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Search of human proteins with 5174697
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5174697 alpha2,3-sialyltransferase VI [Homo sapiens]
(331 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5174697 alpha2,3-sialyltransferase VI [Homo sapiens] 688 0.0
gi|5454058 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [H... 202 3e-52
gi|28373082 sialyltransferase 6 isoform g [Homo sapiens] 193 2e-49
gi|28373086 sialyltransferase 6 isoform i [Homo sapiens] 192 5e-49
gi|28373078 sialyltransferase 6 isoform f [Homo sapiens] 192 5e-49
gi|28373070 sialyltransferase 6 isoform b [Homo sapiens] 192 5e-49
gi|28373068 sialyltransferase 6 isoform a [Homo sapiens] 192 5e-49
gi|5454060 sialyltransferase 6 isoform j [Homo sapiens] 192 5e-49
gi|109633046 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 ... 168 7e-42
gi|109633044 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 ... 168 7e-42
gi|28373074 sialyltransferase 6 isoform d [Homo sapiens] 113 2e-25
gi|27765096 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [... 96 4e-20
gi|4506951 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [H... 96 4e-20
gi|5902082 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [H... 89 5e-18
gi|215272345 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2... 82 7e-16
gi|26190610 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 ... 82 7e-16
gi|21264332 sialyltransferase 7A [Homo sapiens] 74 2e-13
gi|215272347 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2... 66 5e-11
gi|4506949 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 i... 65 1e-10
gi|27765091 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 ... 65 1e-10
gi|5174677 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransf... 64 2e-10
gi|192448440 sialyltransferase 7B [Homo sapiens] 63 3e-10
gi|28373101 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltrans... 61 2e-09
gi|5031999 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransf... 59 5e-09
gi|110815855 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltran... 59 6e-09
gi|28373092 sialyltransferase 7D isoform a [Homo sapiens] 54 1e-07
gi|229892273 sialyltransferase 7C isoform 1 [Homo sapiens] 54 2e-07
gi|229892275 sialyltransferase 7C isoform 2 [Homo sapiens] 52 7e-07
gi|21361444 sialytransferase 7F [Homo sapiens] 49 5e-06
gi|13569938 sialyltransferase 7E [Homo sapiens] 49 6e-06
>gi|5174697 alpha2,3-sialyltransferase VI [Homo sapiens]
Length = 331
Score = 688 bits (1775), Expect = 0.0
Identities = 331/331 (100%), Positives = 331/331 (100%)
Query: 1 MRGYLVAIFLSAVFLYYVLHCILWGTNVYWVAPVEMKRRNKIQPCLSKPAFASLLRFHQF 60
MRGYLVAIFLSAVFLYYVLHCILWGTNVYWVAPVEMKRRNKIQPCLSKPAFASLLRFHQF
Sbjct: 1 MRGYLVAIFLSAVFLYYVLHCILWGTNVYWVAPVEMKRRNKIQPCLSKPAFASLLRFHQF 60
Query: 61 HPFLCAADFRKIASLYGSDKFDLPYGMRTSAEYFRLALSKLQSCDLFDEFDNIPCKKCVV 120
HPFLCAADFRKIASLYGSDKFDLPYGMRTSAEYFRLALSKLQSCDLFDEFDNIPCKKCVV
Sbjct: 61 HPFLCAADFRKIASLYGSDKFDLPYGMRTSAEYFRLALSKLQSCDLFDEFDNIPCKKCVV 120
Query: 121 VGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRTTFRLFYPESVFSDPIHNDP 180
VGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRTTFRLFYPESVFSDPIHNDP
Sbjct: 121 VGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRTTFRLFYPESVFSDPIHNDP 180
Query: 181 NTTVILTAFKPHDLRWLLELLMGDKINTNGFWKKPALNLIYKPYQIRILDPFIIRTAAYE 240
NTTVILTAFKPHDLRWLLELLMGDKINTNGFWKKPALNLIYKPYQIRILDPFIIRTAAYE
Sbjct: 181 NTTVILTAFKPHDLRWLLELLMGDKINTNGFWKKPALNLIYKPYQIRILDPFIIRTAAYE 240
Query: 241 LLHFPKVFPKNQKPKHPTTGIIAITLAFYICHEVHLAGFKYNFSDLKSPLHYYGNATMSL 300
LLHFPKVFPKNQKPKHPTTGIIAITLAFYICHEVHLAGFKYNFSDLKSPLHYYGNATMSL
Sbjct: 241 LLHFPKVFPKNQKPKHPTTGIIAITLAFYICHEVHLAGFKYNFSDLKSPLHYYGNATMSL 300
Query: 301 MNKNAYHNVTAEQLFLKDIIEKNLVINLTQD 331
MNKNAYHNVTAEQLFLKDIIEKNLVINLTQD
Sbjct: 301 MNKNAYHNVTAEQLFLKDIIEKNLVINLTQD 331
>gi|5454058 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [Homo
sapiens]
Length = 329
Score = 202 bits (514), Expect = 3e-52
Identities = 109/251 (43%), Positives = 156/251 (62%), Gaps = 5/251 (1%)
