Guide to the Human Genome
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Search of human proteins with 50593112

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|50593112 nudix-type motif 13 [Homo sapiens]
         (352 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|50593112 nudix-type motif 13 [Homo sapiens]                        717   0.0  
gi|13899267 nudix-type motif 12 [Homo sapiens]                        163   2e-40
gi|40288286 nudix-type motif 1 isoform p22 [Homo sapiens]              36   0.045
gi|40288284 nudix-type motif 1 isoform p18 [Homo sapiens]              36   0.045
gi|40288282 nudix-type motif 1 isoform p22 [Homo sapiens]              36   0.045
gi|40288280 nudix-type motif 1 isoform p18 [Homo sapiens]              36   0.045
gi|40288278 nudix-type motif 1 isoform p22 [Homo sapiens]              36   0.045
gi|40288276 nudix-type motif 1 isoform p18 [Homo sapiens]              36   0.045
gi|40288274 nudix-type motif 1 isoform p18 [Homo sapiens]              36   0.045
gi|20149583 nudix-type motif 6 isoform a [Homo sapiens]                32   1.1  
gi|8922792 nudix-type motif 15 [Homo sapiens]                          30   2.5  
gi|118026927 nudix (nucleoside diphosphate linked moiety X)-type...    30   3.3  

>gi|50593112 nudix-type motif 13 [Homo sapiens]
          Length = 352

 Score =  717 bits (1850), Expect = 0.0
 Identities = 352/352 (100%), Positives = 352/352 (100%)

Query: 1   MSLYCGIACRRKFFWCYRLLSTYVTKTRYLFELKEDDDACKKAQQTGAFYLFHSLAPLLQ 60
           MSLYCGIACRRKFFWCYRLLSTYVTKTRYLFELKEDDDACKKAQQTGAFYLFHSLAPLLQ
Sbjct: 1   MSLYCGIACRRKFFWCYRLLSTYVTKTRYLFELKEDDDACKKAQQTGAFYLFHSLAPLLQ 60

Query: 61  TSAHQYLAPRHSLLELERLLGKFGQDAQRIEDSVLIGCSEQQEAWFALDLGLDSSFSISA 120
           TSAHQYLAPRHSLLELERLLGKFGQDAQRIEDSVLIGCSEQQEAWFALDLGLDSSFSISA
Sbjct: 61  TSAHQYLAPRHSLLELERLLGKFGQDAQRIEDSVLIGCSEQQEAWFALDLGLDSSFSISA 120

Query: 121 SLHKPEMETELKGSFIELRKALFQLNARDASLLSTAQALLRWHDAHQFCSRSGQPTKKNV 180
           SLHKPEMETELKGSFIELRKALFQLNARDASLLSTAQALLRWHDAHQFCSRSGQPTKKNV
Sbjct: 121 SLHKPEMETELKGSFIELRKALFQLNARDASLLSTAQALLRWHDAHQFCSRSGQPTKKNV 180

Query: 181 AGSKRVCPSNNIIYYPQMAPVAITLVSDGTRCLLARQSSFPKGMYSALAGFCDIGESVEE 240
           AGSKRVCPSNNIIYYPQMAPVAITLVSDGTRCLLARQSSFPKGMYSALAGFCDIGESVEE
Sbjct: 181 AGSKRVCPSNNIIYYPQMAPVAITLVSDGTRCLLARQSSFPKGMYSALAGFCDIGESVEE 240

Query: 241 TIRREVAEEVGLEVESLQYYASQHWPFPSGSLMIACHATVKPGQTEIQVNLRELETAAWF 300
           TIRREVAEEVGLEVESLQYYASQHWPFPSGSLMIACHATVKPGQTEIQVNLRELETAAWF
Sbjct: 241 TIRREVAEEVGLEVESLQYYASQHWPFPSGSLMIACHATVKPGQTEIQVNLRELETAAWF 300

