Guide to the Human Genome
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Search of human proteins with 5174731

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5174731 translin-associated factor X [Homo sapiens]
         (290 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5174731 translin-associated factor X [Homo sapiens]                577   e-165
gi|4759270 translin [Homo sapiens]                                     65   5e-11
gi|22726201 inositol polyphosphate multikinase [Homo sapiens]          32   0.65 
gi|109255236 centrosomal protein 63 isoform d [Homo sapiens]           30   1.9  
gi|109255226 centrosomal protein 63 isoform c [Homo sapiens]           30   1.9  
gi|64085252 hypothetical protein LOC145508 [Homo sapiens]              30   2.5  
gi|189181750 human immunodeficiency virus type I enhancer bindin...    30   3.2  
gi|116089331 human immunodeficiency virus type I enhancer bindin...    30   3.2  
gi|70166430 GRINL1A combined protein isoform 2 [Homo sapiens]          28   7.2  
gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens]          28   7.2  
gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens]         28   7.2  
gi|70166580 GRINL1A upstream protein isoform 7 [Homo sapiens]          28   7.2  
gi|27436951 lamin B2 [Homo sapiens]                                    28   9.4  
gi|7710129 LIM domain only 6 [Homo sapiens]                            28   9.4  

>gi|5174731 translin-associated factor X [Homo sapiens]
          Length = 290

 Score =  577 bits (1488), Expect = e-165
 Identities = 290/290 (100%), Positives = 290/290 (100%)

Query: 1   MSNKEGSGGFRKRKHDNFPHNQRREGKDVNSSSPVMLAFKSFQQELDARHDKYERLVKLS 60
           MSNKEGSGGFRKRKHDNFPHNQRREGKDVNSSSPVMLAFKSFQQELDARHDKYERLVKLS
Sbjct: 1   MSNKEGSGGFRKRKHDNFPHNQRREGKDVNSSSPVMLAFKSFQQELDARHDKYERLVKLS 60

Query: 61  RDITVESKRTIFLLHRITSAPDMEDILTESEIKLDGVRQKIFQVAQELSGEDMHQFHRAI 120
           RDITVESKRTIFLLHRITSAPDMEDILTESEIKLDGVRQKIFQVAQELSGEDMHQFHRAI
Sbjct: 61  RDITVESKRTIFLLHRITSAPDMEDILTESEIKLDGVRQKIFQVAQELSGEDMHQFHRAI 120

Query: 121 TTGLQEYVEAVSFQHFIKTRSLISMDEINKQLIFTTEDNGKENKTPSSDAQDKQFGTWRL 180
           TTGLQEYVEAVSFQHFIKTRSLISMDEINKQLIFTTEDNGKENKTPSSDAQDKQFGTWRL
Sbjct: 121 TTGLQEYVEAVSFQHFIKTRSLISMDEINKQLIFTTEDNGKENKTPSSDAQDKQFGTWRL 180

Query: 181 RVTPVDYLLGVADLTGELMRMCINSVGNGDIDTPFEVSQFLRQVYDGFSFIGNTGPYEVS 240
           RVTPVDYLLGVADLTGELMRMCINSVGNGDIDTPFEVSQFLRQVYDGFSFIGNTGPYEVS
Sbjct: 181 RVTPVDYLLGVADLTGELMRMCINSVGNGDIDTPFEVSQFLRQVYDGFSFIGNTGPYEVS 240

Query: 241 KKLYTLKQSLAKVENACYALKVRGSEIPKHMLADVFSVKTEMIDQEEGIS 290
           KKLYTLKQSLAKVENACYALKVRGSEIPKHMLADVFSVKTEMIDQEEGIS
Sbjct: 241 KKLYTLKQSLAKVENACYALKVRGSEIPKHMLADVFSVKTEMIDQEEGIS 290


>gi|4759270 translin [Homo sapiens]
          Length = 228

 Score = 65.5 bits (158), Expect = 5e-11
 Identities = 57/229 (24%), Positives = 97/229 (42%), Gaps = 22/229 (9%)

Query: 39  FKSFQQELDARHDKYERLVKLSRDITVESKRTIFLLHRITSAPDMEDI---LTESEIKLD 95
           F   Q  L A  D  E + K+ + +   ++  + LL  +      +DI     ++     
Sbjct: 7   FVELQGFLAAEQDIREEIRKVVQSLEQTAREILTLLQGVHQGAGFQDIPKRCLKAREHFG 66

Query: 96  GVRQKIFQVAQELSGEDMHQFHRAITTGLQEYVEAVSFQHFIKTRSLISMDEINKQLIFT 155
            V+  +  +  +   E  ++FH      LQ  V   +F  +++T +L++ + +       
Sbjct: 67  TVKTHLTSLKTKFPAEQYYRFHEHWRFVLQRLVFLAAFVVYLETETLVTREAV------- 119

