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Search of human proteins with 56699403
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|56699403 solute carrier family 25, member 25 isoform b [Homo
sapiens]
(503 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239755174 PREDICTED: similar to solute carrier family 25, mem... 1007 0.0
gi|56699403 solute carrier family 25, member 25 isoform b [Homo ... 1007 0.0
gi|239755176 PREDICTED: similar to solute carrier family 25, mem... 832 0.0
gi|56699401 solute carrier family 25, member 25 isoform a [Homo ... 832 0.0
gi|56699407 solute carrier family 25, member 25 isoform c [Homo ... 830 0.0
gi|56699405 solute carrier family 25, member 25 isoform d [Homo ... 731 0.0
gi|48476342 solute carrier family 25, member 23 [Homo sapiens] 631 0.0
gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo ... 609 e-174
gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo s... 603 e-172
gi|149274607 solute carrier family 25, member 41 [Homo sapiens] 324 1e-88
gi|60460887 solute carrier family 25, member 42 [Homo sapiens] 176 4e-44
gi|27544933 solute carrier family 25, member 16 [Homo sapiens] 171 1e-42
gi|21687151 mitochondrial solute carrier protein [Homo sapiens] 125 1e-28
gi|13775208 solute carrier family 25 (mitochondrial carrier; ade... 116 5e-26
gi|156071459 solute carrier family 25, member 5 [Homo sapiens] 115 7e-26
gi|156071462 solute carrier family 25, member A6 [Homo sapiens] 115 1e-25
gi|186928856 solute carrier family 25, member 19 [Homo sapiens] 115 1e-25
gi|186928860 solute carrier family 25, member 19 [Homo sapiens] 115 1e-25
gi|186928858 solute carrier family 25, member 19 [Homo sapiens] 115 1e-25
gi|21314739 solute carrier family 25, member 32 [Homo sapiens] 113 4e-25
gi|55749577 solute carrier family 25 (mitochondrial carrier; ade... 113 5e-25
gi|157388989 solute carrier family 25, member 36 isoform a [Homo... 108 9e-24
gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Ho... 106 6e-23
gi|13259543 solute carrier family 25, member 14 isoform UCP5S [H... 106 6e-23
gi|157388991 solute carrier family 25, member 36 isoform b [Homo... 105 1e-22
gi|14150082 mitochondrial carrier protein MGC4399 [Homo sapiens] 102 1e-21
gi|58197562 solute carrier family 25, member 30 [Homo sapiens] 100 5e-21
gi|82775373 solute carrier family 25, member 37 [Homo sapiens] 93 5e-19
gi|45237193 solute carrier family 25, member 44 isoform 1 [Homo ... 93 6e-19
gi|149274643 solute carrier family 25, member 28 [Homo sapiens] 92 1e-18
>gi|239755174 PREDICTED: similar to solute carrier family 25, member
25 isoform 1 [Homo sapiens]
Length = 503
Score = 1007 bits (2604), Expect = 0.0
Identities = 503/503 (100%), Positives = 503/503 (100%)
Query: 1 MVSSVLCRCVASPPPDAAATAASSSASSPASVGDPCGGAICGGPDHRLRLWRLFQTLDVN 60
MVSSVLCRCVASPPPDAAATAASSSASSPASVGDPCGGAICGGPDHRLRLWRLFQTLDVN
Sbjct: 1 MVSSVLCRCVASPPPDAAATAASSSASSPASVGDPCGGAICGGPDHRLRLWRLFQTLDVN 60
Query: 61 RDGGLCVNDLAVGLRRLGLHRTEGELQKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLV 120
RDGGLCVNDLAVGLRRLGLHRTEGELQKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLV
Sbjct: 61 RDGGLCVNDLAVGLRRLGLHRTEGELQKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLV 120
Query: 121 FKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLH 180
FKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLH
Sbjct: 121 FKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLH 180
Query: 181 PVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAP 240
PVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAP
Sbjct: 181 PVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAP 240
Query: 241 LDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQ 300
LDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQ
Sbjct: 241 LDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQ 300
Query: 301 IKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRI 360
IKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRI
Sbjct: 301 IKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRI 360
Query: 361 LAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTM 420
LAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTM
Sbjct: 361 LAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTM 420
Query: 421 SSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKV 480
SSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKV
Sbjct: 421 SSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKV 480
Query: 481 IPAVSISYVVYENLKITLGVQSR 503
IPAVSISYVVYENLKITLGVQSR
Sbjct: 481 IPAVSISYVVYENLKITLGVQSR 503
>gi|56699403 solute carrier family 25, member 25 isoform b [Homo
sapiens]
Length = 503
Score = 1007 bits (2604), Expect = 0.0
Identities = 503/503 (100%), Positives = 503/503 (100%)
Query: 1 MVSSVLCRCVASPPPDAAATAASSSASSPASVGDPCGGAICGGPDHRLRLWRLFQTLDVN 60
MVSSVLCRCVASPPPDAAATAASSSASSPASVGDPCGGAICGGPDHRLRLWRLFQTLDVN
Sbjct: 1 MVSSVLCRCVASPPPDAAATAASSSASSPASVGDPCGGAICGGPDHRLRLWRLFQTLDVN 60
Query: 61 RDGGLCVNDLAVGLRRLGLHRTEGELQKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLV 120
RDGGLCVNDLAVGLRRLGLHRTEGELQKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLV
Sbjct: 61 RDGGLCVNDLAVGLRRLGLHRTEGELQKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLV 120
Query: 121 FKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLH 180
FKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLH
Sbjct: 121 FKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLH 180
Query: 181 PVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAP 240
PVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAP
Sbjct: 181 PVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAP 240
Query: 241 LDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQ 300
LDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQ
Sbjct: 241 LDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQ 300
Query: 301 IKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRI 360
IKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRI
Sbjct: 301 IKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRI 360
Query: 361 LAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTM 420
LAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTM
Sbjct: 361 LAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTM 420
Query: 421 SSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKV 480
SSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKV
Sbjct: 421 SSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKV 480
Query: 481 IPAVSISYVVYENLKITLGVQSR 503
IPAVSISYVVYENLKITLGVQSR
Sbjct: 481 IPAVSISYVVYENLKITLGVQSR 503
>gi|239755176 PREDICTED: similar to solute carrier family 25, member
25 isoform 2 [Homo sapiens]
Length = 469
Score = 832 bits (2149), Expect = 0.0
Identities = 417/417 (100%), Positives = 417/417 (100%)
Query: 87 QKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGV 146
QKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGV
Sbjct: 53 QKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGV 112
Query: 147 KISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTV 206
KISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTV
Sbjct: 113 KISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTV 172
Query: 207 PDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQ 266
PDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQ
Sbjct: 173 PDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQ 232
Query: 267 MIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGA 326
MIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGA
Sbjct: 233 MIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGA 292
Query: 327 IAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGI 386
IAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGI
Sbjct: 293 IAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGI 352
Query: 387 DLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIE 446
DLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIE
Sbjct: 353 DLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIE 412
Query: 447 GAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 503
GAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR
Sbjct: 413 GAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 469
Score = 39.7 bits (91), Expect = 0.006
Identities = 20/65 (30%), Positives = 38/65 (58%)
Query: 45 DHRLRLWRLFQTLDVNRDGGLCVNDLAVGLRRLGLHRTEGELQKIVQAGDKDLDGQLDFE 104
DH +L +F++LD DG + ++ LR LG+ +E + +KI+++ DK+ +D+
Sbjct: 78 DHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWN 137
Query: 105 EFVHY 109
E+ Y
Sbjct: 138 EWRDY 142
>gi|56699401 solute carrier family 25, member 25 isoform a [Homo
sapiens]
Length = 469
Score = 832 bits (2149), Expect = 0.0
Identities = 417/417 (100%), Positives = 417/417 (100%)
Query: 87 QKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGV 146
QKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGV
Sbjct: 53 QKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGV 112
Query: 147 KISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTV 206
KISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTV
Sbjct: 113 KISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTV 172
Query: 207 PDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQ 266
PDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQ
Sbjct: 173 PDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQ 232
Query: 267 MIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGA 326
MIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGA
Sbjct: 233 MIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGA 292
Query: 327 IAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGI 386
IAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGI
Sbjct: 293 IAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGI 352
Query: 387 DLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIE 446
DLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIE
Sbjct: 353 DLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIE 412
Query: 447 GAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 503
GAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR
Sbjct: 413 GAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 469
Score = 39.7 bits (91), Expect = 0.006
Identities = 20/65 (30%), Positives = 38/65 (58%)
Query: 45 DHRLRLWRLFQTLDVNRDGGLCVNDLAVGLRRLGLHRTEGELQKIVQAGDKDLDGQLDFE 104
DH +L +F++LD DG + ++ LR LG+ +E + +KI+++ DK+ +D+
Sbjct: 78 DHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWN 137
Query: 105 EFVHY 109
E+ Y
Sbjct: 138 EWRDY 142
>gi|56699407 solute carrier family 25, member 25 isoform c [Homo
sapiens]
Length = 489
Score = 830 bits (2145), Expect = 0.0
Identities = 416/417 (99%), Positives = 417/417 (100%)
Query: 87 QKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGV 146
+KIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGV
Sbjct: 73 KKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGV 132
Query: 147 KISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTV 206
KISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTV
Sbjct: 133 KISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTV 192
Query: 207 PDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQ 266
PDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQ
Sbjct: 193 PDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQ 252
Query: 267 MIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGA 326
MIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGA
Sbjct: 253 MIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGA 312
Query: 327 IAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGI 386
IAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGI
Sbjct: 313 IAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGI 372
Query: 387 DLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIE 446
DLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIE
Sbjct: 373 DLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIE 432
Query: 447 GAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 503
GAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR
Sbjct: 433 GAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 489
Score = 39.7 bits (91), Expect = 0.006
Identities = 20/65 (30%), Positives = 38/65 (58%)
Query: 45 DHRLRLWRLFQTLDVNRDGGLCVNDLAVGLRRLGLHRTEGELQKIVQAGDKDLDGQLDFE 104
DH +L +F++LD DG + ++ LR LG+ +E + +KI+++ DK+ +D+
Sbjct: 98 DHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWN 157
Query: 105 EFVHY 109
E+ Y
Sbjct: 158 EWRDY 162
>gi|56699405 solute carrier family 25, member 25 isoform d [Homo
sapiens]
Length = 366
Score = 731 bits (1886), Expect = 0.0
Identities = 366/366 (100%), Positives = 366/366 (100%)
Query: 138 MQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTI 197
MQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTI
Sbjct: 1 MQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTI 60
Query: 198 FDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNN 257
FDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNN
Sbjct: 61 FDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNN 120
Query: 258 MGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHER 317
MGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHER
Sbjct: 121 MGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHER 180
Query: 318 LVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNM 377
LVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNM
Sbjct: 181 LVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNM 240
Query: 378 LGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRT 437
LGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRT
Sbjct: 241 LGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRT 300
Query: 438 RMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKIT 497
RMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKIT
Sbjct: 301 RMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKIT 360
Query: 498 LGVQSR 503
LGVQSR
Sbjct: 361 LGVQSR 366
>gi|48476342 solute carrier family 25, member 23 [Homo sapiens]
Length = 468
Score = 631 bits (1627), Expect = 0.0
Identities = 315/463 (68%), Positives = 369/463 (79%), Gaps = 1/463 (0%)
Query: 42 GGPDHRLRLWRLFQTLDVNRDGGLCVNDLAVGLRRLGLHRTE-GELQKIVQAGDKDLDGQ 100
G + R R RLF+ LD N+DG + V++L GL RLG + G Q I GD D DG
Sbjct: 6 GDAERRQRWGRLFEELDSNKDGRVDVHELRQGLARLGGGNPDPGAQQGISSEGDADPDGG 65
Query: 101 LDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSM 160
LD EEF YLQ+ E++L L+F SLD+ DG ID EI QS R LG+ IS +QAEKIL SM
Sbjct: 66 LDLEEFSRYLQEREQRLLLMFHSLDRNQDGHIDVSEIQQSFRALGISISLEQAEKILHSM 125
Query: 161 DKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMW 220
D++GTMTIDW EWRD+ LLH +EN+ +++ +WKHST+ D+GE LTVPDEF+ +E+ TGMW
Sbjct: 126 DRDGTMTIDWQEWRDHFLLHSLENVEDVLYFWKHSTVLDIGECLTVPDEFSKQEKLTGMW 185
Query: 221 WRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGN 280
W+ LVAG AGAVSRT TAPLDRLKV MQVHAS++N + I+GG M+ EGG RSLWRGN
Sbjct: 186 WKQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLNILGGLRSMVLEGGIRSLWRGN 245
Query: 281 GINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKT 340
GINVLKIAPESAIKFMAYEQIKR + QETL + ER VAGSLAGA AQ+ IYPMEVLKT
Sbjct: 246 GINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQERFVAGSLAGATAQTIIYPMEVLKT 305
Query: 341 RMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQ 400
R+ LR+TGQY G+LDCARRIL REG AFY+GY+PN+LGIIPYAGIDLAVYETLKN WLQ
Sbjct: 306 RLTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETLKNWWLQ 365
Query: 401 HYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHI 460
Y+ +SADPG+ VLLACGT+SSTCGQ+ASYPLALVRTRMQAQASIEG P+++M L +HI
Sbjct: 366 QYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASIEGGPQLSMLGLLRHI 425
Query: 461 LRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 503
L EG GLYRG+APNFMKVIPAVSISYVVYEN+K LGV SR
Sbjct: 426 LSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQALGVTSR 468
>gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo
sapiens]
Length = 477
Score = 609 bits (1570), Expect = e-174
Identities = 293/465 (63%), Positives = 369/465 (79%)
Query: 39 AICGGPDHRLRLWRLFQTLDVNRDGGLCVNDLAVGLRRLGLHRTEGELQKIVQAGDKDLD 98
A C + R LFQ LD N DG + + +L GLR LG+ + +KI GD + D
Sbjct: 13 AACQDAEQPTRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEEKIFTTGDVNKD 72
Query: 99 GQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILK 158
G+LDFEEF+ YL+DHEKK++L FKSLDK NDG+I+A EI+QSL+ LG+ ISEQQAE IL+
