Guide to the Human Genome
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Search of human proteins with 133930786

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|133930786 egf-like module-containing mucin-like receptor 3
[Homo sapiens]
         (652 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|133930786 egf-like module-containing mucin-like receptor 3 [H...  1323   0.0  
gi|23397687 egf-like module containing, mucin-like, hormone rece...   630   0.0  
gi|23397685 egf-like module containing, mucin-like, hormone rece...   606   e-173
gi|23397693 egf-like module containing, mucin-like, hormone rece...   580   e-165
gi|23397681 egf-like module containing, mucin-like, hormone rece...   568   e-162
gi|23397683 egf-like module containing, mucin-like, hormone rece...   566   e-161
gi|23397689 egf-like module containing, mucin-like, hormone rece...   556   e-158
gi|23397691 egf-like module containing, mucin-like, hormone rece...   553   e-157
gi|40807489 egf-like module containing, mucin-like, hormone rece...   453   e-127
gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens]           348   1e-95
gi|148806925 EGF, latrophilin and seven transmembrane domain con...   315   8e-86
gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens]           311   9e-85
gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens]           309   5e-84
gi|163792198 latrophilin 3 precursor [Homo sapiens]                   285   9e-77
gi|6912464 latrophilin 2 precursor [Homo sapiens]                     279   5e-75
gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]          272   6e-73
gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]          272   6e-73
gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo s...   208   1e-53
gi|45433552 G protein-coupled receptor 133 [Homo sapiens]             198   1e-50
gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo ...   197   2e-50
gi|59710093 G-protein coupled receptor 112 [Homo sapiens]             186   6e-47
gi|119943125 G protein-coupled receptor 64 isoform 3 [Homo sapiens]   182   6e-46
gi|119943116 G protein-coupled receptor 64 isoform 2 [Homo sapiens]   182   6e-46
gi|119943120 G protein-coupled receptor 64 isoform 1 [Homo sapiens]   182   6e-46
gi|119943129 G protein-coupled receptor 64 isoform 4 [Homo sapiens]   182   6e-46
gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo...   182   6e-46
gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [...   155   1e-37
gi|240120161 G protein-coupled receptor 144 [Homo sapiens]            149   1e-35
gi|4502359 brain-specific angiogenesis inhibitor 3 [Homo sapiens]     145   1e-34
gi|74048357 G protein-coupled receptor 126 alpha 1 precursor [Ho...   143   4e-34

>gi|133930786 egf-like module-containing mucin-like receptor 3 [Homo
           sapiens]
          Length = 652

 Score = 1323 bits (3425), Expect = 0.0
 Identities = 652/652 (100%), Positives = 652/652 (100%)

Query: 1   MQGPLLLPGLCFLLSLFGAVTQKTKTSCAKCPPNASCVNNTHCTCNHGYTSGSGQKLFTF 60
           MQGPLLLPGLCFLLSLFGAVTQKTKTSCAKCPPNASCVNNTHCTCNHGYTSGSGQKLFTF
Sbjct: 1   MQGPLLLPGLCFLLSLFGAVTQKTKTSCAKCPPNASCVNNTHCTCNHGYTSGSGQKLFTF 60

Query: 61  PLETCNDINECTPPYSVYCGFNAVCYNVEGSFYCQCVPGYRLHSGNEQFSNSNENTCQDT 120
           PLETCNDINECTPPYSVYCGFNAVCYNVEGSFYCQCVPGYRLHSGNEQFSNSNENTCQDT
Sbjct: 61  PLETCNDINECTPPYSVYCGFNAVCYNVEGSFYCQCVPGYRLHSGNEQFSNSNENTCQDT 120

Query: 121 TSSKTTEGRKELQKIVDKFESLLTNQTLWRTEGRQEISSTATTILRDVESKVLETALKDP 180
           TSSKTTEGRKELQKIVDKFESLLTNQTLWRTEGRQEISSTATTILRDVESKVLETALKDP
Sbjct: 121 TSSKTTEGRKELQKIVDKFESLLTNQTLWRTEGRQEISSTATTILRDVESKVLETALKDP 180

Query: 181 EQKVLKIQNDSVAIETQAITDNCSEERKTFNLNVQMNSMDIRCSDIIQGDTQGPSAIAFI 240
           EQKVLKIQNDSVAIETQAITDNCSEERKTFNLNVQMNSMDIRCSDIIQGDTQGPSAIAFI
Sbjct: 181 EQKVLKIQNDSVAIETQAITDNCSEERKTFNLNVQMNSMDIRCSDIIQGDTQGPSAIAFI 240

Query: 241 SYSSLGNIINATFFEEMDKKDQVYLNSQVVSAAIGPKRNVSLSKSVTLTFQHVKMTPSTK 300
           SYSSLGNIINATFFEEMDKKDQVYLNSQVVSAAIGPKRNVSLSKSVTLTFQHVKMTPSTK
Sbjct: 241 SYSSLGNIINATFFEEMDKKDQVYLNSQVVSAAIGPKRNVSLSKSVTLTFQHVKMTPSTK 300

Query: 301 KVFCVYWKSTGQGSQWSRDGCFLIHVNKSHTMCNCSHLSSFAVLMALTSQEEDPVLTVIT 360
           KVFCVYWKSTGQGSQWSRDGCFLIHVNKSHTMCNCSHLSSFAVLMALTSQEEDPVLTVIT
Sbjct: 301 KVFCVYWKSTGQGSQWSRDGCFLIHVNKSHTMCNCSHLSSFAVLMALTSQEEDPVLTVIT 360

Query: 361 YVGLSVSLLCLLLAALTFLLCKAIRNTSTSLHLQLSLCLFLAHLLFLVGIDRTEPKVLCS 420
           YVGLSVSLLCLLLAALTFLLCKAIRNTSTSLHLQLSLCLFLAHLLFLVGIDRTEPKVLCS
Sbjct: 361 YVGLSVSLLCLLLAALTFLLCKAIRNTSTSLHLQLSLCLFLAHLLFLVGIDRTEPKVLCS 420

Query: 421 IIAGALHYLYLAAFTWMLLEGVHLFLTARNLTVVNYSSINRLMKWIMFPVGYGVPAVTVA 480
           IIAGALHYLYLAAFTWMLLEGVHLFLTARNLTVVNYSSINRLMKWIMFPVGYGVPAVTVA
Sbjct: 421 IIAGALHYLYLAAFTWMLLEGVHLFLTARNLTVVNYSSINRLMKWIMFPVGYGVPAVTVA 480

Query: 481 ISAASWPHLYGTADRCWLHLDQGFMWSFLGPVCAIFSANLVLFILVFWILKRKLSSLNSE 540
           ISAASWPHLYGTADRCWLHLDQGFMWSFLGPVCAIFSANLVLFILVFWILKRKLSSLNSE
Sbjct: 481 ISAASWPHLYGTADRCWLHLDQGFMWSFLGPVCAIFSANLVLFILVFWILKRKLSSLNSE 540

Query: 541 VSTIQNTRMLAFKATAQLFILGCTWCLGLLQVGPAAQVMAYLFTIINSLQGFFIFLVYCL 600
           VSTIQNTRMLAFKATAQLFILGCTWCLGLLQVGPAAQVMAYLFTIINSLQGFFIFLVYCL
Sbjct: 541 VSTIQNTRMLAFKATAQLFILGCTWCLGLLQVGPAAQVMAYLFTIINSLQGFFIFLVYCL 600

Query: 601 LSQQVQKQYQKWFREIVKSKSESETYTLSSKMGPDSKPSEGDVFPGQVKRKY 652
           LSQQVQKQYQKWFREIVKSKSESETYTLSSKMGPDSKPSEGDVFPGQVKRKY
Sbjct: 601 LSQQVQKQYQKWFREIVKSKSESETYTLSSKMGPDSKPSEGDVFPGQVKRKY 652


>gi|23397687 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform d [Homo sapiens]
          Length = 681

 Score =  630 bits (1626), Expect = 0.0
 Identities = 362/676 (53%), Positives = 441/676 (65%), Gaps = 45/676 (6%)

Query: 5   LLLPGLCFLLSLFGAVTQKTKTSCAKCPPNASCVNNTHCTCNHGYTSGSGQKLFTFPLET 64
           L+    C  L+L GA TQ ++     CP ++SCVN T C CN G++S S  ++ T P+ET
Sbjct: 7   LVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFS--EIITTPMET 64

Query: 65  CNDINECTPPYSVYCGFNAVCYNVEGSFYCQCVPGYRLHSGNEQFSNSNENTCQDTTSSK 124
           C+DINEC     V CG  + C+N EGS+ C C PGY   SG + F N +ENTCQD T S 
Sbjct: 65  CDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDMTFST 124

Query: 125 TTEG----RKELQKIVDKFESL-------LTNQT----LWRTEGRQEISSTATTILRDVE 169
            T       + L +  DK + L       L N T    L   +   E      T+ R ++
Sbjct: 125 WTPPPGVHSQTLSRFFDKVQDLGRDYKPGLANNTIQSILQALDELLEAPGDLETLPR-LQ 183

Query: 170 SKVLETALKDPEQKVLK-----IQNDSVAIETQAITDNCSEERKTFNLNVQMNS----MD 220
              + + L D  + VL+     + N  +     A T+   E +K  + +V +      M 
Sbjct: 184 QHCVASHLLDGLEDVLRGLSKNLSNGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQ 243

Query: 221 IRCSDIIQGDTQGPSAIAFISYSSLGNII-NATFFEEMDKKDQVY-------------LN 266
           +  +   +    GPS +  +S   +G ++  A    E +K+  ++             L 
Sbjct: 244 LDWNQAQKSGDPGPSVVGLVSIPGMGKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILL 303

Query: 267 SQVVSAAIGPKRNVSLSKSVTLTFQHVKMTPSTKKVFCVYWKSTGQG-SQWSRDGCFLIH 325
           S V+SA +      +LS  VT TF H  + P  +KV CV+W+    G   W+  GC  I 
Sbjct: 304 SDVISAFLSNNDTQNLSSPVTFTFSHRSVIPR-QKVLCVFWEHGQNGCGHWATTGCSTIG 362

Query: 326 VNKSHTMCNCSHLSSFAVLMA-LTSQEEDPVLTVITYVGLSVSLLCLLLAALTFLLCKAI 384
              + T+C C+HLSSFAVLMA    QEEDPVLTVITY+GLSVSLLCLLLAALTFLLCKAI
Sbjct: 363 TRDTSTICRCTHLSSFAVLMAHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAI 422

Query: 385 RNTSTSLHLQLSLCLFLAHLLFLVGIDRTEPKVLCSIIAGALHYLYLAAFTWMLLEGVHL 444
           +NTSTSLHLQLSLCLFLAHLLFLV ID+T  KVLCSIIAG LHYLYLA  TWMLLE ++L
Sbjct: 423 QNTSTSLHLQLSLCLFLAHLLFLVAIDQTGHKVLCSIIAGTLHYLYLATLTWMLLEALYL 482

Query: 445 FLTARNLTVVNYSSINRLMKWIMFPVGYGVPAVTVAISAASWPHLYGTADRCWLHLDQGF 504
           FLTARNLTVVNYSSINR MK +MFPVGYGVPAVTVAISAAS PHLYGT  RCWL  ++GF
Sbjct: 483 FLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGF 542

Query: 505 MWSFLGPVCAIFSANLVLFILVFWILKRKLSSLNSEVSTIQNTRMLAFKATAQLFILGCT 564
           +W FLGPVCAIFS NLVLF++  WILK +LSSLNSEVST++NTRMLAFKATAQLFILGCT
Sbjct: 543 IWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCT 602

Query: 565 WCLGLLQVGPAAQVMAYLFTIINSLQGFFIFLVYCLLSQQVQKQYQKWFREIVKSKSESE 624
           WCLG+LQVGPAA+VMAYLFTIINSLQG FIFLVYCLLSQQV++QY KW + I K K+ESE
Sbjct: 603 WCLGILQVGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWSKGIRKLKTESE 662

Query: 625 TYTLSSKMGPD-SKPS 639
            +TLSS    D SKPS
Sbjct: 663 MHTLSSSAKADTSKPS 678


>gi|23397685 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform c [Homo sapiens]
          Length = 730

 Score =  606 bits (1563), Expect = e-173
 Identities = 361/725 (49%), Positives = 441/725 (60%), Gaps = 94/725 (12%)

Query: 5   LLLPGLCFLLSLFGAVTQKTKTSCAKCPPNASCVNNTHCTCNHGYTSGSGQKLFTFPLET 64
           L+    C  L+L GA TQ ++     CP ++SCVN T C CN G++S S  ++ T P+ET
Sbjct: 7   LVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFS--EIITTPMET 64

Query: 65  CNDINECTPPYSVYCGFNAVCYNVEGSFYCQCVPGYRLHSGNEQFSNSNENT-------- 116
           C+DINEC     V CG  + C+N EGS+ C C PGY   SG + F N +ENT        
Sbjct: 65  CDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECS 124

Query: 117 -----------------------------------------CQDTTSSKTTEG----RKE 131
                                                    C+D T S  T       + 
Sbjct: 125 SGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQT 184

Query: 132 LQKIVDKFESL-------LTNQT----LWRTEGRQEISSTATTILRDVESKVLETALKDP 180
           L +  DK + L       L N T    L   +   E      T+ R ++   + + L D 
Sbjct: 185 LSRFFDKVQDLGRDYKPGLANNTIQSILQALDELLEAPGDLETLPR-LQQHCVASHLLDG 243

Query: 181 EQKVLK-----IQNDSVAIETQAITDNCSEERKTFNLNVQMNS----MDIRCSDIIQGDT 231
            + VL+     + N  +     A T+   E +K  + +V +      M +  +   +   
Sbjct: 244 LEDVLRGLSKNLSNGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQKSGD 303

Query: 232 QGPSAIAFISYSSLGNII-NATFFEEMDKKDQVY-------------LNSQVVSAAIGPK 277
            GPS +  +S   +G ++  A    E +K+  ++             L S V+SA +   
Sbjct: 304 PGPSVVGLVSIPGMGKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSDVISAFLSNN 363

Query: 278 RNVSLSKSVTLTFQHVKMTPSTKKVFCVYWKSTGQG-SQWSRDGCFLIHVNKSHTMCNCS 336
              +LS  VT TF H  + P  +KV CV+W+    G   W+  GC  I    + T+C C+
Sbjct: 364 DTQNLSSPVTFTFSHRSVIPR-QKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCT 422

Query: 337 HLSSFAVLMA-LTSQEEDPVLTVITYVGLSVSLLCLLLAALTFLLCKAIRNTSTSLHLQL 395
           HLSSFAVLMA    QEEDPVLTVITY+GLSVSLLCLLLAALTFLLCKAI+NTSTSLHLQL
Sbjct: 423 HLSSFAVLMAHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQL 482

Query: 396 SLCLFLAHLLFLVGIDRTEPKVLCSIIAGALHYLYLAAFTWMLLEGVHLFLTARNLTVVN 455
           SLCLFLAHLLFLV ID+T  KVLCSIIAG LHYLYLA  TWMLLE ++LFLTARNLTVVN
Sbjct: 483 SLCLFLAHLLFLVAIDQTGHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVN 542

