Guide to the Human Genome
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Search of human proteins with 4885307

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4885307 G protein-coupled receptor 21 [Homo sapiens]
         (349 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4885307 G protein-coupled receptor 21 [Homo sapiens]               721   0.0  
gi|187960055 G protein-coupled receptor 52 [Homo sapiens]             481   e-136
gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens]            98   1e-20
gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens]             98   1e-20
gi|24476016 G protein-coupled receptor 161 isoform 2 [Homo sapiens]    95   8e-20
gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens]       94   2e-19
gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]                 91   2e-18
gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]          89   4e-18
gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]          89   4e-18
gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens]          89   4e-18
gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens]          89   4e-18
gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens]          89   4e-18
gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens]          89   4e-18
gi|222080109 orexin receptor 2 [Homo sapiens]                          89   6e-18
gi|4557265 beta-1-adrenergic receptor [Homo sapiens]                   89   6e-18
gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens]         86   6e-17
gi|4501953 adenosine A3 receptor isoform 2 [Homo sapiens]              85   8e-17
gi|110618256 trace amine associated receptor 9 [Homo sapiens]          85   1e-16
gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens]                84   2e-16
gi|28173558 trace amine associated receptor 6 [Homo sapiens]           83   3e-16
gi|167000885 galanin receptor 1 [Homo sapiens]                         82   9e-16
gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens]     81   1e-15
gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens]     81   1e-15
gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens]     81   1e-15
gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens]     81   1e-15
gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo sapi...    81   1e-15
gi|16751917 trace amine associated receptor 8 [Homo sapiens]           79   5e-15
gi|16604258 neuropeptide FF receptor 2 isoform 2 [Homo sapiens]        78   1e-14
gi|221316654 neuropeptide FF receptor 2 isoform 1 [Homo sapiens]       78   1e-14
gi|221316652 neuropeptide FF receptor 2 isoform 3 [Homo sapiens]       78   1e-14

>gi|4885307 G protein-coupled receptor 21 [Homo sapiens]
          Length = 349

 Score =  721 bits (1862), Expect = 0.0
 Identities = 349/349 (100%), Positives = 349/349 (100%)

Query: 1   MNSTLDGNQSSHPFCLLAFGYLETVNFCLLEVLIIVFLTVLIISGNIIVIFVFHCAPLLN 60
           MNSTLDGNQSSHPFCLLAFGYLETVNFCLLEVLIIVFLTVLIISGNIIVIFVFHCAPLLN
Sbjct: 1   MNSTLDGNQSSHPFCLLAFGYLETVNFCLLEVLIIVFLTVLIISGNIIVIFVFHCAPLLN 60

Query: 61  HHTTSYFIQTMAYADLFVGVSCVVPSLSLLHHPLPVEESLTCQIFGFVVSVLKSVSMASL 120
           HHTTSYFIQTMAYADLFVGVSCVVPSLSLLHHPLPVEESLTCQIFGFVVSVLKSVSMASL
Sbjct: 61  HHTTSYFIQTMAYADLFVGVSCVVPSLSLLHHPLPVEESLTCQIFGFVVSVLKSVSMASL 120

Query: 121 ACISIDRYIAITKPLTYNTLVTPWRLRLCIFLIWLYSTLVFLPSFFHWGKPGYHGDVFQW 180
           ACISIDRYIAITKPLTYNTLVTPWRLRLCIFLIWLYSTLVFLPSFFHWGKPGYHGDVFQW
Sbjct: 121 ACISIDRYIAITKPLTYNTLVTPWRLRLCIFLIWLYSTLVFLPSFFHWGKPGYHGDVFQW 180

Query: 181 CAESWHTDSYFTLFIVMMLYAPAALIVCFTYFNIFRICQQHTKDISERQARFSSQSGETG 240
           CAESWHTDSYFTLFIVMMLYAPAALIVCFTYFNIFRICQQHTKDISERQARFSSQSGETG
Sbjct: 181 CAESWHTDSYFTLFIVMMLYAPAALIVCFTYFNIFRICQQHTKDISERQARFSSQSGETG 240

Query: 241 EVQACPDKRYAMVLFRITSVFYILWLPYIIYFLLESSTGHSNRFASFLTTWLAISNSFCN 300
           EVQACPDKRYAMVLFRITSVFYILWLPYIIYFLLESSTGHSNRFASFLTTWLAISNSFCN
Sbjct: 241 EVQACPDKRYAMVLFRITSVFYILWLPYIIYFLLESSTGHSNRFASFLTTWLAISNSFCN 300

Query: 301 CVIYSLSNSVFQRGLKRLSGAMCTSCASQTTANDPYTVRSKGPLNGCHI 349
           CVIYSLSNSVFQRGLKRLSGAMCTSCASQTTANDPYTVRSKGPLNGCHI
Sbjct: 301 CVIYSLSNSVFQRGLKRLSGAMCTSCASQTTANDPYTVRSKGPLNGCHI 349


>gi|187960055 G protein-coupled receptor 52 [Homo sapiens]
          Length = 361

 Score =  481 bits (1237), Expect = e-136
 Identities = 228/320 (71%), Positives = 268/320 (83%), Gaps = 1/320 (0%)

Query: 8   NQSSHPFCLLAFGYLETVNFCLLEVLIIVFLTVLIISGNIIVIFVFHCAPLLNHHTTSYF 67
           N S    C L FG+   V+ C+ E ++IV LT LII+GN+ VIFVFHCAPLL+H+TTSYF
Sbjct: 20  NVSERHSCPLGFGHYSVVDVCIFETVVIVLLTFLIIAGNLTVIFVFHCAPLLHHYTTSYF 79

Query: 68  IQTMAYADLFVGVSCVVPSLSLLHHPLPVEESLTCQIFGFVVSVLKSVSMASLACISIDR 127
           IQTMAYADLFVGVSC+VP+LSLLH+   V ESLTCQ+FG+++SVLKSVSMA LACIS+DR
Sbjct: 80  IQTMAYADLFVGVSCLVPTLSLLHYSTGVHESLTCQVFGYIISVLKSVSMACLACISVDR 139

Query: 128 YIAITKPLTYNTLVTPWRLRLCIFLIWLYSTLVFLPSFFHWGKPGYHGDVFQWCAESWHT 187
           Y+AITKPL+YN LVTP RLR+CI LIW+YS L+FLPSFF WGKPGYHGD+F+WCA SW T
Sbjct: 140 YLAITKPLSYNQLVTPCRLRICIILIWIYSCLIFLPSFFGWGKPGYHGDIFEWCATSWLT 199

Query: 188 DSYFTLFIVMMLYAPAALIVCFTYFNIFRICQQHTKDISERQARFSSQSGETG-EVQACP 246
            +YFT FIV +LYAPAA +VCFTYF+IF+IC+QHTK+I++R+ARF S   ++  E    P
Sbjct: 200 SAYFTGFIVCLLYAPAAFVVCFTYFHIFKICRQHTKEINDRRARFPSHEVDSSRETGHSP 259

Query: 247 DKRYAMVLFRITSVFYILWLPYIIYFLLESSTGHSNRFASFLTTWLAISNSFCNCVIYSL 306
           D+RYAMVLFRITSVFY+LWLPYIIYFLLESS    N   SFLTTWLAISNSFCNCVIYSL
Sbjct: 260 DRRYAMVLFRITSVFYMLWLPYIIYFLLESSRVLDNPTLSFLTTWLAISNSFCNCVIYSL 319

Query: 307 SNSVFQRGLKRLSGAMCTSC 326
           SNSVF+ GL+RLS  MCTSC
Sbjct: 320 SNSVFRLGLRRLSETMCTSC 339


>gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens]
          Length = 397

 Score = 98.2 bits (243), Expect = 1e-20
 Identities = 87/308 (28%), Positives = 143/308 (46%), Gaps = 29/308 (9%)

Query: 26  NFCL----LEVLIIVFLTVLI---ISGNIIVIFVFHCAPLLNHHTTSYFIQTMAYADLFV 78
           +FCL     ++ I V L VLI   ++GN++V         L +  T+ FI ++A  DL +
Sbjct: 9   SFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRN-LTNCFIVSLAITDLLL 67

Query: 79  GVSCVVPSLSLLHHPLPVEES---LTCQIFGFVVSVLKSVSMASLACISIDRYIAITKPL 135
           G+  V+P  ++  + L  + S   + C I+  +  +L + S+ +L  IS+DRY A+  PL
Sbjct: 68  GL-LVLPFSAI--YQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPL 124

