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Search of human proteins with 56786144
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|56786144 dual specificity phosphatase 23 [Homo sapiens]
(150 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|56786144 dual specificity phosphatase 23 [Homo sapiens] 311 1e-85
gi|116008458 CDC14 homolog B isoform 3 [Homo sapiens] 63 8e-11
gi|4502699 CDC14 homolog B isoform 1 [Homo sapiens] 63 8e-11
gi|15451936 CDC14 homolog B isoform 2 [Homo sapiens] 63 8e-11
gi|15451933 CDC14 homolog A isoform 3 [Homo sapiens] 59 1e-09
gi|15451929 CDC14 homolog A isoform 1 [Homo sapiens] 59 1e-09
gi|15451931 CDC14 homolog A isoform 2 [Homo sapiens] 59 1e-09
gi|30089952 protein tyrosine phosphatase domain containing 1 pro... 52 2e-07
gi|30089950 protein tyrosine phosphatase domain containing 1 pro... 52 2e-07
gi|166235184 KIAA1274 [Homo sapiens] 49 2e-06
gi|134142828 RNA guanylyltransferase and 5'-phosphatase [Homo sa... 48 3e-06
gi|38372911 dual specificity phosphatase 16 [Homo sapiens] 45 2e-05
gi|108802609 protein tyrosine phosphatase, non-receptor type 20 ... 44 4e-05
gi|108802611 protein tyrosine phosphatase, non-receptor type 20 ... 44 4e-05
gi|109138573 protein tyrosine phosphatase, non-receptor type 20A... 44 4e-05
gi|109138565 protein tyrosine phosphatase, non-receptor type 20A... 44 4e-05
gi|109138563 protein tyrosine phosphatase, non-receptor type 20A... 44 4e-05
gi|109138561 protein tyrosine phosphatase, non-receptor type 20A... 44 4e-05
gi|109138557 protein tyrosine phosphatase, non-receptor type 20A... 44 4e-05
gi|108802617 protein tyrosine phosphatase, non-receptor type 20 ... 44 4e-05
gi|108802607 protein tyrosine phosphatase, non-receptor type 20 ... 44 4e-05
gi|108802604 protein tyrosine phosphatase, non-receptor type 20 ... 44 4e-05
gi|153281158 dual specificity phosphatase 8 [Homo sapiens] 44 4e-05
gi|6005956 dual specificity phosphatase 12 [Homo sapiens] 43 9e-05
gi|4503421 dual specificity phosphatase 9 [Homo sapiens] 42 1e-04
gi|148224884 protein tyrosine phosphatase, mitochondrial 1 isofo... 42 2e-04
gi|14589856 protein tyrosine phosphatase type IVA, member 3 isof... 42 2e-04
gi|75750526 dual specificity phosphatase 28 [Homo sapiens] 42 3e-04
gi|5729993 protein tyrosine phosphatase, receptor type, E isofor... 40 7e-04
gi|18860859 protein tyrosine phosphatase, receptor type, E isofo... 40 7e-04
>gi|56786144 dual specificity phosphatase 23 [Homo sapiens]
Length = 150
Score = 311 bits (798), Expect = 1e-85
Identities = 150/150 (100%), Positives = 150/150 (100%)
