Guide to the Human Genome
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Search of human proteins with 5730085

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5730085 dynein, light chain, Tctex-type 1 [Homo sapiens]
         (113 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5730085 dynein, light chain, Tctex-type 1 [Homo sapiens]           233   3e-62
gi|239753813 PREDICTED: similar to dynein, light chain, Tctex-ty...   189   5e-49
gi|239748376 PREDICTED: hypothetical protein XP_002346645 [Homo ...   189   5e-49
gi|239742301 PREDICTED: hypothetical protein XP_002342481 [Homo ...   189   5e-49
gi|5730087 dynein, light chain, Tctex-type 3 [Homo sapiens]           147   2e-36
gi|229090471 Tctex1 domain containing 2 [Homo sapiens]                 56   5e-09
gi|61966721 Tctex1 domain containing 4 [Homo sapiens]                  44   2e-05
gi|239735600 Tctex1 domain containing 1 [Homo sapiens]                 44   4e-05
gi|169160677 PREDICTED: similar to Tctex1 domain containing 4 [H...    42   1e-04
gi|28372535 t-complex-associated-testis-expressed 3 [Homo sapiens]     35   0.017
gi|157785668 coiled-coil domain containing 39 [Homo sapiens]           29   0.70 
gi|126116565 MYC binding protein 2 [Homo sapiens]                      28   1.2  
gi|187828880 calcium channel, alpha 1A subunit isoform 3 [Homo s...    27   2.7  
gi|148762985 pseudouridylate synthase 7 homolog (S. cerevisiae)-...    27   4.6  
gi|148762948 pseudouridylate synthase 7 homolog (S. cerevisiae)-...    27   4.6  
gi|148762961 pseudouridylate synthase 7 homolog (S. cerevisiae)-...    27   4.6  
gi|19923626 apolipoprotein L4 isoform 1 [Homo sapiens]                 27   4.6  
gi|22035657 apolipoprotein L4 isoform 2 precursor [Homo sapiens]       27   4.6  
gi|153252003 sarcomeric mitochondrial creatine kinase precursor ...    26   6.0  
gi|153251984 sarcomeric mitochondrial creatine kinase precursor ...    26   6.0  
gi|153251982 sarcomeric mitochondrial creatine kinase precursor ...    26   6.0  

>gi|5730085 dynein, light chain, Tctex-type 1 [Homo sapiens]
          Length = 113

 Score =  233 bits (593), Expect = 3e-62
 Identities = 113/113 (100%), Positives = 113/113 (100%)

Query: 1   MEDYQAAEETAFVVDEVSNIVKEAIESAIGGNAYQHSKVNQWTTNVVEQTLSQLTKLGKP 60
           MEDYQAAEETAFVVDEVSNIVKEAIESAIGGNAYQHSKVNQWTTNVVEQTLSQLTKLGKP
Sbjct: 1   MEDYQAAEETAFVVDEVSNIVKEAIESAIGGNAYQHSKVNQWTTNVVEQTLSQLTKLGKP 60

Query: 61  FKYIVTCVIMQKNGAGLHTASSCFWDSSTDGSCTVRWENKTMYCIVSAFGLSI 113
           FKYIVTCVIMQKNGAGLHTASSCFWDSSTDGSCTVRWENKTMYCIVSAFGLSI
Sbjct: 61  FKYIVTCVIMQKNGAGLHTASSCFWDSSTDGSCTVRWENKTMYCIVSAFGLSI 113


>gi|239753813 PREDICTED: similar to dynein, light chain, Tctex-type
           1 [Homo sapiens]
          Length = 116

 Score =  189 bits (479), Expect = 5e-49
 Identities = 99/118 (83%), Positives = 102/118 (86%), Gaps = 7/118 (5%)

Query: 1   MEDYQAAEETAFVVDEVSNIVKEAIESAIG-----GNAYQHSKVNQWTTNVVEQTLSQLT 55
           M DYQA EETAF+V EVSN VKEAIES IG     GNAYQHSKVNQWTTNV EQTLSQL 
Sbjct: 1   MGDYQAVEETAFIV-EVSNTVKEAIESVIGAGRVGGNAYQHSKVNQWTTNV-EQTLSQLP 58