Query: 136 TYNTLVTPWRLRLCIFLIWLYS-TLVFLPSFFHWGKPG--YHGDVFQWCAESWHTDSYFT 192
            Y  LVTP R+ + + LIW+ S TL FL     W        G+      +    + Y  
Sbjct: 125 RYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNEVYGL 184

Query: 193 LFIVMMLYAPAALIVCFTYFNIFRICQQHTKDISERQARFSSQSGETGEVQACPDKRYAM 252
           +  ++  Y P  LI+C TY+ IF++ +   K I+      SS    T       + +  +
Sbjct: 185 VDGLVTFYLP-LLIMCITYYRIFKVARDQAKRIN----HISSWKAAT-----IREHKATV 234

Query: 253 VLFRITSVFYILWLPYIIYFLLESSTGHS--NRFASFLTTWLAISNSFCNCVIYSLSNSV 310
            L  +   F I W PY   F+     G    N     +  WL  +NS  N ++Y+  N  
Sbjct: 235 TLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRD 294

Query: 311 FQRGLKRL 318
           F+ G ++L
Sbjct: 295 FRTGYQQL 302


>gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens]
          Length = 359

 Score = 98.2 bits (243), Expect = 1e-20
 Identities = 87/308 (28%), Positives = 143/308 (46%), Gaps = 29/308 (9%)

Query: 26  NFCL----LEVLIIVFLTVLI---ISGNIIVIFVFHCAPLLNHHTTSYFIQTMAYADLFV 78
           +FCL     ++ I V L VLI   ++GN++V         L +  T+ FI ++A  DL +
Sbjct: 9   SFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRN-LTNCFIVSLAITDLLL 67

Query: 79  GVSCVVPSLSLLHHPLPVEES---LTCQIFGFVVSVLKSVSMASLACISIDRYIAITKPL 135
           G+  V+P  ++  + L  + S   + C I+  +  +L + S+ +L  IS+DRY A+  PL
Sbjct: 68  GL-LVLPFSAI--YQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPL 124

Query: 136 TYNTLVTPWRLRLCIFLIWLYS-TLVFLPSFFHWGKPG--YHGDVFQWCAESWHTDSYFT 192
            Y  LVTP R+ + + LIW+ S TL FL     W        G+      +    + Y  
Sbjct: 125 RYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNEVYGL 184

Query: 193 LFIVMMLYAPAALIVCFTYFNIFRICQQHTKDISERQARFSSQSGETGEVQACPDKRYAM 252
           +  ++  Y P  LI+C TY+ IF++ +   K I+      SS    T       + +  +
Sbjct: 185 VDGLVTFYLP-LLIMCITYYRIFKVARDQAKRIN----HISSWKAAT-----IREHKATV 234

Query: 253 VLFRITSVFYILWLPYIIYFLLESSTGHS--NRFASFLTTWLAISNSFCNCVIYSLSNSV 310
            L  +   F I W PY   F+     G    N     +  WL  +NS  N ++Y+  N  
Sbjct: 235 TLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRD 294

Query: 311 FQRGLKRL 318
           F+ G ++L
Sbjct: 295 FRTGYQQL 302


>gi|24476016 G protein-coupled receptor 161 isoform 2 [Homo sapiens]
          Length = 529

 Score = 95.1 bits (235), Expect = 8e-20
 Identities = 76/314 (24%), Positives = 143/314 (45%), Gaps = 33/314 (10%)

Query: 29  LLEVLIIVFLTVLIISGN-IIVIFVFHCAPLLNHHTTSYFIQTMAYADLFVGVSCVVPSL 87
           + + + I+ +T+ +  GN +IV+ ++  + LL       F  T++   L V V   V + 
Sbjct: 28  ITQFIAIIVITIFVCLGNLVIVVTLYKKSYLLTLSNKFVFSLTLSNFLLSVLVLPFVVTS 87

Query: 88  SLLHHPLPVEESLTCQIFGFVVSVLKSVSMASLACISIDRYIAITKPLTYNTLVTPWRLR 147
           S+      +   + C     +  ++ S SM +L  I+IDRY A+  P+ Y   +T  R  
Sbjct: 88  SIRREW--IFGVVWCNFSALLYLLISSASMLTLGVIAIDRYYAVLYPMVYPMKITGNRAV 145

Query: 148 LCIFLIWLYSTLVFLPSFFHWGKPGYHGDVFQW-CAESWHTDSYFTLF--IVMMLYAPAA 204
           + +  IWL+S +  LP  F W    +  D F+W C  +WH +  +T F  I   L+    
Sbjct: 146 MALVYIWLHSLIGCLPPLFGWSSVEF--DEFKWMCVAAWHREPGYTAFWQIWCALFPFLV 203

Query: 205 LIVCFTYFNIFRICQQHTKDI-----------SERQARFSSQSGET----------GEVQ 243
           ++VC+ +  IFR+ +   + +           ++R  R +S +  +          G V 
Sbjct: 204 MLVCYGF--IFRVARVKARKVHCGTVVIVEEDAQRTGRKNSSTSTSSSGSRRNAFQGVVY 261

Query: 244 ACPDKRYAMVLFRITSVFYILWLPYIIYFLLESSTGHSNRFASFLT--TWLAISNSFCNC 301
           +    +  + +  +   F + W PY++    E+  G S+   S  T  TWL+ +++ C+ 
Sbjct: 262 SANQCKALITILVVLGAFMVTWGPYMVVIASEALWGKSSVSPSLETWATWLSFASAVCHP 321

Query: 302 VIYSLSNSVFQRGL 315
           +IY L N   ++ L
Sbjct: 322 LIYGLWNKTVRKEL 335


>gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens]
          Length = 413

 Score = 94.0 bits (232), Expect = 2e-19
 Identities = 73/294 (24%), Positives = 136/294 (46%), Gaps = 21/294 (7%)

Query: 33  LIIVFLTVLIISGNIIVIFVFHCAPLLNHHTTSYFIQTMAYADLFVGVSCVVPSLSLLHH 92
           +++  + + I+ GN++VI        L    T+YFI ++A ADL +G++ V    + +  
Sbjct: 38  IVMSLIVLAIVFGNVLVITAIAKFERLQT-VTNYFITSLACADLVMGLAVVPFGAAHILM 96

Query: 93  PLPVEESLTCQIFGFVVSVLKSVSMASLACISIDRYIAITKPLTYNTLVTPWRLRLCIFL 152
            +    +  C+ +  +  +  + S+ +L  I++DRY AIT P  Y +L+T  + R+ I +
Sbjct: 97  KMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILM 156

Query: 153 IWLYSTLV-FLPSFFHWGKPGYHGDV----FQWCAESWHTDSYFTLFIVMMLYAPAALIV 207
           +W+ S L  FLP   HW +  +   +     + C + +   +Y     ++  Y P  ++V
Sbjct: 157 VWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMV 216

Query: 208 CFTYFNIFRICQQHTKDISERQARFS-------SQSGETG-----EVQACPDKRYAM-VL 254
            F Y  +F+  ++  + I + + RF         Q G TG       + C  +  A+  L
Sbjct: 217 -FVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTL 275

Query: 255 FRITSVFYILWLPYIIYFLLESSTGHSNRFASF-LTTWLAISNSFCNCVIYSLS 307
             I   F + WLP+ I  ++     +  R   + L  W+   NS  N +IY  S
Sbjct: 276 GIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRS 329


>gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]
          Length = 520

 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 87/327 (26%), Positives = 137/327 (41%), Gaps = 45/327 (13%)

Query: 33  LIIVFLTVLIISGNIIVIFVFHCAPLLNHHT---TSYFIQTMAYADLFVGVSCVVPSLSL 89
           L++    +  I GNI+VI    C    N H    T+YFI  +A ADL +  + +  S +L
Sbjct: 50  LVLGAFILFAIVGNILVILSVAC----NRHLRTPTNYFIVNLAMADLLLSFTVLPFSAAL 105

Query: 90  LHHPLPVEESLTCQIFGFVVSVLKSVSMASLACISIDRYIAITKPLTYNTLVTPWRLRLC 149
                 V   + C I+  V  +  + S+ SL  ISIDRYI +   L Y TLVT  +  L 
Sbjct: 106 EVLGYWVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILA 165

