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Search of human proteins with 5453539
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5453539 phosphoribosylaminoimidazole carboxylase,
phosphoribosylaminoimidazole succinocarboxamide synthetase isoform 2
[Homo sapiens]
(425 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|119220557 phosphoribosylaminoimidazole carboxylase, phosphori... 864 0.0
gi|5453539 phosphoribosylaminoimidazole carboxylase, phosphoribo... 864 0.0
gi|119220559 phosphoribosylaminoimidazole carboxylase, phosphori... 854 0.0
gi|148612801 KIAA1009 protein [Homo sapiens] 32 1.1
gi|118498347 DnaJ (Hsp40) homolog, subfamily C , member 25 [Homo... 32 1.4
gi|28372497 ubiquitin protein ligase E3 component n-recognin 1 [... 31 1.9
gi|61743980 stabilin 2 precursor [Homo sapiens] 30 3.2
gi|42794760 acyl-CoA synthetase long-chain family member 5 isofo... 30 4.2
gi|42794758 acyl-CoA synthetase long-chain family member 5 isofo... 30 4.2
gi|42794756 acyl-CoA synthetase long-chain family member 5 isofo... 30 4.2
gi|40805854 isthmin 2 homolog isoform 3 [Homo sapiens] 29 7.1
gi|11055992 serine carboxypeptidase 1 precursor [Homo sapiens] 29 9.3
>gi|119220557 phosphoribosylaminoimidazole carboxylase,
phosphoribosylaminoimidazole succinocarboxamide
synthetase isoform 2 [Homo sapiens]
Length = 425
Score = 864 bits (2232), Expect = 0.0
Identities = 425/425 (100%), Positives = 425/425 (100%)
Query: 1 MATAEVLNIGKKLYEGKTKEVYELLDSPGKVLLQSKDQITAGNAARKNHLEGKAAISNKI 60
MATAEVLNIGKKLYEGKTKEVYELLDSPGKVLLQSKDQITAGNAARKNHLEGKAAISNKI
Sbjct: 1 MATAEVLNIGKKLYEGKTKEVYELLDSPGKVLLQSKDQITAGNAARKNHLEGKAAISNKI 60
Query: 61 TSCIFQLLQEAGIKTAFTRKCGETAFIAPQCEMIPIEWVCRRIATGSFLKRNPGVKEGYK 120
TSCIFQLLQEAGIKTAFTRKCGETAFIAPQCEMIPIEWVCRRIATGSFLKRNPGVKEGYK
Sbjct: 61 TSCIFQLLQEAGIKTAFTRKCGETAFIAPQCEMIPIEWVCRRIATGSFLKRNPGVKEGYK 120
Query: 121 FYPPKVELFFKDDANNDPQWSEEQLIAAKFCFAGLLIGQTEVDIMSHATQAIFEILEKSW 180
FYPPKVELFFKDDANNDPQWSEEQLIAAKFCFAGLLIGQTEVDIMSHATQAIFEILEKSW
Sbjct: 121 FYPPKVELFFKDDANNDPQWSEEQLIAAKFCFAGLLIGQTEVDIMSHATQAIFEILEKSW 180
Query: 181 LPQNCTLVDMKIEFGVDVTTKEIVLADVIDNDSWRLWPSGDRSQQKDKQSYRDLKEVTPE 240
LPQNCTLVDMKIEFGVDVTTKEIVLADVIDNDSWRLWPSGDRSQQKDKQSYRDLKEVTPE
Sbjct: 181 LPQNCTLVDMKIEFGVDVTTKEIVLADVIDNDSWRLWPSGDRSQQKDKQSYRDLKEVTPE 240
Query: 241 GLQMVKKNFEWVAERVELLLKSESQCRVVVLMGSTSDLGHCEKIKKACGNFGIPCELRVT 300