Query: 301 SHDEVATALKRKGPYTQQQNGTFPFWLPPKLAISHQLIKEWVEKQTCSSLPA 352
           SHDEVATALKRKGPYTQQQNGTFPFWLPPKLAISHQLIKEWVEKQTCSSLPA
Sbjct: 301 SHDEVATALKRKGPYTQQQNGTFPFWLPPKLAISHQLIKEWVEKQTCSSLPA 352


>gi|13899267 nudix-type motif 12 [Homo sapiens]
          Length = 462

 Score =  163 bits (413), Expect = 2e-40
 Identities = 116/307 (37%), Positives = 164/307 (53%), Gaps = 45/307 (14%)

Query: 55  LAPLLQTSAHQYLAPRHSL--------LELERLLGKFGQDAQRIEDSVLIGCSEQQEAWF 106
           L  L  T    YLA    +        LE++  L  +  +  R E+  L+       AWF
Sbjct: 176 LCQLNYTDIKDYLAQPEKITLIFLGVELEIKDKLLNYAGEVPREEEDGLV-------AWF 228

Query: 107 ALDLGLDSSFSISASLHKPEMETELKGSFIEL-RKALFQLNARDASLLSTAQALLRWHDA 165
           AL  G+D    I+A   K   E      F+     AL QL  ++A +++ A+++L WH  
Sbjct: 229 AL--GIDP---IAAEEFKQRHENCY---FLHPPMPALLQLKEKEAGVVAQARSVLAWHSR 280

Query: 166 HQFCSRSGQPTKKNVAGSKRVC-----PSNNIIY---YPQMAPVAITLV--SDGTRCLLA 215
           ++FC   G  TK    G KR+C     PS N ++   YP++ PV I  V   DGT+CLL 
Sbjct: 281 YKFCPTCGNATKIEEGGYKRLCLKEDCPSLNGVHNTSYPRVDPVVIMQVIHPDGTKCLLG 340

Query: 216 RQSSFPKGMYSALAGFCDIGESVEETIRREVAEEVGLEVESLQYYASQHWPFPSGSLMIA 275
           RQ  FP GM++ LAGF + GE++E+ +RREV EE G++V  +QY A Q WP PS SLMI 
Sbjct: 341 RQKRFPPGMFTCLAGFIEPGETIEDAVRREVEEESGVKVGHVQYVACQPWPMPS-SLMIG 399

Query: 276 CHATVKPGQTEIQVNLRELETAAWFSHDEVATALKRKGPYTQQQNGTFPFWLPPKLAISH 335
           C A      TEI+V+  E+E A WF+ ++V   L +     +QQ     F++PP  AI+H
Sbjct: 400 CLALAV--STEIKVDKNEIEDARWFTREQVLDVLTK----GKQQ----AFFVPPSRAIAH 449

Query: 336 QLIKEWV 342
           QLIK W+
Sbjct: 450 QLIKHWI 456


>gi|40288286 nudix-type motif 1 isoform p22 [Homo sapiens]
          Length = 179

 Score = 36.2 bits (82), Expect = 0.045
 Identities = 27/104 (25%), Positives = 44/104 (42%), Gaps = 2/104 (1%)

Query: 203 ITLVSDGTRCLLA-RQSSFPKGMYSALAGFCDIGESVEETIRREVAEEVGLEVESLQYYA 261
           + LV    R LL  ++  F  G ++   G    GE++E+  RRE+ EE GL V++L    
Sbjct: 32  LVLVLQPQRVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGARRELQEESGLTVDALHKVG 91

Query: 262 SQHWPFPSGSLMIACHATVKPGQTEIQVNLRELETAAWFSHDEV 305
              + F     ++  H           V   E+    WF  D++
Sbjct: 92  QIVFEFVGEPELMDVHVFCTDSIQGTPVESDEMR-PCWFQLDQI 134


>gi|40288284 nudix-type motif 1 isoform p18 [Homo sapiens]
          Length = 156

 Score = 36.2 bits (82), Expect = 0.045
 Identities = 27/104 (25%), Positives = 44/104 (42%), Gaps = 2/104 (1%)