Query: 81 FDLPYGMRTSAEYFRLALSKLQSCDLFDEFDNIPCKKCVVVGNGGVLKNKTLGEKIDSYD 140
++LPYG + S + L+ + S + ++ C++CVVVGNG L+N +LG+ I+ YD
Sbjct: 80 YELPYGTKGSEDLLLRVLA-ITSSSIPKNIQSLRCRRCVVVGNGHRLRNSSLGDAINKYD 138
Query: 141 VIIRMNNGPVLGHEEEVGRRTTFRLFYPESVFSDP-IHNDPNTTVILTAFKPHDLRWLLE 199
V+IR+NN PV G+E +VG +TT RLFYPES DP + N+P+T ++L AFK D W+
Sbjct: 139 VVIRLNNAPVAGYEGDVGSKTTMRLFYPESAHFDPKVENNPDTLLVLVAFKAMDFHWIET 198
Query: 200 LLMGDKINTNGFWKKPALNLIYKPYQIRILDPFIIRTAAYELLHFPKVFPKNQKPKHPTT 259
+L K GFWK+P L P QIRIL+PF + AA +LL P P+ K K PTT
Sbjct: 199 ILSDKKRVRKGFWKQPPLIWDVNPKQIRILNPFFMEIAADKLLSLPMQQPRKIKQK-PTT 257
Query: 260 GIIAITLAFYICHEVHLAGFKY-NFSDLKSPLHYYGNATMSLMNKNAYHNVTAEQLFLKD 318
G++AITLA ++C VH+AGF Y + + K +HYY T+ M + HNV+ E L +K
Sbjct: 258 GLLAITLALHLCDLVHIAGFGYPDAYNKKQTIHYYEQITLKSM-AGSGHNVSQEALAIKR 316
Query: 319 IIEKNLVINLT 329
++E + NLT
Sbjct: 317 MLEMGAIKNLT 327
>gi|28373082 sialyltransferase 6 isoform g [Homo sapiens]
Length = 359
Score = 193 bits (491), Expect = 2e-49
Identities = 111/346 (32%), Positives = 186/346 (53%), Gaps = 25/346 (7%)
Query: 6 VAIFLSAVFLYYV---LHCILWGT-----------NVYWVAPVEMKRRN-KIQPCLSKPA 50
+ +FL FLYY LH + W N+ P E+ + KP
Sbjct: 14 LCLFLVLGFLYYSAWKLHLLQWEEDSKYDRLGFLLNLDSKLPAELATKYANFSEGACKPG 73
Query: 51 FASLL------RFHQFHPFLCAADFRKIASLYGSDKFDLPYGMRTSAEYFRLALSKLQSC 104
+AS L RF + P FRK A + +F P+G++ + LS +
Sbjct: 74 YASALMTAIFPRFSKPAPMFLDDSFRKWARIR---EFVPPFGIKGQDNLIKAILSVTKEY 130
Query: 105 DLFDEFDNIPCKKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRTTFR 164
L D++ C++C++VGNGGVL NK+LG +ID YD+++R+N+ PV G E++VG +TT R
Sbjct: 131 RLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLR 190
Query: 165 LFYPESVFSDPIHNDPNTTVILTAFKPHDLRWLLELLMGDKIN-TNGFWKKPALNLIYKP 223
+ YPE P + ++ +L FK D +WL ++ ++++ ++GFWK A + +P
Sbjct: 191 ITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEP 250
Query: 224 YQIRILDPFIIRTAAYELLHFPKVFPKNQKPKHPTTGIIAITLAFYICHEVHLAGFKYNF 283
+IRIL+P+ I+ AA+ L+ P + PT G +A+T+A + C EV +AGF Y+
Sbjct: 251 PEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDM 310
Query: 284 SDLKSPLHYYGNATMSLMNKNAYHNVTAEQLFLKDIIEKNLVINLT 329
S +PLHYY M+ + ++ HN+ E+ FL+ +++ ++ +L+
Sbjct: 311 STPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLS 356
>gi|28373086 sialyltransferase 6 isoform i [Homo sapiens]
Length = 413
Score = 192 bits (487), Expect = 5e-49
Identities = 99/289 (34%), Positives = 168/289 (58%), Gaps = 10/289 (3%)
Query: 48 KPAFASLL------RFHQFHPFLCAADFRKIASLYGSDKFDLPYGMRTSAEYFRLALSKL 101
KP +AS L RF + P FRK A + +F P+G++ + LS
Sbjct: 125 KPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIR---EFVPPFGIKGQDNLIKAILSVT 181
Query: 102 QSCDLFDEFDNIPCKKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRT 161
+ L D++ C++C++VGNGGVL NK+LG +ID YD+++R+N+ PV G E++VG +T
Sbjct: 182 KEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKT 241
Query: 162 TFRLFYPESVFSDPIHNDPNTTVILTAFKPHDLRWLLELLMGDKIN-TNGFWKKPALNLI 220
T R+ YPE P + ++ +L FK D +WL ++ ++++ ++GFWK A +
Sbjct: 242 TLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVP 301
Query: 221 YKPYQIRILDPFIIRTAAYELLHFPKVFPKNQKPKHPTTGIIAITLAFYICHEVHLAGFK 280
+P +IRIL+P+ I+ AA+ L+ P + PT G +A+T+A + C EV +AGF
Sbjct: 302 KEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFG 361
Query: 281 YNFSDLKSPLHYYGNATMSLMNKNAYHNVTAEQLFLKDIIEKNLVINLT 329
Y+ S +PLHYY M+ + ++ HN+ E+ FL+ +++ ++ +L+
Sbjct: 362 YDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLS 410
>gi|28373078 sialyltransferase 6 isoform f [Homo sapiens]
Length = 429
Score = 192 bits (487), Expect = 5e-49
Identities = 99/289 (34%), Positives = 168/289 (58%), Gaps = 10/289 (3%)
Query: 48 KPAFASLL------RFHQFHPFLCAADFRKIASLYGSDKFDLPYGMRTSAEYFRLALSKL 101
KP +AS L RF + P FRK A + +F P+G++ + LS
Sbjct: 141 KPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIR---EFVPPFGIKGQDNLIKAILSVT 197
Query: 102 QSCDLFDEFDNIPCKKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRT 161
+ L D++ C++C++VGNGGVL NK+LG +ID YD+++R+N+ PV G E++VG +T
Sbjct: 198 KEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKT 257
Query: 162 TFRLFYPESVFSDPIHNDPNTTVILTAFKPHDLRWLLELLMGDKIN-TNGFWKKPALNLI 220