Sbjct: 73 GKLDFEEFMKYLKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAELILQ 132
Query: 159 SMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTG 218
S+D +GTMT+DWNEWRDY L +PV +I EII +WKHST D+G++LT+PDEFT +E+++G
Sbjct: 133 SIDVDGTMTVDWNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTIPDEFTEDEKKSG 192
Query: 219 MWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWR 278
WWR L+AGG AGAVSRT TAPLDRLK++MQVH S+S+ M I GGF QM++EGG RSLWR
Sbjct: 193 QWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWR 252
Query: 279 GNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVL 338
GNG NV+KIAPE+A+KF AYEQ K+L+ + + + ER ++GS+AGA AQ+ IYPMEV+
Sbjct: 253 GNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVM 312
Query: 339 KTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAW 398
KTR+A+ KTGQYSG+ DCA++IL EG+ AFYKGYVPN+LGIIPYAGIDLAVYE LK+ W
Sbjct: 313 KTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYW 372
Query: 399 LQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFK 458
L ++A +S +PGV VLL CG +SSTCGQLASYPLALVRTRMQAQA +EG+P++ M LF+
Sbjct: 373 LDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFR 432
Query: 459 HILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 503
I+ EG GLYRG+ PNFMKV+PAV ISYVVYEN+K TLGV +
Sbjct: 433 RIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQTLGVTQK 477
>gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo
sapiens]
Length = 458
Score = 603 bits (1554), Expect = e-172
Identities = 289/451 (64%), Positives = 365/451 (80%)
Query: 53 LFQTLDVNRDGGLCVNDLAVGLRRLGLHRTEGELQKIVQAGDKDLDGQLDFEEFVHYLQD 112
LF LD N+DG L + +L GL +G ++ E +KI GD + DG+LDFEEF+ YL+D
Sbjct: 8 LFWYLDYNKDGTLDIFELQEGLEDVGAIQSLEEAKKIFTTGDVNKDGKLDFEEFMKYLKD 67
Query: 113 HEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNE 172
HEKK++L FKSLDK NDG+I+A EI+QSL+ LG+ ISEQQAE IL+S+D +GTMT+DWNE
Sbjct: 68 HEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAELILQSIDVDGTMTVDWNE 127
Query: 173 WRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGA 232
WRDY L +PV +I EII +WKHST D+G++LT+PDEFT +E+++G WWR L+AGG AGA
Sbjct: 128 WRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTIPDEFTEDEKKSGQWWRQLLAGGIAGA 187
Query: 233 VSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESA 292
VSRT TAPLDRLK++MQVH S+S+ M I GGF QM++EGG RSLWRGNG NV+KIAPE+A
Sbjct: 188 VSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTNVIKIAPETA 247
Query: 293 IKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSG 352
+KF AYEQ K+L+ + + + ER ++GS+AGA AQ+ IYPMEV+KTR+A+ KTGQYSG
Sbjct: 248 VKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTRLAVGKTGQYSG 307
Query: 353 MLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVF 412
+ DCA++IL EG+ AFYKGYVPN+LGIIPYAGIDLAVYE LK+ WL ++A +S +PGV
Sbjct: 308 IYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVM 367
Query: 413 VLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRG 472
VLL CG +SSTCGQLASYPLALVRTRMQAQA +EG+P++ M LF+ I+ EG GLYRG
Sbjct: 368 VLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRG 427
Query: 473 LAPNFMKVIPAVSISYVVYENLKITLGVQSR 503
+ PNFMKV+PAV ISYVVYEN+K TLGV +
Sbjct: 428 ITPNFMKVLPAVGISYVVYENMKQTLGVTQK 458
Score = 92.8 bits (229), Expect = 6e-19
Identities = 86/388 (22%), Positives = 165/388 (42%), Gaps = 41/388 (10%)
Query: 45 DHRLRLWRLFQTLDVNRDGGLCVNDLAVGLRRLGLHRTEGELQKIVQAGDKDLDGQLDFE 104
DH ++ F++LD N DG + +++ L+ LGL +E + + I+Q+ D D +D+
Sbjct: 67 DHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAELILQSIDVDGTMTVDWN 126
Query: 105 EFVHY-----LQDHEKKLRLVFKSL----------------DKKNDGRIDAQEIMQSLRD 143
E+ Y + D E+ +R S D+K G+ Q + +
Sbjct: 127 EWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTIPDEFTEDEKKSGQWWRQLLAGGIAG 186
Query: 144 LGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWK--HSTIFDVG 201
+ S +++ M +G+ + N + + + I + W+ + + +
Sbjct: 187 AVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSL---WRGNGTNVIKIA 243
Query: 202 ENLTVP-------DEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASR 254
V + EE Q + ++G AGA ++T P++ +K + V
Sbjct: 244 PETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTRLAV-GKT 302
Query: 255 SNNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRL----VGSDQE 310
GI ++++ G + ++G N+L I P + I YE +K D
Sbjct: 303 GQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSV 362
Query: 311 TLRIHERLVAGSLAGAIAQSSIYPMEVLKTRM---ALRKTGQYSGMLDCARRILAREGVA 367
+ L G+L+ Q + YP+ +++TRM A+ + M+ RRI+++EG+
Sbjct: 363 NPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIP 422
Query: 368 AFYKGYVPNMLGIIPYAGIDLAVYETLK 395
Y+G PN + ++P GI VYE +K
Sbjct: 423 GLYRGITPNFMKVLPAVGISYVVYENMK 450
>gi|149274607 solute carrier family 25, member 41 [Homo sapiens]
Length = 370
Score = 324 bits (830), Expect = 1e-88
Identities = 172/304 (56%), Positives = 217/304 (71%), Gaps = 3/304 (0%)
Query: 197 IFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSN 256
+ D GE L VP E + + +W + L++G AGAVSRT TAPLDR KV MQV++S++N
Sbjct: 70 VLDTGEQLMVPVEVLEVDNKEALW-KFLLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTN 128
Query: 257 NMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHE 316
++GG M++EGG RSLWRGNGINVLKIAPE AIKF +EQ K Q + E
Sbjct: 129 FTNLLGGLQSMVQEGGFRSLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCGIQGSPPFQE 188
Query: 317 RLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPN 376
RL+AGSLA AI+Q+ I PMEVLKTR+ LR+TGQY G+LDCAR+IL REG A Y+GY+PN
Sbjct: 189 RLLAGSLAVAISQTLINPMEVLKTRLTLRRTGQYKGLLDCARQILQREGTRALYRGYLPN 248
Query: 377 MLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVR 436
MLGIIPYA DLAVYE L+ W++ + DP V L+ T+S+TCGQ+ASYPL LVR
Sbjct: 249 MLGIIPYACTDLAVYEMLQCFWVKS-GRDMGDPSGLVSLSSVTLSTTCGQMASYPLTLVR 307
Query: 437 TRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKI 496
TRMQAQ ++EG+ TM + + IL +G GLYRG+ P +KV+PA ISYVVYE +K
Sbjct: 308 TRMQAQDTVEGS-NPTMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKK 366
Query: 497 TLGV 500
TLG+
Sbjct: 367 TLGI 370
>gi|60460887 solute carrier family 25, member 42 [Homo sapiens]
Length = 318
Score = 176 bits (446), Expect = 4e-44
Identities = 106/280 (37%), Positives = 157/280 (56%), Gaps = 8/280 (2%)
Query: 224 LVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGIN 283
L+ G AGA+++T APLDR K++ QV + R + G SLWRGN
Sbjct: 37 LLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYLNEGFLSLWRGNSAT 96
Query: 284 VLKIAPESAIKFMAYEQIKRLVGSDQ----ETLRIHERLVAGSLAGAIAQSSIYPMEVLK 339
++++ P +AI+F A+E+ KR++GS E L RL AG+LAG A S YP+++++
Sbjct: 97 MVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALAGTTAASLTYPLDLVR 156
Query: 340 TRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWL 399
RMA+ YS + RI EG+ Y G++P +LG+IPYAG+ YETLK+ L
Sbjct: 157 ARMAVTPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTYETLKS--L 214
Query: 400 QHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKH 459
P F + G + GQ ASYPL +VR RMQ A + G P +++ +
Sbjct: 215 HREYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVRRRMQT-AGVTGYPRASIARTLRT 273
Query: 460 ILRTEGAF-GLYRGLAPNFMKVIPAVSISYVVYENLKITL 498
I+R EGA GLY+GL+ N++K AV IS+ ++ ++I L
Sbjct: 274 IVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFDLMQIML 313
Score = 77.8 bits (190), Expect = 2e-14
Identities = 53/197 (26%), Positives = 93/197 (47%), Gaps = 14/197 (7%)
Query: 305 VGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRI---L 361
V S ++ ++ L+ G+LAGA+A++++ P++ +T++ + + + + R +
Sbjct: 24 VSSKRDHRQVLSSLLPGALAGALAKTAVAPLD--RTKIIFQVSSKRFSAKEAFRVLYYTY 81
Query: 362 AREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMS 421
EG + ++G M+ ++PYA I + +E K +Y + L G ++
Sbjct: 82 LNEGFLSLWRGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALA 141
Query: 422 STCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFK---HILRTEGAFGLYRGLAPNFM 478
T +YPL LVR RM P+ S++F I R EG LY G P +
Sbjct: 142 GTTAASLTYPLDLVRARMAV------TPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVL 195
Query: 479 KVIPAVSISYVVYENLK 495
VIP +S+ YE LK
Sbjct: 196 GVIPYAGLSFFTYETLK 212
Score = 30.4 bits (67), Expect = 3.9
Identities = 19/82 (23%), Positives = 35/82 (42%), Gaps = 2/82 (2%)
Query: 418 GTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNF 477