Query: 1 MGVQPPNFSWVLPGRLAGLALPRLPAHYQFLLDLGVRHLVSLTERGPPHSDSCPGLTLHR 60
MGVQPPNFSWVLPGRLAGLALPRLPAHYQFLLDLGVRHLVSLTERGPPHSDSCPGLTLHR
Sbjct: 1 MGVQPPNFSWVLPGRLAGLALPRLPAHYQFLLDLGVRHLVSLTERGPPHSDSCPGLTLHR 60
Query: 61 LRIPDFCPPAPDQIDRFVQIVDEANARGEAVGVHCALGFGRTGTMLACYLVKERGLAAGD 120
LRIPDFCPPAPDQIDRFVQIVDEANARGEAVGVHCALGFGRTGTMLACYLVKERGLAAGD
Sbjct: 61 LRIPDFCPPAPDQIDRFVQIVDEANARGEAVGVHCALGFGRTGTMLACYLVKERGLAAGD 120
Query: 121 AIAEIRRLRPGSIETYEQEKAVFQFYQRTK 150
AIAEIRRLRPGSIETYEQEKAVFQFYQRTK
Sbjct: 121 AIAEIRRLRPGSIETYEQEKAVFQFYQRTK 150
>gi|116008458 CDC14 homolog B isoform 3 [Homo sapiens]
Length = 461
Score = 63.2 bits (152), Expect = 8e-11
Identities = 46/154 (29%), Positives = 73/154 (47%), Gaps = 21/154 (13%)
Query: 7 NFSWVLPGRLAGLALP----RLPAHY---------QFLLDLGVRHLVSLTER---GPPHS 50
+ +W++P R P RL + Y Q+ + V ++ L +R +
Sbjct: 178 DLNWIIPDRFIAFCGPHSRARLESGYHQHSPETYIQYFKNHNVTTIIRLNKRMYDAKRFT 237
Query: 51 DSCPGLTLHRLRIPDFCPPAPDQIDRFVQIVDEANARGEAVGVHCALGFGRTGTMLACYL 110
D+ G H L D P + F+ I + NA G A+ VHC G GRTGT++ACY+
Sbjct: 238 DA--GFDHHDLFFADGSTPTDAIVKEFLDICE--NAEG-AIAVHCKAGLGRTGTLIACYI 292
Query: 111 VKERGLAAGDAIAEIRRLRPGSIETYEQEKAVFQ 144
+K + A + IA +R RPGS+ +Q+ V +
Sbjct: 293 MKHYRMTAAETIAWVRICRPGSVIGPQQQFLVMK 326
>gi|4502699 CDC14 homolog B isoform 1 [Homo sapiens]
Length = 459
Score = 63.2 bits (152), Expect = 8e-11
Identities = 46/154 (29%), Positives = 73/154 (47%), Gaps = 21/154 (13%)
Query: 7 NFSWVLPGRLAGLALP----RLPAHY---------QFLLDLGVRHLVSLTER---GPPHS 50
+ +W++P R P RL + Y Q+ + V ++ L +R +
Sbjct: 215 DLNWIIPDRFIAFCGPHSRARLESGYHQHSPETYIQYFKNHNVTTIIRLNKRMYDAKRFT 274
Query: 51 DSCPGLTLHRLRIPDFCPPAPDQIDRFVQIVDEANARGEAVGVHCALGFGRTGTMLACYL 110
D+ G H L D P + F+ I + NA G A+ VHC G GRTGT++ACY+
Sbjct: 275 DA--GFDHHDLFFADGSTPTDAIVKEFLDICE--NAEG-AIAVHCKAGLGRTGTLIACYI 329
Query: 111 VKERGLAAGDAIAEIRRLRPGSIETYEQEKAVFQ 144
+K + A + IA +R RPGS+ +Q+ V +
Sbjct: 330 MKHYRMTAAETIAWVRICRPGSVIGPQQQFLVMK 363
>gi|15451936 CDC14 homolog B isoform 2 [Homo sapiens]
Length = 498
Score = 63.2 bits (152), Expect = 8e-11
Identities = 46/154 (29%), Positives = 73/154 (47%), Gaps = 21/154 (13%)
Query: 7 NFSWVLPGRLAGLALP----RLPAHY---------QFLLDLGVRHLVSLTER---GPPHS 50
+ +W++P R P RL + Y Q+ + V ++ L +R +
Sbjct: 215 DLNWIIPDRFIAFCGPHSRARLESGYHQHSPETYIQYFKNHNVTTIIRLNKRMYDAKRFT 274
Query: 51 DSCPGLTLHRLRIPDFCPPAPDQIDRFVQIVDEANARGEAVGVHCALGFGRTGTMLACYL 110
D+ G H L D P + F+ I + NA G A+ VHC G GRTGT++ACY+
Sbjct: 275 DA--GFDHHDLFFADGSTPTDAIVKEFLDICE--NAEG-AIAVHCKAGLGRTGTLIACYI 329
Query: 111 VKERGLAAGDAIAEIRRLRPGSIETYEQEKAVFQ 144
+K + A + IA +R RPGS+ +Q+ V +
