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Search of human proteins with 56606061
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|56606061 translocase of inner mitochondrial membrane 22
homolog [Homo sapiens]
(194 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|56606061 translocase of inner mitochondrial membrane 22 homol... 392 e-109
gi|5454120 translocase of inner mitochondrial membrane 17 homolo... 45 3e-05
gi|5032181 translocase of inner mitochondrial membrane 17 homolo... 42 3e-04
gi|5454122 translocase of inner mitochondrial membrane 23 (yeast... 38 0.005
gi|239744083 PREDICTED: hypothetical protein XP_002343027 isofor... 38 0.005
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens] 32 0.34
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 31 0.58
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 31 0.58
gi|79750944 ubiquitin specific peptidase 42 [Homo sapiens] 31 0.76
gi|239744085 PREDICTED: hypothetical protein XP_002343028 isofor... 29 2.2
gi|66392157 RGD motif, leucine rich repeats, tropomodulin domain... 29 2.2
gi|109255251 loricrin [Homo sapiens] 29 2.9
gi|5031757 T-cell leukemia homeobox 1 [Homo sapiens] 29 2.9
gi|153792604 protein prenyltransferase alpha subunit repeat cont... 28 3.7
gi|23943912 phosphoinositide-3-kinase, regulatory subunit 4 [Hom... 28 4.9
gi|28269681 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, ... 28 6.4
gi|205277396 dynactin 1 isoform 4 [Homo sapiens] 27 8.4
gi|205277392 dynactin 1 isoform 3 [Homo sapiens] 27 8.4
gi|13259508 dynactin 1 isoform 2 [Homo sapiens] 27 8.4
gi|13259510 dynactin 1 isoform 1 [Homo sapiens] 27 8.4
>gi|56606061 translocase of inner mitochondrial membrane 22 homolog
[Homo sapiens]
Length = 194
Score = 392 bits (1007), Expect = e-109
Identities = 194/194 (100%), Positives = 194/194 (100%)
Query: 1 MAAAAPNAGGSAPETAGSAEAPLQYSLLLQYLVGDKRQPRLLEPGSLGGIPSPAKSEEQK 60
MAAAAPNAGGSAPETAGSAEAPLQYSLLLQYLVGDKRQPRLLEPGSLGGIPSPAKSEEQK
Sbjct: 1 MAAAAPNAGGSAPETAGSAEAPLQYSLLLQYLVGDKRQPRLLEPGSLGGIPSPAKSEEQK 60
Query: 61 MIEKAMESCAFKAALACVGGFVLGGAFGVFTAGIDTNVGFDPKDPYRTPTAKEVLKDMGQ 120
MIEKAMESCAFKAALACVGGFVLGGAFGVFTAGIDTNVGFDPKDPYRTPTAKEVLKDMGQ
Sbjct: 61 MIEKAMESCAFKAALACVGGFVLGGAFGVFTAGIDTNVGFDPKDPYRTPTAKEVLKDMGQ 120
Query: 121 RGMSYAKNFAIVGAMFSCTECLIESYRGTSDWKNSVISGCITGGAIGFRAGLKAGAIGCG 180
RGMSYAKNFAIVGAMFSCTECLIESYRGTSDWKNSVISGCITGGAIGFRAGLKAGAIGCG
Sbjct: 121 RGMSYAKNFAIVGAMFSCTECLIESYRGTSDWKNSVISGCITGGAIGFRAGLKAGAIGCG 180
Query: 181 GFAAFSAAIDYYLR 194
GFAAFSAAIDYYLR
Sbjct: 181 GFAAFSAAIDYYLR 194
>gi|5454120 translocase of inner mitochondrial membrane 17 homolog A
[Homo sapiens]
Length = 171
Score = 45.4 bits (106), Expect = 3e-05
Identities = 36/123 (29%), Positives = 50/123 (40%), Gaps = 5/123 (4%)