Query: 456 YSSINRLMKWIMFPVGYGVPAVTVAISAASWPHLYGTADRCWLHLDQGFMWSFLGPVCAI 515
           YSSINR MK +MFPVGYGVPAVTVAISAAS PHLYGT  RCWL  ++GF+W FLGPVCAI
Sbjct: 543 YSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAI 602

Query: 516 FSANLVLFILVFWILKRKLSSLNSEVSTIQNTRMLAFKATAQLFILGCTWCLGLLQVGPA 575
           FS NLVLF++  WILK +LSSLNSEVST++NTRMLAFKATAQLFILGCTWCLG+LQVGPA
Sbjct: 603 FSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQVGPA 662

Query: 576 AQVMAYLFTIINSLQGFFIFLVYCLLSQQVQKQYQKWFREIVKSKSESETYTLSSKMGPD 635
           A+VMAYLFTIINSLQG FIFLVYCLLSQQV++QY KW + I K K+ESE +TLSS    D
Sbjct: 663 ARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWSKGIRKLKTESEMHTLSSSAKAD 722

Query: 636 -SKPS 639
            SKPS
Sbjct: 723 TSKPS 727


>gi|23397693 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform g [Homo sapiens]
          Length = 719

 Score =  580 bits (1496), Expect = e-165
 Identities = 352/723 (48%), Positives = 432/723 (59%), Gaps = 101/723 (13%)

Query: 5   LLLPGLCFLLSLFGAVTQKTKTSCAKCPPNASCVNNTHCTCNHGYTSGSGQKLFTFPLET 64
           L+    C  L+L GA TQ ++     CP ++SCVN T C CN G++S S  ++ T P+ET
Sbjct: 7   LVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFS--EIITTPMET 64

Query: 65  CNDINECTPPYSVYCG-------------------------------------------- 80
           C+DINEC     V CG                                            
Sbjct: 65  CDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECS 124

Query: 81  -------FNAVCYNVEGSFYCQCVPGYRLHSGNEQFSNSNENTCQDTTSSKTTEG----R 129
                   + VC+N  GS+ C+C PG++   G    +N  +  C+D T S  T       
Sbjct: 125 SGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIP--NNQKDTVCEDMTFSTWTPPPGVHS 182

Query: 130 KELQKIVDKFESL-------LTNQT----LWRTEGRQEISSTATTILRDVESKVLETALK 178
           + L +  DK + L       L N T    L   +   E      T+ R ++   + + L 
Sbjct: 183 QTLSRFFDKVQDLGRDYKPGLANNTIQSILQALDELLEAPGDLETLPR-LQQHCVASHLL 241

Query: 179 DPEQKVLK-----IQNDSVAIETQAITDNCSEERKTFNLNVQMN-SMDIRCSDIIQGDTQ 232
           D  + VL+     + N  +     A T+   E +K  + +V +  +  +   D  Q    
Sbjct: 242 DGLEDVLRGLSKNLSNGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQKS 301

Query: 233 GPSAIAFISYSSLGNIINATFFEEMDKKDQVY-------------LNSQVVSAAIGPKRN 279
           G   +  +       +  A    E +K+  ++             L S V+SA +     
Sbjct: 302 GDPGMGKL-------LAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDT 354

Query: 280 VSLSKSVTLTFQHVKMTPSTKKVFCVYWKSTGQG-SQWSRDGCFLIHVNKSHTMCNCSHL 338
            +LS  VT TF H  + P  +KV CV+W+    G   W+  GC  I    + T+C C+HL
Sbjct: 355 QNLSSPVTFTFSHRSVIPR-QKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHL 413

Query: 339 SSFAVLMA-LTSQEEDPVLTVITYVGLSVSLLCLLLAALTFLLCKAIRNTSTSLHLQLSL 397
           SSFAVLMA    QEEDPVLTVITY+GLSVSLLCLLLAALTFLLCKAI+NTSTSLHLQLSL
Sbjct: 414 SSFAVLMAHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSL 473

Query: 398 CLFLAHLLFLVGIDRTEPKVLCSIIAGALHYLYLAAFTWMLLEGVHLFLTARNLTVVNYS 457
           CLFLAHLLFLV ID+T  KVLCSIIAG LHYLYLA  TWMLLE ++LFLTARNLTVVNYS
Sbjct: 474 CLFLAHLLFLVAIDQTGHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYS 533

Query: 458 SINRLMKWIMFPVGYGVPAVTVAISAASWPHLYGTADRCWLHLDQGFMWSFLGPVCAIFS 517
           SINR MK +MFPVGYGVPAVTVAISAAS PHLYGT  RCWL  ++GF+W FLGPVCAIFS
Sbjct: 534 SINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFS 593

Query: 518 ANLVLFILVFWILKRKLSSLNSEVSTIQNTRMLAFKATAQLFILGCTWCLGLLQVGPAAQ 577
            NLVLF++  WILK +LSSLNSEVST++NTRMLAFKATAQLFILGCTWCLG+LQVGPAA+
Sbjct: 594 VNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQVGPAAR 653

Query: 578 VMAYLFTIINSLQGFFIFLVYCLLSQQVQKQYQKWFREIVKSKSESETYTLSSKMGPD-S 636
           VMAYLFTIINSLQG FIFLVYCLLSQQV++QY KW + I K K+ESE +TLSS    D S
Sbjct: 654 VMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWSKGIRKLKTESEMHTLSSSAKADTS 713

Query: 637 KPS 639
           KPS
Sbjct: 714 KPS 716


>gi|23397681 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform a [Homo sapiens]
          Length = 823

 Score =  568 bits (1465), Expect = e-162
 Identities = 336/654 (51%), Positives = 413/654 (63%), Gaps = 52/654 (7%)

Query: 31  CPPNASCVNNT---HCTCNHGYTSGSGQKLFTFPLET-CNDINECTPPYSVYCGFNAVCY 86
           C  +  C+NN     C C  G+    G      P  T C D++EC+      C  + VC+
Sbjct: 174 CHSSTHCLNNVGSYQCRCRPGWQPIPGSP--NGPNNTVCEDVDECSSGQH-QCDSSTVCF 230

Query: 87  NVEGSFYCQCVPGYRLHSGNEQFSNSNENTCQDTTSSKTTEG----RKELQKIVDKFESL 142
           N  GS+ C+C PG++   G    +N  +  C+D T S  T       + L +  DK + L
Sbjct: 231 NTVGSYSCRCRPGWKPRHGIP--NNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDL 288

Query: 143 -------LTNQT----LWRTEGRQEISSTATTILRDVESKVLETALKDPEQKVLK----- 186
                  L N T    L   +   E      T+ R ++   + + L D  + VL+     
Sbjct: 289 GRDYKPGLANNTIQSILQALDELLEAPGDLETLPR-LQQHCVASHLLDGLEDVLRGLSKN 347

Query: 187 IQNDSVAIETQAITDNCSEERKTFNLNVQMNS----MDIRCSDIIQGDTQGPSAIAFISY 242
           + N  +     A T+   E +K  + +V +      M +  +   +    GPS +  +S 
Sbjct: 348 LSNGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQKSGDPGPSVVGLVSI 407

Query: 243 SSLGNII-NATFFEEMDKKDQVY-------------LNSQVVSAAIGPKRNVSLSKSVTL 288
             +G ++  A    E +K+  ++             L S V+SA +      +LS  VT 
Sbjct: 408 PGMGKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDTQNLSSPVTF 467

Query: 289 TFQHVKMTPSTKKVFCVYWKSTGQG-SQWSRDGCFLIHVNKSHTMCNCSHLSSFAVLMA- 346
           TF H  + P  +KV CV+W+    G   W+  GC  I    + T+C C+HLSSFAVLMA 
Sbjct: 468 TFSHRSVIPR-QKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLSSFAVLMAH 526

Query: 347 LTSQEEDPVLTVITYVGLSVSLLCLLLAALTFLLCKAIRNTSTSLHLQLSLCLFLAHLLF 406
              QEEDPVLTVITY+GLSVSLLCLLLAALTFLLCKAI+NTSTSLHLQLSLCLFLAHLLF
Sbjct: 527 YDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHLLF 586

Query: 407 LVGIDRTEPKVLCSIIAGALHYLYLAAFTWMLLEGVHLFLTARNLTVVNYSSINRLMKWI 466
           LV ID+T  KVLCSIIAG LHYLYLA  TWMLLE ++LFLTARNLTVVNYSSINR MK +
Sbjct: 587 LVAIDQTGHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKL 646

Query: 467 MFPVGYGVPAVTVAISAASWPHLYGTADRCWLHLDQGFMWSFLGPVCAIFSANLVLFILV 526
           MFPVGYGVPAVTVAISAAS PHLYGT  RCWL  ++GF+W FLGPVCAIFS NLVLF++ 
Sbjct: 647 MFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSVNLVLFLVT 706

Query: 527 FWILKRKLSSLNSEVSTIQNTRMLAFKATAQLFILGCTWCLGLLQVGPAAQVMAYLFTII 586
            WILK +LSSLNSEVST++NTRMLAFKATAQLFILGCTWCLG+LQVGPAA+VMAYLFTII
Sbjct: 707 LWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQVGPAARVMAYLFTII 766

Query: 587 NSLQGFFIFLVYCLLSQQVQKQYQKWFREIVKSKSESETYTLSSKMGPD-SKPS 639
           NSLQG FIFLVYCLLSQQV++QY KW + I K K+ESE +TLSS    D SKPS
Sbjct: 767 NSLQGVFIFLVYCLLSQQVREQYGKWSKGIRKLKTESEMHTLSSSAKADTSKPS 820



 Score =  110 bits (275), Expect = 4e-24
 Identities = 54/115 (46%), Positives = 71/115 (61%), Gaps = 2/115 (1%)

Query: 5   LLLPGLCFLLSLFGAVTQKTKTSCAKCPPNASCVNNTHCTCNHGYTSGSGQKLFTFPLET 64
           L+    C  L+L GA TQ ++     CP ++SCVN T C CN G++S S  ++ T P+ET
Sbjct: 7   LVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFS--EIITTPMET 64

Query: 65  CNDINECTPPYSVYCGFNAVCYNVEGSFYCQCVPGYRLHSGNEQFSNSNENTCQD 119
           C+DINEC     V CG  + C+N EGS+ C C PGY   SG + F N +ENTCQD
Sbjct: 65  CDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQD 119


>gi|23397683 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform b [Homo sapiens]
          Length = 774

 Score =  566 bits (1459), Expect = e-161
 Identities = 335/653 (51%), Positives = 412/653 (63%), Gaps = 55/653 (8%)

Query: 31  CPPNASCVNNTH---CTCNHGYTSGSGQKLFTFPLETCNDINECTPPYSVYCGFNAVCYN 87
           C    +CVN      C C  G+      KL     + C D++EC+      C  + VC+N
Sbjct: 130 CKSYGTCVNTLGSYTCQCLPGF------KLKPEDPKLCTDVDECSSGQH-QCDSSTVCFN 182

Query: 88  VEGSFYCQCVPGYRLHSGNEQFSNSNENTCQDTTSSKTTEG----RKELQKIVDKFESL- 142
             GS+ C+C PG++   G    +N  +  C+D T S  T       + L +  DK + L 
Sbjct: 183 TVGSYSCRCRPGWKPRHGIP--NNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLG 240

Query: 143 ------LTNQT----LWRTEGRQEISSTATTILRDVESKVLETALKDPEQKVLK-----I 187
                 L N T    L   +   E      T+ R ++   + + L D  + VL+     +
Sbjct: 241 RDYKPGLANNTIQSILQALDELLEAPGDLETLPR-LQQHCVASHLLDGLEDVLRGLSKNL 299

Query: 188 QNDSVAIETQAITDNCSEERKTFNLNVQMNS----MDIRCSDIIQGDTQGPSAIAFISYS 243
            N  +     A T+   E +K  + +V +      M +  +   +    GPS +  +S  
Sbjct: 300 SNGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQKSGDPGPSVVGLVSIP 359

Query: 244 SLGNII-NATFFEEMDKKDQVY-------------LNSQVVSAAIGPKRNVSLSKSVTLT 289
            +G ++  A    E +K+  ++             L S V+SA +      +LS  VT T
Sbjct: 360 GMGKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDTQNLSSPVTFT 419

Query: 290 FQHVKMTPSTKKVFCVYWKSTGQG-SQWSRDGCFLIHVNKSHTMCNCSHLSSFAVLMA-L 347
           F H  + P  +KV CV+W+    G   W+  GC  I    + T+C C+HLSSFAVLMA  
Sbjct: 420 FSHRSVIPR-QKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLSSFAVLMAHY 478

Query: 348 TSQEEDPVLTVITYVGLSVSLLCLLLAALTFLLCKAIRNTSTSLHLQLSLCLFLAHLLFL 407
             QEEDPVLTVITY+GLSVSLLCLLLAALTFLLCKAI+NTSTSLHLQLSLCLFLAHLLFL
Sbjct: 479 DVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHLLFL 538

Query: 408 VGIDRTEPKVLCSIIAGALHYLYLAAFTWMLLEGVHLFLTARNLTVVNYSSINRLMKWIM 467
           V ID+T  KVLCSIIAG LHYLYLA  TWMLLE ++LFLTARNLTVVNYSSINR MK +M
Sbjct: 539 VAIDQTGHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLM 598

Query: 468 FPVGYGVPAVTVAISAASWPHLYGTADRCWLHLDQGFMWSFLGPVCAIFSANLVLFILVF 527
           FPVGYGVPAVTVAISAAS PHLYGT  RCWL  ++GF+W FLGPVCAIFS NLVLF++  
Sbjct: 599 FPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTL 658

Query: 528 WILKRKLSSLNSEVSTIQNTRMLAFKATAQLFILGCTWCLGLLQVGPAAQVMAYLFTIIN 587
           WILK +LSSLNSEVST++NTRMLAFKATAQLFILGCTWCLG+LQVGPAA+VMAYLFTIIN
Sbjct: 659 WILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQVGPAARVMAYLFTIIN 718

Query: 588 SLQGFFIFLVYCLLSQQVQKQYQKWFREIVKSKSESETYTLSSKMGPD-SKPS 639
           SLQG FIFLVYCLLSQQV++QY KW + I K K+ESE +TLSS    D SKPS
Sbjct: 719 SLQGVFIFLVYCLLSQQVREQYGKWSKGIRKLKTESEMHTLSSSAKADTSKPS 771



 Score =  110 bits (275), Expect = 4e-24
 Identities = 54/115 (46%), Positives = 71/115 (61%), Gaps = 2/115 (1%)

Query: 5   LLLPGLCFLLSLFGAVTQKTKTSCAKCPPNASCVNNTHCTCNHGYTSGSGQKLFTFPLET 64
           L+    C  L+L GA TQ ++     CP ++SCVN T C CN G++S S  ++ T P+ET
Sbjct: 7   LVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFS--EIITTPMET 64

Query: 65  CNDINECTPPYSVYCGFNAVCYNVEGSFYCQCVPGYRLHSGNEQFSNSNENTCQD 119
           C+DINEC     V CG  + C+N EGS+ C C PGY   SG + F N +ENTCQD
Sbjct: 65  CDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQD 119


>gi|23397689 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform e [Homo sapiens]
          Length = 812

 Score =  556 bits (1432), Expect = e-158
 Identities = 333/650 (51%), Positives = 407/650 (62%), Gaps = 55/650 (8%)