G ++ + A PL + Q + A E + ++ EG L+RG +
Sbjct: 40 GALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYL--NEGFLSLWRGNSATM 97
Query: 478 MKVIPAVSISYVVYENLKITLG 499
++V+P +I + +E K LG
Sbjct: 98 VRVVPYAAIQFSAHEEYKRILG 119
>gi|27544933 solute carrier family 25, member 16 [Homo sapiens]
Length = 332
Score = 171 bits (434), Expect = 1e-42
Identities = 102/296 (34%), Positives = 164/296 (55%), Gaps = 15/296 (5%)
Query: 215 RQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGAR 274
R+ W R +AGG AG ++T APLDR+KVL+Q H ++G+ + ++ G
Sbjct: 31 RRDFYWLRSFLAGGIAGCCAKTTVAPLDRVKVLLQAHNHHYKHLGVFSALRAVPQKEGFL 90
Query: 275 SLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYP 334
L++GNG +++I P AI+FMA+E K L+ + RL+AGS+AG A YP
Sbjct: 91 GLYKGNGAMMIRIFPYGAIQFMAFEHYKTLITTKLGISGHVHRLMAGSMAGMTAVICTYP 150
Query: 335 MEVLKTRMALRKTGQ--YSGMLDCARRILARE-GVAAFYKGYVPNMLGIIPYAGIDLAVY 391
+++++ R+A + G+ Y+G++ + I A+E G FY+G +P +LG+ PYAG+ +
Sbjct: 151 LDMVRVRLAFQVKGEHSYTGIIHAFKTIYAKEGGFFGFYRGLMPTILGMAPYAGVSFFTF 210
Query: 392 ETLKNAWLQHYAV-----NSADPGVFVL-----LACGTMSSTCGQLASYPLALVRTRMQA 441
TLK+ L H +S +P V VL L CG ++ Q SYP + R RMQ
Sbjct: 211 GTLKSVGLSHAPTLLGRPSSDNPNVLVLKTHVNLLCGGVAGAIAQTISYPFDVTRRRMQL 270
Query: 442 QASI-EGAPEVTMSSLFKHILRTEG-AFGLYRGLAPNFMKVIPAVSISYVVYENLK 495
+ E +TM K++ G GLYRGL+ N+++ IP+ ++++ YE +K
Sbjct: 271 GTVLPEFEKCLTMRDTMKYVYGHHGIRKGLYRGLSLNYIRCIPSQAVAFTTYELMK 326
Score = 37.7 bits (86), Expect = 0.025
Identities = 25/90 (27%), Positives = 43/90 (47%), Gaps = 14/90 (15%)
Query: 223 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHA---------SRSNNMGIVGGFTQMIREGGA 273
+L+ GG AGA+++T + P D + MQ+ + + M V G G
Sbjct: 243 NLLCGGVAGAIAQTISYPFDVTRRRMQLGTVLPEFEKCLTMRDTMKYVYG-----HHGIR 297
Query: 274 RSLWRGNGINVLKIAPESAIKFMAYEQIKR 303
+ L+RG +N ++ P A+ F YE +K+
Sbjct: 298 KGLYRGLSLNYIRCIPSQAVAFTTYELMKQ 327
>gi|21687151 mitochondrial solute carrier protein [Homo sapiens]
Length = 341
Score = 125 bits (313), Expect = 1e-28
Identities = 84/285 (29%), Positives = 139/285 (48%), Gaps = 18/285 (6%)
Query: 222 RHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNG 281
+ L+ G AG +S + TAPL+ VL QV R + G ++ R G R+LW+GN
Sbjct: 14 QRLLCAGLAGTLSLSLTAPLELATVLAQVGVVRGHARGPWATGHRVWRAEGLRALWKGNA 73
Query: 282 INVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTR 341
+ L++ P SA++ AY + L D + ++AGSLAG ++ YP +++KTR
Sbjct: 74 VACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSLAGMVSTIVTYPTDLIKTR 133
Query: 342 MALRK--TGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWL 399
+ ++ Y G+L I +EG A Y+G ++G +P++ L VY L+ W
Sbjct: 134 LIMQNILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAGSLLVYMNLEKIW- 192
Query: 400 QHYAVNSADPGVFVL---LACGTMSSTCGQLASYPLALVRTRMQAQASI---EGAPEVTM 453
+ F L A +++ Q S+P V+ +MQAQ+ G +V
Sbjct: 193 ------NGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHF 246
Query: 454 S---SLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 495
S F+ I++ +G GL+ GL N +K++P I + +E K
Sbjct: 247 SGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCK 291
Score = 84.3 bits (207), Expect = 2e-16
Identities = 52/189 (27%), Positives = 93/189 (49%), Gaps = 10/189 (5%)
Query: 221 WRHLVAGGGAGAVSRTCTAPLDRLKV-LMQVHASRSNNMGIVGGFTQMIREGGARSLWRG 279
W ++AG AG VS T P D +K L+ + + G++ F+ + ++ G +L+RG
Sbjct: 107 WSSIMAGSLAGMVSTIVTYPTDLIKTRLIMQNILEPSYRGLLHAFSTIYQQEGFLALYRG 166
Query: 280 NGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLK 339
+ V+ P SA + Y ++++ ++ + + LA A+ Q+ +P E +K
Sbjct: 167 VSLTVVGALPFSAGSLLVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVK 226
Query: 340 TRMA-----LRKTG----QYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAV 390
+M L +G +SG +DC R+I+ +GV + G N+L I+PY GI +
Sbjct: 227 RKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFST 286
Query: 391 YETLKNAWL 399
+E K L
Sbjct: 287 FEFCKRICL 295
>gi|13775208 solute carrier family 25 (mitochondrial carrier;
adenine nucleotide translocator), member 31 [Homo
sapiens]
Length = 315
Score = 116 bits (290), Expect = 5e-26
Identities = 83/290 (28%), Positives = 137/290 (47%), Gaps = 22/290 (7%)
Query: 222 RHLVAGGGAGAVSRTCTAPLDRLKVLMQVHAS------RSNNMGIVGGFTQMIREGGARS 275
+ L+AGG A AVS+T AP++R+K+L+QV AS + G+V ++ RE G S
Sbjct: 22 KDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFS 81
Query: 276 LWRGNGINVLKIAPESAIKFMAYEQIKRL----VGSDQETLR-IHERLVAGSLAGAIAQS 330
WRGN NV++ P A+ F ++ K+L V +++ R L +G AGA +
Sbjct: 82 FWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLC 141
Query: 331 SIYPMEVLKTRMAL-----RKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 385
+YP++ +TR+ + + Q+ G+ DC +I +G+A Y+G+ ++ GII Y
Sbjct: 142 VVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYRA 201
Query: 386 IDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASI 445
Y+T+K V + +TC + SYP VR RM Q+
Sbjct: 202 SYFGAYDTVKG-----LLPKPKKTPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQSGE 256
Query: 446 EGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 495
F I + EG +RG N ++ ++ V+Y+ +K
Sbjct: 257 AKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLRGTGG-ALVLVLYDKIK 305
Score = 62.0 bits (149), Expect = 1e-09
Identities = 49/177 (27%), Positives = 84/177 (47%), Gaps = 15/177 (8%)
Query: 213 EERQTGMWWRHLVA-GGGAGAVSRTCTAPLDRLKVLMQVHASRSNN----MGIVGGFTQM 267
+E+Q W+ +A GG AGA S PLD + + V + G+ ++
Sbjct: 117 KEKQFWRWFLANLASGGAAGATSLCVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKI 176
Query: 268 IREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAI 327
+ G L++G G++V I A F AY+ +K L+ ++T LV+ +A +
Sbjct: 177 AKSDGIAGLYQGFGVSVQGIIVYRASYFGAYDTVKGLLPKPKKT----PFLVSFFIAQVV 232
Query: 328 AQSS---IYPMEVLKTRMALRK---TGQYSGMLDCARRILAREGVAAFYKGYVPNML 378
S YP + ++ RM ++ QY G LDC +I EG+++F++G N+L
Sbjct: 233 TTCSGILSYPFDTVRRRMMMQSGEAKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVL 289
>gi|156071459 solute carrier family 25, member 5 [Homo sapiens]
Length = 298
Score = 115 bits (289), Expect = 7e-26
Identities = 88/296 (29%), Positives = 148/296 (50%), Gaps = 32/296 (10%)
Query: 222 RHLVAGGGAGAVSRTCTAPLDRLKVLMQV-HASR-----SNNMGIVGGFTQMIREGGARS 275
+ +AGG A A+S+T AP++R+K+L+QV HAS+ GI+ ++ +E G S
Sbjct: 10 KDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLS 69
Query: 276 LWRGNGINVLKIAPESAIKFMAYEQIKR--LVGSDQET---LRIHERLVAGSLAGAIAQS 330
WRGN NV++ P A+ F ++ K+ L G D+ T L L +G AGA +
Sbjct: 70 FWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSLC 129
Query: 331 SIYPMEVLKTRMA--LRKTG---QYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 385
+YP++ +TR+A + K G ++ G+ DC +I +G+ Y+G+ ++ GII Y
Sbjct: 130 FVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRA 189
Query: 386 IDLAVYETLKNAWLQHYAVNSADPG----VFVLLACGTMSSTCGQLASYPLALVRTRMQA 441
+Y+T K DP V + T+++ G L SYP VR RM
Sbjct: 190 AYFGIYDTAKGM--------LPDPKNTHIVISWMIAQTVTAVAG-LTSYPFDTVRRRMMM 240
Query: 442 QASIEGAPEVTMSSL--FKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 495
Q+ +G + +L ++ I R EG ++G N ++ + + V+Y+ +K
Sbjct: 241 QSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGGAFV-LVLYDEIK 295
>gi|156071462 solute carrier family 25, member A6 [Homo sapiens]
Length = 298
Score = 115 bits (287), Expect = 1e-25
Identities = 89/296 (30%), Positives = 149/296 (50%), Gaps = 32/296 (10%)
Query: 222 RHLVAGGGAGAVSRTCTAPLDRLKVLMQV-HASRS-----NNMGIVGGFTQMIREGGARS 275
+ +AGG A A+S+T AP++R+K+L+QV HAS+ GIV ++ +E G S
Sbjct: 10 KDFLAGGIAAAISKTAVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVRIPKEQGVLS 69
Query: 276 LWRGNGINVLKIAPESAIKFMAYEQIKR--LVGSDQET---LRIHERLVAGSLAGAIAQS 330
WRGN NV++ P A+ F ++ K+ L G D+ T L +G AGA +
Sbjct: 70 FWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKHTQFWRYFAGNLASGGAAGATSLC 129
Query: 331 SIYPMEVLKTRMA--LRKTG---QYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 385
+YP++ +TR+A + K+G ++ G+ DC +I +G+ Y+G+ ++ GII Y
Sbjct: 130 FVYPLDFARTRLAADVGKSGTEREFRGLGDCLVKITKSDGIRGLYQGFSVSVQGIIIYRA 189
Query: 386 IDLAVYETLKNAWLQHYAVNSADPG----VFVLLACGTMSSTCGQLASYPLALVRTRMQA 441
VY+T K DP V + T+++ G + SYP VR RM
Sbjct: 190 AYFGVYDTAKGM--------LPDPKNTHIVVSWMIAQTVTAVAG-VVSYPFDTVRRRMMM 240
Query: 442 QASIEGAPEVTMSSL--FKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 495
Q+ +GA + ++ ++ I R EG ++G N ++ + + V+Y+ LK
