Guide to the Human Genome
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Search of human proteins with 5803185

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5803185 synaptophysin-like 1 isoform a [Homo sapiens]
         (259 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5803185 synaptophysin-like 1 isoform a [Homo sapiens]              533   e-152
gi|33239443 synaptophysin-like 1 isoform b [Homo sapiens]             499   e-141
gi|27764867 synaptophysin [Homo sapiens]                              209   2e-54
gi|194018518 synaptoporin isoform 1 [Homo sapiens]                    201   4e-52
gi|105554421 mitsugumin 29 [Homo sapiens]                             198   3e-51
gi|21389481 synaptoporin isoform 2 [Homo sapiens]                     185   3e-47
gi|54792073 mucolipin 2 [Homo sapiens]                                 31   0.94 
gi|45594240 limbic system-associated membrane protein [Homo sapi...    30   1.6  
gi|145611446 tumor protein p53 inducible protein 5 [Homo sapiens]      30   2.7  
gi|6631112 synaptogyrin 3 [Homo sapiens]                               29   4.7  
gi|119964726 insulin-like growth factor 2 receptor precursor [Ho...    28   6.1  
gi|14140236 solute carrier family 5 (low affinity glucose cotran...    28   6.1  
gi|169203160 PREDICTED: hypothetical protein [Homo sapiens]            28   8.0  
gi|169203656 PREDICTED: hypothetical protein [Homo sapiens]            28   8.0  
gi|169202387 PREDICTED: hypothetical protein [Homo sapiens]            28   8.0  

>gi|5803185 synaptophysin-like 1 isoform a [Homo sapiens]
          Length = 259

 Score =  533 bits (1373), Expect = e-152
 Identities = 259/259 (100%), Positives = 259/259 (100%)

Query: 1   MAPNIYLVRQRISRLGQRMSGFQINLNPLKEPLGFIKVLEWIASIFAFATCGGFKGQTEI 60
           MAPNIYLVRQRISRLGQRMSGFQINLNPLKEPLGFIKVLEWIASIFAFATCGGFKGQTEI
Sbjct: 1   MAPNIYLVRQRISRLGQRMSGFQINLNPLKEPLGFIKVLEWIASIFAFATCGGFKGQTEI 60

Query: 61  QVNCPPAVTENKTVTATFGYPFRLNEASFQPPPGVNICDVNWKDYVLIGDYSSSAQFYVT 120
           QVNCPPAVTENKTVTATFGYPFRLNEASFQPPPGVNICDVNWKDYVLIGDYSSSAQFYVT
Sbjct: 61  QVNCPPAVTENKTVTATFGYPFRLNEASFQPPPGVNICDVNWKDYVLIGDYSSSAQFYVT 120

Query: 121 FAVFVFLYCIAALLLYVGYTSLYLDSRKLPMIDFVVTLVATFLWLVSTSAWAKALTDIKI 180
           FAVFVFLYCIAALLLYVGYTSLYLDSRKLPMIDFVVTLVATFLWLVSTSAWAKALTDIKI
Sbjct: 121 FAVFVFLYCIAALLLYVGYTSLYLDSRKLPMIDFVVTLVATFLWLVSTSAWAKALTDIKI 180

Query: 181 ATGHNIIDELPPCKKKAVLCYFGSVTSMGSLNVSVIFGFLNMILWGGNAWFVYKETSLHS 240
           ATGHNIIDELPPCKKKAVLCYFGSVTSMGSLNVSVIFGFLNMILWGGNAWFVYKETSLHS
Sbjct: 181 ATGHNIIDELPPCKKKAVLCYFGSVTSMGSLNVSVIFGFLNMILWGGNAWFVYKETSLHS 240

Query: 241 PSNTSAPHSQGGIPPPTGI 259
           PSNTSAPHSQGGIPPPTGI
Sbjct: 241 PSNTSAPHSQGGIPPPTGI 259


>gi|33239443 synaptophysin-like 1 isoform b [Homo sapiens]
          Length = 241

 Score =  499 bits (1284), Expect = e-141
 Identities = 241/241 (100%), Positives = 241/241 (100%)

Query: 19  MSGFQINLNPLKEPLGFIKVLEWIASIFAFATCGGFKGQTEIQVNCPPAVTENKTVTATF 78
           MSGFQINLNPLKEPLGFIKVLEWIASIFAFATCGGFKGQTEIQVNCPPAVTENKTVTATF
Sbjct: 1   MSGFQINLNPLKEPLGFIKVLEWIASIFAFATCGGFKGQTEIQVNCPPAVTENKTVTATF 60