Query: 31  CPPNASCVNNT---HCTCNHGYTSGSGQKLFTFPLET-CNDINECTPPYSVYCGFNAVCY 86
           C  +  C+NN     C C  G+    G      P  T C D++EC+      C  + VC+
Sbjct: 174 CHSSTHCLNNVGSYQCRCRPGWQPIPGSP--NGPNNTVCEDVDECSSGQH-QCDSSTVCF 230

Query: 87  NVEGSFYCQCVPGYRLHSGNEQFSNSNENTCQDTTSSKTTEG----RKELQKIVDKFESL 142
           N  GS+ C+C PG++   G    +N  +  C+D T S  T       + L +  DK + L
Sbjct: 231 NTVGSYSCRCRPGWKPRHGIP--NNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDL 288

Query: 143 -------LTNQT----LWRTEGRQEISSTATTILRDVESKVLETALKDPEQKVLK----- 186
                  L N T    L   +   E      T+ R ++   + + L D  + VL+     
Sbjct: 289 GRDYKPGLANNTIQSILQALDELLEAPGDLETLPR-LQQHCVASHLLDGLEDVLRGLSKN 347

Query: 187 IQNDSVAIETQAITDNCSEERKTFNLNVQMN-SMDIRCSDIIQGDTQGPSAIAFISYSSL 245
           + N  +     A T+   E +K  + +V +  +  +   D  Q    G   +  +     
Sbjct: 348 LSNGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQKSGDPGMGKL----- 402

Query: 246 GNIINATFFEEMDKKDQVY-------------LNSQVVSAAIGPKRNVSLSKSVTLTFQH 292
             +  A    E +K+  ++             L S V+SA +      +LS  VT TF H
Sbjct: 403 --LAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDTQNLSSPVTFTFSH 460

Query: 293 VKMTPSTKKVFCVYWKSTGQG-SQWSRDGCFLIHVNKSHTMCNCSHLSSFAVLMA-LTSQ 350
             + P  +KV CV+W+    G   W+  GC  I    + T+C C+HLSSFAVLMA    Q
Sbjct: 461 RSVIPR-QKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLSSFAVLMAHYDVQ 519

Query: 351 EEDPVLTVITYVGLSVSLLCLLLAALTFLLCKAIRNTSTSLHLQLSLCLFLAHLLFLVGI 410
           EEDPVLTVITY+GLSVSLLCLLLAALTFLLCKAI+NTSTSLHLQLSLCLFLAHLLFLV I
Sbjct: 520 EEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHLLFLVAI 579

Query: 411 DRTEPKVLCSIIAGALHYLYLAAFTWMLLEGVHLFLTARNLTVVNYSSINRLMKWIMFPV 470
           D+T  KVLCSIIAG LHYLYLA  TWMLLE ++LFLTARNLTVVNYSSINR MK +MFPV
Sbjct: 580 DQTGHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPV 639

Query: 471 GYGVPAVTVAISAASWPHLYGTADRCWLHLDQGFMWSFLGPVCAIFSANLVLFILVFWIL 530
           GYGVPAVTVAISAAS PHLYGT  RCWL  ++GF+W FLGPVCAIFS NLVLF++  WIL
Sbjct: 640 GYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWIL 699

Query: 531 KRKLSSLNSEVSTIQNTRMLAFKATAQLFILGCTWCLGLLQVGPAAQVMAYLFTIINSLQ 590
           K +LSSLNSEVST++NTRMLAFKATAQLFILGCTWCLG+LQVGPAA+VMAYLFTIINSLQ
Sbjct: 700 KNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQVGPAARVMAYLFTIINSLQ 759

Query: 591 GFFIFLVYCLLSQQVQKQYQKWFREIVKSKSESETYTLSSKMGPD-SKPS 639
           G FIFLVYCLLSQQV++QY KW + I K K+ESE +TLSS    D SKPS
Sbjct: 760 GVFIFLVYCLLSQQVREQYGKWSKGIRKLKTESEMHTLSSSAKADTSKPS 809



 Score =  110 bits (275), Expect = 4e-24
 Identities = 54/115 (46%), Positives = 71/115 (61%), Gaps = 2/115 (1%)

Query: 5   LLLPGLCFLLSLFGAVTQKTKTSCAKCPPNASCVNNTHCTCNHGYTSGSGQKLFTFPLET 64
           L+    C  L+L GA TQ ++     CP ++SCVN T C CN G++S S  ++ T P+ET
Sbjct: 7   LVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFS--EIITTPMET 64

Query: 65  CNDINECTPPYSVYCGFNAVCYNVEGSFYCQCVPGYRLHSGNEQFSNSNENTCQD 119
           C+DINEC     V CG  + C+N EGS+ C C PGY   SG + F N +ENTCQD
Sbjct: 65  CDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQD 119


>gi|23397691 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform f [Homo sapiens]
          Length = 763

 Score =  553 bits (1426), Expect = e-157
 Identities = 332/649 (51%), Positives = 406/649 (62%), Gaps = 58/649 (8%)

Query: 31  CPPNASCVNNTH---CTCNHGYTSGSGQKLFTFPLETCNDINECTPPYSVYCGFNAVCYN 87
           C    +CVN      C C  G+      KL     + C D++EC+      C  + VC+N
Sbjct: 130 CKSYGTCVNTLGSYTCQCLPGF------KLKPEDPKLCTDVDECSSGQH-QCDSSTVCFN 182

Query: 88  VEGSFYCQCVPGYRLHSGNEQFSNSNENTCQDTTSSKTTEG----RKELQKIVDKFESL- 142
             GS+ C+C PG++   G    +N  +  C+D T S  T       + L +  DK + L 
Sbjct: 183 TVGSYSCRCRPGWKPRHGIP--NNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLG 240

Query: 143 ------LTNQT----LWRTEGRQEISSTATTILRDVESKVLETALKDPEQKVLK-----I 187
                 L N T    L   +   E      T+ R ++   + + L D  + VL+     +
Sbjct: 241 RDYKPGLANNTIQSILQALDELLEAPGDLETLPR-LQQHCVASHLLDGLEDVLRGLSKNL 299

Query: 188 QNDSVAIETQAITDNCSEERKTFNLNVQMN-SMDIRCSDIIQGDTQGPSAIAFISYSSLG 246
            N  +     A T+   E +K  + +V +  +  +   D  Q    G   +  +      
Sbjct: 300 SNGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQKSGDPGMGKL------ 353

Query: 247 NIINATFFEEMDKKDQVY-------------LNSQVVSAAIGPKRNVSLSKSVTLTFQHV 293
            +  A    E +K+  ++             L S V+SA +      +LS  VT TF H 
Sbjct: 354 -LAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDTQNLSSPVTFTFSHR 412

Query: 294 KMTPSTKKVFCVYWKSTGQG-SQWSRDGCFLIHVNKSHTMCNCSHLSSFAVLMA-LTSQE 351
            + P  +KV CV+W+    G   W+  GC  I    + T+C C+HLSSFAVLMA    QE
Sbjct: 413 SVIPR-QKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLSSFAVLMAHYDVQE 471

Query: 352 EDPVLTVITYVGLSVSLLCLLLAALTFLLCKAIRNTSTSLHLQLSLCLFLAHLLFLVGID 411
           EDPVLTVITY+GLSVSLLCLLLAALTFLLCKAI+NTSTSLHLQLSLCLFLAHLLFLV ID
Sbjct: 472 EDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHLLFLVAID 531

Query: 412 RTEPKVLCSIIAGALHYLYLAAFTWMLLEGVHLFLTARNLTVVNYSSINRLMKWIMFPVG 471
           +T  KVLCSIIAG LHYLYLA  TWMLLE ++LFLTARNLTVVNYSSINR MK +MFPVG
Sbjct: 532 QTGHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVG 591

Query: 472 YGVPAVTVAISAASWPHLYGTADRCWLHLDQGFMWSFLGPVCAIFSANLVLFILVFWILK 531
           YGVPAVTVAISAAS PHLYGT  RCWL  ++GF+W FLGPVCAIFS NLVLF++  WILK
Sbjct: 592 YGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILK 651

Query: 532 RKLSSLNSEVSTIQNTRMLAFKATAQLFILGCTWCLGLLQVGPAAQVMAYLFTIINSLQG 591
            +LSSLNSEVST++NTRMLAFKATAQLFILGCTWCLG+LQVGPAA+VMAYLFTIINSLQG
Sbjct: 652 NRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQVGPAARVMAYLFTIINSLQG 711

Query: 592 FFIFLVYCLLSQQVQKQYQKWFREIVKSKSESETYTLSSKMGPD-SKPS 639
            FIFLVYCLLSQQV++QY KW + I K K+ESE +TLSS    D SKPS
Sbjct: 712 VFIFLVYCLLSQQVREQYGKWSKGIRKLKTESEMHTLSSSAKADTSKPS 760



 Score =  110 bits (275), Expect = 4e-24
 Identities = 54/115 (46%), Positives = 71/115 (61%), Gaps = 2/115 (1%)

Query: 5   LLLPGLCFLLSLFGAVTQKTKTSCAKCPPNASCVNNTHCTCNHGYTSGSGQKLFTFPLET 64
           L+    C  L+L GA TQ ++     CP ++SCVN T C CN G++S S  ++ T P+ET
Sbjct: 7   LVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFS--EIITTPMET 64

Query: 65  CNDINECTPPYSVYCGFNAVCYNVEGSFYCQCVPGYRLHSGNEQFSNSNENTCQD 119
           C+DINEC     V CG  + C+N EGS+ C C PGY   SG + F N +ENTCQD
Sbjct: 65  CDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQD 119


>gi|40807489 egf-like module containing, mucin-like, hormone
           receptor-like sequence 1 [Homo sapiens]
          Length = 886

 Score =  453 bits (1165), Expect = e-127
 Identities = 244/644 (37%), Positives = 370/644 (57%), Gaps = 50/644 (7%)

Query: 31  CPPNASCVNNT---HCTCNHGYTSGSGQKLFTFPLETCNDINECTPPYSVYCGFNAVCYN 87
           CP N++C N      CTC+ G+   +GQ  FT     C DI+EC    S  CG N++C N
Sbjct: 229 CPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPST-CGPNSICTN 287

Query: 88  VEGSFYCQCVPGYRLHSGNEQ----FS---------------NSNENTCQDTTS------ 122
             GS+ C C+ G+  +    Q    FS               N     CQ+ T+      
Sbjct: 288 ALGSYSCGCIAGFHPNPEGSQKDGNFSCQRVLFKCKEDVIPDNKQIQQCQEGTAVKPAYV 347

Query: 123 -------------SKTTEGRK---ELQKIVDKFESLLTNQTLWRTEGRQEISSTATTILR 166
                         K  E +     L+   + F  +L   + W    ++E SS AT  L 
Sbjct: 348 SFCAQINNIFSVLDKVCENKTTVVSLKNTTESFVPVLKQISTWTKFTKEETSSLATVFLE 407

Query: 167 DVESKVLETALKDPEQKVLKIQNDSVAIETQAITDNCSEERKTFNLNVQMNSMDIRCSDI 226
            VES  L +  K        ++ + + IE++ I   CSEE  T +L  + + M I CS I
Sbjct: 408 SVESMTLASFWKPSANITPAVRTEYLDIESKVINKECSEENVTLDLVAKGDKMKIGCSTI 467

Query: 227 IQGDTQGPSAIAFISYSSLGNIINATFFEEMD-----KKDQVYLNSQVVSAAIGPKRNVS 281
            + ++   + +AF+S+  + +++N  FF++        + ++ +NS+VV   +  ++   
Sbjct: 468 EESESTETTGVAFVSFVGMESVLNERFFKDHQAPLTTSEIKLKMNSRVVGGIMTGEKKDG 527

Query: 282 LSKSVTLTFQHVKMTPSTKKVFCVYWKSTGQGSQWSRDGCFLIHVNKSHTMCNCSHLSSF 341
            S  +  T ++++     ++  CV W +  +G +W+  GC ++  ++++T+C+C+ +++ 
Sbjct: 528 FSDPIIYTLENIQPKQKFERPICVSWSTDVKGGRWTSFGCVILEASETYTICSCNQMANL 587

Query: 342 AVLMALTSQEEDPVLTVITYVGLSVSLLCLLLAALTFLLCKAIRNTSTSLHLQLSLCLFL 401
           AV+MA      D  L +I++VG+ +SL+CL+LA  TFLLC++IRN +T LHL L +CL L
Sbjct: 588 AVIMASGELTMDFSLYIISHVGIIISLVCLVLAIATFLLCRSIRNHNTYLHLHLCVCLLL 647

Query: 402 AHLLFLVGIDRTEPKVLCSIIAGALHYLYLAAFTWMLLEGVHLFLTARNLTVVNYSSINR 461
           A  LFL GI +T+ K+ C+IIAG LHYL+LA F WML+E V LFL  RNL VVNY S   
Sbjct: 648 AKTLFLAGIHKTDNKMGCAIIAGFLHYLFLACFFWMLVEAVILFLMVRNLKVVNYFSSRN 707

Query: 462 LMKWIMFPVGYGVPAVTVAISAASWPHLYGTADRCWLHLDQGFMWSFLGPVCAIFSANLV 521
           +    +   GYG+P + V ISA+  P  YG  +RCWL+ + GF+WSFLGPVC +   N +
Sbjct: 708 IKMLHICAFGYGLPMLVVVISASVQPQGYGMHNRCWLNTETGFIWSFLGPVCTVIVINSL 767

Query: 522 LFILVFWILKRKLSSLNSEVSTIQNTRMLAFKATAQLFILGCTWCLGLLQVGPAAQVMAY 581
           L     WIL+++LSS+N+EVST+++TR+L FKA AQLFILGC+W LG+ Q+GP A VMAY
Sbjct: 768 LLTWTLWILRQRLSSVNAEVSTLKDTRLLTFKAFAQLFILGCSWVLGIFQIGPVAGVMAY 827

Query: 582 LFTIINSLQGFFIFLVYCLLSQQVQKQYQKWFREIVKSKSESET 625
           LFTIINSLQG FIFL++CLL+ QV+++Y++W     K  S+S+T
Sbjct: 828 LFTIINSLQGAFIFLIHCLLNGQVREEYKRWITGKTKPSSQSQT 871



 Score = 66.6 bits (161), Expect = 7e-11
 Identities = 34/92 (36%), Positives = 47/92 (51%), Gaps = 8/92 (8%)

Query: 31  CPPNASC---VNNTHCTCNHGYTSGSGQKLFTFPLETCNDINECTPPYSVYCGFNAVCYN 87
           CP +A+C   V N  C CN G+ S SG   F     +C DI+ECT      C  N+ C N
Sbjct: 182 CPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTE----MCPINSTCTN 237

Query: 88  VEGSFYCQCVPGYRLHSGNEQFSNSNENTCQD 119
             GS++C C PG+   +G   F++     C+D
Sbjct: 238 TPGSYFCTCHPGFAPSNGQLNFTDQGVE-CRD 268



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 42/134 (31%), Positives = 60/134 (44%), Gaps = 13/134 (9%)

Query: 5   LLLPGLCFLLSLFGAV--TQKTKTS------CAKCPPNASCVNNT---HCTCNHGYTSGS 53
           LL  G C + S  G +  T+K  T          CP  A+C N     +C C  G+ S +
Sbjct: 7   LLFWGCCVMHSWEGHIRPTRKPNTKGNNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSN 66