T R+ YPE P + ++ +L FK D +WL ++ ++++ ++GFWK A +
Sbjct: 258 TLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVP 317
Query: 221 YKPYQIRILDPFIIRTAAYELLHFPKVFPKNQKPKHPTTGIIAITLAFYICHEVHLAGFK 280
+P +IRIL+P+ I+ AA+ L+ P + PT G +A+T+A + C EV +AGF
Sbjct: 318 KEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFG 377
Query: 281 YNFSDLKSPLHYYGNATMSLMNKNAYHNVTAEQLFLKDIIEKNLVINLT 329
Y+ S +PLHYY M+ + ++ HN+ E+ FL+ +++ ++ +L+
Sbjct: 378 YDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLS 426
>gi|28373070 sialyltransferase 6 isoform b [Homo sapiens]
Length = 390
Score = 192 bits (487), Expect = 5e-49
Identities = 99/289 (34%), Positives = 168/289 (58%), Gaps = 10/289 (3%)
Query: 48 KPAFASLL------RFHQFHPFLCAADFRKIASLYGSDKFDLPYGMRTSAEYFRLALSKL 101
KP +AS L RF + P FRK A + +F P+G++ + LS
Sbjct: 102 KPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIR---EFVPPFGIKGQDNLIKAILSVT 158
Query: 102 QSCDLFDEFDNIPCKKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRT 161
+ L D++ C++C++VGNGGVL NK+LG +ID YD+++R+N+ PV G E++VG +T
Sbjct: 159 KEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKT 218
Query: 162 TFRLFYPESVFSDPIHNDPNTTVILTAFKPHDLRWLLELLMGDKIN-TNGFWKKPALNLI 220
T R+ YPE P + ++ +L FK D +WL ++ ++++ ++GFWK A +
Sbjct: 219 TLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVP 278
Query: 221 YKPYQIRILDPFIIRTAAYELLHFPKVFPKNQKPKHPTTGIIAITLAFYICHEVHLAGFK 280
+P +IRIL+P+ I+ AA+ L+ P + PT G +A+T+A + C EV +AGF
Sbjct: 279 KEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFG 338
Query: 281 YNFSDLKSPLHYYGNATMSLMNKNAYHNVTAEQLFLKDIIEKNLVINLT 329
Y+ S +PLHYY M+ + ++ HN+ E+ FL+ +++ ++ +L+
Sbjct: 339 YDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLS 387
>gi|28373068 sialyltransferase 6 isoform a [Homo sapiens]
Length = 444
Score = 192 bits (487), Expect = 5e-49
Identities = 99/289 (34%), Positives = 168/289 (58%), Gaps = 10/289 (3%)
Query: 48 KPAFASLL------RFHQFHPFLCAADFRKIASLYGSDKFDLPYGMRTSAEYFRLALSKL 101
KP +AS L RF + P FRK A + +F P+G++ + LS
Sbjct: 156 KPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIR---EFVPPFGIKGQDNLIKAILSVT 212
Query: 102 QSCDLFDEFDNIPCKKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRT 161
+ L D++ C++C++VGNGGVL NK+LG +ID YD+++R+N+ PV G E++VG +T
Sbjct: 213 KEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKT 272
Query: 162 TFRLFYPESVFSDPIHNDPNTTVILTAFKPHDLRWLLELLMGDKIN-TNGFWKKPALNLI 220
T R+ YPE P + ++ +L FK D +WL ++ ++++ ++GFWK A +
Sbjct: 273 TLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVP 332
Query: 221 YKPYQIRILDPFIIRTAAYELLHFPKVFPKNQKPKHPTTGIIAITLAFYICHEVHLAGFK 280
+P +IRIL+P+ I+ AA+ L+ P + PT G +A+T+A + C EV +AGF
Sbjct: 333 KEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFG 392
Query: 281 YNFSDLKSPLHYYGNATMSLMNKNAYHNVTAEQLFLKDIIEKNLVINLT 329
Y+ S +PLHYY M+ + ++ HN+ E+ FL+ +++ ++ +L+
Sbjct: 393 YDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLS 441
>gi|5454060 sialyltransferase 6 isoform j [Homo sapiens]
Length = 375
Score = 192 bits (487), Expect = 5e-49
Identities = 99/289 (34%), Positives = 168/289 (58%), Gaps = 10/289 (3%)
Query: 48 KPAFASLL------RFHQFHPFLCAADFRKIASLYGSDKFDLPYGMRTSAEYFRLALSKL 101
KP +AS L RF + P FRK A + +F P+G++ + LS
Sbjct: 87 KPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIR---EFVPPFGIKGQDNLIKAILSVT 143
Query: 102 QSCDLFDEFDNIPCKKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRT 161
+ L D++ C++C++VGNGGVL NK+LG +ID YD+++R+N+ PV G E++VG +T
Sbjct: 144 KEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKT 203
Query: 162 TFRLFYPESVFSDPIHNDPNTTVILTAFKPHDLRWLLELLMGDKIN-TNGFWKKPALNLI 220
T R+ YPE P + ++ +L FK D +WL ++ ++++ ++GFWK A +
Sbjct: 204 TLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVP 263
Query: 221 YKPYQIRILDPFIIRTAAYELLHFPKVFPKNQKPKHPTTGIIAITLAFYICHEVHLAGFK 280
+P +IRIL+P+ I+ AA+ L+ P + PT G +A+T+A + C EV +AGF
Sbjct: 264 KEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFG 323
Query: 281 YNFSDLKSPLHYYGNATMSLMNKNAYHNVTAEQLFLKDIIEKNLVINLT 329
Y+ S +PLHYY M+ + ++ HN+ E+ FL+ +++ ++ +L+