Sbjct: 330 MKHYRMTAAETIAWVRICRPGSVIGPQQQFLVMK 363
>gi|15451933 CDC14 homolog A isoform 3 [Homo sapiens]
Length = 383
Score = 59.3 bits (142), Expect = 1e-09
Identities = 44/147 (29%), Positives = 70/147 (47%), Gaps = 21/147 (14%)
Query: 3 VQPPNFSWVLPGRLA-------------GLALPRLPAHYQFLLDLGVRHLVSLTER---G 46
V+ +F+W++PG+ G L A++ + V +V L ++
Sbjct: 175 VENGDFNWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFKKHNVTAVVRLNKKIYEA 234
Query: 47 PPHSDSCPGLTLHRLRIPDFCPPAPDQIDRFVQIVDEANARGEAVGVHCALGFGRTGTML 106
+D+ G + L D P+ + + RF+ I + N G A+ VHC G GRTGT++
Sbjct: 235 KRFTDA--GFEHYDLFFIDGSTPSDNIVRRFLNICE--NTEG-AIAVHCKAGLGRTGTLI 289
Query: 107 ACYLVKERGLAAGDAIAEIRRLRPGSI 133
ACY++K + IA IR RPGSI
Sbjct: 290 ACYVMKHYRFTHAEIIAWIRICRPGSI 316
>gi|15451929 CDC14 homolog A isoform 1 [Homo sapiens]
Length = 594
Score = 59.3 bits (142), Expect = 1e-09
Identities = 44/147 (29%), Positives = 70/147 (47%), Gaps = 21/147 (14%)
Query: 3 VQPPNFSWVLPGRLA-------------GLALPRLPAHYQFLLDLGVRHLVSLTER---G 46
V+ +F+W++PG+ G L A++ + V +V L ++
Sbjct: 175 VENGDFNWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFKKHNVTAVVRLNKKIYEA 234
Query: 47 PPHSDSCPGLTLHRLRIPDFCPPAPDQIDRFVQIVDEANARGEAVGVHCALGFGRTGTML 106
+D+ G + L D P+ + + RF+ I + N G A+ VHC G GRTGT++
Sbjct: 235 KRFTDA--GFEHYDLFFIDGSTPSDNIVRRFLNICE--NTEG-AIAVHCKAGLGRTGTLI 289
Query: 107 ACYLVKERGLAAGDAIAEIRRLRPGSI 133
ACY++K + IA IR RPGSI
Sbjct: 290 ACYVMKHYRFTHAEIIAWIRICRPGSI 316
>gi|15451931 CDC14 homolog A isoform 2 [Homo sapiens]
Length = 623
Score = 59.3 bits (142), Expect = 1e-09
Identities = 44/147 (29%), Positives = 70/147 (47%), Gaps = 21/147 (14%)
Query: 3 VQPPNFSWVLPGRLA-------------GLALPRLPAHYQFLLDLGVRHLVSLTER---G 46
V+ +F+W++PG+ G L A++ + V +V L ++
Sbjct: 175 VENGDFNWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFKKHNVTAVVRLNKKIYEA 234
Query: 47 PPHSDSCPGLTLHRLRIPDFCPPAPDQIDRFVQIVDEANARGEAVGVHCALGFGRTGTML 106
+D+ G + L D P+ + + RF+ I + N G A+ VHC G GRTGT++
Sbjct: 235 KRFTDA--GFEHYDLFFIDGSTPSDNIVRRFLNICE--NTEG-AIAVHCKAGLGRTGTLI 289
Query: 107 ACYLVKERGLAAGDAIAEIRRLRPGSI 133
ACY++K + IA IR RPGSI
Sbjct: 290 ACYVMKHYRFTHAEIIAWIRICRPGSI 316
>gi|30089952 protein tyrosine phosphatase domain containing 1
protein isoform 1 [Homo sapiens]
Length = 806
Score = 52.0 bits (123), Expect = 2e-07
Identities = 26/57 (45%), Positives = 33/57 (57%)
Query: 91 VGVHCALGFGRTGTMLACYLVKERGLAAGDAIAEIRRLRPGSIETYEQEKAVFQFYQ 147
V +HC G GRTG ++ACYLV + A AI +R RP SI+T Q V +F Q
Sbjct: 238 VAIHCHAGLGRTGVLIACYLVFATRMTADQAIIFVRAKRPNSIQTRGQLLCVREFTQ 294
>gi|30089950 protein tyrosine phosphatase domain containing 1
protein isoform 2 [Homo sapiens]
