Guide to the Human Genome
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Search of human proteins with 5453539

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5453539 phosphoribosylaminoimidazole carboxylase,
phosphoribosylaminoimidazole succinocarboxamide synthetase isoform 2
[Homo sapiens]
         (425 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|119220557 phosphoribosylaminoimidazole carboxylase, phosphori...   864   0.0  
gi|5453539 phosphoribosylaminoimidazole carboxylase, phosphoribo...   864   0.0  
gi|119220559 phosphoribosylaminoimidazole carboxylase, phosphori...   854   0.0  
gi|148612801 KIAA1009 protein [Homo sapiens]                           32   1.1  
gi|118498347 DnaJ (Hsp40) homolog, subfamily C , member 25 [Homo...    32   1.4  
gi|28372497 ubiquitin protein ligase E3 component n-recognin 1 [...    31   1.9  
gi|61743980 stabilin 2 precursor [Homo sapiens]                        30   3.2  
gi|42794760 acyl-CoA synthetase long-chain family member 5 isofo...    30   4.2  
gi|42794758 acyl-CoA synthetase long-chain family member 5 isofo...    30   4.2  
gi|42794756 acyl-CoA synthetase long-chain family member 5 isofo...    30   4.2  
gi|40805854 isthmin 2 homolog isoform 3 [Homo sapiens]                 29   7.1  
gi|11055992 serine carboxypeptidase 1 precursor [Homo sapiens]         29   9.3  

>gi|119220557 phosphoribosylaminoimidazole carboxylase,
           phosphoribosylaminoimidazole succinocarboxamide
           synthetase isoform 2 [Homo sapiens]
          Length = 425

 Score =  864 bits (2232), Expect = 0.0
 Identities = 425/425 (100%), Positives = 425/425 (100%)

Query: 1   MATAEVLNIGKKLYEGKTKEVYELLDSPGKVLLQSKDQITAGNAARKNHLEGKAAISNKI 60
           MATAEVLNIGKKLYEGKTKEVYELLDSPGKVLLQSKDQITAGNAARKNHLEGKAAISNKI
Sbjct: 1   MATAEVLNIGKKLYEGKTKEVYELLDSPGKVLLQSKDQITAGNAARKNHLEGKAAISNKI 60

Query: 61  TSCIFQLLQEAGIKTAFTRKCGETAFIAPQCEMIPIEWVCRRIATGSFLKRNPGVKEGYK 120
           TSCIFQLLQEAGIKTAFTRKCGETAFIAPQCEMIPIEWVCRRIATGSFLKRNPGVKEGYK
Sbjct: 61  TSCIFQLLQEAGIKTAFTRKCGETAFIAPQCEMIPIEWVCRRIATGSFLKRNPGVKEGYK 120

Query: 121 FYPPKVELFFKDDANNDPQWSEEQLIAAKFCFAGLLIGQTEVDIMSHATQAIFEILEKSW 180
           FYPPKVELFFKDDANNDPQWSEEQLIAAKFCFAGLLIGQTEVDIMSHATQAIFEILEKSW
Sbjct: 121 FYPPKVELFFKDDANNDPQWSEEQLIAAKFCFAGLLIGQTEVDIMSHATQAIFEILEKSW 180

Query: 181 LPQNCTLVDMKIEFGVDVTTKEIVLADVIDNDSWRLWPSGDRSQQKDKQSYRDLKEVTPE 240
           LPQNCTLVDMKIEFGVDVTTKEIVLADVIDNDSWRLWPSGDRSQQKDKQSYRDLKEVTPE
Sbjct: 181 LPQNCTLVDMKIEFGVDVTTKEIVLADVIDNDSWRLWPSGDRSQQKDKQSYRDLKEVTPE 240

Query: 241 GLQMVKKNFEWVAERVELLLKSESQCRVVVLMGSTSDLGHCEKIKKACGNFGIPCELRVT 300
           GLQMVKKNFEWVAERVELLLKSESQCRVVVLMGSTSDLGHCEKIKKACGNFGIPCELRVT
Sbjct: 241 GLQMVKKNFEWVAERVELLLKSESQCRVVVLMGSTSDLGHCEKIKKACGNFGIPCELRVT 300

