Guide to the Human Genome
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Search of human proteins with 5174419

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5174419 caseinolytic peptidase, ATP-dependent, proteolytic
subunit precursor [Homo sapiens]
         (277 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5174419 caseinolytic peptidase, ATP-dependent, proteolytic su...   555   e-158
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]       35   0.072
gi|169160869 PREDICTED: hypothetical protein [Homo sapiens]            31   1.0  
gi|88950401 PREDICTED: hypothetical protein [Homo sapiens]             31   1.0  
gi|88942880 PREDICTED: hypothetical protein [Homo sapiens]             31   1.0  
gi|156142192 hypothetical protein LOC51306 isoform 3 [Homo sapiens]    30   2.3  
gi|156142190 hypothetical protein LOC51306 isoform 2 [Homo sapiens]    30   2.3  
gi|156142188 hypothetical protein LOC51306 isoform 1 [Homo sapiens]    30   2.3  
gi|120587023 down-regulated in metastasis [Homo sapiens]               30   3.0  
gi|89036565 PREDICTED: similar to Temporarily Assigned Gene name...    30   3.0  
gi|157388904 HEAT repeat containing 2 [Homo sapiens]                   29   5.2  
gi|13435377 glucocorticoid modulatory element binding protein 1 ...    28   6.7  
gi|13435375 glucocorticoid modulatory element binding protein 1 ...    28   6.7  
gi|226958575 RAS protein activator like 2 isoform 2 [Homo sapiens]     28   8.8  
gi|4758808 RAS protein activator like 2 isoform 1 [Homo sapiens]       28   8.8  
gi|78190495 Kv channel interacting protein 3 isoform 2 [Homo sap...    28   8.8  
gi|7305199 Kv channel interacting protein 3 isoform 1 [Homo sapi...    28   8.8  

>gi|5174419 caseinolytic peptidase, ATP-dependent, proteolytic
           subunit precursor [Homo sapiens]
          Length = 277

 Score =  555 bits (1429), Expect = e-158
 Identities = 277/277 (100%), Positives = 277/277 (100%)

Query: 1   MWPGILVGGARVASCRYPALGPRLAAHFPAQRPPQRTLQNGLALQRCLHATATRALPLIP 60
           MWPGILVGGARVASCRYPALGPRLAAHFPAQRPPQRTLQNGLALQRCLHATATRALPLIP
Sbjct: 1   MWPGILVGGARVASCRYPALGPRLAAHFPAQRPPQRTLQNGLALQRCLHATATRALPLIP 60

Query: 61  IVVEQTGRGERAYDIYSRLLRERIVCVMGPIDDSVASLVIAQLLFLQSESNKKPIHMYIN 120
           IVVEQTGRGERAYDIYSRLLRERIVCVMGPIDDSVASLVIAQLLFLQSESNKKPIHMYIN
Sbjct: 61  IVVEQTGRGERAYDIYSRLLRERIVCVMGPIDDSVASLVIAQLLFLQSESNKKPIHMYIN 120

Query: 121 SPGGVVTAGLAIYDTMQYILNPICTWCVGQAASMGSLLLAAGTPGMRHSLPNSRIMIHQP 180
           SPGGVVTAGLAIYDTMQYILNPICTWCVGQAASMGSLLLAAGTPGMRHSLPNSRIMIHQP
Sbjct: 121 SPGGVVTAGLAIYDTMQYILNPICTWCVGQAASMGSLLLAAGTPGMRHSLPNSRIMIHQP 180

Query: 181 SGGARGQATDIAIQAEEIMKLKKQLYNIYAKHTKQSLQVIESAMERDRYMSPMEAQEFGI 240
           SGGARGQATDIAIQAEEIMKLKKQLYNIYAKHTKQSLQVIESAMERDRYMSPMEAQEFGI
Sbjct: 181 SGGARGQATDIAIQAEEIMKLKKQLYNIYAKHTKQSLQVIESAMERDRYMSPMEAQEFGI 240

Query: 241 LDKVLVHPPQDGEDEPTLVQKEPVEAAPAAEPVPAST 277
           LDKVLVHPPQDGEDEPTLVQKEPVEAAPAAEPVPAST
Sbjct: 241 LDKVLVHPPQDGEDEPTLVQKEPVEAAPAAEPVPAST 277


>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
          Length = 2240

 Score = 35.0 bits (79), Expect = 0.072
 Identities = 25/104 (24%), Positives = 48/104 (46%), Gaps = 6/104 (5%)