Query: 150 IFLIWLYSTLVFLPSFFHWGKPGYHGDVFQWCAESWHTDSYFTLFIVM-MLYAPAALIVC 208
           +  +W+ ST++ +     W +P  + D      E    + ++ LF  +   Y P A+I+ 
Sbjct: 166 LLSVWVLSTVISIGPLLGWKEPAPNDDKECGVTE----EPFYALFSSLGSFYIPLAVILV 221

Query: 209 FTYFNIFRICQQHTKDISERQARFSSQSGE-----------------TGEVQACPDKRYA 251
             Y  ++ + ++ TK++     +  S S E                 T      P    A
Sbjct: 222 M-YCRVYIVAKRTTKNLEAGVMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSSIA 280

Query: 252 MVLFR-------------ITSVFYILWLPYIIYFLLES--STGHSNRFASFLTTWLAISN 296
           + LF+             +  +F + WLP+ I   L S  ST         +  WL   N
Sbjct: 281 VKLFKFSREKKAAKTLGIVVGMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFWLGYFN 340

Query: 297 SFCNCVIYSLSNSVFQRGLKRLSGAMC 323
           S  N +IY  S+  F+R   R+ G  C
Sbjct: 341 SCLNPIIYPCSSKEFKRAFVRILGCQC 367


>gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]
          Length = 359

 Score = 89.4 bits (220), Expect = 4e-18
 Identities = 90/332 (27%), Positives = 148/332 (44%), Gaps = 37/332 (11%)

Query: 5   LDGNQSSHPFCLLAFGYLETVNFCLLEVLIIVFLTVLI---ISGNIIVIFVFHCAPLLNH 61
           LD N SS       FG +E       +V+++ FL+ +I   I GN++V+        L  
Sbjct: 4   LDANVSSEE----GFGSVE-------KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRK 52

Query: 62  HTTSYFIQTMAYADLFVGVSCVVPSLSLLHHPLPVEESLTCQIFGFVVSVLKSVSMASLA 121
             T+YFI ++A+ADL V V  +      L   + +   + C +   +  +L + S+  L 
Sbjct: 53  IKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLC 112

Query: 122 CISIDRYIAI-TKPLTYNTLVTPWRLRLCIFLIWLYSTLV-FLPSFFHWGKPGYHGDVFQ 179
           CIS+DRY AI  +PL Y   +TP R+ L +   W+  T + FLP    W   G   D+ +
Sbjct: 113 CISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGII-DLIE 171

Query: 180 WCAESWHTDSYFTLFIVMMLYAPAALIVCF---------TYFNIFRICQQHTKDISERQ- 229
               + +++S + +F+V   YA    +V F          Y+ I+   ++H   I   Q 
Sbjct: 172 KRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQR 231

Query: 230 ARFSSQSGETGEVQAC-----PDKRYAMVLFRITSVFYILWLPYIIYFLLE---SSTGHS 281
           A  SS+S      Q        + + A  L  I   F + W P+ +  +++     T   
Sbjct: 232 AGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPG 291

Query: 282 NRFASFLTTWLAISNSFCNCVIYSLSNSVFQR 313
             + +FL  WL   NS  N  +Y+  N  F+R
Sbjct: 292 QVWTAFL--WLGYINSGLNPFLYAFLNKSFRR 321


>gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]
          Length = 428

 Score = 89.4 bits (220), Expect = 4e-18
 Identities = 90/332 (27%), Positives = 148/332 (44%), Gaps = 37/332 (11%)

Query: 5   LDGNQSSHPFCLLAFGYLETVNFCLLEVLIIVFLTVLI---ISGNIIVIFVFHCAPLLNH 61
           LD N SS       FG +E       +V+++ FL+ +I   I GN++V+        L  
Sbjct: 4   LDANVSSEE----GFGSVE-------KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRK 52

Query: 62  HTTSYFIQTMAYADLFVGVSCVVPSLSLLHHPLPVEESLTCQIFGFVVSVLKSVSMASLA 121
             T+YFI ++A+ADL V V  +      L   + +   + C +   +  +L + S+  L 
Sbjct: 53  IKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLC 112

Query: 122 CISIDRYIAI-TKPLTYNTLVTPWRLRLCIFLIWLYSTLV-FLPSFFHWGKPGYHGDVFQ 179
           CIS+DRY AI  +PL Y   +TP R+ L +   W+  T + FLP    W   G   D+ +
Sbjct: 113 CISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGII-DLIE 171

Query: 180 WCAESWHTDSYFTLFIVMMLYAPAALIVCF---------TYFNIFRICQQHTKDISERQ- 229
               + +++S + +F+V   YA    +V F          Y+ I+   ++H   I   Q 
Sbjct: 172 KRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQR 231

Query: 230 ARFSSQSGETGEVQAC-----PDKRYAMVLFRITSVFYILWLPYIIYFLLE---SSTGHS 281
           A  SS+S      Q        + + A  L  I   F + W P+ +  +++     T   
Sbjct: 232 AGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPG 291

Query: 282 NRFASFLTTWLAISNSFCNCVIYSLSNSVFQR 313
             + +FL  WL   NS  N  +Y+  N  F+R
Sbjct: 292 QVWTAFL--WLGYINSGLNPFLYAFLNKSFRR 321


>gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens]
          Length = 360

 Score = 89.4 bits (220), Expect = 4e-18
 Identities = 90/332 (27%), Positives = 148/332 (44%), Gaps = 37/332 (11%)

Query: 5   LDGNQSSHPFCLLAFGYLETVNFCLLEVLIIVFLTVLI---ISGNIIVIFVFHCAPLLNH 61
           LD N SS       FG +E       +V+++ FL+ +I   I GN++V+        L  
Sbjct: 4   LDANVSSEE----GFGSVE-------KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRK 52

Query: 62  HTTSYFIQTMAYADLFVGVSCVVPSLSLLHHPLPVEESLTCQIFGFVVSVLKSVSMASLA 121
             T+YFI ++A+ADL V V  +      L   + +   + C +   +  +L + S+  L 
Sbjct: 53  IKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLC 112

Query: 122 CISIDRYIAI-TKPLTYNTLVTPWRLRLCIFLIWLYSTLV-FLPSFFHWGKPGYHGDVFQ 179
           CIS+DRY AI  +PL Y   +TP R+ L +   W+  T + FLP    W   G   D+ +
Sbjct: 113 CISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGII-DLIE 171

Query: 180 WCAESWHTDSYFTLFIVMMLYAPAALIVCF---------TYFNIFRICQQHTKDISERQ- 229
               + +++S + +F+V   YA    +V F          Y+ I+   ++H   I   Q 
Sbjct: 172 KRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQR 231

Query: 230 ARFSSQSGETGEVQAC-----PDKRYAMVLFRITSVFYILWLPYIIYFLLE---SSTGHS 281
           A  SS+S      Q        + + A  L  I   F + W P+ +  +++     T   
Sbjct: 232 AGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPG 291

Query: 282 NRFASFLTTWLAISNSFCNCVIYSLSNSVFQR 313
             + +FL  WL   NS  N  +Y+  N  F+R
Sbjct: 292 QVWTAFL--WLGYINSGLNPFLYAFLNKSFRR 321


>gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens]
          Length = 387

 Score = 89.4 bits (220), Expect = 4e-18
 Identities = 90/332 (27%), Positives = 148/332 (44%), Gaps = 37/332 (11%)

Query: 5   LDGNQSSHPFCLLAFGYLETVNFCLLEVLIIVFLTVLI---ISGNIIVIFVFHCAPLLNH 61
           LD N SS       FG +E       +V+++ FL+ +I   I GN++V+        L  
Sbjct: 4   LDANVSSEE----GFGSVE-------KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRK 52

Query: 62  HTTSYFIQTMAYADLFVGVSCVVPSLSLLHHPLPVEESLTCQIFGFVVSVLKSVSMASLA 121
             T+YFI ++A+ADL V V  +      L   + +   + C +   +  +L + S+  L 
Sbjct: 53  IKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLC 112

Query: 122 CISIDRYIAI-TKPLTYNTLVTPWRLRLCIFLIWLYSTLV-FLPSFFHWGKPGYHGDVFQ 179
           CIS+DRY AI  +PL Y   +TP R+ L +   W+  T + FLP    W   G   D+ +
Sbjct: 113 CISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGII-DLIE 171

Query: 180 WCAESWHTDSYFTLFIVMMLYAPAALIVCF---------TYFNIFRICQQHTKDISERQ- 229
               + +++S + +F+V   YA    +V F          Y+ I+   ++H   I   Q 
Sbjct: 172 KRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQR 231