Query: 79  GYPFRLNEASFQPPPGVNICDVNWKDYVLIGDYSSSAQFYVTFAVFVFLYCIAALLLYVG 138
           GYPFRLNEASFQPPPGVNICDVNWKDYVLIGDYSSSAQFYVTFAVFVFLYCIAALLLYVG
Sbjct: 61  GYPFRLNEASFQPPPGVNICDVNWKDYVLIGDYSSSAQFYVTFAVFVFLYCIAALLLYVG 120

Query: 139 YTSLYLDSRKLPMIDFVVTLVATFLWLVSTSAWAKALTDIKIATGHNIIDELPPCKKKAV 198
           YTSLYLDSRKLPMIDFVVTLVATFLWLVSTSAWAKALTDIKIATGHNIIDELPPCKKKAV
Sbjct: 121 YTSLYLDSRKLPMIDFVVTLVATFLWLVSTSAWAKALTDIKIATGHNIIDELPPCKKKAV 180

Query: 199 LCYFGSVTSMGSLNVSVIFGFLNMILWGGNAWFVYKETSLHSPSNTSAPHSQGGIPPPTG 258
           LCYFGSVTSMGSLNVSVIFGFLNMILWGGNAWFVYKETSLHSPSNTSAPHSQGGIPPPTG
Sbjct: 181 LCYFGSVTSMGSLNVSVIFGFLNMILWGGNAWFVYKETSLHSPSNTSAPHSQGGIPPPTG 240

Query: 259 I 259
           I
Sbjct: 241 I 241


>gi|27764867 synaptophysin [Homo sapiens]
          Length = 313

 Score =  209 bits (532), Expect = 2e-54
 Identities = 106/243 (43%), Positives = 150/243 (61%), Gaps = 7/243 (2%)

Query: 15  LGQRMSGFQINLNPLKEPLGFIKVLEWIASIFAFATCGGFKGQTEIQVNCPPAVTENKTV 74
           + Q ++G Q  +  +KEPLGF+KVL+W+ +IFAFATCG + G+ ++ V+C      + ++
Sbjct: 10  VNQLVAGGQFRV--VKEPLGFVKVLQWVFAIFAFATCGSYSGELQLSVDCANKTESDLSI 67

Query: 75  TATFGYPFRLNEASFQPPPGVNICDVNWKDYVLIGDYSSSAQFYVTFAVFVFLYCIAALL 134
              F YPFRL++  F  P     C        L+GDYSSSA+F+VT AVF FLY + AL 
Sbjct: 68  EVEFEYPFRLHQVYFDAPT----CRGGTTKVFLVGDYSSSAEFFVTVAVFAFLYSMGALA 123

Query: 135 LYVGYTSLYLDSRKLPMIDFVVTLVATFLWLVSTSAWAKALTDIKIATG-HNIIDELPPC 193
            Y+   + Y ++ K PM+DF+ T V  F+WLVS+SAWAK L+D+K+AT   NII E+P C
Sbjct: 124 TYIFLQNKYRENNKGPMLDFLATAVFAFMWLVSSSAWAKGLSDVKMATDPENIIKEMPVC 183

Query: 194 KKKAVLCYFGSVTSMGSLNVSVIFGFLNMILWGGNAWFVYKETSLHSPSNTSAPHSQGGI 253
           ++    C          LN SV+FGFLN++LW GN WFV+KET   +P   + P +    
Sbjct: 184 RQTGNTCKELRDPVTSGLNTSVVFGFLNLVLWVGNLWFVFKETGWAAPFLRAPPGAPEKQ 243

Query: 254 PPP 256
           P P
Sbjct: 244 PAP 246


>gi|194018518 synaptoporin isoform 1 [Homo sapiens]
          Length = 285

 Score =  201 bits (512), Expect = 4e-52
 Identities = 104/235 (44%), Positives = 149/235 (63%), Gaps = 15/235 (6%)

Query: 29  LKEPLGFIKVLEWIASIFAFATCGGFKGQTEIQVNCPPAVTENKTVTATFGYPFRLNEAS 88
           LKEPL F++ LE + +IFAFATCGG+ G   + V+C      N ++   F YPFRL++ +
Sbjct: 16  LKEPLAFLRALELLFAIFAFATCGGYSGGLRLSVDCVNKTESNLSIDIAFAYPFRLHQVT 75