Query: 61 MIEKAMESCAFKAALACVGGFVLGGAFGVFTAGIDTNVGFDPKDPYRTPTAKEVLKDMGQ 120
M E A E C ++ C G F +G G I GF + L +
Sbjct: 1 MEEYAREPCPWRIVDDCGGAFTMGTIGGGIFQAIK---GFRNSPVGVNHRLRGSLTAIKT 57
Query: 121 RGMSYAKNFAIVGAMFSCTECLIESYRGTSDWKNSVISGCITGGAIGFRAGLKA--GAIG 178
R +FA+ G +FS +C + RG D NS+ SG +TG + R G A G+
Sbjct: 58 RAPQLGGSFAVWGGLFSMIDCSMVQVRGKEDPWNSITSGALTGAILAARNGPVAMVGSAA 117
Query: 179 CGG 181
GG
Sbjct: 118 MGG 120
>gi|5032181 translocase of inner mitochondrial membrane 17 homolog B
[Homo sapiens]
Length = 172
Score = 42.4 bits (98), Expect = 3e-04
Identities = 32/115 (27%), Positives = 49/115 (42%), Gaps = 11/115 (9%)
Query: 61 MIEKAMESCAFKAALACVGGFVLG----GAFGVFTAGIDTNVGFDPKDPYRTPTAKEVLK 116
M E A E C ++ C G F +G G F + VG +R + ++
Sbjct: 1 MEEYAREPCPWRIVDDCGGAFTMGVIGGGVFQAIKGFRNAPVGIR----HRLRGSANAVR 56
Query: 117 DMGQRGMSYAKNFAIVGAMFSCTECLIESYRGTSDWKNSVISGCITGGAIGFRAG 171
R +FA+ G +FS +C + RG D NS+ SG +TG + R+G
Sbjct: 57 I---RAPQIGGSFAVWGGLFSTIDCGLVRLRGKEDPWNSITSGALTGAVLAARSG 108
>gi|5454122 translocase of inner mitochondrial membrane 23 (yeast)
homolog [Homo sapiens]
Length = 209
Score = 38.1 bits (87), Expect = 0.005
Identities = 28/109 (25%), Positives = 48/109 (44%), Gaps = 2/109 (1%)
Query: 71 FKAALACVGGFVL-GGAFGVFTAGIDTNVGFDPKDPYRTPTAKEVLKDMGQRGMSYAKNF 129
F+ A +GG + G AFG G+ + + P ++L + ++G +A
Sbjct: 73 FELAFFTIGGCCMTGAAFGAMN-GLRLGLKETQNMAWSKPRNVQILNMVTRQGALWANTL 131
Query: 130 AIVGAMFSCTECLIESYRGTSDWKNSVISGCITGGAIGFRAGLKAGAIG 178
+ ++S +IE RG D N+V +G +TG GL+ A G
Sbjct: 132 GSLALLYSAFGVIIEKTRGAEDDLNTVAAGTMTGMLYKCTGGLRGIARG 180
>gi|239744083 PREDICTED: hypothetical protein XP_002343027 isoform 1
[Homo sapiens]
Length = 209
Score = 38.1 bits (87), Expect = 0.005
Identities = 28/109 (25%), Positives = 48/109 (44%), Gaps = 2/109 (1%)
Query: 71 FKAALACVGGFVL-GGAFGVFTAGIDTNVGFDPKDPYRTPTAKEVLKDMGQRGMSYAKNF 129
F+ A +GG + G AFG G+ + + P ++L + ++G +A
Sbjct: 73 FELAFFTIGGCCMTGAAFGAMN-GLRLGLKETQNMAWSKPRNVQILNMVTRQGALWANTL 131
Query: 130 AIVGAMFSCTECLIESYRGTSDWKNSVISGCITGGAIGFRAGLKAGAIG 178
+ ++S +IE RG D N+V +G +TG GL+ A G
Sbjct: 132 GSLALLYSAFGVIIEKTRGAEDDLNTVAAGTMTGMLYKCTGGLRGIARG 180
>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
Length = 2240
Score = 32.0 bits (71), Expect = 0.34
Identities = 22/58 (37%), Positives = 30/58 (51%), Gaps = 5/58 (8%)
Query: 2 AAAAPNAGGSAPETAGSAEAPLQYSLLLQYLVGDKR--QPRLLE-PGSLGGIPSPAKS 56
AAAA A S +A +PL++ +LQ L G K+ P E PGS G+P K+
Sbjct: 1293 AAAASTAASSTASSASKTASPLEH--ILQTLFGKKKSFDPSAREPPGSTAGLPQEPKT 1348
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 31.2 bits (69), Expect = 0.58
Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 4/47 (8%)
Query: 25 YSLLLQYLVGDKRQPRLLEPGSLGGIPSPAK----SEEQKMIEKAME 67
+ +L +Y VGD Q LL+PG + SPA EE++++ +E
Sbjct: 1728 FGILKEYEVGDPGQRTLLDPGRFSKVSSPAPMEGGEEEEELLGPKLE 1774
