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Search of human proteins with 55749577
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55749577 solute carrier family 25 (mitochondrial carrier;
adenine nucleotide translocator), member 4 [Homo sapiens]
(298 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55749577 solute carrier family 25 (mitochondrial carrier; ade... 605 e-173
gi|156071459 solute carrier family 25, member 5 [Homo sapiens] 548 e-156
gi|156071462 solute carrier family 25, member A6 [Homo sapiens] 547 e-156
gi|13775208 solute carrier family 25 (mitochondrial carrier; ade... 437 e-123
gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo ... 131 8e-31
gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo s... 131 8e-31
gi|60460887 solute carrier family 25, member 42 [Homo sapiens] 120 1e-27
gi|48476342 solute carrier family 25, member 23 [Homo sapiens] 115 6e-26
gi|21361103 solute carrier family 25, member 12 [Homo sapiens] 114 1e-25
gi|239755176 PREDICTED: similar to solute carrier family 25, mem... 113 2e-25
gi|239755174 PREDICTED: similar to solute carrier family 25, mem... 113 2e-25
gi|56699407 solute carrier family 25, member 25 isoform c [Homo ... 113 2e-25
gi|56699401 solute carrier family 25, member 25 isoform a [Homo ... 113 2e-25
gi|56699405 solute carrier family 25, member 25 isoform d [Homo ... 113 2e-25
gi|56699403 solute carrier family 25, member 25 isoform b [Homo ... 113 2e-25
gi|27544933 solute carrier family 25, member 16 [Homo sapiens] 111 7e-25
gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo s... 110 2e-24
gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo... 110 2e-24
gi|149274607 solute carrier family 25, member 41 [Homo sapiens] 107 1e-23
gi|21687151 mitochondrial solute carrier protein [Homo sapiens] 104 1e-22
gi|58197562 solute carrier family 25, member 30 [Homo sapiens] 101 9e-22
gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Ho... 99 3e-21
gi|13259543 solute carrier family 25, member 14 isoform UCP5S [H... 99 3e-21
gi|21314739 solute carrier family 25, member 32 [Homo sapiens] 99 6e-21
gi|13899342 solute carrier [Homo sapiens] 97 1e-20
gi|4507807 uncoupling protein 3 isoform UCP3L [Homo sapiens] 91 9e-19
gi|108860679 solute carrier family 25, member 27 [Homo sapiens] 90 3e-18
gi|13259541 uncoupling protein 2 [Homo sapiens] 89 6e-18
gi|13449279 solute carrier family 25 (mitochondrial oxodicarboxy... 89 6e-18
gi|186928856 solute carrier family 25, member 19 [Homo sapiens] 87 2e-17
>gi|55749577 solute carrier family 25 (mitochondrial carrier;
adenine nucleotide translocator), member 4 [Homo
sapiens]
Length = 298
Score = 605 bits (1560), Expect = e-173
Identities = 298/298 (100%), Positives = 298/298 (100%)
Query: 1 MGDHAWSFLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVR 60
MGDHAWSFLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVR
Sbjct: 1 MGDHAWSFLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVR 60
Query: 61 IPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASG 120
IPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASG
Sbjct: 61 IPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASG 120
Query: 121 GAAGATSLCFVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVS 180
GAAGATSLCFVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVS
Sbjct: 121 GAAGATSLCFVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVS 180
Query: 181 VQGIIIYRAAYFGVYDTAKGMLPDPKNVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMM 240
VQGIIIYRAAYFGVYDTAKGMLPDPKNVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMM
Sbjct: 181 VQGIIIYRAAYFGVYDTAKGMLPDPKNVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMM 240
Query: 241 QSGRKGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGMGGAFVLVLYDEIKKYV 298
QSGRKGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGMGGAFVLVLYDEIKKYV
Sbjct: 241 QSGRKGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGMGGAFVLVLYDEIKKYV 298
>gi|156071459 solute carrier family 25, member 5 [Homo sapiens]
Length = 298
Score = 548 bits (1413), Expect = e-156
Identities = 265/297 (89%), Positives = 281/297 (94%)
Query: 1 MGDHAWSFLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVR 60
M D A SF KDFLAGGVAAA+SKTAVAPIERVKLLLQVQHASKQI+A+KQYKGIIDCVVR
Sbjct: 1 MTDAAVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVR 60
Query: 61 IPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASG 120
IPKEQG LSFWRGNLANVIRYFPTQALNFAFKDKYKQ+FLGGVD+ QFW YFAGNLASG
Sbjct: 61 IPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASG 120
Query: 121 GAAGATSLCFVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVS 180
GAAGATSLCFVYPLDFARTRLAADVGK A+REF GLGDC++KI+KSDG++GLYQGFNVS
Sbjct: 121 GAAGATSLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVS 180
Query: 181 VQGIIIYRAAYFGVYDTAKGMLPDPKNVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMM 240
VQGIIIYRAAYFG+YDTAKGMLPDPKN HI +SWMIAQ+VTAVAGL SYPFDTVRRRMMM
Sbjct: 181 VQGIIIYRAAYFGIYDTAKGMLPDPKNTHIVISWMIAQTVTAVAGLTSYPFDTVRRRMMM 240
Query: 241 QSGRKGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGMGGAFVLVLYDEIKKY 297
QSGRKG DIMYTGT+DCWRKIA+DEG KAFFKGAWSNVLRGMGGAFVLVLYDEIKKY
Sbjct: 241 QSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGGAFVLVLYDEIKKY 297
>gi|156071462 solute carrier family 25, member A6 [Homo sapiens]
Length = 298
Score = 547 bits (1409), Expect = e-156
Identities = 263/298 (88%), Positives = 282/298 (94%)
Query: 1 MGDHAWSFLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVR 60
M + A SF KDFLAGG+AAA+SKTAVAPIERVKLLLQVQHASKQI+A+KQYKGI+DC+VR
Sbjct: 1 MTEQAISFAKDFLAGGIAAAISKTAVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVR 60
Query: 61 IPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASG 120
IPKEQG LSFWRGNLANVIRYFPTQALNFAFKDKYKQ+FLGGVD+H QFWRYFAGNLASG
Sbjct: 61 IPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKHTQFWRYFAGNLASG 120
Query: 121 GAAGATSLCFVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVS 180
GAAGATSLCFVYPLDFARTRLAADVGK +REF GLGDC++KI KSDG+RGLYQGF+VS
Sbjct: 121 GAAGATSLCFVYPLDFARTRLAADVGKSGTEREFRGLGDCLVKITKSDGIRGLYQGFSVS 180
Query: 181 VQGIIIYRAAYFGVYDTAKGMLPDPKNVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMM 240
VQGIIIYRAAYFGVYDTAKGMLPDPKN HI VSWMIAQ+VTAVAG+VSYPFDTVRRRMMM
Sbjct: 181 VQGIIIYRAAYFGVYDTAKGMLPDPKNTHIVVSWMIAQTVTAVAGVVSYPFDTVRRRMMM 240
Query: 241 QSGRKGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGMGGAFVLVLYDEIKKYV 298
QSGRKGADIMYTGTVDCWRKI +DEG KAFFKGAWSNVLRGMGGAFVLVLYDE+KK +
Sbjct: 241 QSGRKGADIMYTGTVDCWRKIFRDEGGKAFFKGAWSNVLRGMGGAFVLVLYDELKKVI 298
>gi|13775208 solute carrier family 25 (mitochondrial carrier;
adenine nucleotide translocator), member 31 [Homo
sapiens]
Length = 315
Score = 437 bits (1123), Expect = e-123
Identities = 216/293 (73%), Positives = 247/293 (84%), Gaps = 2/293 (0%)
Query: 5 AWSFLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKE 64
A SF KD LAGGVAAAVSKTAVAPIERVKLLLQVQ +SKQIS E +YKG++DC+VRIP+E
Sbjct: 17 ASSFGKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPRE 76
Query: 65 QGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAG 124