Length = 754
Score = 52.0 bits (123), Expect = 2e-07
Identities = 26/57 (45%), Positives = 33/57 (57%)
Query: 91 VGVHCALGFGRTGTMLACYLVKERGLAAGDAIAEIRRLRPGSIETYEQEKAVFQFYQ 147
V +HC G GRTG ++ACYLV + A AI +R RP SI+T Q V +F Q
Sbjct: 186 VAIHCHAGLGRTGVLIACYLVFATRMTADQAIIFVRAKRPNSIQTRGQLLCVREFTQ 242
>gi|166235184 KIAA1274 [Homo sapiens]
Length = 856
Score = 48.9 bits (115), Expect = 2e-06
Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 8/84 (9%)
Query: 25 PAHYQFLLDLGVRHLVSLTERGPPHSDSCPGLTLHRLRIPDFCPPAPDQIDRFVQIVDEA 84
P Y+F L ++ + S H +CPGLT HR+ +PDFC P + D+ ++ + A
Sbjct: 595 PLTYRFQTCLTMQEVFS------QHRRACPGLTYHRIPMPDFCAPREEDFDQLLEALRAA 648
Query: 85 NARGEAVG--VHCALGFGRTGTML 106
++ G C G GRT T +
Sbjct: 649 LSKDPGTGFVFSCLSGQGRTTTAM 672
Score = 31.6 bits (70), Expect = 0.26
Identities = 24/95 (25%), Positives = 40/95 (42%), Gaps = 11/95 (11%)
Query: 54 PGLTLHRLRIPDFCPPAPDQIDRFVQIVDE---------ANARGEAVGVHCALGFGRT-- 102
P HRL +P+ P Q+D FV ++ E A+ A+ C +G GRT
Sbjct: 262 PTYRYHRLPLPEQGSPLEAQLDAFVSVLRETPSLLQLRDAHGPPPALVFSCQMGVGRTNL 321
Query: 103 GTMLACYLVKERGLAAGDAIAEIRRLRPGSIETYE 137
G +L ++ R A + +P +E ++
Sbjct: 322 GMVLGTLILLHRSGTTSQPEAAPTQAKPLPMEQFQ 356
>gi|134142828 RNA guanylyltransferase and 5'-phosphatase [Homo
sapiens]
Length = 597
Score = 48.1 bits (113), Expect = 3e-06
Identities = 24/80 (30%), Positives = 42/80 (52%), Gaps = 2/80 (2%)
Query: 69 PAPDQIDRFVQIVDEANARG--EAVGVHCALGFGRTGTMLACYLVKERGLAAGDAIAEIR 126
P + + F+++ + N R E +GVHC GF RTG ++ +LV++ + A+A
Sbjct: 98 PTTENTETFIRLCERFNERNPPELIGVHCTHGFNRTGFLICAFLVEKMDWSIEAAVATFA 157
Query: 127 RLRPGSIETYEQEKAVFQFY 146
+ RP I + K +F+ Y
Sbjct: 158 QARPPGIYKGDYLKELFRRY 177
>gi|38372911 dual specificity phosphatase 16 [Homo sapiens]
Length = 665
Score = 45.1 bits (105), Expect = 2e-05
Identities = 25/88 (28%), Positives = 42/88 (47%), Gaps = 7/88 (7%)
Query: 50 SDSCPGLTL----HRLRIP---DFCPPAPDQIDRFVQIVDEANARGEAVGVHCALGFGRT 102
S++CP H LR+P FC +D+ V +++A A V VHC G R+
Sbjct: 192 SNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKASNGCVLVHCLAGISRS 251
Query: 103 GTMLACYLVKERGLAAGDAIAEIRRLRP 130
T+ Y++K ++ +A ++ RP
Sbjct: 252 ATIAIAYIMKRMDMSLDEAYRFVKEKRP 279
>gi|108802609 protein tyrosine phosphatase, non-receptor type 20
isoform 4 [Homo sapiens]
Length = 269
Score = 44.3 bits (103), Expect = 4e-05
Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 6/76 (7%)
Query: 68 PPAPDQIDRFVQIVDEANARGEAVGVHCALGFGRTGTMLA-----CYLVKERGLAAGDAI 122
P + D ++++ +++ G V VHC+ G GRTG L C +VK D +
Sbjct: 176 PASADSFIKYIRYARKSHLTGPMV-VHCSAGIGRTGVFLCVDVVFCAIVKNCSFNIMDIV 234
Query: 123 AEIRRLRPGSIETYEQ 138