GLQMVKKNFEWVAERVELLLKSESQCRVVVLMGSTSDLGHCEKIKKACGNFGIPCELRVT
Sbjct: 241 GLQMVKKNFEWVAERVELLLKSESQCRVVVLMGSTSDLGHCEKIKKACGNFGIPCELRVT 300
Query: 301 SAHKGPDETLRIKAEYEGDGIPTVFVAVAGRSNGLGPVMSGNTAYPVISCPPLTPDWGVQ 360
SAHKGPDETLRIKAEYEGDGIPTVFVAVAGRSNGLGPVMSGNTAYPVISCPPLTPDWGVQ
Sbjct: 301 SAHKGPDETLRIKAEYEGDGIPTVFVAVAGRSNGLGPVMSGNTAYPVISCPPLTPDWGVQ 360
Query: 361 DVWSSLRLPSGLGCSTVLSPEGSAQFAAQIFGLSNHLVWSKLRASILNTWISLKQADKKI 420
DVWSSLRLPSGLGCSTVLSPEGSAQFAAQIFGLSNHLVWSKLRASILNTWISLKQADKKI
Sbjct: 361 DVWSSLRLPSGLGCSTVLSPEGSAQFAAQIFGLSNHLVWSKLRASILNTWISLKQADKKI 420
Query: 421 RECNL 425
RECNL
Sbjct: 421 RECNL 425
>gi|5453539 phosphoribosylaminoimidazole carboxylase,
phosphoribosylaminoimidazole succinocarboxamide
synthetase isoform 2 [Homo sapiens]
Length = 425
Score = 864 bits (2232), Expect = 0.0
Identities = 425/425 (100%), Positives = 425/425 (100%)
Query: 1 MATAEVLNIGKKLYEGKTKEVYELLDSPGKVLLQSKDQITAGNAARKNHLEGKAAISNKI 60
MATAEVLNIGKKLYEGKTKEVYELLDSPGKVLLQSKDQITAGNAARKNHLEGKAAISNKI
Sbjct: 1 MATAEVLNIGKKLYEGKTKEVYELLDSPGKVLLQSKDQITAGNAARKNHLEGKAAISNKI 60
Query: 61 TSCIFQLLQEAGIKTAFTRKCGETAFIAPQCEMIPIEWVCRRIATGSFLKRNPGVKEGYK 120
TSCIFQLLQEAGIKTAFTRKCGETAFIAPQCEMIPIEWVCRRIATGSFLKRNPGVKEGYK
Sbjct: 61 TSCIFQLLQEAGIKTAFTRKCGETAFIAPQCEMIPIEWVCRRIATGSFLKRNPGVKEGYK 120
Query: 121 FYPPKVELFFKDDANNDPQWSEEQLIAAKFCFAGLLIGQTEVDIMSHATQAIFEILEKSW 180
FYPPKVELFFKDDANNDPQWSEEQLIAAKFCFAGLLIGQTEVDIMSHATQAIFEILEKSW
Sbjct: 121 FYPPKVELFFKDDANNDPQWSEEQLIAAKFCFAGLLIGQTEVDIMSHATQAIFEILEKSW 180
Query: 181 LPQNCTLVDMKIEFGVDVTTKEIVLADVIDNDSWRLWPSGDRSQQKDKQSYRDLKEVTPE 240
LPQNCTLVDMKIEFGVDVTTKEIVLADVIDNDSWRLWPSGDRSQQKDKQSYRDLKEVTPE
Sbjct: 181 LPQNCTLVDMKIEFGVDVTTKEIVLADVIDNDSWRLWPSGDRSQQKDKQSYRDLKEVTPE 240
Query: 241 GLQMVKKNFEWVAERVELLLKSESQCRVVVLMGSTSDLGHCEKIKKACGNFGIPCELRVT 300
GLQMVKKNFEWVAERVELLLKSESQCRVVVLMGSTSDLGHCEKIKKACGNFGIPCELRVT
Sbjct: 241 GLQMVKKNFEWVAERVELLLKSESQCRVVVLMGSTSDLGHCEKIKKACGNFGIPCELRVT 300
Query: 301 SAHKGPDETLRIKAEYEGDGIPTVFVAVAGRSNGLGPVMSGNTAYPVISCPPLTPDWGVQ 360
SAHKGPDETLRIKAEYEGDGIPTVFVAVAGRSNGLGPVMSGNTAYPVISCPPLTPDWGVQ
Sbjct: 301 SAHKGPDETLRIKAEYEGDGIPTVFVAVAGRSNGLGPVMSGNTAYPVISCPPLTPDWGVQ 360
Query: 361 DVWSSLRLPSGLGCSTVLSPEGSAQFAAQIFGLSNHLVWSKLRASILNTWISLKQADKKI 420
DVWSSLRLPSGLGCSTVLSPEGSAQFAAQIFGLSNHLVWSKLRASILNTWISLKQADKKI
Sbjct: 361 DVWSSLRLPSGLGCSTVLSPEGSAQFAAQIFGLSNHLVWSKLRASILNTWISLKQADKKI 420
Query: 421 RECNL 425
