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Search of human proteins with 5032041
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5032041 Ras homolog enriched in brain [Homo sapiens]
(184 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5032041 Ras homolog enriched in brain [Homo sapiens] 359 e-100
gi|21389385 Ras homolog enriched in brain like 1 [Homo sapiens] 200 7e-52
gi|38201690 RAP2B, member of RAS oncogene family [Homo sapiens] 135 2e-32
gi|10518344 RAP2A, member of RAS oncogene family [Homo sapiens] 132 1e-31
gi|58219792 RAP1B, member of RAS oncogene family [Homo sapiens] 132 2e-31
gi|7661678 RAP1B, member of RAS oncogene family [Homo sapiens] 132 2e-31
gi|58331202 RAP1A, member of RAS oncogene family [Homo sapiens] 128 2e-30
gi|4506413 RAP1A, member of RAS oncogene family [Homo sapiens] 128 2e-30
gi|32129209 RAP2C, member of RAS oncogene family [Homo sapiens] 127 4e-30
gi|21703367 Di-Ras2 [Homo sapiens] 122 2e-28
gi|5454028 related RAS viral (r-ras) oncogene homolog [Homo sapi... 121 4e-28
gi|33946329 ras related v-ral simian leukemia viral oncogene hom... 119 2e-27
gi|15718761 c-K-ras2 protein isoform b precursor [Homo sapiens] 118 3e-27
gi|21361416 related RAS viral (r-ras) oncogene homolog 2 isoform... 118 3e-27
gi|15718763 c-K-ras2 protein isoform a precursor [Homo sapiens] 117 7e-27
gi|4506533 Ras-like without CAAX 2 [Homo sapiens] 117 7e-27
gi|4505451 neuroblastoma RAS viral (v-ras) oncogene homolog [Hom... 115 3e-26
gi|194363762 v-Ha-ras Harvey rat sarcoma viral oncogene homolog ... 115 3e-26
gi|4885425 v-Ha-ras Harvey rat sarcoma viral oncogene homolog is... 115 3e-26
gi|21553323 DIRAS family, GTP-binding RAS-like 1 [Homo sapiens] 113 8e-26
gi|145386506 muscle RAS oncogene homolog [Homo sapiens] 113 1e-25
gi|145386562 muscle RAS oncogene homolog [Homo sapiens] 113 1e-25
gi|4506405 v-ral simian leukemia viral oncogene homolog B [Homo ... 111 3e-25
gi|34222246 v-Ha-ras Harvey rat sarcoma viral oncogene homolog i... 110 9e-25
gi|5902050 Ras-like without CAAX 1 [Homo sapiens] 108 3e-24
gi|7661922 RAB21, member RAS oncogene family [Homo sapiens] 102 2e-22
gi|11967981 RAB17, member RAS oncogene family [Homo sapiens] 99 2e-21
gi|14249704 RAS-like, estrogen-regulated, growth inhibitor [Homo... 96 1e-20
gi|28376635 RAB37, member RAS oncogene family isoform 3 [Homo sa... 96 2e-20
gi|45592963 RAS-like, family 11, member A [Homo sapiens] 94 5e-20
>gi|5032041 Ras homolog enriched in brain [Homo sapiens]
Length = 184
Score = 359 bits (921), Expect = e-100
Identities = 184/184 (100%), Positives = 184/184 (100%)
Query: 1 MPQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVD 60
MPQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVD
Sbjct: 1 MPQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVD 60
Query: 61 TAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNK 120
TAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNK
Sbjct: 61 TAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNK 120
Query: 121 KDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKMDGAASQGKSS 180
KDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKMDGAASQGKSS
Sbjct: 121 KDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKMDGAASQGKSS 180
Query: 181 CSVM 184
CSVM
Sbjct: 181 CSVM 184