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 31.2 bits (69), Expect = 0.58
Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 4/47 (8%)
Query: 25 YSLLLQYLVGDKRQPRLLEPGSLGGIPSPAK----SEEQKMIEKAME 67
+ +L +Y VGD Q LL+PG + SPA EE++++ +E
Sbjct: 1511 FGILKEYEVGDPGQRTLLDPGRFSKVSSPAPMEGGEEEEELLGPKLE 1557
>gi|79750944 ubiquitin specific peptidase 42 [Homo sapiens]
Length = 1316
Score = 30.8 bits (68), Expect = 0.76
Identities = 16/43 (37%), Positives = 21/43 (48%)
Query: 32 LVGDKRQPRLLEPGSLGGIPSPAKSEEQKMIEKAMESCAFKAA 74
+VGD P L +PGSL G SP + + MI + A A
Sbjct: 809 IVGDTAPPDLCDPGSLTGDASPLSQDAKGMIAEGPRDSALAEA 851
>gi|239744085 PREDICTED: hypothetical protein XP_002343028 isoform 2
[Homo sapiens]
Length = 172
Score = 29.3 bits (64), Expect = 2.2
Identities = 17/57 (29%), Positives = 26/57 (45%)
Query: 122 GMSYAKNFAIVGAMFSCTECLIESYRGTSDWKNSVISGCITGGAIGFRAGLKAGAIG 178
G +A + ++S +IE RG D N+V +G +TG GL+ A G
Sbjct: 87 GALWANTLGSLALLYSAFGVIIEKTRGAEDDLNTVAAGTMTGMLYKCTGGLRGIARG 143
>gi|66392157 RGD motif, leucine rich repeats, tropomodulin domain
and proline-rich containing [Homo sapiens]
Length = 1435
Score = 29.3 bits (64), Expect = 2.2
Identities = 13/26 (50%), Positives = 17/26 (65%)
Query: 35 DKRQPRLLEPGSLGGIPSPAKSEEQK 60
D +P LLEPG L G+ P + EE+K
Sbjct: 912 DGGEPSLLEPGELEGLFFPEEKEEEK 937
>gi|109255251 loricrin [Homo sapiens]
Length = 312
Score = 28.9 bits (63), Expect = 2.9
Identities = 22/65 (33%), Positives = 29/65 (44%), Gaps = 2/65 (3%)
Query: 129 FAIVGAMFSCTECLIESYRGTSDWKNSVI-SGCIT-GGAIGFRAGLKAGAIGCGGFAAFS 186
F+ G FS +SY G S +S SGC + GG G G G GCGG ++
Sbjct: 144 FSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGG 203
Query: 187 AAIDY 191
+ Y
Sbjct: 204 SGSGY 208
>gi|5031757 T-cell leukemia homeobox 1 [Homo sapiens]
Length = 330
Score = 28.9 bits (63), Expect = 2.9
Identities = 12/27 (44%), Positives = 15/27 (55%)
Query: 159 GCITGGAIGFRAGLKAGAIGCGGFAAF 185
GC+ GGA + G A A G GG A+
Sbjct: 48 GCLVGGAYTYGGGGSAAATGAGGAGAY 74
>gi|153792604 protein prenyltransferase alpha subunit repeat
containing 1 [Homo sapiens]
Length = 402
Score = 28.5 bits (62), Expect = 3.7
Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 3/52 (5%)
Query: 18 SAEAPLQYSLLLQYLVGDKRQPRLLEPGSLGGIPSPAKSEEQKMIEKAMESC 69
S E + +LQ L+ + P + G+LG IP+ Q++I++ ME C
Sbjct: 136 SPETWIHRRWVLQQLIQETSLPSFVTKGNLGTIPT---ERAQRLIQEEMEVC 184
>gi|23943912 phosphoinositide-3-kinase, regulatory subunit 4 [Homo
sapiens]
Length = 1358
Score = 28.1 bits (61), Expect = 4.9
Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 9/57 (15%)
Query: 83 LGGAFGVFTAGIDTNVGFDPKDPYRTPTAKEVLKDMGQRGMSYAKNFAIVGAMFSCT 139
L GAF G+ VG+ + +LK + Q+G+S A+ F IV A+++ T
Sbjct: 593 LRGAFFDSIVGVAAYVGWQ---------SSSILKPLLQQGLSDAEEFVIVKALYALT 640