Query: 301 SAHKGPDETLRIKAEYEGDGIPTVFVAVAGRSNGLGPVMSGNTAYPVISCPPLTPDWGVQ 360
           SAHKGPDETLRIKAEYEGDGIPTVFVAVAGRSNGLGPVMSGNTAYPVISCPPLTPDWGVQ
Sbjct: 301 SAHKGPDETLRIKAEYEGDGIPTVFVAVAGRSNGLGPVMSGNTAYPVISCPPLTPDWGVQ 360

Query: 361 DVWSSLRLPSGLGCSTVLSPEGSAQFAAQIFGLSNHLVWSKLRASILNTWISLKQADKKI 420
           DVWSSLRLPSGLGCSTVLSPEGSAQFAAQIFGLSNHLVWSKLRASILNTWISLKQADKKI
Sbjct: 361 DVWSSLRLPSGLGCSTVLSPEGSAQFAAQIFGLSNHLVWSKLRASILNTWISLKQADKKI 420

Query: 421 RECNL 425
           RECNL
Sbjct: 421 RECNL 425


>gi|5453539 phosphoribosylaminoimidazole carboxylase,
           phosphoribosylaminoimidazole succinocarboxamide
           synthetase isoform 2 [Homo sapiens]
          Length = 425

 Score =  864 bits (2232), Expect = 0.0
 Identities = 425/425 (100%), Positives = 425/425 (100%)

Query: 1   MATAEVLNIGKKLYEGKTKEVYELLDSPGKVLLQSKDQITAGNAARKNHLEGKAAISNKI 60
           MATAEVLNIGKKLYEGKTKEVYELLDSPGKVLLQSKDQITAGNAARKNHLEGKAAISNKI
Sbjct: 1   MATAEVLNIGKKLYEGKTKEVYELLDSPGKVLLQSKDQITAGNAARKNHLEGKAAISNKI 60

Query: 61  TSCIFQLLQEAGIKTAFTRKCGETAFIAPQCEMIPIEWVCRRIATGSFLKRNPGVKEGYK 120
           TSCIFQLLQEAGIKTAFTRKCGETAFIAPQCEMIPIEWVCRRIATGSFLKRNPGVKEGYK
Sbjct: 61  TSCIFQLLQEAGIKTAFTRKCGETAFIAPQCEMIPIEWVCRRIATGSFLKRNPGVKEGYK 120

Query: 121 FYPPKVELFFKDDANNDPQWSEEQLIAAKFCFAGLLIGQTEVDIMSHATQAIFEILEKSW 180
           FYPPKVELFFKDDANNDPQWSEEQLIAAKFCFAGLLIGQTEVDIMSHATQAIFEILEKSW
Sbjct: 121 FYPPKVELFFKDDANNDPQWSEEQLIAAKFCFAGLLIGQTEVDIMSHATQAIFEILEKSW 180

Query: 181 LPQNCTLVDMKIEFGVDVTTKEIVLADVIDNDSWRLWPSGDRSQQKDKQSYRDLKEVTPE 240
           LPQNCTLVDMKIEFGVDVTTKEIVLADVIDNDSWRLWPSGDRSQQKDKQSYRDLKEVTPE
Sbjct: 181 LPQNCTLVDMKIEFGVDVTTKEIVLADVIDNDSWRLWPSGDRSQQKDKQSYRDLKEVTPE 240

Query: 241 GLQMVKKNFEWVAERVELLLKSESQCRVVVLMGSTSDLGHCEKIKKACGNFGIPCELRVT 300
           GLQMVKKNFEWVAERVELLLKSESQCRVVVLMGSTSDLGHCEKIKKACGNFGIPCELRVT
Sbjct: 241 GLQMVKKNFEWVAERVELLLKSESQCRVVVLMGSTSDLGHCEKIKKACGNFGIPCELRVT 300

Query: 301 SAHKGPDETLRIKAEYEGDGIPTVFVAVAGRSNGLGPVMSGNTAYPVISCPPLTPDWGVQ 360
           SAHKGPDETLRIKAEYEGDGIPTVFVAVAGRSNGLGPVMSGNTAYPVISCPPLTPDWGVQ
Sbjct: 301 SAHKGPDETLRIKAEYEGDGIPTVFVAVAGRSNGLGPVMSGNTAYPVISCPPLTPDWGVQ 360

Query: 361 DVWSSLRLPSGLGCSTVLSPEGSAQFAAQIFGLSNHLVWSKLRASILNTWISLKQADKKI 420
           DVWSSLRLPSGLGCSTVLSPEGSAQFAAQIFGLSNHLVWSKLRASILNTWISLKQADKKI
Sbjct: 361 DVWSSLRLPSGLGCSTVLSPEGSAQFAAQIFGLSNHLVWSKLRASILNTWISLKQADKKI 420