Query: 89  FQPPPGVNICDVNWKDYV-LIGDYSSSAQFYVTFAVFVFLYCIAALLLYVGYTSLYLDSR 147
           F+ P     C+   +  + LIGD SSSA+F+VT AVF FLY +AA ++Y+ + + Y ++ 
Sbjct: 76  FEVPT----CEGKERQKLALIGDSSSSAEFFVTVAVFAFLYSLAATVVYIFFQNKYRENN 131

Query: 148 KLPMIDFVVTLVATFLWLVSTSAWAKALTDIKIATG-HNIIDELPPCKKKAVLCYFGSVT 206
           + P+IDF+VT+V +FLWLV +SAWAK L+D+K+AT    ++  +  CK+ +  C      
Sbjct: 132 RGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKVATDPKEVLLLMSACKQPSNKCMAIHSP 191

Query: 207 SMGSLNVSVIFGFLNMILWGGNAWFVYKETSLHSPSNT---------SAPHSQGG 252
            M SLN SV+FGFLN ILW GN WFV+KET  HS             S+ ++QGG
Sbjct: 192 VMSSLNTSVVFGFLNFILWAGNIWFVFKETGWHSSGQRYLSDPMEKHSSSYNQGG 246


>gi|105554421 mitsugumin 29 [Homo sapiens]
          Length = 272

 Score =  198 bits (504), Expect = 3e-51
 Identities = 92/214 (42%), Positives = 139/214 (64%), Gaps = 7/214 (3%)

Query: 29  LKEPLGFIKVLEWIASIFAFATCGGFKGQTEIQVNCPPAVTENKTVTATFGYPFRLNEAS 88
           L+EPLGFIKVL+W+ +IFAF +CG + G+T   V C     +  ++   FGYPFRL+   
Sbjct: 31  LEEPLGFIKVLQWLFAIFAFGSCGSYSGETGAMVRCNNEAKDVSSIIVAFGYPFRLHRIQ 90

Query: 89  FQPPPGVNICDV--NWKDYVLIGDYSSSAQFYVTFAVFVFLYCIAALLLYVGYTSLYLDS 146
           ++ P    +CD   + K   L+GD+S+ A+F+VT  +F F Y +AAL++Y+ + +LY ++
Sbjct: 91  YEMP----LCDEESSSKTMHLMGDFSAPAEFFVTLGIFSFFYTMAALVIYLRFHNLYTEN 146

Query: 147 RKLPMIDFVVTLVATFLWLVSTSAWAKALTDIKIAT-GHNIIDELPPCKKKAVLCYFGSV 205
           ++ P++DF VT+  TF WLV+ +AW K LTD+K AT   ++   +  C  +  +C  G+ 
Sbjct: 147 KRFPLVDFCVTVSFTFFWLVAAAAWGKGLTDVKGATRPSSLTAAMSVCHGEEAVCSAGAT 206

Query: 206 TSMGSLNVSVIFGFLNMILWGGNAWFVYKETSLH 239
            SMG  N+SV+FGF+N  LW GN WFV+KET  H
Sbjct: 207 PSMGLANISVLFGFINFFLWAGNCWFVFKETPWH 240


>gi|21389481 synaptoporin isoform 2 [Homo sapiens]
          Length = 265

 Score =  185 bits (470), Expect = 3e-47
 Identities = 96/220 (43%), Positives = 138/220 (62%), Gaps = 15/220 (6%)

Query: 44  SIFAFATCGGFKGQTEIQVNCPPAVTENKTVTATFGYPFRLNEASFQPPPGVNICDVNWK 103
           +IFAFATCGG+ G   + V+C      N ++   F YPFRL++ +F+ P     C+   +
Sbjct: 11  AIFAFATCGGYSGGLRLSVDCVNKTESNLSIDIAFAYPFRLHQVTFEVPT----CEGKER 66

Query: 104 DYV-LIGDYSSSAQFYVTFAVFVFLYCIAALLLYVGYTSLYLDSRKLPMIDFVVTLVATF 162
             + LIGD SSSA+F+VT AVF FLY +AA ++Y+ + + Y ++ + P+IDF+VT+V +F
Sbjct: 67  QKLALIGDSSSSAEFFVTVAVFAFLYSLAATVVYIFFQNKYRENNRGPLIDFIVTVVFSF 126