A++R R G ++T EQ
Sbjct: 235 AQMREQRSGMVQTKEQ 250
>gi|108802611 protein tyrosine phosphatase, non-receptor type 20
isoform 5 [Homo sapiens]
Length = 228
Score = 44.3 bits (103), Expect = 4e-05
Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 6/76 (7%)
Query: 68 PPAPDQIDRFVQIVDEANARGEAVGVHCALGFGRTGTMLA-----CYLVKERGLAAGDAI 122
P + D ++++ +++ G V VHC+ G GRTG L C +VK D +
Sbjct: 135 PASADSFIKYIRYARKSHLTGPMV-VHCSAGIGRTGVFLCVDVVFCAIVKNCSFNIMDIV 193
Query: 123 AEIRRLRPGSIETYEQ 138
A++R R G ++T EQ
Sbjct: 194 AQMREQRSGMVQTKEQ 209
>gi|109138573 protein tyrosine phosphatase, non-receptor type 20A
isoform 8 [Homo sapiens]
Length = 339
Score = 44.3 bits (103), Expect = 4e-05
Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 6/76 (7%)
Query: 68 PPAPDQIDRFVQIVDEANARGEAVGVHCALGFGRTGTMLA-----CYLVKERGLAAGDAI 122
P + D ++++ +++ G V VHC+ G GRTG L C +VK D +
Sbjct: 246 PASADSFIKYIRYARKSHLTGPMV-VHCSAGIGRTGVFLCVDVVFCAIVKNCSFNIMDIV 304
Query: 123 AEIRRLRPGSIETYEQ 138
A++R R G ++T EQ
Sbjct: 305 AQMREQRSGMVQTKEQ 320
>gi|109138565 protein tyrosine phosphatase, non-receptor type 20A
isoform 5 [Homo sapiens]
Length = 228
Score = 44.3 bits (103), Expect = 4e-05
Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 6/76 (7%)
Query: 68 PPAPDQIDRFVQIVDEANARGEAVGVHCALGFGRTGTMLA-----CYLVKERGLAAGDAI 122
P + D ++++ +++ G V VHC+ G GRTG L C +VK D +
Sbjct: 135 PASADSFIKYIRYARKSHLTGPMV-VHCSAGIGRTGVFLCVDVVFCAIVKNCSFNIMDIV 193
Query: 123 AEIRRLRPGSIETYEQ 138
A++R R G ++T EQ
Sbjct: 194 AQMREQRSGMVQTKEQ 209
>gi|109138563 protein tyrosine phosphatase, non-receptor type 20A
isoform 4 [Homo sapiens]
Length = 269
Score = 44.3 bits (103), Expect = 4e-05
Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 6/76 (7%)
Query: 68 PPAPDQIDRFVQIVDEANARGEAVGVHCALGFGRTGTMLA-----CYLVKERGLAAGDAI 122
P + D ++++ +++ G V VHC+ G GRTG L C +VK D +
Sbjct: 176 PASADSFIKYIRYARKSHLTGPMV-VHCSAGIGRTGVFLCVDVVFCAIVKNCSFNIMDIV 234
Query: 123 AEIRRLRPGSIETYEQ 138
A++R R G ++T EQ
Sbjct: 235 AQMREQRSGMVQTKEQ 250
>gi|109138561 protein tyrosine phosphatase, non-receptor type 20A
isoform 3 [Homo sapiens]
Length = 411
Score = 44.3 bits (103), Expect = 4e-05
Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 6/76 (7%)
Query: 68 PPAPDQIDRFVQIVDEANARGEAVGVHCALGFGRTGTMLA-----CYLVKERGLAAGDAI 122
P + D ++++ +++ G V VHC+ G GRTG L C +VK D +
Sbjct: 318 PASADSFIKYIRYARKSHLTGPMV-VHCSAGIGRTGVFLCVDVVFCAIVKNCSFNIMDIV 376
Query: 123 AEIRRLRPGSIETYEQ 138
A++R R G ++T EQ
Sbjct: 377 AQMREQRSGMVQTKEQ 392
>gi|109138557 protein tyrosine phosphatase, non-receptor type 20A
isoform 1 [Homo sapiens]
Length = 420