QGF SFWRGNLANVIRYFPTQALNFAFKDKYKQLF+ GV++ KQFWR+F NLASGGAAG
Sbjct: 77 QGFFSFWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAG 136
Query: 125 ATSLCFVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGI 184
ATSLC VYPLDFARTRL D+GKG +R+F GLGDCI+KI KSDG+ GLYQGF VSVQGI
Sbjct: 137 ATSLCVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGI 196
Query: 185 IIYRAAYFGVYDTAKGMLPDPKNVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGR 244
I+YRA+YFG YDT KG+LP PK VS+ IAQ VT +G++SYPFDTVRRRMMMQSG
Sbjct: 197 IVYRASYFGAYDTVKGLLPKPKKTPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQSGE 256
Query: 245 KGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGMGGAFVLVLYDEIKKY 297
A Y GT+DC+ KI + EG +FF+GA+SNVLRG GGA VLVLYD+IK++
Sbjct: 257 --AKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLRGTGGALVLVLYDKIKEF 307
>gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo
sapiens]
Length = 477
Score = 131 bits (329), Expect = 8e-31
Identities = 93/293 (31%), Positives = 147/293 (50%), Gaps = 24/293 (8%)
Query: 10 KDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLS 69
+ LAGG+A AVS+T+ AP++R+K+++QV H SK I ++ KE G S
Sbjct: 196 RQLLAGGIAGAVSRTSTAPLDRLKIMMQV-HGSKS-----DKMNIFGGFRQMVKEGGIRS 249
Query: 70 FWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLC 129
WRGN NVI+ P A+ F ++YK+L + F R+ +G++ AGAT+
Sbjct: 250 LWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSM-----AGATAQT 304
Query: 130 FVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYRA 189
F+YP++ +TRLA VGK ++ G+ DC KI K +GL Y+G+ ++ GII Y
Sbjct: 305 FIYPMEVMKTRLA--VGKTG---QYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAG 359
Query: 190 AYFGVYDTAK-----GMLPDPKNVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGR 244
VY+ K D N + V + L SYP VR RM Q+
Sbjct: 360 IDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAML 419
Query: 245 KGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGMGGAFV-LVLYDEIKK 296
+G+ + V +R+I EG ++G N ++ + + V+Y+ +K+
Sbjct: 420 EGSPQL--NMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQ 470
Score = 64.3 bits (155), Expect = 1e-10
Identities = 51/195 (26%), Positives = 86/195 (44%), Gaps = 18/195 (9%)
Query: 12 FLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSFW 71
F++G +A A ++T + P+E +K L V QY GI DC +I K +G +F+
Sbjct: 292 FISGSMAGATAQTFIYPMEVMKTRLAVGKTG-------QYSGIYDCAKKILKHEGLGAFY 344
Query: 72 RGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLC-- 129
+G + N++ P ++ A + K +L + G + G +S C
Sbjct: 345 KGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDS----VNPGVMVLLGCGALSSTCGQ 400
Query: 130 -FVYPLDFARTRLAADVG-KGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIY 187
YPL RTR+ A +G+ Q GL +I +G+ GLY+G + ++
Sbjct: 401 LASYPLALVRTRMQAQAMLEGSPQLNMVGL---FRRIISKEGIPGLYRGITPNFMKVLPA 457
Query: 188 RAAYFGVYDTAKGML 202
+ VY+ K L
Sbjct: 458 VGISYVVYENMKQTL 472
>gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo
sapiens]
Length = 458
Score = 131 bits (329), Expect = 8e-31
Identities = 93/293 (31%), Positives = 147/293 (50%), Gaps = 24/293 (8%)
Query: 10 KDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLS 69
+ LAGG+A AVS+T+ AP++R+K+++QV H SK I ++ KE G S
Sbjct: 177 RQLLAGGIAGAVSRTSTAPLDRLKIMMQV-HGSKS-----DKMNIFGGFRQMVKEGGIRS 230
Query: 70 FWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLC 129
WRGN NVI+ P A+ F ++YK+L + F R+ +G++ AGAT+
Sbjct: 231 LWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSM-----AGATAQT 285
Query: 130 FVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYRA 189
F+YP++ +TRLA VGK ++ G+ DC KI K +GL Y+G+ ++ GII Y
Sbjct: 286 FIYPMEVMKTRLA--VGKTG---QYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAG 340
Query: 190 AYFGVYDTAK-----GMLPDPKNVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGR 244
VY+ K D N + V + L SYP VR RM Q+
Sbjct: 341 IDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAML 400
Query: 245 KGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGMGGAFV-LVLYDEIKK 296
+G+ + V +R+I EG ++G N ++ + + V+Y+ +K+
Sbjct: 401 EGSPQL--NMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQ 451
Score = 64.3 bits (155), Expect = 1e-10
Identities = 51/195 (26%), Positives = 86/195 (44%), Gaps = 18/195 (9%)
Query: 12 FLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSFW 71
F++G +A A ++T + P+E +K L V QY GI DC +I K +G +F+
Sbjct: 273 FISGSMAGATAQTFIYPMEVMKTRLAVGKTG-------QYSGIYDCAKKILKHEGLGAFY 325
Query: 72 RGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLC-- 129
+G + N++ P ++ A + K +L + G + G +S C
Sbjct: 326 KGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDS----VNPGVMVLLGCGALSSTCGQ 381
Query: 130 -FVYPLDFARTRLAADVG-KGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIY 187
YPL RTR+ A +G+ Q GL +I +G+ GLY+G + ++
Sbjct: 382 LASYPLALVRTRMQAQAMLEGSPQLNMVGL---FRRIISKEGIPGLYRGITPNFMKVLPA 438
Query: 188 RAAYFGVYDTAKGML 202
+ VY+ K L
Sbjct: 439 VGISYVVYENMKQTL 453
>gi|60460887 solute carrier family 25, member 42 [Homo sapiens]
Length = 318
Score = 120 bits (302), Expect = 1e-27
Identities = 90/283 (31%), Positives = 139/283 (49%), Gaps = 31/283 (10%)
Query: 9 LKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFL 68
L L G +A A++KTAVAP++R K++ QV +SK+ SA++ ++ + + +GFL
Sbjct: 34 LSSLLPGALAGALAKTAVAPLDRTKIIFQV--SSKRFSAKEAFRVLYYTYLN----EGFL 87
Query: 69 SFWRGNLANVIRYFPTQALNFAFKDKYKQL---FLGGVDRHKQFW-RYFAGNLASGGAAG 124
S WRGN A ++R P A+ F+ ++YK++ + G W R FAG L AG
Sbjct: 88 SLWRGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGAL-----AG 142
Query: 125 ATSLCFVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGI 184
T+ YPLD R R+A + + + I+I + +GL+ LY GF +V G+
Sbjct: 143 TTAASLTYPLDLVRARMAV-----TPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGV 197
Query: 185 IIYRAAYFGVYDTAKGM---LPDPKNVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQ 241
I Y F Y+T K + + + F + + SYP D VRRRM
Sbjct: 198 IPYAGLSFFTYETLKSLHREYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVRRRMQTA 257
Query: 242 --SGRKGADIMYTGTVDCWRKIAKDEGA-KAFFKGAWSNVLRG 281
+G A I T R I ++EGA + +KG N ++G
Sbjct: 258 GVTGYPRASIART-----LRTIVREEGAVRGLYKGLSMNWVKG 295
Score = 43.1 bits (100), Expect = 3e-04
Identities = 43/182 (23%), Positives = 75/182 (41%), Gaps = 22/182 (12%)
Query: 107 KQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFK 166
K+ R +L G AGA + V PLD + + +A+ F + +
Sbjct: 27 KRDHRQVLSSLLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFR----VLYYTYL 82
Query: 167 SDGLRGLYQGFNVSVQGIIIYRAAYFGVYDTAKGMLPD---------PKNVHIFVSWMIA 217
++G L++G + ++ ++ Y A F ++ K +L P +F A
Sbjct: 83 NEGFLSLWRGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAG---A 139
Query: 218 QSVTAVAGLVSYPFDTVRRRMMMQSGRKGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSN 277
+ T A L +YP D VR RM + MY+ + +I+++EG K + G
Sbjct: 140 LAGTTAASL-TYPLDLVRARMAVTPKE-----MYSNIFHVFIRISREEGLKTLYHGFMPT 193
Query: 278 VL 279
VL
Sbjct: 194 VL 195
>gi|48476342 solute carrier family 25, member 23 [Homo sapiens]
Length = 468
Score = 115 bits (287), Expect = 6e-26
Identities = 87/293 (29%), Positives = 138/293 (47%), Gaps = 24/293 (8%)
Query: 10 KDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLS 69