Query: 56  KLGKPFKYIVTCVIMQKNGAGLHTASSCFWDSSTDGSCTVRWENKTMYCIVSAFGLSI 113
           KLGKPFKYIVTCVI+QKNGAG + ASSCFWDSSTDGS TVRWENKTMYCIV AFGLSI
Sbjct: 59  KLGKPFKYIVTCVIIQKNGAGSYMASSCFWDSSTDGSYTVRWENKTMYCIVGAFGLSI 116


>gi|239748376 PREDICTED: hypothetical protein XP_002346645 [Homo
           sapiens]
          Length = 116

 Score =  189 bits (479), Expect = 5e-49
 Identities = 99/118 (83%), Positives = 102/118 (86%), Gaps = 7/118 (5%)

Query: 1   MEDYQAAEETAFVVDEVSNIVKEAIESAIG-----GNAYQHSKVNQWTTNVVEQTLSQLT 55
           M DYQA EETAF+V EVSN VKEAIES IG     GNAYQHSKVNQWTTNV EQTLSQL 
Sbjct: 1   MGDYQAVEETAFIV-EVSNTVKEAIESVIGAGRVGGNAYQHSKVNQWTTNV-EQTLSQLP 58

Query: 56  KLGKPFKYIVTCVIMQKNGAGLHTASSCFWDSSTDGSCTVRWENKTMYCIVSAFGLSI 113
           KLGKPFKYIVTCVI+QKNGAG + ASSCFWDSSTDGS TVRWENKTMYCIV AFGLSI
Sbjct: 59  KLGKPFKYIVTCVIIQKNGAGSYMASSCFWDSSTDGSYTVRWENKTMYCIVGAFGLSI 116


>gi|239742301 PREDICTED: hypothetical protein XP_002342481 [Homo
           sapiens]
          Length = 116

 Score =  189 bits (479), Expect = 5e-49
 Identities = 99/118 (83%), Positives = 102/118 (86%), Gaps = 7/118 (5%)

Query: 1   MEDYQAAEETAFVVDEVSNIVKEAIESAIG-----GNAYQHSKVNQWTTNVVEQTLSQLT 55
           M DYQA EETAF+V EVSN VKEAIES IG     GNAYQHSKVNQWTTNV EQTLSQL 
Sbjct: 1   MGDYQAVEETAFIV-EVSNTVKEAIESVIGAGRVGGNAYQHSKVNQWTTNV-EQTLSQLP 58

Query: 56  KLGKPFKYIVTCVIMQKNGAGLHTASSCFWDSSTDGSCTVRWENKTMYCIVSAFGLSI 113
           KLGKPFKYIVTCVI+QKNGAG + ASSCFWDSSTDGS TVRWENKTMYCIV AFGLSI
Sbjct: 59  KLGKPFKYIVTCVIIQKNGAGSYMASSCFWDSSTDGSYTVRWENKTMYCIVGAFGLSI 116


>gi|5730087 dynein, light chain, Tctex-type 3 [Homo sapiens]
          Length = 116

 Score =  147 bits (371), Expect = 2e-36
 Identities = 62/114 (54%), Positives = 86/114 (75%), Gaps = 1/114 (0%)

Query: 1   MEDYQA-AEETAFVVDEVSNIVKEAIESAIGGNAYQHSKVNQWTTNVVEQTLSQLTKLGK 59
           ME+Y    +E  F  +E  NIVKE ++  +GG  Y H+ +NQWT ++VEQ+L+ L KLGK
Sbjct: 1   MEEYHRHCDEVGFNAEEAHNIVKECVDGVLGGEDYNHNNINQWTASIVEQSLTHLVKLGK 60

Query: 60  PFKYIVTCVIMQKNGAGLHTASSCFWDSSTDGSCTVRWENKTMYCIVSAFGLSI 113
            +KYIVTC ++QK+  G HTASSCFWD+++DG+CTVRWEN+TM CIV+ F ++I
Sbjct: 61  AYKYIVTCAVVQKSAYGFHTASSCFWDTTSDGTCTVRWENRTMNCIVNVFAIAI 114


>gi|229090471 Tctex1 domain containing 2 [Homo sapiens]
          Length = 142

 Score = 56.2 bits (134), Expect = 5e-09
 Identities = 32/108 (29%), Positives = 58/108 (53%), Gaps = 5/108 (4%)