RECNL
Sbjct: 421 RECNL 425
>gi|119220559 phosphoribosylaminoimidazole carboxylase,
phosphoribosylaminoimidazole succinocarboxamide
synthetase isoform 1 [Homo sapiens]
Length = 432
Score = 854 bits (2206), Expect = 0.0
Identities = 424/432 (98%), Positives = 424/432 (98%), Gaps = 7/432 (1%)
Query: 1 MATAEVLNIGKKLYEGKTKEVYELLDSPGKVLLQSKDQITAGNAARKNHLEGKAAISNKI 60
MATAEVLNIGKKLYEGKTKEVYELLDSPGKVLLQSKDQITAGNAARKNHLEGKAAISNKI
Sbjct: 1 MATAEVLNIGKKLYEGKTKEVYELLDSPGKVLLQSKDQITAGNAARKNHLEGKAAISNKI 60
Query: 61 TSCIFQLLQEA-------GIKTAFTRKCGETAFIAPQCEMIPIEWVCRRIATGSFLKRNP 113
TSCIFQLLQEA IKTAFTRKCGETAFIAPQCEMIPIEWVCRRIATGSFLKRNP
Sbjct: 61 TSCIFQLLQEAVTSYKSNRIKTAFTRKCGETAFIAPQCEMIPIEWVCRRIATGSFLKRNP 120
Query: 114 GVKEGYKFYPPKVELFFKDDANNDPQWSEEQLIAAKFCFAGLLIGQTEVDIMSHATQAIF 173
GVKEGYKFYPPKVELFFKDDANNDPQWSEEQLIAAKFCFAGLLIGQTEVDIMSHATQAIF
Sbjct: 121 GVKEGYKFYPPKVELFFKDDANNDPQWSEEQLIAAKFCFAGLLIGQTEVDIMSHATQAIF 180
Query: 174 EILEKSWLPQNCTLVDMKIEFGVDVTTKEIVLADVIDNDSWRLWPSGDRSQQKDKQSYRD 233
EILEKSWLPQNCTLVDMKIEFGVDVTTKEIVLADVIDNDSWRLWPSGDRSQQKDKQSYRD
Sbjct: 181 EILEKSWLPQNCTLVDMKIEFGVDVTTKEIVLADVIDNDSWRLWPSGDRSQQKDKQSYRD 240
Query: 234 LKEVTPEGLQMVKKNFEWVAERVELLLKSESQCRVVVLMGSTSDLGHCEKIKKACGNFGI 293
LKEVTPEGLQMVKKNFEWVAERVELLLKSESQCRVVVLMGSTSDLGHCEKIKKACGNFGI
Sbjct: 241 LKEVTPEGLQMVKKNFEWVAERVELLLKSESQCRVVVLMGSTSDLGHCEKIKKACGNFGI 300
Query: 294 PCELRVTSAHKGPDETLRIKAEYEGDGIPTVFVAVAGRSNGLGPVMSGNTAYPVISCPPL 353
PCELRVTSAHKGPDETLRIKAEYEGDGIPTVFVAVAGRSNGLGPVMSGNTAYPVISCPPL
Sbjct: 301 PCELRVTSAHKGPDETLRIKAEYEGDGIPTVFVAVAGRSNGLGPVMSGNTAYPVISCPPL 360
Query: 354 TPDWGVQDVWSSLRLPSGLGCSTVLSPEGSAQFAAQIFGLSNHLVWSKLRASILNTWISL 413
TPDWGVQDVWSSLRLPSGLGCSTVLSPEGSAQFAAQIFGLSNHLVWSKLRASILNTWISL
Sbjct: 361 TPDWGVQDVWSSLRLPSGLGCSTVLSPEGSAQFAAQIFGLSNHLVWSKLRASILNTWISL 420
Query: 414 KQADKKIRECNL 425
KQADKKIRECNL
Sbjct: 421 KQADKKIRECNL 432
>gi|148612801 KIAA1009 protein [Homo sapiens]
Length = 1403
Score = 32.0 bits (71), Expect = 1.1
Identities = 35/149 (23%), Positives = 63/149 (42%), Gaps = 17/149 (11%)
Query: 167 HATQAIFEILEKSWLPQNCTLVDMKIEFGVDVTTKEIVLADV--IDNDSWRLWPS----- 219
H ++ + +++E S +N D+ E + K+ +L D+ + D L
Sbjct: 764 HKSRFLSQVVEDSEPTRNQNFTDLLAELRMAQKEKDSLLEDIKRLKQDKQALEVDFEKMK 823
Query: 220 GDRSQQKDKQSY---------RDLKEVTPEGLQMVKKNFEWVAERVELLLKSESQCRVVV 270
+R Q KD+ +Y + L+E + + ++K +W AE ELL K + R