Sbjct: 241 QSGRKGADIMYTGTVDCWRKIFRDEGGKAFFKGAWSNVLRGMGGAFV-LVLYDELK 295
Score = 63.9 bits (154), Expect = 3e-10
Identities = 46/197 (23%), Positives = 90/197 (45%), Gaps = 10/197 (5%)
Query: 309 QETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTG-------QYSGMLDCARRIL 361
++ + + +AG +A AI+++++ P+E +K + ++ QY G++DC RI
Sbjct: 3 EQAISFAKDFLAGGIAAAISKTAVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVRIP 62
Query: 362 AREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFV-LLACGTM 420
+GV +F++G + N++ P ++ A + K +L ++ F LA G
Sbjct: 63 KEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKHTQFWRYFAGNLASGGA 122
Query: 421 SSTCGQLASYPLALVRTRMQAQASIEGAPEV--TMSSLFKHILRTEGAFGLYRGLAPNFM 478
+ YPL RTR+ A G + I +++G GLY+G + +
Sbjct: 123 AGATSLCFVYPLDFARTRLAADVGKSGTEREFRGLGDCLVKITKSDGIRGLYQGFSVSVQ 182
Query: 479 KVIPAVSISYVVYENLK 495
+I + + VY+ K
Sbjct: 183 GIIIYRAAYFGVYDTAK 199
>gi|186928856 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 115 bits (287), Expect = 1e-25
Identities = 75/285 (26%), Positives = 134/285 (47%), Gaps = 17/285 (5%)
Query: 225 VAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNM-------GIVGGFTQMIREGGARSLW 277
VAG +G V+R +P D +K+ Q+ R + GI+ Q+++E G + W
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 278 RGNGINVLKIAPESAIKFMAYEQIKRLV--GSDQETLRIHERLVAGSLAGAIAQSSIYPM 335
+G+ + A++F+++E + LV GS + V G LA +A +++P+
Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPV 139
Query: 336 EVLKTRMALRKTGQ-YSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETL 394
+VL+TR A + + Y+ + + EG FYKG P ++ I PYAG+ + Y +L
Sbjct: 140 DVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSL 199
Query: 395 KNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQ------AQASIEGA 448
K+ + L CG+ + + +YPL L + R+Q A+A+
Sbjct: 200 KHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQV 259
Query: 449 PEVT-MSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYE 492
+ K +L+ EGA G ++GL+P+ +K + + YE
Sbjct: 260 RRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
Score = 85.9 bits (211), Expect = 8e-17
Identities = 57/187 (30%), Positives = 92/187 (49%), Gaps = 16/187 (8%)
Query: 319 VAGSLAGAIAQSSIYPMEVLKTRMALRK--------TGQYSGMLDCARRILAREGVAAFY 370
VAGS++G + ++ I P +V+K R L+ + +Y G+L +R+IL EG AF+
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 371 KGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASY 430
KG+VP + I Y + +E L L H V CG +++ L +
Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTE--LVHRGSVYDAREFSVHFVCGGLAACMATLTVH 137
Query: 431 PLALVRTRMQAQASIEGAPEV--TMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISY 488
P+ ++RTR AQ G P+V T+ + R+EG Y+GLAP + + P + +
Sbjct: 138 PVDVLRTRFAAQ----GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQF 193
Query: 489 VVYENLK 495
Y +LK
Sbjct: 194 SCYSSLK 200
Score = 73.6 bits (179), Expect = 4e-13
Identities = 49/193 (25%), Positives = 84/193 (43%), Gaps = 20/193 (10%)
Query: 223 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGI 282
H V GG A ++ P+D L+ + M R G + ++G
Sbjct: 121 HFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAP 180
Query: 283 NVLKIAPESAIKFMAYEQIKRLV-------GSDQETLRIHERLVAGSLAGAIAQSSIYPM 335
++ I P + ++F Y +K L G E L + L+ GS AG I+++ YP+
Sbjct: 181 TLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENL---QNLLCGSGAGVISKTLTYPL 237
Query: 336 EVLKTRM----------ALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 385
++ K R+ A + +Y G++DCA+++L +EG F+KG P++L G
Sbjct: 238 DLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTG 297
Query: 386 IDLAVYETLKNAW 398
YE N +
Sbjct: 298 FMFFSYEFFCNVF 310
Score = 43.1 bits (100), Expect = 6e-04
Identities = 27/87 (31%), Positives = 46/87 (52%), Gaps = 9/87 (10%)
Query: 222 RHLVAGGGAGAVSRTCTAPLDRLKVLMQV----HASRS-----NNMGIVGGFTQMIREGG 272
++L+ G GAG +S+T T PLD K +QV HA + G++ Q++++ G
Sbjct: 218 QNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEG 277
Query: 273 ARSLWRGNGINVLKIAPESAIKFMAYE 299
A ++G ++LK A + F +YE
Sbjct: 278 ALGFFKGLSPSLLKAALSTGFMFFSYE 304
>gi|186928860 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 115 bits (287), Expect = 1e-25
Identities = 75/285 (26%), Positives = 134/285 (47%), Gaps = 17/285 (5%)
Query: 225 VAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNM-------GIVGGFTQMIREGGARSLW 277
VAG +G V+R +P D +K+ Q+ R + GI+ Q+++E G + W
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 278 RGNGINVLKIAPESAIKFMAYEQIKRLV--GSDQETLRIHERLVAGSLAGAIAQSSIYPM 335
+G+ + A++F+++E + LV GS + V G LA +A +++P+
Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPV 139
Query: 336 EVLKTRMALRKTGQ-YSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETL 394
+VL+TR A + + Y+ + + EG FYKG P ++ I PYAG+ + Y +L
Sbjct: 140 DVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSL 199
Query: 395 KNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQ------AQASIEGA 448
K+ + L CG+ + + +YPL L + R+Q A+A+
Sbjct: 200 KHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQV 259
Query: 449 PEVT-MSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYE 492
+ K +L+ EGA G ++GL+P+ +K + + YE
Sbjct: 260 RRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
Score = 85.9 bits (211), Expect = 8e-17
Identities = 57/187 (30%), Positives = 92/187 (49%), Gaps = 16/187 (8%)
Query: 319 VAGSLAGAIAQSSIYPMEVLKTRMALRK--------TGQYSGMLDCARRILAREGVAAFY 370
VAGS++G + ++ I P +V+K R L+ + +Y G+L +R+IL EG AF+
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 371 KGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASY 430
KG+VP + I Y + +E L L H V CG +++ L +
Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTE--LVHRGSVYDAREFSVHFVCGGLAACMATLTVH 137
Query: 431 PLALVRTRMQAQASIEGAPEV--TMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISY 488
P+ ++RTR AQ G P+V T+ + R+EG Y+GLAP + + P + +
Sbjct: 138 PVDVLRTRFAAQ----GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQF 193
Query: 489 VVYENLK 495
Y +LK
Sbjct: 194 SCYSSLK 200
Score = 73.6 bits (179), Expect = 4e-13
Identities = 49/193 (25%), Positives = 84/193 (43%), Gaps = 20/193 (10%)
Query: 223 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGI 282
H V GG A ++ P+D L+ + M R G + ++G
Sbjct: 121 HFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAP 180
Query: 283 NVLKIAPESAIKFMAYEQIKRLV-------GSDQETLRIHERLVAGSLAGAIAQSSIYPM 335
++ I P + ++F Y +K L G E L + L+ GS AG I+++ YP+
Sbjct: 181 TLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENL---QNLLCGSGAGVISKTLTYPL 237
Query: 336 EVLKTRM----------ALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 385
++ K R+ A + +Y G++DCA+++L +EG F+KG P++L G
Sbjct: 238 DLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTG 297
Query: 386 IDLAVYETLKNAW 398
YE N +
Sbjct: 298 FMFFSYEFFCNVF 310
Score = 43.1 bits (100), Expect = 6e-04
Identities = 27/87 (31%), Positives = 46/87 (52%), Gaps = 9/87 (10%)
Query: 222 RHLVAGGGAGAVSRTCTAPLDRLKVLMQV----HASRS-----NNMGIVGGFTQMIREGG 272
++L+ G GAG +S+T T PLD K +QV HA + G++ Q++++ G
Sbjct: 218 QNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEG 277
Query: 273 ARSLWRGNGINVLKIAPESAIKFMAYE 299
A ++G ++LK A + F +YE
Sbjct: 278 ALGFFKGLSPSLLKAALSTGFMFFSYE 304
>gi|186928858 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 115 bits (287), Expect = 1e-25
Identities = 75/285 (26%), Positives = 134/285 (47%), Gaps = 17/285 (5%)
Query: 225 VAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNM-------GIVGGFTQMIREGGARSLW 277
VAG +G V+R +P D +K+ Q+ R + GI+ Q+++E G + W
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 278 RGNGINVLKIAPESAIKFMAYEQIKRLV--GSDQETLRIHERLVAGSLAGAIAQSSIYPM 335
+G+ + A++F+++E + LV GS + V G LA +A +++P+
Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPV 139
Query: 336 EVLKTRMALRKTGQ-YSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETL 394
+VL+TR A + + Y+ + + EG FYKG P ++ I PYAG+ + Y +L
Sbjct: 140 DVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSL 199
Query: 395 KNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQ------AQASIEGA 448
K+ + L CG+ + + +YPL L + R+Q A+A+
Sbjct: 200 KHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQV 259
Query: 449 PEVT-MSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYE 492
+ K +L+ EGA G ++GL+P+ +K + + YE
