BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4885335 G protein-coupled receptor 4 [Homo sapiens] (362 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4885335 G protein-coupled receptor 4 [Homo sapiens] 748 0.0 gi|40217829 G protein-coupled receptor 68 [Homo sapiens] 327 1e-89 gi|33695104 G protein-coupled receptor 65 [Homo sapiens] 237 1e-62 gi|7019387 G protein-coupled receptor 132 [Homo sapiens] 197 2e-50 gi|31083344 chemokine orphan receptor 1 [Homo sapiens] 153 3e-37 gi|241982708 G-protein coupled purinergic receptor P2Y5 [Homo sa... 148 8e-36 gi|241982706 G-protein coupled purinergic receptor P2Y5 [Homo sa... 148 8e-36 gi|33695113 G-protein coupled purinergic receptor P2Y5 [Homo sap... 148 8e-36 gi|4506241 platelet-activating factor receptor [Homo sapiens] 148 8e-36 gi|4885311 lysophosphatidic acid receptor 4 [Homo sapiens] 146 2e-35 gi|34577052 coagulation factor II (thrombin) receptor-like 1 pre... 145 4e-35 gi|238814307 G protein-coupled receptor 17 isoform b [Homo sapiens] 145 4e-35 gi|238814305 G protein-coupled receptor 17 isoform b [Homo sapiens] 145 4e-35 gi|4885301 G protein-coupled receptor 17 isoform a [Homo sapiens] 145 4e-35 gi|238814302 G protein-coupled receptor 17 isoform a [Homo sapiens] 145 4e-35 gi|4505557 purinergic receptor P2Y1 [Homo sapiens] 143 2e-34 gi|4502631 chemokine (C-C motif) receptor 1 [Homo sapiens] 137 1e-32 gi|5031627 chemokine (C-C motif) receptor 4 [Homo sapiens] 135 6e-32 gi|52426789 oxoglutarate (alpha-ketoglutarate) receptor 1 [Homo ... 135 7e-32 gi|28872720 purinergic receptor P2Y2 [Homo sapiens] 134 1e-31 gi|28872745 purinergic receptor P2Y2 [Homo sapiens] 134 1e-31 gi|28872743 purinergic receptor P2Y2 [Homo sapiens] 134 1e-31 gi|4826706 EBV-induced G protein-coupled receptor 2 [Homo sapiens] 134 1e-31 gi|219281887 lysophosphatidic acid receptor 5 [Homo sapiens] 134 2e-31 gi|9966879 lysophosphatidic acid receptor 5 [Homo sapiens] 134 2e-31 gi|30581170 CC chemokine receptor 3 [Homo sapiens] 130 2e-30 gi|4502637 CC chemokine receptor 3 [Homo sapiens] 130 2e-30 gi|4505561 pyrimidinergic receptor P2Y4 [Homo sapiens] 130 2e-30 gi|4758326 coagulation factor II (thrombin) receptor-like 2 prec... 127 2e-29 gi|4885057 apelin receptor [Homo sapiens] 125 8e-29 >gi|4885335 G protein-coupled receptor 4 [Homo sapiens] Length = 362 Score = 748 bits (1930), Expect = 0.0 Identities = 362/362 (100%), Positives = 362/362 (100%) Query: 1 MGNHTWEGCHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLS 60 MGNHTWEGCHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLS Sbjct: 1 MGNHTWEGCHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLS 60 Query: 61 IADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVA 120 IADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVA Sbjct: 61 IADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVA 120 Query: 121 HPLRFARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHTFCFEKFPMEGWVAW 180 HPLRFARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHTFCFEKFPMEGWVAW Sbjct: 121 HPLRFARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHTFCFEKFPMEGWVAW 180 Query: 181 MNLYRVFVGFLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVLVCFAPY 240 MNLYRVFVGFLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVLVCFAPY Sbjct: 181 MNLYRVFVGFLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVLVCFAPY 240 Query: 241 HVLLLSRSAIYLGRPWDCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDVAKA 300 HVLLLSRSAIYLGRPWDCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDVAKA Sbjct: 241 HVLLLSRSAIYLGRPWDCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDVAKA 300 Query: 301 LHNLLRFLASDKPQEMANASLTLETPLTSKRNSTAKAMTGSWAATPPSQGDQVQLKMLPP 360 LHNLLRFLASDKPQEMANASLTLETPLTSKRNSTAKAMTGSWAATPPSQGDQVQLKMLPP Sbjct: 301 LHNLLRFLASDKPQEMANASLTLETPLTSKRNSTAKAMTGSWAATPPSQGDQVQLKMLPP 360 Query: 361 AQ 362 AQ Sbjct: 361 AQ 362 >gi|40217829 G protein-coupled receptor 68 [Homo sapiens] Length = 375 Score = 327 bits (838), Expect = 1e-89 Identities = 162/318 (50%), Positives = 205/318 (64%), Gaps = 12/318 (3%) Query: 1 MGNHTWEG----CHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYL 56 MGN T + C +D + P +Y+ V+ VG P NCL+L+ Y Q++ RNELGVYL Sbjct: 11 MGNITADNSSMSCTIDHTIHQTLAPVVYVTVLVVGFPANCLSLYFGYLQIKARNELGVYL 70 Query: 57 MNLSIADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRY 116 NL++ADL YIC+LP W+ Y L HDNW HG SC++ G + Y NIYIS+ FLCCISVDRY Sbjct: 71 CNLTVADLFYICSLPFWLQYVLQHDNWSHGDLSCQVCGILLYENIYISVGFLCCISVDRY 130 Query: 117 LAVAHPLRFARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHTFCFEKFPMEG 176 LAVAHP RF + R +K AV VS V+WA EL + L H+E+ D H CFE +P++ Sbjct: 131 LAVAHPFRFHQFRTLKAAVGVSVVIWAKELLTSIYFLMHEEVIEDENQHRVCFEHYPIQA 190 Query: 177 WVAWMNLYRVFVGFLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVLVC 236 W +N YR VGFLFP L+L SY+GILRAVR S T++ K +I+RL LS + I L C Sbjct: 191 WQRAINYYRFLVGFLFPICLLLASYQGILRAVRRSHGTQKSRKDQIQRLVLSTVVIFLAC 250 Query: 237 FAPYHVLLLSRSAIYLGRPWD--CGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGAR 294 F PYHVLLL RS W+ C F + VF+AYH SL TS NCVADP+LYC V+E Sbjct: 251 FLPYHVLLLVRSV------WEASCDFAKGVFNAYHFSLLLTSFNCVADPVLYCFVSETTH 304 Query: 295 SDVAKALHNLLRFLASDK 312 D+A+ L FL + Sbjct: 305 RDLARLRGACLAFLTCSR 322 >gi|33695104 G protein-coupled receptor 65 [Homo sapiens] Length = 337 Score = 237 bits (605), Expect = 1e-62 Identities = 123/300 (41%), Positives = 182/300 (60%), Gaps = 11/300 (3%) Query: 15 VDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLSIADLLYICTLPLWV 74 +DH P +YIFVI V +P N +L ++ Q ++ +ELG+YL +LS++DLLY TLPLW+ Sbjct: 12 LDHYLFPIVYIFVIIVSIPANIGSLCVSFLQAKKESELGIYLFSLSLSDLLYALTLPLWI 71 Query: 75 DYFLHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVAHPLRFARLRRVKTA 134 DY + DNW P CK F+ Y N Y S AFL CI+VDRYLAV +PL+F LR + A Sbjct: 72 DYTWNKDNWTFSPALCKGSAFLMYMNFYSSTAFLTCIAVDRYLAVVYPLKFFFLRTRRFA 131 Query: 135 VAVSSVVWATELGANSAPLFHDELF-----RDRYNHTFCFEKFPMEGWVAWMNLYRVFVG 189 + VS +W E N+ L+ DE ++ N T C++K+P+E W +NL+R G Sbjct: 132 LMVSLSIWILETIFNAVMLWEDETVVEYCDAEKSNFTLCYDKYPLEKWQINLNLFRTCTG 191 Query: 190 FLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVLVCFAPYHVLLLSRSA 249 + P +L+ R + +AVR + +TE +EK +I +L +S+ ++CF P+HV+LL R Sbjct: 192 YAIPLVTILICNRKVYQAVRHNKATENKEKKRIIKLLVSITVTFVLCFTPFHVMLLIRCI 251 Query: 250 IYLGRPWD--CGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDVAKALHNLLRF 307 + ++ +R ++ Y ++A TSLNCVADPILYC V E R D + N+L+F Sbjct: 252 LEHAVNFEDHSNSGKRTYTMYRITVALTSLNCVADPILYCFVTETGRYD----MWNILKF 307 >gi|7019387 G protein-coupled receptor 132 [Homo sapiens] Length = 380 Score = 197 bits (500), Expect = 2e-50 Identities = 106/281 (37%), Positives = 165/281 (58%), Gaps = 11/281 (3%) Query: 23 LYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLSIADLLYICTLPLWVDYFLHHDN 82 +Y V +G+P NCL W A QV Q N L VYL+ L++ +LLY TLPLWV Y + Sbjct: 48 VYSAVCTLGVPANCLTAWLALLQVLQGNVLAVYLLCLALCELLYTGTLPLWVIYIRNQHR 107 Query: 83 WIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVAHPLRFARLRRVKTAVAVSSVVW 142 W G +CK+ +IF+ NIY+SI FLCCIS DR++AV + L RR +TA+ +S+ ++ Sbjct: 108 WTLGLLACKVTAYIFFCNIYVSILFLCCISCDRFVAVVYALESRGRRRRRTAILISACIF 167 Query: 143 ATELGANSAPLFHDELFRDRYNHTFCFEKFPMEGWVAWMNLYRVFVGFLFPWALMLLSYR 202 +G P+F E + CF+ M+ +A R VGF P +++ + Sbjct: 168 IL-VGIVHYPVFQTE------DKETCFDMLQMDSRIAGYYYARFTVGFAIPLSIIAFTNH 220 Query: 203 GILRAVRGSVSTERQEKAKIKRLALSLIAIVLVCFAPYHVLLLSRSAIYLGRPWD----C 258 I R+++ S+ +KAK+K A++++ I LVCFAPYH++LL ++A + D C Sbjct: 221 RIFRSIKQSMGLSAAQKAKVKHSAIAVVVIFLVCFAPYHLVLLVKAAAFSYYRGDRNAMC 280 Query: 259 GFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDVAK 299 G EER+++A L +++N VADPI+Y L + +R +V++ Sbjct: 281 GLEERLYTASVVFLCLSTVNGVADPIIYVLATDHSRQEVSR 321 >gi|31083344 chemokine orphan receptor 1 [Homo sapiens] Length = 362 Score = 153 bits (386), Expect = 3e-37 Identities = 90/317 (28%), Positives = 162/317 (51%), Gaps = 10/317 (3%) Query: 23 LYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLSIADLLYICTLPLWVDYFLHHDN 82 +YIF+ +G+ N + +W + + Y++NL+IADL + T+P+WV + H+ Sbjct: 50 IYIFIFVIGMIANSVVVWVNIQAKTTGYDTHCYILNLAIADLWVVLTIPVWVVSLVQHNQ 109 Query: 83 WIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVAHPLRFARLRRVKTAVAVSSVVW 142 W G +CK+ IF N++ SI FL C+SVDRYL++ + R+ V +VW Sbjct: 110 WPMGELTCKVTHLIFSINLFGSIFFLTCMSVDRYLSITYFTNTPSSRKKMVRRVVCILVW 169 Query: 143 ATELGANSAPLFHDELFRDRYNH-TFCFEKFP---MEGWVAWMNLYRVFVGFLFPWALML 198 + ++ + N+ T+C +P ++ W+ M L V +GF P++++ Sbjct: 170 LLAFCVSLPDTYYLKTVTSASNNETYCRSFYPEHSIKEWLIGMELVSVVLGFAVPFSIIA 229 Query: 199 LSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVLVCFAPYHV-LLLSRSAIYLGRPWD 257 + Y + RA+ S QEK +++ S + + LVC+ PYHV +LL +I P+ Sbjct: 230 VFYFLLARAISAS---SDQEKHSSRKIIFSYVVVFLVCWLPYHVAVLLDIFSILHYIPFT 286 Query: 258 CGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDVAKALHNLLRFLASDKPQEMA 317 C E +F+A H + + ++C +P+LY +N R ++ KA + ++ A ++ Sbjct: 287 CRLEHALFTALHVTQCLSLVHCCVNPVLYSFINRNYRYELMKAF--IFKYSAKTGLTKLI 344 Query: 318 NASLTLETPLTSKRNST 334 +AS ET ++ ST Sbjct: 345 DASRVSETEYSALEQST 361 >gi|241982708 G-protein coupled purinergic receptor P2Y5 [Homo sapiens] Length = 344 Score = 148 bits (373), Expect = 8e-36 Identities = 87/281 (30%), Positives = 145/281 (51%), Gaps = 7/281 (2%) Query: 23 LYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLSIADLLYICTLPLWVDYFLHHDN 82 ++ V +GL +NC+A++ ++ RNE Y++NL+++DLL++ TLP + YF N Sbjct: 23 MFSMVFVLGLISNCVAIYIFICVLKVRNETTTYMINLAMSDLLFVFTLPFRIFYFTTR-N 81 Query: 83 WIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVAHPLRFARLRRVKTAVAVSSVVW 142 W G CK+ +FYTN+Y SI FL CISVDR+LA+ +P + LR + A V + VW Sbjct: 82 WPFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPFKSKTLRTKRNAKIVCTGVW 141 Query: 143 ATELGANSAPLFHDELFRDRYNHT-FCFEKFPMEGWVAWMNLYRVF---VGFLFPWALML 198 T +G ++ +F N + CFE FP W +++ +F VGF P L + Sbjct: 142 LTVIGGSAPAVFVQSTHSQGNNASEACFENFPEATWKTYLSRIVIFIEIVGFFIPLILNV 201 Query: 199 LSYRGILRAVRGSVSTERQE--KAKIKRLALSLIAIVLVCFAPYHVLLLSRSAIYLGRPW 256 +L+ + V+ R + K K+ ++ + I CF PY++ L+ S + Sbjct: 202 TCSSMVLKTLTKPVTLSRSKINKTKVLKMIFVHLIIFCFCFVPYNINLILYSLVRTQTFV 261 Query: 257 DCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDV 297 +C V + Y +L NC DPI+Y ++ ++ + Sbjct: 262 NCSVVAAVRTMYPITLCIAVSNCCFDPIVYYFTSDTIQNSI 302 >gi|241982706 G-protein coupled purinergic receptor P2Y5 [Homo sapiens] Length = 344 Score = 148 bits (373), Expect = 8e-36 Identities = 87/281 (30%), Positives = 145/281 (51%), Gaps = 7/281 (2%) Query: 