Guide to the Human Genome
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Search of human proteins with 51873031

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|51873031 nicalin [Homo sapiens]
         (563 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|51873031 nicalin [Homo sapiens]                                   1101   0.0  
gi|33589848 transferrin receptor 2 [Homo sapiens]                      41   0.003
gi|189458819 transferrin receptor [Homo sapiens]                       39   0.013
gi|189458817 transferrin receptor [Homo sapiens]                       39   0.013
gi|4885505 N-acetylated alpha-linked acidic dipeptidase 2 [Homo ...    33   0.70 
gi|14251212 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 [Homo sapi...    33   0.91 
gi|121114306 neurogenic differentiation 1 [Homo sapiens]               32   1.2  
gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens]            32   1.2  
gi|164519122 LGN protein [Homo sapiens]                                30   5.9  

>gi|51873031 nicalin [Homo sapiens]
          Length = 563

 Score = 1101 bits (2848), Expect = 0.0
 Identities = 563/563 (100%), Positives = 563/563 (100%)

Query: 1   MLEEAGEVLENMLKASCLPLGFIVFLPAVLLLVAPPLPAADAAHEFTVYRMQQYDLQGQP 60
           MLEEAGEVLENMLKASCLPLGFIVFLPAVLLLVAPPLPAADAAHEFTVYRMQQYDLQGQP
Sbjct: 1   MLEEAGEVLENMLKASCLPLGFIVFLPAVLLLVAPPLPAADAAHEFTVYRMQQYDLQGQP 60

Query: 61  YGTRNAVLNTEARTMAAEVLSRRCVLMRLLDFSYEQYQKALRQSAGAVVIILPRAMAAVP 120
           YGTRNAVLNTEARTMAAEVLSRRCVLMRLLDFSYEQYQKALRQSAGAVVIILPRAMAAVP
Sbjct: 61  YGTRNAVLNTEARTMAAEVLSRRCVLMRLLDFSYEQYQKALRQSAGAVVIILPRAMAAVP 120

Query: 121 QDVVRQFMEIEPEMLAMETAVPVYFAVEDEALLSIYKQTQAASASQGSASAAEVLLRTAT 180
           QDVVRQFMEIEPEMLAMETAVPVYFAVEDEALLSIYKQTQAASASQGSASAAEVLLRTAT
Sbjct: 121 QDVVRQFMEIEPEMLAMETAVPVYFAVEDEALLSIYKQTQAASASQGSASAAEVLLRTAT 180

Query: 181 ANGFQMVTSGVQSKAVSDWLIASVEGRLTGLGGEDLPTIVIVAHYDAFGVAPWLSLGADS 240
           ANGFQMVTSGVQSKAVSDWLIASVEGRLTGLGGEDLPTIVIVAHYDAFGVAPWLSLGADS
Sbjct: 181 ANGFQMVTSGVQSKAVSDWLIASVEGRLTGLGGEDLPTIVIVAHYDAFGVAPWLSLGADS 240

Query: 241 NGSGVSVLLELARLFSRLYTYKRTHAAYNLLFFASGGGKFNYQGTKRWLEDNLDHTDSSL 300
           NGSGVSVLLELARLFSRLYTYKRTHAAYNLLFFASGGGKFNYQGTKRWLEDNLDHTDSSL
Sbjct: 241 NGSGVSVLLELARLFSRLYTYKRTHAAYNLLFFASGGGKFNYQGTKRWLEDNLDHTDSSL 300

Query: 301 LQDNVAFVLCLDTVGRGSSLHLHVSKPPREGTLQHAFLRELETVAAHQFPEVRFSMVHKR 360
           LQDNVAFVLCLDTVGRGSSLHLHVSKPPREGTLQHAFLRELETVAAHQFPEVRFSMVHKR
Sbjct: 301 LQDNVAFVLCLDTVGRGSSLHLHVSKPPREGTLQHAFLRELETVAAHQFPEVRFSMVHKR 360

Query: 361 INLAEDVLAWEHERFAIRRLPAFTLSHLESHRDGQRSSIMDVRSRVDSKTLTRNTRIIAE 420
           INLAEDVLAWEHERFAIRRLPAFTLSHLESHRDGQRSSIMDVRSRVDSKTLTRNTRIIAE
Sbjct: 361 INLAEDVLAWEHERFAIRRLPAFTLSHLESHRDGQRSSIMDVRSRVDSKTLTRNTRIIAE 420

Query: 421 ALTRVIYNLTEKGTPPDMPVFTEQMQIQQEQLDSVMDWLTNQPRAAQLVDKDSTFLSTLE 480
           ALTRVIYNLTEKGTPPDMPVFTEQMQIQQEQLDSVMDWLTNQPRAAQLVDKDSTFLSTLE
Sbjct: 421 ALTRVIYNLTEKGTPPDMPVFTEQMQIQQEQLDSVMDWLTNQPRAAQLVDKDSTFLSTLE 480