Query: 4   YQAAEETAFVVDEVSNIVKEAIESAIGGNAYQHSKVNQWTTNVVEQTLSQLTKLG-KPFK 62
           +Q     + V D +  ++KE + +A     Y   ++ Q T ++ E    +L ++G   +K
Sbjct: 35  FQQRFRPSVVKDCIHAVLKEELANA----EYSPEEMPQLTKHLSENIKDKLKEMGFDRYK 90

Query: 63  YIVTCVIMQKNGAGLHTASSCFWDSSTDGSCTVRWENKTMYCIVSAFG 110
            +V  VI ++ G G+  AS CFWD+ TD      + N +++C+V+AFG
Sbjct: 91  MVVQVVIGEQRGEGVFMASRCFWDADTDNYTHDVFMNDSLFCVVAAFG 138


>gi|61966721 Tctex1 domain containing 4 [Homo sapiens]
          Length = 221

 Score = 44.3 bits (103), Expect = 2e-05
 Identities = 23/95 (24%), Positives = 46/95 (48%), Gaps = 5/95 (5%)

Query: 22  KEAIESAIGGN----AYQHSKVNQWTTNVVEQTLSQLTKLGKP-FKYIVTCVIMQKNGAG 76
           + A+E+A+        Y   +  +    + EQ   +L +L  P +K + + V+  + G G
Sbjct: 124 QRALEAALAAGLHDACYSSDEAARLVRELCEQVHVRLRELSPPRYKLVCSVVLGPRAGQG 183

Query: 77  LHTASSCFWDSSTDGSCTVRWENKTMYCIVSAFGL 111
           +H  S   WD + DG  +V + N +++ + +  GL
Sbjct: 184 VHVVSRALWDVARDGLASVSYTNTSLFAVATVHGL 218


>gi|239735600 Tctex1 domain containing 1 [Homo sapiens]
          Length = 179

 Score = 43.5 bits (101), Expect = 4e-05
 Identities = 27/109 (24%), Positives = 49/109 (44%), Gaps = 1/109 (0%)

Query: 4   YQAAEETAFVVDEVSNIVKEAIESAIGGNAYQHSKVNQWTTNVVEQTLSQLTKLGKP-FK 62
           YQ      F V  V++I+K+ + S +    Y+     Q T  + E   +Q+  L  P +K
Sbjct: 68  YQLGPPKHFPVVTVNHILKDVVTSYLQVEEYEPELCRQMTKTISEVIKAQVKDLMIPRYK 127

Query: 63  YIVTCVIMQKNGAGLHTASSCFWDSSTDGSCTVRWENKTMYCIVSAFGL 111
            IV   I Q N   +   S C WD  +D   +  + N +++ + + + +
Sbjct: 128 LIVIVHIGQLNRQSILIGSRCLWDPKSDTFSSYVFRNSSLFALANVYAV 176


>gi|169160677 PREDICTED: similar to Tctex1 domain containing 4 [Homo
           sapiens]
          Length = 127

 Score = 42.0 bits (97), Expect = 1e-04
 Identities = 20/79 (25%), Positives = 39/79 (49%), Gaps = 1/79 (1%)

Query: 34  YQHSKVNQWTTNVVEQTLSQLTKLGKP-FKYIVTCVIMQKNGAGLHTASSCFWDSSTDGS 92
           Y   +  +    + EQ   +L +L  P +K + + V+  + G G+H  S   WD + DG 
Sbjct: 46  YSSDEPARLVRELCEQVHVRLRELSPPRYKLVCSVVLGPRAGQGVHVVSRALWDVARDGL 105

Query: 93  CTVRWENKTMYCIVSAFGL 111
            +V + N +++ + +  GL
Sbjct: 106 ASVSYTNTSLFAVATVHGL 124


>gi|28372535 t-complex-associated-testis-expressed 3 [Homo sapiens]
          Length = 198

 Score = 34.7 bits (78), Expect = 0.017
 Identities = 20/101 (19%), Positives = 44/101 (43%), Gaps = 1/101 (0%)

Query: 12  FVVDEVSNIVKEAIESAIGGNAYQHSKVNQWTTNVVEQTLSQLTKLG-KPFKYIVTCVIM 70
           F    V   V++ +  ++    Y     +  +  + ++ L  + + G   +K+I+  + +
Sbjct: 95  FQAHSVETKVQQILTESLKDVKYDDKVFSHLSLELADRILLAVKEFGYHRYKFIIKVLFI 154