Sbjct: 324 YDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLS 372
>gi|109633046 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
isoform 2 [Homo sapiens]
Length = 395
Score = 168 bits (425), Expect = 7e-42
Identities = 102/315 (32%), Positives = 164/315 (52%), Gaps = 13/315 (4%)
Query: 28 VYWVAPVEMKRRNKI-QPCLSK---PAFA----SLLRFHQFHPFLCAADFRKIASLYGSD 79
+++V P +KR K Q L K P FA +LL H++ L +
Sbjct: 74 MHYVDPDHVKRAQKYAQQVLQKECRPKFAKTSMALLFEHRYSVDLLPFVQKAPKDSEAES 133
Query: 80 KFDLPYGMRTSAEYFRLALSKLQSCDLFDEFDNIPCKKCVVVGNGGVLKNKTLGEKIDSY 139
K+D P+G R + + L L DL + C++CVV+G+GG+L LG ++ +
Sbjct: 134 KYDPPFGFRKFSSKVQTLLELLPEHDLPEHLKAKTCRRCVVIGSGGILHGLELGHTLNQF 193
Query: 140 DVIIRMNNGPVLGHEEEVGRRTTFRLFYPESVFSDPIHNDPNTTVILTAFKPHDLRWLLE 199
DV+IR+N+ PV G+ E VG +TT R+ YPE + N + FK D WL
Sbjct: 194 DVVIRLNSAPVEGYSEHVGNKTTIRMTYPEGAPLSDLEYYSNDLFVAVLFKSVDFNWLQA 253
Query: 200 LLMGDKIN---TNGFWKKPALNLIYKPYQIRILDPFIIRTAAYELLHF--PKVFPKNQKP 254
++ + + FWK+ A + +P RIL+P II+ A+++L + P+ +
Sbjct: 254 MVKKETLPFWVRLFFWKQVAEKIPLQPKHFRILNPVIIKETAFDILQYSEPQSRFWGRDK 313
Query: 255 KHPTTGIIAITLAFYICHEVHLAGFKYNFSDLKSPLHYYGNATMSLMNKNAYHNVTAEQL 314
PT G+IA+ LA ++C EV LAGF Y+ + ++PLHY+ + M+ MN HNVT E
Sbjct: 314 NVPTIGVIAVVLATHLCDEVSLAGFGYDLNQPRTPLHYFDSQCMAAMNFQTMHNVTTETK 373
Query: 315 FLKDIIEKNLVINLT 329
FL ++++ +V +L+
Sbjct: 374 FLLKLVKEGVVKDLS 388
>gi|109633044 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
isoform 1 [Homo sapiens]
Length = 418
Score = 168 bits (425), Expect = 7e-42
Identities = 102/315 (32%), Positives = 164/315 (52%), Gaps = 13/315 (4%)
Query: 28 VYWVAPVEMKRRNKI-QPCLSK---PAFA----SLLRFHQFHPFLCAADFRKIASLYGSD 79
+++V P +KR K Q L K P FA +LL H++ L +
Sbjct: 97 MHYVDPDHVKRAQKYAQQVLQKECRPKFAKTSMALLFEHRYSVDLLPFVQKAPKDSEAES 156
Query: 80 KFDLPYGMRTSAEYFRLALSKLQSCDLFDEFDNIPCKKCVVVGNGGVLKNKTLGEKIDSY 139
K+D P+G R + + L L DL + C++CVV+G+GG+L LG ++ +
Sbjct: 157 KYDPPFGFRKFSSKVQTLLELLPEHDLPEHLKAKTCRRCVVIGSGGILHGLELGHTLNQF 216
Query: 140 DVIIRMNNGPVLGHEEEVGRRTTFRLFYPESVFSDPIHNDPNTTVILTAFKPHDLRWLLE 199
DV+IR+N+ PV G+ E VG +TT R+ YPE + N + FK D WL
Sbjct: 217 DVVIRLNSAPVEGYSEHVGNKTTIRMTYPEGAPLSDLEYYSNDLFVAVLFKSVDFNWLQA 276
Query: 200 LLMGDKIN---TNGFWKKPALNLIYKPYQIRILDPFIIRTAAYELLHF--PKVFPKNQKP 254
++ + + FWK+ A + +P RIL+P II+ A+++L + P+ +
Sbjct: 277 MVKKETLPFWVRLFFWKQVAEKIPLQPKHFRILNPVIIKETAFDILQYSEPQSRFWGRDK 336
Query: 255 KHPTTGIIAITLAFYICHEVHLAGFKYNFSDLKSPLHYYGNATMSLMNKNAYHNVTAEQL 314
PT G+IA+ LA ++C EV LAGF Y+ + ++PLHY+ + M+ MN HNVT E
Sbjct: 337 NVPTIGVIAVVLATHLCDEVSLAGFGYDLNQPRTPLHYFDSQCMAAMNFQTMHNVTTETK 396
Query: 315 FLKDIIEKNLVINLT 329
FL ++++ +V +L+
Sbjct: 397 FLLKLVKEGVVKDLS 411
>gi|28373074 sialyltransferase 6 isoform d [Homo sapiens]
Length = 277
Score = 113 bits (283), Expect = 2e-25
Identities = 57/166 (34%), Positives = 94/166 (56%), Gaps = 9/166 (5%)
Query: 48 KPAFASLL------RFHQFHPFLCAADFRKIASLYGSDKFDLPYGMRTSAEYFRLALSKL 101
KP +AS L RF + P FRK A + +F P+G++ + LS
Sbjct: 87 KPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIR---EFVPPFGIKGQDNLIKAILSVT 143
Query: 102 QSCDLFDEFDNIPCKKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRT 161
+ L D++ C++C++VGNGGVL NK+LG +ID YD+++R+N+ PV G E++VG +T
Sbjct: 144 KEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKT 203
Query: 162 TFRLFYPESVFSDPIHNDPNTTVILTAFKPHDLRWLLELLMGDKIN 207
T R+ YPE P + ++ +L FK D +WL ++ ++++
Sbjct: 204 TLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVS 249
>gi|27765096 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
[Homo sapiens]
Length = 340
Score = 95.9 bits (237), Expect = 4e-20
Identities = 69/226 (30%), Positives = 107/226 (47%), Gaps = 22/226 (9%)
Query: 89 TSAEYFRLALSKLQSCDLFDEFDNIPCKKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNG 148
T E FR+ + D E ++ C++C VVGN G L+ + G +IDS+D ++RMN
Sbjct: 116 TIKELFRVVPGNV---DPMLEKRSVGCRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKA 172
Query: 149 PVLGHEEEVGRRTTFRLFYPESVFSDPIHNDPNTTVILTAFKPHDLRWLLELLMGDKINT 208
P G E +VG +TT L YPES N ++IL FK DL W++ + I +
Sbjct: 173 PTAGFEADVGTKTTHHLVYPESF----RELGDNVSMILVPFKTIDLEWVVSAITTGTI-S 227