Query: 230 ARFSSQSGETGEVQAC-----PDKRYAMVLFRITSVFYILWLPYIIYFLLE---SSTGHS 281
           A  SS+S      Q        + + A  L  I   F + W P+ +  +++     T   
Sbjct: 232 AGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPG 291

Query: 282 NRFASFLTTWLAISNSFCNCVIYSLSNSVFQR 313
             + +FL  WL   NS  N  +Y+  N  F+R
Sbjct: 292 QVWTAFL--WLGYINSGLNPFLYAFLNKSFRR 321


>gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens]
          Length = 378

 Score = 89.4 bits (220), Expect = 4e-18
 Identities = 90/332 (27%), Positives = 148/332 (44%), Gaps = 37/332 (11%)

Query: 5   LDGNQSSHPFCLLAFGYLETVNFCLLEVLIIVFLTVLI---ISGNIIVIFVFHCAPLLNH 61
           LD N SS       FG +E       +V+++ FL+ +I   I GN++V+        L  
Sbjct: 4   LDANVSSEE----GFGSVE-------KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRK 52

Query: 62  HTTSYFIQTMAYADLFVGVSCVVPSLSLLHHPLPVEESLTCQIFGFVVSVLKSVSMASLA 121
             T+YFI ++A+ADL V V  +      L   + +   + C +   +  +L + S+  L 
Sbjct: 53  IKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLC 112

Query: 122 CISIDRYIAI-TKPLTYNTLVTPWRLRLCIFLIWLYSTLV-FLPSFFHWGKPGYHGDVFQ 179
           CIS+DRY AI  +PL Y   +TP R+ L +   W+  T + FLP    W   G   D+ +
Sbjct: 113 CISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGII-DLIE 171

Query: 180 WCAESWHTDSYFTLFIVMMLYAPAALIVCF---------TYFNIFRICQQHTKDISERQ- 229
               + +++S + +F+V   YA    +V F          Y+ I+   ++H   I   Q 
Sbjct: 172 KRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQR 231

Query: 230 ARFSSQSGETGEVQAC-----PDKRYAMVLFRITSVFYILWLPYIIYFLLE---SSTGHS 281
           A  SS+S      Q        + + A  L  I   F + W P+ +  +++     T   
Sbjct: 232 AGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPG 291

Query: 282 NRFASFLTTWLAISNSFCNCVIYSLSNSVFQR 313
             + +FL  WL   NS  N  +Y+  N  F+R
Sbjct: 292 QVWTAFL--WLGYINSGLNPFLYAFLNKSFRR 321


>gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens]
          Length = 388

 Score = 89.4 bits (220), Expect = 4e-18
 Identities = 90/332 (27%), Positives = 148/332 (44%), Gaps = 37/332 (11%)

Query: 5   LDGNQSSHPFCLLAFGYLETVNFCLLEVLIIVFLTVLI---ISGNIIVIFVFHCAPLLNH 61
           LD N SS       FG +E       +V+++ FL+ +I   I GN++V+        L  
Sbjct: 4   LDANVSSEE----GFGSVE-------KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRK 52

Query: 62  HTTSYFIQTMAYADLFVGVSCVVPSLSLLHHPLPVEESLTCQIFGFVVSVLKSVSMASLA 121
             T+YFI ++A+ADL V V  +      L   + +   + C +   +  +L + S+  L 
Sbjct: 53  IKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLC 112

Query: 122 CISIDRYIAI-TKPLTYNTLVTPWRLRLCIFLIWLYSTLV-FLPSFFHWGKPGYHGDVFQ 179
           CIS+DRY AI  +PL Y   +TP R+ L +   W+  T + FLP    W   G   D+ +
Sbjct: 113 CISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGII-DLIE 171

Query: 180 WCAESWHTDSYFTLFIVMMLYAPAALIVCF---------TYFNIFRICQQHTKDISERQ- 229
               + +++S + +F+V   YA    +V F          Y+ I+   ++H   I   Q 
Sbjct: 172 KRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQR 231

Query: 230 ARFSSQSGETGEVQAC-----PDKRYAMVLFRITSVFYILWLPYIIYFLLE---SSTGHS 281
           A  SS+S      Q        + + A  L  I   F + W P+ +  +++     T   
Sbjct: 232 AGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPG 291

Query: 282 NRFASFLTTWLAISNSFCNCVIYSLSNSVFQR 313
             + +FL  WL   NS  N  +Y+  N  F+R
Sbjct: 292 QVWTAFL--WLGYINSGLNPFLYAFLNKSFRR 321


>gi|222080109 orexin receptor 2 [Homo sapiens]
          Length = 444

 Score = 89.0 bits (219), Expect = 6e-18
 Identities = 91/338 (26%), Positives = 151/338 (44%), Gaps = 54/338 (15%)

Query: 29  LLEVLIIVFLTVLIISGNIIVIFVFHCAPLLNHH---TTSYFIQTMAYADLFVGVSCVVP 85
           L+   IIVF+  LI  GN++V      A   NHH    T+YFI  ++ AD+ V ++C+  
Sbjct: 57  LIAGYIIVFVVALI--GNVLVCV----AVWKNHHMRTVTNYFIVNLSLADVLVTITCLPA 110

Query: 86  SLSLLHHPLPVEESLTCQIFGFVVSVLKSVSMASLACISIDRYIAITKPLTYNTLVTPWR 145
           +L +            C++  ++ +V  SVS+ +L+CI++DR+ AI  PL + +  T  R
Sbjct: 111 TLVVDITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKS--TAKR 168

Query: 146 LRLCIFLIWLYSTLVFLPSFF----HWGKPGYHG--DVFQWCAESW----HTDSYFTLFI 195
            R  I +IW+ S ++ +P           PG      +F  C E W    +   Y   F 
Sbjct: 169 ARNSIVIIWIVSCIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFF 228

Query: 196 VMMLYAPAALIVCFTYFNIFR--ICQQ--HTKDISER------------------QARFS 233
           ++   AP  L+V   Y  IFR   C+Q   T  + +R                  ++R S
Sbjct: 229 LVTYMAPLCLMV-LAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMS 287

Query: 234 SQSGETGEVQACPDKRYAMVLFRITSVFYILWLPYIIYFLLESSTG-------HSNRFAS 286
           + + E  +++A   ++ A +L  +  VF I +LP  I  +L+   G           +A 
Sbjct: 288 AVAAEIKQIRA--RRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAW 345

Query: 287 F-LTTWLAISNSFCNCVIYSLSNSVFQRGLKRLSGAMC 323
           F  + WL  +NS  N +IY+  +  F+   K      C
Sbjct: 346 FTFSHWLVYANSAANPIIYNFLSGKFREEFKAAFSCCC 383


>gi|4557265 beta-1-adrenergic receptor [Homo sapiens]
          Length = 477

 Score = 89.0 bits (219), Expect = 6e-18
 Identities = 92/371 (24%), Positives = 149/371 (40%), Gaps = 75/371 (20%)

Query: 33  LIIVFLTVLIISGNIIVIFVFHCAPLLNHHTTSYFIQTMAYADLFVGVSCVVPSLSLLHH 92
           L++  + +LI++GN++VI      P L    T+ FI ++A ADL +G+  V    +++  
Sbjct: 63  LLMALIVLLIVAGNVLVIVAIAKTPRLQT-LTNLFIMSLASADLVMGLLVVPFGATIVVW 121

Query: 93  PLPVEESLTCQIFGFVVSVLKSVSMASLACISIDRYIAITKPLTYNTLVTPWRLRLCIFL 152
                 S  C+++  V  +  + S+ +L  I++DRY+AIT P  Y +L+T  R R  +  
Sbjct: 122 GRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARGLVCT 181

Query: 153 IWLYSTLV-FLPSFFHWGKPGYHGDVFQWCAES-----WHTDSYFTLFIVMMLYAPAALI 206
           +W  S LV FLP   HW           W AES      + D     F+    YA A+ +
Sbjct: 182 VWAISALVSFLPILMHW-----------WRAESDEARRCYNDPKCCDFVTNRAYAIASSV 230

Query: 207 V---------CFTYFNIFRICQQHTKDISERQARFSS----------------------- 234
           V          F Y  +FR  Q+  K I   + RF                         
Sbjct: 231 VSFYVPLCIMAFVYLRVFREAQKQVKKIDSCERRFLGGPARPPSPSPSPVPAPAPPPGPP 290

