Search of human proteins with 51477714

Search of human proteins with 51477714

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|51477714 mannosidase, alpha, class 2A, member 1 [Homo
sapiens]
         (1144 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|51477714 mannosidase, alpha, class 2A, member 1 [Homo sapiens]    2320   0.0  
gi|51477716 mannosidase, alpha, class 2A, member 2 [Homo sapiens]    1241   0.0  
gi|50659093 mannosidase, alpha, class 2B, member 2 [Homo sapiens]     281   3e-75
gi|51873064 mannosidase, alpha, class 2B, member 1 precursor [Ho...   280   7e-75
gi|46852164 mannosidase, alpha, class 2C, member 1 [Homo sapiens]      47   1e-04
gi|4885583 Rho-associated, coiled-coil containing protein kinase...    35   0.53 
gi|217416390 carboxypeptidase A2 (pancreatic) precursor [Homo sa...    33   1.2  
gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens]                    32   2.6  
gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens]        31   7.7  
gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens]        31   7.7  
gi|51599156 chromodomain helicase DNA binding protein 4 [Homo sa...    31   7.7  
gi|148612829 RUN and TBC1 domain containing 1 isoform 2 [Homo sa...    31   7.7  
gi|148612795 RUN and TBC1 domain containing 1 isoform 1 [Homo sa...    31   7.7  

>gi|51477714 mannosidase, alpha, class 2A, member 1 [Homo sapiens]
          Length = 1144

 Score = 2320 bits (6011), Expect = 0.0
 Identities = 1144/1144 (100%), Positives = 1144/1144 (100%)

Query: 1    MKLSRQFTVFGSAIFCVVIFSLYLMLDRGHLDYPRNPRREGSFPQGQLSMLQEKIDHLER 60
            MKLSRQFTVFGSAIFCVVIFSLYLMLDRGHLDYPRNPRREGSFPQGQLSMLQEKIDHLER
Sbjct: 1    MKLSRQFTVFGSAIFCVVIFSLYLMLDRGHLDYPRNPRREGSFPQGQLSMLQEKIDHLER 60

Query: 61   LLAENNEIISNIRDSVINLSESVEDGPKSSQSNFSQGAGSHLLPSQLSLSVDTADCLFAS 120
            LLAENNEIISNIRDSVINLSESVEDGPKSSQSNFSQGAGSHLLPSQLSLSVDTADCLFAS
Sbjct: 61   LLAENNEIISNIRDSVINLSESVEDGPKSSQSNFSQGAGSHLLPSQLSLSVDTADCLFAS 120

Query: 121  QSGSHNSDVQMLDVYSLISFDNPDGGVWKQGFDITYESNEWDTEPLQVFVVPHSHNDPGW 180
            QSGSHNSDVQMLDVYSLISFDNPDGGVWKQGFDITYESNEWDTEPLQVFVVPHSHNDPGW
Sbjct: 121  QSGSHNSDVQMLDVYSLISFDNPDGGVWKQGFDITYESNEWDTEPLQVFVVPHSHNDPGW 180

Query: 181  LKTFNDYFRDKTQYIFNNMVLKLKEDSRRKFIWSEISYLSKWWDIIDIQKKDAVKSLIEN 240
            LKTFNDYFRDKTQYIFNNMVLKLKEDSRRKFIWSEISYLSKWWDIIDIQKKDAVKSLIEN
Sbjct: 181  LKTFNDYFRDKTQYIFNNMVLKLKEDSRRKFIWSEISYLSKWWDIIDIQKKDAVKSLIEN 240

Query: 241  GQLEIVTGGWVMPDEATPHYFALIDQLIEGHQWLENNIGVKPRSGWAIDPFGHSPTMAYL 300
            GQLEIVTGGWVMPDEATPHYFALIDQLIEGHQWLENNIGVKPRSGWAIDPFGHSPTMAYL
Sbjct: 241  GQLEIVTGGWVMPDEATPHYFALIDQLIEGHQWLENNIGVKPRSGWAIDPFGHSPTMAYL 300

Query: 301  LNRAGLSHMLIQRVHYAVKKHFALHKTLEFFWRQNWDLGSVTDILCHMMPFYSYDIPHTC 360
            LNRAGLSHMLIQRVHYAVKKHFALHKTLEFFWRQNWDLGSVTDILCHMMPFYSYDIPHTC
Sbjct: 301  LNRAGLSHMLIQRVHYAVKKHFALHKTLEFFWRQNWDLGSVTDILCHMMPFYSYDIPHTC 360

Query: 361  GPDPKICCQFDFKRLPGGRFGCPWGVPPETIHPGNVQSRARMLLDQYRKKSKLFRTKVLL 420
            GPDPKICCQFDFKRLPGGRFGCPWGVPPETIHPGNVQSRARMLLDQYRKKSKLFRTKVLL
Sbjct: 361  GPDPKICCQFDFKRLPGGRFGCPWGVPPETIHPGNVQSRARMLLDQYRKKSKLFRTKVLL 420

Query: 421  APLGDDFRYCEYTEWDLQFKNYQQLFDYMNSQSKFKVKIQFGTLSDFFDALDKADETQRD 480
            APLGDDFRYCEYTEWDLQFKNYQQLFDYMNSQSKFKVKIQFGTLSDFFDALDKADETQRD
Sbjct: 421  APLGDDFRYCEYTEWDLQFKNYQQLFDYMNSQSKFKVKIQFGTLSDFFDALDKADETQRD 480

