Search of human proteins with 51873036

Search of human proteins with 51873036

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|51873036 oxoglutarate (alpha-ketoglutarate) dehydrogenase
(lipoamide) isoform 1 precursor [Homo sapiens]
         (1023 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|51873036 oxoglutarate (alpha-ketoglutarate) dehydrogenase (li...  2097   0.0  
gi|221316661 oxoglutarate dehydrogenase-like isoform a [Homo sap...  1612   0.0  
gi|221316665 oxoglutarate dehydrogenase-like isoform b [Homo sap...  1528   0.0  
gi|221316669 oxoglutarate dehydrogenase-like isoform c [Homo sap...  1396   0.0  
gi|51873038 oxoglutarate (alpha-ketoglutarate) dehydrogenase (li...   811   0.0  
gi|38788380 dehydrogenase E1 and transketolase domain containing...   574   e-163
gi|4557353 branched chain keto acid dehydrogenase E1 beta precur...    37   0.095
gi|34101272 branched chain keto acid dehydrogenase E1 beta precu...    37   0.095
gi|4505685 pyruvate dehydrogenase E1 alpha 1 precursor [Homo sap...    37   0.12 
gi|4885543 pyruvate dehydrogenase E1 alpha 2 [Homo sapiens]            36   0.16 
gi|224586880 Ras protein-specific guanine nucleotide-releasing f...    35   0.36 
gi|24797099 Ras protein-specific guanine nucleotide-releasing fa...    35   0.36 
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]    34   0.62 
gi|126090663 zinc finger homeodomain 4 [Homo sapiens]                  30   8.9  
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ...    30   8.9  

>gi|51873036 oxoglutarate (alpha-ketoglutarate) dehydrogenase
            (lipoamide) isoform 1 precursor [Homo sapiens]
          Length = 1023

 Score = 2097 bits (5434), Expect = 0.0
 Identities = 1023/1023 (100%), Positives = 1023/1023 (100%)

Query: 1    MFHLRTCAAKLRPLTASQTVKTFSQNRPAAARTFQQIRCYSAPVAAEPFLSGTSSNYVEE 60
            MFHLRTCAAKLRPLTASQTVKTFSQNRPAAARTFQQIRCYSAPVAAEPFLSGTSSNYVEE
Sbjct: 1    MFHLRTCAAKLRPLTASQTVKTFSQNRPAAARTFQQIRCYSAPVAAEPFLSGTSSNYVEE 60

Query: 61   MYCAWLENPKSVHKSWDIFFRNTNAGAPPGTAYQSPLPLSRGSLAAVAHAQSLVEAQPNV 120
            MYCAWLENPKSVHKSWDIFFRNTNAGAPPGTAYQSPLPLSRGSLAAVAHAQSLVEAQPNV
Sbjct: 61   MYCAWLENPKSVHKSWDIFFRNTNAGAPPGTAYQSPLPLSRGSLAAVAHAQSLVEAQPNV 120

Query: 121  DKLVEDHLAVQSLIRAYQIRGHHVAQLDPLGILDADLDSSVPADIISSTDKLGFYGLDES 180
            DKLVEDHLAVQSLIRAYQIRGHHVAQLDPLGILDADLDSSVPADIISSTDKLGFYGLDES
Sbjct: 121  DKLVEDHLAVQSLIRAYQIRGHHVAQLDPLGILDADLDSSVPADIISSTDKLGFYGLDES 180

Query: 181  DLDKVFHLPTTTFIGGQESALPLREIIRRLEMAYCQHIGVEFMFINDLEQCQWIRQKFET 240
            DLDKVFHLPTTTFIGGQESALPLREIIRRLEMAYCQHIGVEFMFINDLEQCQWIRQKFET
Sbjct: 181  DLDKVFHLPTTTFIGGQESALPLREIIRRLEMAYCQHIGVEFMFINDLEQCQWIRQKFET 240

Query: 241  PGIMQFTNEEKRTLLARLVRSTRFEEFLQRKWSSEKRFGLEGCEVLIPALKTIIDKSSEN 300
            PGIMQFTNEEKRTLLARLVRSTRFEEFLQRKWSSEKRFGLEGCEVLIPALKTIIDKSSEN
Sbjct: 241  PGIMQFTNEEKRTLLARLVRSTRFEEFLQRKWSSEKRFGLEGCEVLIPALKTIIDKSSEN 300

Query: 301  GVDYVIMGMPHRGRLNVLANVIRKELEQIFCQFDSKLEAADEGSGDVKYHLGMYHRRINR 360
            GVDYVIMGMPHRGRLNVLANVIRKELEQIFCQFDSKLEAADEGSGDVKYHLGMYHRRINR
Sbjct: 301  GVDYVIMGMPHRGRLNVLANVIRKELEQIFCQFDSKLEAADEGSGDVKYHLGMYHRRINR 360

Query: 361  VTDRNITLSLVANPSHLEAADPVVMGKTKAEQFYCGDTEGKKVMSILLHGDAAFAGQGIV 420
            VTDRNITLSLVANPSHLEAADPVVMGKTKAEQFYCGDTEGKKVMSILLHGDAAFAGQGIV
Sbjct: 361  VTDRNITLSLVANPSHLEAADPVVMGKTKAEQFYCGDTEGKKVMSILLHGDAAFAGQGIV 420

Query: 421  YETFHLSDLPSYTTHGTVHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNSDDP 480
            YETFHLSDLPSYTTHGTVHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNSDDP
Sbjct: 421  YETFHLSDLPSYTTHGTVHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNSDDP 480

Query: 481  EAVMYVCKVAAEWRSTFHKDVVVDLVCYRRNGHNEMDEPMFTQPLMYKQIRKQKPVLQKY 540
            EAVMYVCKVAAEWRSTFHKDVVVDLVCYRRNGHNEMDEPMFTQPLMYKQIRKQKPVLQKY
Sbjct: 481  EAVMYVCKVAAEWRSTFHKDVVVDLVCYRRNGHNEMDEPMFTQPLMYKQIRKQKPVLQKY 540

Query: 541  AELLVSQGVVNQPEYEEEISKYDKICEEAFARSKDEKILHIKHWLDSPWPGFFTLDGQPR 600
            AELLVSQGVVNQPEYEEEISKYDKICEEAFARSKDEKILHIKHWLDSPWPGFFTLDGQPR
Sbjct: 541  AELLVSQGVVNQPEYEEEISKYDKICEEAFARSKDEKILHIKHWLDSPWPGFFTLDGQPR 600