>gi|21389385 Ras homolog enriched in brain like 1 [Homo sapiens]
Length = 183
Score = 200 bits (508), Expect = 7e-52
Identities = 96/184 (52%), Positives = 135/184 (73%), Gaps = 1/184 (0%)
Query: 1 MPQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVD 60
MP + RK+ ILGYR VGK+SL QFVEG+F + YDPT+ENT++K++T+ E+HL LVD
Sbjct: 1 MPLVRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVD 60
Query: 61 TAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNK 120
TAGQDEYSI P ++ I ++GY+LVYSVTS+ SF+VI+ ++ KL + GK ++P++LVGNK
Sbjct: 61 TAGQDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNK 120
Query: 121 KDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKMDGAASQGKSS 180
DL ER + EGK LAESW A F+ESSA+ENQ +F ++I E +++ + Q +
Sbjct: 121 ADLSPEREVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEIARVENSYGQ-ERR 179
Query: 181 CSVM 184
C +M
Sbjct: 180 CHLM 183
>gi|38201690 RAP2B, member of RAS oncogene family [Homo sapiens]
Length = 183
Score = 135 bits (340), Expect = 2e-32
Identities = 66/157 (42%), Positives = 105/157 (66%)
Query: 8 KIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEY 67
K+ +LG VGKS+LT+QFV G F++ YDPTIE+ + K I V+ L+++DTAG +++
Sbjct: 5 KVVVLGSGGVGKSALTVQFVTGSFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQF 64
Query: 68 SIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMER 127
+ Y + G+ILVYS+ + +SF+ IK + +++ + ++P++LVGNK DL ER
Sbjct: 65 ASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYERVPMILVGNKVDLEGER 124
Query: 128 VISYEEGKALAESWNAAFLESSAKENQTAVDVFRRII 164
+SY EGKALAE W+ F+E+SAK + ++F I+
Sbjct: 125 EVSYGEGKALAEEWSCPFMETSAKNKASVDELFAEIV 161
>gi|10518344 RAP2A, member of RAS oncogene family [Homo sapiens]
Length = 183
Score = 132 bits (333), Expect = 1e-31
Identities = 70/181 (38%), Positives = 113/181 (62%), Gaps = 8/181 (4%)
Query: 8 KIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEY 67
K+ +LG VGKS+LT+QFV G F++ YDPTIE+ + K I V+ L+++DTAG +++
Sbjct: 5 KVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQF 64
Query: 68 SIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMER 127
+ Y + G+ILVYS+ + +SF+ IK + +++ + ++P++LVGNK DL ER
Sbjct: 65 ASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDLESER 124
Query: 128 VISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKMDGAASQGK-----SSCS 182
+S EG+ALAE W F+E+SAK ++F I+ +M+ AA K S+C+
Sbjct: 125 EVSSSEGRALAEEWGCPFMETSAKSKTMVDELFAEIV---RQMNYAAQPDKDDPCCSACN 181
Query: 183 V 183
+
Sbjct: 182 I 182
>gi|58219792 RAP1B, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 132 bits (332), Expect = 2e-31
Identities = 70/181 (38%), Positives = 116/181 (64%), Gaps = 5/181 (2%)
Query: 8 KIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEY 67
K+ +LG VGKS+LT+QFV+G FV+ YDPTIE+++ K + V+ Q+ L+++DTAG +++
Sbjct: 5 KLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQF 64
Query: 68 SIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMER 127
+ Y + G+ LVYS+T+ +F ++ + ++L + +P++LVGNK DL ER
Sbjct: 65 TAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDER 124
Query: 128 VISYEEGKALAESW-NAAFLESSAKENQTAVDVFRRIILEAEK---MDGAASQGKSSCSV 183
V+ E+G+ LA W N AFLESSAK ++F ++ + + + G A + KSSC +
Sbjct: 125 VVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARK-KSSCQL 183
Query: 184 M 184
+
Sbjct: 184 L 184
>gi|7661678 RAP1B, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 132 bits (332), Expect = 2e-31