23 LYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLSIADLLYICTLPLWVDYFLHHDN 82 ++ V +GL +NC+A++ ++ RNE Y++NL+++DLL++ TLP + YF N Sbjct: 23 MFSMVFVLGLISNCVAIYIFICVLKVRNETTTYMINLAMSDLLFVFTLPFRIFYFTTR-N 81 Query: 83 WIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVAHPLRFARLRRVKTAVAVSSVVW 142 W G CK+ +FYTN+Y SI FL CISVDR+LA+ +P + LR + A V + VW Sbjct: 82 WPFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPFKSKTLRTKRNAKIVCTGVW 141 Query: 143 ATELGANSAPLFHDELFRDRYNHT-FCFEKFPMEGWVAWMNLYRVF---VGFLFPWALML 198 T +G ++ +F N + CFE FP W +++ +F VGF P L + Sbjct: 142 LTVIGGSAPAVFVQSTHSQGNNASEACFENFPEATWKTYLSRIVIFIEIVGFFIPLILNV 201 Query: 199 LSYRGILRAVRGSVSTERQE--KAKIKRLALSLIAIVLVCFAPYHVLLLSRSAIYLGRPW 256 +L+ + V+ R + K K+ ++ + I CF PY++ L+ S + Sbjct: 202 TCSSMVLKTLTKPVTLSRSKINKTKVLKMIFVHLIIFCFCFVPYNINLILYSLVRTQTFV 261 Query: 257 DCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDV 297 +C V + Y +L NC DPI+Y ++ ++ + Sbjct: 262 NCSVVAAVRTMYPITLCIAVSNCCFDPIVYYFTSDTIQNSI 302 >gi|33695113 G-protein coupled purinergic receptor P2Y5 [Homo sapiens] Length = 344 Score = 148 bits (373), Expect = 8e-36 Identities = 87/281 (30%), Positives = 145/281 (51%), Gaps = 7/281 (2%) Query: 23 LYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLSIADLLYICTLPLWVDYFLHHDN 82 ++ V +GL +NC+A++ ++ RNE Y++NL+++DLL++ TLP + YF N Sbjct: 23 MFSMVFVLGLISNCVAIYIFICVLKVRNETTTYMINLAMSDLLFVFTLPFRIFYFTTR-N 81 Query: 83 WIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVAHPLRFARLRRVKTAVAVSSVVW 142 W G CK+ +FYTN+Y SI FL CISVDR+LA+ +P + LR + A V + VW Sbjct: 82 WPFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPFKSKTLRTKRNAKIVCTGVW 141 Query: 143 ATELGANSAPLFHDELFRDRYNHT-FCFEKFPMEGWVAWMNLYRVF---VGFLFPWALML 198 T +G ++ +F N + CFE FP W +++ +F VGF P L + Sbjct: 142 LTVIGGSAPAVFVQSTHSQGNNASEACFENFPEATWKTYLSRIVIFIEIVGFFIPLILNV 201 Query: 199 LSYRGILRAVRGSVSTERQE--KAKIKRLALSLIAIVLVCFAPYHVLLLSRSAIYLGRPW 256 +L+ + V+ R + K K+ ++ + I CF PY++ L+ S + Sbjct: 202 TCSSMVLKTLTKPVTLSRSKINKTKVLKMIFVHLIIFCFCFVPYNINLILYSLVRTQTFV 261 Query: 257 DCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDV 297 +C V + Y +L NC DPI+Y ++ ++ + Sbjct: 262 NCSVVAAVRTMYPITLCIAVSNCCFDPIVYYFTSDTIQNSI 302 >gi|4506241 platelet-activating factor receptor [Homo sapiens] Length = 342 Score = 148 bits (373), Expect = 8e-36 Identities = 89/309 (28%), Positives = 161/309 (52%), Gaps = 13/309 (4%) Query: 7 EGCHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYR--QVQQRNELGVYLMNLSIADL 64 + H+DS + P +Y + +G+ N LW R ++ NE+ ++++NL++AD+ Sbjct: 5 DSSHMDSEFRYTLFPIVYSIIFVLGVIANGYVLWVFARLYPCKKFNEIKIFMVNLTMADM 64 Query: 65 LYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVAHPLR 124 L++ TLPLW+ Y+ + NWI C + G +F+ N Y S+AFL I+ +R+ AV P++ Sbjct: 65 LFLITLPLWIVYYQNQGNWILPKFLCNVAGCLFFINTYCSVAFLGVITYNRFQAVTRPIK 124 Query: 125 FARLRRVKTAVAVSSVVWATELGANSAPLFHDEL-----FRDRYNHTFCFEKFPMEGWVA 179 A+ K +++S V+W +GA S L D N T CFE + +G V Sbjct: 125 TAQANTRKRGISLSLVIWVAIVGAASYFLILDSTNTVPDSAGSGNVTRCFEHYE-KGSVP 183 Query: 180 WMNLYRVFVGFLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLAL----SLIAIVLV 235 + ++ V F L++L ++ ++Q A++KR AL +++A+ ++ Sbjct: 184 VLIIHIFIVFSFFLVFLIILFCNLVIIRTLLMQPVQQQRNAEVKRRALWMVCTVLAVFII 243 Query: 236 CFAPYHVLLLSRSAIYLGRPWDCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARS 295 CF P+HV+ L + LG D F + + A+ +L S NCV DP++YC + + R Sbjct: 244 CFVPHHVVQLPWTLAELGFQ-DSKFHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRK 302 Query: 296 DVAKALHNL 304 + + +++ Sbjct: 303 HLTEKFYSM 311 >gi|4885311 lysophosphatidic acid receptor 4 [Homo sapiens] Length = 370 Score = 146 bits (369), Expect = 2e-35 Identities = 102/337 (30%), Positives = 162/337 (48%), Gaps = 22/337 (6%) Query: 1 MGNHTWEG-CHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNL 59 +GN T C VD + ++Y V +GL TN ++L+ +++ R+E +++ NL Sbjct: 22 LGNATANNTCIVDDSFKYNLNGAVYSVVFILGLITNSVSLFVFCFRMKMRSETAIFITNL 81 Query: 60 SIADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAV 119 +++DLL++CTLP + Y + +W G CK+ G F TNIY S+ FL CISVDR+LA+ Sbjct: 82 AVSDLLFVCTLPFKIFYNFNR-HWPFGDTLCKISGTAFLTNIYGSMLFLTCISVDRFLAI 140 Query: 120 AHPLRFARLRRVKTAVAVSSVVWATEL-GANSAPLFHDELFRDRYNHTFCFEKFPMEGWV 178 +P R +R + + V + VW L G SA LF + T CFE F W Sbjct: 141 VYPFRSRTIRTRRNSAIVCAGVWILVLSGGISASLFSTTNVNNA--TTTCFEGFSKRVWK 198 Query: 179 AWMNLYRVF---VGFLFPWALMLLSYRGILRAVR--GSVSTERQEKAKIKRLALSLIAIV 233 +++ +F VGF+ P L + +LR +R ++S K K+ ++ +A+ Sbjct: 199 TYLSKITIFIEVVGFIIPLILNVSCSSVVLRTLRKPATLSQIGTNKKKVLKMITVHMAVF 258 Query: 234 LVCFAPYHVLLLSRSAIYLGRPWDCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGA 293 +VCF PY+ +L + + +C E Y +L +LNC DP +Y E Sbjct: 259 VVCFVPYNSVLFLYALVRSQAITNCFLERFAKIMYPITLCLATLNCCFDPFIYYFTLESF 318 Query: 294 RSDVAKALHNLLRFLASDKPQEMANASLTLETPLTSK 330 + H + L ETPLT+K Sbjct: 319 QKSFYINAHIRMESL------------FKTETPLTTK 343 >gi|34577052 coagulation factor II (thrombin) receptor-like 1 precursor [Homo sapiens] Length = 397 Score = 145 bits (367), Expect = 4e-35 Identities = 98/335 (29%), Positives = 171/335 (51%), Gaps = 25/335 (7%) Query: 18 LFPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLSIADLLYICTLPLWVDYF 77 +F P +Y V VGLP+N +ALW + ++++ +Y+ NL++ADLL + PL + Y Sbjct: 76 