Query: 601  SMSCPSTGLTEDILTHIGNVASSVPVENFTIHGGLSRILKTRGEMVKNRTVDWALAEYMA 660
            SMSCPSTGLTEDILTHIGNVASSVPVENFTIHGGLSRILKTRGEMVKNRTVDWALAEYMA
Sbjct: 601  SMSCPSTGLTEDILTHIGNVASSVPVENFTIHGGLSRILKTRGEMVKNRTVDWALAEYMA 660

Query: 661  FGSLLKEGIHIRLSGQDVERGTFSHRHHVLHDQNVDKRTCIPMNHLWPNQAPYTVCNSSL 720
            FGSLLKEGIHIRLSGQDVERGTFSHRHHVLHDQNVDKRTCIPMNHLWPNQAPYTVCNSSL
Sbjct: 661  FGSLLKEGIHIRLSGQDVERGTFSHRHHVLHDQNVDKRTCIPMNHLWPNQAPYTVCNSSL 720

Query: 721  SEYGVLGFELGFAMASPNALVLWEAQFGDFHNTAQCIIDQFICPGQAKWVRQNGIVLLLP 780
            SEYGVLGFELGFAMASPNALVLWEAQFGDFHNTAQCIIDQFICPGQAKWVRQNGIVLLLP
Sbjct: 721  SEYGVLGFELGFAMASPNALVLWEAQFGDFHNTAQCIIDQFICPGQAKWVRQNGIVLLLP 780

Query: 781  HGMEGMGPEHSSARPERFLQMCNDDPDVLPDLKEANFDINQLYDCNWVVVNCSTPGNFFH 840
            HGMEGMGPEHSSARPERFLQMCNDDPDVLPDLKEANFDINQLYDCNWVVVNCSTPGNFFH
Sbjct: 781  HGMEGMGPEHSSARPERFLQMCNDDPDVLPDLKEANFDINQLYDCNWVVVNCSTPGNFFH 840

Query: 841  VLRRQILLPFRKPLIIFTPKSLLRHPEARSSFDEMLPGTHFQRVIPEDGPAAQNPENVKR 900
            VLRRQILLPFRKPLIIFTPKSLLRHPEARSSFDEMLPGTHFQRVIPEDGPAAQNPENVKR
Sbjct: 841  VLRRQILLPFRKPLIIFTPKSLLRHPEARSSFDEMLPGTHFQRVIPEDGPAAQNPENVKR 900

Query: 901  LLFCTGKVYYDLTRERKARDMVGQVAITRIEQLSPFPFDLLLKEVQKYPNAELAWCQEEH 960
            LLFCTGKVYYDLTRERKARDMVGQVAITRIEQLSPFPFDLLLKEVQKYPNAELAWCQEEH
Sbjct: 901  LLFCTGKVYYDLTRERKARDMVGQVAITRIEQLSPFPFDLLLKEVQKYPNAELAWCQEEH 960

Query: 961  KNQGYYDYVKPRLRTTISRAKPVWYAGRDPAAAPATGNKKTHLTELQRLLDTAFDLDVFK 1020
            KNQGYYDYVKPRLRTTISRAKPVWYAGRDPAAAPATGNKKTHLTELQRLLDTAFDLDVFK
Sbjct: 961  KNQGYYDYVKPRLRTTISRAKPVWYAGRDPAAAPATGNKKTHLTELQRLLDTAFDLDVFK 1020

Query: 1021 NFS 1023
            NFS
Sbjct: 1021 NFS 1023


>gi|221316661 oxoglutarate dehydrogenase-like isoform a [Homo sapiens]
          Length = 1010

 Score = 1612 bits (4173), Expect = 0.0
 Identities = 770/981 (78%), Positives = 866/981 (88%), Gaps = 9/981 (0%)

Query: 41   SAPVAAEPFLSGTS-SNYVEEMYCAWLENPKSVHKSWDIFFRNTNAGAPPGTAYQSPLPL 99
            S P A  P   G   S+Y+EEMY AWLENP+SVHKSWD FFR  +  A  G+A   P   
Sbjct: 34   SGPPATFPSSKGGGGSSYMEEMYFAWLENPQSVHKSWDSFFREASEEAFSGSAQPRPP-- 91

Query: 100  SRGSLAAVAHAQSLVEAQPNVDKLVEDHLAVQSLIRAYQIRGHHVAQLDPLGILDADLDS 159
                 + V  ++S V ++    KLVEDHLAVQSLIRAYQIRGHHVAQLDPLGILDADLDS
Sbjct: 92   -----SVVHESRSAVSSRTKTSKLVEDHLAVQSLIRAYQIRGHHVAQLDPLGILDADLDS 146

Query: 160  SVPADIISSTDKLGFYGLDESDLDKVFHLPTTTFIGGQESALPLREIIRRLEMAYCQHIG 219
             VP+D+I++ DKL FY L E+DLDK F LPTTTFIGG E+ L LREIIRRLE  YCQHIG
Sbjct: 147  FVPSDLITTIDKLAFYDLQEADLDKEFQLPTTTFIGGSENTLSLREIIRRLENTYCQHIG 206

Query: 220  VEFMFINDLEQCQWIRQKFETPGIMQFTNEEKRTLLARLVRSTRFEEFLQRKWSSEKRFG 279
            +EFMFIND+EQCQWIRQKFETPG+MQF++EEKRTLLARLVRS RFE+FL RKWSSEKRFG
Sbjct: 207  LEFMFINDVEQCQWIRQKFETPGVMQFSSEEKRTLLARLVRSMRFEDFLARKWSSEKRFG 266

Query: 280  LEGCEVLIPALKTIIDKSSENGVDYVIMGMPHRGRLNVLANVIRKELEQIFCQFDSKLEA 339
            LEGCEV+IPALKTIIDKSSE G++ VI+GMPHRGRLNVLANVIRK+LEQIFCQFD KLEA
Sbjct: 267  LEGCEVMIPALKTIIDKSSEMGIENVILGMPHRGRLNVLANVIRKDLEQIFCQFDPKLEA 326

Query: 340  ADEGSGDVKYHLGMYHRRINRVTDRNITLSLVANPSHLEAADPVVMGKTKAEQFYCGDTE 399
            ADEGSGDVKYHLGMYH RINRVT+RNITLSLVANPSHLEA DPVV GKTKAEQFY GD +
Sbjct: 327  ADEGSGDVKYHLGMYHERINRVTNRNITLSLVANPSHLEAVDPVVQGKTKAEQFYRGDAQ 386