Score = 44.3 bits (103), Expect = 4e-05
Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 6/76 (7%)
Query: 68 PPAPDQIDRFVQIVDEANARGEAVGVHCALGFGRTGTMLA-----CYLVKERGLAAGDAI 122
P + D ++++ +++ G V VHC+ G GRTG L C +VK D +
Sbjct: 327 PASADSFIKYIRYARKSHLTGPMV-VHCSAGIGRTGVFLCVDVVFCAIVKNCSFNIMDIV 385
Query: 123 AEIRRLRPGSIETYEQ 138
A++R R G ++T EQ
Sbjct: 386 AQMREQRSGMVQTKEQ 401
>gi|108802617 protein tyrosine phosphatase, non-receptor type 20
isoform 8 [Homo sapiens]
Length = 339
Score = 44.3 bits (103), Expect = 4e-05
Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 6/76 (7%)
Query: 68 PPAPDQIDRFVQIVDEANARGEAVGVHCALGFGRTGTMLA-----CYLVKERGLAAGDAI 122
P + D ++++ +++ G V VHC+ G GRTG L C +VK D +
Sbjct: 246 PASADSFIKYIRYARKSHLTGPMV-VHCSAGIGRTGVFLCVDVVFCAIVKNCSFNIMDIV 304
Query: 123 AEIRRLRPGSIETYEQ 138
A++R R G ++T EQ
Sbjct: 305 AQMREQRSGMVQTKEQ 320
>gi|108802607 protein tyrosine phosphatase, non-receptor type 20
isoform 3 [Homo sapiens]
Length = 411
Score = 44.3 bits (103), Expect = 4e-05
Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 6/76 (7%)
Query: 68 PPAPDQIDRFVQIVDEANARGEAVGVHCALGFGRTGTMLA-----CYLVKERGLAAGDAI 122
P + D ++++ +++ G V VHC+ G GRTG L C +VK D +
Sbjct: 318 PASADSFIKYIRYARKSHLTGPMV-VHCSAGIGRTGVFLCVDVVFCAIVKNCSFNIMDIV 376
Query: 123 AEIRRLRPGSIETYEQ 138
A++R R G ++T EQ
Sbjct: 377 AQMREQRSGMVQTKEQ 392
>gi|108802604 protein tyrosine phosphatase, non-receptor type 20
isoform 1 [Homo sapiens]
Length = 420
Score = 44.3 bits (103), Expect = 4e-05
Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 6/76 (7%)
Query: 68 PPAPDQIDRFVQIVDEANARGEAVGVHCALGFGRTGTMLA-----CYLVKERGLAAGDAI 122
P + D ++++ +++ G V VHC+ G GRTG L C +VK D +
Sbjct: 327 PASADSFIKYIRYARKSHLTGPMV-VHCSAGIGRTGVFLCVDVVFCAIVKNCSFNIMDIV 385
Query: 123 AEIRRLRPGSIETYEQ 138
A++R R G ++T EQ
Sbjct: 386 AQMREQRSGMVQTKEQ 401
>gi|153281158 dual specificity phosphatase 8 [Homo sapiens]
Length = 625
Score = 44.3 bits (103), Expect = 4e-05
Identities = 24/88 (27%), Positives = 44/88 (50%), Gaps = 7/88 (7%)
Query: 50 SDSCPGLTL----HRLRIP---DFCPPAPDQIDRFVQIVDEANARGEAVGVHCALGFGRT 102
S+SCP +R+P ++C +D+ ++ +D+A V VHC G R+
Sbjct: 194 SNSCPKPDFICESRFMRVPINDNYCEKLLPWLDKSIEFIDKAKLSSCQVIVHCLAGISRS 253
Query: 103 GTMLACYLVKERGLAAGDAIAEIRRLRP 130
T+ Y++K G+++ DA ++ RP
Sbjct: 254 ATIAIAYIMKTMGMSSDDAYRFVKDRRP 281
>gi|6005956 dual specificity phosphatase 12 [Homo sapiens]
Length = 340
Score = 43.1 bits (100), Expect = 9e-05
Identities = 37/125 (29%), Positives = 57/125 (45%), Gaps = 9/125 (7%)
Query: 11 VLPGR-LAGLALPRLPAHYQFLLDLGVRHLVSLTERGPPHSDSCPGLT-LHRLRIPDFCP 68
V PG G A P H L + G+ ++++ P PG+ L RL +P