Query: 54  GQKLFTFPLETCNDINECTPPYSVYCGFNAVCYNVEGSFYCQCVPGYRLHSGNEQFSNSN 113
           GQ  F  P   C DI+EC+      CG N+ C N+ G + C C+ G+   +GN+      
Sbjct: 67  GQNHFKDPGVRCKDIDECSQSPQP-CGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKP 125

Query: 114 EN-TCQDTTSSKTT 126
            N +C D     T+
Sbjct: 126 GNFSCTDINECLTS 139



 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 29/92 (31%), Positives = 46/92 (50%), Gaps = 15/92 (16%)

Query: 31  CPPNASCVNNT---HCTCNHGYTSGSGQKLFTFPLETCNDINECTPPYSVYCGFNAVCYN 87
           CP ++ CVN+     C+C  G+ S +          TC D++EC  P +  C  +A C N
Sbjct: 142 CPEHSDCVNSMGSYSCSCQVGFISRNS---------TCEDVDECADPRA--CPEHATCNN 190

Query: 88  VEGSFYCQCVPGYRLHSGNEQFSNSNENTCQD 119
             G++ C C PG+   SG+  F    + +C+D
Sbjct: 191 TVGNYSCFCNPGFESSSGHLSFQGL-KASCED 221



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 32/97 (32%), Positives = 45/97 (46%), Gaps = 23/97 (23%)

Query: 31  CPPNASCVNNT---HCTCNHGYTSGSGQ-----KLFTFPLETCNDINECTPPYSVYCGFN 82
           C PN+SC N +    C+C  G++S +G      K   F   +C DINEC    S  C  +
Sbjct: 91  CGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNF---SCTDINECLT--SSVCPEH 145

Query: 83  AVCYNVEGSFYCQCVPGYRLHSGNEQFSNSNENTCQD 119
           + C N  GS+ C C  G+           S  +TC+D
Sbjct: 146 SDCVNSMGSYSCSCQVGF----------ISRNSTCED 172


>gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens]
          Length = 742

 Score =  348 bits (892), Expect = 1e-95
 Identities = 232/737 (31%), Positives = 350/737 (47%), Gaps = 132/737 (17%)

Query: 11  CFLLSLFGAVTQKTKTSCAKCPPNASCVNNTHCTCNHGYTSGSGQKLFTFPLETCNDINE 70
           C  L+L GA TQ ++     CP N+SCVN T C CN G++S S  ++ T P ETC+DINE
Sbjct: 10  CVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFS--EIITTPTETCDDINE 67

Query: 71  CTPPYSVYCGFNAVCYNVEGSFYCQCVPGYRLHSGNEQF--------------------- 109
           C  P  V CG  + C+N EGS+ C C PGY   SG + F                     
Sbjct: 68  CATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECSSGQHQC 127

Query: 110 ----------------------------SNSNENTCQDTTSSKTTEG----RKELQKIVD 137
                                       +N  +  C+D T S  T       + L +  D
Sbjct: 128 DSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFD 187

Query: 138 KFESLLTNQTLWRTEGRQEISSTATTILRDVESKVLET--------ALKDPEQKVLKIQ- 188
           K + L          GR   +S+A   +++V   V E         AL  P + ++  Q 
Sbjct: 188 KVQDL----------GRDSKTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQL 237

Query: 189 ----NDSVAIETQAITDN--------------CSEERKTFNLNVQMNSMDIRCSDIIQGD 230
                D + I  +++                   +ER   N+ +  +S  ++ +  +   
Sbjct: 238 LSNLEDIMRILAKSLPKGPFTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAG 297

Query: 231 TQ--GPSAIAFISYSSLGNIINATFFEEMDKK----DQVYLNS----------QVVSAAI 274
            +  GP+    +S  ++  ++         KK    +++Y +S           V S  +
Sbjct: 298 AEDPGPAVAGILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFL 357

Query: 275 GPKRNVSLSKSVTLTFQHVKMT-------PSTKKVF--------CVYWKS-TGQGSQWSR 318
                  L+  +   F H++ +       P  K V         C +WKS + +G  W+ 
Sbjct: 358 SHNNTKELNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWAT 417

Query: 319 DGCFLIHVNKSHTMCNCSHLSSFAVLMALTSQEEDPVLTVITYVGLSVSLLCLLLAALTF 378
           +GC ++      T C CSHLSSFA+LMA     ED  LT+IT VGL++SL CLLL  LTF
Sbjct: 418 EGCQVLGSKNGSTTCQCSHLSSFAILMA-HYDVEDWKLTLITRVGLALSLFCLLLCILTF 476

Query: 379 LLCKAIRNTSTSLHLQLSLCLFLAHLLFLVGIDRTEPKV--LCSIIAGALHYLYLAAFTW 436
           LL + I+ + T++HL L +CLF+   +FL GI+    +V   C ++AG LHY +LAAF W
Sbjct: 477 LLVRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCW 536

Query: 437 MLLEGVHLFLTARNLTVVNYSSINRLMKWIMFPVGYGVPAVTVAISAASWPHLYGTADRC 496
           M LEG+ L+     L V  +       +W+   +GYGVP + V +SAA +   YG    C
Sbjct: 537 MSLEGLELYF----LVVRVFQGQGLSTRWLCL-IGYGVPLLIVGVSAAIYSKGYGRPRYC 591

Query: 497 WLHLDQGFMWSFLGPVCAIFSANLVLFILVFWILKRKLSSLNSEVSTIQNTRMLAFKATA 556
           WL  +QGF+WSFLGPV  I   N V+F+   W L +K S +N ++  ++  R L   A A
Sbjct: 592 WLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIA 651

Query: 557 QLFILGCTWCLGLLQVGPAAQVMAYLFTIINSLQGFFIFLVYCLLSQQVQKQYQKWFREI 616
           QLF+LGCTW  GL      + V+ Y+FTI+N LQG F++L++CLL+++V+++Y+KW   +
Sbjct: 652 QLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWACLV 711

Query: 617 VKSKSESETYTLSSKMG 633
                 SE  + +S  G
Sbjct: 712 AGGSKYSEFTSTTSGTG 728


>gi|148806925 EGF, latrophilin and seven transmembrane domain
           containing 1 [Homo sapiens]
          Length = 690

 Score =  315 bits (807), Expect = 8e-86
 Identities = 222/695 (31%), Positives = 335/695 (48%), Gaps = 109/695 (15%)

Query: 13  LLSLFGAVTQKTKT-SCAKCP--PNASC-VNN--THCTCNHGYTSGSGQKLFTFPLETCN 66
           LL +F  +   + T +C K P  PNA C + N    C CN G+ SG+G  +       C 
Sbjct: 6   LLVVFSTLLNCSYTQNCTKTPCLPNAKCEIRNGIEACYCNMGF-SGNGVTI-------CE 57

Query: 67  DINECTPPYSVYCGFNAVCYNVEGSFYCQCVPGYRLHSGNEQFSNSNENTCQDTTSSK-- 124
           D NEC    +  CG NA C N EGS+YC CVPG+R  S  ++F  ++   C +  ++   
Sbjct: 58  DDNECGN-LTQSCGENANCTNTEGSYYCMCVPGFRSSSNQDRFITNDGTVCIENVNANCH 116

Query: 125 ------TTEGRKELQKIVDKFESLLTNQTLWRTEGRQ----------EISSTATTIL--R 166
                      K L KI    E +   Q ++R               EI + ++++L  +
Sbjct: 117 LDNVCIAANINKTLTKIRSIKEPVALLQEVYRNSVTDLSPTDIITYIEILAESSSLLGYK 176

Query: 167 DVESKVLETALKDPEQKVLKIQNDSVAIETQAITDNCSEERKTFNLNVQMNSMD---IRC 223
           +      +T       + +K  N+ V  +T  + D  S   +  +L   M++++   +R 
Sbjct: 177 NNTISAKDTLSNSTLTEFVKTVNNFVQRDTFVVWDKLSVNHRRTHLTKLMHTVEQATLRI 236

Query: 224 SDIIQGDTQ-----------------------------------------------GPSA 236
           S   Q  T+                                               G  A
Sbjct: 237 SQSFQKTTEFDTNSTDIALKVFFFDSYNMKHIHPHMNMDGDYINIFPKRKAAYDSNGNVA 296

Query: 237 IAFISYSSLGNIINATFFEEMDKKDQVYLNSQVVSAAIGPKRNVSLS---------KSVT 287
           +AF+ Y S+G +++++  +    K Q Y NS+     I    +VS+S         + +T
Sbjct: 297 VAFVYYKSIGPLLSSS--DNFLLKPQNYDNSEEEERVISSVISVSMSSNPPTLYELEKIT 354

Query: 288 LTFQHVKMTPSTKKVFCVYWK---STGQGSQWSRDGCFLIHVNKSHTMCNCSHLSSFAVL 344
            T  H K+T   + + C +W     T  GS WS +GC L + N++HT C C+HL+ FA+L
Sbjct: 355 FTLSHRKVTDRYRSL-CAFWNYSPDTMNGS-WSSEGCELTYSNETHTSCRCNHLTHFAIL 412

Query: 345 MALTSQ---EEDPVLTVITYVGLSVSLLCLLLAALTFLLCKAIRNTSTSLHLQLSLCLFL 401
           M+       ++  +LT IT +G+ +SL+CL +   TF     I++T T++H  L   LFL
Sbjct: 413 MSSGPSIGIKDYNILTRITQLGIIISLICLAICIFTFWFFSEIQSTRTTIHKNLCCSLFL 472

Query: 402 AHLLFLVGIDRTEPKVLCSIIAGALHYLYLAAFTWMLLEGVHLFLTARNLTVVNYSSINR 461
           A L+FLVGI+    K+ CSIIAG LHY +LAAF WM +EG+HL+     L VV       
Sbjct: 473 AELVFLVGINTNTNKLFCSIIAGLLHYFFLAAFAWMCIEGIHLY-----LIVVGVIYNKG 527

Query: 462 LMKWIMFPVGYGVPAVTVAISAASWPHLYGTADRCWLHLDQGFMWSFLGPVCAIFSANLV 521
            +    +  GY  PAV V  SAA     YGT   CWL  +  F+WSF+GP C I   NL+
Sbjct: 528 FLHKNFYIFGYLSPAVVVGFSAALGYRYYGTTKVCWLSTENNFIWSFIGPACLIILVNLL 587

Query: 522 LFILVFWILKRKLSSLNSEVSTIQNTRMLAFKATAQLFILGCTWCLGLLQVGPAAQVMAY 581
            F ++ + + R  + L  EVS  +N R  A  A A LF+LG TW  G+L V  A+ V AY
Sbjct: 588 AFGVIIYKVFRHTAGLKPEVSCFENIRSCARGALALLFLLGTTWIFGVLHVVHASVVTAY 647

Query: 582 LFTIINSLQGFFIFLVYCLLSQQVQKQYQKWFREI 616
           LFT+ N+ QG FIFL  C+LS+++Q++Y + F+ +
Sbjct: 648 LFTVSNAFQGMFIFLFLCVLSRKIQEEYYRLFKNV 682


>gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens]
          Length = 835

 Score =  311 bits (798), Expect = 9e-85
 Identities = 209/672 (31%), Positives = 326/672 (48%), Gaps = 90/672 (13%)

Query: 31  CPPNASCVNNT---HCTCNHGYTSGSGQKLFTFPLET-CNDINECTPPYSVYCGFNAVCY 86
           C  +  C+NN     C C  G+    G      P  T C D++EC+      C  + VC+
Sbjct: 171 CHSSTHCLNNVGSYQCRCRPGWQPIPGSP--NGPNNTVCEDVDECSSGQH-QCDSSTVCF 227

Query: 87  NVEGSFYCQCVPGYRLHSGNEQFSNSNENTCQDTTSSKTTEG----RKELQKIVDKFESL 142
           N  GS+ C+C PG++   G    +N  +  C+D T S  T       + L +  DK + L
Sbjct: 228 NTVGSYSCRCRPGWKPRHGIP--NNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDL 285

Query: 143 LTNQTLWRTEGRQEISSTATTILRDVESKVLET--------ALKDPEQKVLKIQ-----N 189
                     GR   +S+A   +++V   V E         AL  P + ++  Q      
Sbjct: 286 ----------GRDSKTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLE 335

Query: 190 DSVAIETQAITDN--------------CSEERKTFNLNVQMNSMDIRCSDIIQGDTQ--G 233
           D + I  +++                   +ER   N+ +  +S  ++ +  +    +  G
Sbjct: 336 DIMRILAKSLPKGPFTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPG 395

Query: 234 PSAIAFISYSSLGNIINATFFEEMDKK----DQVYLNS----------QVVSAAIGPKRN 279
           P+    +S  ++  ++         KK    +++Y +S           V S  +     
Sbjct: 396 PAVAGILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNT 455

Query: 280 VSLSKSVTLTFQHVKMT-------PSTKKVF--------CVYWKS-TGQGSQWSRDGCFL 323
             L+  +   F H++ +       P  K V         C +WKS + +G  W+ +GC +
Sbjct: 456 KELNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQV 515

Query: 324 IHVNKSHTMCNCSHLSSFAVLMALTSQEEDPVLTVITYVGLSVSLLCLLLAALTFLLCKA 383
           +      T C CSHLSSFA+LMA     ED  LT+IT VGL++SL CLLL  LTFLL + 
Sbjct: 516 LGSKNGSTTCQCSHLSSFAILMA-HYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVRP 574

Query: 384 IRNTSTSLHLQLSLCLFLAHLLFLVGIDRTEPKV--LCSIIAGALHYLYLAAFTWMLLEG 441
           I+ + T++HL L +CLF+   +FL GI+    +V   C ++AG LHY +LAAF WM LEG
Sbjct: 575 IQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEG 634

Query: 442 VHLFLTARNLTVVNYSSINRLMKWIMFPVGYGVPAVTVAISAASWPHLYGTADRCWLHLD 501
           + L+     L V  +       +W+   +GYGVP + V +SAA +   YG    CWL  +
Sbjct: 635 LELYF----LVVRVFQGQGLSTRWLCL-IGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFE 689

Query: 502 QGFMWSFLGPVCAIFSANLVLFILVFWILKRKLSSLNSEVSTIQNTRMLAFKATAQLFIL 561
           QGF+WSFLGPV  I   N V+F+   W L +K S +N ++  ++  R L   A AQLF+L
Sbjct: 690 QGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLL 749

Query: 562 GCTWCLGLLQVGPAAQVMAYLFTIINSLQGFFIFLVYCLLSQQVQKQYQKWFREIVKSKS 621
           GCTW  GL      + V+ Y+FTI+N LQG F++L++CLL+++V+++Y+KW   +     
Sbjct: 750 GCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWACLVAGGSK 809

Query: 622 ESETYTLSSKMG 633
            SE  + +S  G
Sbjct: 810 YSEFTSTTSGTG 821



 Score =  114 bits (285), Expect = 3e-25
 Identities = 55/109 (50%), Positives = 69/109 (63%), Gaps = 2/109 (1%)