Query: 400  GKKVMSILLHGDAAFAGQGIVYETFHLSDLPSYTTHGTVHVVVNNQIGFTTDPRMARSSP 459
            GKKVMSIL+HGDAAFAGQG+VYETFHLSDLPSYTT+GTVHVVVNNQIGFTTDPRMARSSP
Sbjct: 387  GKKVMSILVHGDAAFAGQGVVYETFHLSDLPSYTTNGTVHVVVNNQIGFTTDPRMARSSP 446

Query: 460  YPTDVARVVNAPIFHVNSDDPEAVMYVCKVAAEWRSTFHKDVVVDLVCYRRNGHNEMDEP 519
            YPTDVARVVNAPIFHVN+DDPEAV+YVC VAAEWR+TF+KDVVVDLVCYRR GHNEMDEP
Sbjct: 447  YPTDVARVVNAPIFHVNADDPEAVIYVCSVAAEWRNTFNKDVVVDLVCYRRRGHNEMDEP 506

Query: 520  MFTQPLMYKQIRKQKPVLQKYAELLVSQGVVNQPEYEEEISKYDKICEEAFARSKDEKIL 579
            MFTQPLMYKQI +Q PVL+KYA+ L+++G V   E+EEEI+KYD+ICEEA+ RSKD+KIL
Sbjct: 507  MFTQPLMYKQIHRQVPVLKKYADKLIAEGTVTLQEFEEEIAKYDRICEEAYGRSKDKKIL 566

Query: 580  HIKHWLDSPWPGFFTLDGQPRSMSCPSTGLTEDILTHIGNVASSVPVENFTIHGGLSRIL 639
            HIKHWLDSPWPGFF +DG+P+SM+CP+TG+ ED+LTHIG+VASSVP+E+F IH GLSRIL
Sbjct: 567  HIKHWLDSPWPGFFNVDGEPKSMTCPATGIPEDMLTHIGSVASSVPLEDFKIHTGLSRIL 626

Query: 640  KTRGEMVKNRTVDWALAEYMAFGSLLKEGIHIRLSGQDVERGTFSHRHHVLHDQNVDKRT 699
            + R +M KNRTVDWALAEYMAFGSLLKEGIH+RLSGQDVERGTFSHRHHVLHDQ VD+RT
Sbjct: 627  RGRADMTKNRTVDWALAEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQEVDRRT 686

Query: 700  CIPMNHLWPNQAPYTVCNSSLSEYGVLGFELGFAMASPNALVLWEAQFGDFHNTAQCIID 759
            C+PMNHLWP+QAPYTVCNSSLSEYGVLGFELG+AMASPNALVLWEAQFGDFHNTAQCIID
Sbjct: 687  CVPMNHLWPDQAPYTVCNSSLSEYGVLGFELGYAMASPNALVLWEAQFGDFHNTAQCIID 746

Query: 760  QFICPGQAKWVRQNGIVLLLPHGMEGMGPEHSSARPERFLQMCNDDPDVLPDLKEANFDI 819
            QFI  GQAKWVR NGIVLLLPHGMEGMGPEHSSARPERFLQM NDD D  P   + +F++
Sbjct: 747  QFISTGQAKWVRHNGIVLLLPHGMEGMGPEHSSARPERFLQMSNDDSDAYPAFTK-DFEV 805

Query: 820  NQLYDCNWVVVNCSTPGNFFHVLRRQILLPFRKPLIIFTPKSLLRHPEARSSFDEMLPGT 879
            +QLYDCNW+VVNCSTP N+FHVLRRQILLPFRKPLIIFTPKSLLRHPEA+SSFD+M+ GT
Sbjct: 806  SQLYDCNWIVVNCSTPANYFHVLRRQILLPFRKPLIIFTPKSLLRHPEAKSSFDQMVSGT 865

Query: 880  HFQRVIPEDGPAAQNPENVKRLLFCTGKVYYDLTRERKARDMVGQVAITRIEQLSPFPFD 939
             FQRVIPEDG AA+ PE V+RL+FCTGKVYYDL +ER ++D+  +VAITR+EQ+SPFPFD
Sbjct: 866  SFQRVIPEDGAAARAPEQVQRLIFCTGKVYYDLVKERSSQDLEEKVAITRLEQISPFPFD 925

Query: 940  LLLKEVQKYPNAELAWCQEEHKNQGYYDYVKPRLRTTISRAKPVWYAGRDPAAAPATGNK 999
            L+ +E +KYP AELAWCQEEHKN GYYDY+ PR  T + RA+P+WY GRDPAAAPATGN+
Sbjct: 926  LIKQEAEKYPGAELAWCQEEHKNMGYYDYISPRFMTILRRARPIWYVGRDPAAAPATGNR 985

Query: 1000 KTHLTELQRLLDTAFDLDVFK 1020
             THL  L++ LDTAF+L  F+
Sbjct: 986  NTHLVSLKKFLDTAFNLQAFE 1006


>gi|221316665 oxoglutarate dehydrogenase-like isoform b [Homo sapiens]
          Length = 953

 Score = 1528 bits (3957), Expect = 0.0
 Identities = 719/884 (81%), Positives = 807/884 (91%), Gaps = 1/884 (0%)

Query: 137  YQIRGHHVAQLDPLGILDADLDSSVPADIISSTDKLGFYGLDESDLDKVFHLPTTTFIGG 196
            ++IRGHHVAQLDPLGILDADLDS VP+D+I++ DKL FY L E+DLDK F LPTTTFIGG
Sbjct: 67   HKIRGHHVAQLDPLGILDADLDSFVPSDLITTIDKLAFYDLQEADLDKEFQLPTTTFIGG 126

Query: 197  QESALPLREIIRRLEMAYCQHIGVEFMFINDLEQCQWIRQKFETPGIMQFTNEEKRTLLA 256
             E+ L LREIIRRLE  YCQHIG+EFMFIND+EQCQWIRQKFETPG+MQF++EEKRTLLA
Sbjct: 127  SENTLSLREIIRRLENTYCQHIGLEFMFINDVEQCQWIRQKFETPGVMQFSSEEKRTLLA 186