Query: 235 -----------QSGETGE-----VQACPDKRYAMVLFRITSVFYILWLPYIIYFLLESST 278
                       +G  G+     + A  +++    L  I  VF + WLP+ +  ++++  
Sbjct: 291 RPAAAAATAPLANGRAGKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFH 350

Query: 279 GH--SNRFASFLTTWLAISNSFCNCVIYSLSNSVFQRGLKRLSGAMCTSCASQTTANDPY 336
                +R   F   WL  +NS  N +IY  S        K   G +C  CA +       
Sbjct: 351 RELVPDRLFVFF-NWLGYANSAFNPIIYCRSPDF----RKAFQGLLC--CARRAARRRHA 403

Query: 337 TVRSKGPLNGC 347
           T   +   +GC
Sbjct: 404 THGDRPRASGC 414


>gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens]
          Length = 402

 Score = 85.5 bits (210), Expect = 6e-17
 Identities = 91/345 (26%), Positives = 148/345 (42%), Gaps = 49/345 (14%)

Query: 5   LDGNQSSHPFCLLAFGYLETVNFCLLEVLIIVFLTVLI---ISGNIIVIFVFHCAPLLNH 61
           LD N SS       FG +E       +V+++ FL+ +I   I GN++V+        L  
Sbjct: 4   LDANVSSEE----GFGSVE-------KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRK 52

Query: 62  HTTSYFIQTMAYADLFVGVSCVVPSLSLLHHPLPVEESLTCQIFGFVVSVLKSVSMASLA 121
             T+YFI ++A+ADL V V  +      L   + +   + C +   +  +L + S+  L 
Sbjct: 53  IKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLC 112

Query: 122 CISIDRYIAI-TKPLTYNTLVTPWRLRLCIFLIWLYSTLV-FLPSFFHWGKPG---YHGD 176
           CIS+DRY AI  +PL Y   +TP R+ L +   W+  T + FLP    W   G       
Sbjct: 113 CISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLERS 172

Query: 177 VFQWCAESWH----------TDSYFTLFIVMMLYAPAALIVCF---------TYFNIFRI 217
           + Q   + +H          ++S + +F+V   YA    +V F          Y+ I+  
Sbjct: 173 LNQGLGQDFHAIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVT 232

Query: 218 CQQHTKDISERQ-ARFSSQSGETGEVQAC-----PDKRYAMVLFRITSVFYILWLPYIIY 271
            ++H   I   Q A  SS+S      Q        + + A  L  I   F + W P+ + 
Sbjct: 233 AKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVT 292

Query: 272 FLLE---SSTGHSNRFASFLTTWLAISNSFCNCVIYSLSNSVFQR 313
            +++     T     + +FL  WL   NS  N  +Y+  N  F+R
Sbjct: 293 NIVDPFIDYTVPGQVWTAFL--WLGYINSGLNPFLYAFLNKSFRR 335


>gi|4501953 adenosine A3 receptor isoform 2 [Homo sapiens]
          Length = 318

 Score = 85.1 bits (209), Expect = 8e-17
 Identities = 79/286 (27%), Positives = 125/286 (43%), Gaps = 24/286 (8%)

Query: 36  VFLTVLIISGNIIVIFVFHCAPLLNHHTTSYFIQTMAYADLFVGVS----CVVPSLSLLH 91
           +F+ +  I GN++VI V    P L   TT YFI ++A AD+ VGV      +V SL +  
Sbjct: 20  IFIGLCAIVGNVLVICVVKLNPSLQT-TTFYFIVSLALADIAVGVLVMPLAIVVSLGITI 78

Query: 92  HPLPVEESLTCQIFGFVVSVLKSVSMASLACISIDRYIAITKPLTYNTLVTPWRLRLCIF 151
           H        +C     ++ +    S+ SL  I++DRY+ +   + Y  + T  R+ L + 
Sbjct: 79  H------FYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALG 132

Query: 152 LIWLYSTLVFLPSFFHWG---KPGYHGDV-FQWCA-ESWHTDSYFTLFIVMMLYAPAALI 206
           L WL S LV L   F W       YH +V F  C   S     Y   F  +       ++
Sbjct: 133 LCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVV 192

Query: 207 VCFTYFNIFRICQQHTKDISERQARFSSQSGETGEVQACPDKRYAMVLFRITSVFYILWL 266
           +C  Y +IF I       I  + +   S S ETG      + + A  LF +  +F + WL
Sbjct: 193 MCAIYLDIFYI-------IRNKLSLNLSNSKETGAFYG-REFKTAKSLFLVLFLFALSWL 244

Query: 267 PYIIYFLLESSTGHSNRFASFLTTWLAISNSFCNCVIYSLSNSVFQ 312
           P  I   +    G   +   ++   L+ +NS  N ++Y+     F+
Sbjct: 245 PLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFK 290


>gi|110618256 trace amine associated receptor 9 [Homo sapiens]
          Length = 348

 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 85/313 (27%), Positives = 136/313 (43%), Gaps = 27/313 (8%)

Query: 34  IIVFLTVLIISGNIIV-IFVFHCAPLLNHHTTSYFIQTMAYADLFVGVSCVVPSLSLLHH 92
           ++ F  VL   GN++V I + H   L  H  T++ I ++A AD  VGV+ V+P  +    
Sbjct: 38  VLGFGAVLAAFGNLLVMIAILHFKQL--HTPTNFLIASLACADFLVGVT-VMPFST---- 90

Query: 93  PLPVEESLTCQIFG-----FVVSVLKSVSMASL---ACISIDRYIAITKPLTYNTLVTPW 144
              V    +C  FG     F      S   ASL    CIS+DRYIA+T PLTY T  T  
Sbjct: 91  ---VRSVESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAVTDPLTYPTKFTVS 147

Query: 145 RLRLCIFLIWLYSTLVFLPSFFHWG--KPGYHGDVFQ-WCAESWHT--DSYFTLFIVMML 199
              +CI L W +S + +  S F+ G  + G    V    C        +  + L   ++ 
Sbjct: 148 VSGICIVLSWFFS-VTYSFSIFYTGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFLLF 206

Query: 200 YAPAALIVCFTYFNIFRICQQHTKDISERQARFSSQSGETGEVQACPDKRYAMVLFRITS 259
           + P   +V F Y  IF + +   + I    ++  S S    E  A  +++ A  L    +
Sbjct: 207 FIPNVAMV-FIYSKIFLVAKHQARKIESTASQAQSSSESYKERVAKRERKAAKTLGIAMA 265

Query: 260 VFYILWLPYIIYFLLESSTGH-SNRFASFLTTWLAISNSFCNCVIYSLSNSVFQRGLKRL 318
            F + WLPY++  ++++     +  +   +  W    NS  N +IY+     F + +K +
Sbjct: 266 AFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCVYYNSAMNPLIYAFFYQWFGKAIKLI 325

Query: 319 SGAMCTSCASQTT 331
                    S TT
Sbjct: 326 VSGKVLRTDSSTT 338


>gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens]
          Length = 408

 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 81/325 (24%), Positives = 132/325 (40%), Gaps = 46/325 (14%)

Query: 34  IIVFLTVLIISGNIIVIFVFHCAPLLNHHTTSYFIQTMAYADLFVGVSCVVPSLSLL--- 90
           ++    +  + GN++VI      P L    T+ F+ ++A ADL +G+  V P+ +L    
Sbjct: 43  LLALAVLATVGGNLLVIVAIAWTPRLQT-MTNVFVTSLAAADLVMGLLVVPPAATLALTG 101

Query: 91  HHPLPVEESLTCQIFGFVVSVLKSVSMASLACISIDRYIAITKPLTYNTLVTPWRLRLCI 150
           H PL    +  C+++  V  +  + S+ +L  +++DRY+A+T PL Y  LVT    R  +
Sbjct: 102 HWPLG---ATGCELWTSVDVLCVTASIETLCALAVDRYLAVTNPLRYGALVTKRCARTAV 158

Query: 151 FLIWLYSTLV-FLPSFFHWGKPGYHGDVFQW-----CAESWHTDSYFTLFIVMMLYAPAA 204
            L+W+ S  V F P    W + G   +  +      C        Y  L   +  Y P  
Sbjct: 159 VLVWVVSAAVSFAPIMSQWWRVGADAEAQRCHSNPRCCAFASNMPYVLLSSSVSFYLP-L 217