Query: 481  KGQSMFPVLSGDFFTYADRDDHYWSGYFTSRPFYKRMDRIMESHLRAAEILYYFALRQAH 540
            KGQSMFPVLSGDFFTYADRDDHYWSGYFTSRPFYKRMDRIMESHLRAAEILYYFALRQAH
Sbjct: 481  KGQSMFPVLSGDFFTYADRDDHYWSGYFTSRPFYKRMDRIMESHLRAAEILYYFALRQAH 540

Query: 541  KYKINKFLSSSLYTALTEARRNLGLFQHHDAITGTAKDWVVVDYGTRLFHSLMVLEKIIG 600
            KYKINKFLSSSLYTALTEARRNLGLFQHHDAITGTAKDWVVVDYGTRLFHSLMVLEKIIG
Sbjct: 541  KYKINKFLSSSLYTALTEARRNLGLFQHHDAITGTAKDWVVVDYGTRLFHSLMVLEKIIG 600

Query: 601  NSAFLLILKDKLTYDSYSPDTFLEMDLKQKSQDSLPQKNIIRLSAEPRYLVVYNPLEQDR 660
            NSAFLLILKDKLTYDSYSPDTFLEMDLKQKSQDSLPQKNIIRLSAEPRYLVVYNPLEQDR
Sbjct: 601  NSAFLLILKDKLTYDSYSPDTFLEMDLKQKSQDSLPQKNIIRLSAEPRYLVVYNPLEQDR 660

Query: 661  ISLVSVYVSSPTVQVFSASGKPVEVQVSAVWDTANTISETAYEISFRAHIPPLGLKVYKI 720
            ISLVSVYVSSPTVQVFSASGKPVEVQVSAVWDTANTISETAYEISFRAHIPPLGLKVYKI
Sbjct: 661  ISLVSVYVSSPTVQVFSASGKPVEVQVSAVWDTANTISETAYEISFRAHIPPLGLKVYKI 720

Query: 721  LESASSNSHLADYVLYKNKVEDSGIFTIKNMINTEEGITLENSFVLLRFDQTGLMKQMMT 780
            LESASSNSHLADYVLYKNKVEDSGIFTIKNMINTEEGITLENSFVLLRFDQTGLMKQMMT
Sbjct: 721  LESASSNSHLADYVLYKNKVEDSGIFTIKNMINTEEGITLENSFVLLRFDQTGLMKQMMT 780

Query: 781  KEDGKHHEVNVQFSWYGTTIKRDKSGAYLFLPDGNAKPYVYTTPPFVRVTHGRIYSEVTC 840
            KEDGKHHEVNVQFSWYGTTIKRDKSGAYLFLPDGNAKPYVYTTPPFVRVTHGRIYSEVTC
Sbjct: 781  KEDGKHHEVNVQFSWYGTTIKRDKSGAYLFLPDGNAKPYVYTTPPFVRVTHGRIYSEVTC 840

Query: 841  FFDHVTHRVRLYHIQGIEGQSVEVSNIVDIRKVYNREIAMKISSDIKSQNRFYTDLNGYQ 900
            FFDHVTHRVRLYHIQGIEGQSVEVSNIVDIRKVYNREIAMKISSDIKSQNRFYTDLNGYQ
Sbjct: 841  FFDHVTHRVRLYHIQGIEGQSVEVSNIVDIRKVYNREIAMKISSDIKSQNRFYTDLNGYQ 900

Query: 901  IQPRMTLSKLPLQANVYPMTTMAYIQDAKHRLTLLSAQSLGVSSLNSGQIEVIMDRRLMQ 960
            IQPRMTLSKLPLQANVYPMTTMAYIQDAKHRLTLLSAQSLGVSSLNSGQIEVIMDRRLMQ
Sbjct: 901  IQPRMTLSKLPLQANVYPMTTMAYIQDAKHRLTLLSAQSLGVSSLNSGQIEVIMDRRLMQ 960

Query: 961  DDNRGLEQGIQDNKITANLFRILLEKRSAVNTEEEKKSVSYPSLLSHITSSLMNHPVIPM 1020
            DDNRGLEQGIQDNKITANLFRILLEKRSAVNTEEEKKSVSYPSLLSHITSSLMNHPVIPM
Sbjct: 961  DDNRGLEQGIQDNKITANLFRILLEKRSAVNTEEEKKSVSYPSLLSHITSSLMNHPVIPM 1020

Query: 1021 ANKFSSPTLELQGEFSPLQSSLPCDIHLVNLRTIQSKVGNGHSNEAALILHRKGFDCRFS 1080
            ANKFSSPTLELQGEFSPLQSSLPCDIHLVNLRTIQSKVGNGHSNEAALILHRKGFDCRFS
Sbjct: 1021 ANKFSSPTLELQGEFSPLQSSLPCDIHLVNLRTIQSKVGNGHSNEAALILHRKGFDCRFS 1080

Query: 1081 SKGTGLFCSTTQGKILVQKLLNKFIVESLTPSSLSLMHSPPGTQNISEINLSPMEISTFR 1140
            SKGTGLFCSTTQGKILVQKLLNKFIVESLTPSSLSLMHSPPGTQNISEINLSPMEISTFR
Sbjct: 1081 SKGTGLFCSTTQGKILVQKLLNKFIVESLTPSSLSLMHSPPGTQNISEINLSPMEISTFR 1140