Query: 257  RLVRSTRFEEFLQRKWSSEKRFGLEGCEVLIPALKTIIDKSSENGVDYVIMGMPHRGRLN 316
            RLVRS RFE+FL RKWSSEKRFGLEGCEV+IPALKTIIDKSSE G++ VI+GMPHRGRLN
Sbjct: 187  RLVRSMRFEDFLARKWSSEKRFGLEGCEVMIPALKTIIDKSSEMGIENVILGMPHRGRLN 246

Query: 317  VLANVIRKELEQIFCQFDSKLEAADEGSGDVKYHLGMYHRRINRVTDRNITLSLVANPSH 376
            VLANVIRK+LEQIFCQFD KLEAADEGSGDVKYHLGMYH RINRVT+RNITLSLVANPSH
Sbjct: 247  VLANVIRKDLEQIFCQFDPKLEAADEGSGDVKYHLGMYHERINRVTNRNITLSLVANPSH 306

Query: 377  LEAADPVVMGKTKAEQFYCGDTEGKKVMSILLHGDAAFAGQGIVYETFHLSDLPSYTTHG 436
            LEA DPVV GKTKAEQFY GD +GKKVMSIL+HGDAAFAGQG+VYETFHLSDLPSYTT+G
Sbjct: 307  LEAVDPVVQGKTKAEQFYRGDAQGKKVMSILVHGDAAFAGQGVVYETFHLSDLPSYTTNG 366

Query: 437  TVHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNSDDPEAVMYVCKVAAEWRST 496
            TVHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVN+DDPEAV+YVC VAAEWR+T
Sbjct: 367  TVHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNADDPEAVIYVCSVAAEWRNT 426

Query: 497  FHKDVVVDLVCYRRNGHNEMDEPMFTQPLMYKQIRKQKPVLQKYAELLVSQGVVNQPEYE 556
            F+KDVVVDLVCYRR GHNEMDEPMFTQPLMYKQI +Q PVL+KYA+ L+++G V   E+E
Sbjct: 427  FNKDVVVDLVCYRRRGHNEMDEPMFTQPLMYKQIHRQVPVLKKYADKLIAEGTVTLQEFE 486

Query: 557  EEISKYDKICEEAFARSKDEKILHIKHWLDSPWPGFFTLDGQPRSMSCPSTGLTEDILTH 616
            EEI+KYD+ICEEA+ RSKD+KILHIKHWLDSPWPGFF +DG+P+SM+CP+TG+ ED+LTH
Sbjct: 487  EEIAKYDRICEEAYGRSKDKKILHIKHWLDSPWPGFFNVDGEPKSMTCPATGIPEDMLTH 546

Query: 617  IGNVASSVPVENFTIHGGLSRILKTRGEMVKNRTVDWALAEYMAFGSLLKEGIHIRLSGQ 676
            IG+VASSVP+E+F IH GLSRIL+ R +M KNRTVDWALAEYMAFGSLLKEGIH+RLSGQ
Sbjct: 547  IGSVASSVPLEDFKIHTGLSRILRGRADMTKNRTVDWALAEYMAFGSLLKEGIHVRLSGQ 606

Query: 677  DVERGTFSHRHHVLHDQNVDKRTCIPMNHLWPNQAPYTVCNSSLSEYGVLGFELGFAMAS 736
            DVERGTFSHRHHVLHDQ VD+RTC+PMNHLWP+QAPYTVCNSSLSEYGVLGFELG+AMAS
Sbjct: 607  DVERGTFSHRHHVLHDQEVDRRTCVPMNHLWPDQAPYTVCNSSLSEYGVLGFELGYAMAS 666

Query: 737  PNALVLWEAQFGDFHNTAQCIIDQFICPGQAKWVRQNGIVLLLPHGMEGMGPEHSSARPE 796
            PNALVLWEAQFGDFHNTAQCIIDQFI  GQAKWVR NGIVLLLPHGMEGMGPEHSSARPE
Sbjct: 667  PNALVLWEAQFGDFHNTAQCIIDQFISTGQAKWVRHNGIVLLLPHGMEGMGPEHSSARPE 726

Query: 797  RFLQMCNDDPDVLPDLKEANFDINQLYDCNWVVVNCSTPGNFFHVLRRQILLPFRKPLII 856
            RFLQM NDD D  P   + +F+++QLYDCNW+VVNCSTP N+FHVLRRQILLPFRKPLII
Sbjct: 727  RFLQMSNDDSDAYPAFTK-DFEVSQLYDCNWIVVNCSTPANYFHVLRRQILLPFRKPLII 785

Query: 857  FTPKSLLRHPEARSSFDEMLPGTHFQRVIPEDGPAAQNPENVKRLLFCTGKVYYDLTRER 916
            FTPKSLLRHPEA+SSFD+M+ GT FQRVIPEDG AA+ PE V+RL+FCTGKVYYDL +ER
Sbjct: 786  FTPKSLLRHPEAKSSFDQMVSGTSFQRVIPEDGAAARAPEQVQRLIFCTGKVYYDLVKER 845

Query: 917  KARDMVGQVAITRIEQLSPFPFDLLLKEVQKYPNAELAWCQEEHKNQGYYDYVKPRLRTT 976
             ++D+  +VAITR+EQ+SPFPFDL+ +E +KYP AELAWCQEEHKN GYYDY+ PR  T 
Sbjct: 846  SSQDLEEKVAITRLEQISPFPFDLIKQEAEKYPGAELAWCQEEHKNMGYYDYISPRFMTI 905

Query: 977  ISRAKPVWYAGRDPAAAPATGNKKTHLTELQRLLDTAFDLDVFK 1020
            + RA+P+WY GRDPAAAPATGN+ THL  L++ LDTAF+L  F+
Sbjct: 906  LRRARPIWYVGRDPAAAPATGNRNTHLVSLKKFLDTAFNLQAFE 949


>gi|221316669 oxoglutarate dehydrogenase-like isoform c [Homo sapiens]
          Length = 801

 Score = 1396 bits (3613), Expect = 0.0
 Identities = 654/798 (81%), Positives = 733/798 (91%), Gaps = 1/798 (0%)

Query: 223  MFINDLEQCQWIRQKFETPGIMQFTNEEKRTLLARLVRSTRFEEFLQRKWSSEKRFGLEG 282
            MFIND+EQCQWIRQKFETPG+MQF++EEKRTLLARLVRS RFE+FL RKWSSEKRFGLEG
Sbjct: 1    MFINDVEQCQWIRQKFETPGVMQFSSEEKRTLLARLVRSMRFEDFLARKWSSEKRFGLEG 60