Sbjct: 260 RRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
Score = 85.9 bits (211), Expect = 8e-17
Identities = 57/187 (30%), Positives = 92/187 (49%), Gaps = 16/187 (8%)
Query: 319 VAGSLAGAIAQSSIYPMEVLKTRMALRK--------TGQYSGMLDCARRILAREGVAAFY 370
VAGS++G + ++ I P +V+K R L+ + +Y G+L +R+IL EG AF+
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 371 KGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASY 430
KG+VP + I Y + +E L L H V CG +++ L +
Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTE--LVHRGSVYDAREFSVHFVCGGLAACMATLTVH 137
Query: 431 PLALVRTRMQAQASIEGAPEV--TMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISY 488
P+ ++RTR AQ G P+V T+ + R+EG Y+GLAP + + P + +
Sbjct: 138 PVDVLRTRFAAQ----GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQF 193
Query: 489 VVYENLK 495
Y +LK
Sbjct: 194 SCYSSLK 200
Score = 73.6 bits (179), Expect = 4e-13
Identities = 49/193 (25%), Positives = 84/193 (43%), Gaps = 20/193 (10%)
Query: 223 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGI 282
H V GG A ++ P+D L+ + M R G + ++G
Sbjct: 121 HFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAP 180
Query: 283 NVLKIAPESAIKFMAYEQIKRLV-------GSDQETLRIHERLVAGSLAGAIAQSSIYPM 335
++ I P + ++F Y +K L G E L + L+ GS AG I+++ YP+
Sbjct: 181 TLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENL---QNLLCGSGAGVISKTLTYPL 237
Query: 336 EVLKTRM----------ALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 385
++ K R+ A + +Y G++DCA+++L +EG F+KG P++L G
Sbjct: 238 DLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTG 297
Query: 386 IDLAVYETLKNAW 398
YE N +
Sbjct: 298 FMFFSYEFFCNVF 310
Score = 43.1 bits (100), Expect = 6e-04
Identities = 27/87 (31%), Positives = 46/87 (52%), Gaps = 9/87 (10%)
Query: 222 RHLVAGGGAGAVSRTCTAPLDRLKVLMQV----HASRS-----NNMGIVGGFTQMIREGG 272
++L+ G GAG +S+T T PLD K +QV HA + G++ Q++++ G
Sbjct: 218 QNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEG 277
Query: 273 ARSLWRGNGINVLKIAPESAIKFMAYE 299
A ++G ++LK A + F +YE
Sbjct: 278 ALGFFKGLSPSLLKAALSTGFMFFSYE 304
>gi|21314739 solute carrier family 25, member 32 [Homo sapiens]
Length = 315
Score = 113 bits (283), Expect = 4e-25
Identities = 86/286 (30%), Positives = 128/286 (44%), Gaps = 17/286 (5%)
Query: 221 WRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHAS---RSNNMGIVGGFTQMIREGGARSLW 277
+ +L+AG G +S PLD +K+ V R GI+ T + + G R L+
Sbjct: 23 YENLIAGVSGGVLSNLALHPLDLVKIRFAVSDGLELRPKYNGILHCLTTIWKLDGLRGLY 82
Query: 278 RGNGINVLKIAPESAIKFMAYEQIKRLVGSDQ-ETLRIHERLVAGSLAGAIAQSSIYPME 336
+G N+ + F Y IK + E L E LV+ + AGA+ P+
Sbjct: 83 QGVTPNIWGAGLSWGLYFFFYNAIKSYKTEGRAERLEATEYLVSAAEAGAMTLCITNPLW 142
Query: 337 VLKTRMALRKTG-------QYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLA 389
V KTR+ L+ QY GM D +I EGV YKG+VP + G + +
Sbjct: 143 VTKTRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEGVRGLYKGFVPGLFGT-SHGALQFM 201
Query: 390 VYETLKNAWLQHY-AVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGA 448
YE LK + QH + A ++ +S A+YP +VR R+Q Q
Sbjct: 202 AYELLKLKYNQHINRLPEAQLSTVEYISVAALSKIFAVAATYPYQVVRARLQDQHMFYSG 261
Query: 449 PEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENL 494
+ + R EG G Y+G+APN ++V PA I++VVYEN+
Sbjct: 262 ----VIDVITKTWRKEGVGGFYKGIAPNLIRVTPACCITFVVYENV 303
Score = 66.2 bits (160), Expect = 6e-11
Identities = 49/185 (26%), Positives = 90/185 (48%), Gaps = 13/185 (7%)
Query: 223 HLVAGGGAGAVSRTCTAPL--DRLKVLMQ----VHASRSNNMGIVGGFTQMIREGGARSL 276
+LV+ AGA++ T PL + ++++Q V++ G+ ++ + G R L
Sbjct: 123 YLVSAAEAGAMTLCITNPLWVTKTRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEGVRGL 182
Query: 277 WRGNGINVLKIAPESAIKFMAYEQIKRLVGSD-----QETLRIHERLVAGSLAGAIAQSS 331
++G + L A++FMAYE +K + L E + +L+ A ++
Sbjct: 183 YKGF-VPGLFGTSHGALQFMAYELLKLKYNQHINRLPEAQLSTVEYISVAALSKIFAVAA 241
Query: 332 IYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVY 391
YP +V++ R+ + YSG++D + +EGV FYKG PN++ + P I VY
Sbjct: 242 TYPYQVVRARLQDQHMF-YSGVIDVITKTWRKEGVGGFYKGIAPNLIRVTPACCITFVVY 300
Query: 392 ETLKN 396
E + +
Sbjct: 301 ENVSH 305
Score = 32.3 bits (72), Expect = 1.0
Identities = 21/82 (25%), Positives = 34/82 (41%), Gaps = 1/82 (1%)
Query: 415 LACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVT-MSSLFKHILRTEGAFGLYRGL 473
L G LA +PL LV+ R +E P+ + I + +G GLY+G+
Sbjct: 26 LIAGVSGGVLSNLALHPLDLVKIRFAVSDGLELRPKYNGILHCLTTIWKLDGLRGLYQGV 85
Query: 474 APNFMKVIPAVSISYVVYENLK 495
PN + + + Y +K
Sbjct: 86 TPNIWGAGLSWGLYFFFYNAIK 107
Score = 30.4 bits (67), Expect = 3.9
Identities = 11/47 (23%), Positives = 24/47 (51%)
Query: 259 GIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLV 305
G++ T+ R+ G ++G N++++ P I F+ YE + +
Sbjct: 261 GVIDVITKTWRKEGVGGFYKGIAPNLIRVTPACCITFVVYENVSHFL 307
>gi|55749577 solute carrier family 25 (mitochondrial carrier;
adenine nucleotide translocator), member 4 [Homo
sapiens]
Length = 298
Score = 113 bits (282), Expect = 5e-25
Identities = 84/292 (28%), Positives = 144/292 (49%), Gaps = 24/292 (8%)
Query: 222 RHLVAGGGAGAVSRTCTAPLDRLKVLMQV-HASRSNNM-----GIVGGFTQMIREGGARS 275
+ +AGG A AVS+T AP++R+K+L+QV HAS+ + GI+ ++ +E G S
Sbjct: 10 KDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLS 69
Query: 276 LWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSL-----AGAIAQS 330
WRGN NV++ P A+ F ++ K+L + + R AG+L AGA +
Sbjct: 70 FWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLC 129
Query: 331 SIYPMEVLKTRMAL-----RKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 385
+YP++ +TR+A ++ G+ DC +I +G+ Y+G+ ++ GII Y
Sbjct: 130 FVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYRA 189
Query: 386 IDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASI 445
VY+T K V+ +FV + L SYP VR RM Q+
Sbjct: 190 AYFGVYDTAKGMLPDPKNVH-----IFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGR 244
Query: 446 EGAPEVTMSSL--FKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 495
+GA + ++ ++ I + EGA ++G N ++ + + V+Y+ +K
Sbjct: 245 KGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGMGGAFV-LVLYDEIK 295
>gi|157388989 solute carrier family 25, member 36 isoform a [Homo
sapiens]
Length = 311
Score = 108 bits (271), Expect = 9e-24
Identities = 85/303 (28%), Positives = 142/303 (46%), Gaps = 41/303 (13%)
Query: 223 HLVAGGGAGAVSRTCTAPLDRLKVLMQ------------------VHASRSNNMGIVGGF 264
HL AGG G V T PL+ +K +Q +R + G +
Sbjct: 9 HLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCL 68
Query: 265 TQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGS--DQETLRIHERLVAGS 322
++ + G RSL+RG G N++ +AP AI F AY K + D ++ ++H +++ +
Sbjct: 69 KVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVH--MISAA 126
Query: 323 LAGAIAQSSIYPMEVLKTRMAL--RKTGQ-YSGMLDCARRILAREGVAAFYKGYVPNMLG 379
+AG A ++ P+ ++KTR+ L R G+ G +C R++ +G+ FY+G + G
Sbjct: 127 MAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASYAG 186
Query: 380 IIPYAGIDLAVYETLKNAWLQH----------YAVNSADPGVFVLLACGTMSSTCGQLAS 429
I I +YE++K L++ +V A V ++LA T S TC +
Sbjct: 187 ISETV-IHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAAT-SKTCATTIA 244
Query: 430 YPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYV 489
YP +VRTR++ EG + +++ EG LYRGL + ++ IP +I
Sbjct: 245 YPHEVVRTRLRE----EGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMA 300
Query: 490 VYE 492
YE
Sbjct: 301 TYE 303
Score = 46.2 bits (108), Expect = 7e-05
Identities = 30/99 (30%), Positives = 46/99 (46%), Gaps = 16/99 (16%)
Query: 413 VLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSL---------------- 456
V L G T G + + PL +V+TR+Q+ + EV ++++
Sbjct: 8 VHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHC 67
Query: 457 FKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 495
K IL EG L+RGL PN + V P+ +I + Y N K
Sbjct: 68 LKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCK 106
>gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Homo
sapiens]
Length = 325
Score = 106 bits (264), Expect = 6e-23
Identities = 89/298 (29%), Positives = 140/298 (46%), Gaps = 20/298 (6%)
Query: 211 TVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHA----SRSNNMGIVGGFTQ 266
TV +G+ W+ V GG A V+ T P+D K +QV +R + G F
Sbjct: 31 TVSHEMSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHA 90
Query: 267 MIR---EGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGS--DQETLRIHERLVAG 321