Query: 209 NGFWKKPALNLIYKPYQIRILDPFIIRTAAYELLHFPKVFPKNQKPKHPTTGIIAITLAF 268
+ + PA + K +I I P I+ L ++P+TGI+++ +
Sbjct: 228 HTYIPVPA-KIRVKQDKILIYHPAFIKYVFDNWL--------QGHGRYPSTGILSVIFSM 278
Query: 269 YICHEVHLAGFKYNFSDLKSPLHYY--GNATMSLMNKNAYHNVTAE 312
++C EV L GF +D K H+Y N + K H+ E
Sbjct: 279 HVCDEVDLYGFG---ADSKGNWHHYWENNPSAGAFRKTGVHDADFE 321
>gi|4506951 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [Homo
sapiens]
Length = 340
Score = 95.9 bits (237), Expect = 4e-20
Identities = 69/226 (30%), Positives = 107/226 (47%), Gaps = 22/226 (9%)
Query: 89 TSAEYFRLALSKLQSCDLFDEFDNIPCKKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNG 148
T E FR+ + D E ++ C++C VVGN G L+ + G +IDS+D ++RMN
Sbjct: 116 TIKELFRVVPGNV---DPMLEKRSVGCRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKA 172
Query: 149 PVLGHEEEVGRRTTFRLFYPESVFSDPIHNDPNTTVILTAFKPHDLRWLLELLMGDKINT 208
P G E +VG +TT L YPES N ++IL FK DL W++ + I +
Sbjct: 173 PTAGFEADVGTKTTHHLVYPESF----RELGDNVSMILVPFKTIDLEWVVSAITTGTI-S 227
Query: 209 NGFWKKPALNLIYKPYQIRILDPFIIRTAAYELLHFPKVFPKNQKPKHPTTGIIAITLAF 268
+ + PA + K +I I P I+ L ++P+TGI+++ +
Sbjct: 228 HTYIPVPA-KIRVKQDKILIYHPAFIKYVFDNWL--------QGHGRYPSTGILSVIFSM 278
Query: 269 YICHEVHLAGFKYNFSDLKSPLHYY--GNATMSLMNKNAYHNVTAE 312
++C EV L GF +D K H+Y N + K H+ E
Sbjct: 279 HVCDEVDLYGFG---ADSKGNWHHYWENNPSAGAFRKTGVHDADFE 321
>gi|5902082 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [Homo
sapiens]
Length = 350
Score = 89.0 bits (219), Expect = 5e-18
Identities = 58/201 (28%), Positives = 97/201 (48%), Gaps = 21/201 (10%)
Query: 115 CKKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRTTFRLFYPESVFSD 174
C++C VVGN G L+ G+ +D ++ I+RMN P +G E++VG RTT YPES +
Sbjct: 149 CRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAPTVGFEQDVGSRTTHHFMYPESAKNL 208
Query: 175 PIHNDPNTTVILTAFKPHDLRWLLELLMGDKINTNGFWKKPALNLI-YKPYQIRILDPFI 233
P N + +L FK DL W+ L +I F P + + +++I +P
Sbjct: 209 P----ANVSFVLVPFKVLDLLWIASALSTGQIR---FTYAPVKSFLRVDKEKVQIYNP-- 259
Query: 234 IRTAAYELLHFPKVFPKNQKPKHPTTGIIAITLAFYICHEVHLAGFKYNFSDLKSPLHYY 293
A ++ +H ++P+TG++ + A ++C EV++ GF +D + H+Y
Sbjct: 260 ---AFFKYIHDRWT---EHHGRYPSTGMLVLFFALHVCDEVNVYGFG---ADSRGNWHHY 310
Query: 294 --GNATMSLMNKNAYHNVTAE 312
N K H+ E
Sbjct: 311 WENNRYAGEFRKTGVHDADFE 331
>gi|215272345 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
isoform a [Homo sapiens]
Length = 529
Score = 82.0 bits (201), Expect = 7e-16
Identities = 64/218 (29%), Positives = 109/218 (50%), Gaps = 34/218 (15%)
Query: 116 KKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRTTFRLFYPESVFSDP 175
+ C VV + G + N +LGE+IDS+D ++R N+ P G+E++VG +TT R+ + + ++P
Sbjct: 294 RSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQ-ILTNP 352
Query: 176 IHNDPNTT----VILTAFKPHDLRWLLELLMGDKINTNGFWKKPALNLIYKPYQIRILDP 231
H+ +++ VIL A+ P N N ++KKP NL Q R +P
Sbjct: 353 SHHFIDSSLYKDVILVAWDPAPY----------SANLNLWYKKPDYNLFTPYIQHRQRNP 402
Query: 232 FIIRTAAYELLHFPK-------VFPKNQK----PKHPTTGIIAITLAFYICHEVHLAGFK 280
+ +LH PK + +N K P P++G I I + +C EVH+ ++
Sbjct: 403 ----NQPFYILH-PKFIWQLWDIIQENTKEKIQPNPPSSGFIGILIMMSMCREVHV--YE 455
Query: 281 YNFSDLKSPL-HYYGNATMSLMNKNAYHNVTAEQLFLK 317
Y S ++ L HY+ + AYH + E+L ++
Sbjct: 456 YIPSVRQTELCHYHELYYDAACTLGAYHPLLYEKLLVQ 493
>gi|26190610 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
isoform a [Homo sapiens]
Length = 529
Score = 82.0 bits (201), Expect = 7e-16
Identities = 64/218 (29%), Positives = 109/218 (50%), Gaps = 34/218 (15%)
Query: 116 KKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRTTFRLFYPESVFSDP 175
+ C VV + G + N +LGE+IDS+D ++R N+ P G+E++VG +TT R+ + + ++P
Sbjct: 294 RSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQ-ILTNP 352
Query: 176 IHNDPNTT----VILTAFKPHDLRWLLELLMGDKINTNGFWKKPALNLIYKPYQIRILDP 231
H+ +++ VIL A+ P N N ++KKP NL Q R +P
Sbjct: 353 SHHFIDSSLYKDVILVAWDPAPY----------SANLNLWYKKPDYNLFTPYIQHRQRNP 402
Query: 232 FIIRTAAYELLHFPK-------VFPKNQK----PKHPTTGIIAITLAFYICHEVHLAGFK 280
+ +LH PK + +N K P P++G I I + +C EVH+ ++
Sbjct: 403 ----NQPFYILH-PKFIWQLWDIIQENTKEKIQPNPPSSGFIGILIMMSMCREVHV--YE 455