K +AG VA AVS+T AP++R+K+ +QV HASK I+ + + E G S
Sbjct: 187 KQLVAGAVAGAVSRTGTAPLDRLKVFMQV-HASK-----TNRLNILGGLRSMVLEGGIRS 240
Query: 70 FWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLC 129
WRGN NV++ P A+ F ++ K+ LG + R+ AG+L AGAT+
Sbjct: 241 LWRGNGINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQERFVAGSL-----AGATAQT 295
Query: 130 FVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYRA 189
+YP++ +TRL ++ GL DC +I + +G R Y+G+ +V GII Y
Sbjct: 296 IIYPMEVLKTRLTL-----RRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAG 350
Query: 190 AYFGVYDTAKG-----MLPDPKNVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGR 244
VY+T K D + I V + + SYP VR RM Q+
Sbjct: 351 IDLAVYETLKNWWLQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASI 410
Query: 245 KGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGMGGAFV-LVLYDEIKK 296
+G + + R I EG + ++G N ++ + + V+Y+ +K+
Sbjct: 411 EGGPQL--SMLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQ 461
Score = 73.2 bits (178), Expect = 3e-13
Identities = 56/192 (29%), Positives = 88/192 (45%), Gaps = 12/192 (6%)
Query: 12 FLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSFW 71
F+AG +A A ++T + P+E +K L ++ QYKG++DC RI + +G +F+
Sbjct: 283 FVAGSLAGATAQTIIYPMEVLKTRLTLRRTG-------QYKGLLDCARRILEREGPRAFY 335
Query: 72 RGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLCFV 131
RG L NV+ P ++ A + K +L H LA G +
Sbjct: 336 RGYLPNVLGIIPYAGIDLAVYETLKNWWLQQYS-HDSADPGILVLLACGTISSTCGQIAS 394
Query: 132 YPLDFARTRLAADVG-KGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYRAA 190
YPL RTR+ A +G Q GL + I +G+RGLY+G + +I +
Sbjct: 395 YPLALVRTRMQAQASIEGGPQLSMLGL---LRHILSQEGMRGLYRGIAPNFMKVIPAVSI 451
Query: 191 YFGVYDTAKGML 202
+ VY+ K L
Sbjct: 452 SYVVYENMKQAL 463
>gi|21361103 solute carrier family 25, member 12 [Homo sapiens]
Length = 678
Score = 114 bits (285), Expect = 1e-25
Identities = 88/295 (29%), Positives = 135/295 (45%), Gaps = 29/295 (9%)
Query: 12 FLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSFW 71
F G VA AV TAV PI+ VK +Q Q S + E YK DC ++ + +GF +
Sbjct: 330 FTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLY 389
Query: 72 RGNLANVIRYFPTQALNFAFKDKYKQLFL---GGVDRHKQFWRYFAGNLASGGAAGATSL 128
RG + +I P +A+ D + F G V + +GG AG + +
Sbjct: 390 RGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVP--------LPAEVLAGGCAGGSQV 441
Query: 129 CFVYPLDFARTRL--AADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIII 186
F PL+ + RL A ++ G + L D G+ GLY+G I
Sbjct: 442 IFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDL--------GIFGLYKGAKACFLRDIP 493
Query: 187 YRAAYFGVYDTAKGMLPDPKNVHIFVSWMIAQSVTA---VAGLVSYPFDTVRRRMMMQSG 243
+ A YF VY K +L D +N H+ ++A A A LV+ P D ++ R +Q
Sbjct: 494 FSAIYFPVYAHCKLLLAD-ENGHVGGLNLLAAGAMAGVPAASLVT-PADVIKTR--LQVA 549
Query: 244 RKGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGMGG-AFVLVLYDEIKKY 297
+ Y+G +DC+RKI ++EG AF+KG + V R LV Y+ ++++
Sbjct: 550 ARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQRW 604
Score = 48.5 bits (114), Expect = 7e-06
Identities = 46/172 (26%), Positives = 70/172 (40%), Gaps = 27/172 (15%)
Query: 11 DFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSF 70
+ LAGG A P+E VK+ LQV A + G + + ++ G
Sbjct: 429 EVLAGGCAGGSQVIFTNPLEIVKIRLQV--------AGEITTGPRVSALNVLRDLGIFGL 480
Query: 71 WRGNLANVIRYFPTQALNFAFKDKYKQLF------LGGVDRHKQFWRYFAGNLASGGAAG 124
++G A +R P A+ F K L +GG++ LA+G AG
Sbjct: 481 YKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNL-----------LAAGAMAG 529
Query: 125 ATSLCFVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQG 176
+ V P D +TRL V A Q + G+ DC KI + +G ++G
Sbjct: 530 VPAASLVTPADVIKTRL--QVAARAGQTTYSGVIDCFRKILREEGPSAFWKG 579
>gi|239755176 PREDICTED: similar to solute carrier family 25, member
25 isoform 2 [Homo sapiens]
Length = 469
Score = 113 bits (282), Expect = 2e-25
Identities = 84/292 (28%), Positives = 143/292 (48%), Gaps = 24/292 (8%)
Query: 10 KDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLS 69
+ +AGG A AVS+T AP++R+K+L+QV HAS+ GI+ ++ +E G S
Sbjct: 188 RHLVAGGGAGAVSRTCTAPLDRLKVLMQV-HASR-----SNNMGIVGGFTQMIREGGARS 241
Query: 70 FWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLC 129
WRGN NV++ P A+ F ++ K+L + + R AG+L AGA +
Sbjct: 242 LWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSL-----AGAIAQS 296
Query: 130 FVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYRA 189
+YP++ +TR+A ++ G+ DC +I +G+ Y+G+ ++ GII Y
Sbjct: 297 SIYPMEVLKTRMAL-----RKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 351
Query: 190 AYFGVYDTAKGMLPDPKNVH-----IFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGR 244
VY+T K V+ +FV + L SYP VR RM Q+
Sbjct: 352 IDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASI 411
Query: 245 KGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGMGGAFV-LVLYDEIK 295
+GA + ++ ++ I + EGA ++G N ++ + + V+Y+ +K
Sbjct: 412 EGAPEVTMSSL--FKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
>gi|239755174 PREDICTED: similar to solute carrier family 25, member
25 isoform 1 [Homo sapiens]
Length = 503
Score = 113 bits (282), Expect = 2e-25
Identities = 84/292 (28%), Positives = 143/292 (48%), Gaps = 24/292 (8%)
Query: 10 KDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLS 69
+ +AGG A AVS+T AP++R+K+L+QV HAS+ GI+ ++ +E G S
Sbjct: 222 RHLVAGGGAGAVSRTCTAPLDRLKVLMQV-HASR-----SNNMGIVGGFTQMIREGGARS 275
Query: 70 FWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLC 129
WRGN NV++ P A+ F ++ K+L + + R AG+L AGA +
Sbjct: 276 LWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSL-----AGAIAQS 330
Query: 130 FVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYRA 189
+YP++ +TR+A ++ G+ DC +I +G+ Y+G+ ++ GII Y
Sbjct: 331 SIYPMEVLKTRMAL-----RKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 385
Query: 190 AYFGVYDTAKGMLPDPKNVH-----IFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGR 244
VY+T K V+ +FV + L SYP VR RM Q+
Sbjct: 386 IDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASI 445
Query: 245 KGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGMGGAFV-LVLYDEIK 295
+GA + ++ ++ I + EGA ++G N ++ + + V+Y+ +K
Sbjct: 446 EGAPEVTMSSL--FKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 495
>gi|56699407 solute carrier family 25, member 25 isoform c [Homo
sapiens]
Length = 489
Score = 113 bits (282), Expect = 2e-25
Identities = 84/292 (28%), Positives = 143/292 (48%), Gaps = 24/292 (8%)
Query: 10 KDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLS 69
+ +AGG A AVS+T AP++R+K+L+QV HAS+ GI+ ++ +E G S
Sbjct: 208 RHLVAGGGAGAVSRTCTAPLDRLKVLMQV-HASR-----SNNMGIVGGFTQMIREGGARS 261
Query: 70 FWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLC 129
WRGN NV++ P A+ F ++ K+L + + R AG+L AGA +
Sbjct: 262 LWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSL-----AGAIAQS 316
Query: 130 FVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYRA 189
+YP++ +TR+A ++ G+ DC +I +G+ Y+G+ ++ GII Y
Sbjct: 317 SIYPMEVLKTRMAL-----RKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 371
Query: 190 AYFGVYDTAKGMLPDPKNVH-----IFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGR 244
VY+T K V+ +FV + L SYP VR RM Q+
Sbjct: 372 IDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASI 431