Sbjct: 30 VQPGLYFGGAAAVAEPDH---LREAGITAVLTVDSEEPSFKAG-PGVEDLWRLFVPALDK 85
Query: 69 PAPD---QIDRFVQIVDEANARGEAVGVHCALGFGRTGTMLACYLVKERGLAAGDAIAEI 125
P D +DR V + +A A G AV VHC G R+ ++ +L+K L A ++
Sbjct: 86 PETDLLSHLDRCVAFIGQARAEGRAVLVHCHAGVSRSVAIITAFLMKTDQLPFEKAYEKL 145
Query: 126 RRLRP 130
+ L+P
Sbjct: 146 QILKP 150
>gi|4503421 dual specificity phosphatase 9 [Homo sapiens]
Length = 384
Score = 42.4 bits (98), Expect = 1e-04
Identities = 32/121 (26%), Positives = 58/121 (47%), Gaps = 9/121 (7%)
Query: 11 VLPGRLAGLALPRLPAHYQFLLDLGVRHLVSLTERGPPHSDSCPGLTLHRLRIPDFCPPA 70
+LP G A R A+ + L LG+R+++++T P + ++ I D
Sbjct: 207 ILPNLYLGSA--RDSANLESLAKLGIRYILNVTPNLPNFFEKNGDFHYKQIPISDHWS-- 262
Query: 71 PDQIDRF----VQIVDEANARGEAVGVHCALGFGRTGTMLACYLVKERGLAAGDAIAEIR 126
+ RF ++ +DEA ++ V VHC G R+ T+ YL+++ L+ DA ++
Sbjct: 263 -QNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVK 321
Query: 127 R 127
R
Sbjct: 322 R 322
>gi|148224884 protein tyrosine phosphatase, mitochondrial 1 isoform
1 [Homo sapiens]
Length = 201
Score = 42.0 bits (97), Expect = 2e-04
Identities = 37/133 (27%), Positives = 61/133 (45%), Gaps = 14/133 (10%)
Query: 20 ALPRLPAHYQFLLDLGVRHLVSLTERGPPH-----SDSCPGLTLHRLRIPDFCP---PAP 71
ALP Q + D VR ++++ E S L + +LR+ P
Sbjct: 49 ALPLRSLTRQLVQDENVRGVITMNEEYETRFLCNSSQEWKRLGVEQLRLSTVDMTGIPTL 108
Query: 72 DQIDRFVQIVDEANARGEAVGVHCALGFGRTGTMLACYLVKERGLA---AGDAIAEIR-- 126
D + + VQ + + G+ V VHC G R+ TM+A YL++ + A AIA+IR
Sbjct: 109 DNLQKGVQFALKYQSLGQCVYVHCKAGRSRSATMVAAYLIQVHKWSPEEAVRAIAKIRSY 168
Query: 127 -RLRPGSIETYEQ 138
+RPG ++ ++
Sbjct: 169 IHIRPGQLDVLKE 181
>gi|14589856 protein tyrosine phosphatase type IVA, member 3 isoform
1 [Homo sapiens]
Length = 173
Score = 42.0 bits (97), Expect = 2e-04
Identities = 27/83 (32%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
Query: 55 GLTLHRLRIPDFCPPAPDQIDRFVQIVDE--ANARGEAVGVHCALGFGRTGTMLACYLVK 112
G+T+ D PP ++ ++ +V A G V VHC G GR ++A L+
Sbjct: 62 GITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI- 120
Query: 113 ERGLAAGDAIAEIRRLRPGSIET 135
E G+ DAI IR+ R G+I +
Sbjct: 121 ESGMKYEDAIQFIRQKRRGAINS 143
>gi|75750526 dual specificity phosphatase 28 [Homo sapiens]
Length = 176
Score = 41.6 bits (96), Expect = 3e-04
Identities = 36/129 (27%), Positives = 55/129 (42%), Gaps = 9/129 (6%)
Query: 5 PPNFSWVLPGRLAGLALPRLPAHYQFLLDLGVRHLVSLTERGPPHSDSCPGLTLHRLRIP 64
PP V P G A R + L GV V+++ + P PG+ LR+P
Sbjct: 16 PPPLVRVAPSLFLGSA--RAAGAEEQLARAGVTLCVNVSRQQP--GPRAPGVA--ELRVP 69
Query: 65 DFCPPAPD---QIDRFVQIVDEANARGEAVGVHCALGFGRTGTMLACYLVKERGLAAGDA 121
F PA D ++ ++ A G A V+C G R+ + YL++ RGL+ A