Query: 163 LWLVSTSAWAKALTDIKIATG-HNIIDELPPCKKKAVLCYFGSVTSMGSLNVSVIFGFLN 221
           LWLV +SAWAK L+D+K+AT    ++  +  CK+ +  C       M SLN SV+FGFLN
Sbjct: 127 LWLVGSSAWAKGLSDVKVATDPKEVLLLMSACKQPSNKCMAIHSPVMSSLNTSVVFGFLN 186

Query: 222 MILWGGNAWFVYKETSLHSPSNT---------SAPHSQGG 252
            ILW GN WFV+KET  HS             S+ ++QGG
Sbjct: 187 FILWAGNIWFVFKETGWHSSGQRYLSDPMEKHSSSYNQGG 226


>gi|54792073 mucolipin 2 [Homo sapiens]
          Length = 566

 Score = 31.2 bits (69), Expect = 0.94
 Identities = 16/46 (34%), Positives = 24/46 (52%)

Query: 103 KDYVLIGDYSSSAQFYVTFAVFVFLYCIAALLLYVGYTSLYLDSRK 148
           KD  + G    +AQ+ + F  FV + C+A+L+L      L L  RK
Sbjct: 275 KDLNIFGSTQKNAQYVLVFDAFVIVICLASLILCTRSIVLALRLRK 320


>gi|45594240 limbic system-associated membrane protein [Homo
           sapiens]
          Length = 338

 Score = 30.4 bits (67), Expect = 1.6
 Identities = 17/38 (44%), Positives = 22/38 (57%), Gaps = 1/38 (2%)

Query: 57  QTEIQVNCPPAVTENKTVTATFGYPFRLN-EASFQPPP 93
           Q ++ VN PP +TE+K+  AT G    L  EAS  P P
Sbjct: 210 QVKVTVNYPPTITESKSNEATTGRQASLKCEASAVPAP 247


>gi|145611446 tumor protein p53 inducible protein 5 [Homo sapiens]
          Length = 782

 Score = 29.6 bits (65), Expect = 2.7
 Identities = 32/112 (28%), Positives = 46/112 (41%), Gaps = 12/112 (10%)

Query: 36  IKVLEWIASIFAFATCGGFKGQTEIQVNCPPAVTE-NKTVTATFGYPFR----LNEASFQ 90
           I VL  IA+    A    F  +   +    P + E N TV    GY        +   FQ
Sbjct: 605 IGVLAVIANGMVIAFTSEFIPRVVYKYRYSPCLKEGNSTVDCLKGYVNHSLSVFHTKDFQ 664

Query: 91  PPPGV----NICDVNWKDYVLIGDYSSSAQFYVTFAV---FVFLYCIAALLL 135
            P G+    N+    ++DY    DY+ S QF+   A+   FV L+   AL +
Sbjct: 665 DPDGIEGSENVTLCRYRDYRNPPDYNFSEQFWFLLAIRLAFVILFEHVALCI 716


>gi|6631112 synaptogyrin 3 [Homo sapiens]
          Length = 229

 Score = 28.9 bits (63), Expect = 4.7
 Identities = 20/68 (29%), Positives = 33/68 (48%), Gaps = 6/68 (8%)

Query: 112 SSSAQFYVTFAVFVFLYCIAALLLYVGY--TSLYLDSRKLPMIDFVVTLVATFLWLVS-- 167
           + + +F V   +  FL C A LLL V +   S   D R+  ++D   + + +FLW V   
Sbjct: 65  AGACRFGVALGLGAFLACAAFLLLDVRFQQISSVRDRRRAVLLDLGFSGLWSFLWFVGFC 124

Query: 168 --TSAWAK 173
             T+ W +
Sbjct: 125 FLTNQWQR 132


>gi|119964726 insulin-like growth factor 2 receptor precursor [Homo
           sapiens]
          Length = 2491

 Score = 28.5 bits (62), Expect = 6.1
 Identities = 15/33 (45%), Positives = 17/33 (51%), Gaps = 2/33 (6%)

Query: 20  SGFQINLNPLKEPLGFIKVLEWIASIFAFATCG 52
           SGF  NLNPL    G+   +  I  IF F  CG
Sbjct: 941 SGFVFNLNPLNSSQGY--NVSGIGKIFMFNVCG 971