Query: 245 KGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGMGGAFV-LVLYDEIK 295
+GA + ++ ++ I + EGA ++G N ++ + + V+Y+ +K
Sbjct: 432 EGAPEVTMSSL--FKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 481
>gi|56699401 solute carrier family 25, member 25 isoform a [Homo
sapiens]
Length = 469
Score = 113 bits (282), Expect = 2e-25
Identities = 84/292 (28%), Positives = 143/292 (48%), Gaps = 24/292 (8%)
Query: 10 KDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLS 69
+ +AGG A AVS+T AP++R+K+L+QV HAS+ GI+ ++ +E G S
Sbjct: 188 RHLVAGGGAGAVSRTCTAPLDRLKVLMQV-HASR-----SNNMGIVGGFTQMIREGGARS 241
Query: 70 FWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLC 129
WRGN NV++ P A+ F ++ K+L + + R AG+L AGA +
Sbjct: 242 LWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSL-----AGAIAQS 296
Query: 130 FVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYRA 189
+YP++ +TR+A ++ G+ DC +I +G+ Y+G+ ++ GII Y
Sbjct: 297 SIYPMEVLKTRMAL-----RKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 351
Query: 190 AYFGVYDTAKGMLPDPKNVH-----IFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGR 244
VY+T K V+ +FV + L SYP VR RM Q+
Sbjct: 352 IDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASI 411
Query: 245 KGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGMGGAFV-LVLYDEIK 295
+GA + ++ ++ I + EGA ++G N ++ + + V+Y+ +K
Sbjct: 412 EGAPEVTMSSL--FKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
>gi|56699405 solute carrier family 25, member 25 isoform d [Homo
sapiens]
Length = 366
Score = 113 bits (282), Expect = 2e-25
Identities = 84/292 (28%), Positives = 143/292 (48%), Gaps = 24/292 (8%)
Query: 10 KDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLS 69
+ +AGG A AVS+T AP++R+K+L+QV HAS+ GI+ ++ +E G S
Sbjct: 85 RHLVAGGGAGAVSRTCTAPLDRLKVLMQV-HASR-----SNNMGIVGGFTQMIREGGARS 138
Query: 70 FWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLC 129
WRGN NV++ P A+ F ++ K+L + + R AG+L AGA +
Sbjct: 139 LWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSL-----AGAIAQS 193
Query: 130 FVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYRA 189
+YP++ +TR+A ++ G+ DC +I +G+ Y+G+ ++ GII Y
Sbjct: 194 SIYPMEVLKTRMAL-----RKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 248
Query: 190 AYFGVYDTAKGMLPDPKNVH-----IFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGR 244
VY+T K V+ +FV + L SYP VR RM Q+
Sbjct: 249 IDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASI 308
Query: 245 KGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGMGGAFV-LVLYDEIK 295
+GA + ++ ++ I + EGA ++G N ++ + + V+Y+ +K
Sbjct: 309 EGAPEVTMSSL--FKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 358
>gi|56699403 solute carrier family 25, member 25 isoform b [Homo
sapiens]
Length = 503
Score = 113 bits (282), Expect = 2e-25
Identities = 84/292 (28%), Positives = 143/292 (48%), Gaps = 24/292 (8%)
Query: 10 KDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLS 69
+ +AGG A AVS+T AP++R+K+L+QV HAS+ GI+ ++ +E G S
Sbjct: 222 RHLVAGGGAGAVSRTCTAPLDRLKVLMQV-HASR-----SNNMGIVGGFTQMIREGGARS 275
Query: 70 FWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLC 129
WRGN NV++ P A+ F ++ K+L + + R AG+L AGA +
Sbjct: 276 LWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSL-----AGAIAQS 330
Query: 130 FVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYRA 189
+YP++ +TR+A ++ G+ DC +I +G+ Y+G+ ++ GII Y
Sbjct: 331 SIYPMEVLKTRMAL-----RKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 385
Query: 190 AYFGVYDTAKGMLPDPKNVH-----IFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGR 244
VY+T K V+ +FV + L SYP VR RM Q+
Sbjct: 386 IDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASI 445
Query: 245 KGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGMGGAFV-LVLYDEIK 295
+GA + ++ ++ I + EGA ++G N ++ + + V+Y+ +K
Sbjct: 446 EGAPEVTMSSL--FKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 495
>gi|27544933 solute carrier family 25, member 16 [Homo sapiens]
Length = 332
Score = 111 bits (278), Expect = 7e-25
Identities = 79/251 (31%), Positives = 121/251 (48%), Gaps = 34/251 (13%)
Query: 8 FLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGF 67
+L+ FLAGG+A +KT VAP++RVK+LLQ + ++ G+ + +P+++GF
Sbjct: 36 WLRSFLAGGIAGCCAKTTVAPLDRVKVLLQAH------NHHYKHLGVFSALRAVPQKEGF 89
Query: 68 LSFWRGNLANVIRYFPTQALNFAFKDKYKQLFLG--GVDRHKQFWRYFAGNLASGGAAGA 125
L ++GN A +IR FP A+ F + YK L G+ H L +G AG
Sbjct: 90 LGLYKGNGAMMIRIFPYGAIQFMAFEHYKTLITTKLGISGH-------VHRLMAGSMAGM 142
Query: 126 TSLCFVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIF-KSDGLRGLYQGFNVSVQGI 184
T++ YPLD R RLA V KG + + G+ I+ K G G Y+G ++ G+
Sbjct: 143 TAVICTYPLDMVRVRLAFQV-KG--EHSYTGIIHAFKTIYAKEGGFFGFYRGLMPTILGM 199
Query: 185 IIYRAAYFGVYDTAKGM----------LPDPKNVHIF-----VSWMIAQSVTAVAGLVSY 229
Y F + T K + P N ++ V+ + A+A +SY
Sbjct: 200 APYAGVSFFTFGTLKSVGLSHAPTLLGRPSSDNPNVLVLKTHVNLLCGGVAGAIAQTISY 259
Query: 230 PFDTVRRRMMM 240
PFD RRRM +
Sbjct: 260 PFDVTRRRMQL 270
Score = 52.4 bits (124), Expect = 5e-07
Identities = 47/181 (25%), Positives = 82/181 (45%), Gaps = 11/181 (6%)
Query: 101 GGVDRHKQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKGAAQREFHGLGDC 160
GG + F Y+ + +GG AG + V PLD + L A + G+
Sbjct: 26 GGPTTRRDF--YWLRSFLAGGIAGCCAKTTVAPLDRVKVLLQAH----NHHYKHLGVFSA 79
Query: 161 IIKIFKSDGLRGLYQGFNVSVQGIIIYRAAYFGVYDTAKGMLPDPKNVHIFVSWMIAQSV 220
+ + + +G GLY+G + I Y A F ++ K ++ + V ++A S+
Sbjct: 80 LRAVPQKEGFLGLYKGNGAMMIRIFPYGAIQFMAFEHYKTLITTKLGISGHVHRLMAGSM 139
Query: 221 TAVAGLV-SYPFDTVRRRMMMQSGRKGADIMYTGTVDCWRKI-AKDEGAKAFFKGAWSNV 278
+ ++ +YP D VR R+ Q KG + YTG + ++ I AK+ G F++G +
Sbjct: 140 AGMTAVICTYPLDMVRVRLAFQV--KG-EHSYTGIIHAFKTIYAKEGGFFGFYRGLMPTI 196
Query: 279 L 279
L
Sbjct: 197 L 197
Score = 52.4 bits (124), Expect = 5e-07
Identities = 52/201 (25%), Positives = 80/201 (39%), Gaps = 23/201 (11%)
Query: 13 LAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRI-PKEQGFLSFW 71
+AG +A + P++ V++ L Q + E Y GII I KE GF F+
Sbjct: 135 MAGSMAGMTAVICTYPLDMVRVRLAFQ-----VKGEHSYTGIIHAFKTIYAKEGGFFGFY 189
Query: 72 RGNLANVIRYFPTQALNFAFKDKYKQLFLGGV---------DRHKQFWRYFAGNLASGGA 122
RG + ++ P ++F K + L D NL GG
Sbjct: 190 RGLMPTILGMAPYAGVSFFTFGTLKSVGLSHAPTLLGRPSSDNPNVLVLKTHVNLLCGGV 249
Query: 123 AGATSLCFVYPLDFARTRLAADVGKGAAQREFHG---LGDCIIKIFKSDGLR-GLYQGFN 178
AGA + YP D R R+ G EF + D + ++ G+R GLY+G +
Sbjct: 250 AGAIAQTISYPFDVTRRRMQL----GTVLPEFEKCLTMRDTMKYVYGHHGIRKGLYRGLS 305
Query: 179 VSVQGIIIYRAAYFGVYDTAK 199
++ I +A F Y+ K
Sbjct: 306 LNYIRCIPSQAVAFTTYELMK 326
Score = 29.6 bits (65), Expect = 3.4
Identities = 23/90 (25%), Positives = 41/90 (45%), Gaps = 4/90 (4%)
Query: 11 DFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLS- 69
+ L GGVA A+++T P + + +Q+ + ++ + D + + G
Sbjct: 243 NLLCGGVAGAIAQTISYPFDVTRRRMQLGTVLPEF---EKCLTMRDTMKYVYGHHGIRKG 299
Query: 70 FWRGNLANVIRYFPTQALNFAFKDKYKQLF 99
+RG N IR P+QA+ F + KQ F
Sbjct: 300 LYRGLSLNYIRCIPSQAVAFTTYELMKQFF 329
>gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo
sapiens]
Length = 675
Score = 110 bits (274), Expect = 2e-24
Identities = 78/273 (28%), Positives = 125/273 (45%), Gaps = 20/273 (7%)