Query: 283  CEVLIPALKTIIDKSSENGVDYVIMGMPHRGRLNVLANVIRKELEQIFCQFDSKLEAADE 342
            CEV+IPALKTIIDKSSE G++ VI+GMPHRGRLNVLANVIRK+LEQIFCQFD KLEAADE
Sbjct: 61   CEVMIPALKTIIDKSSEMGIENVILGMPHRGRLNVLANVIRKDLEQIFCQFDPKLEAADE 120

Query: 343  GSGDVKYHLGMYHRRINRVTDRNITLSLVANPSHLEAADPVVMGKTKAEQFYCGDTEGKK 402
            GSGDVKYHLGMYH RINRVT+RNITLSLVANPSHLEA DPVV GKTKAEQFY GD +GKK
Sbjct: 121  GSGDVKYHLGMYHERINRVTNRNITLSLVANPSHLEAVDPVVQGKTKAEQFYRGDAQGKK 180

Query: 403  VMSILLHGDAAFAGQGIVYETFHLSDLPSYTTHGTVHVVVNNQIGFTTDPRMARSSPYPT 462
            VMSIL+HGDAAFAGQG+VYETFHLSDLPSYTT+GTVHVVVNNQIGFTTDPRMARSSPYPT
Sbjct: 181  VMSILVHGDAAFAGQGVVYETFHLSDLPSYTTNGTVHVVVNNQIGFTTDPRMARSSPYPT 240

Query: 463  DVARVVNAPIFHVNSDDPEAVMYVCKVAAEWRSTFHKDVVVDLVCYRRNGHNEMDEPMFT 522
            DVARVVNAPIFHVN+DDPEAV+YVC VAAEWR+TF+KDVVVDLVCYRR GHNEMDEPMFT
Sbjct: 241  DVARVVNAPIFHVNADDPEAVIYVCSVAAEWRNTFNKDVVVDLVCYRRRGHNEMDEPMFT 300

Query: 523  QPLMYKQIRKQKPVLQKYAELLVSQGVVNQPEYEEEISKYDKICEEAFARSKDEKILHIK 582
            QPLMYKQI +Q PVL+KYA+ L+++G V   E+EEEI+KYD+ICEEA+ RSKD+KILHIK
Sbjct: 301  QPLMYKQIHRQVPVLKKYADKLIAEGTVTLQEFEEEIAKYDRICEEAYGRSKDKKILHIK 360

Query: 583  HWLDSPWPGFFTLDGQPRSMSCPSTGLTEDILTHIGNVASSVPVENFTIHGGLSRILKTR 642
            HWLDSPWPGFF +DG+P+SM+CP+TG+ ED+LTHIG+VASSVP+E+F IH GLSRIL+ R
Sbjct: 361  HWLDSPWPGFFNVDGEPKSMTCPATGIPEDMLTHIGSVASSVPLEDFKIHTGLSRILRGR 420

Query: 643  GEMVKNRTVDWALAEYMAFGSLLKEGIHIRLSGQDVERGTFSHRHHVLHDQNVDKRTCIP 702
             +M KNRTVDWALAEYMAFGSLLKEGIH+RLSGQDVERGTFSHRHHVLHDQ VD+RTC+P
Sbjct: 421  ADMTKNRTVDWALAEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQEVDRRTCVP 480

Query: 703  MNHLWPNQAPYTVCNSSLSEYGVLGFELGFAMASPNALVLWEAQFGDFHNTAQCIIDQFI 762
            MNHLWP+QAPYTVCNSSLSEYGVLGFELG+AMASPNALVLWEAQFGDFHNTAQCIIDQFI
Sbjct: 481  MNHLWPDQAPYTVCNSSLSEYGVLGFELGYAMASPNALVLWEAQFGDFHNTAQCIIDQFI 540

Query: 763  CPGQAKWVRQNGIVLLLPHGMEGMGPEHSSARPERFLQMCNDDPDVLPDLKEANFDINQL 822
              GQAKWVR NGIVLLLPHGMEGMGPEHSSARPERFLQM NDD D  P   + +F+++QL
Sbjct: 541  STGQAKWVRHNGIVLLLPHGMEGMGPEHSSARPERFLQMSNDDSDAYPAFTK-DFEVSQL 599

Query: 823  YDCNWVVVNCSTPGNFFHVLRRQILLPFRKPLIIFTPKSLLRHPEARSSFDEMLPGTHFQ 882
            YDCNW+VVNCSTP N+FHVLRRQILLPFRKPLIIFTPKSLLRHPEA+SSFD+M+ GT FQ
Sbjct: 600  YDCNWIVVNCSTPANYFHVLRRQILLPFRKPLIIFTPKSLLRHPEAKSSFDQMVSGTSFQ 659

Query: 883  RVIPEDGPAAQNPENVKRLLFCTGKVYYDLTRERKARDMVGQVAITRIEQLSPFPFDLLL 942
            RVIPEDG AA+ PE V+RL+FCTGKVYYDL +ER ++D+  +VAITR+EQ+SPFPFDL+ 
Sbjct: 660  RVIPEDGAAARAPEQVQRLIFCTGKVYYDLVKERSSQDLEEKVAITRLEQISPFPFDLIK 719

Query: 943  KEVQKYPNAELAWCQEEHKNQGYYDYVKPRLRTTISRAKPVWYAGRDPAAAPATGNKKTH 1002
            +E +KYP AELAWCQEEHKN GYYDY+ PR  T + RA+P+WY GRDPAAAPATGN+ TH
Sbjct: 720  QEAEKYPGAELAWCQEEHKNMGYYDYISPRFMTILRRARPIWYVGRDPAAAPATGNRNTH 779

Query: 1003 LTELQRLLDTAFDLDVFK 1020
            L  L++ LDTAF+L  F+
Sbjct: 780  LVSLKKFLDTAFNLQAFE 797


>gi|51873038 oxoglutarate (alpha-ketoglutarate) dehydrogenase
           (lipoamide) isoform 2 precursor [Homo sapiens]
          Length = 427

 Score =  811 bits (2096), Expect = 0.0
 Identities = 403/403 (100%), Positives = 403/403 (100%)