Identities = 70/181 (38%), Positives = 116/181 (64%), Gaps = 5/181 (2%)
Query: 8 KIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEY 67
K+ +LG VGKS+LT+QFV+G FV+ YDPTIE+++ K + V+ Q+ L+++DTAG +++
Sbjct: 5 KLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQF 64
Query: 68 SIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMER 127
+ Y + G+ LVYS+T+ +F ++ + ++L + +P++LVGNK DL ER
Sbjct: 65 TAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDER 124
Query: 128 VISYEEGKALAESW-NAAFLESSAKENQTAVDVFRRIILEAEK---MDGAASQGKSSCSV 183
V+ E+G+ LA W N AFLESSAK ++F ++ + + + G A + KSSC +
Sbjct: 125 VVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARK-KSSCQL 183
Query: 184 M 184
+
Sbjct: 184 L 184
>gi|58331202 RAP1A, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 128 bits (322), Expect = 2e-30
Identities = 64/163 (39%), Positives = 106/163 (65%), Gaps = 1/163 (0%)
Query: 8 KIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEY 67
K+ +LG VGKS+LT+QFV+G FV+ YDPTIE+++ K + V+ Q+ L+++DTAG +++
Sbjct: 5 KLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGTEQF 64
Query: 68 SIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMER 127
+ Y + G+ LVYS+T+ +F ++ + ++L + +P++LVGNK DL ER
Sbjct: 65 TAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLEDER 124
Query: 128 VISYEEGKALAESW-NAAFLESSAKENQTAVDVFRRIILEAEK 169
V+ E+G+ LA W N AFLESSAK ++F ++ + +
Sbjct: 125 VVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINR 167
>gi|4506413 RAP1A, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 128 bits (322), Expect = 2e-30
Identities = 64/163 (39%), Positives = 106/163 (65%), Gaps = 1/163 (0%)
Query: 8 KIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEY 67
K+ +LG VGKS+LT+QFV+G FV+ YDPTIE+++ K + V+ Q+ L+++DTAG +++
Sbjct: 5 KLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGTEQF 64
Query: 68 SIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMER 127
+ Y + G+ LVYS+T+ +F ++ + ++L + +P++LVGNK DL ER
Sbjct: 65 TAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLEDER 124
Query: 128 VISYEEGKALAESW-NAAFLESSAKENQTAVDVFRRIILEAEK 169
V+ E+G+ LA W N AFLESSAK ++F ++ + +
Sbjct: 125 VVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINR 167
>gi|32129209 RAP2C, member of RAS oncogene family [Homo sapiens]
Length = 183
Score = 127 bits (320), Expect = 4e-30
Identities = 62/157 (39%), Positives = 101/157 (64%)
Query: 8 KIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEY 67
K+ +LG VGKS+LT+QFV G F++ YDPTIE+ + K I V+ L+++DTAG +++
Sbjct: 5 KVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQF 64
Query: 68 SIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMER 127
+ Y + G+ILVYS+ + +SF+ IK + +++ + ++P++LVGNK DL ER
Sbjct: 65 ASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDLEPER 124
Query: 128 VISYEEGKALAESWNAAFLESSAKENQTAVDVFRRII 164
+ EG+ALA+ W F+E+SAK ++F I+
Sbjct: 125 EVMSSEGRALAQEWGCPFMETSAKSKSMVDELFAEIV 161
>gi|21703367 Di-Ras2 [Homo sapiens]
Length = 199
Score = 122 bits (306), Expect = 2e-28
Identities = 68/180 (37%), Positives = 108/180 (60%), Gaps = 2/180 (1%)
Query: 3 QSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTA 62
QS ++A+ G VGKSSL ++FV+G F +SY PT+E+T+ ++I+ + LQ+ DT
Sbjct: 4 QSNDYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTT 63