Query: 1141 IQLR 1144
            IQLR
Sbjct: 1141 IQLR 1144


>gi|51477716 mannosidase, alpha, class 2A, member 2 [Homo sapiens]
          Length = 1150

 Score = 1241 bits (3211), Expect = 0.0
 Identities = 623/1155 (53%), Positives = 815/1155 (70%), Gaps = 18/1155 (1%)

Query: 1    MKLSRQFTVFGSAIFCVVIFSLYLMLDRGHLDYPRNPRREGSFPQGQLSMLQEKIDHLER 60
            MKL +Q TV G+AIFCV +FSLYLMLDR   D P   +  G+FP+ Q+S+LQ +I+ LE+
Sbjct: 1    MKLKKQVTVCGAAIFCVAVFSLYLMLDRVQHD-PTRHQNGGNFPRSQISVLQNRIEQLEQ 59

Query: 61   LLAENNEIISNIRDSVINLSESVEDGPKSSQSNFSQGAGSHLLPSQLS---LSVDTADCL 117
            LL EN+EIIS+I+DSV+ L+ + E GP +    ++   GS ++P +      S+   DC 
Sbjct: 60   LLEENHEIISHIKDSVLELTANAE-GPPAMLPYYTVN-GSWVVPPEPRPSFFSISPQDCQ 117

Query: 118  FASQSGSHNSDVQMLDVYSLISFDNPDGGVWKQGFDITYESNEWDTEPLQVFVVPHSHND 177
            FA        ++QML V   + FDN DGGVW+QGFDI+Y+ ++WD E LQVFVVPHSHND
Sbjct: 118  FALGGRGQKPELQMLTVSEELPFDNVDGGVWRQGFDISYDPHDWDAEDLQVFVVPHSHND 177

Query: 178  PGWLKTFNDYFRDKTQYIFNNMVLKLKEDSRRKFIWSEISYLSKWWDIIDIQKKDAVKSL 237
            PGW+KTF+ Y+ ++TQ+I N+MV KL+ED RR+F+W+E+S+ +KWWD I++QK+ AV+ L
Sbjct: 178  PGWIKTFDKYYTEQTQHILNSMVSKLQEDPRRRFLWAEVSFFAKWWDNINVQKRAAVRRL 237

Query: 238  IENGQLEIVTGGWVMPDEATPHYFALIDQLIEGHQWLENNIGVKPRSGWAIDPFGHSPTM 297
            + NGQLEI TGGWVMPDEA  HYFALIDQLIEGHQWLE N+G  PRSGWA+DPFG+S TM
Sbjct: 238  VGNGQLEIATGGWVMPDEANSHYFALIDQLIEGHQWLERNLGATPRSGWAVDPFGYSSTM 297

Query: 298  AYLLNRAGLSHMLIQRVHYAVKKHFALHKTLEFFWRQNWDLGSVTDILCHMMPFYSYDIP 357
             YLL RA L+ MLIQRVHYA+KKHFA   +LEF WRQ WD  S TDI CHMMPFYSYD+P
Sbjct: 298  PYLLRRANLTSMLIQRVHYAIKKHFAATHSLEFMWRQTWDSDSSTDIFCHMMPFYSYDVP 357

Query: 358  HTCGPDPKICCQFDFKRLPGGRFGCPWGVPPETIHPGNVQSRARMLLDQYRKKSKLFRTK 417
            HTCGPDPKICCQFDFKRLPGGR  CPW VPP  I   NV  RA +LLDQYRKKS+LFR+ 
Sbjct: 358  HTCGPDPKICCQFDFKRLPGGRINCPWKVPPRAITEANVAERAALLLDQYRKKSQLFRSN 417

Query: 418  VLLAPLGDDFRYCEYTEWDLQFKNYQQLFDYMNSQSKFKVKIQFGTLSDFFDALDKADET 477
            VLL PLGDDFRY +  EWD QF NYQ+LFD+ NS+    V+ QFGTLSD+FDAL K    
Sbjct: 418  VLLVPLGDDFRYDKPQEWDAQFFNYQRLFDFFNSRPNLHVQAQFGTLSDYFDALYKRTGV 477

Query: 478  QRDKGQSMFPVLSGDFFTYADRDDHYWSGYFTSRPFYKRMDRIMESHLRAAEILYYFALR 537
            +       FPVLSGDFF+YADR+DHYW+GY+TSRPFYK +DR++E+HLR AE+LY  A  
Sbjct: 478  EPGARPPGFPVLSGDFFSYADREDHYWTGYYTSRPFYKSLDRVLEAHLRGAEVLYSLAAA 537

Query: 538  QAHKYKINKFLSSSLYTALTEARRNLGLFQHHDAITGTAKDWVVVDYGTRLFHSLMVLEK 597
             A +  +      S +T LTEARR LGLFQHHDAITGTAK+ VVVDYG RL  SL+ L++
Sbjct: 538  HARRSGLAGRYPLSDFTLLTEARRTLGLFQHHDAITGTAKEAVVVDYGVRLLRSLVNLKQ 597

Query: 598  IIGNSAFLLILKDKLTYDSYSPDTFLEMDLKQKSQDSLPQKNIIRLSAEPRYLVVYNPLE 657
            +I ++A  L+L DK TY       FL++D  + S D+LP++ +I+L + PR++V++NPLE
Sbjct: 598  VIIHAAHYLVLGDKETYHFDPEAPFLQVDDTRLSHDALPERTVIQLDSSPRFVVLFNPLE 657