Query: 12 FLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSFW 71
F G VA AV TAV PI+ VK +Q Q ++ E YK DC ++ + +GF +
Sbjct: 332 FGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLY 391
Query: 72 RGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLCFV 131
RG L ++ P +A+ D + F+ HK A + +GG AG + + F
Sbjct: 392 RGLLPQLLGVAPEKAIKLTVNDFVRDKFM-----HKDGSVPLAAEILAGGCAGGSQVIFT 446
Query: 132 YPLDFARTRL--AADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYRA 189
PL+ + RL A ++ G + + + G G+Y+G I + A
Sbjct: 447 NPLEIVKIRLQVAGEITTGPRV--------SALSVVRDLGFFGIYKGAKACFLRDIPFSA 498
Query: 190 AYFGVYDTAKGMLPDPKNVHIFVSWMIAQSVTAV--AGLVSYPFDTVRRRMMMQSGRKGA 247
YF Y K + S ++A ++ + A LV+ P D ++ R +Q +
Sbjct: 499 IYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVT-PADVIKTR--LQVAARAG 555
Query: 248 DIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLR 280
Y+G +DC+RKI ++EG KA +KGA + V R
Sbjct: 556 QTTYSGVIDCFRKILREEGPKALWKGAGARVFR 588
Score = 52.0 bits (123), Expect = 6e-07
Identities = 48/172 (27%), Positives = 72/172 (41%), Gaps = 17/172 (9%)
Query: 11 DFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSF 70
+ LAGG A P+E VK+ LQV A + G + + ++ GF
Sbjct: 431 EILAGGCAGGSQVIFTNPLEIVKIRLQV--------AGEITTGPRVSALSVVRDLGFFGI 482
Query: 71 WRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGA-AGATSLC 129
++G A +R P A+ F K F + + G+L GA AG +
Sbjct: 483 YKGAKACFLRDIPFSAIYFPCYAHVKASFA------NEDGQVSPGSLLLAGAIAGMPAAS 536
Query: 130 FVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSV 181
V P D +TRL V A Q + G+ DC KI + +G + L++G V
Sbjct: 537 LVTPADVIKTRL--QVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARV 586
Score = 45.4 bits (106), Expect = 6e-05
Identities = 29/94 (30%), Positives = 46/94 (48%), Gaps = 7/94 (7%)
Query: 13 LAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSFWR 72
LAG +A + + V P + +K LQV + Q + Y G+IDC +I +E+G + W+
Sbjct: 525 LAGAIAGMPAASLVTPADVIKTRLQVAARAGQTT----YSGVIDCFRKILREEGPKALWK 580
Query: 73 GNLANVIR---YFPTQALNFAFKDKYKQLFLGGV 103
G A V R F L + ++ + GGV
Sbjct: 581 GAGARVFRSSPQFGVTLLTYELLQRWFYIDFGGV 614
>gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo
sapiens]
Length = 676
Score = 110 bits (274), Expect = 2e-24
Identities = 78/273 (28%), Positives = 125/273 (45%), Gaps = 20/273 (7%)
Query: 12 FLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSFW 71
F G VA AV TAV PI+ VK +Q Q ++ E YK DC ++ + +GF +
Sbjct: 333 FGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLY 392
Query: 72 RGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLCFV 131
RG L ++ P +A+ D + F+ HK A + +GG AG + + F
Sbjct: 393 RGLLPQLLGVAPEKAIKLTVNDFVRDKFM-----HKDGSVPLAAEILAGGCAGGSQVIFT 447
Query: 132 YPLDFARTRL--AADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYRA 189
PL+ + RL A ++ G + + + G G+Y+G I + A
Sbjct: 448 NPLEIVKIRLQVAGEITTGPRV--------SALSVVRDLGFFGIYKGAKACFLRDIPFSA 499
Query: 190 AYFGVYDTAKGMLPDPKNVHIFVSWMIAQSVTAV--AGLVSYPFDTVRRRMMMQSGRKGA 247
YF Y K + S ++A ++ + A LV+ P D ++ R +Q +
Sbjct: 500 IYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVT-PADVIKTR--LQVAARAG 556
Query: 248 DIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLR 280
Y+G +DC+RKI ++EG KA +KGA + V R
Sbjct: 557 QTTYSGVIDCFRKILREEGPKALWKGAGARVFR 589
Score = 52.0 bits (123), Expect = 6e-07
Identities = 48/172 (27%), Positives = 72/172 (41%), Gaps = 17/172 (9%)
Query: 11 DFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSF 70
+ LAGG A P+E VK+ LQV A + G + + ++ GF
Sbjct: 432 EILAGGCAGGSQVIFTNPLEIVKIRLQV--------AGEITTGPRVSALSVVRDLGFFGI 483
Query: 71 WRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGA-AGATSLC 129
++G A +R P A+ F K F + + G+L GA AG +
Sbjct: 484 YKGAKACFLRDIPFSAIYFPCYAHVKASFA------NEDGQVSPGSLLLAGAIAGMPAAS 537
Query: 130 FVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSV 181
V P D +TRL V A Q + G+ DC KI + +G + L++G V
Sbjct: 538 LVTPADVIKTRL--QVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARV 587
Score = 45.4 bits (106), Expect = 6e-05
Identities = 29/94 (30%), Positives = 46/94 (48%), Gaps = 7/94 (7%)
Query: 13 LAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSFWR 72
LAG +A + + V P + +K LQV + Q + Y G+IDC +I +E+G + W+
Sbjct: 526 LAGAIAGMPAASLVTPADVIKTRLQVAARAGQTT----YSGVIDCFRKILREEGPKALWK 581
Query: 73 GNLANVIR---YFPTQALNFAFKDKYKQLFLGGV 103
G A V R F L + ++ + GGV
Sbjct: 582 GAGARVFRSSPQFGVTLLTYELLQRWFYIDFGGV 615
>gi|149274607 solute carrier family 25, member 41 [Homo sapiens]
Length = 370
Score = 107 bits (268), Expect = 1e-23
Identities = 84/299 (28%), Positives = 139/299 (46%), Gaps = 33/299 (11%)
Query: 6 WSFLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQ 65
W FL L+G +A AVS+T AP++R K+ +QV S++ + ++ + + +E
Sbjct: 93 WKFL---LSGAMAGAVSRTGTAPLDRAKVYMQVY------SSKTNFTNLLGGLQSMVQEG 143
Query: 66 GFLSFWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGA 125
GF S WRGN NV++ P A+ F+ ++ K F G Q F L +G A A
Sbjct: 144 GFRSLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCG-----IQGSPPFQERLLAGSLAVA 198
Query: 126 TSLCFVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGII 185
S + P++ +TRL ++ GL DC +I + +G R LY+G+ ++ GII
Sbjct: 199 ISQTLINPMEVLKTRLTL-----RRTGQYKGLLDCARQILQREGTRALYRGYLPNMLGII 253
Query: 186 IYRAAYFGVYDTAKGM-------LPDPKNVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRM 238
Y VY+ + + DP + VS T + SYP VR RM
Sbjct: 254 PYACTDLAVYEMLQCFWVKSGRDMGDPSGL---VSLSSVTLSTTCGQMASYPLTLVRTRM 310
Query: 239 MMQSGRKGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGM-GGAFVLVLYDEIKK 296
Q +G++ G + ++I +G ++G +L+ + G V+Y+ +KK
Sbjct: 311 QAQDTVEGSNPTMRGVL---QRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKK 366
Score = 59.7 bits (143), Expect = 3e-09
Identities = 53/206 (25%), Positives = 89/206 (43%), Gaps = 34/206 (16%)
Query: 8 FLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGF 67
F + LAG +A A+S+T + P+E +K L ++ QYKG++DC +I + +G
Sbjct: 186 FQERLLAGSLAVAISQTLINPMEVLKTRLTLRRTG-------QYKGLLDCARQILQREGT 238
Query: 68 LSFWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATS 127
+ +RG L N++ P + A Y+ L + FW ++ G +G S
Sbjct: 239 RALYRGYLPNMLGIIPYACTDLAV---YEML--------QCFWVKSGRDM--GDPSGLVS 285
Query: 128 LCFV-----------YPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQG 176
L V YPL RTR+ A + G+ + +I G GLY+G
Sbjct: 286 LSSVTLSTTCGQMASYPLTLVRTRMQAQDTVEGSNPTMRGV---LQRILAQQGWLGLYRG 342
Query: 177 FNVSVQGIIIYRAAYFGVYDTAKGML 202
++ ++ + VY+ K L
Sbjct: 343 MTPTLLKVLPAGGISYVVYEAMKKTL 368
>gi|21687151 mitochondrial solute carrier protein [Homo sapiens]
Length = 341
Score = 104 bits (259), Expect = 1e-22
Identities = 76/276 (27%), Positives = 129/276 (46%), Gaps = 25/276 (9%)
Query: 13 LAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSFWR 72
L G+A +S + AP+E +L QV +G R+ + +G + W+
Sbjct: 17 LCAGLAGTLSLSLTAPLELATVLAQVG------VVRGHARGPWATGHRVWRAEGLRALWK 70
Query: 73 GNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLCFVY 132
GN +R FP A+ A K+ LF + Q+ AG+L AG S Y
Sbjct: 71 GNAVACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSL-----AGMVSTIVTY 125
Query: 133 PLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYRAAYF 192
P D +TRL + + + + GL I++ +G LY+G +++V G + + A