Query: 481 HHLSRYLKDVKQHHVKADKRDPEFVFYDQLKQVMNAYRVKPAVFDLLLAVGIAAYLGMAY 540
           HHLSRYLKDVKQHHVKADKRDPEFVFYDQLKQVMNAYRVKPAVFDLLLAVGIAAYLGMAY
Sbjct: 481 HHLSRYLKDVKQHHVKADKRDPEFVFYDQLKQVMNAYRVKPAVFDLLLAVGIAAYLGMAY 540

Query: 541 VAVQHFSLLYKTVQRLLVKAKTQ 563
           VAVQHFSLLYKTVQRLLVKAKTQ
Sbjct: 541 VAVQHFSLLYKTVQRLLVKAKTQ 563


>gi|33589848 transferrin receptor 2 [Homo sapiens]
          Length = 801

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 36/125 (28%), Positives = 55/125 (44%), Gaps = 13/125 (10%)

Query: 219 IVIVAHYDAFGVAPWLSLGADSNGSGVSVLLELARLFSRLYTYKRTHAAYNLLFFASGGG 278
           +VI A  DA+G       GA  +  G ++LLEL R FS + +        +LLF +  GG
Sbjct: 427 VVIGAQRDAWGP------GAAKSAVGTAILLELVRTFSSMVS-NGFRPRRSLLFISWDGG 479

Query: 279 KFNYQGTKRWLEDNLDHTDSSLLQDNVAFVLCLDTVGRGSSLHLHVSKPPREGTLQHAFL 338
            F   G+  WLE  L     S+L       + LD    G     H    P   +L  + L
Sbjct: 480 DFGSVGSTEWLEGYL-----SVLHLKAVVYVSLDNAVLGDD-KFHAKTSPLLTSLIESVL 533

Query: 339 RELET 343
           +++++
Sbjct: 534 KQVDS 538


>gi|189458819 transferrin receptor [Homo sapiens]
          Length = 760

 Score = 38.9 bits (89), Expect = 0.013
 Identities = 52/214 (24%), Positives = 84/214 (39%), Gaps = 16/214 (7%)

Query: 219 IVIVAHYDAFGVAPWLSLGADSNGSGVSVLLELARLFSRLYTYKRTHAAYNLLFFASGGG 278
           +V+ A  DA+G       GA  +G G ++LL+LA++FS +        + +++F +   G
Sbjct: 403 VVVGAQRDAWGP------GAAKSGVGTALLLKLAQMFSDMVLKDGFQPSRSIIFASWSAG 456

Query: 279 KFNYQGTKRWLEDNLDHTDSSLLQDNVAFVLCLDTVGRGSSLHLHVSKPPREGTLQHAFL 338
            F   G   WLE  L     S L       + LD    G+S +  VS  P   TL    +
Sbjct: 457 DFGSVGATEWLEGYL-----SSLHLKAFTYINLDKAVLGTS-NFKVSASPLLYTLIEKTM 510

Query: 339 RELETVAAHQFPEVRFSMVHKRINLAEDVLAWEHERFAIRRLPAFTLSHLESHRDGQRSS 398
           + ++     QF     +   K   L  D  A+     A   +PA +    E        +
Sbjct: 511 QNVKHPVTGQFLYQDSNWASKVEKLTLDNAAFPF--LAYSGIPAVSFCFCEDTDYPYLGT 568

Query: 399 IMDVRSRVDSK--TLTRNTRIIAEALTRVIYNLT 430
            MD    +  +   L +  R  AE   + +  LT
Sbjct: 569 TMDTYKELIERIPELNKVARAAAEVAGQFVIKLT 602


>gi|189458817 transferrin receptor [Homo sapiens]
          Length = 760

 Score = 38.9 bits (89), Expect = 0.013
 Identities = 52/214 (24%), Positives = 84/214 (39%), Gaps = 16/214 (7%)

Query: 219 IVIVAHYDAFGVAPWLSLGADSNGSGVSVLLELARLFSRLYTYKRTHAAYNLLFFASGGG 278
           +V+ A  DA+G       GA  +G G ++LL+LA++FS +        + +++F +   G
Sbjct: 403 VVVGAQRDAWGP------GAAKSGVGTALLLKLAQMFSDMVLKDGFQPSRSIIFASWSAG 456

Query: 279 KFNYQGTKRWLEDNLDHTDSSLLQDNVAFVLCLDTVGRGSSLHLHVSKPPREGTLQHAFL 338
            F   G   WLE  L     S L       + LD    G+S +  VS  P   TL    +
Sbjct: 457 DFGSVGATEWLEGYL-----SSLHLKAFTYINLDKAVLGTS-NFKVSASPLLYTLIEKTM 510