Query: 156 TEDNGKENKTPSSDAQDKQFGTWRLRVTPVDYLLGVADLTGELMRMCINSVGNGDIDTPF 215
           TE  G E         D++ G     +   DYL GV  L  EL R+ +NSV  GD   P 
Sbjct: 120 TEILGIE--------PDREKG---FHLDVEDYLSGVLILASELSRLSVNSVTAGDYSRPL 168

Query: 216 EVSQFLRQVYDGFSFIGNTGPYEVSKKLYTLKQSLAKVENACYALKVRG 264
            +S F+ ++  GF  + N     + K+   LK  + KVE   Y L +RG
Sbjct: 169 HISTFINELDSGFRLL-NLKNDSLRKRYDGLKYDVKKVEEVVYDLSIRG 216


>gi|22726201 inositol polyphosphate multikinase [Homo sapiens]
          Length = 416

 Score = 32.0 bits (71), Expect = 0.65
 Identities = 24/103 (23%), Positives = 41/103 (39%), Gaps = 6/103 (5%)

Query: 173 KQFGTWRLRVTPVDYLLGVADLTGELMRMCINSVGNGDID-TPFEVSQFLRQVYDGFSFI 231
           K +G W     P D  L + D+T +  + CI  V  G     PF  S+ ++Q    +  +
Sbjct: 112 KYYGIWSPPTAPNDLYLKLEDVTHKFNKPCIMDVKIGQKSYDPFASSEKIQQQVSKYPLM 171

Query: 232 GNTGPYEVSKKLYTLKQSLAKVENACYALKVRGSEIPKHMLAD 274
              G   +  ++Y +     + EN  Y     G  + K  + D
Sbjct: 172 EEIGFLVLGMRVYHVHSDSYETENQHY-----GRSLTKETIKD 209


>gi|109255236 centrosomal protein 63 isoform d [Homo sapiens]
          Length = 475

 Score = 30.4 bits (67), Expect = 1.9
 Identities = 35/135 (25%), Positives = 62/135 (45%), Gaps = 10/135 (7%)

Query: 22  QRREGKDVNSSSPVMLAFKSFQQELD---ARHDKYERLVKLSRDITVESKRTIFLLHRIT 78
           Q+ E  +++S S +       ++  D   A   + ERL     D+ V +  T+     + 
Sbjct: 193 QKLESVELSSQSEIQHLSSKLERANDTICANELEIERLTMRVNDL-VGTSMTV-----LQ 246

Query: 79  SAPDMEDILTESEIKLDGVRQKIFQVAQEL-SGEDMHQFHRAITTGLQEYVEAVSFQHFI 137
                E+ L ESE  L+ ++++  ++   L S E++    R     LQE V+A + QH +
Sbjct: 247 EQQQKEEKLRESEKLLEALQEEKRELKAALQSQENLIHEARIQKEKLQEKVKATNTQHAV 306

Query: 138 KTRSLISMDEINKQL 152
           +  SL S+    KQL
Sbjct: 307 EAISLESVSATCKQL 321


>gi|109255226 centrosomal protein 63 isoform c [Homo sapiens]
          Length = 495

 Score = 30.4 bits (67), Expect = 1.9
 Identities = 35/135 (25%), Positives = 62/135 (45%), Gaps = 10/135 (7%)

Query: 22  QRREGKDVNSSSPVMLAFKSFQQELD---ARHDKYERLVKLSRDITVESKRTIFLLHRIT 78
           Q+ E  +++S S +       ++  D   A   + ERL     D+ V +  T+     + 
Sbjct: 193 QKLESVELSSQSEIQHLSSKLERANDTICANELEIERLTMRVNDL-VGTSMTV-----LQ 246

Query: 79  SAPDMEDILTESEIKLDGVRQKIFQVAQEL-SGEDMHQFHRAITTGLQEYVEAVSFQHFI 137
                E+ L ESE  L+ ++++  ++   L S E++    R     LQE V+A + QH +
Sbjct: 247 EQQQKEEKLRESEKLLEALQEEKRELKAALQSQENLIHEARIQKEKLQEKVKATNTQHAV 306

Query: 138 KTRSLISMDEINKQL 152
           +  SL S+    KQL
Sbjct: 307 EAISLESVSATCKQL 321


>gi|64085252 hypothetical protein LOC145508 [Homo sapiens]
          Length = 1094

 Score = 30.0 bits (66), Expect = 2.5
 Identities = 29/130 (22%), Positives = 55/130 (42%), Gaps = 20/130 (15%)