Query: 1   MFHLRTCAAKLRPLTASQTVKTFSQNRPAAARTFQQIRCYSAPVAAEPFLSGTSSNYVEE 60
           MFHLRTCAAKLRPLTASQTVKTFSQNRPAAARTFQQIRCYSAPVAAEPFLSGTSSNYVEE
Sbjct: 1   MFHLRTCAAKLRPLTASQTVKTFSQNRPAAARTFQQIRCYSAPVAAEPFLSGTSSNYVEE 60

Query: 61  MYCAWLENPKSVHKSWDIFFRNTNAGAPPGTAYQSPLPLSRGSLAAVAHAQSLVEAQPNV 120
           MYCAWLENPKSVHKSWDIFFRNTNAGAPPGTAYQSPLPLSRGSLAAVAHAQSLVEAQPNV
Sbjct: 61  MYCAWLENPKSVHKSWDIFFRNTNAGAPPGTAYQSPLPLSRGSLAAVAHAQSLVEAQPNV 120

Query: 121 DKLVEDHLAVQSLIRAYQIRGHHVAQLDPLGILDADLDSSVPADIISSTDKLGFYGLDES 180
           DKLVEDHLAVQSLIRAYQIRGHHVAQLDPLGILDADLDSSVPADIISSTDKLGFYGLDES
Sbjct: 121 DKLVEDHLAVQSLIRAYQIRGHHVAQLDPLGILDADLDSSVPADIISSTDKLGFYGLDES 180

Query: 181 DLDKVFHLPTTTFIGGQESALPLREIIRRLEMAYCQHIGVEFMFINDLEQCQWIRQKFET 240
           DLDKVFHLPTTTFIGGQESALPLREIIRRLEMAYCQHIGVEFMFINDLEQCQWIRQKFET
Sbjct: 181 DLDKVFHLPTTTFIGGQESALPLREIIRRLEMAYCQHIGVEFMFINDLEQCQWIRQKFET 240

Query: 241 PGIMQFTNEEKRTLLARLVRSTRFEEFLQRKWSSEKRFGLEGCEVLIPALKTIIDKSSEN 300
           PGIMQFTNEEKRTLLARLVRSTRFEEFLQRKWSSEKRFGLEGCEVLIPALKTIIDKSSEN
Sbjct: 241 PGIMQFTNEEKRTLLARLVRSTRFEEFLQRKWSSEKRFGLEGCEVLIPALKTIIDKSSEN 300

Query: 301 GVDYVIMGMPHRGRLNVLANVIRKELEQIFCQFDSKLEAADEGSGDVKYHLGMYHRRINR 360
           GVDYVIMGMPHRGRLNVLANVIRKELEQIFCQFDSKLEAADEGSGDVKYHLGMYHRRINR
Sbjct: 301 GVDYVIMGMPHRGRLNVLANVIRKELEQIFCQFDSKLEAADEGSGDVKYHLGMYHRRINR 360

Query: 361 VTDRNITLSLVANPSHLEAADPVVMGKTKAEQFYCGDTEGKKV 403
           VTDRNITLSLVANPSHLEAADPVVMGKTKAEQFYCGDTEGKKV
Sbjct: 361 VTDRNITLSLVANPSHLEAADPVVMGKTKAEQFYCGDTEGKKV 403


>gi|38788380 dehydrogenase E1 and transketolase domain containing 1
            [Homo sapiens]
          Length = 919

 Score =  574 bits (1480), Expect = e-163
 Identities = 360/933 (38%), Positives = 522/933 (55%), Gaps = 89/933 (9%)

Query: 115  EAQPNVDKLVEDHLAVQSLIRAYQIRGHHVAQLDPLGILDADLDSSVPADIISSTDKLGF 174
            E Q  +++   DH  +  L+  Y   GH  A+++PL    A L++      +  T     
Sbjct: 42   EPQGALERPPVDH-GLARLVTVYCEHGHKAAKINPLFTGQALLENVPEIQALVQT----- 95

Query: 175  YGLDESDLDKVFHLPTTTFIGGQESALPLREIIRRLEMAYCQHIGVEFMFINDLEQCQWI 234
                   L   FH      +G +E++L   E++  L   YC  I +E   +   ++  W 
Sbjct: 96   -------LQGPFHTAGLLNMGKEEASL--EEVLVYLNQIYCGQISIETSQLQSQDEKDWF 146

Query: 235  RQKFETPGIMQFTNEEKRTLLARLVRSTRFEEFLQRKWSSEKRFGLEGCEVLIPALKTII 294
             ++FE      FT EE++ L   ++ S  F+ FL  K+S+ KR+G EG E ++     ++
Sbjct: 147  AKRFEELQKETFTTEERKHLSKLMLESQEFDHFLATKFSTVKRYGGEGAESMMGFFHELL 206

Query: 295  DKSSENGVDYVIMGMPHRGRLNVLANVIRKELEQIFCQFDSKLEAADEGS--GDVKYHL- 351
              S+ +G+  VI+GMPHRGRLN+L  +++   E +F +     E  +  S  GDV  HL 
Sbjct: 207  KMSAYSGITDVIIGMPHRGRLNLLTGLLQFPPELMFRKMRGLSEFPENFSATGDVLSHLT 266

Query: 352  -------GMYHRRINRVTDRNITLSLVANPSHLEAADPVVMGKTKAEQFYCGDTE----- 399
                   G +H          + ++++ NPSHLEA +PV +GKT+  Q    D +     
Sbjct: 267  SSVDLYFGAHHP---------LHVTMLPNPSHLEAVNPVAVGKTRGRQQSRQDGDYSPDN 317

Query: 400  ----GKKVMSILLHGDAAFAGQGIVYETFHLSDLPSYTTHGTVHVVVNNQIGFTTDPRMA 455
                G +V+ + +HGDA+F GQGIV ETF LS+LP +   G+VH++VNNQ+G+TT     
Sbjct: 318  SAQPGDRVICLQVHGDASFCGQGIVPETFTLSNLPHFRIGGSVHLIVNNQLGYTTPAERG 377

Query: 456  RSSPYPTDVARVVNAPIFHVNSDDPEAVMYVCKVAAEWRSTFHKDVVVDLVCYRRNGHNE 515
            RSS Y +D+ ++V   I HVN D PE V+   ++A E++  F KDV++DL+CYR+ GHNE
Sbjct: 378  RSSLYCSDIGKLVGCAIIHVNGDSPEEVVRATRLAFEYQRQFRKDVIIDLLCYRQWGHNE 437