Query: 421 RECNL 425
           RECNL
Sbjct: 421 RECNL 425


>gi|119220559 phosphoribosylaminoimidazole carboxylase,
           phosphoribosylaminoimidazole succinocarboxamide
           synthetase isoform 1 [Homo sapiens]
          Length = 432

 Score =  854 bits (2206), Expect = 0.0
 Identities = 424/432 (98%), Positives = 424/432 (98%), Gaps = 7/432 (1%)

Query: 1   MATAEVLNIGKKLYEGKTKEVYELLDSPGKVLLQSKDQITAGNAARKNHLEGKAAISNKI 60
           MATAEVLNIGKKLYEGKTKEVYELLDSPGKVLLQSKDQITAGNAARKNHLEGKAAISNKI
Sbjct: 1   MATAEVLNIGKKLYEGKTKEVYELLDSPGKVLLQSKDQITAGNAARKNHLEGKAAISNKI 60

Query: 61  TSCIFQLLQEA-------GIKTAFTRKCGETAFIAPQCEMIPIEWVCRRIATGSFLKRNP 113
           TSCIFQLLQEA        IKTAFTRKCGETAFIAPQCEMIPIEWVCRRIATGSFLKRNP
Sbjct: 61  TSCIFQLLQEAVTSYKSNRIKTAFTRKCGETAFIAPQCEMIPIEWVCRRIATGSFLKRNP 120

Query: 114 GVKEGYKFYPPKVELFFKDDANNDPQWSEEQLIAAKFCFAGLLIGQTEVDIMSHATQAIF 173
           GVKEGYKFYPPKVELFFKDDANNDPQWSEEQLIAAKFCFAGLLIGQTEVDIMSHATQAIF
Sbjct: 121 GVKEGYKFYPPKVELFFKDDANNDPQWSEEQLIAAKFCFAGLLIGQTEVDIMSHATQAIF 180

Query: 174 EILEKSWLPQNCTLVDMKIEFGVDVTTKEIVLADVIDNDSWRLWPSGDRSQQKDKQSYRD 233
           EILEKSWLPQNCTLVDMKIEFGVDVTTKEIVLADVIDNDSWRLWPSGDRSQQKDKQSYRD
Sbjct: 181 EILEKSWLPQNCTLVDMKIEFGVDVTTKEIVLADVIDNDSWRLWPSGDRSQQKDKQSYRD 240

Query: 234 LKEVTPEGLQMVKKNFEWVAERVELLLKSESQCRVVVLMGSTSDLGHCEKIKKACGNFGI 293
           LKEVTPEGLQMVKKNFEWVAERVELLLKSESQCRVVVLMGSTSDLGHCEKIKKACGNFGI
Sbjct: 241 LKEVTPEGLQMVKKNFEWVAERVELLLKSESQCRVVVLMGSTSDLGHCEKIKKACGNFGI 300

Query: 294 PCELRVTSAHKGPDETLRIKAEYEGDGIPTVFVAVAGRSNGLGPVMSGNTAYPVISCPPL 353
           PCELRVTSAHKGPDETLRIKAEYEGDGIPTVFVAVAGRSNGLGPVMSGNTAYPVISCPPL
Sbjct: 301 PCELRVTSAHKGPDETLRIKAEYEGDGIPTVFVAVAGRSNGLGPVMSGNTAYPVISCPPL 360

Query: 354 TPDWGVQDVWSSLRLPSGLGCSTVLSPEGSAQFAAQIFGLSNHLVWSKLRASILNTWISL 413
           TPDWGVQDVWSSLRLPSGLGCSTVLSPEGSAQFAAQIFGLSNHLVWSKLRASILNTWISL
Sbjct: 361 TPDWGVQDVWSSLRLPSGLGCSTVLSPEGSAQFAAQIFGLSNHLVWSKLRASILNTWISL 420

Query: 414 KQADKKIRECNL 425
           KQADKKIRECNL
Sbjct: 421 KQADKKIRECNL 432


>gi|148612801 KIAA1009 protein [Homo sapiens]
          Length = 1403

 Score = 32.0 bits (71), Expect = 1.1
 Identities = 35/149 (23%), Positives = 63/149 (42%), Gaps = 17/149 (11%)