VFLPIVYTIVFVVGLPSNGMALWVFLFRTKKKHPAVIYMANLALADLLSVIWFPLKIAYH 135 Query: 78 LHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVAHPLRFARLRRVKTAVAV 137 +H +NWI+G C + FY N+Y SI F+ C+SV RY + +P+ +R ++ A+ + Sbjct: 136 IHGNNWIYGEALCNVLIGFFYGNMYCSILFMTCLSVQRYWVIVNPMGHSR-KKANIAIGI 194 Query: 138 SSVVWATELGANSAPLF--HDELFRDRYNHTFCFEKFPMEGWVAWMNLYRVFVG---FLF 192 S +W L + PL+ +F N T C + P + V M Y + + FLF Sbjct: 195 SLAIWLLIL-LVTIPLYVVKQTIFIPALNITTCHDVLPEQLLVGDMFNYFLSLAIGVFLF 253 Query: 193 PWALMLLSYRGILRAVRGSVSTERQEKAKIK--RLALSLIAIVLVCFAPYHVLLLSRSAI 250 P L +Y ++R +R S E EK + + +L ++++A+ L+CF P ++LL+ + Sbjct: 254 PAFLTASAYVLMIRMLRSSAMDENSEKKRKRAIKLIVTVLAMYLICFTPSNLLLVVHYFL 313 Query: 251 YLGRPWDCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDVAKALHNLLRFLAS 310 + + V++ Y +L ++LN DP +Y V+ R AL L R + + Sbjct: 314 IKSQG-----QSHVYALYIVALCLSTLNSCIDPFVYYFVSHDFRDHAKNAL--LCRSVRT 366 Query: 311 DKPQEMANASLTLETPLTSKRNSTAKAMTGSWAAT 345 K +++ LTSK++S + S + T Sbjct: 367 VKQMQVS---------LTSKKHSRKSSSYSSSSTT 392 >gi|238814307 G protein-coupled receptor 17 isoform b [Homo sapiens] Length = 339 Score = 145 bits (367), Expect = 4e-35 Identities = 98/302 (32%), Positives = 149/302 (49%), Gaps = 9/302 (2%) Query: 5 TWEGCHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLSIADL 64 T E C ++ ++++ S Y+ + L N LALW R + V+LM+L++ADL Sbjct: 19 TAEQCGQETPLENMLFASFYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADL 78 Query: 65 LYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVAHPLR 124 + LP + Y ++W G +C+L GF+FY N+Y SI FL CIS DR+LA+ HP++ Sbjct: 79 SCVLVLPTRLVYHFSGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVK 138 Query: 125 FARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHT-FCFEKFPMEGWVAWMNL 183 +LRR A + +W A + L + + NHT C + + + + L Sbjct: 139 SLKLRRPLYAHLACAFLWVVVAVAMAPLLVSPQTVQT--NHTVVCLQLYREK--ASHHAL 194 Query: 184 YRVFVGFLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVLVCFAPYHVL 243 + V F FP+ + Y I+R++R + E++ K K R+ ++AI LVCF PYHV Sbjct: 195 VSLAVAFTFPFITTVTCYLLIIRSLRQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVN 254 Query: 244 LLSRSAIYLGRPWDCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDVAKALHN 303 Y C + + A + TSLN DPI+Y V E R AL N Sbjct: 255 RSVYVLHYRSHGASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFR----HALCN 310 Query: 304 LL 305 LL Sbjct: 311 LL 312 >gi|238814305 G protein-coupled receptor 17 isoform b [Homo sapiens] Length = 339 Score = 145 bits (367), Expect = 4e-35 Identities = 98/302 (32%), Positives = 149/302 (49%), Gaps = 9/302 (2%) Query: 5 TWEGCHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLSIADL 64 T E C ++ ++++ S Y+ + L N LALW R + V+LM+L++ADL Sbjct: 19 TAEQCGQETPLENMLFASFYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADL 78 Query: 65 LYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVAHPLR 124 + LP + Y ++W G +C+L GF+FY N+Y SI FL CIS DR+LA+ HP++ Sbjct: 79 SCVLVLPTRLVYHFSGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVK 138 Query: 125 FARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHT-FCFEKFPMEGWVAWMNL 183 +LRR A + +W A + L + + NHT C + + + + L Sbjct: 139 SLKLRRPLYAHLACAFLWVVVAVAMAPLLVSPQTVQT--NHTVVCLQLYREK--ASHHAL 194 Query: 184 YRVFVGFLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVLVCFAPYHVL 243 + V F FP+ + Y I+R++R + E++ K K R+ ++AI LVCF PYHV Sbjct: 195 VSLAVAFTFPFITTVTCYLLIIRSLRQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVN 254 Query: 244 LLSRSAIYLGRPWDCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDVAKALHN 303 Y C + + A + TSLN DPI+Y V E R AL N Sbjct: 255 RSVYVLHYRSHGASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFR----HALCN 310 Query: 304 LL 305 LL Sbjct: 311 LL 312 >gi|4885301 G protein-coupled receptor 17 isoform a [Homo sapiens] Length = 367 Score = 145 bits (367), Expect = 4e-35 Identities = 98/302 (32%), Positives = 149/302 (49%), Gaps = 9/302 (2%) Query: 5 TWEGCHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLSIADL 64 T E C ++ ++++ S Y+ + L N LALW R + V+LM+L++ADL Sbjct: 47 TAEQCGQETPLENMLFASFYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADL 106 Query: 65 LYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVAHPLR 124 + LP + Y ++W G +C+L GF+FY N+Y SI FL CIS DR+LA+ HP++ Sbjct: 107 SCVLVLPTRLVYHFSGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVK 166 Query: 125 FARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHT-FCFEKFPMEGWVAWMNL 183 +LRR A + +W A + L + + NHT C + + + + L Sbjct: 167 SLKLRRPLYAHLACAFLWVVVAVAMAPLLVSPQTVQT--NHTVVCLQLYREK--ASHHAL 222 Query: 184 YRVFVGFLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVLVCFAPYHVL 243 + V F FP+ + Y I+R++R + E++ K K R+ ++AI LVCF PYHV Sbjct: 223 VSLAVAFTFPFITTVTCYLLIIRSLRQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVN 282 Query: 244 LLSRSAIYLGRPWDCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDVAKALHN 303 Y C + + A + TSLN DPI+Y V E R AL N Sbjct: 283 RSVYVLHYRSHGASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFR----HALCN 338 Query: 304 LL 305 LL Sbjct: 339 LL 340 >gi|238814302 G protein-coupled receptor 17 isoform a [Homo sapiens] Length = 367 Score = 145 bits (367), Expect = 4e-35 Identities = 98/302 (32%), Positives = 149/302 (49%), Gaps = 9/302 (2%) Query: 5 TWEGCHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLSIADL 64 T E C ++ ++++ S Y+ + L N LALW R + V+LM+L++ADL Sbjct: 47 TAEQCGQETPLENMLFASFYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADL 106 Query: 65 LYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVAHPLR 124 + LP + Y ++W G +C+L GF+FY N+Y SI FL CIS DR+LA+ HP++ Sbjct: 107 SCVLVLPTRLVYHFSGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVK 166 Query: 125 FARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHT-FCFEKFPMEGWVAWMNL 183 +LRR A + +W A + L + + NHT C + + + + L Sbjct: 167 SLKLRRPLYAHLACAFLWVVVAVAMAPLLVSPQTVQT--NHTVVCLQLYREK--ASHHAL 222 Query: 184 YRVFVGFLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVLVCFAPYHVL 243 + V F FP+ + Y I+R++R + E++ K K R+ ++AI LVCF PYHV Sbjct: 223 VSLAVAFTFPFITTVTCYLLIIRSLRQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVN 282 Query: 244 LLSRSAIYLGRPWDCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDVAKALHN 303 Y C + + A + TSLN DPI+Y V E R AL N Sbjct: 283 RSVYVLHYRSHGASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFR----HALCN 338 Query: 304 LL 305 LL Sbjct: 339 LL 340 >gi|4505557 purinergic receptor P2Y1 [Homo sapiens] Length = 373 Score = 143 bits (361), Expect = 2e-34 Identities = 91/294 (30%), Positives = 149/294 (50%), Gaps = 12/294 (4%) Query: 21 PSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLSIADLLYICTLPLWVDYFLHH 80 P++YI V +G N +A+W ++ + + VY+ NL++AD LY+ TLP + Y+ + Sbjct: 55 PAVYILVFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNK 114 Query: 81 DNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVAHPLRFARLRRVKTAVAVSSV 140 +WI G CKL FIF+ N+Y SI FL CIS RY V +PL+ + K A+ +S + Sbjct: 115 TDWIFGDAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISVL 174 Query: 141 VWATELGANSAPLFHDELFRDRYNHTFCFEKFPMEGWVAWM--NLYRVFVGFLFPWALML 198 VW + A S LF+ + C++ E ++ ++ F P L+L Sbjct: 175 VWLIVVVAISPILFYSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLIL 234 Query: 199 LSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVLVCFA----PYHVL--LLSRSAIYL 252 Y I+RA + + + + ++R ++ L+ IVL FA P+HV+ + R+ + Sbjct: 235 GCYGLIVRA----LIYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDF 290 Query: 253 GRPWDCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDVAKALHNLLR 306 P C F +RV++ Y + SLN DPILY L + R +++A R Sbjct: 291 QTPAMCAFNDRVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASR 344 >gi|4502631 chemokine (C-C motif) receptor 1 [Homo sapiens] Length = 355 Score = 137 bits (346), Expect = 1e-32 Identities = 85/311 (27%), Positives = 150/311 (48%), Gaps = 16/311 (5%) Query: 21 PSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLSIADLLYICTLPLWVDYFLHH 80 P LY V +GL N L + + + +N +YL+NL+I+DLL++ TLP W+DY L Sbjct: 38 PPLYSLVFVIGLVGNILVVLVLVQYKRLKNMTSIYLLNLAISDLLFLFTLPFWIDYKLK- 96 Query: 81 DNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVAHPLRFARLRRVKTAVAVSSV 140 D+W+ G CK+ +YT +Y I F+ +++DRYLA+ H + R R V V S + Sbjct: 97 DDWVFGDAMCKILSGFYYTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSII 156 Query: 141 VWATELGANSAPLFHDELFRDRYNHTFCFEKFPMEG---WVAWMNLYRVFVGFLFPWALM 197 +WA + A+ L+ + + +HT C FP E W + L G + P +M Sbjct: 157 IWALAILASMPGLYFSKTQWEFTHHT-CSLHFPHESLREWKLFQALKLNLFGLVLPLLVM 215 Query: 198 LLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVLVCFAPYHVLLLSRSAIYLGRPWD 257 ++ Y GI++ + + ++K+K RL ++ I + + PY++ +L + Sbjct: 216 IICYTGIIKIL---LRRPNEKKSKAVRLIFVIMIIFFLFWTPYNLTILISVFQDFLFTHE 272 Query: 258 CGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDVAKALH--------NLLRFLA 309 C + A + +C +P++Y V E R + + H L FL+ Sbjct: 273 CEQSRHLDLAVQVTEVIAYTHCCVNPVIYAFVGERFRKYLRQLFHRRVAVHLVKWLPFLS 332 Query: 310 SDKPQEMANAS 320 D+ + +++ S Sbjct: 333 VDRLERVSSTS 343 >gi|5031627 chemokine (C-C motif) receptor 4 [Homo sapiens] Length = 360 Score = 135 bits (340), Expect = 6e-32 Identities = 78/279 (27%), Positives = 139/279 (49%), Gaps = 8/279 (2%) Query: 18 LFPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLSIADLLYICTLPLWVDYF 77 LF P LY V GL N + + ++ + R+ VYL+NL+I+DLL++ +LP W Y Sbjct: 40 LFLPPLYSLVFVFGLLGNSVVVLVLFKYKRLRSMTDVYLLNLAISDLLFVFSLPFWGYYA 99 Query: 78 LHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVAHPLRFARLRRVKTAVAV 137 D W+ G G CK+ +++ Y I F+ +S+DRYLA+ H + R R + V Sbjct: 100 A--DQWVFGLGLCKMISWMYLVGFYSGIFFVMLMSIDRYLAIVHAVFSLRARTLTYGVIT 157 Query: 138 SSVVWATELGANSAPLFHDELFRDRYNHTFCFEKFPMEG--WVAWMNLYRVFVGFLFPWA 195 S W+ + A+ + +R NHT+C K+ + W +L +G + P Sbjct: 158 SLATWSVAVFASLPGFLFSTCYTER-NHTYCKTKYSLNSTTWKVLSSLEINILGLVIPLG 216 Query: 196 LMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVLVCFAPYHVLLLSRSAIYLGRP 255 +ML Y I+R ++ + ++K K ++ +++ + L + PY+++L + + L Sbjct: 217 IMLFCYSMIIRTLQ---HCKNEKKNKAVKMIFAVVVLFLGFWTPYNIVLFLETLVELEVL 273 Query: 256 WDCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGAR 294 DC FE + A ++ ++C +PI+Y + E R Sbjct: 274 QDCTFERYLDYAIQATETLAFVHCCLNPIIYFFLGEKFR 312 >gi|52426789 oxoglutarate (alpha-ketoglutarate) receptor 1 [Homo sapiens] Length = 337 Score = 135 bits (339), Expect = 7e-32 Identities = 79/283 (27%), Positives = 132/283 (46%), Gaps = 4/283 (1%) Query: 21 PSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLSIADLLYICTLPLWVDYFLHH 80 P +Y + VG P N + + +++ + ++NL+ DLLY+ +LP + Y+ Sbjct: 37 PVIYGIIFLVGFPGNAVVISTYIFKMRPWKSSTIIMLNLACTDLLYLTSLPFLIHYYASG 96 Query: 81 DNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVAHPLRFARLRRVKTAVAVSSV 140 +NWI G CK F F+ N+Y SI FL C S+ RY + HP+ + + + AV +V Sbjct: 97 ENWIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVIIHPMSCFSIHKTRCAVVACAV 156 Query: 141 VWATELGANSAPLFHDELFRDRYNHTFCFEKFPME--GWVAWMNLYRVFVGFLFPWALML 198 VW L A P+ +R N + C + + + W NL F P ++ Sbjct: 157 VWIISLVA-VIPMTFLITSTNRTNRSACLDLTSSDELNTIKWYNLILTATTFCLPLVIVT 215 Query: 199 LSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVLVCFAPYHVLLLSRSAIYLGRPWDC 258 L Y I+ + + T+ K K +RL + L+ VCF P+H+L + R L C Sbjct: 216 LCYTTIIHTLTHGLQTDSCLKQKARRLTILLLLAFYVCFLPFHILRVIRIESRL-LSISC 274 Query: 259 GFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDVAKAL 301 E ++ AY S +LN + +LY +V++ + V + Sbjct: 275 SIENQIHEAYIVSRPLAALNTFGNLLLYVVVSDNFQQAVCSTV 317 >gi|28872720 purinergic receptor P2Y2 [Homo sapiens] Length = 377 Score = 134 bits (338), Expect = 1e-31 Identities = 101/325 (31%), Positives = 149/325 (45%), Gaps = 29/325 (8%) Query: 3 NHTWEG------CHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYL 56 N TW+G C + ++ P Y V GL N +AL+ +++ N Y+ Sbjct: 13 NGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYM 72 Query: 57 MNLSIADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRY 116 +L+++D LY +LPL V Y+ D+W CKL F+FYTN+Y SI FL CISV R Sbjct: 73 FHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRC 132 Query: 117 LAVAHPLRFARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHTFCFEKFPMEG 176 L V PLR R R + A V+ VW L A AP+ + R C + E Sbjct: 133 LGVLRPLRSLRWGRARYARRVAGAVWVLVL-ACQAPVLYFVTTSARGGRVTCHDTSAPEL 191 Query: 177 WVAWMNLYRVFVGFLF--PWALMLLSY----RGILRAVRGSVSTERQEKAKIKRLALSLI 230 + ++ V +G LF P+A++L+ Y R +L+ G+ + K K R ++ Sbjct: 192 FSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAKRKSVRTIAVVL 251 Query: 231 AIVLVCFAPYHVLLLSRSAIYLGRPWD--CGFEERVFSAYHSSLAFTSLNCVADPILYCL 288 A+ +CF P+HV +R+ Y R D C + AY + S N DP+LY L Sbjct: 252 AVFALCFLPFHV---TRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSCLDPVLYFL 308 Query: 289 VNEGARSDVAKALHNLLRFLASDKP 313 + L+RF KP Sbjct: 309 AGQ-----------RLVRFARDAKP 322 >gi|28872745 purinergic receptor P2Y2 [Homo sapiens] Length = 377 Score = 134 bits (338), Expect = 1e-31 Identities = 101/325 (31%), Positives = 149/325 (45%), Gaps = 29/325 (8%) Query: 3 NHTWEG------CHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYL 56 N TW+G C + ++ P Y V GL N +AL+ +++ N Y+ Sbjct: 13 NGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYM 72 Query: 57 MNLSIADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRY 116 +L+++D LY +LPL V Y+ D+W CKL F+FYTN+Y SI FL CISV R Sbjct: 73 FHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRC 132 Query: 117 LAVAHPLRFARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHTFCFEKFPMEG 176 L V PLR R R + A V+ VW L A AP+ + R C + E Sbjct: 133 LGVLRPLRSLRWGRARYARRVAGAVWVLVL-ACQAPVLYFVTTSARGGRVTCHDTSAPEL 191 Query: 177 WVAWMNLYRVFVGFLF--PWALMLLSY----RGILRAVRGSVSTERQEKAKIKRLALSLI 230 + ++ V +G LF P+A++L+ Y R +L+ G+ + K K R ++ Sbjct: 192 FSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAKRKSVRTIAVVL 251 Query: 231 AIVLVCFAPYHVLLLSRSAIYLGRPWD--CGFEERVFSAYHSSLAFTSLNCVADPILYCL 288 A+ +CF P+HV +R+ Y R D C + AY + S N DP+LY L Sbjct: 252 AVFALCFLPFHV---TRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSCLDPVLYFL 308 Query: 289 VNEGARSDVAKALHNLLRFLASDKP 313 + L+RF KP Sbjct: 309 AGQ-----------RLVRFARDAKP 322 >gi|28872743 purinergic receptor P2Y2 [Homo sapiens] Length = 377 Score = 134 bits (338), Expect = 1e-31 Identities = 101/325 (31%), Positives = 149/325 (45%), Gaps = 29/325 (8%) Query: 3 NHTWEG------CHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYL 56 N TW+G C + ++ P Y V GL N +AL+ +++ N Y+ Sbjct: 13 NGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYM 72 Query: 57 MNLSIADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRY 116 +L+++D LY +LPL V Y+ D+W CKL F+FYTN+Y SI FL CISV R Sbjct: 73 FHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRC 132 Query: 117 LAVAHPLRFARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHTFCFEKFPMEG 176 L V PLR R R + A V+ VW L A AP+ + R C + E Sbjct: 133 LGVLRPLRSLRWGRARYARRVAGAVWVLVL-ACQAPVLYFVTTSARGGRVTCHDTSAPEL 191 Query: 177 WVAWMNLYRVFVGFLF--PWALMLLSY----RGILRAVRGSVSTERQEKAKIKRLALSLI 230 + ++ V +G LF P+A++L+ Y R +L+ G+ + K K R ++ Sbjct: 192 FSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAKRKSVRTIAVVL 251 Query: 231 AIVLVCFAPYHVLLLSRSAIYLGRPWD--CGFEERVFSAYHSSLAFTSLNCVADPILYCL 288 A+ +CF P+HV +R+ Y R D C + AY + S N DP+LY L Sbjct: 252 AVFALCFLPFHV---TRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSCLDPVLYFL 308 Query: 289 VNEGARSDVAKALHNLLRFLASDKP 313 + L+RF KP Sbjct: 309 AGQ-----------RLVRFARDAKP 322 >gi|4826706 EBV-induced G protein-coupled receptor 2 [Homo sapiens] Length = 361 Score = 134 bits (338), Expect = 1e-31 Identities = 79/290 (27%), Positives = 139/290 (47%), Gaps = 10/290 (3%) Query: 21 PSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLSIADLLYICTLPLWVDYFLHH 80 P Y V +GL N LAL + ++ N +Y NL I+D+L+ LP + Y+ Sbjct: 35 PLHYSLVFIIGLVGNLLALVVIVQNRKKINSTTLYSTNLVISDILFTTALPTRIAYYAMG 94 Query: 81 DNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVAHPLRFARLRRVKTAVAVSSV 140 +W G C++ +FY N Y + F+ C+S+DR++AV HPLR+ +++R++ A V Sbjct: 95 FDWRIGDALCRITALVFYINTYAGVNFMTCLSIDRFIAVVHPLRYNKIKRIEHAKGVCIF 154 Query: 141 VWATELGANSAPLFHDELFRDRYNHTFCFE--KFPMEGWVAWMNLYRVFVGFLFPWALML 198 VW + A + PL + + + C E F + W+ L F+G++ P ++L Sbjct: 155 VWIL-VFAQTLPLLINPMSKQEAERITCMEYPNFEETKSLPWILLGACFIGYVLPLIIIL 213 Query: 199 LSYRGI-LRAVRGSVSTERQEKAKIKRLALSLIAIVLV----CFAPYHVLLLSR--SAIY 251 + Y I + R + EK+ + + AL+ I +++V CF PYHV ++ + Sbjct: 214 ICYSQICCKLFRTAKQNPLTEKSGVNKKALNTIILIIVVFVLCFTPYHVAIIQHMIKKLR 273 Query: 252 LGRPWDCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDVAKAL 301 +C + H ++ + NC DP +Y +G + V + L Sbjct: 274 FSNFLECSQRHSFQISLHFTVCLMNFNCCMDPFIYFFACKGYKRKVMRML 323 >gi|219281887 lysophosphatidic acid receptor 5 [Homo sapiens] Length = 372 Score = 134 bits (336), Expect = 2e-31 Identities = 98/295 (33%), Positives = 138/295 (46%), Gaps = 16/295 (5%) Query: 12 DSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLSIADLLYICTLP 71 D R H +Y V+ GLP N LALW R ++ + + VY+ NL+ +DLL+ +LP Sbjct: 17 DYRPTHRLHLVVYSLVLAAGLPLNALALWVFLRALRVHSVVSVYMCNLAASDLLFTLSLP 76 Query: 72 LWVDYF-LHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVAHPLRFARLRR 130 + + Y+ LHH W C+ G IF N+Y S FL I+VDRY A+ HPLR LRR Sbjct: 77 VRLSYYALHH--WPFPDLLCQTTGAIFQMNMYGSCIFLMLINVDRYAAIVHPLRLRHLRR 134 Query: 131 VKTAVAVSSVVWATELGANSAPLFHDELFRDRYNH---TFCFEKFPMEGW---VAWMNLY 184 + A + VWA L R RY CFE F E W + + L Sbjct: 135 PRVARLLCLGVWALILVFAVPAARVHRPSRCRYRDLEVRLCFESFSDELWKGRLLPLVLL 194 Query: 185 RVFVGFLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVLVCFAPYHVLL 244 +GFL P A ++ S + + +T+ Q + K RL L+ + I L+CF PY+ L Sbjct: 195 AEALGFLLPLAAVVYSSGRVFWTLARPDATQSQRRRKTVRLLLANLVIFLLCFVPYNSTL 254 Query: 245 ----LSRSAIYLGRPWDCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARS 295 L RS + +RV + NCV DP++Y EG R+ Sbjct: 255 AVYGLLRSKLVAA---SVPARDRVRGVLMVMVLLAGANCVLDPLVYYFSAEGFRN 306 >gi|9966879 lysophosphatidic acid receptor 5 [Homo sapiens] Length = 372 Score = 134 bits (336), Expect = 2e-31 Identities = 98/295 (33%), Positives = 138/295 (46%), Gaps = 16/295 (5%) Query: 12 DSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLSIADLLYICTLP 71 D R H +Y V+ GLP N LALW R ++ + + VY+ NL+ +DLL+ +LP Sbjct: 17 DYRPTHRLHLVVYSLVLAAGLPLNALALWVFLRALRVHSVVSVYMCNLAASDLLFTLSLP 76 Query: 72 LWVDYF-LHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVAHPLRFARLRR 130 + + Y+ LHH W C+ G IF N+Y S FL I+VDRY A+ HPLR LRR Sbjct: 77 VRLSYYALHH--WPFPDLLCQTTGAIFQMNMYGSCIFLMLINVDRYAAIVHPLRLRHLRR 134 Query: 131 VKTAVAVSSVVWATELGANSAPLFHDELFRDRYNH---TFCFEKFPMEGW---VAWMNLY 184 + A + VWA L R RY CFE F E W + + L Sbjct: 135 PRVARLLCLGVWALILVFAVPAARVHRPSRCRYRDLEVRLCFESFSDELWKGRLLPLVLL 194 Query: 185 RVFVGFLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVLVCFAPYHVLL 244 +GFL P A ++ S + + +T+ Q + K RL L+ + I L+CF PY+ L Sbjct: 195 AEALGFLLPLAAVVYSSGRVFWTLARPDATQSQRRRKTVRLLLANLVIFLLCFVPYNSTL 254 Query: 245 ----LSRSAIYLGRPWDCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARS 295 L RS + +RV + NCV DP++Y EG R+ Sbjct: 255 AVYGLLRSKLVAA---SVPARDRVRGVLMVMVLLAGANCVLDPLVYYFSAEGFRN 306 >gi|30581170 CC chemokine receptor 3 [Homo sapiens] Length = 355 Score = 130 bits (326), Expect = 2e-30 Identities = 88/321 (27%), Positives = 149/321 (46%), Gaps = 20/321 (6%) Query: 19 FPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLSIADLLYICTLPLWVDYFL 78 F P LY V VGL N + + + + R +YL+NL+I+DLL++ TLP W+ Y Sbjct: 36 FVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVR 95 Query: 79 HHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVAHPLRFARLRRVKTAVAVS 138 H NW+ G G CKL ++T +Y I F+ +++DRYLA+ H + R R V V S Sbjct: 96 GH-NWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITS 154 Query: 139 SVVWATELGANSAPLFHDELFRDRYNHTFCFEKFPMEGWVAWMNLYRV---FVGFLFPWA 195 V W + A + P F + + T C +P + +W + + + + P Sbjct: 155 IVTWGLAVLA-ALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLL 213 Query: 196 LMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVLVCFAPYHV--LLLSRSAIYLG 253 +M + Y GI++ + + ++K K RL ++A+ + + PY+V LL S +I G Sbjct: 214 VMAICYTGIIKTL---LRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFG 270 Query: 254 RPWDCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDVAKALH--------NLL 305 DC + + + +C +P++Y V E R + H + Sbjct: 271 N--DCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYI 328 Query: 306 RFLASDKPQEMANASLTLETP 326 FL S+K + ++ S + P Sbjct: 329 PFLPSEKLERTSSVSPSTAEP 349 >gi|4502637 CC chemokine receptor 3 [Homo sapiens] Length = 355 Score = 130 bits (326), Expect = 2e-30 Identities = 88/321 (27%), Positives = 149/321 (46%), Gaps = 20/321 (6%) Query: 19 FPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLSIADLLYICTLPLWVDYFL 78 F P LY V VGL N + + + + R +YL+NL+I+DLL++ TLP W+ Y Sbjct: 36 FVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVR 95 Query: 79 HHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVAHPLRFARLRRVKTAVAVS 138 H NW+ G G CKL ++T +Y I F+ +++DRYLA+ H + R R V V S Sbjct: 96 GH-NWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITS 154 Query: 139 SVVWATELGANSAPLFHDELFRDRYNHTFCFEKFPMEGWVAWMNLYRV---FVGFLFPWA 195 V W + A + P