Sbjct: 126 PTDLIKTRL---IMQNILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAGSL 182
Query: 193 GVYDTAKGMLPDPKN----VHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQS----GR 244
VY + + P++ F + +A +VT +S+PF+TV+R+M QS
Sbjct: 183 LVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVTQT---LSFPFETVKRKMQAQSPYLPHS 239
Query: 245 KGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLR 280
G D+ ++G VDC+R+I K +G + G +N+L+
Sbjct: 240 GGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLK 275
Score = 58.9 bits (141), Expect = 5e-09
Identities = 46/198 (23%), Positives = 84/198 (42%), Gaps = 17/198 (8%)
Query: 6 WSFLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQ 65
WS + +AG +A VS P + +K L +Q+ E Y+G++ I +++
Sbjct: 107 WSSI---MAGSLAGMVSTIVTYPTDLIKTRLIMQNI-----LEPSYRGLLHAFSTIYQQE 158
Query: 66 GFLSFWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGA 125
GFL+ +RG V+ P A + ++++ G D+ N A+ A A
Sbjct: 159 GFLALYRGVSLTVVGALPFSAGSLLVYMNLEKIWNGPRDQFS-----LPQNFANVCLAAA 213
Query: 126 TSLCFVYPLDFARTRLAADVG----KGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSV 181
+ +P + + ++ A G F G DC +I K+ G+ GL+ G ++
Sbjct: 214 VTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANL 273
Query: 182 QGIIIYRAAYFGVYDTAK 199
I+ Y F ++ K
Sbjct: 274 LKIVPYFGIMFSTFEFCK 291
Score = 47.0 bits (110), Expect = 2e-05
Identities = 29/97 (29%), Positives = 49/97 (50%), Gaps = 2/97 (2%)
Query: 6 WSFLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQ--HASKQISAEKQYKGIIDCVVRIPK 63
+S ++F +AAAV++T P E VK +Q Q + + + G +DC +I K
Sbjct: 199 FSLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVK 258
Query: 64 EQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQLFL 100
QG L W G AN+++ P + F+ + K++ L
Sbjct: 259 AQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCKRICL 295
>gi|58197562 solute carrier family 25, member 30 [Homo sapiens]
Length = 291
Score = 101 bits (251), Expect = 9e-22
Identities = 83/296 (28%), Positives = 132/296 (44%), Gaps = 23/296 (7%)
Query: 10 KDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQIS-AEKQYKGIIDCVVRIPKEQGFL 68
K F+ GG+A+ ++ PI+ K LQ+Q + E +Y+G++ +VRI +E+G
Sbjct: 7 KPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLK 66
Query: 69 SFWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSL 128
+ + G ++R + K+LF ++R + N+ G +G S
Sbjct: 67 ALYSGIAPAMLRQASYGTIKIGTYQSLKRLF---IERPED--ETLPINVICGILSGVISS 121
Query: 129 CFVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYR 188
P D + R+ A G+ + I++ +G RGL++G +++ Q I
Sbjct: 122 TIANPTDVLKIRMQAQSNTIQG-----GMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVV 176
Query: 189 AAYFGVYDTAK------GMLPDPKNVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQS 242
VYD K G++ D H S+ + L S P D VR RMM Q
Sbjct: 177 GVELPVYDITKKHLILSGLMGDTVYTHFLSSFTCGLA----GALASNPVDVVRTRMMNQR 232
Query: 243 G-RKGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLR-GMGGAFVLVLYDEIKK 296
R G YTGT+DC + K+EG A +KG W N LR G V Y+++KK
Sbjct: 233 VLRDGRCSGYTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLKK 288
Score = 37.7 bits (86), Expect = 0.012
Identities = 27/101 (26%), Positives = 47/101 (46%), Gaps = 6/101 (5%)
Query: 1 MGDHAWS-FLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVV 59
MGD ++ FL F G A S P++ V+ + Q + Y G +DC++
Sbjct: 196 MGDTVYTHFLSSFTCGLAGALASN----PVDVVRTRMMNQRVLRDGRCSG-YTGTLDCLL 250
Query: 60 RIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQLFL 100
+ K +GF + ++G N +R P + F ++ K+L L
Sbjct: 251 QTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLKKLDL 291
>gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Homo
sapiens]
Length = 325
Score = 99.4 bits (246), Expect = 3e-21
Identities = 85/297 (28%), Positives = 130/297 (43%), Gaps = 26/297 (8%)
Query: 10 KDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQIS-AEKQYKGIIDCVVRIPKEQGFL 68
K F+ GG+A+ V++ P++ K LQVQ S E +Y+G+ + RI KE+G L
Sbjct: 42 KPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVL 101
Query: 69 SFWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSL 128
+ + G ++R + K+LF+ ++ N+ G +G S
Sbjct: 102 ALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLI-----NMICGVVSGVISS 156
Query: 129 CFVYPLDFARTRLAAD--VGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIII 186
P D + R+ A + +G+ F I I++ +G RGL++G + Q I
Sbjct: 157 TIANPTDVLKIRMQAQGSLFQGSMIGSF-------IDIYQQEGTRGLWRGVVPTAQRAAI 209
Query: 187 YRAAYFGVYDTAK------GMLPDPKNVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMM 240
VYD K GM+ D H S+ + L S P D VR RMM
Sbjct: 210 VVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCGLA----GALASNPVDVVRTRMMN 265
Query: 241 QSGRKGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLR-GMGGAFVLVLYDEIKK 296
Q G +Y GTVD K+ K EG A +KG W N LR G + Y+++K+
Sbjct: 266 QRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKR 322
Score = 35.8 bits (81), Expect = 0.047
Identities = 24/98 (24%), Positives = 47/98 (47%), Gaps = 5/98 (5%)
Query: 1 MGDHAWSFLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVR 60
MGD + G+A A++ P++ V+ + Q A + YKG +D +++
Sbjct: 231 MGDTILTHFVSSFTCGLAGALASN---PVDVVRTRMMNQRAI--VGHVDLYKGTVDGILK 285
Query: 61 IPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQL 98
+ K +GF + ++G N +R P + F ++ K+L
Sbjct: 286 MWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKRL 323
>gi|13259543 solute carrier family 25, member 14 isoform UCP5S [Homo
sapiens]
Length = 322
Score = 99.4 bits (246), Expect = 3e-21
Identities = 85/297 (28%), Positives = 130/297 (43%), Gaps = 26/297 (8%)
Query: 10 KDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQIS-AEKQYKGIIDCVVRIPKEQGFL 68
K F+ GG+A+ V++ P++ K LQVQ S E +Y+G+ + RI KE+G L
Sbjct: 39 KPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVL 98
Query: 69 SFWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSL 128
+ + G ++R + K+LF+ ++ N+ G +G S
Sbjct: 99 ALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLI-----NMICGVVSGVISS 153
Query: 129 CFVYPLDFARTRLAAD--VGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIII 186
P D + R+ A + +G+ F I I++ +G RGL++G + Q I
Sbjct: 154 TIANPTDVLKIRMQAQGSLFQGSMIGSF-------IDIYQQEGTRGLWRGVVPTAQRAAI 206
Query: 187 YRAAYFGVYDTAK------GMLPDPKNVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMM 240
VYD K GM+ D H S+ + L S P D VR RMM
Sbjct: 207 VVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCGLA----GALASNPVDVVRTRMMN 262
Query: 241 QSGRKGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLR-GMGGAFVLVLYDEIKK 296
Q G +Y GTVD K+ K EG A +KG W N LR G + Y+++K+
Sbjct: 263 QRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKR 319
Score = 35.8 bits (81), Expect = 0.047
Identities = 24/98 (24%), Positives = 47/98 (47%), Gaps = 5/98 (5%)
Query: 1 MGDHAWSFLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVR 60
MGD + G+A A++ P++ V+ + Q A + YKG +D +++
Sbjct: 228 MGDTILTHFVSSFTCGLAGALASN---PVDVVRTRMMNQRAI--VGHVDLYKGTVDGILK 282
Query: 61 IPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQL 98
+ K +GF + ++G N +R P + F ++ K+L
Sbjct: 283 MWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKRL 320
>gi|21314739 solute carrier family 25, member 32 [Homo sapiens]
Length = 315
