT+K++ +L   +   S T H  +    +
Sbjct: 73  VLNDGSVYTARAVALSDKKRSFTIWLSDKRKQTQKEVTVLLEHQKKVSKTRHTRETVLRR 132

Query: 95  ACPKWYPSRVGLQLECGGPFLKDYITIQSIAASSIVTLYA 134
           A  +W P    +Q    GPF      ++S AA +    Y+
Sbjct: 133 AKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQNYTVFYS 172


>gi|148539846 desmocollin 3 isoform Dsc3a preproprotein [Homo
           sapiens]
          Length = 896

 Score = 28.5 bits (62), Expect = 9.8
 Identities = 28/100 (28%), Positives = 44/100 (44%), Gaps = 5/100 (5%)

Query: 40  VLSAGPLRPTPAVKHS-KTTHFEIEIFDA--QTRKQICIL--DKVTQSSTIHDVKQKFHK 94
           VL+ G +    AV  S K   F I + D   QT+K++ +L   +   S T H  +    +
Sbjct: 73  VLNDGSVYTARAVALSDKKRSFTIWLSDKRKQTQKEVTVLLEHQKKVSKTRHTRETVLRR 132

Query: 95  ACPKWYPSRVGLQLECGGPFLKDYITIQSIAASSIVTLYA 134
           A  +W P    +Q    GPF      ++S AA +    Y+
Sbjct: 133 AKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQNYTVFYS 172


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.139    0.452 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,836,644
Number of Sequences: 37866
Number of extensions: 579416
Number of successful extensions: 1352
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1339
Number of HSP's gapped (non-prelim): 19
length of query: 363
length of database: 18,247,518
effective HSP length: 104
effective length of query: 259
effective length of database: 14,309,454
effective search space: 3706148586
effective search space used: 3706148586
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.