Query: 11  CFLLSLFGAVTQKTKTSCAKCPPNASCVNNTHCTCNHGYTSGSGQKLFTFPLETCNDINE 70
           C  L+L GA TQ ++     CP N+SCVN T C CN G++S S  ++ T P ETC+DINE
Sbjct: 10  CVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFS--EIITTPTETCDDINE 67

Query: 71  CTPPYSVYCGFNAVCYNVEGSFYCQCVPGYRLHSGNEQFSNSNENTCQD 119
           C  P  V CG  + C+N EGS+ C C PGY   SG + F N +ENTCQD
Sbjct: 68  CATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQD 116


>gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens]
          Length = 786

 Score =  309 bits (792), Expect = 5e-84
 Identities = 207/671 (30%), Positives = 324/671 (48%), Gaps = 93/671 (13%)

Query: 31  CPPNASCVNNTH---CTCNHGYTSGSGQKLFTFPLETCNDINECTPPYSVYCGFNAVCYN 87
           C    +CVN      C C  G+      K      + C D++EC+      C  + VC+N
Sbjct: 127 CKSYGTCVNTLGSYTCQCLPGF------KFIPEDPKVCTDVDECSSGQH-QCDSSTVCFN 179

Query: 88  VEGSFYCQCVPGYRLHSGNEQFSNSNENTCQDTTSSKTTEG----RKELQKIVDKFESLL 143
             GS+ C+C PG++   G    +N  +  C+D T S  T       + L +  DK + L 
Sbjct: 180 TVGSYSCRCRPGWKPRHGIP--NNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDL- 236

Query: 144 TNQTLWRTEGRQEISSTATTILRDVESKVLET--------ALKDPEQKVLKIQ-----ND 190
                    GR   +S+A   +++V   V E         AL  P + ++  Q      D
Sbjct: 237 ---------GRDSKTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLED 287

Query: 191 SVAIETQAITDN--------------CSEERKTFNLNVQMNSMDIRCSDIIQGDTQ--GP 234
            + I  +++                   +ER   N+ +  +S  ++ +  +    +  GP
Sbjct: 288 IMRILAKSLPKGPFTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGP 347

Query: 235 SAIAFISYSSLGNIINATFFEEMDKK----DQVYLNS----------QVVSAAIGPKRNV 280
           +    +S  ++  ++         KK    +++Y +S           V S  +      
Sbjct: 348 AVAGILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTK 407

Query: 281 SLSKSVTLTFQHVKMT-------PSTKKVF--------CVYWKS-TGQGSQWSRDGCFLI 324
            L+  +   F H++ +       P  K V         C +WKS + +G  W+ +GC ++
Sbjct: 408 ELNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVL 467

Query: 325 HVNKSHTMCNCSHLSSFAVLMALTSQEEDPVLTVITYVGLSVSLLCLLLAALTFLLCKAI 384
                 T C CSHLSSFA+LMA     ED  LT+IT VGL++SL CLLL  LTFLL + I
Sbjct: 468 GSKNGSTTCQCSHLSSFAILMA-HYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPI 526

Query: 385 RNTSTSLHLQLSLCLFLAHLLFLVGIDRTEPKV--LCSIIAGALHYLYLAAFTWMLLEGV 442
           + + T++HL L +CLF+   +FL GI+    +V   C ++AG LHY +LAAF WM LEG+
Sbjct: 527 QGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGL 586

Query: 443 HLFLTARNLTVVNYSSINRLMKWIMFPVGYGVPAVTVAISAASWPHLYGTADRCWLHLDQ 502
            L+     L V  +       +W+   +GYGVP + V +SAA +   YG    CWL  +Q
Sbjct: 587 ELYF----LVVRVFQGQGLSTRWLCL-IGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQ 641

Query: 503 GFMWSFLGPVCAIFSANLVLFILVFWILKRKLSSLNSEVSTIQNTRMLAFKATAQLFILG 562
           GF+WSFLGPV  I   N V+F+   W L +K S +N ++  ++  R L   A AQLF+LG
Sbjct: 642 GFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLG 701

Query: 563 CTWCLGLLQVGPAAQVMAYLFTIINSLQGFFIFLVYCLLSQQVQKQYQKWFREIVKSKSE 622
           CTW  GL      + V+ Y+FTI+N LQG F++L++CLL+++V+++Y+KW   +      
Sbjct: 702 CTWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWACLVAGGSKY 761

Query: 623 SETYTLSSKMG 633
           SE  + +S  G
Sbjct: 762 SEFTSTTSGTG 772



 Score =  114 bits (285), Expect = 3e-25
 Identities = 55/109 (50%), Positives = 69/109 (63%), Gaps = 2/109 (1%)

Query: 11  CFLLSLFGAVTQKTKTSCAKCPPNASCVNNTHCTCNHGYTSGSGQKLFTFPLETCNDINE 70
           C  L+L GA TQ ++     CP N+SCVN T C CN G++S S  ++ T P ETC+DINE
Sbjct: 10  CVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFS--EIITTPTETCDDINE 67

Query: 71  CTPPYSVYCGFNAVCYNVEGSFYCQCVPGYRLHSGNEQFSNSNENTCQD 119
           C  P  V CG  + C+N EGS+ C C PGY   SG + F N +ENTCQD
Sbjct: 68  CATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQD 116


>gi|163792198 latrophilin 3 precursor [Homo sapiens]
          Length = 1469

 Score =  285 bits (729), Expect = 9e-77
 Identities = 180/538 (33%), Positives = 280/538 (52%), Gaps = 34/538 (6%)

Query: 129  RKELQKIVDKFESLLTNQTL--WRTEGRQEISSTATTILRDVESKVLETALKDPEQKVLK 186
            R  +Q +V+   +LL  Q L  WR     +    AT +L  VE      A    +  +++
Sbjct: 632  RAYVQAMVETVNNLLQPQALNAWRDLTTSDQLRAATMLLHTVEESAFVLADNLLKTDIVR 691

Query: 187  IQNDSVAIETQAITDNCSEERKTFNLNVQMNS-MDIRCSDIIQGDTQGPSAIAFISYSSL 245
               D++ +E   ++   + E   F  N+   S + +  + + Q    G   +AF+ Y++L
Sbjct: 692  ENTDNIKLEVARLSTEGNLEDLKFPENMGHGSTIQLSANTLKQNGRNGEIRVAFVLYNNL 751

Query: 246  GNII---NATF---FEEMDKKDQVYLNSQVVSAAIGPK--RNVSLSKSVTLTFQHVKMTP 297
            G  +   NA+     E +     V +NS V++AAI  +    V L+  V  T +H+K + 
Sbjct: 752  GPYLSTENASMKLGTEALSTNHSVIVNSPVITAAINKEFSNKVYLADPVVFTVKHIKQSE 811

Query: 298  STKKVFCVYW---KSTGQGSQWSRDGCFLIHVNKSHTMCNCSHLSSFAVLMALTSQEE-- 352
                  C +W   K T  G  WS  GC L+  NK+HT C+C+HL++FAVLMA    +   
Sbjct: 812  ENFNPNCSFWSYSKRTMTG-YWSTQGCRLLTTNKTHTTCSCNHLTNFAVLMAHVEVKHSD 870

Query: 353  ---DPVLTVITYVGLSVSLLCLLLAALTFLLCKAIRNTSTSLHLQLSLCLFLAHLLFLVG 409
               D +L VIT+VG+ +SL+CLL+   TF   + +++   ++H  L + LF+A LLFL+G
Sbjct: 871  AVHDLLLDVITWVGILLSLVCLLICIFTFCFFRGLQSDRNTIHKNLCISLFVAELLFLIG 930

Query: 410  IDRTEPKVLCSIIAGALHYLYLAAFTWMLLEGVHLFLTARNLTVVNYSSINRLMKWIMFP 469
            I+RT+  + C++ A  LH+ +LAAFTWM LEGV L++    + V  + S +   K+  + 
Sbjct: 931  INRTDQPIACAVFAALLHFFFLAAFTWMFLEGVQLYI----MLVEVFESEHSRRKY-FYL 985

Query: 470  VGYGVPAVTVAISAASWPHLYGTADRCWLHLDQGFMWSFLGPVCAIFSANLVLFILVFWI 529
            VGYG+PA+ VA+SAA     YGT   CWL LD  F+WSF+GP   I   N++   +  + 
Sbjct: 986  VGYGMPALIVAVSAAVDYRSYGTDKVCWLRLDTYFIWSFIGPATLIIMLNVIFLGIALYK 1045

Query: 530  LKRKLSSLNSEVSTIQN---------TRMLAFKATAQLFILGCTWCLGLLQVGPAAQVMA 580
            +    + L  E   + N          +     A A L +LG TW  GL+ +  +  +MA
Sbjct: 1046 MFHHTAILKPESGCLDNINYEDNRPFIKSWVIGAIALLCLLGLTWAFGLMYINESTVIMA 1105

Query: 581  YLFTIINSLQGFFIFLVYCLLSQQVQKQYQKWFREIVKSKSESETYTLSSKMGPDSKP 638
            YLFTI NSLQG FIF+ +C+L ++V+K+Y K  R    S   +E+   S K      P
Sbjct: 1106 YLFTIFNSLQGMFIFIFHCVLQKKVRKEYGKCLRTHCCSGKSTESSIGSGKTSGSRTP 1163


>gi|6912464 latrophilin 2 precursor [Homo sapiens]
          Length = 1403

 Score =  279 bits (714), Expect = 5e-75
 Identities = 170/511 (33%), Positives = 266/511 (52%), Gaps = 24/511 (4%)

Query: 122  SSKTTEGRKELQKIVDKFESLLTNQTL--WRTEGRQEISSTATTILRDVESKVLETALKD 179
            S K + GR   + IVD  ++LL  + L  W+     E + TAT +L  +E      A   
Sbjct: 583  SEKDSAGRSYNKAIVDTVDNLLRPEALESWKHMNSSEQAHTATMLLDTLEEGAFVLADNL 642

Query: 180  PEQKVLKIQNDSVAIETQAITDNCSEERKTFNLNVQM--NSMDIRCSDIIQGDTQGPSAI 237
             E   + +  +++ +E   ++     +   F L ++   +S+ +  + + Q    G + +
Sbjct: 643  LEPTRVSMPTENIVLEVAVLSTEGQIQDFKFPLGIKGAGSSIQLSANTVKQNSRNGLAKL 702

Query: 238  AFISYSSLGNII---NATFFEEMD---KKDQVYLNSQVVSAAIGPKRN-VSLSKSVTLTF 290
             FI Y SLG  +   NAT     D   +   + +NS V+S +I  + + V L+  V  T 
Sbjct: 703  VFIIYRSLGQFLSTENATIKLGADFIGRNSTIAVNSHVISVSINKESSRVYLTDPVLFTL 762

Query: 291  QHVKMTPSTKKVFCVYWKSTGQGSQ--WSRDGCFLIHVNKSHTMCNCSHLSSFAVLMA-- 346
             H+    +     C +W  + +     WS  GC L+  NK+ T C CSHL++FA+LMA  
Sbjct: 763  PHID-PDNYFNANCSFWNYSERTMMGYWSTQGCKLVDTNKTRTTCACSHLTNFAILMAHR 821

Query: 347  ---LTSQEEDPVLTVITYVGLSVSLLCLLLAALTFLLCKAIRNTSTSLHLQLSLCLFLAH 403
                     + +LTVIT+VG+ +SL+CL +   TF   + +++   ++H  L + LF+A 
Sbjct: 822  EIAYKDGVHELLLTVITWVGIVISLVCLAICIFTFCFFRGLQSDRNTIHKNLCINLFIAE 881

Query: 404  LLFLVGIDRTEPKVLCSIIAGALHYLYLAAFTWMLLEGVHLFLTARNLTVVNYSSINRLM 463
             +FL+GID+T+  + C I AG LH+ +LAAF WM LEGV L+L    +    YS      
Sbjct: 882  FIFLIGIDKTKYAIACPIFAGLLHFFFLAAFAWMCLEGVQLYLMLVEVFESEYSR----- 936

Query: 464  KWIMFPVGYGVPAVTVAISAASWPHLYGTADRCWLHLDQGFMWSFLGPVCAIFSANLVLF 523
            K   +  GY  PA  V +SAA     YGT   CWLH+D  F+WSF+GPV  I   N++  
Sbjct: 937  KKYYYVAGYLFPATVVGVSAAIDYKSYGTEKACWLHVDNYFIWSFIGPVTFIILLNIIFL 996

Query: 524  ILVFWILKRKLSSLNSEVSTIQNTRMLAFKATAQLFILGCTWCLGLLQVGPAAQVMAYLF 583
            ++    + +  ++L  + S ++N +     A A L +LG TW  GLL +     VMAYLF
Sbjct: 997  VITLCKMVKHSNTLKPDSSRLENIKSWVLGAFALLCLLGLTWSFGLLFINEETIVMAYLF 1056

Query: 584  TIINSLQGFFIFLVYCLLSQQVQKQYQKWFR 614
            TI N+ QG FIF+ +C L ++V+K+Y K FR
Sbjct: 1057 TIFNAFQGVFIFIFHCALQKKVRKEYGKCFR 1087


>gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]
          Length = 1474

 Score =  272 bits (696), Expect = 6e-73
 Identities = 176/524 (33%), Positives = 264/524 (50%), Gaps = 37/524 (7%)

Query: 111  NSNENTCQDTTSSKTTEGRKELQKIVDKFESLLTNQTL--WRTEGRQEISSTATTILRDV 168
            +  E TC+D            ++ +V+  ++LL  + L  W+     E   TAT +L  +
Sbjct: 607  HKRERTCKDY-----------IKAVVETVDNLLRPEALESWKDMNATEQVHTATMLLDVL 655

Query: 169  ESKVLETALKDPEQKVLKIQNDSVAIETQAITDNCSEERKTFNLNV--QMNSMDIRCSDI 226
            E      A    E        ++V +E   +      +   F      + NS+ +    I
Sbjct: 656  EEGAFLLADNVREPARFLAAKENVVLEVTVLNTEGQVQELVFPQEEYPRKNSIQLSAKTI 715

Query: 227  IQGDTQGPSAIAFISYSSLGNII---NATFFEEMDKKD------QVYLNSQVVSAAIGPK 277
             Q    G   + FI Y++LG  +   NAT     +          + +NSQV++A+I  +
Sbjct: 716  KQNSRNGVVKVVFILYNNLGLFLSTENATVKLAGEAGPGGPGGASLVVNSQVIAASINKE 775

Query: 278  RN-VSLSKSVTLTFQHVKMTPSTKKVFCVYWKSTGQG--SQWSRDGCFLIHVNKSHTMCN 334
             + V L   V  T  H++   +     C +W  + +     WS  GC L+  NK+HT C 
Sbjct: 776  SSRVFLMDPVIFTVAHLE-DKNHFNANCSFWNYSERSMLGYWSTQGCRLVESNKTHTTCA 834

Query: 335  CSHLSSFAVLMA----LTSQEEDPVLTVITYVGLSVSLLCLLLAALTFLLCKAIRNTSTS 390
            CSHL++FAVLMA       +  + +L+VIT+VG+ +SL+CL +   TF   + ++    +
Sbjct: 835  CSHLTNFAVLMAHREIYQGRINELLLSVITWVGIVISLVCLAICISTFCFLRGLQTDRNT 894