Query: 71  QKNGAGLHTASSCFWDSSTDGSCTVRWENKTMYCIVSAFGL 111
           QK G  ++ AS   WD + D     + E ++   +V  F L
Sbjct: 155 QKTGQAINIASRWIWDIAWDSWVAAKHEAESYVALVLVFAL 195


>gi|157785668 coiled-coil domain containing 39 [Homo sapiens]
          Length = 941

 Score = 29.3 bits (64), Expect = 0.70
 Identities = 19/63 (30%), Positives = 32/63 (50%), Gaps = 1/63 (1%)

Query: 2   EDYQAAEETAFVVDEVSNIVKEAIESAIGGNAYQHSKVNQWTTNVVEQTLSQLTKLGKPF 61
           ED Q+ E T  V++ ++N VKE + S     ++Q SK  +     +E+   Q  KL K  
Sbjct: 752 EDIQSMENTLDVIEHLANNVKEKL-SEKQAYSFQLSKETEEQKPKLERVTKQCAKLTKEI 810

Query: 62  KYI 64
           + +
Sbjct: 811 RLL 813


>gi|126116565 MYC binding protein 2 [Homo sapiens]
          Length = 4640

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 7/87 (8%)

Query: 16   EVSNIVKEAIESAIGGNAYQH-SKVNQWTTNVVEQTLSQLTKLGKPFKYIVTCVIMQKNG 74
            ++S I+ + I+    G+  +  S+V   T N + +T+  LTK+ + F+  V C+   +  
Sbjct: 4132 QISEIIIKLIKDMAAGHLSEAWSRV---TKNAIAETIIALTKMEEEFRSPVRCIATTR-- 4186

Query: 75   AGLHTASSCFWDSS-TDGSCTVRWENK 100
              L  AS C  D    D   + RW  K
Sbjct: 4187 LWLALASLCVLDQDHVDRLSSGRWMGK 4213


>gi|187828880 calcium channel, alpha 1A subunit isoform 3 [Homo
           sapiens]
          Length = 2261

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 15/61 (24%), Positives = 23/61 (37%)

Query: 1   MEDYQAAEETAFVVDEVSNIVKEAIESAIGGNAYQHSKVNQWTTNVVEQTLSQLTKLGKP 60
           ME    AEE     DE     +   + A+     + SK +       E  L+ +  +G P
Sbjct: 393 MEWISKAEEVILAEDETDGEQRHPFDGALRRTTIKKSKTDLLNPEEAEDQLADIASVGSP 452

Query: 61  F 61
           F
Sbjct: 453 F 453


>gi|148762985 pseudouridylate synthase 7 homolog (S.
           cerevisiae)-like [Homo sapiens]
          Length = 701

 Score = 26.6 bits (57), Expect = 4.6
 Identities = 17/74 (22%), Positives = 37/74 (50%)

Query: 7   AEETAFVVDEVSNIVKEAIESAIGGNAYQHSKVNQWTTNVVEQTLSQLTKLGKPFKYIVT 66
           +E+   +VD  S   ++A   +   +   H  +N +  +V E+ LS+   +G P ++ + 
Sbjct: 105 SEKEDTIVDGTSKCEEKADVLSSFLDEKTHELLNNFACDVREKWLSKTELIGLPPEFSIG 164

Query: 67  CVIMQKNGAGLHTA 80
            ++ +   A LH+A
Sbjct: 165 RILDKNQRASLHSA 178


>gi|148762948 pseudouridylate synthase 7 homolog (S.
           cerevisiae)-like [Homo sapiens]
          Length = 701

 Score = 26.6 bits (57), Expect = 4.6
 Identities = 17/74 (22%), Positives = 37/74 (50%)

Query: 7   AEETAFVVDEVSNIVKEAIESAIGGNAYQHSKVNQWTTNVVEQTLSQLTKLGKPFKYIVT 66
           +E+   +VD  S   ++A   +   +   H  +N +  +V E+ LS+   +G P ++ + 
Sbjct: 105 SEKEDTIVDGTSKCEEKADVLSSFLDEKTHELLNNFACDVREKWLSKTELIGLPPEFSIG 164

Query: 67  CVIMQKNGAGLHTA 80
            ++ +   A LH+A
Sbjct: 165 RILDKNQRASLHSA 178


>gi|148762961 pseudouridylate synthase 7 homolog (S.
           cerevisiae)-like [Homo sapiens]
          Length = 701