>gi|28269681 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11,
14.7kDa [Homo sapiens]
Length = 141
Score = 27.7 bits (60), Expect = 6.4
Identities = 22/64 (34%), Positives = 27/64 (42%), Gaps = 4/64 (6%)
Query: 125 YAKNFAIVGAMFSCTECLIESYR-GTSDWKNSVISGCITGGAIGFRA---GLKAGAIGCG 180
Y A VGA+F T C+ R D N + GC G +G R G+ A A
Sbjct: 59 YTFTAAAVGAVFGLTTCISAHVREKPDDPLNYFLGGCAGGLTLGARTHNYGIGAAACVYF 118
Query: 181 GFAA 184
G AA
Sbjct: 119 GIAA 122
>gi|205277396 dynactin 1 isoform 4 [Homo sapiens]
Length = 1139
Score = 27.3 bits (59), Expect = 8.4
Identities = 22/78 (28%), Positives = 36/78 (46%), Gaps = 15/78 (19%)
Query: 2 AAAAPNAGGSAPETAGSAEAPLQYSLLLQYLVGDKRQPRLLEPGSLGGIPSPAKSEE--- 58
+A+A S P T A+ PL ++ P L PG++ +PSP+K EE
Sbjct: 38 SASAGELSSSEPSTP--AQTPLAAPII--------PTPVLTSPGAVPPLPSPSKEEEGLR 87
Query: 59 --QKMIEKAMESCAFKAA 74
+ +E+ +E+ K A
Sbjct: 88 AQVRDLEEKLETLRLKRA 105
>gi|205277392 dynactin 1 isoform 3 [Homo sapiens]
Length = 1253
Score = 27.3 bits (59), Expect = 8.4
Identities = 22/78 (28%), Positives = 36/78 (46%), Gaps = 15/78 (19%)
Query: 2 AAAAPNAGGSAPETAGSAEAPLQYSLLLQYLVGDKRQPRLLEPGSLGGIPSPAKSEE--- 58
+A+A S P T A+ PL ++ P L PG++ +PSP+K EE
Sbjct: 152 SASAGELSSSEPSTP--AQTPLAAPII--------PTPVLTSPGAVPPLPSPSKEEEGLR 201
Query: 59 --QKMIEKAMESCAFKAA 74
+ +E+ +E+ K A
Sbjct: 202 AQVRDLEEKLETLRLKRA 219
>gi|13259508 dynactin 1 isoform 2 [Homo sapiens]
Length = 1144
Score = 27.3 bits (59), Expect = 8.4
Identities = 22/78 (28%), Positives = 36/78 (46%), Gaps = 15/78 (19%)
Query: 2 AAAAPNAGGSAPETAGSAEAPLQYSLLLQYLVGDKRQPRLLEPGSLGGIPSPAKSEE--- 58
+A+A S P T A+ PL ++ P L PG++ +PSP+K EE
Sbjct: 38 SASAGELSSSEPSTP--AQTPLAAPII--------PTPVLTSPGAVPPLPSPSKEEEGLR 87
Query: 59 --QKMIEKAMESCAFKAA 74
+ +E+ +E+ K A
Sbjct: 88 AQVRDLEEKLETLRLKRA 105
>gi|13259510 dynactin 1 isoform 1 [Homo sapiens]
Length = 1278
Score = 27.3 bits (59), Expect = 8.4
Identities = 22/78 (28%), Positives = 36/78 (46%), Gaps = 15/78 (19%)
Query: 2 AAAAPNAGGSAPETAGSAEAPLQYSLLLQYLVGDKRQPRLLEPGSLGGIPSPAKSEE--- 58
+A+A S P T A+ PL ++ P L PG++ +PSP+K EE
Sbjct: 172 SASAGELSSSEPSTP--AQTPLAAPII--------PTPVLTSPGAVPPLPSPSKEEEGLR 221
Query: 59 --QKMIEKAMESCAFKAA 74
+ +E+ +E+ K A
Sbjct: 222 AQVRDLEEKLETLRLKRA 239
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.136 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,859,075
Number of Sequences: 37866
Number of extensions: 351687
Number of successful extensions: 1078
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1058
Number of HSP's gapped (non-prelim): 25
length of query: 194
length of database: 18,247,518
effective HSP length: 97
effective length of query: 97
effective length of database: 14,574,516
effective search space: 1413728052
effective search space used: 1413728052
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.