Query: 339 RELETVAAHQFPEVRFSMVHKRINLAEDVLAWEHERFAIRRLPAFTLSHLESHRDGQRSS 398
           + ++     QF     +   K   L  D  A+     A   +PA +    E        +
Sbjct: 511 QNVKHPVTGQFLYQDSNWASKVEKLTLDNAAFPF--LAYSGIPAVSFCFCEDTDYPYLGT 568

Query: 399 IMDVRSRVDSK--TLTRNTRIIAEALTRVIYNLT 430
            MD    +  +   L +  R  AE   + +  LT
Sbjct: 569 TMDTYKELIERIPELNKVARAAAEVAGQFVIKLT 602


>gi|4885505 N-acetylated alpha-linked acidic dipeptidase 2 [Homo
           sapiens]
          Length = 740

 Score = 33.1 bits (74), Expect = 0.70
 Identities = 22/75 (29%), Positives = 38/75 (50%), Gaps = 7/75 (9%)

Query: 219 IVIVAHYDAFGVAPWLSLGADSNGSGVSVLLELARLFSRLYTYKRTHAAYNLLFFASGGG 278
           +++  H D+     W+  GA    SGV+VL E+AR F +L + K       ++F +    
Sbjct: 362 VILGGHRDS-----WV-FGAIDPTSGVAVLQEIARSFGKLMS-KGWRPRRTIIFASWDAE 414

Query: 279 KFNYQGTKRWLEDNL 293
           +F   G+  W E+N+
Sbjct: 415 EFGLLGSTEWAEENV 429


>gi|14251212 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 [Homo
           sapiens]
          Length = 824

 Score = 32.7 bits (73), Expect = 0.91
 Identities = 17/80 (21%), Positives = 43/80 (53%), Gaps = 3/80 (3%)

Query: 447 IQQEQLDSVMDWL-TNQPRAAQLVDKDSTFLSTLEHHLSRYLKDVKQHHVKADKRDPEFV 505
           +++      ++W+ ++ P + Q++   +T+   L + L++Y++D     V+ +  DP  +
Sbjct: 217 LEEGSFQEQINWIYSSLPASKQMLAVSATYPEFLANALTKYMRDPT--FVRLNSSDPSLI 274

Query: 506 FYDQLKQVMNAYRVKPAVFD 525
              Q  +V+N+Y +   VF+
Sbjct: 275 GLKQYYKVVNSYPLAHKVFE 294


>gi|121114306 neurogenic differentiation 1 [Homo sapiens]
          Length = 356

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 20/54 (37%), Positives = 24/54 (44%)

Query: 13  LKASCLPLGFIVFLPAVLLLVAPPLPAADAAHEFTVYRMQQYDLQGQPYGTRNA 66
           L A CL L    FLP     + P LP A A+     Y  Q   L   PYGT ++
Sbjct: 183 LVAGCLQLNPRTFLPEQNQDMPPHLPTASASFPVHPYSYQSPGLPSPPYGTMDS 236


>gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens]
          Length = 4523

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 16/55 (29%), Positives = 28/55 (50%)

Query: 437 DMPVFTEQMQIQQEQLDSVMDWLTNQPRAAQLVDKDSTFLSTLEHHLSRYLKDVK 491
           + P+  ++++   EQL +   WLT Q      +++     S LEH + R  K+VK
Sbjct: 781 EYPLIEDELRAIDEQLTAATTWLTWQDDCWGYIERVRAATSELEHRVERTQKNVK 835


>gi|164519122 LGN protein [Homo sapiens]
          Length = 684

 Score = 30.0 bits (66), Expect = 5.9
 Identities = 19/81 (23%), Positives = 39/81 (48%), Gaps = 1/81 (1%)

Query: 430 TEKGTPPDMPVFTEQMQIQQEQLDSVMDWLTNQPRAAQLVDKDSTFLSTLEHHLSRYLKD 489
           T   TPP M + T  + +     D  +D L +  ++ +L D+ ++F +     L++  + 
Sbjct: 522 TTSSTPPKMMLKTSSVPVVSPNTDEFLDLLASS-QSRRLDDQRASFSNLPGLRLTQNSQS 580

Query: 490 VKQHHVKADKRDPEFVFYDQL 510
           V  H +  D ++ +  F+D L
Sbjct: 581 VLSHLMTNDNKEADEDFFDIL 601


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.133    0.383 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,786,647
Number of Sequences: 37866
Number of extensions: 764172
Number of successful extensions: 1765
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1758
Number of HSP's gapped (non-prelim): 11
length of query: 563
length of database: 18,247,518
effective HSP length: 107
effective length of query: 456
effective length of database: 14,195,856
effective search space: 6473310336
effective search space used: 6473310336
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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