Query: 205 LIVCFTYFNIFRICQQHTKDISERQARFSSQSGETGE-----------------VQAC-- 245
           L++ F Y  +F +  +  + +     RF  +                       V AC  
Sbjct: 218 LVMLFVYARVFVVATRQLRLLRGELGRFPPEESPPAPSRSLAPAPVGTCAPPEGVPACGR 277

Query: 246 --------PDKRYAMVLFRITSVFYILWLPYIIYFLLESSTGHS--NRFASFLTTWLAIS 295
                    + R    L  I   F + WLP+ +  +L +  G S     A     WL  +
Sbjct: 278 RPARLLPLREHRALCTLGLIMGTFTLCWLPFFLANVLRALGGPSLVPGPAFLALNWLGYA 337

Query: 296 NSFCNCVIYSLS---NSVFQRGLKR 317
           NS  N +IY  S    S F+R L R
Sbjct: 338 NSAFNPLIYCRSPDFRSAFRRLLCR 362


>gi|28173558 trace amine associated receptor 6 [Homo sapiens]
          Length = 345

 Score = 83.2 bits (204), Expect = 3e-16
 Identities = 81/304 (26%), Positives = 126/304 (41%), Gaps = 37/304 (12%)

Query: 33  LIIVFLTVLIISGNIIV-IFVFHCAPLLNHHTTSYFIQTMAYADLFVGVSCVVPSLSLLH 91
           ++  F  VL + GN++V I + H   L  H  T++ + ++A AD  VGV+ +  S+    
Sbjct: 37  IVFGFGAVLAVFGNLLVMISILHFKQL--HSPTNFLVASLACADFLVGVTVMPFSM---- 90

Query: 92  HPLPVEESLTCQIFGFVVSVLKSV--------SMASLACISIDRYIAITKPLTYNTLVTP 143
               V    +C  FG       +         S+  L  ISIDRYIA+T PL Y T  T 
Sbjct: 91  ----VRTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIAVTDPLVYPTKFTV 146

Query: 144 WRLRLCIFLIW----LYSTLVFLPSFFHWGKPGYH------GDVFQWCAESWHTDSYFTL 193
               +CI + W    +YS  VF    +  G           G       ++W    + + 
Sbjct: 147 SVSGICISVSWILPLMYSGAVFYTGVYDDGLEELSDALNCIGGCQTVVNQNWVLTDFLSF 206

Query: 194 FIVMMLYAPAALIVCFTYFNIFRICQQHTKDISERQARFSSQSGETGEVQACPDKRYAMV 253
           FI          I+   Y NIF + ++  K I    ++  S S       A  +++ A  
Sbjct: 207 FI-------PTFIMIILYGNIFLVARRQAKKIENTGSKTESSSESYKARVARRERKAAKT 259

Query: 254 LFRITSVFYILWLPYIIYFLLESSTGHSNRFASF-LTTWLAISNSFCNCVIYSLSNSVFQ 312
           L      F I WLPY I  L+++  G       + +  W A  NS  N +IY+L    F+
Sbjct: 260 LGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCAYYNSAMNPLIYALFYPWFR 319

Query: 313 RGLK 316
           + +K
Sbjct: 320 KAIK 323


>gi|167000885 galanin receptor 1 [Homo sapiens]
          Length = 349

 Score = 81.6 bits (200), Expect = 9e-16
 Identities = 77/301 (25%), Positives = 125/301 (41%), Gaps = 24/301 (7%)

Query: 26  NFCLLEVLIIVFLTVLIISGNIIVIFVF-HCAPLLNHHTTSYFIQTMAYADLFVGVSCVV 84
           NF  L V  ++F   L + GN +VI V     P     TT+ FI  ++ ADL   + C+ 
Sbjct: 33  NFVTLVVFGLIF--ALGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIP 90

Query: 85  PSLSLLHHPLPVEESLTCQIFGFVVSVLKSVSMASLACISIDRYIAITKPLTYNTLVTPW 144
              ++   P  V  +  C+   +  +V   VS+ +LA +S+DRY+AI      ++L    
Sbjct: 91  FQATVYALPTWVLGAFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRRSSSLRVSR 150

Query: 145 RLRLCIFLIWLYSTLVFLPSFFHWGKPGYHGDVFQWCAESWHTDSYFTLFIVMML---YA 201
              L +  IW  S  +  P  +H G          +C E W    +   ++V      Y 
Sbjct: 151 NALLGVGCIWALSIAMASPVAYHQGLFHPRASNQTFCWEQWPDPRHKKAYVVCTFVFGYL 210

Query: 202 PAALIVCFTYFNIFRICQQHTKDISERQARFSSQSGETGEVQACPDKRYAMVLFRITSVF 261
              L++CF Y  +     +  K++S++                   K+ A  +  +  VF
Sbjct: 211 LPLLLICFCYAKVLNHLHKKLKNMSKK--------------SEASKKKTAQTVLVVVVVF 256

Query: 262 YILWLPYIIYFLLESSTGHSNRFASFL----TTWLAISNSFCNCVIYSLSNSVFQRGLKR 317
            I WLP+ I  L           ASFL       LA SNS  N +IY+  +  F++  K+
Sbjct: 257 GISWLPHHIIHLWAEFGVFPLTPASFLFRITAHCLAYSNSSVNPIIYAFLSENFRKAYKQ 316

Query: 318 L 318
           +
Sbjct: 317 V 317


>gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens]
          Length = 455

 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 86/358 (24%), Positives = 145/358 (40%), Gaps = 40/358 (11%)

Query: 5   LDGNQSSHPFCLLAFGYLETVNFCLLEVLIIVFLTVLIISGNIIVIFVFHCAPLLNHHTT 64
           L GN S    C      +      LL V I+  L +  + GNI+VI    C   L H  T
Sbjct: 4   LSGNASDSSNCTQPPAPVNISKAILLGV-ILGGLILFGVLGNILVILSVACHRHL-HSVT 61

Query: 65  SYFIQTMAYADLFVGVSCVVPSLSLLHHPLPVEE--SLTCQIFGFVVSVLKSVSMASLAC 122
            Y+I  +A ADL +  S V+P  S +   L       + C I+  V  +  + S+  L  
Sbjct: 62  HYYIVNLAVADLLL-TSTVLP-FSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCI 119

Query: 123 ISIDRYIAITKPLTYNTLVTPWRLRLCIFLIWLYSTLVFLPSFFHWGKPGYHGDVFQWCA 182
           ISIDRYI ++ PL Y T+VT  R  + +  +W  S ++ +   F W +P    +      
Sbjct: 120 ISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDETICQIN 179

Query: 183 ESWHTDSYFTLFIVMMLYAPAALIVCFTYFNIFRICQQHTK--------------DISER 228
           E      Y     +   Y P A+I+   Y  ++ + ++ ++               ++ R
Sbjct: 180 EE---PGYVLFSALGSFYLPLAIILVM-YCRVYVVAKRESRGLKSGLKTDKSDSEQVTLR 235

Query: 229 QARFSSQSGETGEVQA-------------CPDKRYAMVLFRITSVFYILWLPYIIYFLLE 275
             R ++ +G +G   A               +K+ A  L  +   F + WLP+ +   + 
Sbjct: 236 IHRKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIG 295

Query: 276 S--STGHSNRFASFLTTWLAISNSFCNCVIYSLSNSVFQRGLKRLSGAMCTSCASQTT 331
           S       +     +  WL   NS  N +IY  S+  F++  + +    C  C  Q++
Sbjct: 296 SFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCL-CRKQSS 352


>gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens]
          Length = 466

 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 86/358 (24%), Positives = 145/358 (40%), Gaps = 40/358 (11%)

Query: 5   LDGNQSSHPFCLLAFGYLETVNFCLLEVLIIVFLTVLIISGNIIVIFVFHCAPLLNHHTT 64
           L GN S    C      +      LL V I+  L +  + GNI+VI    C   L H  T
Sbjct: 4   LSGNASDSSNCTQPPAPVNISKAILLGV-ILGGLILFGVLGNILVILSVACHRHL-HSVT 61

Query: 65  SYFIQTMAYADLFVGVSCVVPSLSLLHHPLPVEE--SLTCQIFGFVVSVLKSVSMASLAC 122
            Y+I  +A ADL +  S V+P  S +   L       + C I+  V  +  + S+  L  
Sbjct: 62  HYYIVNLAVADLLL-TSTVLP-FSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCI 119

Query: 123 ISIDRYIAITKPLTYNTLVTPWRLRLCIFLIWLYSTLVFLPSFFHWGKPGYHGDVFQWCA 182
           ISIDRYI ++ PL Y T+VT  R  + +  +W  S ++ +   F W +P    +      
Sbjct: 120 ISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDETICQIN 179