Query: 63 GQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQ-IPIMLVGNKK 121
G ++ + + +ILVYS+TS +S E +K I+ ++ ++ G V+ IPIMLVGNK
Sbjct: 64 GSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPIMLVGNKC 123
Query: 122 DLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRII-LEAEKMDGAASQGKSS 180
D R + E +ALA +W AF+E+SAK N ++F+ ++ LE + GK S
Sbjct: 124 DESPSREVQSSEAEALARTWKCAFMETSAKLNHNVKELFQELLNLEKRRTVSLQIDGKKS 183
>gi|5454028 related RAS viral (r-ras) oncogene homolog [Homo
sapiens]
Length = 218
Score = 121 bits (303), Expect = 4e-28
Identities = 58/168 (34%), Positives = 101/168 (60%)
Query: 2 PQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDT 61
P S++ K+ ++G VGKS+LTIQF++ FV YDPTIE+++TK+ +V+G L ++DT
Sbjct: 25 PPSETHKLVVVGGGGVGKSALTIQFIQSYFVSDYDPTIEDSYTKICSVDGIPARLDILDT 84
Query: 62 AGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKK 121
AGQ+E+ + Y +G++LV+++ +SF + + ++L + + P++LVGNK
Sbjct: 85 AGQEEFGAMREQYMRAGHGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPVVLVGNKA 144
Query: 122 DLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEK 169
DL +R + E A S + A+ E+SAK + F +++ K
Sbjct: 145 DLESQRQVPRSEASAFGASHHVAYFEASAKLRLNVDEAFEQLVRAVRK 192
>gi|33946329 ras related v-ral simian leukemia viral oncogene
homolog A [Homo sapiens]
Length = 206
Score = 119 bits (297), Expect = 2e-27
Identities = 62/174 (35%), Positives = 102/174 (58%), Gaps = 3/174 (1%)
Query: 8 KIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEY 67
K+ ++G VGKS+LT+QF+ +FV+ Y+PT +++ K + ++G+E + ++DTAGQ++Y
Sbjct: 16 KVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDY 75
Query: 68 SIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMER 127
+ Y G++ V+S+T ++SF ++L + +P +LVGNK DL +R
Sbjct: 76 AAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILRVKEDENVPFLLVGNKSDLEDKR 135
Query: 128 VISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILE--AEKM-DGAASQGK 178
+S EE K AE WN ++E+SAK VF ++ E A KM D GK
Sbjct: 136 QVSVEEAKNRAEQWNVNYVETSAKTRANVDKVFFDLMREIRARKMEDSKEKNGK 189
>gi|15718761 c-K-ras2 protein isoform b precursor [Homo sapiens]
Length = 188
Score = 118 bits (296), Expect = 3e-27
Identities = 66/185 (35%), Positives = 105/185 (56%), Gaps = 9/185 (4%)
Query: 8 KIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEY 67
K+ ++G VGKS+LTIQ ++ FVD YDPTIE+++ K + ++G+ L ++DTAGQ+EY
Sbjct: 5 KLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEY 64
Query: 68 SIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMER 127
S Y G++ V+++ + KSFE I ++ + +P++LVGNK DL R
Sbjct: 65 SAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL-PSR 123
Query: 128 VISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEK------MDGAASQGKS-- 179
+ ++ + LA S+ F+E+SAK Q D F ++ E K DG + KS
Sbjct: 124 TVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEKMSKDGKKKKKKSKT 183
Query: 180 SCSVM 184
C +M
Sbjct: 184 KCVIM 188
>gi|21361416 related RAS viral (r-ras) oncogene homolog 2 isoform a
[Homo sapiens]
Length = 204
Score = 118 bits (295), Expect = 3e-27
Identities = 57/157 (36%), Positives = 95/157 (60%)
Query: 8 KIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEY 67
++ ++G VGKS+LTIQF++ FV YDPTIE+++TK ++ + L ++DTAGQ+E+
Sbjct: 16 RLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDRAARLDILDTAGQEEF 75
Query: 68 SIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMER 127
+ Y G++LV+SVT SFE I ++L + + + P++L+GNK DL +R
Sbjct: 76 GAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDHQR 135
Query: 128 VISYEEGKALAESWNAAFLESSAKENQTAVDVFRRII 164
++ EEG+ LA ++E+SAK F ++
Sbjct: 136 QVTQEEGQQLARQLKVTYMEASAKIRMNVDQAFHELV 172
>gi|15718763 c-K-ras2 protein isoform a precursor [Homo sapiens]
Length = 189
Score = 117 bits (292), Expect = 7e-27
Identities = 59/159 (37%), Positives = 96/159 (60%), Gaps = 1/159 (0%)
Query: 8 KIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEY 67
K+ ++G VGKS+LTIQ ++ FVD YDPTIE+++ K + ++G+ L ++DTAGQ+EY
Sbjct: 5 KLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEY 64
Query: 68 SIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMER 127
S Y G++ V+++ + KSFE I ++ + +P++LVGNK DL R
Sbjct: 65 SAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL-PSR 123
Query: 128 VISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILE 166
+ ++ + LA S+ F+E+SAK Q D F ++ E
Sbjct: 124 TVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVRE 162
>gi|4506533 Ras-like without CAAX 2 [Homo sapiens]
Length = 217
Score = 117 bits (292), Expect = 7e-27
Identities = 61/172 (35%), Positives = 98/172 (56%)
Query: 4 SKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAG 63
S+ K+ +LG VGKS++T+QF+ QF D +DPTIE+ + + ++ + +L ++DTAG
Sbjct: 18 SREYKVVMLGAGGVGKSAMTMQFISHQFPDYHDPTIEDAYKTQVRIDNEPAYLDILDTAG 77
Query: 64 QDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDL 123
Q E++ + Y G+I+ YSVT +SF+ + + +IP++LVGNK DL
Sbjct: 78 QAEFTAMREQYMRGGEGFIICYSVTDRQSFQEAAKFKELIFQVRHTYEIPLVLVGNKIDL 137
Query: 124 HMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKMDGAAS 175
R +S EEG +LA+ +N F E+SA D F ++ E K + S
Sbjct: 138 EQFRQVSTEEGLSLAQEYNCGFFETSAALRFCIDDAFHGLVREIRKKESMPS 189
>gi|4505451 neuroblastoma RAS viral (v-ras) oncogene homolog [Homo
sapiens]
Length = 189
Score = 115 bits (287), Expect = 3e-26
Identities = 58/159 (36%), Positives = 96/159 (60%), Gaps = 1/159 (0%)
Query: 8 KIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEY 67
K+ ++G VGKS+LTIQ ++ FVD YDPTIE+++ K + ++G+ L ++DTAGQ+EY
Sbjct: 5 KLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEY 64
Query: 68 SIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMER 127
S Y G++ V+++ + KSF I + ++ + +P++LVGNK DL R
Sbjct: 65 SAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDL-PTR 123
Query: 128 VISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILE 166
+ ++ LA+S+ F+E+SAK Q D F ++ E
Sbjct: 124 TVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVRE 162
>gi|194363762 v-Ha-ras Harvey rat sarcoma viral oncogene homolog
isoform 1 [Homo sapiens]
Length = 189
Score = 115 bits (287), Expect = 3e-26
Identities = 58/159 (36%), Positives = 95/159 (59%), Gaps = 1/159 (0%)
Query: 8 KIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEY 67
K+ ++G VGKS+LTIQ ++ FVD YDPTIE+++ K + ++G+ L ++DTAGQ+EY
Sbjct: 5 KLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEY 64
Query: 68 SIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMER 127
S Y G++ V+++ + KSFE I ++ + +P++LVGNK DL R
Sbjct: 65 SAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL-AAR 123
Query: 128 VISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILE 166
+ + + LA S+ ++E+SAK Q D F ++ E