Query: 281 YNFSDLKSPL-HYYGNATMSLMNKNAYHNVTAEQLFLK 317
Y S ++ L HY+ + AYH + E+L ++
Sbjct: 456 YIPSVRQTELCHYHELYYDAACTLGAYHPLLYEKLLVQ 493
>gi|21264332 sialyltransferase 7A [Homo sapiens]
Length = 600
Score = 73.9 bits (180), Expect = 2e-13
Identities = 58/211 (27%), Positives = 91/211 (43%), Gaps = 28/211 (13%)
Query: 112 NIPCKKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRTTFRLFYPESV 171
++ C C VVGNGG+L N +G++IDS+D + R++ + G+E++VG RT+F F S+
Sbjct: 359 SLRCITCAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSL 418
Query: 172 FSD------------PIHNDPNTTVILTAFKPHDLRWLLELLMGDKI-NTNGFW----KK 214
P+ D L + D WL LLM + + N FW +
Sbjct: 419 TQSLLILGNRGFKNVPLGKDVRYLHFLEGTR--DYEWLEALLMNQTVMSKNLFWFRHRPQ 476
Query: 215 PALNLIYKPYQIRILDPFIIRTAAYELLHFPKVFPKNQKPKHPTTGIIAITLAFYICHEV 274
A + +L P +R L + + + PTTG + + A +C +V
Sbjct: 477 EAFREALHMDRYLLLHPDFLRYMKNRFLRSKTLDGAHWRIYRPTTGALLLLTALQLCDQV 536
Query: 275 HLAGF----KYNFSDLKSPLHYYGNATMSLM 301
GF FSD HYY + L+
Sbjct: 537 SAYGFITEGHERFSD-----HYYDTSWKRLI 562
>gi|215272347 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
isoform b [Homo sapiens]
Length = 466
Score = 65.9 bits (159), Expect = 5e-11
Identities = 49/162 (30%), Positives = 81/162 (50%), Gaps = 31/162 (19%)
Query: 116 KKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRTTFRLFYPESVFSDP 175
+ C VV + G + N +LGE+IDS+D ++R N+ P G+E++VG +TT R+ + + ++P
Sbjct: 294 RSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQ-ILTNP 352
Query: 176 IHNDPNTT----VILTAFKPHDLRWLLELLMGDKINTNGFWKKPALNLIYKPYQIRILDP 231
H+ +++ VIL A+ P N N ++KKP NL Q R +P
Sbjct: 353 SHHFIDSSLYKDVILVAWDPAPY----------SANLNLWYKKPDYNLFTPYIQHRQRNP 402
Query: 232 FIIRTAAYELLHFPK-------VFPKNQK----PKHPTTGII 262
+ +LH PK + +N K P P++G I
Sbjct: 403 ----NQPFYILH-PKFIWQLWDIIQENTKEKIQPNPPSSGFI 439
>gi|4506949 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
isoform a [Homo sapiens]
Length = 406
Score = 64.7 bits (156), Expect = 1e-10
Identities = 59/231 (25%), Positives = 103/231 (44%), Gaps = 40/231 (17%)
Query: 114 PCKKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRTTFRLFYPESV-- 171
P +C VV + G LK+ LG +ID +D ++R N P +++VG +TT RL + V
Sbjct: 180 PWGRCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAPTANFQQDVGTKTTIRLMNSQLVTT 239
Query: 172 ----FSDPIHNDPNTTVILTAFKPHDL-RWLLELLMGDKINTNGFWKKPALNLI--YKPY 224
D ++N+ V + D+ +W ++ P N YK Y
Sbjct: 240 EKRFLKDSLYNEGILIVWDPSVYHSDIPKW---------------YQNPDYNFFNNYKTY 284
Query: 225 -QIRILDPFII--RTAAYELLH-FPKVFPKNQKPKHPTTGIIAITLAFYICHEVHLAGFK 280
++ PF I +EL ++ P+ +P P++G++ I + +C +V + ++
Sbjct: 285 RKLHPNQPFYILKPQMPWELWDILQEISPEEIQPNPPSSGMLGIIIMMTLCDQVDI--YE 342
Query: 281 YNFSDLKSPL-HYYGNATMSLMNKNAYHNVTAEQLFLKDIIEKNLVINLTQ 330
+ S K+ + +YY S AYH + + EKNLV +L Q
Sbjct: 343 FLPSKRKTDVCYYYQKFFDSACTMGAYHPL---------LYEKNLVKHLNQ 384
>gi|27765091 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
isoform a [Homo sapiens]
Length = 406
Score = 64.7 bits (156), Expect = 1e-10
Identities = 59/231 (25%), Positives = 103/231 (44%), Gaps = 40/231 (17%)
Query: 114 PCKKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRTTFRLFYPESV-- 171
P +C VV + G LK+ LG +ID +D ++R N P +++VG +TT RL + V
Sbjct: 180 PWGRCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAPTANFQQDVGTKTTIRLMNSQLVTT 239
Query: 172 ----FSDPIHNDPNTTVILTAFKPHDL-RWLLELLMGDKINTNGFWKKPALNLI--YKPY 224
D ++N+ V + D+ +W ++ P N YK Y
Sbjct: 240 EKRFLKDSLYNEGILIVWDPSVYHSDIPKW---------------YQNPDYNFFNNYKTY 284
Query: 225 -QIRILDPFII--RTAAYELLH-FPKVFPKNQKPKHPTTGIIAITLAFYICHEVHLAGFK 280
++ PF I +EL ++ P+ +P P++G++ I + +C +V + ++
Sbjct: 285 RKLHPNQPFYILKPQMPWELWDILQEISPEEIQPNPPSSGMLGIIIMMTLCDQVDI--YE 342
Query: 281 YNFSDLKSPL-HYYGNATMSLMNKNAYHNVTAEQLFLKDIIEKNLVINLTQ 330
+ S K+ + +YY S AYH + + EKNLV +L Q
Sbjct: 343 FLPSKRKTDVCYYYQKFFDSACTMGAYHPL---------LYEKNLVKHLNQ 384
>gi|5174677 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 2 [Homo sapiens]
Length = 375
Score = 63.9 bits (154), Expect = 2e-10
Identities = 56/215 (26%), Positives = 94/215 (43%), Gaps = 20/215 (9%)
Query: 118 CVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRTTFRLFYP---ESVFSD 174