Query: 391  LHLQLSLCLFLAHLLFLVGIDRTEPKVLCSIIAGALHYLYLAAFTWMLLEGVHLFLTARN 450
            +H  L + LFLA LLFLVGID+T+ ++ C I AG LHY +LAAF+W+ LEGVHL+L    
Sbjct: 895  IHKNLCINLFLAELLFLVGIDKTQYEIACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLVE 954

Query: 451  LTVVNYSSINRLMKWIMFPVGYGVPAVTVAISAASWPHLYGTADRCWLHLDQGFMWSFLG 510
            +    YS          +  GY  PA+ V I+AA     YGT   CWL +D  F+WSF+G
Sbjct: 955  VFESEYSRTK-----YYYLGGYCFPALVVGIAAAIDYRSYGTEKACWLRVDNYFIWSFIG 1009

Query: 511  PVCAIFSANLVLFILVFWILKRKLSSLNSEVSTIQNTRMLAFKATAQLFILGCTWCLGLL 570
            PV  +   NLV  ++    + R  S L  + S + N +  A  A A LF+LG TW  GLL
Sbjct: 1010 PVSFVIVVNLVFLMVTLHKMIRSSSVLKPDSSRLDNIKSWALGAIALLFLLGLTWAFGLL 1069

Query: 571  QVGPAAQVMAYLFTIINSLQGFFIFLVYCLLSQQVQKQYQKWFR 614
             +   + VMAYLFT  N+ QG FIF+ +C L ++V K+Y K  R
Sbjct: 1070 FINKESVVMAYLFTTFNAFQGVFIFVFHCALQKKVHKEYSKCLR 1113


>gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]
          Length = 1469

 Score =  272 bits (696), Expect = 6e-73
 Identities = 176/524 (33%), Positives = 264/524 (50%), Gaps = 37/524 (7%)

Query: 111  NSNENTCQDTTSSKTTEGRKELQKIVDKFESLLTNQTL--WRTEGRQEISSTATTILRDV 168
            +  E TC+D            ++ +V+  ++LL  + L  W+     E   TAT +L  +
Sbjct: 602  HKRERTCKDY-----------IKAVVETVDNLLRPEALESWKDMNATEQVHTATMLLDVL 650

Query: 169  ESKVLETALKDPEQKVLKIQNDSVAIETQAITDNCSEERKTFNLNV--QMNSMDIRCSDI 226
            E      A    E        ++V +E   +      +   F      + NS+ +    I
Sbjct: 651  EEGAFLLADNVREPARFLAAKENVVLEVTVLNTEGQVQELVFPQEEYPRKNSIQLSAKTI 710

Query: 227  IQGDTQGPSAIAFISYSSLGNII---NATFFEEMDKKD------QVYLNSQVVSAAIGPK 277
             Q    G   + FI Y++LG  +   NAT     +          + +NSQV++A+I  +
Sbjct: 711  KQNSRNGVVKVVFILYNNLGLFLSTENATVKLAGEAGPGGPGGASLVVNSQVIAASINKE 770

Query: 278  RN-VSLSKSVTLTFQHVKMTPSTKKVFCVYWKSTGQG--SQWSRDGCFLIHVNKSHTMCN 334
             + V L   V  T  H++   +     C +W  + +     WS  GC L+  NK+HT C 
Sbjct: 771  SSRVFLMDPVIFTVAHLE-DKNHFNANCSFWNYSERSMLGYWSTQGCRLVESNKTHTTCA 829

Query: 335  CSHLSSFAVLMA----LTSQEEDPVLTVITYVGLSVSLLCLLLAALTFLLCKAIRNTSTS 390
            CSHL++FAVLMA       +  + +L+VIT+VG+ +SL+CL +   TF   + ++    +
Sbjct: 830  CSHLTNFAVLMAHREIYQGRINELLLSVITWVGIVISLVCLAICISTFCFLRGLQTDRNT 889

Query: 391  LHLQLSLCLFLAHLLFLVGIDRTEPKVLCSIIAGALHYLYLAAFTWMLLEGVHLFLTARN 450
            +H  L + LFLA LLFLVGID+T+ ++ C I AG LHY +LAAF+W+ LEGVHL+L    
Sbjct: 890  IHKNLCINLFLAELLFLVGIDKTQYEIACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLVE 949

Query: 451  LTVVNYSSINRLMKWIMFPVGYGVPAVTVAISAASWPHLYGTADRCWLHLDQGFMWSFLG 510
            +    YS          +  GY  PA+ V I+AA     YGT   CWL +D  F+WSF+G
Sbjct: 950  VFESEYSRTK-----YYYLGGYCFPALVVGIAAAIDYRSYGTEKACWLRVDNYFIWSFIG 1004

Query: 511  PVCAIFSANLVLFILVFWILKRKLSSLNSEVSTIQNTRMLAFKATAQLFILGCTWCLGLL 570
            PV  +   NLV  ++    + R  S L  + S + N +  A  A A LF+LG TW  GLL
Sbjct: 1005 PVSFVIVVNLVFLMVTLHKMIRSSSVLKPDSSRLDNIKSWALGAIALLFLLGLTWAFGLL 1064

Query: 571  QVGPAAQVMAYLFTIINSLQGFFIFLVYCLLSQQVQKQYQKWFR 614
             +   + VMAYLFT  N+ QG FIF+ +C L ++V K+Y K  R
Sbjct: 1065 FINKESVVMAYLFTTFNAFQGVFIFVFHCALQKKVHKEYSKCLR 1108


>gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo
            sapiens]
          Length = 3014

 Score =  208 bits (530), Expect = 1e-53
 Identities = 129/392 (32%), Positives = 210/392 (53%), Gaps = 26/392 (6%)

Query: 230  DTQGPSAIAF-ISYSSLGNIINATFFEEMDKKD-----QVYLNSQVVSAAI---GPKRNV 280
            D  G  A+A  I Y +LG ++   +  + D++      +  +N+ +VS  +   G     
Sbjct: 2331 DDAGQFAVALVIIYRTLGQLLPERY--DPDRRSLRLPHRPIINTPMVSTLVYSEGAPLPR 2388

Query: 281  SLSKSVTLTFQHVKMTPSTKKVFCVYWK---STGQGSQWSRDGCFLIHVNKSHTMCNCSH 337
             L + V + F  +++   TK V CV+W    + G    WS  GC L+  N++H  C CSH
Sbjct: 2389 PLERPVLVEFALLEVEERTKPV-CVFWNHSLAVGGTGGWSARGCELLSRNRTHVACQCSH 2447

Query: 338  LSSFAVLMALTSQEEDPVLT--VITYVGLSVSLLCLLLAALTFLLCKAIRNTSTSLHLQL 395
             +SFAVLM ++ +E   VL   ++TY  +S+SL  LL+A +   L + +R+   S+H  L
Sbjct: 2448 TASFAVLMDISRRENGEVLPLKIVTYAAVSLSLAALLVAFVLLSLVRMLRSNLHSIHKHL 2507

Query: 396  SLCLFLAHLLFLVGIDRTEPKVLCSIIAGALHYLYLAAFTWMLLEGVHLFLTARNLTVVN 455
            ++ LFL+ L+F++GI++TE   LC+++A  LHY+Y++ F W L+E +H++   R LT V 
Sbjct: 2508 AVALFLSQLVFVIGINQTENPFLCTVVAILLHYIYMSTFAWTLVESLHVY---RMLTEVR 2564

Query: 456  YSSINRLMKWIMFPVGYGVPAVTVAISAASWPHLYGTADRCWLHLDQGFMWSFLGPVCAI 515
              +I+       + VG+G+PA+   ++    P  YG  D CWL L    +WSF GP+ A+
Sbjct: 2565 --NIDTGPMRFYYVVGWGIPAIVTGLAVGLDPQGYGNPDFCWLSLQDTLIWSFAGPIGAV 2622

Query: 516  FSANLVLFILVFWILKRKLSSLNSEVSTIQNTRMLAFKATAQLFILGCTWCLGLLQVGPA 575
               N V  +L   +  ++      +   +   R     A   L ++  TW LGLL V   
Sbjct: 2623 IIINTVTSVLSAKVSCQRKHHYYGKKGIVSLLR----TAFLLLLLISATWLLGLLAVNRD 2678

Query: 576  AQVMAYLFTIINSLQGFFIFLVYCLLSQQVQK 607
            A    YLF I + LQG F+ L +C+L+Q+V+K
Sbjct: 2679 ALSFHYLFAIFSGLQGPFVLLFHCVLNQEVRK 2710



 Score = 30.4 bits (67), Expect = 5.3
 Identities = 17/59 (28%), Positives = 25/59 (42%), Gaps = 13/59 (22%)

Query: 38   VNNTHCTCNHGYTSGSGQKLFTFPLETCNDINECTPPYSVYCGFNAVCYNVEGSFYCQC 96
            +N   C C  G+T    +           +I+ C   YS  CG N  C + EG + C+C
Sbjct: 1344 INGLRCRCPPGFTGDYCE----------TEIDLC---YSDPCGANGRCRSREGGYTCEC 1389


>gi|45433552 G protein-coupled receptor 133 [Homo sapiens]
          Length = 874

 Score =  198 bits (504), Expect = 1e-50
 Identities = 129/406 (31%), Positives = 213/406 (52%), Gaps = 37/406 (9%)

Query: 263 VYLNSQVVSAAIGP----KRNVSLSKSVTLTF-------QHVKMTPSTKKVF--CVYWKS 309
           ++  S ++S  + P     +N+S S  +T+         QH + T S+ +VF  C +   
Sbjct: 456 LFATSHLISLEVSPPPTLSQNLSGSPLITVHLKHRLTRKQHSEATNSSNRVFVYCAFLDF 515

Query: 310 TGQGSQWSRDGCFLIHVNKSHTMCNCSHLSSFAVLMALTSQE----EDPVLTVITYVGLS 365
           +     WS  GC L   N ++++C C+HL++FA+LM +   E        L+ I+YVG S
Sbjct: 516 SSGEGVWSNHGCALTRGNLTYSVCRCTHLTNFAILMQVVPLELARGHQVALSSISYVGCS 575

Query: 366 VSLLCLLLAALTFLLCKA---IRNTSTSLHLQLSLCLFLAHLLFLVGIDRTEPKVL-CSI 421
           +S+LCL+   +TF +  +   IRN    +H  LS  + +A +L L+   R EP    C +
Sbjct: 576 LSVLCLVATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVLLLISF-RLEPGTTPCQV 634

Query: 422 IAGALHYLYLAAFTWMLLEGVHLFLTARNLTVVNYSSINRLMKWIMFPVGYGVPAVTVAI 481
           +A  LHY +L+AF WML+EG+HL+    ++ +  + S +   ++  + +G+G P +   I
Sbjct: 635 MAVLLHYFFLSAFAWMLVEGLHLY----SMVIKVFGSEDSKHRY-YYGMGWGFPLLICII 689

Query: 482 SAASWPHLYGTADRCWLHLDQGFMWSFLGPVCAIFSANLVLFILVFWILKRKLSSLNSEV 541
           S +     YGT++ CWL L  G +W+F+ P   +   N+ + I V  ++  ++S+ N ++
Sbjct: 690 SLSFAMDSYGTSNNCWLSLASGAIWAFVAPALFVIVVNIGILIAVTRVIS-QISADNYKI 748

Query: 542 STIQNTRMLAFKATAQLF-ILGCTWCLGLLQVGPAAQVMAYLFTIINSLQGFFIFLVYCL 600
               +   L  KA A L  ILG +W  G+L V   A V  Y+F  +NSLQG FIFL +CL
Sbjct: 749 HGDPSAFKLTAKAVAVLLPILGTSWVFGVLAVNGCAVVFQYMFATLNSLQGLFIFLFHCL 808

Query: 601 LSQQVQKQYQKWFREIVKSKSESETYTLSSKMGPDSKPSEGDVFPG 646
           L+ +V        R   K K++  + T SS    ++KP   D+  G
Sbjct: 809 LNSEV--------RAAFKHKTKVWSLTSSSARTSNAKPFHSDLMNG 846


>gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo
            sapiens]
          Length = 2923

 Score =  197 bits (502), Expect = 2e-50
 Identities = 131/394 (33%), Positives = 205/394 (52%), Gaps = 33/394 (8%)

Query: 231  TQGPSAIAFISYSSLGNIINATFFEEMDKKD-----QVYLNSQVVSAAIGPKRNV---SL 282
            +QG +  + I Y +L  ++   +  + DK+      +  +N+ VVS ++     +   +L
Sbjct: 2241 SQGEAVASVIIYRTLAGLLPHNY--DPDKRSLRVPKRPIINTPVVSISVHDDEELLPRAL 2298

Query: 283  SKSVTLTFQHVKMTPSTKKVFCVYWKST----GQGSQWSRDGCFLIHVNKSHTMCNCSHL 338
             K VT+ F+ ++    TK + CV+W  +    G G  WS  GC ++  N+SH  C C+H+
Sbjct: 2299 DKPVTVQFRLLETEERTKPI-CVFWNHSILVSGTGG-WSARGCEVVFRNESHVSCQCNHM 2356

Query: 339  SSFAVLMALTSQEEDPVLTV--ITYVGLSVSLLCLLLAALTFLLCKAIRNTSTSLHLQLS 396
            +SFAVLM ++ +E   +L +  +TYV L V+L  LLL      L + +R+    +   L+
Sbjct: 2357 TSFAVLMDVSRRENGEILPLKTLTYVALGVTLAALLLTFFFLTLLRILRSNQHGIRRNLT 2416

Query: 397  LCLFLAHLLFLVGIDRTEPKVLCSIIAGALHYLYLAAFTWMLLEGVHLFLTARNLTVVNY 456
              L LA L+FL+GI++ +    C++IA  LH+LYL  F+W LLE +HL+   R LT V  
Sbjct: 2417 AALGLAQLVFLLGINQADLPFACTVIAILLHFLYLCTFSWALLEALHLY---RALTEVR- 2472

Query: 457  SSINRLMKWIMFPVGYGVPAVTVAISAASWPHLYGTADRCWLHLDQGFMWSFLGPVCAIF 516
              +N       + +G+GVPA    ++    P  YG  D CWL +    +WSF GPV    
Sbjct: 2473 -DVNTGPMRFYYMLGWGVPAFITGLAVGLDPEGYGNPDFCWLSIYDTLIWSFAGPVAFAV 2531

Query: 517  SANLVLFIL---VFWILKRKLSSLNSEVSTIQNTRMLAFKATAQLFILGCTWCLGLLQVG 573
            S ++ L+IL        +R+       VS +Q        + A L +L  TW L LL V 
Sbjct: 2532 SMSVFLYILAARASCAAQRQGFEKKGPVSGLQ-------PSFAVLLLLSATWLLALLSVN 2584

Query: 574  PAAQVMAYLFTIINSLQGFFIFLVYCLLSQQVQK 607
                +  YLF   N +QG FIFL Y +LS++V+K
Sbjct: 2585 SDTLLFHYLFATCNCIQGPFIFLSYVVLSKEVRK 2618


>gi|59710093 G-protein coupled receptor 112 [Homo sapiens]
          Length = 3080

 Score =  186 bits (472), Expect = 6e-47
 Identities = 126/366 (34%), Positives = 188/366 (51%), Gaps = 32/366 (8%)