Sbjct: 124 TVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVRE 162
>gi|4885425 v-Ha-ras Harvey rat sarcoma viral oncogene homolog
isoform 1 [Homo sapiens]
Length = 189
Score = 115 bits (287), Expect = 3e-26
Identities = 58/159 (36%), Positives = 95/159 (59%), Gaps = 1/159 (0%)
Query: 8 KIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEY 67
K+ ++G VGKS+LTIQ ++ FVD YDPTIE+++ K + ++G+ L ++DTAGQ+EY
Sbjct: 5 KLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEY 64
Query: 68 SIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMER 127
S Y G++ V+++ + KSFE I ++ + +P++LVGNK DL R
Sbjct: 65 SAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL-AAR 123
Query: 128 VISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILE 166
+ + + LA S+ ++E+SAK Q D F ++ E
Sbjct: 124 TVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVRE 162
>gi|21553323 DIRAS family, GTP-binding RAS-like 1 [Homo sapiens]
Length = 198
Score = 113 bits (283), Expect = 8e-26
Identities = 65/180 (36%), Positives = 106/180 (58%), Gaps = 3/180 (1%)
Query: 3 QSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTA 62
QS ++ + G VGKSSL ++FV+G F D+Y PTIE+T+ ++I+ + LQ+ DT
Sbjct: 4 QSNDYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTIEDTYRQVISCDKSVCTLQITDTT 63
Query: 63 GQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQ-IPIMLVGNKK 121
G ++ + + +ILV+SVTS +S E + I+ ++ + G V+ IP+MLVGNK
Sbjct: 64 GSHQFPAMQRLSISKGHAFILVFSVTSKQSLEELGPIYKLIVQIKGSVEDIPVMLVGNKC 123
Query: 122 DLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRII-LEAEKMDGAASQGKSS 180
D +R + E +A+A+ W AF+E+SAK N ++F+ ++ LE + GK S
Sbjct: 124 D-ETQREVDTREAQAVAQEWKCAFMETSAKMNYNVKELFQELLTLETRRNMSLNIDGKRS 182
>gi|145386506 muscle RAS oncogene homolog [Homo sapiens]
Length = 208
Score = 113 bits (282), Expect = 1e-25
Identities = 61/151 (40%), Positives = 93/151 (61%)
Query: 8 KIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEY 67
K+ ++G VGKS+LTIQF + FV YDPTIE+++ K ++ Q L ++DTAGQ+E+
Sbjct: 15 KLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQWAILDVLDTAGQEEF 74
Query: 68 SIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMER 127
S + Y +G+++VYSVT SFE + H +L + + P++LV NK DL R
Sbjct: 75 SAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDLMHLR 134
Query: 128 VISYEEGKALAESWNAAFLESSAKENQTAVD 158
I+ E+GK +A N ++E+SAK+ VD
Sbjct: 135 KITREQGKEMATKHNIPYIETSAKDPPLNVD 165
>gi|145386562 muscle RAS oncogene homolog [Homo sapiens]
Length = 208
Score = 113 bits (282), Expect = 1e-25
Identities = 61/151 (40%), Positives = 93/151 (61%)
Query: 8 KIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEY 67
K+ ++G VGKS+LTIQF + FV YDPTIE+++ K ++ Q L ++DTAGQ+E+
Sbjct: 15 KLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQWAILDVLDTAGQEEF 74
Query: 68 SIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMER 127
S + Y +G+++VYSVT SFE + H +L + + P++LV NK DL R
Sbjct: 75 SAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDLMHLR 134
Query: 128 VISYEEGKALAESWNAAFLESSAKENQTAVD 158
I+ E+GK +A N ++E+SAK+ VD
Sbjct: 135 KITREQGKEMATKHNIPYIETSAKDPPLNVD 165
>gi|4506405 v-ral simian leukemia viral oncogene homolog B [Homo
sapiens]
Length = 206
Score = 111 bits (278), Expect = 3e-25
Identities = 54/160 (33%), Positives = 97/160 (60%), Gaps = 1/160 (0%)
Query: 8 KIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEY 67