Query: 21  NQRREGKDVNSSSPVMLAFKSFQQELDARHDKYERLVKLSRDITVESKRTIFLLHRITSA 80
           N R+E  DV +   +       ++EL ++ +K   +     D+ +E K ++  +HR+   
Sbjct: 541 NLRKELNDVLTKRALQ------EEELHSKEEKLRDIKSHQADLELEVKNSLDTIHRL--- 591

Query: 81  PDMEDILTESEIKLDGVRQKIFQVAQELSGEDMHQFHRAITTGLQEYVEAVSFQHFIKTR 140
                   ESE+K     Q   +V +    E++ +  +   +  Q+  + +  Q  IK  
Sbjct: 592 --------ESELKKQSKIQSQMKVEKAHLEEEIAELKK---SQAQDKAKLLEMQESIKDL 640

Query: 141 SLISMDEINK 150
           S I  D  NK
Sbjct: 641 SAIRADLANK 650


>gi|189181750 human immunodeficiency virus type I enhancer binding
           protein 3 b [Homo sapiens]
          Length = 2405

 Score = 29.6 bits (65), Expect = 3.2
 Identities = 19/65 (29%), Positives = 31/65 (47%), Gaps = 1/65 (1%)

Query: 119 AITTGLQEYVEAVSFQHFIKTRSLISMDEINKQLIFTTEDNGK-ENKTPSSDAQDKQFGT 177
           A ++G   +  +V         S +S+   ++   F  +D+GK E  +PSSD + K  GT
Sbjct: 914 AQSSGESSFESSVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGT 973

Query: 178 WRLRV 182
             L V
Sbjct: 974 HMLTV 978


>gi|116089331 human immunodeficiency virus type I enhancer binding
           protein 3 [Homo sapiens]
          Length = 2406

 Score = 29.6 bits (65), Expect = 3.2
 Identities = 19/65 (29%), Positives = 31/65 (47%), Gaps = 1/65 (1%)

Query: 119 AITTGLQEYVEAVSFQHFIKTRSLISMDEINKQLIFTTEDNGK-ENKTPSSDAQDKQFGT 177
           A ++G   +  +V         S +S+   ++   F  +D+GK E  +PSSD + K  GT
Sbjct: 914 AQSSGESSFESSVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGT 973

Query: 178 WRLRV 182
             L V
Sbjct: 974 HMLTV 978


>gi|70166430 GRINL1A combined protein isoform 2 [Homo sapiens]
          Length = 445

 Score = 28.5 bits (62), Expect = 7.2
 Identities = 34/140 (24%), Positives = 59/140 (42%), Gaps = 20/140 (14%)

Query: 95  DGVRQKIFQVAQELSGEDMHQFHRAITTGLQEYVE------AVSFQHFIKTRSLISMDEI 148
           D +RQKI Q+ QELS          ++   QEY+E      + +   F    S ++ D I
Sbjct: 123 DEMRQKIRQLTQELS----------VSHAQQEYLENHIQTQSSALDRFNAMNSALASDSI 172

Query: 149 --NKQLIFTTEDNGKENKTPSSDAQDKQFGTWRLRVTPVDYLLGVADLTGELMRMCINSV 206
              K L+  T +N        +  Q  +    +LR       L VA +  +L++M + S 
Sbjct: 173 GLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLR--EKQRQLEVAQVENQLLKMKVESS 230

Query: 207 GNGDIDTPFEVSQFLRQVYD 226
              + +   E+++ L   Y+
Sbjct: 231 QEANAEVMREMTKKLYSQYE 250


>gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens]
          Length = 550

 Score = 28.5 bits (62), Expect = 7.2
 Identities = 34/140 (24%), Positives = 59/140 (42%), Gaps = 20/140 (14%)

Query: 95  DGVRQKIFQVAQELSGEDMHQFHRAITTGLQEYVE------AVSFQHFIKTRSLISMDEI 148
           D +RQKI Q+ QELS          ++   QEY+E      + +   F    S ++ D I
Sbjct: 123 DEMRQKIRQLTQELS----------VSHAQQEYLENHIQTQSSALDRFNAMNSALASDSI 172

Query: 149 --NKQLIFTTEDNGKENKTPSSDAQDKQFGTWRLRVTPVDYLLGVADLTGELMRMCINSV 206
              K L+  T +N        +  Q  +    +LR       L VA +  +L++M + S 
Sbjct: 173 GLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLR--EKQRQLEVAQVENQLLKMKVESS 230

Query: 207 GNGDIDTPFEVSQFLRQVYD 226
              + +   E+++ L   Y+
Sbjct: 231 QEANAEVMREMTKKLYSQYE 250


>gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens]
          Length = 438