Query: 658  QDRISLVSVYVSSPTVQVFSASGKPVEVQVSAVWDTANTISETAYEISFRAHIPPLGLKV 717
            Q+R S+VS+ V+SP V+V S  G+P+ VQ+SA W +A       Y++S    +P LGL V
Sbjct: 658  QERFSMVSLLVNSPRVRVLSEEGQPLAVQISAHWSSATEAVPDVYQVSVPVRLPALGLGV 717

Query: 718  YKILESASSNSHLADYV-LYKN----KVEDSGIFTIKNMINTEEGITLENSFVLLRFD-Q 771
             ++      +  L   V +Y +     V     F ++ + +      L N ++ + F   
Sbjct: 718  LQLQLGLDGHRTLPSSVRIYLHGRQLSVSRHEAFPLRVIDSGTSDFALSNRYMQVWFSGL 777

Query: 772  TGLMKQMMTKEDGKHHEVNVQFSWYGTTIKRDKSGAYLFLPDGNAKPYVYTTPPFVRVTH 831
            TGL+K +   ++    +V++Q   YGT   +DKSGAYLFLPDG AKPYV   PP +RVT 
Sbjct: 778  TGLLKSIRRVDEEHEQQVDMQVLVYGTRTSKDKSGAYLFLPDGEAKPYVPKEPPVLRVTE 837

Query: 832  GRIYSEVTCFFDHVTHRVRLYHIQGIEGQSVEVSNIVDIRKVYNREIAMKISSDIKSQNR 891
            G  +SEV  +++H+   VRLY++ G+EG S+++S++VDIR   N+E+A+ I +DI SQ  
Sbjct: 838  GPFFSEVVAYYEHIHQAVRLYNLPGVEGLSLDISSLVDIRDYVNKELALHIHTDIDSQGI 897

Query: 892  FYTDLNGYQIQPRMTLSKLPLQANVYPMTTMAYIQDAKHRLTLLSAQSLGVSSLNSGQIE 951
            F+TDLNG+Q+QPR  L KLPLQAN YPM  MAYIQDA+ RLTL +AQ+LGVSSL  GQ+E
Sbjct: 898  FFTDLNGFQVQPRRYLKKLPLQANFYPMPVMAYIQDAQKRLTLHTAQALGVSSLKDGQLE 957

Query: 952  VIMDRRLMQDDNRGLEQGIQDNKITANLFRILLEKRSAVNTEEEKKSVSYPSLLSHITSS 1011
            VI+DRRLMQDDNRGL QG++DNK T N FR+LLE+R+  +  ++  S SYPSLLSH+TS 
Sbjct: 958  VILDRRLMQDDNRGLGQGLKDNKRTCNRFRLLLERRTVGSEVQDSHSTSYPSLLSHLTSM 1017

Query: 1012 LMNHP--VIPMAN-KFSSPTLELQGEFSPLQSSLPCDIHLVNLRTIQSKVGNGHSNEAAL 1068
             +N P   +P+A  +   P L     F PL SSLPCD HL+NLRT+Q++     S E AL
Sbjct: 1018 YLNAPALALPVARMQLPGPGLR---SFHPLASSLPCDFHLLNLRTLQAEEDTLPSAETAL 1074

Query: 1069 ILHRKGFDCRFSSKGTGLFCSTTQGKILVQKLLNKFIVESLTPSSLSLMHSPPGTQNISE 1128
            ILHRKGFDC   +K  G  C+T+QGK+ +  L +   V  L P+SL+L++      N ++
Sbjct: 1075 ILHRKGFDCGLEAKNLGFNCTTSQGKVALGSLFHGLDVVFLQPTSLTLLYPLASPSNSTD 1134

Query: 1129 INLSPMEISTFRIQL 1143
            + L PMEI+TFR++L
Sbjct: 1135 VYLEPMEIATFRLRL 1149


>gi|50659093 mannosidase, alpha, class 2B, member 2 [Homo sapiens]
          Length = 1009

 Score =  281 bits (719), Expect = 3e-75
 Identities = 255/953 (26%), Positives = 416/953 (43%), Gaps = 120/953 (12%)

Query: 165  PLQVFVVPHSHNDPGWLKTFNDYFRDKTQYIFNNMVLKLKEDSRRKFIWSEISYLSKWWD 224
            P++ FVVPHSH D GW+ T  +  R     ++ ++V +L    +R+FI  E  +   WWD
Sbjct: 26   PIRAFVVPHSHMDVGWVYTVQESMRAYAANVYTSVVEELARGQQRRFIAVEQEFFRLWWD 85

Query: 225  -IIDIQKKDAVKSLIENGQLEIVTGGWVMPDEATPHYFALIDQLIEGHQWLENNIGVKPR 283
             +   Q+K  V+ L+E G+LE V GG VM DEA  H    I QL EGH +L    G++P+
Sbjct: 86   GVASDQQKYQVRQLLEEGRLEFVIGGQVMHDEAVTHLDDQILQLTEGHGFLYETFGIRPQ 145

Query: 284  SGWAIDPFGHSPTMAYLLNRAGLSHMLIQRVHYAVKKHFALHKTLEFFWRQNWDLGSVTD 343
              W +DPFG S T   L   AG +  L  R+ Y +K      + L+F WR +  L    +
Sbjct: 146  FSWHVDPFGASATTPTLFALAGFNAHLGSRIDYDLKAAMQEARGLQFVWRGSPSLSERQE 205

