Guide to the Human Genome
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Search of human proteins with 51972218

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|51972218 von Hippel-Lindau tumor suppressor-like [Homo
sapiens]
         (139 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|51972218 von Hippel-Lindau tumor suppressor-like [Homo sapiens]    293   4e-80
gi|4507891 von Hippel-Lindau tumor suppressor isoform 1 [Homo sa...   170   3e-43
gi|38045906 von Hippel-Lindau tumor suppressor isoform 2 [Homo s...   103   3e-23
gi|225543438 complement component 2 isoform 2 preproprotein [Hom...    27   5.4  
gi|14550407 complement component 2 isoform 1 preproprotein [Homo...    27   5.4  
gi|40538728 pleckstrin homology domain containing, family M (wit...    27   7.0  
gi|24308251 bile acid beta-glucosidase [Homo sapiens]                  27   7.0  

>gi|51972218 von Hippel-Lindau tumor suppressor-like [Homo sapiens]
          Length = 139

 Score =  293 bits (749), Expect = 4e-80
 Identities = 139/139 (100%), Positives = 139/139 (100%)

Query: 1   MPWRAGNGVGLEAQAGTQEAGPEEYCQEELGAEEEMAARAAWPVLRSVNSRELSRIIICN 60
           MPWRAGNGVGLEAQAGTQEAGPEEYCQEELGAEEEMAARAAWPVLRSVNSRELSRIIICN
Sbjct: 1   MPWRAGNGVGLEAQAGTQEAGPEEYCQEELGAEEEMAARAAWPVLRSVNSRELSRIIICN 60

Query: 61  HSPRIVLPVWLNYYGKLLPYLTLLPGRDFRIHNFRSHPWLFRDARTHDKLLVNQTELFVP 120
           HSPRIVLPVWLNYYGKLLPYLTLLPGRDFRIHNFRSHPWLFRDARTHDKLLVNQTELFVP
Sbjct: 61  HSPRIVLPVWLNYYGKLLPYLTLLPGRDFRIHNFRSHPWLFRDARTHDKLLVNQTELFVP 120

Query: 121 SSNVNGQPVFANITLQCIP 139
           SSNVNGQPVFANITLQCIP
Sbjct: 121 SSNVNGQPVFANITLQCIP 139


>gi|4507891 von Hippel-Lindau tumor suppressor isoform 1 [Homo
           sapiens]
          Length = 213

 Score =  170 bits (431), Expect = 3e-43
 Identities = 84/122 (68%), Positives = 97/122 (79%)

Query: 14  QAGTQEAGPEEYCQEELGAEEEMAARAAWPVLRSVNSRELSRIIICNHSPRIVLPVWLNY 73
           ++G +E+GPEE   EELGAEEEM A    PVLRSVNSRE S++I CN SPR+VLPVWLN+
Sbjct: 32  ESGAEESGPEESGPEELGAEEEMEAGRPRPVLRSVNSREPSQVIFCNRSPRVVLPVWLNF 91

Query: 74  YGKLLPYLTLLPGRDFRIHNFRSHPWLFRDARTHDKLLVNQTELFVPSSNVNGQPVFANI 133
            G+  PY TL PG   RIH++R H WLFRDA THD LLVNQTELFVPS NV+GQP+FANI
Sbjct: 92  DGEPQPYPTLPPGTGRRIHSYRGHLWLFRDAGTHDGLLVNQTELFVPSLNVDGQPIFANI 151

Query: 134 TL 135
           TL
Sbjct: 152 TL 153


>gi|38045906 von Hippel-Lindau tumor suppressor isoform 2 [Homo
           sapiens]
          Length = 172

 Score =  103 bits (258), Expect = 3e-23
 Identities = 51/82 (62%), Positives = 62/82 (75%)

Query: 14  QAGTQEAGPEEYCQEELGAEEEMAARAAWPVLRSVNSRELSRIIICNHSPRIVLPVWLNY 73
           ++G +E+GPEE   EELGAEEEM A    PVLRSVNSRE S++I CN SPR+VLPVWLN+
Sbjct: 32  ESGAEESGPEESGPEELGAEEEMEAGRPRPVLRSVNSREPSQVIFCNRSPRVVLPVWLNF 91

Query: 74  YGKLLPYLTLLPGRDFRIHNFR 95
            G+  PY TL PG   RIH++R
Sbjct: 92  DGEPQPYPTLPPGTGRRIHSYR 113


>gi|225543438 complement component 2 isoform 2 preproprotein [Homo
           sapiens]
          Length = 620

 Score = 26.9 bits (58), Expect = 5.4
 Identities = 12/25 (48%), Positives = 14/25 (56%)

Query: 76  KLLPYLTLLPGRDFRIHNFRSHPWL 100
           K  P   + P RDF I+ FR  PWL
Sbjct: 583 KRAPRSKVPPPRDFHINLFRMQPWL 607


>gi|14550407 complement component 2 isoform 1 preproprotein [Homo
           sapiens]
          Length = 752

 Score = 26.9 bits (58), Expect = 5.4
 Identities = 12/25 (48%), Positives = 14/25 (56%)

Query: 76  KLLPYLTLLPGRDFRIHNFRSHPWL 100
           K  P   + P RDF I+ FR  PWL
Sbjct: 715 KRAPRSKVPPPRDFHINLFRMQPWL 739


>gi|40538728 pleckstrin homology domain containing, family M (with
           RUN domain) member 1 [Homo sapiens]
          Length = 1056

 Score = 26.6 bits (57), Expect = 7.0
 Identities = 30/109 (27%), Positives = 48/109 (44%), Gaps = 11/109 (10%)

Query: 10  GLEAQAGTQEAGPEEYCQEELGAEEEMAARAAWPVLRSVNSR----ELSRIIICNHSP-- 63
           GL A+    EAG +   +++   ++ +     WP+L++V  +    EL  +   N     
Sbjct: 61  GLHAKHIRAEAGGK---RKKSAHQKPLPQPVFWPLLKAVTHKHIISELEHLTFVNTDVGR 117

Query: 64  -RIVLPVWLNYYGKLLPYLTLLPGRDFRIHNFRSHPWLFRDARTHDKLL 111
            R  L + LN  G +  YL LL     R+H +     L RDA   + LL
Sbjct: 118 CRAWLRLALND-GLMECYLKLLLQEQARLHEYYQPTALLRDAEEGEFLL 165


>gi|24308251 bile acid beta-glucosidase [Homo sapiens]
          Length = 927

 Score = 26.6 bits (57), Expect = 7.0
 Identities = 11/35 (31%), Positives = 16/35 (45%)

Query: 2  PWRAGNGVGLEAQAGTQEAGPEEYCQEELGAEEEM 36
          P   G GV    Q    +  P+ YC EE G  +++
Sbjct: 6  PGNMGTGVPASEQISCAKEDPQVYCPEETGGTKDV 40


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.138    0.443 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,589,780
Number of Sequences: 37866
Number of extensions: 224789
Number of successful extensions: 562
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 550
Number of HSP's gapped (non-prelim): 9
length of query: 139
length of database: 18,247,518
effective HSP length: 92
effective length of query: 47
effective length of database: 14,763,846
effective search space: 693900762
effective search space used: 693900762
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 56 (26.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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