Query: 183 ESWHTDSYFTLFIVMMLYAPAALIVCFTYFNIFRICQQHTK--------------DISER 228
           E      Y     +   Y P A+I+   Y  ++ + ++ ++               ++ R
Sbjct: 180 EE---PGYVLFSALGSFYLPLAIILVM-YCRVYVVAKRESRGLKSGLKTDKSDSEQVTLR 235

Query: 229 QARFSSQSGETGEVQA-------------CPDKRYAMVLFRITSVFYILWLPYIIYFLLE 275
             R ++ +G +G   A               +K+ A  L  +   F + WLP+ +   + 
Sbjct: 236 IHRKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIG 295

Query: 276 S--STGHSNRFASFLTTWLAISNSFCNCVIYSLSNSVFQRGLKRLSGAMCTSCASQTT 331
           S       +     +  WL   NS  N +IY  S+  F++  + +    C  C  Q++
Sbjct: 296 SFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCL-CRKQSS 352


>gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens]
          Length = 475

 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 86/358 (24%), Positives = 145/358 (40%), Gaps = 40/358 (11%)

Query: 5   LDGNQSSHPFCLLAFGYLETVNFCLLEVLIIVFLTVLIISGNIIVIFVFHCAPLLNHHTT 64
           L GN S    C      +      LL V I+  L +  + GNI+VI    C   L H  T
Sbjct: 4   LSGNASDSSNCTQPPAPVNISKAILLGV-ILGGLILFGVLGNILVILSVACHRHL-HSVT 61

Query: 65  SYFIQTMAYADLFVGVSCVVPSLSLLHHPLPVEE--SLTCQIFGFVVSVLKSVSMASLAC 122
            Y+I  +A ADL +  S V+P  S +   L       + C I+  V  +  + S+  L  
Sbjct: 62  HYYIVNLAVADLLL-TSTVLP-FSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCI 119

Query: 123 ISIDRYIAITKPLTYNTLVTPWRLRLCIFLIWLYSTLVFLPSFFHWGKPGYHGDVFQWCA 182
           ISIDRYI ++ PL Y T+VT  R  + +  +W  S ++ +   F W +P    +      
Sbjct: 120 ISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDETICQIN 179

Query: 183 ESWHTDSYFTLFIVMMLYAPAALIVCFTYFNIFRICQQHTK--------------DISER 228
           E      Y     +   Y P A+I+   Y  ++ + ++ ++               ++ R
Sbjct: 180 EE---PGYVLFSALGSFYLPLAIILVM-YCRVYVVAKRESRGLKSGLKTDKSDSEQVTLR 235

Query: 229 QARFSSQSGETGEVQA-------------CPDKRYAMVLFRITSVFYILWLPYIIYFLLE 275
             R ++ +G +G   A               +K+ A  L  +   F + WLP+ +   + 
Sbjct: 236 IHRKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIG 295

Query: 276 S--STGHSNRFASFLTTWLAISNSFCNCVIYSLSNSVFQRGLKRLSGAMCTSCASQTT 331
           S       +     +  WL   NS  N +IY  S+  F++  + +    C  C  Q++
Sbjct: 296 SFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCL-CRKQSS 352


>gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens]
          Length = 429

 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 86/358 (24%), Positives = 145/358 (40%), Gaps = 40/358 (11%)

Query: 5   LDGNQSSHPFCLLAFGYLETVNFCLLEVLIIVFLTVLIISGNIIVIFVFHCAPLLNHHTT 64
           L GN S    C      +      LL V I+  L +  + GNI+VI    C   L H  T
Sbjct: 4   LSGNASDSSNCTQPPAPVNISKAILLGV-ILGGLILFGVLGNILVILSVACHRHL-HSVT 61

Query: 65  SYFIQTMAYADLFVGVSCVVPSLSLLHHPLPVEE--SLTCQIFGFVVSVLKSVSMASLAC 122
            Y+I  +A ADL +  S V+P  S +   L       + C I+  V  +  + S+  L  
Sbjct: 62  HYYIVNLAVADLLL-TSTVLP-FSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCI 119

Query: 123 ISIDRYIAITKPLTYNTLVTPWRLRLCIFLIWLYSTLVFLPSFFHWGKPGYHGDVFQWCA 182
           ISIDRYI ++ PL Y T+VT  R  + +  +W  S ++ +   F W +P    +      
Sbjct: 120 ISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDETICQIN 179

Query: 183 ESWHTDSYFTLFIVMMLYAPAALIVCFTYFNIFRICQQHTK--------------DISER 228
           E      Y     +   Y P A+I+   Y  ++ + ++ ++               ++ R
Sbjct: 180 EE---PGYVLFSALGSFYLPLAIILVM-YCRVYVVAKRESRGLKSGLKTDKSDSEQVTLR 235

Query: 229 QARFSSQSGETGEVQA-------------CPDKRYAMVLFRITSVFYILWLPYIIYFLLE 275
             R ++ +G +G   A               +K+ A  L  +   F + WLP+ +   + 
Sbjct: 236 IHRKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIG 295

Query: 276 S--STGHSNRFASFLTTWLAISNSFCNCVIYSLSNSVFQRGLKRLSGAMCTSCASQTT 331
           S       +     +  WL   NS  N +IY  S+  F++  + +    C  C  Q++
Sbjct: 296 SFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCL-CRKQSS 352


>gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo
           sapiens]
          Length = 440

 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 74/314 (23%), Positives = 135/314 (42%), Gaps = 26/314 (8%)

Query: 41  LIISGNIIVIFVFHCAPLLNHHTTSYFIQTMAYADLFVGVSCVVPS-LSLLHHPLPVEES 99
           L  + N ++I +    P L + T+++F+ ++  +DL VG+  + P+ L+ L+    +   
Sbjct: 39  LTAAANSLLIALICTQPALRN-TSNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARG 97

Query: 100 LTCQIFGFVVSVLKSVSMASLACISIDRYIAITKPLTYNTLVTPWRLRLCIFLIWLYSTL 159
           L C ++     +  S S+ +L  IS+DRY+ I  PL Y   +TP R    +   W  + L
Sbjct: 98  L-CLLWTAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAAL 156

Query: 160 V-FLPSFFHWGKPGYHGDVFQWCAESWHTDSYFTLFIVMMLYAPAALIVCFTYFNIFRIC 218
             FLP    W + G+             +  +  +   +  + P+  I CFTY  I    
Sbjct: 157 ASFLPLLLGWHELGHARPPVPGQCRLLASLPFVLVASGLTFFLPSGAI-CFTYCRILLAA 215

Query: 219 QQHTKDISERQARFSSQSGETGEVQACP-------DKR------------YAMVLFRITS 259
           ++    ++      +SQ+ ET +V   P       D R             ++ L  +  
Sbjct: 216 RKQAVQVASLTTGMASQASETLQVPRTPRPGVESADSRRLATKHSRKALKASLTLGILLG 275

Query: 260 VFYILWLPYIIYFLLESSTGHSNRFASFLTTWLAISNSFCNCVIYSLSNSVFQRGLKRLS 319
           +F++ WLP+ +  ++++     +     + TWL   NS  N +IY L    F+R L R  
Sbjct: 276 MFFVTWLPFFVANIVQAVCDCISPGLFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRF- 334

Query: 320 GAMCTSCASQTTAN 333
              C  C  +  A+
Sbjct: 335 -LPCPRCPRERQAS 347


>gi|16751917 trace amine associated receptor 8 [Homo sapiens]
          Length = 342

 Score = 79.3 bits (194), Expect = 5e-15
 Identities = 83/316 (26%), Positives = 136/316 (43%), Gaps = 41/316 (12%)

Query: 37  FLTVLIISGNIIVIF-VFHCAPLLNHHTTSYFIQTMAYADLFVGVSCVVPSLSLLHHPLP 95
           F ++L + GN++V+  V H   L  H  T++ I ++A AD  VGV+ ++ S+        
Sbjct: 40  FGSLLAVFGNLLVMTSVLHFKQL--HSPTNFLIASLACADFLVGVTVMLFSM-------- 89

Query: 96  VEESLTCQIFGFVVSVLKSV--------SMASLACISIDRYIAITKPLTYNTLVTPWRLR 147
           V    +C  FG     L S         S+  L  I IDRYI +T PL Y T  T     
Sbjct: 90  VRTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFICIDRYIVVTDPLVYATKFTVSVSG 149