Query: 516  MDEPMFTQPLMYKQIRKQKPVLQKYAELLVSQGVVNQPEYEEEISKYDKICEEAFARSKD 575
            +DEP +T P+MYK IR +K +   YAE L++ G++ Q E  E  S Y       +A+  D
Sbjct: 438  LDEPFYTNPIMYKIIRARKSIPDTYAEHLIAGGLMTQEEVSEIKSSY-------YAKLND 490

Query: 576  EKILHIKHW------LDSPWPGFFTLDGQPRSMSCPSTGLTEDILTHIGNVASSVPVENF 629
              + ++ H+      L + W G    + Q   ++  STG+  D+L  +G  +  VP E  
Sbjct: 491  H-LNNMAHYRPPALNLQAHWQGLAQPEAQ---ITTWSTGVPLDLLRFVGMKSVEVPRE-L 545

Query: 630  TIHGGLSRILKTR-----GEMVKNRTVDWALAEYMAFGSLLKEGIHIRLSGQDVERGTFS 684
             +H   S +LKT       +M+    +DWA AE +A GSLL +G ++RLSGQDV RGTFS
Sbjct: 546  QMH---SHLLKTHVQSRMEKMMDGIKLDWATAEALALGSLLAQGFNVRLSGQDVGRGTFS 602

Query: 685  HRHHVLHDQNVDKRTCIPMNHLWPNQAPY-TVCNSSLSEYGVLGFELGFAMASPNALVLW 743
             RH ++  Q  D  T IP+NH+ PNQ  +  V NS LSE  VLGFE G ++ SP  L LW
Sbjct: 603  QRHAIVVCQETDD-TYIPLNHMDPNQKGFLEVSNSPLSEEAVLGFEYGMSIESPKLLPLW 661

Query: 744  EAQFGDFHNTAQCIIDQFICPGQAKWVRQNGIVLLLPHGMEGMGPEHSSARPERFLQMCN 803
            EAQFGDF N AQ I D FI  G+AKW+ Q+GIV+LLPHG +G GP+HSS R ERFLQMC 
Sbjct: 662  EAQFGDFFNGAQIIFDTFISGGEAKWLLQSGIVILLPHGYDGAGPDHSSCRIERFLQMC- 720

Query: 804  DDPDVLPDLKEANFDINQLYDCNWVVVNCSTPGNFFHVLRRQILLPFRKPLIIFTPKSLL 863
                   D  E   D + +   N  VV+ +TP  +FH+LRRQ++  FRKPLI+ +PK LL
Sbjct: 721  -------DSAEEGVDGDTV---NMFVVHPTTPAQYFHLLRRQMVRNFRKPLIVASPKMLL 770

Query: 864  RHPEARSSFDEMLPGTHFQRVIPEDGPAAQNPENVKRLLFCTGKVYYDLTRERKARD-MV 922
            R P A S+  EM PGT F  VI   G ++ +P+ VK L+FC+GK +Y L ++R++     
Sbjct: 771  RLPAAVSTLQEMAPGTTFNPVI---GDSSVDPKKVKTLVFCSGKHFYSLVKQRESLGAKK 827

Query: 923  GQVAITRIEQLSPFPFDLLLKEVQKYPNA-ELAWCQEEHKNQGYYDYVKPRLRTTISRAK 981
               AI R+E+L PFP D L +E+ KY +  +  W QEE +N G + +V PR    +  A 
Sbjct: 828  HDFAIIRVEELCPFPLDSLQQEMSKYKHVKDHIWSQEEPQNMGPWSFVSPRFEKQL--AC 885

Query: 982  PVWYAGRDPAAAPATGNKKTHLTELQRLLDTAF 1014
             +   GR P   PA G    HL + + +L   F
Sbjct: 886  KLRLVGRPPLPVPAVGIGTVHLHQHEDILAKTF 918


>gi|4557353 branched chain keto acid dehydrogenase E1 beta precursor
           [Homo sapiens]
          Length = 392

 Score = 37.0 bits (84), Expect = 0.095
 Identities = 31/103 (30%), Positives = 46/103 (44%), Gaps = 13/103 (12%)

Query: 715 VCNSSLSEYGVLGFELGFAMASPNALVLWEAQFGDFHNTAQCIIDQFICPGQAKWVRQNG 774
           V N+ L E G++GF +G A+    A+   E QF D+   A    DQ +    AK+  ++G
Sbjct: 119 VFNTPLCEQGIVGFGIGIAVTGATAIA--EIQFADYIFPA---FDQIVNEA-AKYRYRSG 172

Query: 775 -------IVLLLPHGMEGMGPEHSSARPERFLQMCNDDPDVLP 810
                  + +  P G  G G  + S  PE F   C     V+P
Sbjct: 173 DLFNCGSLTIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIP 215


>gi|34101272 branched chain keto acid dehydrogenase E1 beta
           precursor [Homo sapiens]
          Length = 392

 Score = 37.0 bits (84), Expect = 0.095
 Identities = 31/103 (30%), Positives = 46/103 (44%), Gaps = 13/103 (12%)

Query: 715 VCNSSLSEYGVLGFELGFAMASPNALVLWEAQFGDFHNTAQCIIDQFICPGQAKWVRQNG 774
           V N+ L E G++GF +G A+    A+   E QF D+   A    DQ +    AK+  ++G
Sbjct: 119 VFNTPLCEQGIVGFGIGIAVTGATAIA--EIQFADYIFPA---FDQIVNEA-AKYRYRSG 172

Query: 775 -------IVLLLPHGMEGMGPEHSSARPERFLQMCNDDPDVLP 810
                  + +  P G  G G  + S  PE F   C     V+P
Sbjct: 173 DLFNCGSLTIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIP 215


>gi|4505685 pyruvate dehydrogenase E1 alpha 1 precursor [Homo
           sapiens]
          Length = 390

 Score = 36.6 bits (83), Expect = 0.12
 Identities = 39/172 (22%), Positives = 77/172 (44%), Gaps = 9/172 (5%)

Query: 400 GKKVMSILLHGDAAFAGQGIVYETFHLSDLPSYTTHGTVHVVVNNQIGFTTD-PRMARSS 458
           GK  + + L+GD A A QG ++E ++++ L        + +  NN+ G  T   R A S+
Sbjct: 185 GKDEVCLTLYGDGA-ANQGQIFEAYNMAALWKLPC---IFICENNRYGMGTSVERAAAST 240