C +VGN GVL N G++ID++ +IR N PV + +VG +T P + F D
Sbjct: 157 CAIVGNSGVLLNSGCGQEIDAHSFVIRCNLAPVQEYARDVGLKTDLVTMNPSVIQRAFED 216
Query: 175 PIHNDPNTTVILTAFKPHDLRWLLELLMGDKINTNGFWKKPALNLIYKPYQIRILDPFII 234
++ A L L L G + F + + ++ + +
Sbjct: 217 ----------LVNATWREKLLQRLHSLNGSILWIPAFMARGGKERVEWVNELILKHHVNV 266
Query: 235 RTA--AYELLHFPKVFPKNQKP--KHPTTGIIAITLAFYICHEVHLAGF-KYNFSDLKSP 289
RTA + LLH + + K K PTTG++ TLA C +++L GF + ++P
Sbjct: 267 RTAYPSLRLLHAVRGYWLTNKVHIKRPTTGLLMYTLATRFCKQIYLYGFWPFPLDQNQNP 326
Query: 290 L--HYYGNATMSLMNKNAYHNVTAEQLFLKDIIEK 322
+ HYY + ++ + H + E LK + E+
Sbjct: 327 VKYHYYDSLKYGYTSQASPHTMPLEFKALKSLHEQ 361
>gi|192448440 sialyltransferase 7B [Homo sapiens]
Length = 374
Score = 63.2 bits (152), Expect = 3e-10
Identities = 65/246 (26%), Positives = 102/246 (41%), Gaps = 30/246 (12%)
Query: 84 PYGMR-TSAEYFRLALSKL---QSCDLFDEFDNIP--CKKCVVVGNGGVLKNKTLGEKID 137
PYG R S + LS L +S LF + P C +C VVGNGG+L G ID
Sbjct: 111 PYGWRGLSHQVIASTLSLLNGSESAKLFAPPRDTPPKCIRCAVVGNGGILNGSRQGPNID 170
Query: 138 SYDVIIRMNNGPVLGHEEEVGRRTTFRLFYPESVFSDPIH-------NDPNTTVILTAFK 190
++D + R+N + G E +VG +T+F F ++ + + + P + F
Sbjct: 171 AHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNSLVSYWNLGFTSVPQGQDLQYIFI 230
Query: 191 PHDLR---WLLELLMGDKINTNGFWKKPALNLIYKP----YQIRILDPFIIRTAAYELLH 243
P D+R L ++G + G K + + P + ++L P I L
Sbjct: 231 PSDIRDYVMLRSAILGVPV-PEGLDKGDRPHAYFGPEASASKFKLLHPDFISYLTERFLK 289
Query: 244 FPKVFPKNQKPKHPTTGIIAITLAFYICHEVHLAGF----KYNFSD-----LKSPLHYYG 294
+ P+TG + + A + C +V GF + FSD PL +Y
Sbjct: 290 SKLINTHFGDLYMPSTGALMLLTALHTCDQVSAYGFITSNYWKFSDHYFERKMKPLIFYA 349
Query: 295 NATMSL 300
N +SL
Sbjct: 350 NHDLSL 355
>gi|28373101 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 5 [Homo sapiens]
Length = 376
Score = 60.8 bits (146), Expect = 2e-09
Identities = 56/201 (27%), Positives = 87/201 (43%), Gaps = 43/201 (21%)
Query: 116 KKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVL-GHEEEVGRRTTFRLFYPESVFSD 174
KKC VVGNGG+LKN G +I+S D + R N P+ + +VG +T P S+ ++
Sbjct: 162 KKCAVVGNGGILKNSRCGREINSADFVFRCNLPPISEKYTMDVGVKTDVVTVNP-SIITE 220
Query: 175 PIHN--------------DPNTTVILTAF---KPHDLRWLLELLMGDKINTNGFWKKPAL 217
H N +V+L AF + D+ ++ ++ D ++ P
Sbjct: 221 RFHKLEKWRRPFYRVLQVYENASVLLPAFYNTRNTDVSIRVKYVLDD-------FESPQA 273
Query: 218 NLIYKPYQIRILDPFIIRTAAYELLHFPKVFPKNQKPKHPTTGIIAITLAFYICHEVHLA 277
+ P +++ + Y L + K +TG+I +T A +C EVHL
Sbjct: 274 VYYFHP-------QYLVNVSRYWL-------SLGVRAKRISTGLILVTAALELCEEVHLF 319
Query: 278 G---FKYNFSDLKSPLHYYGN 295
G F N S L HYY N
Sbjct: 320 GFWAFPMNPSGLYITHHYYDN 340
>gi|5031999 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 4 isoform a [Homo sapiens]
Length = 359
Score = 59.3 bits (142), Expect = 5e-09
Identities = 56/220 (25%), Positives = 90/220 (40%), Gaps = 46/220 (20%)
Query: 116 KKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRTTFRLFYPESV---- 171
K C VVGN G+L + G++IDS++ +IR N PV+ +VG ++ F P V
Sbjct: 140 KTCAVVGNSGILLDSECGKEIDSHNFVIRCNLAPVVEFAADVGTKSDFITMNPSVVQRAF 199
Query: 172 -----------FSDPIHNDPNTTVILTAFK----PHDLRWLLELLMGDKINTNGFWKKPA 216
F + ++ + + AF + W+ L++ +K+ + P+
Sbjct: 200 GGFRNESDREKFVHRLSMLNDSVLWIPAFMVKGGEKHVEWVNALILKNKLKVRTAY--PS 257
Query: 217 LNLIYKPYQIRILDPFIIRTAAYELLHFPKVFPKNQKP-KHPTTGIIAITLAFYICHEVH 275
L LI+ Y L N+ P K P+TG++ TLA C E+H
Sbjct: 258 LRLIH-------------AVRGYWL--------TNKVPIKRPSTGLLMYTLATRFCDEIH 296
Query: 276 LAGFKYNFSDLKS---PLHYYGNATMSLMNKNAYHNVTAE 312
L GF DL HYY + + + H + E
Sbjct: 297 LYGFWPFPKDLNGKAVKYHYYDDLKYRYFSNASPHRMPLE 336
>gi|110815855 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 3 [Homo sapiens]
Length = 380
Score = 58.9 bits (141), Expect = 6e-09
Identities = 58/212 (27%), Positives = 88/212 (41%), Gaps = 31/212 (14%)
Query: 118 CVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRTTFRLFYPESVFSDPIH 177
C VVGN G+L G++ID D + R N P + +VGR+T F P S+ +
Sbjct: 162 CAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNP-SILEKYYN 220
Query: 178 NDPNTTVILTAFKPHDLRWLLELLMGDKINTNGFWKKPALNLIYKPYQIRILDPFIIRTA 237
N +LT ++ L+ L G + F+ + + ++D F+