>gi|14140236 solute carrier family 5 (low affinity glucose
           cotransporter), member 4 [Homo sapiens]
          Length = 659

 Score = 28.5 bits (62), Expect = 6.1
 Identities = 13/30 (43%), Positives = 17/30 (56%)

Query: 46  FAFATCGGFKGQTEIQVNCPPAVTENKTVT 75
           FAF   GG++  TE  VN  P+V E   +T
Sbjct: 221 FAFNEVGGYESFTEKYVNATPSVVEGDNLT 250


>gi|169203160 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 638

 Score = 28.1 bits (61), Expect = 8.0
 Identities = 30/132 (22%), Positives = 52/132 (39%), Gaps = 13/132 (9%)

Query: 74  VTATFGYPFRLNEASFQPPPGVNICDVNWKDYVLIGDYSSSAQFYVTFAVFVFLYCIAAL 133
           VT  +GY    N   F     +N     W DY  +    S  +  VTF++  F+      
Sbjct: 270 VTFPYGYHAGFNHG-FNCAEAINFATPRWIDYGKVASQCSCGEARVTFSMDAFV-----R 323

Query: 134 LLYVGYTSLYLDSRKLPMIDFVVTLVATFLWLVSTSAWAKALTDIKIATG-HNIIDELPP 192
           +L      L+   + L ++D++   VA        S W + +   + A G  ++ + +  
Sbjct: 324 ILQPESYELWKHRQDLTVVDYMEPRVAE---SQEPSNWREDIALRRAALGLRHLRNHITS 380

Query: 193 CKKKAV---LCY 201
           C  + V   LCY
Sbjct: 381 CPTRTVAPRLCY 392


>gi|169203656 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 638

 Score = 28.1 bits (61), Expect = 8.0
 Identities = 30/132 (22%), Positives = 52/132 (39%), Gaps = 13/132 (9%)

Query: 74  VTATFGYPFRLNEASFQPPPGVNICDVNWKDYVLIGDYSSSAQFYVTFAVFVFLYCIAAL 133
           VT  +GY    N   F     +N     W DY  +    S  +  VTF++  F+      
Sbjct: 270 VTFPYGYHAGFNHG-FNCAEAINFATPRWIDYGKVASQCSCGEARVTFSMDAFV-----R 323

Query: 134 LLYVGYTSLYLDSRKLPMIDFVVTLVATFLWLVSTSAWAKALTDIKIATG-HNIIDELPP 192
           +L      L+   + L ++D++   VA        S W + +   + A G  ++ + +  
Sbjct: 324 ILQPESYELWKHRQDLTVVDYMEPRVAE---SQEPSNWREDIALRRAALGLRHLRNHITS 380

Query: 193 CKKKAV---LCY 201
           C  + V   LCY
Sbjct: 381 CPTRTVAPRLCY 392


>gi|169202387 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 638

 Score = 28.1 bits (61), Expect = 8.0
 Identities = 30/132 (22%), Positives = 52/132 (39%), Gaps = 13/132 (9%)

Query: 74  VTATFGYPFRLNEASFQPPPGVNICDVNWKDYVLIGDYSSSAQFYVTFAVFVFLYCIAAL 133
           VT  +GY    N   F     +N     W DY  +    S  +  VTF++  F+      
Sbjct: 270 VTFPYGYHAGFNHG-FNCAEAINFATPRWIDYGKVASQCSCGEARVTFSMDAFV-----R 323

Query: 134 LLYVGYTSLYLDSRKLPMIDFVVTLVATFLWLVSTSAWAKALTDIKIATG-HNIIDELPP 192
           +L      L+   + L ++D++   VA        S W + +   + A G  ++ + +  
Sbjct: 324 ILQPESYELWKHRQDLTVVDYMEPRVAE---SQEPSNWREDIALRRAALGLRHLRNHITS 380

Query: 193 CKKKAV---LCY 201
           C  + V   LCY
Sbjct: 381 CPTRTVAPRLCY 392


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.139    0.442 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,593,539
Number of Sequences: 37866
Number of extensions: 431089
Number of successful extensions: 1376
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1358
Number of HSP's gapped (non-prelim): 16
length of query: 259
length of database: 18,247,518
effective HSP length: 100
effective length of query: 159
effective length of database: 14,460,918
effective search space: 2299285962
effective search space used: 2299285962
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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