Query: 265  LNSQVVSAAIGPKRNV-SLSKSVTLTFQHVKMTPSTKKVFCVYW---KSTGQGSQWSRDG 320
            L + VVSA+I     + +L+  V +T QH+    +  +V C +W    + G G  W+  G
Sbjct: 2645 LTTYVVSASISDDMFIQNLADPVVITLQHIGGNQNYGQVHCAFWDFENNNGLGG-WNSSG 2703

Query: 321  CFLIHVNKSHTMCNCSHLSSFAVLMALTSQEEDPV----LTVITYVGLSVSLLCLLLAAL 376
            C +   N ++T+C C HL+ F VLM L+    D V    L +ITY G  +S + L +A +
Sbjct: 2704 CKVKETNVNYTICQCDHLTHFGVLMDLSRSTVDSVNEQILALITYTGCGISSIFLGVAVV 2763

Query: 377  TFLLCKAIRNT-STSLHLQLSLCLFLAHLLFLVG--IDRTEPKVLCSIIAGALHYLYLAA 433
            T++    +R      + + L   L + +L+FL+   +   +   +C   A ALHY  L +
Sbjct: 2764 TYIAFHKLRKDYPAKILINLCTALLMLNLVFLINSWLSSFQKVGVCITAAVALHYFLLVS 2823

Query: 434  FTWMLLEGVHLFLTARNLTVVNYSSINRLMKWIMFPVGYGVPAVTVAISAASWPHLYGTA 493
            FTWM LE VH++L    + V N    N ++K+ +  VG+G+PA+ VAI+ +    LYGT 
Sbjct: 2824 FTWMGLEAVHMYLAL--VKVFNIYIPNYILKFCL--VGWGIPAIMVAITVSVKKDLYGTL 2879

Query: 494  DR----CWLHLDQGFMWSFLGPVCAIFSANLVLFILVFWILKRKLSSLNSEVSTIQNTR- 548
                  CW+  D  F  S +   C IF  NL +F  V       L  LNS  S IQ TR 
Sbjct: 2880 SPTTPFCWIKDDSIFYISVVAYFCLIFLMNLSMFCTV-------LVQLNSVKSQIQKTRR 2932

Query: 549  ---MLAFKATAQL-FILGCTWCLGLLQVGPAAQVMAYLFTIINSLQGFFIFLVYCLLSQQ 604
               +   K T  L F+LG TW       GP      YLF I N+LQGFFIF+ +C++ + 
Sbjct: 2933 KMILHDLKGTMSLTFLLGLTWGFAFFAWGPMRNFFLYLFAIFNTLQGFFIFVFHCVMKES 2992

Query: 605  VQKQYQ 610
            V++Q+Q
Sbjct: 2993 VREQWQ 2998


>gi|119943125 G protein-coupled receptor 64 isoform 3 [Homo sapiens]
          Length = 995

 Score =  182 bits (463), Expect = 6e-46
 Identities = 126/376 (33%), Positives = 198/376 (52%), Gaps = 33/376 (8%)

Query: 261 DQVYLNSQVVSAAIGPKRNVSLSKSVTLTFQHVKMTPSTKKVFCVYW---KSTGQGSQWS 317
           + + L S V+S+++      +L+++VT+T +H+  +     V CV+W   ++ G+G  WS
Sbjct: 505 ENLSLISYVISSSVANLTVRNLTRNVTVTLKHINPSQDELTVRCVFWDLGRNGGRGG-WS 563

Query: 318 RDGCFLIHVNKSHTMCNCSHLSSFAVLMALTSQEEDPV----LTVITYVGLSVSLLCLLL 373
            +GC +     + T+C CSHL+SF VL+ L+     P     LT ITY+G  +S + L +
Sbjct: 564 DNGCSVKDRRLNETICTCSHLTSFGVLLDLSRTSVLPAQMMALTFITYIGCGLSSIFLSV 623

Query: 374 AALTFLLCKAIRNTSTS-LHLQLSLCLFLAHLLFLVG--IDRTEPKVLCSIIAGALHYLY 430
             +T++  + IR    S + +QL   L L +L+FL+   I   + + LC  +A  LHY  
Sbjct: 624 TLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFLLDSWIALYKMQGLCISVAVFLHYFL 683

Query: 431 LAAFTWMLLEGVHLFLTARNLTVVNYSSINRLMKWIMFPVGYGVPAVTVAISAASWPHLY 490
           L +FTWM LE  H++L    + V N      ++K+ +  VG+GVPAV V I     P  Y
Sbjct: 684 LVSFTWMGLEAFHMYLAL--VKVFNTYIRKYILKFCI--VGWGVPAVVVTIILTISPDNY 739

Query: 491 GTA-----------DRCWLHLDQGFMWSFLGPVCAIFSANLVLFILVFWILKR--KLSSL 537
           G             D CW++ +  F  + +G  C IF  N+ +FI+V   L R  K   L
Sbjct: 740 GLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCVIFLLNVSMFIVVLVQLCRIKKKKQL 799

Query: 538 NSEVST-IQNTRMLAFKATAQLFILGCTWCLGLLQVGPAAQVMAYLFTIINSLQGFFIFL 596
            ++  T IQ+ R +A       F+LG TW       GP      YLF I N+LQGFFIF+
Sbjct: 800 GAQRKTSIQDLRSIA----GLTFLLGITWGFAFFAWGPVNVTFMYLFAIFNTLQGFFIFI 855

Query: 597 VYCLLSQQVQKQYQKW 612
            YC+  + V+KQ++++
Sbjct: 856 FYCVAKENVRKQWRRY 871


>gi|119943116 G protein-coupled receptor 64 isoform 2 [Homo sapiens]
          Length = 1003

 Score =  182 bits (463), Expect = 6e-46
 Identities = 126/376 (33%), Positives = 198/376 (52%), Gaps = 33/376 (8%)

Query: 261 DQVYLNSQVVSAAIGPKRNVSLSKSVTLTFQHVKMTPSTKKVFCVYW---KSTGQGSQWS 317
           + + L S V+S+++      +L+++VT+T +H+  +     V CV+W   ++ G+G  WS
Sbjct: 513 ENLSLISYVISSSVANLTVRNLTRNVTVTLKHINPSQDELTVRCVFWDLGRNGGRGG-WS 571

Query: 318 RDGCFLIHVNKSHTMCNCSHLSSFAVLMALTSQEEDPV----LTVITYVGLSVSLLCLLL 373
            +GC +     + T+C CSHL+SF VL+ L+     P     LT ITY+G  +S + L +
Sbjct: 572 DNGCSVKDRRLNETICTCSHLTSFGVLLDLSRTSVLPAQMMALTFITYIGCGLSSIFLSV 631

Query: 374 AALTFLLCKAIRNTSTS-LHLQLSLCLFLAHLLFLVG--IDRTEPKVLCSIIAGALHYLY 430
             +T++  + IR    S + +QL   L L +L+FL+   I   + + LC  +A  LHY  
Sbjct: 632 TLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFLLDSWIALYKMQGLCISVAVFLHYFL 691

Query: 431 LAAFTWMLLEGVHLFLTARNLTVVNYSSINRLMKWIMFPVGYGVPAVTVAISAASWPHLY 490
           L +FTWM LE  H++L    + V N      ++K+ +  VG+GVPAV V I     P  Y
Sbjct: 692 LVSFTWMGLEAFHMYLAL--VKVFNTYIRKYILKFCI--VGWGVPAVVVTIILTISPDNY 747

Query: 491 GTA-----------DRCWLHLDQGFMWSFLGPVCAIFSANLVLFILVFWILKR--KLSSL 537
           G             D CW++ +  F  + +G  C IF  N+ +FI+V   L R  K   L
Sbjct: 748 GLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCVIFLLNVSMFIVVLVQLCRIKKKKQL 807

Query: 538 NSEVST-IQNTRMLAFKATAQLFILGCTWCLGLLQVGPAAQVMAYLFTIINSLQGFFIFL 596
            ++  T IQ+ R +A       F+LG TW       GP      YLF I N+LQGFFIF+
Sbjct: 808 GAQRKTSIQDLRSIA----GLTFLLGITWGFAFFAWGPVNVTFMYLFAIFNTLQGFFIFI 863

Query: 597 VYCLLSQQVQKQYQKW 612
            YC+  + V+KQ++++
Sbjct: 864 FYCVAKENVRKQWRRY 879


>gi|119943120 G protein-coupled receptor 64 isoform 1 [Homo sapiens]
          Length = 1017

 Score =  182 bits (463), Expect = 6e-46
 Identities = 126/376 (33%), Positives = 198/376 (52%), Gaps = 33/376 (8%)

Query: 261 DQVYLNSQVVSAAIGPKRNVSLSKSVTLTFQHVKMTPSTKKVFCVYW---KSTGQGSQWS 317
           + + L S V+S+++      +L+++VT+T +H+  +     V CV+W   ++ G+G  WS
Sbjct: 527 ENLSLISYVISSSVANLTVRNLTRNVTVTLKHINPSQDELTVRCVFWDLGRNGGRGG-WS 585

Query: 318 RDGCFLIHVNKSHTMCNCSHLSSFAVLMALTSQEEDPV----LTVITYVGLSVSLLCLLL 373
            +GC +     + T+C CSHL+SF VL+ L+     P     LT ITY+G  +S + L +
Sbjct: 586 DNGCSVKDRRLNETICTCSHLTSFGVLLDLSRTSVLPAQMMALTFITYIGCGLSSIFLSV 645

Query: 374 AALTFLLCKAIRNTSTS-LHLQLSLCLFLAHLLFLVG--IDRTEPKVLCSIIAGALHYLY 430
             +T++  + IR    S + +QL   L L +L+FL+   I   + + LC  +A  LHY  
Sbjct: 646 TLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFLLDSWIALYKMQGLCISVAVFLHYFL 705

Query: 431 LAAFTWMLLEGVHLFLTARNLTVVNYSSINRLMKWIMFPVGYGVPAVTVAISAASWPHLY 490
           L +FTWM LE  H++L    + V N      ++K+ +  VG+GVPAV V I     P  Y
Sbjct: 706 LVSFTWMGLEAFHMYLAL--VKVFNTYIRKYILKFCI--VGWGVPAVVVTIILTISPDNY 761

Query: 491 GTA-----------DRCWLHLDQGFMWSFLGPVCAIFSANLVLFILVFWILKR--KLSSL 537
           G             D CW++ +  F  + +G  C IF  N+ +FI+V   L R  K   L
Sbjct: 762 GLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCVIFLLNVSMFIVVLVQLCRIKKKKQL 821

Query: 538 NSEVST-IQNTRMLAFKATAQLFILGCTWCLGLLQVGPAAQVMAYLFTIINSLQGFFIFL 596
            ++  T IQ+ R +A       F+LG TW       GP      YLF I N+LQGFFIF+
Sbjct: 822 GAQRKTSIQDLRSIA----GLTFLLGITWGFAFFAWGPVNVTFMYLFAIFNTLQGFFIFI 877

Query: 597 VYCLLSQQVQKQYQKW 612
            YC+  + V+KQ++++
Sbjct: 878 FYCVAKENVRKQWRRY 893


>gi|119943129 G protein-coupled receptor 64 isoform 4 [Homo sapiens]
          Length = 1014

 Score =  182 bits (463), Expect = 6e-46
 Identities = 126/376 (33%), Positives = 198/376 (52%), Gaps = 33/376 (8%)

Query: 261 DQVYLNSQVVSAAIGPKRNVSLSKSVTLTFQHVKMTPSTKKVFCVYW---KSTGQGSQWS 317
           + + L S V+S+++      +L+++VT+T +H+  +     V CV+W   ++ G+G  WS
Sbjct: 524 ENLSLISYVISSSVANLTVRNLTRNVTVTLKHINPSQDELTVRCVFWDLGRNGGRGG-WS 582

Query: 318 RDGCFLIHVNKSHTMCNCSHLSSFAVLMALTSQEEDPV----LTVITYVGLSVSLLCLLL 373
            +GC +     + T+C CSHL+SF VL+ L+     P     LT ITY+G  +S + L +
Sbjct: 583 DNGCSVKDRRLNETICTCSHLTSFGVLLDLSRTSVLPAQMMALTFITYIGCGLSSIFLSV 642

Query: 374 AALTFLLCKAIRNTSTS-LHLQLSLCLFLAHLLFLVG--IDRTEPKVLCSIIAGALHYLY 430
             +T++  + IR    S + +QL   L L +L+FL+   I   + + LC  +A  LHY  
Sbjct: 643 TLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFLLDSWIALYKMQGLCISVAVFLHYFL 702

Query: 431 LAAFTWMLLEGVHLFLTARNLTVVNYSSINRLMKWIMFPVGYGVPAVTVAISAASWPHLY 490
           L +FTWM LE  H++L    + V N      ++K+ +  VG+GVPAV V I     P  Y
Sbjct: 703 LVSFTWMGLEAFHMYLAL--VKVFNTYIRKYILKFCI--VGWGVPAVVVTIILTISPDNY 758

Query: 491 GTA-----------DRCWLHLDQGFMWSFLGPVCAIFSANLVLFILVFWILKR--KLSSL 537
           G             D CW++ +  F  + +G  C IF  N+ +FI+V   L R  K   L
Sbjct: 759 GLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCVIFLLNVSMFIVVLVQLCRIKKKKQL 818

Query: 538 NSEVST-IQNTRMLAFKATAQLFILGCTWCLGLLQVGPAAQVMAYLFTIINSLQGFFIFL 596
            ++  T IQ+ R +A       F+LG TW       GP      YLF I N+LQGFFIF+
Sbjct: 819 GAQRKTSIQDLRSIA----GLTFLLGITWGFAFFAWGPVNVTFMYLFAIFNTLQGFFIFI 874

Query: 597 VYCLLSQQVQKQYQKW 612
            YC+  + V+KQ++++
Sbjct: 875 FYCVAKENVRKQWRRY 890


>gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo
            sapiens]
          Length = 3312

 Score =  182 bits (463), Expect = 6e-46
 Identities = 120/416 (28%), Positives = 202/416 (48%), Gaps = 29/416 (6%)

Query: 233  GPSAIAFISYSSLGNIINATFFEEMDKK---DQVYLNSQVVSAAIGPKRNVS---LSKSV 286
            G S I  + Y +LG ++ A F  E           +NS VVS A+   RN     L   +
Sbjct: 2404 GISIIILLVYRTLGGLLPAQFQAERRGARLPQNPVMNSPVVSVAVFHGRNFLRGILESPI 2463

Query: 287  TLTFQHVKMTPSTKKVFCVYWKSTGQGSQ---WSRDGCFLIHVNKSHTMCNCSHLSSFAV 343
            +L F+ ++ T +  K  CV W   G   Q   W+   C L+H N SH  C CS   +F V
Sbjct: 2464 SLEFRLLQ-TANRSKAICVQWDPPGLAEQHGVWTARDCELVHRNGSHARCRCSRTGTFGV 2522

Query: 344  LMALTSQE----EDPVLTVITYVGLSVSLLCLLLAALTFLLCKAIRNTSTSLHLQLSLCL 399
            LM  + +E    +  +L V T+V ++VS+  L+L A   L  +++++    +H  ++  L
Sbjct: 2523 LMDASPRERLEGDLELLAVFTHVVVAVSVAALVLTAAILLSLRSLKSNVRGIHANVAAAL 2582