Query: 174  RIMIHQPSGGARGQATDIAIQAEEIMK-LKKQLYNIYAKHTKQSLQVIESAMERDRYMSP 232
            R  + +P+    G AT   ++ +++++ L KQ+     +  K+ L+  E A+ + R    
Sbjct: 1454 RNSVERPAEPVAGAATPSLVEQQKMLEELNKQI-----EEQKRQLEEQEEALRQQRAAVG 1508

Query: 233  MEAQEFGILDKVLVHPPQDGEDEPTLVQKEPVEAAPAAEPVPAS 276
            +    F + D ++  PP+    +  L Q+E   A   A   PAS
Sbjct: 1509 VSMAHFSVSDALMSPPPKSSLPKAELFQQEQQSADKPASLPPAS 1552


>gi|169160869 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 120

 Score = 31.2 bits (69), Expect = 1.0
 Identities = 17/46 (36%), Positives = 27/46 (58%), Gaps = 5/46 (10%)

Query: 234 EAQEFGILDKVLVHPPQDGED----EPTLVQKEPVEAAPAAEPVPA 275
           E + F +++     PP  GE     EP L  ++P++A+P A+PVPA
Sbjct: 32  EQRSFPLVEAQAQAPPH-GEARPLAEPALSLRQPIDASPRADPVPA 76


>gi|88950401 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 120

 Score = 31.2 bits (69), Expect = 1.0
 Identities = 17/46 (36%), Positives = 27/46 (58%), Gaps = 5/46 (10%)

Query: 234 EAQEFGILDKVLVHPPQDGED----EPTLVQKEPVEAAPAAEPVPA 275
           E + F +++     PP  GE     EP L  ++P++A+P A+PVPA
Sbjct: 32  EQRSFPLVEAQAQAPPH-GEARPLAEPALSLRQPIDASPRADPVPA 76


>gi|88942880 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 120

 Score = 31.2 bits (69), Expect = 1.0
 Identities = 17/46 (36%), Positives = 27/46 (58%), Gaps = 5/46 (10%)

Query: 234 EAQEFGILDKVLVHPPQDGED----EPTLVQKEPVEAAPAAEPVPA 275
           E + F +++     PP  GE     EP L  ++P++A+P A+PVPA
Sbjct: 32  EQRSFPLVEAQAQAPPH-GEARRLAEPALSLRQPIDASPRADPVPA 76


>gi|156142192 hypothetical protein LOC51306 isoform 3 [Homo sapiens]
          Length = 791

 Score = 30.0 bits (66), Expect = 2.3
 Identities = 20/66 (30%), Positives = 32/66 (48%), Gaps = 9/66 (13%)

Query: 197 EIMKLKKQLYNIYAKHTKQSLQVIESAMERDRYMSPMEAQEFGILDKVLVHPPQDGEDEP 256
           E+ KL+KQ+ +  AKH     + +     R   +     + FG     L H  ++ EDEP
Sbjct: 516 ELTKLRKQIKD--AKHKNSDGEFVPQTRPRSNTLP----KSFG---SSLDHEDEENEDEP 566

Query: 257 TLVQKE 262
            ++QKE
Sbjct: 567 KVIQKE 572


>gi|156142190 hypothetical protein LOC51306 isoform 2 [Homo sapiens]
          Length = 887

 Score = 30.0 bits (66), Expect = 2.3
 Identities = 20/66 (30%), Positives = 32/66 (48%), Gaps = 9/66 (13%)

Query: 197 EIMKLKKQLYNIYAKHTKQSLQVIESAMERDRYMSPMEAQEFGILDKVLVHPPQDGEDEP 256
           E+ KL+KQ+ +  AKH     + +     R   +     + FG     L H  ++ EDEP
Sbjct: 612 ELTKLRKQIKD--AKHKNSDGEFVPQTRPRSNTLP----KSFG---SSLDHEDEENEDEP 662

Query: 257 TLVQKE 262
            ++QKE
Sbjct: 663 KVIQKE 668


>gi|156142188 hypothetical protein LOC51306 isoform 1 [Homo sapiens]
          Length = 915

 Score = 30.0 bits (66), Expect = 2.3
 Identities = 20/66 (30%), Positives = 32/66 (48%), Gaps = 9/66 (13%)

Query: 197 EIMKLKKQLYNIYAKHTKQSLQVIESAMERDRYMSPMEAQEFGILDKVLVHPPQDGEDEP 256
           E+ KL+KQ+ +  AKH     + +     R   +     + FG     L H  ++ EDEP
Sbjct: 612 ELTKLRKQIKD--AKHKNSDGEFVPQTRPRSNTLP----KSFG---SSLDHEDEENEDEP 662