Score = 98.6 bits (244), Expect = 6e-21
Identities = 84/314 (26%), Positives = 140/314 (44%), Gaps = 33/314 (10%)
Query: 2 GDHAWSFL------KDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGII 55
G AWS + ++ +AG +S A+ P++ VK+ V S + +Y GI+
Sbjct: 10 GSSAWSTVFRHVRYENLIAGVSGGVLSNLALHPLDLVKIRFAV---SDGLELRPKYNGIL 66
Query: 56 DCVVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAG 115
C+ I K G ++G N+ + L F F + K G + Y
Sbjct: 67 HCLTTIWKLDGLRGLYQGVTPNIWGAGLSWGLYFFFYNAIKSYKTEGRAERLEATEY--- 123
Query: 116 NLASGGAAGATSLCFVYPLDFARTRLAA--DVGKGAAQREFHGLGDCIIKIFKSDGLRGL 173
L S AGA +LC PL +TRL D + R++ G+ D ++KI+K +G+RGL
Sbjct: 124 -LVSAAEAGAMTLCITNPLWVTKTRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEGVRGL 182
Query: 174 YQGFNVSVQGIIIYRAAYFGVYDTAK-------GMLPDPKNVHI-FVSWMIAQSVTAVAG 225
Y+GF + G + A F Y+ K LP+ + + ++S + AVA
Sbjct: 183 YKGFVPGLFGTS-HGALQFMAYELLKLKYNQHINRLPEAQLSTVEYISVAALSKIFAVAA 241
Query: 226 LVSYPFDTVRRRMMMQSGRKGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGMGGA 285
+YP+ VR R+ Q + Y+G +D K + EG F+KG N++R
Sbjct: 242 --TYPYQVVRARLQDQH------MFYSGVIDVITKTWRKEGVGGFYKGIAPNLIRVTPAC 293
Query: 286 FV-LVLYDEIKKYV 298
+ V+Y+ + ++
Sbjct: 294 CITFVVYENVSHFL 307
Score = 43.5 bits (101), Expect = 2e-04
Identities = 42/189 (22%), Positives = 78/189 (41%), Gaps = 11/189 (5%)
Query: 18 AAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSFWRGNLAN 77
A A++ P+ K L +Q+ + S +QYKG+ D +V+I K +G ++G +
Sbjct: 130 AGAMTLCITNPLWVTKTRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEGVRGLYKGFVPG 189
Query: 78 VIRYFPTQ--ALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLCFVYPLD 135
+ F T AL F + K + ++R + ++ + ++ YP
Sbjct: 190 L---FGTSHGALQFMAYELLKLKYNQHINRLPEAQLSTVEYISVAALSKIFAVAATYPYQ 246
Query: 136 FARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYRAAYFGVY 195
R RL + G+ D I K ++ +G+ G Y+G ++ + F VY
Sbjct: 247 VVRARLQDQ------HMFYSGVIDVITKTWRKEGVGGFYKGIAPNLIRVTPACCITFVVY 300
Query: 196 DTAKGMLPD 204
+ L D
Sbjct: 301 ENVSHFLLD 309
Score = 35.4 bits (80), Expect = 0.061
Identities = 25/93 (26%), Positives = 41/93 (44%), Gaps = 12/93 (12%)
Query: 19 AAVSK----TAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSFWRGN 74
AA+SK A P + V+ LQ QH Y G+ID + + +++G F++G
Sbjct: 231 AALSKIFAVAATYPYQVVRARLQDQHMF--------YSGVIDVITKTWRKEGVGGFYKGI 282
Query: 75 LANVIRYFPTQALNFAFKDKYKQLFLGGVDRHK 107
N+IR P + F + L ++ K
Sbjct: 283 APNLIRVTPACCITFVVYENVSHFLLDLREKRK 315
>gi|13899342 solute carrier [Homo sapiens]
Length = 315
Score = 97.4 bits (241), Expect = 1e-20
Identities = 81/300 (27%), Positives = 128/300 (42%), Gaps = 44/300 (14%)
Query: 7 SFLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQG 66
S + GGVA V T V PI+ K LQ QH + YKG+IDC+++ + +G
Sbjct: 7 SITAKLINGGVAGLVGVTCVFPIDLAKTRLQNQHG------KAMYKGMIDCLMKTARAEG 60
Query: 67 FLSFWRGNLANVIRYFPTQALNFAFKDKYKQLFL-GGVDRHKQFWRYFAGNLASGGAAGA 125
F +RG N+ P +A+ A D +++L + G+ R+ + + +G AG
Sbjct: 61 FFGMYRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKM------EMLAGCGAGM 114
Query: 126 TSLCFVYPLDFARTRLAADVGK--------------------GAAQREFHGLGDCII-KI 164
+ P++ + +L D G+ G+A I ++
Sbjct: 115 CQVVVTCPMEMLKIQL-QDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWEL 173
Query: 165 FKSDGLRGLYQGFNVSVQGIIIYRAAYFGVYDTAKG-----MLPDPKNVHIFVSWMIAQS 219
++ GL GLY+G ++ I + YF ++ + H FVS +A S
Sbjct: 174 LRTQGLAGLYRGLGATLLRDIPFSIIYFPLFANLNNLGFNELAGKASFAHSFVSGCVAGS 233
Query: 220 VTAVAGLVSYPFDTVRRRMMMQSGRKGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVL 279
+ AVA P D ++ R+ G D MY+G DC RK+ EG AF KGA L
Sbjct: 234 IAAVA---VTPLDVLKTRIQTLKKGLGED-MYSGITDCARKLWIQEGPSAFMKGAGCRAL 289
>gi|4507807 uncoupling protein 3 isoform UCP3L [Homo sapiens]
Length = 312
Score = 91.3 bits (225), Expect = 9e-19
Identities = 75/296 (25%), Positives = 127/296 (42%), Gaps = 24/296 (8%)
Query: 12 FLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEK--QYKGIIDCVVRIPKEQGFLS 69
FL G AA + P++ K+ LQ+Q ++ + + QY+G++ ++ + + +G S
Sbjct: 17 FLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPCS 76
Query: 70 FWRGNLANVIRYFPTQALNFAFKDKYKQLFL-GGVDRHKQFWRYFAGNLASGGAAGATSL 128
+ G +A + R ++ D KQ++ G D R A G GA ++
Sbjct: 77 PYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRILA-----GCTTGAMAV 131
Query: 129 CFVYPLDFARTRLAADV--GKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIII 186
P D + R A + G + R++ G D I + +G+RGL++G ++ I
Sbjct: 132 TCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRNAI 191
Query: 187 YRAAYFGVYDTAKGMLPDPKNVHIFVSWMIAQSVTA-----VAGLVSYPFDTVRRRMMMQ 241
A YD K L D H+ V+A A +V+ P D V+ R M
Sbjct: 192 VNCAEVVTYDILKEKLLD---YHLLTDNFPCHFVSAFGAGFCATVVASPVDVVKTRYM-- 246
Query: 242 SGRKGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLR-GMGGAFVLVLYDEIKK 296
Y +DC K+ EG AF+KG + LR G + V Y+++K+
Sbjct: 247 ---NSPPGQYFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQLKR 299
Score = 57.8 bits (138), Expect = 1e-08
Identities = 46/190 (24%), Positives = 75/190 (39%), Gaps = 9/190 (4%)
Query: 13 LAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSFWR 72
LAG A++ T P + VK+ Q ++++Y G +D I +E+G W+
Sbjct: 121 LAGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWK 180
Query: 73 GNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLCFVY 132
G L N++R D K+ L D H F + S AG +
Sbjct: 181 GTLPNIMRNAIVNCAEVVTYDILKEKLL---DYH-LLTDNFPCHFVSAFGAGFCATVVAS 236
Query: 133 PLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYRAAYF 192
P+D +TR + ++ DC+IK+ +G Y+GF S + + F
Sbjct: 237 PVDVVKTRY-----MNSPPGQYFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMF 291
Query: 193 GVYDTAKGML 202
Y+ K L
Sbjct: 292 VTYEQLKRAL 301
Score = 35.8 bits (81), Expect = 0.047
Identities = 24/102 (23%), Positives = 47/102 (46%), Gaps = 5/102 (4%)
Query: 200 GMLPDPKNVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGRKGAD----IMYTGTV 255
G+ P + V ++ A + A LV++P DT + R+ +Q + + Y G +
Sbjct: 3 GLKPSDVPPTMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVL 62
Query: 256 DCWRKIAKDEGAKAFFKGAWSNVLRGMGGAFVLV-LYDEIKK 296
+ + EG + + G + + R M A + + LYD +K+
Sbjct: 63 GTILTMVRTEGPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQ 104
>gi|108860679 solute carrier family 25, member 27 [Homo sapiens]
Length = 323
Score = 89.7 bits (221), Expect = 3e-18
Identities = 73/305 (23%), Positives = 129/305 (42%), Gaps = 19/305 (6%)
Query: 6 WSFLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQ------HASKQISAEKQYKGIIDCVV 59
W FL G AA V++ A P++ K LQ+Q Y+G++ +
Sbjct: 17 WPRASKFLLSGCAATVAELATFPLDLTKTRLQMQGEAALARLGDGARESAPYRGMVRTAL 76
Query: 60 RIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQLFLG-GVDRHKQFWRYFAGNLA 118
I +E+GFL W+G + R+ + +++ G D H W+ G
Sbjct: 77 GIIEEEGFLKLWQGVTPAIYRHVVYSGGRMVTYEHLREVVFGKSEDEHYPLWKSVIG--- 133
Query: 119 SGGAAGATSLCFVYPLDFARTRLAADVGKGAAQRE---FHGLGDCIIKIFKSDGLRGLYQ 175
G AG P D + ++ + GK + + F G+ KI G+RGL+
Sbjct: 134 -GMMAGVIGQFLANPTDLVKVQMQME-GKRKLEGKPLRFRGVHHAFAKILAEGGIRGLWA 191
Query: 176 GFNVSVQGIIIYRAAYFGVYDTAKG--MLPDPKNVHIFVSWMIAQSVTAVAGLVSYPFDT 233
G+ ++Q + YDT K +L P +I + + VA ++ P D
Sbjct: 192 GWVPNIQRAALVNMGDLTTYDTVKHYLVLNTPLEDNIMTHGLSSLCSGLVASILGTPADV 251
Query: 234 VRRRMMMQ-SGRKGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGMGGAFVLVL-Y 291