+ R E G +L+ G +L+ A IK Y+ +KRL + ETL I+ ++ G
Sbjct: 91 LFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLIN--MICG 148
Query: 322 SLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGII 381
++G I+ + P +VLK RM + + M+ I +EG ++G VP
Sbjct: 149 VVSGVISSTIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAA 208
Query: 382 PYAGIDLAVYETLKNAWLQHYAVNSADPGVFV-LLACGTMSSTCGQLASYPLALVRTRMQ 440
G++L VY+ K + + FV CG G LAS P+ +VRTRM
Sbjct: 209 IVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCG----LAGALASNPVDVVRTRMM 264
Query: 441 AQASIEGAPEV---TMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 495
Q +I G ++ T+ + K + + EG F LY+G PN++++ P I ++ YE LK
Sbjct: 265 NQRAIVGHVDLYKGTVDGILK-MWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLK 321
Score = 37.7 bits (86), Expect = 0.025
Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 4/86 (4%)
Query: 223 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNM----GIVGGFTQMIREGGARSLWR 278
H V+ G + P+D ++ M + ++ G V G +M + G +L++
Sbjct: 238 HFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYK 297
Query: 279 GNGINVLKIAPESAIKFMAYEQIKRL 304
G N L++ P + I F+ YEQ+KRL
Sbjct: 298 GFWPNWLRLGPWNIIFFITYEQLKRL 323
>gi|13259543 solute carrier family 25, member 14 isoform UCP5S [Homo
sapiens]
Length = 322
Score = 106 bits (264), Expect = 6e-23
Identities = 89/298 (29%), Positives = 140/298 (46%), Gaps = 20/298 (6%)
Query: 211 TVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHA----SRSNNMGIVGGFTQ 266
TV +G+ W+ V GG A V+ T P+D K +QV +R + G F
Sbjct: 28 TVSHEMSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHA 87
Query: 267 MIR---EGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGS--DQETLRIHERLVAG 321
+ R E G +L+ G +L+ A IK Y+ +KRL + ETL I+ ++ G
Sbjct: 88 LFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLIN--MICG 145
Query: 322 SLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGII 381
++G I+ + P +VLK RM + + M+ I +EG ++G VP
Sbjct: 146 VVSGVISSTIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAA 205
Query: 382 PYAGIDLAVYETLKNAWLQHYAVNSADPGVFV-LLACGTMSSTCGQLASYPLALVRTRMQ 440
G++L VY+ K + + FV CG G LAS P+ +VRTRM
Sbjct: 206 IVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCG----LAGALASNPVDVVRTRMM 261
Query: 441 AQASIEGAPEV---TMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 495
Q +I G ++ T+ + K + + EG F LY+G PN++++ P I ++ YE LK
Sbjct: 262 NQRAIVGHVDLYKGTVDGILK-MWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLK 318
Score = 37.7 bits (86), Expect = 0.025
Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 4/86 (4%)
Query: 223 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNM----GIVGGFTQMIREGGARSLWR 278
H V+ G + P+D ++ M + ++ G V G +M + G +L++
Sbjct: 235 HFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYK 294
Query: 279 GNGINVLKIAPESAIKFMAYEQIKRL 304
G N L++ P + I F+ YEQ+KRL
Sbjct: 295 GFWPNWLRLGPWNIIFFITYEQLKRL 320
>gi|157388991 solute carrier family 25, member 36 isoform b [Homo
sapiens]
Length = 310
Score = 105 bits (261), Expect = 1e-22
Identities = 85/303 (28%), Positives = 142/303 (46%), Gaps = 42/303 (13%)
Query: 223 HLVAGGGAGAVSRTCTAPLDRLKVLMQ------------------VHASRSNNMGIVGGF 264
HL AGG G V T PL+ +K +Q +R + G +
Sbjct: 9 HLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCL 68
Query: 265 TQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGS--DQETLRIHERLVAGS 322
++ + G RSL+RG G N++ +AP AI F AY K + D ++ ++H +++ +
Sbjct: 69 KVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVH--MISAA 126
Query: 323 LAGAIAQSSIYPMEVLKTRMAL--RKTGQ-YSGMLDCARRILAREGVAAFYKGYVPNMLG 379
+AG A ++ P+ ++KTR+ L R G+ G +C R++ +G+ FY+G + G
Sbjct: 127 MAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASYAG 186
Query: 380 IIPYAGIDLAVYETLKNAWLQH----------YAVNSADPGVFVLLACGTMSSTCGQLAS 429
I I +YE++K L++ +V A V ++LA T S TC +
Sbjct: 187 ISETV-IHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAAT-SKTCATTIA 244
Query: 430 YPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYV 489
YP +VRTR++ EG + +++ EG LYRGL + ++ IP +I
Sbjct: 245 YP-HVVRTRLRE----EGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMA 299
Query: 490 VYE 492
YE
Sbjct: 300 TYE 302
Score = 46.2 bits (108), Expect = 7e-05
Identities = 30/99 (30%), Positives = 46/99 (46%), Gaps = 16/99 (16%)
Query: 413 VLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSL---------------- 456
V L G T G + + PL +V+TR+Q+ + EV ++++
Sbjct: 8 VHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHC 67
Query: 457 FKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 495
K IL EG L+RGL PN + V P+ +I + Y N K
Sbjct: 68 LKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCK 106
>gi|14150082 mitochondrial carrier protein MGC4399 [Homo sapiens]
Length = 321
Score = 102 bits (253), Expect = 1e-21
Identities = 88/303 (29%), Positives = 133/303 (43%), Gaps = 39/303 (12%)
Query: 223 HLVAGGGAGAVSRTCTAPLDRLKVLMQ-------------VHASRSNNMGIVG------G 263
HL AGG G V T PL+ +K +Q VH + G+V G
Sbjct: 14 HLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPG 73
Query: 264 FTQMIR----EGGARSLWRGNGINVLKIAPESAIKFMAYEQIK-RLVGSDQETLRIHERL 318
Q+++ + G +SL+RG G N++ +AP A+ F Y + K + G I
Sbjct: 74 LFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPNSNIVHIF 133
Query: 319 VAGSLAGAIAQSSIYPMEVLKTRMALR---KTGQYSGMLDCARRILAREGVAAFYKGYVP 375
AGS A I S + P+ ++KTRM L + + L CAR + EG+ FY+G
Sbjct: 134 SAGS-AAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGLTA 192
Query: 376 NMLGIIPYAGIDLAVYETLKNAWLQHYAVNSAD------PGVFVLLACGTMSSTCGQLAS 429
+ GI I A+YE+LK + +SA+ F L+A +S C +
Sbjct: 193 SYAGISETI-ICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASCIA 251
Query: 430 YPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYV 489
YP ++RTR++ EG + + + R EG YRGL ++ IP +I
Sbjct: 252 YPHEVIRTRLRE----EGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLS 307
Query: 490 VYE 492
YE
Sbjct: 308 TYE 310
Score = 79.0 bits (193), Expect = 1e-14
Identities = 52/214 (24%), Positives = 96/214 (44%), Gaps = 31/214 (14%)
Query: 306 GSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMA---------------------- 343
G +E +H L AG G + P+EV+KTR+
Sbjct: 5 GQQKENTLLH--LFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGA 62
Query: 344 --LRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQH 401
+R T G+ + IL +EG + ++G PN++G+ P + A Y K +
Sbjct: 63 GMVRPTSVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGI 122
Query: 402 YAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHIL 461
+ NS + + + G+ + L + P+ +V+TRMQ + + G+ ++ +++
Sbjct: 123 FVPNS---NIVHIFSAGSAAFITNSLMN-PIWMVKTRMQLEQKVRGSKQMNTLQCARYVY 178
Query: 462 RTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 495
+TEG G YRGL ++ + + I + +YE+LK
Sbjct: 179 QTEGIRGFYRGLTASYAGISETI-ICFAIYESLK 211
Score = 62.4 bits (150), Expect = 9e-10
Identities = 48/185 (25%), Positives = 84/185 (45%), Gaps = 16/185 (8%)
Query: 223 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHAS--RSNNMGIVGGFTQMIREGGARSLWRGN 280
H+ + G A ++ + P+ +K MQ+ S M + + + G R +RG
Sbjct: 131 HIFSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGL 190
Query: 281 GINVLKIAPESAIKFMAYEQIKRLV----------GSDQETLRIHERLVAGSLAGAIAQS 330
+ I+ E+ I F YE +K+ + G+++ + + A +L+ A
Sbjct: 191 TASYAGIS-ETIICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASC 249
Query: 331 SIYPMEVLKTRMALRKTG-QYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLA 389
YP EV++TR LR+ G +Y + AR + EG AFY+G ++ IP I L+
Sbjct: 250 IAYPHEVIRTR--LREEGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLS 307
Query: 390 VYETL 394
YE +
Sbjct: 308 TYELI 312
>gi|58197562 solute carrier family 25, member 30 [Homo sapiens]
Length = 291
Score = 99.8 bits (247), Expect = 5e-21
Identities = 79/286 (27%), Positives = 126/286 (44%), Gaps = 15/286 (5%)
Query: 221 WRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNM-------GIVGGFTQMIREGGA 273
W+ V GG A + T P+D K +Q+ ++ G++ ++ RE G
Sbjct: 6 WKPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGL 65
Query: 274 RSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIY 333
++L+ G +L+ A IK Y+ +KRL E + ++ G L+G I+ +
Sbjct: 66 KALYSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVICGILSGVISSTIAN 125
Query: 334 PMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYE- 392
P +VLK RM + GM+ I +EG +KG G++L VY+
Sbjct: 126 PTDVLKIRMQAQSNTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDI 185
Query: 393 TLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVT 452
T K+ L ++ CG G LAS P+ +VRTRM Q +
Sbjct: 186 TKKHLILSGLMGDTVYTHFLSSFTCG----LAGALASNPVDVVRTRMMNQRVLRDGRCSG 241
Query: 453 MSSLFKHILRT---EGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 495
+ +L+T EG F LY+G PN++++ P I +V YE LK
Sbjct: 242 YTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLK 287
Score = 30.4 bits (67), Expect = 3.9
Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 9/91 (9%)
Query: 221 WRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFT-------QMIREGGA 273
+ H ++ G + P+D ++ M R G G+T Q + G
Sbjct: 201 YTHFLSSFTCGLAGALASNPVDVVRTRMM--NQRVLRDGRCSGYTGTLDCLLQTWKNEGF 258
Query: 274 RSLWRGNGINVLKIAPESAIKFMAYEQIKRL 304
+L++G N L++ P + I F+ YEQ+K+L
Sbjct: 259 FALYKGFWPNWLRLGPWNIIFFVTYEQLKKL 289
>gi|82775373 solute carrier family 25, member 37 [Homo sapiens]
Length = 338
Score = 93.2 bits (230), Expect = 5e-19
Identities = 73/288 (25%), Positives = 131/288 (45%), Gaps = 20/288 (6%)
Query: 223 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHAS--RSNNMGIVGGFTQMIREGGARSLWRGN 280
H+ AG AG + + P+D +K MQ + ++ I G +++R G RG
Sbjct: 48 HMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGV 107
Query: 281 GINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERL---VAGSLAGAIAQSSIYPMEV 337
+ ++ P A+ F YE +KR + +D + + L +AGS+A + + + P EV
Sbjct: 108 NVMIMGAGPAHAMYFACYENMKRTL-NDVFHHQGNSHLANGIAGSMATLLHDAVMNPAEV 166
Query: 338 LKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNA 397
+K R+ + + Q+ + C R + EG+ AFY+ Y + IP+ I YE L+
Sbjct: 167 VKQRLQMYNS-QHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQ 225
Query: 398 WLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQ-------ASIEGAPE 450
H N + G ++ A+ PL + +T + Q A+I G
Sbjct: 226 VNPHRTYNPQSH-----IISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLS 280
Query: 451 VTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITL 498
M++ F+ + + G G ++G+ + +P+ +IS+ VYE K L
Sbjct: 281 -GMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFL 327
Score = 58.2 bits (139), Expect = 2e-08
Identities = 46/188 (24%), Positives = 82/188 (43%), Gaps = 15/188 (7%)
Query: 314 IHERLVAGSLAGAIAQSSIYPMEVLKTRM---ALRKTGQYSGMLDCARRILAREGVAAFY 370
+ + AG++AG + S +YP++ +KTRM + QY+ + ++I+ EG
Sbjct: 45 VSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPL 104
Query: 371 KGYVPNMLGIIPYAGIDLAVYETLK---NAWLQHYAVNSADPGVFVLLACGTMSSTCGQL 427
+G ++G P + A YE +K N H + G+ G+M++
Sbjct: 105 RGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGI-----AGSMATLLHDA 159
Query: 428 ASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSIS 487
P +V+ R+Q + + + S + + RTEG YR IP SI
Sbjct: 160 VMNPAEVVKQRLQ----MYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIH 215
Query: 488 YVVYENLK 495
++ YE L+
Sbjct: 216 FITYEFLQ 223
>gi|45237193 solute carrier family 25, member 44 isoform 1 [Homo
sapiens]
Length = 314
Score = 92.8 bits (229), Expect = 6e-19
Identities = 71/299 (23%), Positives = 129/299 (43%), Gaps = 34/299 (11%)
Query: 221 WRHL------VAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGAR 274
W HL V G + R P ++ +QV +S G F +++R G
Sbjct: 12 WEHLDKKKFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILRADGIT 71
Query: 275 SLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYP 334
L+RG +N + YE ++ V ++ + + LVAG A +AQS P
Sbjct: 72 GLYRGFLVNTFTLISGQCY-VTTYELTRKFVADYSQSNTV-KSLVAGGSASLVAQSITVP 129
Query: 335 MEVLKTRMALRKTGQYSGML------------------DCARRILAREGVAAFYKGYVPN 376
++V+ + +++ G+ G D R+IL +G+ FY+GYV +
Sbjct: 130 IDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDIIRQILQADGLRGFYRGYVAS 189
Query: 377 MLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVR 436
+L IP + + Y A Y P + G +++ + + P+ ++R
Sbjct: 190 LLTYIPNSAVWWPFYHFY--AEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIR 247
Query: 437 TRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 495
TR+Q +EG + ++ F+ ++ EG +GL +GL+ + P+ + V YE+LK
Sbjct: 248 TRVQ----VEGKNSIILT--FRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLK 300
Score = 59.3 bits (142), Expect = 8e-09
Identities = 56/206 (27%), Positives = 95/206 (46%), Gaps = 26/206 (12%)
Query: 222 RHLVAGGGAGAVSRTCTAPLDRLK--VLMQVHASRSNNMGIVGG---------------F 264
+ LVAGG A V+++ T P+D + ++MQ + + G
Sbjct: 111 KSLVAGGSASLVAQSITVPIDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDII 170
Query: 265 TQMIREGGARSLWRGNGINVLKIAPESAIKFMAY----EQIKRLVGSDQETLRIHERLVA 320
Q+++ G R +RG ++L P SA+ + Y EQ+ L +E I + V+
Sbjct: 171 RQILQADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYLC--PKECPHIVFQAVS 228
Query: 321 GSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGI 380
G LA A A PM+V++TR+ + G+ S +L R+++A EG KG ++
Sbjct: 229 GPLAAATASILTNPMDVIRTRVQVE--GKNSIILTF-RQLMAEEGPWGLMKGLSARIISA 285
Query: 381 IPYAGIDLAVYETLKNAWLQHYAVNS 406
P + + YE+LK L+ V+S
Sbjct: 286 TPSTIVIVVGYESLKKLSLRPELVDS 311
>gi|149274643 solute carrier family 25, member 28 [Homo sapiens]
Length = 364
Score = 92.0 bits (227), Expect = 1e-18
Identities = 77/289 (26%), Positives = 126/289 (43%), Gaps = 29/289 (10%)
Query: 223 HLVAGGGAGAVSRTCTAPLDRLKVLMQV----HASRSNNMGIVGGFTQMIREGGARSLWR 278
H+VAG AG + P+D +K MQ A+R N ++ ++IR G R
Sbjct: 75 HMVAGAVAGILEHCVMYPIDCVKTRMQSLQPDPAARYRN--VLEALWRIIRTEGLWRPMR 132
Query: 279 GNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIH---ERLVAGSLAGAIA----QSS 331
G + P A+ F YE++K+ + IH +A AG +A ++
Sbjct: 133 GLNVTATGAGPAHALYFACYEKLKKTLSDV-----IHPGGNSHIANGAAGCVATLLHDAA 187
Query: 332 IYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVY 391
+ P EV+K RM + + Y + DC R + EG AFY+ Y + +P+ I Y
Sbjct: 188 MNPAEVVKQRMQMYNS-PYHRVTDCVRAVWQNEGAGAFYRSYTTQLTMNVPFQAIHFMTY 246
Query: 392 ETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEV 451
E L+ + N P VL G + A+ PL + +T + Q S+ +
Sbjct: 247 EFLQEHFNPQRRYN---PSSHVL--SGACAGAVAAAATTPLDVCKTLLNTQESLALNSHI 301
Query: 452 T-----MSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 495
T M+S F+ + + G +RG+ + IP+ +I++ VYE K
Sbjct: 302 TGHITGMASAFRTVYQVGGVTAYFRGVQARVIYQIPSTAIAWSVYEFFK 350
Score = 57.8 bits (138), Expect = 2e-08
Identities = 51/205 (24%), Positives = 85/205 (41%), Gaps = 13/205 (6%)
Query: 306 GSDQETL----RIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRK---TGQYSGMLDCAR 358
G D E L + +VAG++AG + +YP++ +KTRM + +Y +L+
Sbjct: 60 GPDYEALPAGATVTTHMVAGAVAGILEHCVMYPIDCVKTRMQSLQPDPAARYRNVLEALW 119
Query: 359 RILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACG 418
RI+ EG+ +G G P + A YE LK ++ A G
Sbjct: 120 RIIRTEGLWRPMRGLNVTATGAGPAHALYFACYEKLKKTLSD--VIHPGGNSHIANGAAG 177
Query: 419 TMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFM 478
+++ A P +V+ RMQ S P ++ + + + EGA YR
Sbjct: 178 CVATLLHDAAMNPAEVVKQRMQMYNS----PYHRVTDCVRAVWQNEGAGAFYRSYTTQLT 233
Query: 479 KVIPAVSISYVVYENLKITLGVQSR 503
+P +I ++ YE L+ Q R
Sbjct: 234 MNVPFQAIHFMTYEFLQEHFNPQRR 258
Score = 50.1 bits (118), Expect = 5e-06
Identities = 33/98 (33%), Positives = 46/98 (46%), Gaps = 7/98 (7%)
Query: 223 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMI-------REGGARS 275
H+++G AGAV+ T PLD K L+ S + N I G T M + GG +
Sbjct: 264 HVLSGACAGAVAAAATTPLDVCKTLLNTQESLALNSHITGHITGMASAFRTVYQVGGVTA 323
Query: 276 LWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLR 313
+RG V+ P +AI + YE K L+ QE R
Sbjct: 324 YFRGVQARVIYQIPSTAIAWSVYEFFKYLITKRQEEWR 361
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,415,915
Number of Sequences: 37866
Number of extensions: 813803
Number of successful extensions: 4488
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 140
Number of HSP's successfully gapped in prelim test: 93
Number of HSP's that attempted gapping in prelim test: 3382
Number of HSP's gapped (non-prelim): 593
length of query: 503
length of database: 18,247,518
effective HSP length: 107
effective length of query: 396
effective length of database: 14,195,856
effective search space: 5621558976
effective search space used: 5621558976
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.