Query: 344  ILCHMMPFYSYDIPHTCGPDPKICCQFDFKRLP-GGRFGCPW------------GVPP-- 388
            I  H+M  YSY  P                 +P   R G  W            GV P  
Sbjct: 206  IFTHIMDQYSYCTP---------------SHIPFSNRSGFYWNGVAVFPKPPQDGVYPNM 250

Query: 389  -ETIHPGNVQSRARMLLDQYRKKSKLFRTKVLLAPLGDDFRYCEYTEWDLQFKNYQQLFD 447
             E + P N+   A  L+   ++++  FRT  +L P G D ++   +   +QF N   L D
Sbjct: 251  SEPVTPANINLYAEALVANVKQRAAWFRTPHVLWPWGCDKQFFNAS---VQFANMDPLLD 307

Query: 448  YMNSQ-SKFKVKIQFGTLSDFFDALDKADETQRDKGQSMFPVLSGDFFTYADRDDHYWSG 506
            ++NS  ++  V +Q+ TL D+F AL   + T R +          DF  Y+      W+G
Sbjct: 308  HINSHAAELGVSVQYATLGDYFRALHALNVTWRVRDHH-------DFLPYSTEPFQAWTG 360

Query: 507  YFTSRPFYKRMDRIMESHLRAAEILYYFALRQAHKYKINKFLSSSLYTALTEARRNLGLF 566
            ++TSR   K + R   + L A E ++   L  A +  ++    +     L + R  +   
Sbjct: 361  FYTSRSSLKGLARRASALLYAGESMFTRYLWPAPRGHLD---PTWALQQLQQLRWAVSEV 417

Query: 567  QHHDAITGTAKDWVVVDYGTRLFHSLMVLEKIIGNSAFLLILKDKLTYDSYSPDTFLEMD 626
            QHHDAITGT    V   Y T L   ++ + K++ +     I+ D+L              
Sbjct: 418  QHHDAITGTESPKVRDMYATHLASGMLGMRKLMAS-----IVLDEL-------------- 458

Query: 627  LKQKSQDSLPQKNIIRLSAEPRYLVVYNPLEQDRISLVSVYVSSPTVQVFSASGKPVEVQ 686
                 Q   P            +  VYNPL     ++V++ V  P V+V   +G PV  Q
Sbjct: 459  -----QPQAPMAASSDAGPAGHFASVYNPLAWTVTTIVTLTVGFPGVRVTDEAGHPVPSQ 513

Query: 687  VSAVWDTANTISETAYEISFRAHIPPLGLKVYKILESASSNSHLADYVLYKNKVEDSGIF 746
            +       +T + +AY++     IP L  + Y I  +A +     +           G  
Sbjct: 514  IQ-----NSTETPSAYDLLILTTIPGLSYRHYNIRPTAGAQEGTQEPAATVASTLQFGRR 568

Query: 747  TIKNMINTEEGI--TLENSFVLLRFDQTGLMKQMMTKEDGKHHEVNVQFSWY---GTTIK 801
              +   +    +     + +++L    T LM  +  ++  +   V  +F  Y   G   +
Sbjct: 569  LRRRTSHAGRYLVPVANDCYIVLLDQDTNLMHSIWERQSNRTVRVTQEFLEYHVNGDVKQ 628

Query: 802  RDKSGAYLFLPDGNAKPYVYTTPPFVRVTHGRIYSEVTCFF------DHVTH--RVRLYH 853
               S  YLF P   A P        + +  G++ +E+  +F       + T+  R RL H
Sbjct: 629  GPISDNYLFTPGKAAVPAWEAVE--MEIVAGQLVTEIRQYFYRNMTAQNYTYAIRSRLTH 686

Query: 854  I-QGIEGQSVEVSNIVDIRKVY-------NREIAMKISSDIKSQNRFYTDLNGYQIQPRM 905
            + QG +G+ +       I + Y       NRE  ++ S+++ SQ   Y+D NGYQ+Q R 
Sbjct: 687  VPQGHDGELL----CHRIEQEYQAGPLELNREAVLRTSTNLNSQQVIYSDNNGYQMQRRP 742

Query: 906  TLSKL--PLQANVYPMTTMAYIQDAKHRLTLLSAQSLGVSSLNSGQIEVIMDRRLMQ--D 961
             +S +   +  N YPM   A+++D K RL LLS ++ G+SS  +GQ+EV++ RRL    D
Sbjct: 743  YVSYVNNSIARNYYPMVQSAFMEDGKSRLVLLSERAHGISSQGNGQVEVMLHRRLWNNFD 802

Query: 962  DNRGLEQGIQDNKITANLFRILLEKRSAVNTEEEKKSVSYPSLLSHITSSLMNHPVIPMA 1021
             + G    + D  +   +  +LL   S      ++ ++           +L + PV+ + 
Sbjct: 803  WDLGYNLTLNDTSVVHPVLWLLLGSWSLTTALRQRSAL-----------ALQHRPVV-LF 850

Query: 1022 NKFSSPTLELQGEFSPLQSSLPCDIHLVNLRTIQSKVGNGHSNEAALILHRKG 1074
               +    +L G       +LP ++HL  L     +  + H+  +  +  RKG
Sbjct: 851  GDLAGTAPKLPGPQQQEAVTLPPNLHLQILSIPGWRYSSNHTEHSQNL--RKG 901