++ R+M Q ++G ++Y + DC + + EG + +KG + LR + V L Y
Sbjct: 252 IKSRIMNQPRDKQGRGLLYKSSTDCLIQAVQGEGFMSLYKGFLPSWLRMTPWSMVFWLTY 311
Query: 292 DEIKK 296
++I++
Sbjct: 312 EKIRE 316
Score = 43.9 bits (102), Expect = 2e-04
Identities = 39/203 (19%), Positives = 76/203 (37%), Gaps = 11/203 (5%)
Query: 3 DHAWSFLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIP 62
D + K + G +A + + P + VK+ +Q++ K +++G+ +I
Sbjct: 122 DEHYPLWKSVIGGMMAGVIGQFLANPTDLVKVQMQMEGKRKLEGKPLRFRGVHHAFAKIL 181
Query: 63 KEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGA 122
E G W G + N+ R + D K + + +L SG
Sbjct: 182 AEGGIRGLWAGWVPNIQRAALVNMGDLTTYDTVKHYLVLNTPLEDNIMTHGLSSLCSGLV 241
Query: 123 AGATSLCFVYPLDFARTRLAAD----VGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFN 178
A P D ++R+ G+G + DC+I+ + +G LY+GF
Sbjct: 242 ASILGT----PADVIKSRIMNQPRDKQGRGLL---YKSSTDCLIQAVQGEGFMSLYKGFL 294
Query: 179 VSVQGIIIYRAAYFGVYDTAKGM 201
S + + ++ Y+ + M
Sbjct: 295 PSWLRMTPWSMVFWLTYEKIREM 317
>gi|13259541 uncoupling protein 2 [Homo sapiens]
Length = 309
Score = 88.6 bits (218), Expect = 6e-18
Identities = 73/295 (24%), Positives = 126/295 (42%), Gaps = 25/295 (8%)
Query: 12 FLAGGVAAAVSKTAVAPIERVKLLLQVQHASK---QISAEKQYKGIIDCVVRIPKEQGFL 68
FL G AA ++ P++ K+ LQ+Q S+ + +A QY+G++ ++ + + +G
Sbjct: 17 FLGAGTAACIADLITFPLDTAKVRLQIQGESQGPVRATASAQYRGVMGTILTMVRTEGPR 76
Query: 69 SFWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSL 128
S + G +A + R ++ D KQ + G + L +G GA ++
Sbjct: 77 SLYNGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSEHAS-----IGSRLLAGSTTGALAV 131
Query: 129 CFVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYR 188
P D + R A G +R + + I + +G RGL++G + +V I
Sbjct: 132 AVAQPTDVVKVRFQAQARAGGGRR-YQSTVNAYKTIAREEGFRGLWKGTSPNVARNAIVN 190
Query: 189 AAYFGVYDTAK------GMLPDPKNVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQS 242
A YD K ++ D H F S A T V ++ P D V+ R M
Sbjct: 191 CAELVTYDLIKDALLKANLMTDDLPCH-FTSAFGAGFCTTV---IASPVDVVKTRYM--- 243
Query: 243 GRKGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLR-GMGGAFVLVLYDEIKK 296
A Y+ C + + EG +AF+KG + LR G + V Y+++K+
Sbjct: 244 --NSALGQYSSAGHCALTMLQKEGPRAFYKGFMPSFLRLGSWNVVMFVTYEQLKR 296
Score = 53.5 bits (127), Expect = 2e-07
Identities = 43/190 (22%), Positives = 71/190 (37%), Gaps = 12/190 (6%)
Query: 13 LAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSFWR 72
LAG A++ P + VK+ Q Q + ++Y+ ++ I +E+GF W+
Sbjct: 121 LAGSTTGALAVAVAQPTDVVKVRFQAQ---ARAGGGRRYQSTVNAYKTIAREEGFRGLWK 177
Query: 73 GNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLCFVY 132
G NV R D K L +F S AG +
Sbjct: 178 GTSPNVARNAIVNCAELVTYDLIKDALLKANLMTDDLPCHFT----SAFGAGFCTTVIAS 233
Query: 133 PLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYRAAYF 192
P+D +TR +A ++ G C + + + +G R Y+GF S + + F
Sbjct: 234 PVDVVKTRYM-----NSALGQYSSAGHCALTMLQKEGPRAFYKGFMPSFLRLGSWNVVMF 288
Query: 193 GVYDTAKGML 202
Y+ K L
Sbjct: 289 VTYEQLKRAL 298
Score = 42.4 bits (98), Expect = 5e-04
Identities = 24/92 (26%), Positives = 47/92 (51%), Gaps = 6/92 (6%)
Query: 212 VSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGRKG-----ADIMYTGTVDCWRKIAKDEG 266
V ++ A + +A L+++P DT + R+ +Q +G A Y G + + + EG
Sbjct: 15 VKFLGAGTAACIADLITFPLDTAKVRLQIQGESQGPVRATASAQYRGVMGTILTMVRTEG 74
Query: 267 AKAFFKGAWSNVLRGMGGAFVLV-LYDEIKKY 297
++ + G + + R M A V + LYD +K++
Sbjct: 75 PRSLYNGLVAGLQRQMSFASVRIGLYDSVKQF 106
>gi|13449279 solute carrier family 25 (mitochondrial
oxodicarboxylate carrier), member 21 [Homo sapiens]
Length = 299
Score = 88.6 bits (218), Expect = 6e-18
Identities = 75/286 (26%), Positives = 130/286 (45%), Gaps = 14/286 (4%)
Query: 10 KDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLS 69
+ +AGG A V + P++ VK Q+Q + ++ YK ++D I + +G
Sbjct: 15 RQIVAGGSAGLVEICLMHPLDVVKTRFQIQRCATDPNS---YKSLVDSFRMIFQMEGLFG 71
Query: 70 FWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLC 129
F++G L ++ P +A+ F ++YK+L LG V AG +G T
Sbjct: 72 FYKGILPPILAETPKRAVKFFTFEQYKKL-LGYVSLSPALTFAIAGL-----GSGLTEAI 125
Query: 130 FVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYRA 189
V P + + L A+ A Q G IIK + GL+GL +G ++ ++
Sbjct: 126 VVNPFEVVKVGLQANRNTFAEQPSTVGYARQIIK-KEGWGLQGLNKGLTATLGRHGVFNM 184
Query: 190 AYFGVYDTAKGMLPDPKN--VHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGRKGA 247
YFG Y K M+P K+ + + + I +A +++ PFD + R+ G
Sbjct: 185 VYFGFYYNVKNMIPVNKDPILEFWRKFGIGLLSGTIASVINIPFDVAKSRIQGPQPVPG- 243
Query: 248 DIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLR-GMGGAFVLVLYD 292
+I Y + ++EG A +KG ++R G GGA +L++Y+
Sbjct: 244 EIKYRTCFKTMATVYQEEGILALYKGLLPKIMRLGPGGAVMLLVYE 289
>gi|186928856 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 87.0 bits (214), Expect = 2e-17
Identities = 68/293 (23%), Positives = 134/293 (45%), Gaps = 21/293 (7%)
Query: 13 LAGGVAAAVSKTAVAPIERVKLLLQVQHASKQIS-AEKQYKGIIDCVVRIPKEQGFLSFW 71
+AG V+ V++ ++P + +K+ Q+QH S +Y GI+ +I +E+G +FW
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 72 RGNLANVIRYFPTQALNF-AFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLCF 130
+G++ I A+ F +F+ + + G V ++F +F GG A +
Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFV----CGGLAACMATLT 135
Query: 131 VYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYRAA 190
V+P+D RTR AA + ++ L + +++S+G + Y+G ++ I Y
Sbjct: 136 VHPVDVLRTRFAAQ----GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGL 191
Query: 191 YFGVYDTAKGMLP-----DPKNVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGRK 245
F Y + K + + K + + ++ ++YP D ++R+ +
Sbjct: 192 QFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEH 251
Query: 246 -----GADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLR-GMGGAFVLVLYD 292
G Y G +DC +++ + EGA FFKG ++L+ + F+ Y+
Sbjct: 252 ARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
Score = 57.0 bits (136), Expect = 2e-08
Identities = 45/182 (24%), Positives = 75/182 (41%), Gaps = 12/182 (6%)
Query: 5 AWSFLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKE 64
A F F+ GG+AA ++ V P++ ++ Q K Y + V + +
Sbjct: 115 AREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQ------GEPKVYNTLRHAVGTMYRS 168
Query: 65 QGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAG 124
+G F++G +I FP L F+ K L+ + + NL G AG
Sbjct: 169 EGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQ-NLLCGSGAG 227
Query: 125 ATSLCFVYPLDFARTRLAADVGKGAAQ-----REFHGLGDCIIKIFKSDGLRGLYQGFNV 179
S YPLD + RL + A R + GL DC ++ + +G G ++G +
Sbjct: 228 VISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSP 287
Query: 180 SV 181
S+
Sbjct: 288 SL 289
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.140 0.435
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,126,749
Number of Sequences: 37866
Number of extensions: 394564
Number of successful extensions: 1397
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 865
Number of HSP's gapped (non-prelim): 185
length of query: 298
length of database: 18,247,518
effective HSP length: 102
effective length of query: 196
effective length of database: 14,385,186
effective search space: 2819496456
effective search space used: 2819496456
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.