Sbjct: 70 VFDDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSLAKA 129
Query: 122 IAEIRRLRP 130
++ RP
Sbjct: 130 FQMVKSARP 138
>gi|5729993 protein tyrosine phosphatase, receptor type, E isoform 1
precursor [Homo sapiens]
Length = 700
Score = 40.0 bits (92), Expect = 7e-04
Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 5/62 (8%)
Query: 91 VGVHCALGFGRTGTMLACYLVKERGLAAG-----DAIAEIRRLRPGSIETYEQEKAVFQF 145
+ VHC+ G GRTGT +A + ER A G A+ +R RP ++T EQ + ++
Sbjct: 626 ITVHCSAGAGRTGTFIALSNILERVKAEGLLDVFQAVKSLRLQRPHMVQTLEQYEFCYKV 685
Query: 146 YQ 147
Q
Sbjct: 686 VQ 687
Score = 36.6 bits (83), Expect = 0.008
Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 7/94 (7%)
Query: 58 LHRLRIPDFCPP-APDQIDRFVQIVDEAN-ARGEAVGVHCALGFGRTGTMLA-----CYL 110
LH PDF P P + +F++ V N + VHC+ G GRTGT + +
Sbjct: 296 LHFTSWPDFGVPFTPIGMLKFLKKVKTLNPVHAGPIVVHCSAGVGRTGTFIVIDAMMAMM 355
Query: 111 VKERGLAAGDAIAEIRRLRPGSIETYEQEKAVFQ 144
E+ + + ++ IR RP ++T Q ++Q
Sbjct: 356 HAEQKVDVFEFVSRIRNQRPQMVQTDMQYTFIYQ 389
>gi|18860859 protein tyrosine phosphatase, receptor type, E isoform
2 [Homo sapiens]
Length = 642
Score = 40.0 bits (92), Expect = 7e-04
Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 5/62 (8%)
Query: 91 VGVHCALGFGRTGTMLACYLVKERGLAAG-----DAIAEIRRLRPGSIETYEQEKAVFQF 145
+ VHC+ G GRTGT +A + ER A G A+ +R RP ++T EQ + ++
Sbjct: 568 ITVHCSAGAGRTGTFIALSNILERVKAEGLLDVFQAVKSLRLQRPHMVQTLEQYEFCYKV 627
Query: 146 YQ 147
Q
Sbjct: 628 VQ 629
Score = 36.6 bits (83), Expect = 0.008
Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 7/94 (7%)
Query: 58 LHRLRIPDFCPP-APDQIDRFVQIVDEAN-ARGEAVGVHCALGFGRTGTMLA-----CYL 110
LH PDF P P + +F++ V N + VHC+ G GRTGT + +
Sbjct: 238 LHFTSWPDFGVPFTPIGMLKFLKKVKTLNPVHAGPIVVHCSAGVGRTGTFIVIDAMMAMM 297
Query: 111 VKERGLAAGDAIAEIRRLRPGSIETYEQEKAVFQ 144
E+ + + ++ IR RP ++T Q ++Q
Sbjct: 298 HAEQKVDVFEFVSRIRNQRPQMVQTDMQYTFIYQ 331
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.143 0.450
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,712,167
Number of Sequences: 37866
Number of extensions: 303271
Number of successful extensions: 1078
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 103
Number of HSP's successfully gapped in prelim test: 60
Number of HSP's that attempted gapping in prelim test: 941
Number of HSP's gapped (non-prelim): 193
length of query: 150
length of database: 18,247,518
effective HSP length: 93
effective length of query: 57
effective length of database: 14,725,980
effective search space: 839380860
effective search space used: 839380860
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.