>gi|51873064 mannosidase, alpha, class 2B, member 1 precursor [Homo
            sapiens]
          Length = 1011

 Score =  280 bits (715), Expect = 7e-75
 Identities = 272/1027 (26%), Positives = 448/1027 (43%), Gaps = 142/1027 (13%)

Query: 166  LQVFVVPHSHNDPGWLKTFNDYF--------RDKTQYIFNNMVLKLKEDSRRKFIWSEIS 217
            L V ++PH+H+D GWLKT + YF            QYI ++++  L  D  R+FI+ EI+
Sbjct: 63   LNVHLLPHTHDDVGWLKTVDQYFYGIKNDIQHAGVQYILDSVISALLADPTRRFIYVEIA 122

Query: 218  YLSKWWDIIDIQKKDAVKSLIENGQLEIVTGGWVMPDEATPHYFALIDQLIEGHQWLENN 277
            + S+WW       ++ V+ L+  G+LE   GGWVM DEA  HY A++DQ+  G ++LE+ 
Sbjct: 123  FFSRWWHQQTNATQEVVRDLVRQGRLEFANGGWVMNDEAATHYGAIVDQMTLGLRFLEDT 182

Query: 278  IG--VKPRSGWAIDPFGHSPTMAYLLNRAGLSHMLIQRVHYAVKKHFALHKTLEFFWRQN 335
             G   +PR  W IDPFGHS   A L  + G       R+ Y  K        +E  WR +
Sbjct: 183  FGNDGRPRVAWHIDPFGHSREQASLFAQMGFDGFFFGRLDYQDKWVRMQKLEMEQVWRAS 242

Query: 336  WDLGSVTDILCHMMPFYSYDIPHTCGPDPKICCQFDFKRLPGGRFGCPWGV----PPETI 391
              L   T  L      ++  +P+   P   +C                W V     P   
Sbjct: 243  TSLKPPTADL------FTGVLPNGYNPPRNLC----------------WDVLCVDQPLVE 280

Query: 392  HPGNVQSRARMLLDQY----RKKSKLFRTKVLLAPLGDDFRYCEYTEWDLQFKNYQQLFD 447
             P + +  A+ L+D +      + + +RT   +  +G DF+Y     W   FKN  +L  
Sbjct: 281  DPRSPEYNAKELVDYFLNVATAQGRYYRTNHTVMTMGSDFQYENANMW---FKNLDKLIR 337

Query: 448  YMNSQSK--FKVKIQFGTLSDFFDALDKADETQRDKGQSMFPVLSGDFFTYADRDDHYWS 505
             +N+Q      V + + T + +   L+KA+ T        + V   DFF YAD    +W+
Sbjct: 338  LVNAQQAKGSSVHVLYSTPACYLWELNKANLT--------WSVKHDDFFPYADGPHQFWT 389

Query: 506  GYFTSRPFYKRMDRIMESHLRAAEILYYFALRQAHKYKINKFLSSSLYTALTEARRNLGL 565
            GYF+SRP  KR +R+  + L+    L       A+        S+ L  A       + +
Sbjct: 390  GYFSSRPALKRYERLSYNFLQVCNQLEALVGLAANVGPYGSGDSAPLNEA-------MAV 442

Query: 566  FQHHDAITGTAKDWVVVDYGTRLFHSLMVLEKIIGNS-AFLLILKDKLTYDSYSPDTFLE 624
             QHHDA++GT++  V  DY  +L       E ++ N+ A L   KD  T+        L 
Sbjct: 443  LQHHDAVSGTSRQHVANDYARQLAAGWGPCEVLLSNALARLRGFKDHFTFCQQ-----LN 497

Query: 625  MDLKQKSQDSLPQKNIIRLSAEPRYLVVYNPLEQDRISLVSVYVSSPTVQVFSASGKPVE 684
            + +   SQ           +A    ++VYNPL +    +V + VS     V   +G+ V 
Sbjct: 498  ISICPLSQ-----------TAARFQVIVYNPLGRKVNWMVRLPVSEGVFVVKDPNGRTVP 546

Query: 685  VQVSAVWDTANTISETAYEISFRAHIPPLGLKVYKILESASSNSHLADYVLYKNKVEDSG 744
              V  ++ ++++ +    E+ F A +P LG   Y +          A    +K +     
Sbjct: 547  SDV-VIFPSSDSQAHPP-ELLFSASLPALGFSTYSV----------AQVPRWKPQARAPQ 594

Query: 745  IFTIKNMINTEEGITLENSFVLLRFD-QTGLMKQMMTKEDGKHHEVNVQFSWYGTTIKRD 803
                ++       +T+EN  +   FD  TGL+ ++M         V   F WY  +I  +
Sbjct: 595  PIPRRSW---SPALTIENEHIRATFDPDTGLLMEIMNMNQQLLLPVRQTFFWYNASIGDN 651

Query: 804  K----SGAYLFLPDGNAKPYVYTTPPFVRVTHGRIYSEV-TCFFDHVTHRVRLYHIQGIE 858
            +    SGAY+F P+   KP   +    + +    +  EV   F    +  VRLY   G  
Sbjct: 652  ESDQASGAYIFRPN-QQKPLPVSRWAQIHLVKTPLVQEVHQNFSAWCSQVVRLY--PGQR 708