Query: 400  FLAHLLFLVGIDRTEPKVLCSIIAGALHYLYLAAFTWMLLEGVHLFLTARNLTVVNYSSI 459
             +A LLFL+GI RT  +++C+ +A  LHY +L+ F W+ ++G+HL+        V   ++
Sbjct: 2583 GVAELLFLLGIHRTHNQLVCTAVAILLHYFFLSTFAWLFVQGLHLYRMQ-----VEPRNV 2637

Query: 460  NRLMKWIMFPVGYGVPAVTVAISAASWPHLYGTADRCWLHLDQGFMWSFLGPVCAIFSAN 519
            +R        +G+GVPAV + ++    P  YG  D CW+ + +  +WSF GPV  +   N
Sbjct: 2638 DRGAMRFYHALGWGVPAVLLGLAVGLDPEGYGNPDFCWISVHEPLIWSFAGPVVLVIVMN 2697

Query: 520  LVLFILVFWILKRKLSSLNSEVSTIQNTRMLAFKATAQLFIL-GCTWCLGLLQVGPAAQV 578
              +F+L         +S ++     + T  L  +++  L +L   +W  GLL V  +   
Sbjct: 2698 GTMFLLA------ARTSCSTGQREAKKTSALTLRSSFLLLLLVSASWLFGLLAVNHSILA 2751

Query: 579  MAYLFTIINSLQGFFIFLVYCLLSQQVQKQYQKWFREIVKSKSESETYTLSSKMGP 634
              YL   +  LQG  + L++C+L+   +     W    +  K+  E    +  +GP
Sbjct: 2752 FHYLHAGLCGLQGLAVLLLFCVLNADAR---AAWMPACLGRKAAPEEARPAPGLGP 2804


>gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [Homo
            sapiens]
          Length = 1584

 Score =  155 bits (392), Expect = 1e-37
 Identities = 110/403 (27%), Positives = 198/403 (49%), Gaps = 32/403 (7%)

Query: 218  SMDIRCSDIIQGDTQGPSAIAFISYSSLGNIINATFFEEMDKKDQVYLNSQVVSAAIGPK 277
            S  +  + + + D      +  + Y +LG+ +         +++   LNS+V+S  + P 
Sbjct: 808  SKSVFSTGLTEADEASVFVVGTVLYRNLGSFLAL-------QRNTTVLNSKVISVTVKPP 860

Query: 278  RNVSLSKSVTLTFQHVKMTPSTKKVFCVYWKSTGQGSQ--------WSRDGCFLIHVNKS 329
               SL   + + F H  M   T    C+ W  T   S         WS  GC  + ++  
Sbjct: 861  PR-SLRTPLEIEFAH--MYNGTTNQTCILWDETDVPSSSAPPQLGPWSWRGCRTVPLDAL 917

Query: 330  HTMCNCSHLSSFAVLMALTSQ---EEDPVLTVITYVGLSVSLLCLLLAALTFL-LCKAIR 385
             T C C  LS+FA+L  L++    E+  + +V   VG  VS L LL+  + ++ + + IR
Sbjct: 918  RTRCLCDRLSTFAILAQLSADANMEKATLPSVTLIVGCGVSSLTLLMLVIIYVSVWRYIR 977

Query: 386  NTSTSLHLQLSLCLFLAHLLFLVGIDRTEPKVLCSIIAGALHYLYLAAFTWMLLEGVHLF 445
            +  + + +   L +  ++ L L+G  +T  KV+C+++A  LH+ +L++F W+L E    +
Sbjct: 978  SERSVILINFCLSIISSNALILIGQTQTRNKVVCTLVAAFLHFFFLSSFCWVLTEAWQSY 1037

Query: 446  LTARNLTVVNYSSINRLMKWIMFPVGYGVPAVTVAISAA-SWPHLYGTADRCWLHLDQGF 504
            +       V     NRL++     +G+G+PA+ VAIS   +    Y T + CWL L+ G 
Sbjct: 1038 M------AVTGHLRNRLIRKRFLCLGWGLPALVVAISVGFTKAKGYSTMNYCWLSLEGGL 1091

Query: 505  MWSFLGPVCAIFSANLVLFILVFWILKRKLSSLNSEVSTIQNTRMLAFKATAQLFILGCT 564
            +++F+GP  A+   N+V+ ILVF  L  K    + ++   +      + +   L +L  T
Sbjct: 1092 LYAFVGPAAAVVLVNMVIGILVFNKLVSKDGITDKKLK--ERAGASLWSSCVVLPLLALT 1149

Query: 565  WCLGLLQV-GPAAQVMAYLFTIINSLQGFFIFLVYCLLSQQVQ 606
            W   +L V    + +   LF + +SL+GF I +V+C+L ++VQ
Sbjct: 1150 WMSAVLAVTDRRSALFQILFAVFDSLEGFVIVMVHCILRREVQ 1192


>gi|240120161 G protein-coupled receptor 144 [Homo sapiens]
          Length = 963

 Score =  149 bits (375), Expect = 1e-35
 Identities = 109/366 (29%), Positives = 180/366 (49%), Gaps = 28/366 (7%)

Query: 262 QVYLNSQVVSAAIGPKR-NVSLSKSVTLTF--QHVKMTPSTKKVFCVYWKSTGQGSQWSR 318
           Q +L++QV SA I  +  +V+   +V +TF  QH   +P    +F  +  S   G  W+ 
Sbjct: 561 QRFLSTQVGSAIISSEVWDVTGEVNVAMTFHLQHRAQSP----LFPPHPPSPYTGGAWAT 616

Query: 319 DGCFLIHVNKSHTMCNCSHLSSFAVLMAL----TSQEEDPVLTVITYVGLSVSLLCLLLA 374
            GC +  +    T C C+H +SFA+L+ +       EE+ +L  +++VG  VS   L   
Sbjct: 617 TGCSVAALYLDSTACFCNHSTSFAILLQIYEVQRGPEEESLLRTLSFVGCGVSFCALTTT 676

Query: 375 ALTFLLCKAIRNTSTSLHLQLSLCLFLAHLLFLVGIDRTEPKVLCSIIAGALHYLYLAAF 434
            L FL+    ++  T++H  L+  L  A    +        +V C  +  A+H+L+L AF
Sbjct: 677 FLLFLVAGVPKSERTTVHKNLTFSLASAEGFLMTSEWAKANEVACVAVTVAMHFLFLVAF 736

Query: 435 TWMLLEGVHLFLTARNLTVVNYSSINRLMKWIMFPVGYGVPAVTVAISAASWPHLYGTAD 494
           +WML+EG+ L+   R +  V+      +   +    G+GVP   VA++ A  PH Y    
Sbjct: 737 SWMLVEGLLLW---RKVVAVSMHPGPGMR--LYHATGWGVPVGIVAVTLAMLPHDYVAPG 791

Query: 495 RCWLHLDQGFMWSFLGPVCAIFSANLVLFILVFWIL---KRKLSSLNSEVSTIQNTRMLA 551
            CWL++    +W+F+GPV  + +AN  +   V  I     R+ + + S    +Q      
Sbjct: 792 HCWLNVHTNAIWAFVGPVLFVLTANTCILARVVMITVSSARRRARMLSPQPCLQQQIWTQ 851

Query: 552 FKATAQ-----LFILGCTWCLGLL-QVGPAAQVMAYLFTIINSLQGFFIFLVYCLLSQQV 605
             AT +     L +LG TW  G+L  + PA    AY    +NS+QG +IFLVY   +++V
Sbjct: 852 IWATVKPVLVLLPVLGLTWLAGILVHLSPA---WAYAAVGLNSIQGLYIFLVYAACNEEV 908

Query: 606 QKQYQK 611
           +   Q+
Sbjct: 909 RSALQR 914


>gi|4502359 brain-specific angiogenesis inhibitor 3 [Homo sapiens]
          Length = 1522

 Score =  145 bits (365), Expect = 1e-34
 Identities = 107/408 (26%), Positives = 186/408 (45%), Gaps = 54/408 (13%)

Query: 248  IINATFFEEMDK-----KDQVYLNSQVVSAAIGPKRNVSLSKSVTLTFQHVKMTPSTKKV 302
            ++ A  ++ +D      ++   +NS+++   I P+   + S    L  +   +   T   
Sbjct: 761  VLGAVLYKNLDLILPTLRNYTVINSKIIVVTIRPEPKTTDS---FLEIELAHLANGTLNP 817

Query: 303  FCVYW---KSTGQGSQWSRDGCFLIHVNKSHTMCNCSHLSSFAVLMALTSQ---EEDPVL 356
            +CV W   K+      WS  GC  +  + SHT C C  LS+FA+L     +   E     
Sbjct: 818  YCVLWDDSKTNESLGTWSTQGCKTVLTDASHTKCLCDRLSTFAILAQQPREIIMESSGTP 877

Query: 357  TVITYVGLSVSLLCLLLAALTFL-LCKAIRNTSTSLHLQLSLCLFLAHLLFLVGIDRTEP 415
            +V   VG  +S L L+  A+ +  L + IR+  + + +   L +  +++L LVG  +T  
Sbjct: 878  SVTLIVGSGLSCLALITLAVVYAALWRYIRSERSIILINFCLSIISSNILILVGQTQTHN 937

Query: 416  KVLCSIIAGALHYLYLAAFTWMLLEGVHLFLTARNLTVVNYSSINRLMKWIMFPVGYGVP 475
            K +C+     LH+ +LA+F W+L E    ++       V      RL++     +G+G+P
Sbjct: 938  KSICTTTTAFLHFFFLASFCWVLTEAWQSYM------AVTGKIRTRLIRKRFLCLGWGLP 991

Query: 476  AVTVAISAA-SWPHLYGTADRCWLHLDQGFMWSFLGPVCAIFSANLVLFILVF------- 527
            A+ VA S   +    YGT   CWL L+ G +++F+GP  A+   N+V+ ILVF       
Sbjct: 992  ALVVATSVGFTRTKGYGTDHYCWLSLEGGLLYAFVGPAAAVVLVNMVIGILVFNKLVSRD 1051

Query: 528  WILKRKLSSLNSEVS------------------------TIQNTRMLAFKATAQLFILGC 563
             IL +KL     ++S                        T  N     + +   L +L  
Sbjct: 1052 GILDKKLKHRAGQMSEPHSGLTLKCAKCGVVSTTALSATTASNAMASLWSSCVVLPLLAL 1111

Query: 564  TWCLGLLQVGPAAQVM-AYLFTIINSLQGFFIFLVYCLLSQQVQKQYQ 610
            TW   +L +     ++   LF + +SLQGF I +V+C+L ++VQ  ++
Sbjct: 1112 TWMSAVLAMTDKRSILFQILFAVFDSLQGFVIVMVHCILRREVQDAFR 1159


>gi|74048357 G protein-coupled receptor 126 alpha 1 precursor [Homo
            sapiens]
          Length = 1221

 Score =  143 bits (361), Expect = 4e-34
 Identities = 149/548 (27%), Positives = 246/548 (44%), Gaps = 73/548 (13%)

Query: 118  QDTTSSKTTEGRKELQKIVDKFESLLTNQTLWRTEGRQEISSTATTILRDVESKVLET-- 175
            Q+ TS+  T   +++++IV+K E++  + TL  T     + +  + IL   +S +LE+  
Sbjct: 599  QNLTSANITNIVEQVKRIVNKEENI--DITLGST-----LMNIFSNILSSSDSDLLESSS 651

Query: 176  -ALKDPEQKVLKIQNDS---VAIETQAITDNCSE------ERKTFNLNVQMNSMDIRCSD 225
             ALK  ++   KI  +S   V I T+ +  + S           F++ +  N+      D
Sbjct: 652  EALKTIDELAFKIDLNSTSHVNITTRNLALSVSSLLPGTNAISNFSIGLPSNNESYFQMD 711

Query: 226  IIQGDTQGPSAIAFISYSSLGNI----------INATFFEEMDKKDQV-----YLNSQVV 270
               G    P A   +  + L N+             TFF +      V      L S V+
Sbjct: 712  FESGQVD-PLASVILPPNLLENLSPEDSVLVRRAQFTFFNKTGLFQDVGPQRKTLVSYVM 770

Query: 271  SAAIGPKRNVSLSKSVTLTFQHVKMTPSTKKVFCVYWKSTGQGS--QWSRDGCFLIH-VN 327
            + +IG     +L   V +  +H + T       C +W      S   W+  GC      +
Sbjct: 771  ACSIGNITIQNLKDPVQIKIKHTR-TQEVHHPICAFWDLNKNKSFGGWNTSGCVAHRDSD 829

Query: 328  KSHTMCNCSHLSSFAVLMALTSQEED------PVLTVITYVGLSVSLLCLLLAALTFLLC 381
             S T+C C+H + F VLM L             VLT I+Y+G  +S +      LT++  
Sbjct: 830  ASETVCLCNHFTHFGVLMDLPRSASQLDARNTKVLTFISYIGCGISAIFSAATLLTYVAF 889

Query: 382  KAIRNTSTS-LHLQLSLCLFLAHLLFLVGIDRTEPKV--LCSIIAGALHYLYLAAFTWML 438
            + +R    S + + LS  L   +LLFL+    T   V  LC  +A  LH+  LA FTWM 
Sbjct: 890  EKLRRDYPSKILMNLSTALLFLNLLFLLDGWITSFNVDGLCIAVAVLLHFFLLATFTWMG 949

Query: 439  LEGVHLFLTARNLTVVNYSSINRLMKWIMFPVGYGVPAVTVAISAASWPH--LYGTA--- 493
            LE +H+++    + V N      ++K+ +  +G+G+PA+ V++  AS  +  +YG     
Sbjct: 950  LEAIHMYIAL--VKVFNTYIRRYILKFCI--IGWGLPALVVSVVLASRNNNEVYGKESYG 1005

Query: 494  -----DRCWLHLDQGFMWSFLGPVCAIFSANLVLFILVFWIL-----KRKLSSLNSEVST 543
                 + CW+     F  +  G    +F  N+ +FI+V   +     KR   +L  EV  
Sbjct: 1006 KEKGDEFCWIQDPVIFYVTCAGYFGVMFFLNIAMFIVVMVQICGRNGKRSNRTLREEV-- 1063

Query: 544  IQNTRMLAFKATAQLFILGCTWCLGLLQVGPAAQVMAYLFTIINSLQGFFIFLVYCLLSQ 603
            ++N R +     +  F+LG TW       GP      YLF+I NSLQG FIF+ +C + +
Sbjct: 1064 LRNLRSVV----SLTFLLGMTWGFAFFAWGPLNIPFMYLFSIFNSLQGLFIFIFHCAMKE 1119

Query: 604  QVQKQYQK 611
             VQKQ+++
Sbjct: 1120 NVQKQWRR 1127


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.134    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,018,800
Number of Sequences: 37866
Number of extensions: 1003945
Number of successful extensions: 4199
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 150
Number of HSP's successfully gapped in prelim test: 97
Number of HSP's that attempted gapping in prelim test: 2955
Number of HSP's gapped (non-prelim): 907
length of query: 652
length of database: 18,247,518
effective HSP length: 109
effective length of query: 543
effective length of database: 14,120,124
effective search space: 7667227332
effective search space used: 7667227332
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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