Sbjct: 221 N------LLTIQDRNNFFLSLKKLDGAILWIPAFFFHTSATVTR-----TLVDFFVEHRG 269
Query: 238 AYE---------LLHFPKVFP-KNQKPKHPTTGIIAITLAFYICHEVHLAGF-KYNF--- 283
+ + H + + K+ PK +TGI+ TLA IC E+HL GF + F
Sbjct: 270 QLKVQLAWPGNIMQHVNRYWKNKHLSPKRLSTGILMYTLASAICEEIHLYGFWPFGFDPN 329
Query: 284 --SDLKSPLHYYGNATMSLMNK-NAYHNVTAE 312
DL P HYY K H + AE
Sbjct: 330 TREDL--PYHYYDKKGTKFTTKWQESHQLPAE 359
>gi|28373092 sialyltransferase 7D isoform a [Homo sapiens]
Length = 302
Score = 54.3 bits (129), Expect = 1e-07
Identities = 24/58 (41%), Positives = 35/58 (60%)
Query: 114 PCKKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRTTFRLFYPESV 171
PC+ C VV + G + LG +IDS + + RMN P +G E +VG+R+T R+ SV
Sbjct: 72 PCRSCAVVSSSGQMLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSV 129
>gi|229892273 sialyltransferase 7C isoform 1 [Homo sapiens]
Length = 305
Score = 53.9 bits (128), Expect = 2e-07
Identities = 54/197 (27%), Positives = 78/197 (39%), Gaps = 31/197 (15%)
Query: 113 IPCKKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRTTFRLFYPESV- 171
+ C C +V N G + + +G +ID I RMNN P G+EE+VGR T R+ SV
Sbjct: 75 LDCDLCAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRMTMIRVVSHTSVP 134
Query: 172 ----FSDPIHNDPNTTVILTAFKPHDLRWLLELLMGDKINTNGFWKKPALNLIYKPYQIR 227
D + NTT+ + ++R G+ I N K IY QI
Sbjct: 135 LLLKNPDYFFKEANTTIYVIWGPFRNMR-----KDGNGIVYNMLKKTVG---IYPNAQIY 186
Query: 228 ILDPFIIRTAAYELLHFPKVFPKN------QKPKHPTTGIIAITLAFYICHEVHLAG--- 278
+ T + + VF K Q + +TG LA C+ +H+ G
Sbjct: 187 V-------TTEKRMSYCDGVFKKETGKDRVQSGSYLSTGWFTFLLAMDACYGIHVYGMIN 239
Query: 279 --FKYNFSDLKSPLHYY 293
+ K P HYY
Sbjct: 240 DTYCKTEGYRKVPYHYY 256
>gi|229892275 sialyltransferase 7C isoform 2 [Homo sapiens]
Length = 210
Score = 52.0 bits (123), Expect = 7e-07
Identities = 28/77 (36%), Positives = 39/77 (50%), Gaps = 5/77 (6%)
Query: 113 IPCKKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRTTFRLFYPESV- 171
+ C C +V N G + + +G +ID I RMNN P G+EE+VGR T R+ SV
Sbjct: 75 LDCDLCAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRMTMIRVVSHTSVP 134
Query: 172 ----FSDPIHNDPNTTV 184
D + NTT+
Sbjct: 135 LLLKNPDYFFKEANTTI 151
>gi|21361444 sialytransferase 7F [Homo sapiens]
Length = 333
Score = 49.3 bits (116), Expect = 5e-06
Identities = 22/58 (37%), Positives = 34/58 (58%)
Query: 115 CKKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRTTFRLFYPESVF 172
C +CV+V + L LG +I+ + IRMN+ P G+ +VG +TT+R+ SVF
Sbjct: 105 CHQCVIVSSSSHLLGTKLGPEIERAECTIRMNDAPTTGYSADVGNKTTYRVVAHSSVF 162
>gi|13569938 sialyltransferase 7E [Homo sapiens]
Length = 336
Score = 48.9 bits (115), Expect = 6e-06
Identities = 49/229 (21%), Positives = 98/229 (42%), Gaps = 40/229 (17%)
Query: 115 CKKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRTTFRLFYPESVFSD 174
C+ C +V + G L + G +ID + +IRMN+ P G+ +VG RT+ R+
Sbjct: 93 CRDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRVI-------- 144
Query: 175 PIHNDPNTTVILTAFKPHDLRWLLELLMGDKINTNGFWKKPALNLIYKPYQIRILDPFII 234
++++ HDL + + + + + ++ +Y + +L +
Sbjct: 145 -----AHSSIQRILRNRHDLLNVSQGTVFIFWGPSSYMRRDGKGQVYN--NLHLLSQVLP 197
Query: 235 RTAAY-----ELLHFPKVFP----KNQKPKHP--TTGIIAITLAFYICHEVHLAG----- 278
R A+ ++L F ++F K++K + +TG +T+A +C +++ G
Sbjct: 198 RLKAFMITRHKMLQFDELFKQETGKDRKISNTWLSTGWFTMTIALELCDRINVYGMVPPD 257
Query: 279 FKYNFSDLKSPLHYY-----GNATMSLMN----KNAYHNVTAEQLFLKD 318
F + + P HYY TM L + K ++H E+ K+
Sbjct: 258 FCRDPNHPSVPYHYYEPFGPDECTMYLSHERGRKGSHHRFITEKRVFKN 306
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.142 0.447
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,476,908
Number of Sequences: 37866
Number of extensions: 546273
Number of successful extensions: 1360
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 35
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1294
Number of HSP's gapped (non-prelim): 43
length of query: 331
length of database: 18,247,518
effective HSP length: 103
effective length of query: 228
effective length of database: 14,347,320
effective search space: 3271188960
effective search space used: 3271188960
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.