Query: 148 LCIFLIWL----YSTLVFLPSFFHWGKPGYHGDVFQWCAESWH-------TDSYFTLFIV 196
           +CI + W+    YS  VF          G + D  +    + +         S   + I 
Sbjct: 150 ICISVSWILPLTYSGAVFY--------TGVNDDGLEELVSALNCVGGCQIIVSQGWVLID 201

Query: 197 MMLYAPAALIVCFTYFNIFRICQQHTKDISERQARFSSQSGETGEVQACPDKRYAMVLFR 256
            +L+    L++   Y  IF I +Q    I    ++  S S E+ +++    +R A     
Sbjct: 202 FLLFFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVES-SSESYKIRVAKRERKAAKTLG 260

Query: 257 ITSV-FYILWLPYIIYFLLESSTGH-SNRFASFLTTWLAISNSFCNCVIYSLSNSVFQRG 314
           +T + F I WLPY +  L+++  G  +  +   +  W A  NS  N +IY+L    F++ 
Sbjct: 261 VTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSAYYNSAMNPLIYALFYPWFRKA 320

Query: 315 LKRLSGAMCTSCASQT 330
           +K +        +S T
Sbjct: 321 IKLILSGDVLKASSST 336


>gi|16604258 neuropeptide FF receptor 2 isoform 2 [Homo sapiens]
          Length = 420

 Score = 77.8 bits (190), Expect = 1e-14
 Identities = 78/349 (22%), Positives = 139/349 (39%), Gaps = 46/349 (13%)

Query: 21  YLETVNFCLLEVLIIVFLTVLIISGNIIVIFVFHCAPLLNHHTTSYFIQTMAYADLFVGV 80
           YL       + ++    +  L + GN +V F+      + H  T+ FI  +A +DL VG+
Sbjct: 38  YLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHM-HTVTNLFILNLAISDLLVGI 96

Query: 81  SCVVPSLSLLHHPL---PVEESLTCQIFGFVVSVLKSVSMASLACISIDRYIAITKPLTY 137
            C+   ++LL + +   P   ++ C+I G V  +  + S+ +L  I++DR+  +  P  +
Sbjct: 97  FCM--PITLLDNIIAGWPFGNTM-CKISGLVQGISVAASVFTLVAIAVDRFQCVVYP--F 151

Query: 138 NTLVTPWRLRLCIFLIWLYSTLVFLPS--FFHWGKPGYHG---------DVFQWCAESWH 186
              +T     + I +IW+ +  +  PS    H  +  Y+              WC E W 
Sbjct: 152 KPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWP 211

Query: 187 TDS----YFTLFIVMMLYAPAALIVCF---TYFNIFRICQQHTKDISERQARFSSQSGET 239
                  Y T+    +  AP +LIV        ++FR    HT   ++ Q    S+  + 
Sbjct: 212 NQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQ- 270

Query: 240 GEVQACPDKRYAMVLFRITSVFYILWLPYIIYFLLESSTGHS-------NRFASFLTTWL 292
                    +   +L  +  +F + WLP     +L      S       N +      WL
Sbjct: 271 ---------KIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIYIYPFAHWL 321

Query: 293 AISNSFCNCVIYSLSNSVFQRGLKRLSGAMCTSCASQTTANDPYTVRSK 341
           A  NS  N +IY   N  F+RG +         C  +    + Y +++K
Sbjct: 322 AFGNSSVNPIIYGFFNENFRRGFQ--EAFQLQLCQKRAKPMEAYALKAK 368


>gi|221316654 neuropeptide FF receptor 2 isoform 1 [Homo sapiens]
          Length = 522

 Score = 77.8 bits (190), Expect = 1e-14
 Identities = 78/349 (22%), Positives = 139/349 (39%), Gaps = 46/349 (13%)

Query: 21  YLETVNFCLLEVLIIVFLTVLIISGNIIVIFVFHCAPLLNHHTTSYFIQTMAYADLFVGV 80
           YL       + ++    +  L + GN +V F+      + H  T+ FI  +A +DL VG+
Sbjct: 140 YLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHM-HTVTNLFILNLAISDLLVGI 198

Query: 81  SCVVPSLSLLHHPL---PVEESLTCQIFGFVVSVLKSVSMASLACISIDRYIAITKPLTY 137
            C+   ++LL + +   P   ++ C+I G V  +  + S+ +L  I++DR+  +  P  +
Sbjct: 199 FCM--PITLLDNIIAGWPFGNTM-CKISGLVQGISVAASVFTLVAIAVDRFQCVVYP--F 253

Query: 138 NTLVTPWRLRLCIFLIWLYSTLVFLPS--FFHWGKPGYHG---------DVFQWCAESWH 186
              +T     + I +IW+ +  +  PS    H  +  Y+              WC E W 
Sbjct: 254 KPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWP 313

Query: 187 TDS----YFTLFIVMMLYAPAALIVCF---TYFNIFRICQQHTKDISERQARFSSQSGET 239
                  Y T+    +  AP +LIV        ++FR    HT   ++ Q    S+  + 
Sbjct: 314 NQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQ- 372

Query: 240 GEVQACPDKRYAMVLFRITSVFYILWLPYIIYFLLESSTGHS-------NRFASFLTTWL 292
                    +   +L  +  +F + WLP     +L      S       N +      WL
Sbjct: 373 ---------KIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIYIYPFAHWL 423

Query: 293 AISNSFCNCVIYSLSNSVFQRGLKRLSGAMCTSCASQTTANDPYTVRSK 341
           A  NS  N +IY   N  F+RG +         C  +    + Y +++K
Sbjct: 424 AFGNSSVNPIIYGFFNENFRRGFQ--EAFQLQLCQKRAKPMEAYALKAK 470


>gi|221316652 neuropeptide FF receptor 2 isoform 3 [Homo sapiens]
          Length = 423

 Score = 77.8 bits (190), Expect = 1e-14
 Identities = 78/349 (22%), Positives = 139/349 (39%), Gaps = 46/349 (13%)

Query: 21  YLETVNFCLLEVLIIVFLTVLIISGNIIVIFVFHCAPLLNHHTTSYFIQTMAYADLFVGV 80
           YL       + ++    +  L + GN +V F+      + H  T+ FI  +A +DL VG+
Sbjct: 41  YLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHM-HTVTNLFILNLAISDLLVGI 99

Query: 81  SCVVPSLSLLHHPL---PVEESLTCQIFGFVVSVLKSVSMASLACISIDRYIAITKPLTY 137
            C+   ++LL + +   P   ++ C+I G V  +  + S+ +L  I++DR+  +  P  +
Sbjct: 100 FCM--PITLLDNIIAGWPFGNTM-CKISGLVQGISVAASVFTLVAIAVDRFQCVVYP--F 154

Query: 138 NTLVTPWRLRLCIFLIWLYSTLVFLPS--FFHWGKPGYHG---------DVFQWCAESWH 186
              +T     + I +IW+ +  +  PS    H  +  Y+              WC E W 
Sbjct: 155 KPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWP 214

Query: 187 TDS----YFTLFIVMMLYAPAALIVCF---TYFNIFRICQQHTKDISERQARFSSQSGET 239
                  Y T+    +  AP +LIV        ++FR    HT   ++ Q    S+  + 
Sbjct: 215 NQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQ- 273

Query: 240 GEVQACPDKRYAMVLFRITSVFYILWLPYIIYFLLESSTGHS-------NRFASFLTTWL 292
                    +   +L  +  +F + WLP     +L      S       N +      WL
Sbjct: 274 ---------KIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIYIYPFAHWL 324

Query: 293 AISNSFCNCVIYSLSNSVFQRGLKRLSGAMCTSCASQTTANDPYTVRSK 341
           A  NS  N +IY   N  F+RG +         C  +    + Y +++K
Sbjct: 325 AFGNSSVNPIIYGFFNENFRRGFQ--EAFQLQLCQKRAKPMEAYALKAK 371


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.330    0.140    0.457 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,403,388
Number of Sequences: 37866
Number of extensions: 493106
Number of successful extensions: 2531
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 423
Number of HSP's successfully gapped in prelim test: 281
Number of HSP's that attempted gapping in prelim test: 1569
Number of HSP's gapped (non-prelim): 908
length of query: 349
length of database: 18,247,518
effective HSP length: 103
effective length of query: 246
effective length of database: 14,347,320
effective search space: 3529440720
effective search space used: 3529440720
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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