Query: 203 ITLVSDGTRCLLA-RQSSFPKGMYSALAGFCDIGESVEETIRREVAEEVGLEVESLQYYA 261
           + LV    R LL  ++  F  G ++   G    GE++E+  RRE+ EE GL V++L    
Sbjct: 9   LVLVLQPQRVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGARRELQEESGLTVDALHKVG 68

Query: 262 SQHWPFPSGSLMIACHATVKPGQTEIQVNLRELETAAWFSHDEV 305
              + F     ++  H           V   E+    WF  D++
Sbjct: 69  QIVFEFVGEPELMDVHVFCTDSIQGTPVESDEMR-PCWFQLDQI 111


>gi|40288282 nudix-type motif 1 isoform p22 [Homo sapiens]
          Length = 179

 Score = 36.2 bits (82), Expect = 0.045
 Identities = 27/104 (25%), Positives = 44/104 (42%), Gaps = 2/104 (1%)

Query: 203 ITLVSDGTRCLLA-RQSSFPKGMYSALAGFCDIGESVEETIRREVAEEVGLEVESLQYYA 261
           + LV    R LL  ++  F  G ++   G    GE++E+  RRE+ EE GL V++L    
Sbjct: 32  LVLVLQPQRVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGARRELQEESGLTVDALHKVG 91

Query: 262 SQHWPFPSGSLMIACHATVKPGQTEIQVNLRELETAAWFSHDEV 305
              + F     ++  H           V   E+    WF  D++
Sbjct: 92  QIVFEFVGEPELMDVHVFCTDSIQGTPVESDEMR-PCWFQLDQI 134


>gi|40288280 nudix-type motif 1 isoform p18 [Homo sapiens]
          Length = 156

 Score = 36.2 bits (82), Expect = 0.045
 Identities = 27/104 (25%), Positives = 44/104 (42%), Gaps = 2/104 (1%)

Query: 203 ITLVSDGTRCLLA-RQSSFPKGMYSALAGFCDIGESVEETIRREVAEEVGLEVESLQYYA 261
           + LV    R LL  ++  F  G ++   G    GE++E+  RRE+ EE GL V++L    
Sbjct: 9   LVLVLQPQRVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGARRELQEESGLTVDALHKVG 68

Query: 262 SQHWPFPSGSLMIACHATVKPGQTEIQVNLRELETAAWFSHDEV 305
              + F     ++  H           V   E+    WF  D++
Sbjct: 69  QIVFEFVGEPELMDVHVFCTDSIQGTPVESDEMR-PCWFQLDQI 111


>gi|40288278 nudix-type motif 1 isoform p22 [Homo sapiens]
          Length = 179

 Score = 36.2 bits (82), Expect = 0.045
 Identities = 27/104 (25%), Positives = 44/104 (42%), Gaps = 2/104 (1%)

Query: 203 ITLVSDGTRCLLA-RQSSFPKGMYSALAGFCDIGESVEETIRREVAEEVGLEVESLQYYA 261
           + LV    R LL  ++  F  G ++   G    GE++E+  RRE+ EE GL V++L    
Sbjct: 32  LVLVLQPQRVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGARRELQEESGLTVDALHKVG 91

Query: 262 SQHWPFPSGSLMIACHATVKPGQTEIQVNLRELETAAWFSHDEV 305
              + F     ++  H           V   E+    WF  D++
Sbjct: 92  QIVFEFVGEPELMDVHVFCTDSIQGTPVESDEMR-PCWFQLDQI 134


>gi|40288276 nudix-type motif 1 isoform p18 [Homo sapiens]
          Length = 156

 Score = 36.2 bits (82), Expect = 0.045
 Identities = 27/104 (25%), Positives = 44/104 (42%), Gaps = 2/104 (1%)

Query: 203 ITLVSDGTRCLLA-RQSSFPKGMYSALAGFCDIGESVEETIRREVAEEVGLEVESLQYYA 261
           + LV    R LL  ++  F  G ++   G    GE++E+  RRE+ EE GL V++L    
Sbjct: 9   LVLVLQPQRVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGARRELQEESGLTVDALHKVG 68

Query: 262 SQHWPFPSGSLMIACHATVKPGQTEIQVNLRELETAAWFSHDEV 305
              + F     ++  H           V   E+    WF  D++
Sbjct: 69  QIVFEFVGEPELMDVHVFCTDSIQGTPVESDEMR-PCWFQLDQI 111


>gi|40288274 nudix-type motif 1 isoform p18 [Homo sapiens]
          Length = 156

 Score = 36.2 bits (82), Expect = 0.045
 Identities = 27/104 (25%), Positives = 44/104 (42%), Gaps = 2/104 (1%)

Query: 203 ITLVSDGTRCLLA-RQSSFPKGMYSALAGFCDIGESVEETIRREVAEEVGLEVESLQYYA 261
           + LV    R LL  ++  F  G ++   G    GE++E+  RRE+ EE GL V++L    
Sbjct: 9   LVLVLQPQRVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGARRELQEESGLTVDALHKVG 68

Query: 262 SQHWPFPSGSLMIACHATVKPGQTEIQVNLRELETAAWFSHDEV 305
              + F     ++  H           V   E+    WF  D++
Sbjct: 69  QIVFEFVGEPELMDVHVFCTDSIQGTPVESDEMR-PCWFQLDQI 111


>gi|20149583 nudix-type motif 6 isoform a [Homo sapiens]
          Length = 316

 Score = 31.6 bits (70), Expect = 1.1
 Identities = 34/145 (23%), Positives = 53/145 (36%), Gaps = 8/145 (5%)

Query: 168 FCSRSGQPTKKNVAGSKRVCPSNNIIYYPQMAPVAITLVSDGTRCLLARQSSFP-KGMYS 226
           FC    +     +    R  PS    Y      VA  +  + TR +L  Q     K M+ 
Sbjct: 113 FCFHHAESDSSTLTLWLREGPSRLPGYASHQVGVAGAVFDESTRKILVVQDRNKLKNMWK 172

Query: 227 ALAGFCDIGESVEETIRREVAEEVGLEVE-----SLQYYASQHWPFPSGSLMIACHATVK 281
              G  +  E + +T  REV EE G++ E     S++   +    F    + I C   +K
Sbjct: 173 FPGGLSEPEEDIGDTAVREVFEETGIKSEFRSVLSIRQQHTNPGAFGKSDMYIICR--LK 230

Query: 282 PGQTEIQVNLRELETAAWFSHDEVA 306
           P    I     E     W   +++A
Sbjct: 231 PYSFTINFCQEECLRCEWMDLNDLA 255


>gi|8922792 nudix-type motif 15 [Homo sapiens]
          Length = 164

 Score = 30.4 bits (67), Expect = 2.5
 Identities = 16/51 (31%), Positives = 27/51 (52%), Gaps = 2/51 (3%)

Query: 211 RCLLA--RQSSFPKGMYSALAGFCDIGESVEETIRREVAEEVGLEVESLQY 259
           RC+L   R+ S   G +    G  + GE+ EE  +RE  EE  L ++++ +
Sbjct: 27  RCVLLGKRKGSVGAGSFQLPGGHLEFGETWEECAQRETWEEAALHLKNVHF 77


>gi|118026927 nudix (nucleoside diphosphate linked moiety X)-type
           motif 18 [Homo sapiens]
          Length = 323

 Score = 30.0 bits (66), Expect = 3.3
 Identities = 14/34 (41%), Positives = 21/34 (61%)

Query: 222 KGMYSALAGFCDIGESVEETIRREVAEEVGLEVE 255
           +G +   AG  + GE++ E ++REV EE GL  E
Sbjct: 68  RGSWYLPAGRMEPGETIVEALQREVKEEAGLHCE 101


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.133    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,219,439
Number of Sequences: 37866
Number of extensions: 549277
Number of successful extensions: 1254
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 1240
Number of HSP's gapped (non-prelim): 12
length of query: 352
length of database: 18,247,518
effective HSP length: 103
effective length of query: 249
effective length of database: 14,347,320
effective search space: 3572482680
effective search space used: 3572482680
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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