Query: 257 TLVQKE 262
            ++QKE
Sbjct: 663 KVIQKE 668


>gi|120587023 down-regulated in metastasis [Homo sapiens]
          Length = 2785

 Score = 29.6 bits (65), Expect = 3.0
 Identities = 18/64 (28%), Positives = 33/64 (51%), Gaps = 1/64 (1%)

Query: 182  GGARGQATDIAIQAEEIMKLKKQLYNIYAKHTKQSLQVIESAMERDRYMSPMEAQEFGIL 241
            G ARGQ   + +   + + +  +    Y + T++ LQV+ +  E D Y +  +A  FG+L
Sbjct: 2170 GAARGQNFHLVVNCFKCVTILVKKVKSY-QITEKQLQVLLAYAEEDIYDTSRQATAFGLL 2228

Query: 242  DKVL 245
              +L
Sbjct: 2229 KAIL 2232


>gi|89036565 PREDICTED: similar to Temporarily Assigned Gene name
            family member (tag-184) [Homo sapiens]
          Length = 2785

 Score = 29.6 bits (65), Expect = 3.0
 Identities = 18/64 (28%), Positives = 33/64 (51%), Gaps = 1/64 (1%)

Query: 182  GGARGQATDIAIQAEEIMKLKKQLYNIYAKHTKQSLQVIESAMERDRYMSPMEAQEFGIL 241
            G ARGQ   + +   + + +  +    Y + T++ LQV+ +  E D Y +  +A  FG+L
Sbjct: 2170 GAARGQNFHLVVNCFKCVTILVKKVKSY-QITEKQLQVLLAYAEEDIYDTSRQATAFGLL 2228

Query: 242  DKVL 245
              +L
Sbjct: 2229 KAIL 2232


>gi|157388904 HEAT repeat containing 2 [Homo sapiens]
          Length = 855

 Score = 28.9 bits (63), Expect = 5.2
 Identities = 15/31 (48%), Positives = 19/31 (61%)

Query: 18  PALGPRLAAHFPAQRPPQRTLQNGLALQRCL 48
           PAL  RLA   PA+RPP+   +  LAL + L
Sbjct: 119 PALAARLAGPVPARRPPEACEELRLALVQLL 149


>gi|13435377 glucocorticoid modulatory element binding protein 1
           isoform 1 [Homo sapiens]
          Length = 573

 Score = 28.5 bits (62), Expect = 6.7
 Identities = 39/185 (21%), Positives = 73/185 (39%), Gaps = 26/185 (14%)

Query: 92  DDSVASLVIAQLLFLQSESNKKPIHMYINSPGG--VVTAGLAIYDTMQYILNPICTWCVG 149
           D  + S  +  ++ +   + K P    +  P    V++    +      +++PI    VG
Sbjct: 355 DHRLKSQTVQNVVLMPVSTPKPPKRPRLQRPASTTVLSPSPPVQQPQFTVISPITITPVG 414

Query: 150 QAASMGSLLLAAGTPGMRHSLPNSRIMIHQ-PSGGARGQATDIAIQAEEIMKLKKQLYNI 208
           Q+ SMG++ +A  + G      +S + +H  PSG        +   A  +   K    + 
Sbjct: 415 QSFSMGNIPVATLSQG------SSPVTVHTLPSG------PQLFRYATVVSSAKSSSPDT 462

Query: 209 YAKHTKQSLQVIESAMERD--------RYMSPME--AQEFGILDKVLVHPPQDGEDEPTL 258
              H   SL ++ S   +D          +SP+E  A E G L   +       ED  T+
Sbjct: 463 VTIHPSSSLALLSSTAMQDGSTLGNMTTMVSPVELVAMESG-LTSAIQAVESTSEDGQTI 521

Query: 259 VQKEP 263
           ++ +P
Sbjct: 522 IEIDP 526


>gi|13435375 glucocorticoid modulatory element binding protein 1
           isoform 2 [Homo sapiens]
          Length = 563

 Score = 28.5 bits (62), Expect = 6.7
 Identities = 39/185 (21%), Positives = 73/185 (39%), Gaps = 26/185 (14%)