Sbjct: 824 KERDQAKDQIAYVTGEKLYEIKILEETHKQEISRLQKRLQWYAENQELLDKDALRLREAN 883
Query: 271 LMGSTSDLGHCEKIKKACGNFGIPCELRV 299
L EK+K GN I ++R+
Sbjct: 884 EEIEKLKL-EIEKLKAESGNPSIRQKIRL 911
>gi|118498347 DnaJ (Hsp40) homolog, subfamily C , member 25 [Homo
sapiens]
Length = 360
Score = 31.6 bits (70), Expect = 1.4
Identities = 14/34 (41%), Positives = 19/34 (55%)
Query: 107 SFLKRNPGVKEGYKFYPPKVELFFKDDANNDPQW 140
+FLKR +KE Y+ Y + E K NDP+W
Sbjct: 307 TFLKRELWIKENYEVYKQEQEEELKKKLANDPRW 340
>gi|28372497 ubiquitin protein ligase E3 component n-recognin 1
[Homo sapiens]
Length = 1749
Score = 31.2 bits (69), Expect = 1.9
Identities = 21/65 (32%), Positives = 32/65 (49%), Gaps = 10/65 (15%)
Query: 236 EVTPE-----GLQMVKKNF-----EWVAERVELLLKSESQCRVVVLMGSTSDLGHCEKIK 285
EV P+ +QM KN EW A ELLL + +C V+ STS + + +
Sbjct: 527 EVDPDWEAAIAIQMQLKNILLMFQEWCACDEELLLVAYKECHKAVMRCSTSFISSSKTVV 586
Query: 286 KACGN 290
++CG+
Sbjct: 587 QSCGH 591
>gi|61743980 stabilin 2 precursor [Homo sapiens]
Length = 2551
Score = 30.4 bits (67), Expect = 3.2
Identities = 14/40 (35%), Positives = 19/40 (47%)
Query: 281 CEKIKKACGNFGIPCELRVTSAHKGPDETLRIKAEYEGDG 320
C+K ACG + C + T + + KA YEGDG
Sbjct: 823 CDKQTSACGPYVQFCHIHATCEYSNGTASCICKAGYEGDG 862
>gi|42794760 acyl-CoA synthetase long-chain family member 5 isoform
b [Homo sapiens]
Length = 683
Score = 30.0 bits (66), Expect = 4.2
Identities = 34/146 (23%), Positives = 61/146 (41%), Gaps = 29/146 (19%)
Query: 117 EGYKFYPPKVELFFKDDANNDPQWSEEQLIAAKFCFAGLLIGQTEVDIMSHATQAIFEIL 176
+GYK P + F A N P+W +I+ C+ ++ D + +AI I+
Sbjct: 125 KGYKSSPDQFVGIF---AQNRPEW----IISELACYTYSMVAVPLYDTLG--PEAIVHIV 175
Query: 177 EKSWL-------PQNCTLVDMKIEFGVDVTTKEIVLADVIDNDSWRLWPSGDRS------ 223
K+ + PQ ++ +E G + K I+L D D+D L G++S
Sbjct: 176 NKADIAMVICDTPQKALVLIGNVEKGFTPSLKVIILMDPFDDD---LKQRGEKSGIEILS 232
Query: 224 ----QQKDKQSYRDLKEVTPEGLQMV 245
+ K+ +R +PE L ++
Sbjct: 233 LYDAENLGKEHFRKPVPPSPEDLSVI 258
>gi|42794758 acyl-CoA synthetase long-chain family member 5 isoform
b [Homo sapiens]
Length = 683
Score = 30.0 bits (66), Expect = 4.2
Identities = 34/146 (23%), Positives = 61/146 (41%), Gaps = 29/146 (19%)
Query: 117 EGYKFYPPKVELFFKDDANNDPQWSEEQLIAAKFCFAGLLIGQTEVDIMSHATQAIFEIL 176
+GYK P + F A N P+W +I+ C+ ++ D + +AI I+
Sbjct: 125 KGYKSSPDQFVGIF---AQNRPEW----IISELACYTYSMVAVPLYDTLG--PEAIVHIV 175
Query: 177 EKSWL-------PQNCTLVDMKIEFGVDVTTKEIVLADVIDNDSWRLWPSGDRS------ 223