 Score = 28.5 bits (62), Expect = 7.2
 Identities = 34/140 (24%), Positives = 59/140 (42%), Gaps = 20/140 (14%)

Query: 95  DGVRQKIFQVAQELSGEDMHQFHRAITTGLQEYVE------AVSFQHFIKTRSLISMDEI 148
           D +RQKI Q+ QELS          ++   QEY+E      + +   F    S ++ D I
Sbjct: 123 DEMRQKIRQLTQELS----------VSHAQQEYLENHIQTQSSALDRFNAMNSALASDSI 172

Query: 149 --NKQLIFTTEDNGKENKTPSSDAQDKQFGTWRLRVTPVDYLLGVADLTGELMRMCINSV 206
              K L+  T +N        +  Q  +    +LR       L VA +  +L++M + S 
Sbjct: 173 GLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLR--EKQRQLEVAQVENQLLKMKVESS 230

Query: 207 GNGDIDTPFEVSQFLRQVYD 226
              + +   E+++ L   Y+
Sbjct: 231 QEANAEVMREMTKKLYSQYE 250


>gi|70166580 GRINL1A upstream protein isoform 7 [Homo sapiens]
          Length = 466

 Score = 28.5 bits (62), Expect = 7.2
 Identities = 34/140 (24%), Positives = 59/140 (42%), Gaps = 20/140 (14%)

Query: 95  DGVRQKIFQVAQELSGEDMHQFHRAITTGLQEYVE------AVSFQHFIKTRSLISMDEI 148
           D +RQKI Q+ QELS          ++   QEY+E      + +   F    S ++ D I
Sbjct: 123 DEMRQKIRQLTQELS----------VSHAQQEYLENHIQTQSSALDRFNAMNSALASDSI 172

Query: 149 --NKQLIFTTEDNGKENKTPSSDAQDKQFGTWRLRVTPVDYLLGVADLTGELMRMCINSV 206
              K L+  T +N        +  Q  +    +LR       L VA +  +L++M + S 
Sbjct: 173 GLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLR--EKQRQLEVAQVENQLLKMKVESS 230

Query: 207 GNGDIDTPFEVSQFLRQVYD 226
              + +   E+++ L   Y+
Sbjct: 231 QEANAEVMREMTKKLYSQYE 250


>gi|27436951 lamin B2 [Homo sapiens]
          Length = 600

 Score = 28.1 bits (61), Expect = 9.4
 Identities = 28/107 (26%), Positives = 49/107 (45%), Gaps = 10/107 (9%)

Query: 10  FRKRKHDNFPHNQRREGK----DVNSSSPVMLAFKSFQ--QELDARHDKYERLVKLSRDI 63
           FRK   +      RR  +    +V+SS      FK  Q  +EL ++HD+  RL KL  + 
Sbjct: 201 FRKSVFEEEVRETRRRHERRLVEVDSSRQQEYDFKMAQALEELRSQHDEQVRLYKLELEQ 260

Query: 64  TVESKRTIFLLHRITSAPDMEDILTESEIKLDGVRQKIFQVAQELSG 110
           T ++K     L    S+   +   + +  +L   R ++  ++ +LSG
Sbjct: 261 TYQAKLDSAKL----SSDQNDKAASAAREELKEARMRLESLSYQLSG 303


>gi|7710129 LIM domain only 6 [Homo sapiens]
          Length = 615

 Score = 28.1 bits (61), Expect = 9.4
 Identities = 25/106 (23%), Positives = 41/106 (38%), Gaps = 9/106 (8%)

Query: 108 LSGEDMHQFHRAITTGLQEYVEAVSFQHFIKT--RSLISMDEINKQLIFTTEDNGKENKT 165
           L  E ++QF   +      YV +   ++ IK     L   D   +      E+  KE + 
Sbjct: 100 LKPEQVYQFFSCLPEDKVPYVNSPGEKYRIKQLLHQLPPHDSEAQYCTALEEEEKKELRA 159

Query: 166 PSSDAQDKQFGTWRLRVTPVDYLLGVADLTGELMRMCINSVGNGDI 211
            S   + +  G   +R+ PV        +TG +   C   +G GDI
Sbjct: 160 FSQQRKRENLGRGIVRIFPVT-------ITGAICEECGKQIGGGDI 198


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,836,197
Number of Sequences: 37866
Number of extensions: 388583
Number of successful extensions: 1013
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 1007
Number of HSP's gapped (non-prelim): 17
length of query: 290
length of database: 18,247,518
effective HSP length: 101
effective length of query: 189
effective length of database: 14,423,052
effective search space: 2725956828
effective search space used: 2725956828
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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