Query: 167 HATQAIFEILEKSWLPQNCTLVDMKIEFGVDVTTKEIVLADV--IDNDSWRLWPS----- 219
           H ++ + +++E S   +N    D+  E  +    K+ +L D+  +  D   L        
Sbjct: 764 HKSRFLSQVVEDSEPTRNQNFTDLLAELRMAQKEKDSLLEDIKRLKQDKQALEVDFEKMK 823

Query: 220 GDRSQQKDKQSY---------RDLKEVTPEGLQMVKKNFEWVAERVELLLKSESQCRVVV 270
            +R Q KD+ +Y         + L+E   + +  ++K  +W AE  ELL K   + R   
Sbjct: 824 KERDQAKDQIAYVTGEKLYEIKILEETHKQEISRLQKRLQWYAENQELLDKDALRLREAN 883

Query: 271 LMGSTSDLGHCEKIKKACGNFGIPCELRV 299
                  L   EK+K   GN  I  ++R+
Sbjct: 884 EEIEKLKL-EIEKLKAESGNPSIRQKIRL 911


>gi|118498347 DnaJ (Hsp40) homolog, subfamily C , member 25 [Homo
           sapiens]
          Length = 360

 Score = 31.6 bits (70), Expect = 1.4
 Identities = 14/34 (41%), Positives = 19/34 (55%)

Query: 107 SFLKRNPGVKEGYKFYPPKVELFFKDDANNDPQW 140
           +FLKR   +KE Y+ Y  + E   K    NDP+W
Sbjct: 307 TFLKRELWIKENYEVYKQEQEEELKKKLANDPRW 340


>gi|28372497 ubiquitin protein ligase E3 component n-recognin 1
           [Homo sapiens]
          Length = 1749

 Score = 31.2 bits (69), Expect = 1.9
 Identities = 21/65 (32%), Positives = 32/65 (49%), Gaps = 10/65 (15%)

Query: 236 EVTPE-----GLQMVKKNF-----EWVAERVELLLKSESQCRVVVLMGSTSDLGHCEKIK 285
           EV P+      +QM  KN      EW A   ELLL +  +C   V+  STS +   + + 
Sbjct: 527 EVDPDWEAAIAIQMQLKNILLMFQEWCACDEELLLVAYKECHKAVMRCSTSFISSSKTVV 586

Query: 286 KACGN 290
           ++CG+
Sbjct: 587 QSCGH 591


>gi|61743980 stabilin 2 precursor [Homo sapiens]
          Length = 2551

 Score = 30.4 bits (67), Expect = 3.2
 Identities = 14/40 (35%), Positives = 19/40 (47%)

Query: 281 CEKIKKACGNFGIPCELRVTSAHKGPDETLRIKAEYEGDG 320
           C+K   ACG +   C +  T  +     +   KA YEGDG
Sbjct: 823 CDKQTSACGPYVQFCHIHATCEYSNGTASCICKAGYEGDG 862


>gi|42794760 acyl-CoA synthetase long-chain family member 5 isoform
           b [Homo sapiens]
          Length = 683

 Score = 30.0 bits (66), Expect = 4.2
 Identities = 34/146 (23%), Positives = 61/146 (41%), Gaps = 29/146 (19%)

Query: 117 EGYKFYPPKVELFFKDDANNDPQWSEEQLIAAKFCFAGLLIGQTEVDIMSHATQAIFEIL 176
           +GYK  P +    F   A N P+W    +I+   C+   ++     D +    +AI  I+
Sbjct: 125 KGYKSSPDQFVGIF---AQNRPEW----IISELACYTYSMVAVPLYDTLG--PEAIVHIV 175

Query: 177 EKSWL-------PQNCTLVDMKIEFGVDVTTKEIVLADVIDNDSWRLWPSGDRS------ 223
            K+ +       PQ   ++   +E G   + K I+L D  D+D   L   G++S      
Sbjct: 176 NKADIAMVICDTPQKALVLIGNVEKGFTPSLKVIILMDPFDDD---LKQRGEKSGIEILS 232

Query: 224 ----QQKDKQSYRDLKEVTPEGLQMV 245
               +   K+ +R     +PE L ++
Sbjct: 233 LYDAENLGKEHFRKPVPPSPEDLSVI 258


>gi|42794758 acyl-CoA synthetase long-chain family member 5 isoform
           b [Homo sapiens]
          Length = 683

 Score = 30.0 bits (66), Expect = 4.2
 Identities = 34/146 (23%), Positives = 61/146 (41%), Gaps = 29/146 (19%)