K+ + PQ ++ +E G + K I+L D D+D L G++S
Sbjct: 176 NKADIAMVICDTPQKALVLIGNVEKGFTPSLKVIILMDPFDDD---LKQRGEKSGIEILS 232
Query: 224 ----QQKDKQSYRDLKEVTPEGLQMV 245
+ K+ +R +PE L ++
Sbjct: 233 LYDAENLGKEHFRKPVPPSPEDLSVI 258
>gi|42794756 acyl-CoA synthetase long-chain family member 5 isoform
a [Homo sapiens]
Length = 739
Score = 30.0 bits (66), Expect = 4.2
Identities = 34/146 (23%), Positives = 61/146 (41%), Gaps = 29/146 (19%)
Query: 117 EGYKFYPPKVELFFKDDANNDPQWSEEQLIAAKFCFAGLLIGQTEVDIMSHATQAIFEIL 176
+GYK P + F A N P+W +I+ C+ ++ D + +AI I+
Sbjct: 181 KGYKSSPDQFVGIF---AQNRPEW----IISELACYTYSMVAVPLYDTLG--PEAIVHIV 231
Query: 177 EKSWL-------PQNCTLVDMKIEFGVDVTTKEIVLADVIDNDSWRLWPSGDRS------ 223
K+ + PQ ++ +E G + K I+L D D+D L G++S
Sbjct: 232 NKADIAMVICDTPQKALVLIGNVEKGFTPSLKVIILMDPFDDD---LKQRGEKSGIEILS 288
Query: 224 ----QQKDKQSYRDLKEVTPEGLQMV 245
+ K+ +R +PE L ++
Sbjct: 289 LYDAENLGKEHFRKPVPPSPEDLSVI 314
>gi|40805854 isthmin 2 homolog isoform 3 [Homo sapiens]
Length = 292
Score = 29.3 bits (64), Expect = 7.1
Identities = 20/63 (31%), Positives = 28/63 (44%), Gaps = 2/63 (3%)
Query: 293 IPCELRVTSAHKGPDETLRIKAEYEGDGIPTVFVAVAGRSNGLGPV-MSGNTAYPV-ISC 350
+P + T + PD G+P V A S GLGPV M+ PV ++C
Sbjct: 193 LPELVHATLSTPNPDNQTMSLRRSGVPGLPAVGTAALASSRGLGPVAMAALPPRPVPVTC 252
Query: 351 PPL 353
PP+
Sbjct: 253 PPV 255
>gi|11055992 serine carboxypeptidase 1 precursor [Homo sapiens]
Length = 452
Score = 28.9 bits (63), Expect = 9.3
Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 9/90 (10%)
Query: 172 IFEILEKSWLPQNCTLVDMKIEFGVDVTT---KEIVLADVIDNDSW---RLWPSGDR-SQ 224
+F +E+ ++ ++VD +E G++VT + ++ D + ++W WP + SQ
Sbjct: 337 VFVNMEEDFMKPVISIVDELLEAGINVTVYNGQLDLIVDTMGQEAWVRKLKWPELPKFSQ 396
Query: 225 QKDKQSYRDLKEVTPEGLQMVKKN--FEWV 252
K K Y D K + KN F W+
Sbjct: 397 LKWKALYSDPKSLETSAFVKSYKNLAFYWI 426
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,436,247
Number of Sequences: 37866
Number of extensions: 716027
Number of successful extensions: 1490
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1482
Number of HSP's gapped (non-prelim): 13
length of query: 425
length of database: 18,247,518
effective HSP length: 105
effective length of query: 320
effective length of database: 14,271,588
effective search space: 4566908160
effective search space used: 4566908160
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.