Query: 92  DDSVASLVIAQLLFLQSESNKKPIHMYINSPGG--VVTAGLAIYDTMQYILNPICTWCVG 149
           D  + S  +  ++ +   + K P    +  P    V++    +      +++PI    VG
Sbjct: 345 DHRLKSQTVQNVVLMPVSTPKPPKRPRLQRPASTTVLSPSPPVQQPQFTVISPITITPVG 404

Query: 150 QAASMGSLLLAAGTPGMRHSLPNSRIMIHQ-PSGGARGQATDIAIQAEEIMKLKKQLYNI 208
           Q+ SMG++ +A  + G      +S + +H  PSG        +   A  +   K    + 
Sbjct: 405 QSFSMGNIPVATLSQG------SSPVTVHTLPSG------PQLFRYATVVSSAKSSSPDT 452

Query: 209 YAKHTKQSLQVIESAMERD--------RYMSPME--AQEFGILDKVLVHPPQDGEDEPTL 258
              H   SL ++ S   +D          +SP+E  A E G L   +       ED  T+
Sbjct: 453 VTIHPSSSLALLSSTAMQDGSTLGNMTTMVSPVELVAMESG-LTSAIQAVESTSEDGQTI 511

Query: 259 VQKEP 263
           ++ +P
Sbjct: 512 IEIDP 516


>gi|226958575 RAS protein activator like 2 isoform 2 [Homo sapiens]
          Length = 1280

 Score = 28.1 bits (61), Expect = 8.8
 Identities = 21/89 (23%), Positives = 39/89 (43%), Gaps = 5/89 (5%)

Query: 112 KKPIHMYINSPGGVVTAGLAIYDTMQYILNPICTWCVGQAASMGSLLLAAGTPGMRHSLP 171
           ++P+H  +N PGG+    L+  + + ++ NPI        AS+ S L    T   R    
Sbjct: 904 RRPLHPALNQPGGL--QPLSFQNPVYHLNNPIPAM---PKASIDSSLENLSTASSRSQSN 958

Query: 172 NSRIMIHQPSGGARGQATDIAIQAEEIMK 200
           +    +  PS  +    T  + Q+E+  +
Sbjct: 959 SEDFKLSGPSNSSMEDFTKRSTQSEDFSR 987


>gi|4758808 RAS protein activator like 2 isoform 1 [Homo sapiens]
          Length = 1139

 Score = 28.1 bits (61), Expect = 8.8
 Identities = 21/89 (23%), Positives = 39/89 (43%), Gaps = 5/89 (5%)

Query: 112 KKPIHMYINSPGGVVTAGLAIYDTMQYILNPICTWCVGQAASMGSLLLAAGTPGMRHSLP 171
           ++P+H  +N PGG+    L+  + + ++ NPI        AS+ S L    T   R    
Sbjct: 763 RRPLHPALNQPGGL--QPLSFQNPVYHLNNPIPAM---PKASIDSSLENLSTASSRSQSN 817

Query: 172 NSRIMIHQPSGGARGQATDIAIQAEEIMK 200
           +    +  PS  +    T  + Q+E+  +
Sbjct: 818 SEDFKLSGPSNSSMEDFTKRSTQSEDFSR 846


>gi|78190495 Kv channel interacting protein 3 isoform 2 [Homo
           sapiens]
          Length = 230

 Score = 28.1 bits (61), Expect = 8.8
 Identities = 12/49 (24%), Positives = 26/49 (53%)

Query: 193 IQAEEIMKLKKQLYNIYAKHTKQSLQVIESAMERDRYMSPMEAQEFGIL 241
           I  EE++ + K +Y++  +HT   L+    A   +R+   M+  + G++
Sbjct: 156 ITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFFEKMDRNQDGVV 204


>gi|7305199 Kv channel interacting protein 3 isoform 1 [Homo
           sapiens]
          Length = 256

 Score = 28.1 bits (61), Expect = 8.8
 Identities = 12/49 (24%), Positives = 26/49 (53%)

Query: 193 IQAEEIMKLKKQLYNIYAKHTKQSLQVIESAMERDRYMSPMEAQEFGIL 241
           I  EE++ + K +Y++  +HT   L+    A   +R+   M+  + G++
Sbjct: 182 ITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFFEKMDRNQDGVV 230


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,195,912
Number of Sequences: 37866
Number of extensions: 493214
Number of successful extensions: 1513
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1499
Number of HSP's gapped (non-prelim): 23
length of query: 277
length of database: 18,247,518
effective HSP length: 101
effective length of query: 176
effective length of database: 14,423,052
effective search space: 2538457152
effective search space used: 2538457152
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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