K+ ++G VGKS+LT+QF+ +FV+ Y+PT +++ K + ++G+E + ++DTAGQ++Y
Sbjct: 16 KVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDY 75
Query: 68 SIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKV-QIPIMLVGNKKDLHME 126
+ Y G++LV+S+T +SF ++L + + +IP+++VGNK DL
Sbjct: 76 AAIRDNYFRSGEGFLLVFSITEHESFTATAEFREQILRVKAEEDKIPLLVVGNKSDLEER 135
Query: 127 RVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILE 166
R + EE ++ AE W ++E+SAK VF ++ E
Sbjct: 136 RQVPVEEARSKAEEWGVQYVETSAKTRANVDKVFFDLMRE 175
>gi|34222246 v-Ha-ras Harvey rat sarcoma viral oncogene homolog
isoform 2 [Homo sapiens]
Length = 170
Score = 110 bits (274), Expect = 9e-25
Identities = 55/147 (37%), Positives = 90/147 (61%), Gaps = 1/147 (0%)
Query: 8 KIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEY 67
K+ ++G VGKS+LTIQ ++ FVD YDPTIE+++ K + ++G+ L ++DTAGQ+EY
Sbjct: 5 KLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEY 64
Query: 68 SIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMER 127
S Y G++ V+++ + KSFE I ++ + +P++LVGNK DL R
Sbjct: 65 SAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL-AAR 123
Query: 128 VISYEEGKALAESWNAAFLESSAKENQ 154
+ + + LA S+ ++E+SAK Q
Sbjct: 124 TVESRQAQDLARSYGIPYIETSAKTRQ 150
>gi|5902050 Ras-like without CAAX 1 [Homo sapiens]
Length = 219
Score = 108 bits (269), Expect = 3e-24
Identities = 57/171 (33%), Positives = 96/171 (56%)
Query: 4 SKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAG 63
S+ K+ +LG VGKS++T+QF+ +F + +DPTIE+ + I ++ + +L ++DTAG
Sbjct: 19 SREYKLVMLGAGGVGKSAMTMQFISHRFPEDHDPTIEDAYKIRIRIDDEPANLDILDTAG 78
Query: 64 QDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDL 123
Q E++ Y G+I+ YS+T +SF ++ + + P++LVGNK DL
Sbjct: 79 QAEFTAMRDQYMRAGEGFIICYSITDRRSFHEVREFKQLIYRVRRTDDTPVVLVGNKSDL 138
Query: 124 HMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKMDGAA 174
R ++ EEG ALA ++ F E+SA DVF ++ E + + A
Sbjct: 139 KQLRQVTKEEGLALAREFSCPFFETSAAYRYYIDDVFHALVREIRRKEKEA 189
>gi|7661922 RAB21, member RAS oncogene family [Homo sapiens]
Length = 225
Score = 102 bits (254), Expect = 2e-22
Identities = 64/179 (35%), Positives = 103/179 (57%), Gaps = 6/179 (3%)
Query: 6 SRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTF-TKLITVNGQEYHLQLVDTAGQ 64
S K+ +LG VGK+SL +++ E +F D + T++ +F TK + + G+ +L + DTAGQ
Sbjct: 19 SFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQ 78
Query: 65 DEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLH 124
+ + Y D NG ILVY +T SF+ +K +L M+G +I + +VGNK DL
Sbjct: 79 ERFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLGN-EICLCIVGNKIDLE 137
Query: 125 MERVISYEEGKALAESWNAAFLESSAKEN----QTAVDVFRRIILEAEKMDGAASQGKS 179
ER +S +E ++ AES A +SAK+N + +D+ +R+I A+ + A G S
Sbjct: 138 KERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQVDERAKGNGSS 196
>gi|11967981 RAB17, member RAS oncogene family [Homo sapiens]
Length = 212
Score = 99.0 bits (245), Expect = 2e-21
Identities = 63/185 (34%), Positives = 102/185 (55%), Gaps = 5/185 (2%)
Query: 3 QSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTF-TKLITVNGQEYHLQLVDT 61
Q + K+ +LG SVGKSSL +++V+ F S PT+ F TK++ V L++ DT
Sbjct: 16 QPRVFKLVLLGSGSVGKSSLALRYVKNDF-KSILPTVGCAFFTKVVDVGATSLKLEIWDT 74
Query: 62 AGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKK 121
AGQ++Y Y N +LVY +T SF + L + + ++ +MLVGNK