Query: 459 PYPTDVARVVNAPIFHVNSDDPEAVMYVCKVAAEWRSTFHKDVVVDLVCYRRNGHNEMDE 518
            Y     R    P   V+  D   V    + AA +  +    ++++L  YR +GH+  D 
Sbjct: 241 DY---YKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDP 297

Query: 519 PM-FTQPLMYKQIRKQKPVLQKYAELLVSQGVVNQPEYEEEISKYDKICEEA 569
            + +      +++R +   +    + +V+  + +  E +E   +  K  E+A
Sbjct: 298 GVSYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDA 349


>gi|4885543 pyruvate dehydrogenase E1 alpha 2 [Homo sapiens]
          Length = 388

 Score = 36.2 bits (82), Expect = 0.16
 Identities = 34/120 (28%), Positives = 54/120 (45%), Gaps = 8/120 (6%)

Query: 399 EGKKVMSILLHGDAAFAGQGIVYETFHLSDLPSYTTHGTVHVVVNNQIGFTTDPRMARSS 458
           +G   + + L+GD A A QG + E F+++ L        V +  NN  G  T    A +S
Sbjct: 182 KGNDEICLTLYGDGA-ANQGQIAEAFNMAALWKLPC---VFICENNLYGMGTSTERAAAS 237

Query: 459 PYPTDVARVVN-APIFHVNSDDPEAVMYVCKVAAEWRSTFHKDVVVDLVCYRRNGHNEMD 517
           P   D  +  N  P   V+  D   V    K AA +  +    ++++L  YR +GH+  D
Sbjct: 238 P---DYYKRGNFIPGLKVDGMDVLCVREATKFAANYCRSGKGPILMELQTYRYHGHSMSD 294


>gi|224586880 Ras protein-specific guanine nucleotide-releasing
           factor 1 isoform 3 [Homo sapiens]
          Length = 1257

 Score = 35.0 bits (79), Expect = 0.36
 Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 3/97 (3%)

Query: 255 LARLVRSTRFEEFLQRKWSSEKRFGLEGCEVLIPALKTIIDKSSENGVDYVIMGMPHRGR 314
           L+R++     E    RK  + +R  +EGCE+L+   +T + + S   V     G   RGR
Sbjct: 419 LSRIMHDEVSETENIRKNLAIERMIIEGCEILLDTSQTFVRQGSLIQVPMSEKGKITRGR 478

Query: 315 LNVLANVIRKELEQIFCQFDSKLEAADEGSGDVKYHL 351
           L  L+  ++KE E+    F   L     GSG  K HL
Sbjct: 479 LGSLS--LKKEGERQCFLFSKHLIICTRGSGG-KLHL 512


>gi|24797099 Ras protein-specific guanine nucleotide-releasing
           factor 1 isoform 1 [Homo sapiens]
          Length = 1273

 Score = 35.0 bits (79), Expect = 0.36
 Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 3/97 (3%)

Query: 255 LARLVRSTRFEEFLQRKWSSEKRFGLEGCEVLIPALKTIIDKSSENGVDYVIMGMPHRGR 314
           L+R++     E    RK  + +R  +EGCE+L+   +T + + S   V     G   RGR
Sbjct: 419 LSRIMHDEVSETENIRKNLAIERMIIEGCEILLDTSQTFVRQGSLIQVPMSEKGKITRGR 478

Query: 315 LNVLANVIRKELEQIFCQFDSKLEAADEGSGDVKYHL 351
           L  L+  ++KE E+    F   L     GSG  K HL
Sbjct: 479 LGSLS--LKKEGERQCFLFSKHLIICTRGSGG-KLHL 512


>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
          Length = 1684

 Score = 34.3 bits (77), Expect = 0.62
 Identities = 28/92 (30%), Positives = 42/92 (45%), Gaps = 17/92 (18%)

Query: 503 VDLVCYRRNGHNEMDEPMFTQPLMYKQIRKQKPVLQKYAELLV-------SQGVVNQP-- 553
           V   C +   HNE ++    +    K + +QK +  + AEL++       S  V N P  
Sbjct: 885 VSQTCSKSEIHNEKEKCFIKEHENLKPLLEQKELRDRRAELILLKDSLAKSPSVKNDPLS 944

Query: 554 ---EYEEEISKYDKICEEAFARSKDEKILHIK 582
              E EE+I   +K C+E     K+EKI  IK
Sbjct: 945 SVKELEEKIENLEKECKE-----KEEKINKIK 971


>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
          Length = 3571

 Score = 30.4 bits (67), Expect = 8.9
 Identities = 22/88 (25%), Positives = 40/88 (45%), Gaps = 1/88 (1%)

Query: 845  QILLPFRKPLIIFTPKSLLRHPEARSSFDEMLPGTHFQRVIPEDGPAAQNPENVKRLLFC 904
            Q L P   P    TP++LL+  + +  F   +PGT F  + P+ G        +  +   
Sbjct: 1667 QFLNPAFLPHFPMTPEALLQFQQPQFLFPFYIPGTEFS-LGPDLGLPGSATFGMPGMTGM 1725

Query: 905  TGKVYYDLTRERKARDMVGQVAITRIEQ 932
             G +  DL ++ + +  VGQ  +  ++Q
Sbjct: 1726 AGSLLEDLKQQIQTQHHVGQTQLQILQQ 1753


>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin
           (with transmembrane signal), 1 [Homo sapiens]
          Length = 3259

 Score = 30.4 bits (67), Expect = 8.9
 Identities = 22/65 (33%), Positives = 33/65 (50%), Gaps = 8/65 (12%)

Query: 537 LQKYAELLVSQG---VVNQPEYEEEISKYDKICEEAFARSKDEKILHIKHWLDSPWPGFF 593
           L KY E + +QG   +  +P+ EE++SK+DK   E     ++ +I  IKH L        
Sbjct: 107 LNKYIEEMKAQGGTVLPTEPQSEEQLSKHDKSSTE-----EEMEIEKIKHKLQEKEELIS 161

Query: 594 TLDGQ 598
           TL  Q
Sbjct: 162 TLQAQ 166


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.418 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,875,703
Number of Sequences: 37866
Number of extensions: 1906710
Number of successful extensions: 3997
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 3966
Number of HSP's gapped (non-prelim): 22
length of query: 1023
length of database: 18,247,518
effective HSP length: 112
effective length of query: 911
effective length of database: 14,006,526
effective search space: 12759945186
effective search space used: 12759945186
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.