Query: 859  GQSVEVS-NIVDIRKVYNREIAMKISSDIKSQNRFYTDLNGYQI-------QPRMTLSKL 910
               +E S   + +   + +E+  +  + ++++ RFYTD NG +I       +P   L++ 
Sbjct: 709  HLELEWSVGPIPVGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYRPTWKLNQT 768

Query: 911  -PLQANVYPMTTMAYIQDAKHRLTLLSAQSLGVSSLNSGQIEVIMDRRLMQDDNRGLEQG 969
             P+  N YP+ T  YI D   +LT+L+ +S G SSL  G +E+++ RRL++DD RG+ + 
Sbjct: 769  EPVAGNYYPVNTRIYITDGNMQLTVLTDRSQGGSSLRDGSLELMVHRRLLKDDGRGVSEP 828

Query: 970  IQDNKITANLFRILLEKRSAVNTEEEKKSVSYPSLLSH---ITSSLMNHPVIPMANKFSS 1026
            + +N   A      +  R  V  +  + + +   LL+    +   ++  P    A    +
Sbjct: 829  LMENGSGA-----WVRGRHLVLLDTAQAAAAGHRLLAEQEVLAPQVVLAPGGGAAYNLGA 883

Query: 1027 PTLELQGEFSPLQSSLPCDIHLVNLRT-----------IQSKVG--NGHSNEAALILHRK 1073
            P    + +FS L+  LP  +HL+ L +            Q  VG  +G +  A + L+ +
Sbjct: 884  PP---RTQFSGLRRDLPPSVHLLTLASWGPEMVLLRLEHQFAVGEDSGRNLSAPVTLNLR 940

Query: 1074 GFDCRFSSKGTGLFCSTTQGKILVQKLLNKFIVE-SLTPSSLSLMHSPPGTQNISEINLS 1132
                 F+        +  Q   LV   L +       T ++    H  P   + + I L 
Sbjct: 941  DLFSTFT-------ITRLQETTLVANQLREAASRLKWTTNTGPTPHQTPYQLDPANITLE 993

Query: 1133 PMEISTF 1139
            PMEI TF
Sbjct: 994  PMEIRTF 1000


>gi|46852164 mannosidase, alpha, class 2C, member 1 [Homo sapiens]
          Length = 1040

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 45/182 (24%), Positives = 72/182 (39%), Gaps = 9/182 (4%)

Query: 173 HSHNDPGWLKTFNDYFRDKTQYIFNNMVLKLKEDSRRKFIWSEISYLSKWWDIIDIQKKD 232
           H H D  WL  F +  R   +     + L ++ +    F  S+   L +W          
Sbjct: 258 HCHIDTAWLWPFKETVRKCARSWVTALQL-MERNPEFIFACSQAQQL-EWVKSRYPGLYS 315

Query: 233 AVKSLIENGQLEIVTGGWVMPDEATPHYFALIDQLIEGHQWLENNIGVKPRSGWAIDPFG 292
            ++     GQ   V G WV  D   P   A++ Q ++G  +     G      W  D FG
Sbjct: 316 RIQEFACRGQFVPVGGTWVEMDGNLPSGEAMVRQFLQGQNFFLQEFGKMCSEFWLPDTFG 375

Query: 293 HSPTMAYLLNRAGLSHMLIQRVHYAVKKHFALHKTLEFFWRQNWDLGSVTDILCHMMPFY 352
           +S  +  +++  G+   L Q++ + +   F  H    FFW +  D GS   +L H  P  
Sbjct: 376 YSAQLPQIMHGCGIRRFLTQKLSWNLVNSFPHH---TFFW-EGLD-GS--RVLVHFPPGD 428

Query: 353 SY 354
           SY
Sbjct: 429 SY 430


>gi|4885583 Rho-associated, coiled-coil containing protein kinase 1
           [Homo sapiens]
          Length = 1354

 Score = 34.7 bits (78), Expect = 0.53
 Identities = 30/96 (31%), Positives = 46/96 (47%), Gaps = 8/96 (8%)

Query: 31  LDYPRNPRREGSFPQGQLS----MLQEKIDHLERLLAENNEIISNIRDSVINLSESVEDG 86
           LD   N RR       Q+     +LQ +I+  +R   + NE   N+ + V  L + +ED 
Sbjct: 467 LDEEGNQRRNLESTVSQIEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDL 526

Query: 87  PKSSQSNFSQGAGSHLLPSQLSLSVDTADCLFASQS 122
            K SQ+  SQ A   L  SQL   ++ A+ L  ++S
Sbjct: 527 KKVSQN--SQLANEKL--SQLQKQLEEANDLLRTES 558


>gi|217416390 carboxypeptidase A2 (pancreatic) precursor [Homo
           sapiens]
          Length = 419

 Score = 33.5 bits (75), Expect = 1.2
 Identities = 36/149 (24%), Positives = 62/149 (41%), Gaps = 19/149 (12%)

Query: 15  FCVVIFSLYLMLDRGHLD--YPRNPRREGSFPQGQLSMLQEKIDHLERLLAENNEIISNI 72
           + ++I  + ++LD+ + +  + R   R G+F  G    L+E    ++ L+AE+  ++S  
Sbjct: 88  YSIMIEDVQVLLDKENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDNLVAEHPGLVSK- 146

Query: 73  RDSVINLSESVEDGPKSSQSNFSQG---------AGSHLLPSQLSLSVDTADCLFASQSG 123
               +N+  S E+ P  +   FS G         AG H        +         S  G
Sbjct: 147 ----VNIGSSFENRP-MNVLKFSTGGDKPAIWLDAGIHAREWVTQATALWTANKIVSDYG 201

Query: 124 SHNSDVQMLDVYS--LISFDNPDGGVWKQ 150
              S   +LD     L+   NPDG V+ Q
Sbjct: 202 KDPSITSILDALDIFLLPVTNPDGYVFSQ 230


>gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens]
          Length = 898

 Score = 32.3 bits (72), Expect = 2.6
 Identities = 22/64 (34%), Positives = 30/64 (46%), Gaps = 6/64 (9%)

Query: 35  RNPRREGS------FPQGQLSMLQEKIDHLERLLAENNEIISNIRDSVINLSESVEDGPK 88
           R+P   GS      FPQ   +ML E+I  L++  A  NE I  + D +  L E +    K
Sbjct: 739 RSPENTGSSVAVDNFPQVDKAMLIERIVRLQKAHARKNEKIEFMEDHIKQLVEEIRKKTK 798

Query: 89  SSQS 92
             QS
Sbjct: 799 IIQS 802


>gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens]
          Length = 1040

 Score = 30.8 bits (68), Expect = 7.7
 Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 6/83 (7%)

Query: 678 ASGKPVEVQVSAVWDTANTISETAYEISFRAHIPPLGLKVYKIL---ESASSNSHLADYV 734
           ++ K ++VQVS V D A   S+  Y++    +  P G  +Y +        +N+ LA Y 
Sbjct: 444 STSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVP-GAYIYAVSATDRDEGANAQLA-YS 501

Query: 735 LYKNKVEDSGIFTIKNMINTEEG 757
           + + +++   +FT  + IN+E G
Sbjct: 502 ILECQIQGMSVFTYVS-INSENG 523


>gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens]
          Length = 896

 Score = 30.8 bits (68), Expect = 7.7
 Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 6/83 (7%)

Query: 678 ASGKPVEVQVSAVWDTANTISETAYEISFRAHIPPLGLKVYKIL---ESASSNSHLADYV 734
           ++ K ++VQVS V D A   S+  Y++    +  P G  +Y +        +N+ LA Y 
Sbjct: 444 STSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVP-GAYIYAVSATDRDEGANAQLA-YS 501

Query: 735 LYKNKVEDSGIFTIKNMINTEEG 757
           + + +++   +FT  + IN+E G
Sbjct: 502 ILECQIQGMSVFTYVS-INSENG 523


>gi|51599156 chromodomain helicase DNA binding protein 4 [Homo
           sapiens]
          Length = 1912

 Score = 30.8 bits (68), Expect = 7.7
 Identities = 12/29 (41%), Positives = 21/29 (72%)

Query: 888 SQNRFYTDLNGYQIQPRMTLSKLPLQANV 916
           +Q++F+  LNGY +Q ++ L+  PLQ N+
Sbjct: 881 NQSKFFRVLNGYSLQHKLLLTGTPLQNNL 909


>gi|148612829 RUN and TBC1 domain containing 1 isoform 2 [Homo
           sapiens]
          Length = 1006

 Score = 30.8 bits (68), Expect = 7.7
 Identities = 27/97 (27%), Positives = 49/97 (50%), Gaps = 7/97 (7%)

Query: 57  HLERLLAENNEIISNIRDSVINLSESVEDGPKSSQSNFSQGA-----GSHLLPSQLSLSV 111
           H++RL+  ++ I +++  SV +L       P+ S+    Q A     G+ ++  Q S+  
Sbjct: 641 HVQRLIHRDSTISNDVFISVDDLEPPEPQDPEDSRPKPEQEAGPGTPGTAVVEQQHSVEF 700

Query: 112 DTADC-LFASQSGSHNSDVQ-MLDVYSLISFDNPDGG 146
           D+ D  L +S++ S  S +Q  LD    + F+  DGG
Sbjct: 701 DSPDSGLPSSRNYSVASGIQSSLDEGQSVGFEEEDGG 737


>gi|148612795 RUN and TBC1 domain containing 1 isoform 1 [Homo
           sapiens]
          Length = 1051

 Score = 30.8 bits (68), Expect = 7.7
 Identities = 27/97 (27%), Positives = 49/97 (50%), Gaps = 7/97 (7%)

Query: 57  HLERLLAENNEIISNIRDSVINLSESVEDGPKSSQSNFSQGA-----GSHLLPSQLSLSV 111
           H++RL+  ++ I +++  SV +L       P+ S+    Q A     G+ ++  Q S+  
Sbjct: 686 HVQRLIHRDSTISNDVFISVDDLEPPEPQDPEDSRPKPEQEAGPGTPGTAVVEQQHSVEF 745

Query: 112 DTADC-LFASQSGSHNSDVQ-MLDVYSLISFDNPDGG 146
           D+ D  L +S++ S  S +Q  LD    + F+  DGG
Sbjct: 746 DSPDSGLPSSRNYSVASGIQSSLDEGQSVGFEEEDGG 782


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,847,416
Number of Sequences: 37866
Number of extensions: 1863529
Number of successful extensions: 4313
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 4280
Number of HSP's gapped (non-prelim): 17
length of query: 1144
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1031
effective length of database: 13,968,660
effective search space: 14401688460
effective search space used: 14401688460
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.