Sbjct: 75 AGQEKYHSVCHLYFRGANAALLVYDITRKDSFLKAQQWLKDLEEELHPGEVLVMLVGNKT 134
Query: 122 DLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRI---ILEAEKMDGAASQGK 178
DL ER ++++EGK A+S F+E+SAK N +VF + +L+ +G A +G
Sbjct: 135 DLSQEREVTFQEGKEFADSQKLLFMETSAKLNHQVSEVFNTVAQELLQRSDEEGQALRGD 194
Query: 179 SSCSV 183
++ ++
Sbjct: 195 AAVAL 199
>gi|14249704 RAS-like, estrogen-regulated, growth inhibitor [Homo
sapiens]
Length = 199
Score = 96.3 bits (238), Expect = 1e-20
Identities = 54/150 (36%), Positives = 89/150 (59%), Gaps = 1/150 (0%)
Query: 1 MPQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVD 60
M +S K+AI G VGKS+L ++F+ +F+ YDPT+E+T+ T++ + ++++D
Sbjct: 1 MAKSAEVKLAIFGRAGVGKSALVVRFLTKRFIWEYDPTLESTYRHQATIDDEVVSMEILD 60
Query: 61 TAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNK 120
TAGQ++ +I + + G++LVY +T SFE + + L ++ + ++LVGNK
Sbjct: 61 TAGQED-TIQREGHMRWGEGFVLVYDITDRGSFEEVLPLKNILDEIKKPKNVTLILVGNK 119
Query: 121 KDLHMERVISYEEGKALAESWNAAFLESSA 150
DL R +S EEG+ LA AF E SA
Sbjct: 120 ADLDHSRQVSTEEGEKLATELACAFYECSA 149
>gi|28376635 RAB37, member RAS oncogene family isoform 3 [Homo
sapiens]
Length = 216
Score = 95.9 bits (237), Expect = 2e-20
Identities = 59/167 (35%), Positives = 92/167 (55%), Gaps = 3/167 (1%)
Query: 8 KIAILGYRSVGKSSLTIQFVEGQFVD-SYDPTIENTFT-KLITVNGQEYHLQLVDTAGQD 65
K ++G VGK+SL +QF +G+F+ S+ T+ FT K++TV+G LQ+ DTAGQ+
Sbjct: 24 KTILVGDSGVGKTSLLVQFDQGKFIPGSFSATVGIGFTNKVVTVDGVRVKLQIWDTAGQE 83
Query: 66 EYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHM 125
+ Y D +L+Y +T+ SF+ I+ ++ + + + IML+GNK D+
Sbjct: 84 RFRSVTHAYYRDAQALLLLYDITNKSSFDNIRAWLTEIHEYAQR-DVVIMLLGNKADMSS 142
Query: 126 ERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKMDG 172
ERVI E+G+ LA + FLE+SAK F I E + G
Sbjct: 143 ERVIRSEDGETLAREYGVPFLETSAKTGMNVELAFLAIAKELKYRAG 189
>gi|45592963 RAS-like, family 11, member A [Homo sapiens]
Length = 242
Score = 94.4 bits (233), Expect = 5e-20
Identities = 56/180 (31%), Positives = 96/180 (53%), Gaps = 8/180 (4%)
Query: 5 KSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAG- 63
K K+A+LG VGKS++ ++F+ +F+ Y+P +++L+ V G + LQ+ DT G
Sbjct: 26 KDIKLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNTGKLYSRLVYVEGDQLSLQIQDTPGG 85
Query: 64 ---QDEYSIFPQTYSIDI---NGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLV 117
QD + S + G++LVYS+T S+ I+ ++ + + + P+++V
Sbjct: 86 VQIQDSLPQVVDSLSKCVQWAEGFLLVYSITDYDSYLSIRPLYQHIRKVHPDSKAPVIIV 145
Query: 118 GNKKDLHMERVISYEEGKALAESWNAAFLESSAKEN-QTAVDVFRRIILEAEKMDGAASQ 176
GNK DL R + ++G LA + FLE S EN + DVF+ + E KM G + +
Sbjct: 146 GNKGDLLHARQVQTQDGIQLANELGSLFLEISTSENYEDVCDVFQHLCKEVSKMHGLSGE 205
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.362
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,752,556
Number of Sequences: 37866
Number of extensions: 208257
Number of successful extensions: 866
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 171
Number of HSP's successfully gapped in prelim test: 46
Number of HSP's that attempted gapping in prelim test: 509
Number of HSP's gapped (non-prelim): 227
length of query: 184
length of database: 18,247,518
effective HSP length: 96
effective length of query: 88
effective length of database: 14,612,382
effective search space: 1285889616
effective search space used: 1285889616
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.