 Score = 26.6 bits (57), Expect = 4.6
 Identities = 17/74 (22%), Positives = 37/74 (50%)

Query: 7   AEETAFVVDEVSNIVKEAIESAIGGNAYQHSKVNQWTTNVVEQTLSQLTKLGKPFKYIVT 66
           +E+   +VD  S   ++A   +   +   H  +N +  +V E+ LS+   +G P ++ + 
Sbjct: 105 SEKEDTIVDGTSKCEEKADVLSSFLDEKTHELLNNFACDVREKWLSKTELIGLPPEFSIG 164

Query: 67  CVIMQKNGAGLHTA 80
            ++ +   A LH+A
Sbjct: 165 RILDKNQRASLHSA 178


>gi|19923626 apolipoprotein L4 isoform 1 [Homo sapiens]
          Length = 348

 Score = 26.6 bits (57), Expect = 4.6
 Identities = 14/56 (25%), Positives = 29/56 (51%), Gaps = 1/56 (1%)

Query: 7   AEETAFVVDEVSNIVKEAIESAIGGNAYQHSKVNQWTTNVVEQTLSQLTKLGKPFK 62
           A     VV +V N+V+++++   G  +     + QW    +E+ L++LT + +  K
Sbjct: 292 ATSGVLVVLDVVNLVQDSLDLHKGAKSESAESLRQWAQE-LEENLNELTHIHQSLK 346


>gi|22035657 apolipoprotein L4 isoform 2 precursor [Homo sapiens]
          Length = 351

 Score = 26.6 bits (57), Expect = 4.6
 Identities = 14/56 (25%), Positives = 29/56 (51%), Gaps = 1/56 (1%)

Query: 7   AEETAFVVDEVSNIVKEAIESAIGGNAYQHSKVNQWTTNVVEQTLSQLTKLGKPFK 62
           A     VV +V N+V+++++   G  +     + QW    +E+ L++LT + +  K
Sbjct: 295 ATSGVLVVLDVVNLVQDSLDLHKGAKSESAESLRQWAQE-LEENLNELTHIHQSLK 349


>gi|153252003 sarcomeric mitochondrial creatine kinase precursor
           [Homo sapiens]
          Length = 419

 Score = 26.2 bits (56), Expect = 6.0
 Identities = 14/58 (24%), Positives = 28/58 (48%)

Query: 16  EVSNIVKEAIESAIGGNAYQHSKVNQWTTNVVEQTLSQLTKLGKPFKYIVTCVIMQKN 73
           EV N+   A+E   G  A ++ K+++ T    ++ +       KP   ++TC  M ++
Sbjct: 187 EVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLIDDHFLFDKPVSPLLTCAGMARD 244


>gi|153251984 sarcomeric mitochondrial creatine kinase precursor
           [Homo sapiens]
          Length = 419

 Score = 26.2 bits (56), Expect = 6.0
 Identities = 14/58 (24%), Positives = 28/58 (48%)

Query: 16  EVSNIVKEAIESAIGGNAYQHSKVNQWTTNVVEQTLSQLTKLGKPFKYIVTCVIMQKN 73
           EV N+   A+E   G  A ++ K+++ T    ++ +       KP   ++TC  M ++
Sbjct: 187 EVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLIDDHFLFDKPVSPLLTCAGMARD 244


>gi|153251982 sarcomeric mitochondrial creatine kinase precursor
           [Homo sapiens]
          Length = 419

 Score = 26.2 bits (56), Expect = 6.0
 Identities = 14/58 (24%), Positives = 28/58 (48%)

Query: 16  EVSNIVKEAIESAIGGNAYQHSKVNQWTTNVVEQTLSQLTKLGKPFKYIVTCVIMQKN 73
           EV N+   A+E   G  A ++ K+++ T    ++ +       KP   ++TC  M ++
Sbjct: 187 EVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLIDDHFLFDKPVSPLLTCAGMARD 244


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.127    0.381 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,814,344
Number of Sequences: 37866
Number of extensions: 129892
Number of successful extensions: 311
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 285
Number of HSP's gapped (non-prelim): 21
length of query: 113
length of database: 18,247,518
effective HSP length: 83
effective length of query: 30
effective length of database: 15,104,640
effective search space: 453139200
effective search space used: 453139200
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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