Query: 117 EGYKFYPPKVELFFKDDANNDPQWSEEQLIAAKFCFAGLLIGQTEVDIMSHATQAIFEIL 176
           +GYK  P +    F   A N P+W    +I+   C+   ++     D +    +AI  I+
Sbjct: 125 KGYKSSPDQFVGIF---AQNRPEW----IISELACYTYSMVAVPLYDTLG--PEAIVHIV 175

Query: 177 EKSWL-------PQNCTLVDMKIEFGVDVTTKEIVLADVIDNDSWRLWPSGDRS------ 223
            K+ +       PQ   ++   +E G   + K I+L D  D+D   L   G++S      
Sbjct: 176 NKADIAMVICDTPQKALVLIGNVEKGFTPSLKVIILMDPFDDD---LKQRGEKSGIEILS 232

Query: 224 ----QQKDKQSYRDLKEVTPEGLQMV 245
               +   K+ +R     +PE L ++
Sbjct: 233 LYDAENLGKEHFRKPVPPSPEDLSVI 258


>gi|42794756 acyl-CoA synthetase long-chain family member 5 isoform
           a [Homo sapiens]
          Length = 739

 Score = 30.0 bits (66), Expect = 4.2
 Identities = 34/146 (23%), Positives = 61/146 (41%), Gaps = 29/146 (19%)

Query: 117 EGYKFYPPKVELFFKDDANNDPQWSEEQLIAAKFCFAGLLIGQTEVDIMSHATQAIFEIL 176
           +GYK  P +    F   A N P+W    +I+   C+   ++     D +    +AI  I+
Sbjct: 181 KGYKSSPDQFVGIF---AQNRPEW----IISELACYTYSMVAVPLYDTLG--PEAIVHIV 231

Query: 177 EKSWL-------PQNCTLVDMKIEFGVDVTTKEIVLADVIDNDSWRLWPSGDRS------ 223
            K+ +       PQ   ++   +E G   + K I+L D  D+D   L   G++S      
Sbjct: 232 NKADIAMVICDTPQKALVLIGNVEKGFTPSLKVIILMDPFDDD---LKQRGEKSGIEILS 288

Query: 224 ----QQKDKQSYRDLKEVTPEGLQMV 245
               +   K+ +R     +PE L ++
Sbjct: 289 LYDAENLGKEHFRKPVPPSPEDLSVI 314


>gi|40805854 isthmin 2 homolog isoform 3 [Homo sapiens]
          Length = 292

 Score = 29.3 bits (64), Expect = 7.1
 Identities = 20/63 (31%), Positives = 28/63 (44%), Gaps = 2/63 (3%)

Query: 293 IPCELRVTSAHKGPDETLRIKAEYEGDGIPTVFVAVAGRSNGLGPV-MSGNTAYPV-ISC 350
           +P  +  T +   PD            G+P V  A    S GLGPV M+     PV ++C
Sbjct: 193 LPELVHATLSTPNPDNQTMSLRRSGVPGLPAVGTAALASSRGLGPVAMAALPPRPVPVTC 252

Query: 351 PPL 353
           PP+
Sbjct: 253 PPV 255


>gi|11055992 serine carboxypeptidase 1 precursor [Homo sapiens]
          Length = 452

 Score = 28.9 bits (63), Expect = 9.3
 Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 9/90 (10%)

Query: 172 IFEILEKSWLPQNCTLVDMKIEFGVDVTT---KEIVLADVIDNDSW---RLWPSGDR-SQ 224
           +F  +E+ ++    ++VD  +E G++VT    +  ++ D +  ++W     WP   + SQ
Sbjct: 337 VFVNMEEDFMKPVISIVDELLEAGINVTVYNGQLDLIVDTMGQEAWVRKLKWPELPKFSQ 396

Query: 225 QKDKQSYRDLKEVTPEGLQMVKKN--FEWV 252
            K K  Y D K +         KN  F W+
Sbjct: 397 LKWKALYSDPKSLETSAFVKSYKNLAFYWI 426


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,436,247
Number of Sequences: 37866
Number of extensions: 716027
Number of successful extensions: 1490
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1482
Number of HSP's gapped (non-prelim): 13
length of query: 425
length of database: 18,247,518
effective HSP length: 105
effective length of query: 320
effective length of database: 14,271,588
effective search space: 4566908160
effective search space used: 4566908160
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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