F + + T C +P + +W + + + + P Sbjct: 155 IVTWGLAVLA-ALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLL 213 Query: 196 LMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVLVCFAPYHV--LLLSRSAIYLG 253 +M + Y GI++ + + ++K K RL ++A+ + + PY+V LL S +I G Sbjct: 214 VMAICYTGIIKTL---LRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFG 270 Query: 254 RPWDCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDVAKALH--------NLL 305 DC + + + +C +P++Y V E R + H + Sbjct: 271 N--DCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYI 328 Query: 306 RFLASDKPQEMANASLTLETP 326 FL S+K + ++ S + P Sbjct: 329 PFLPSEKLERTSSVSPSTAEP 349 >gi|4505561 pyrimidinergic receptor P2Y4 [Homo sapiens] Length = 365 Score = 130 bits (326), Expect = 2e-30 Identities = 100/347 (28%), Positives = 156/347 (44%), Gaps = 30/347 (8%) Query: 9 CHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLSIADLLYIC 68 C D + P Y V +GL N LW +++ + Y+ +L+++D LY+ Sbjct: 27 CWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVL 86 Query: 69 TLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVAHPLRFARL 128 +LP + Y+ H++W G CK F+FY N+Y S+ FL CISV RYL + HPLR R Sbjct: 87 SLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRW 146 Query: 129 RRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHTFCFEKFPMEGWVAWMNLYRVFV 188 R + A + VW G LF ++ C + E + +++ + Sbjct: 147 GRPRLAGLLCLAVWLVVAGCLVPNLFF-VTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVM 205 Query: 189 GFLF--PWALMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVL----VCFAPYHV 242 G LF P + L+ Y + R + + Q ++++ +L IA+VL VCF P+H+ Sbjct: 206 GLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLR--SLRTIAVVLTVFAVCFVPFHI 263 Query: 243 LLLSRSAIYLGR--PWDCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDVAKA 300 +R+ YL R DC V Y + S N DP+LY L + K Sbjct: 264 ---TRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGD-------KY 313 Query: 301 LHNLLRFLASDKPQ-EMANASLTLETPLTSKRNSTAKAMTGSWAATP 346 L + KPQ A +SL L ++ +S+ + WAATP Sbjct: 314 RRQLRQLCGGGKPQPRTAASSLAL---VSLPEDSSCR-----WAATP 352 >gi|4758326 coagulation factor II (thrombin) receptor-like 2 precursor [Homo sapiens] Length = 374 Score = 127 bits (318), Expect = 2e-29 Identities = 83/283 (29%), Positives = 135/283 (47%), Gaps = 29/283 (10%) Query: 21 PSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLSIADLLYICTLPLWVDYFLHH 80 P++Y+ V VG+P N + LW + + + V+ NL+IAD L+ TLP + Y L+ Sbjct: 98 PAIYLLVFVVGVPANAVTLWMLFFRTRSICTT-VFYTNLAIADFLFCVTLPFKIAYHLNG 156 Query: 81 DNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVAHPLRFARLRRVKTAVAVSSV 140 +NW+ G C+ IFY N+Y SI L CIS++RYLA+ HP + L + A+ + Sbjct: 157 NNWVFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPFTYRGLPKHTYALVTCGL 216 Query: 141 VWATELGANSAPLFHDELFRDRYN------------HTFCFEKFPMEGWVAWMNLYRVFV 188 VWAT + P F + + Y H C P + + + F Sbjct: 217 VWAT-VFLYMLPFF---ILKQEYYLVQPDITTCHDVHNTCESSSPFQ---LYYFISLAFF 269 Query: 189 GFLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVLVCFAPYHVLLLSRS 248 GFL P+ L++ Y I+R +++ + +L ++ I +CFAP +++L+ Sbjct: 270 GFLIPFVLIIYCYAAIIR----TLNAYDHRWLWYVKASLLILVIFTICFAPSNIILIIHH 325 Query: 249 AIYLGRPWDCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNE 291 A Y D ++ Y +L SLN DP LY L+++ Sbjct: 326 ANYYYNNTD-----GLYFIYLIALCLGSLNSCLDPFLYFLMSK 363 >gi|4885057 apelin receptor [Homo sapiens] Length = 380 Score = 125 bits (313), Expect = 8e-29 Identities = 85/283 (30%), Positives = 139/283 (49%), Gaps = 22/283 (7%) Query: 21 PSLYIFVIGVGLPTNCLALWAAYRQVQQ-RNELGVYLMNLSIADLLYICTLPLWVDYFLH 79 P++Y+ V +G N L LW +R ++ R +++ +L++ADL ++ TLPLW Y Sbjct: 32 PAIYMLVFLLGTTGNGLVLWTVFRSSREKRRSADIFIASLAVADLTFVVTLPLWATYTYR 91 Query: 80 HDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVAHPLRFARLR-RVKTAVAVS 138 +W G CKL ++ + N+Y S+ L +S DRYLA+ P+ ARLR RV AVA + Sbjct: 92 DYDWPFGTFFCKLSSYLIFVNMYASVFCLTGLSFDRYLAIVRPVANARLRLRVSGAVA-T 150 Query: 139 SVVWATELGANSAPLFHDELFRDRYNHT--FCFEKFPME-------GWVAWMNLYRVFVG 189 +V+W + P+ D N T C+ + M W + + VG Sbjct: 151 AVLWVL-AALLAMPVMVLRTTGDLENTTKVQCYMDYSMVATVSSEWAWEVGLGVSSTTVG 209 Query: 190 FLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVLV----CFAPYHVLLL 245 F+ P+ +ML Y I + + G ER E + +R LS+I +++V C+ PYH L Sbjct: 210 FVVPFTIMLTCYFFIAQTIAGHFRKERIEGLRKRRRLLSIIVVLVVTFALCWMPYH---L 266 Query: 246 SRSAIYLGR--PWDCGFEERVFSAYHSSLAFTSLNCVADPILY 286 ++ LG W C F+ + + + + +N +P LY Sbjct: 267 VKTLYMLGSLLHWPCDFDLFLMNIFPYCTCISYVNSCLNPFLY 309 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.327 0.139 0.452 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,535,346 Number of Sequences: 37866 Number of extensions: 538035 Number of successful extensions: 2763 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 384 Number of HSP's successfully gapped in prelim test: 281 Number of HSP's that attempted gapping in prelim test: 1779 Number of HSP's gapped (non-prelim): 740 length of query: 362 length of database: 18,247,518 effective HSP length: 104 effective length of query: 258 effective length of database: 14,309,454 effective search space: 3691839132 effective search space used: 3691839132 T: 11 A: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.7 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.