Guide to the Human Genome
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Search of human proteins with 4885179

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4885179 defensin, alpha 3 preproprotein [Homo sapiens]
         (94 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4885179 defensin, alpha 3 preproprotein [Homo sapiens]             195   7e-51
gi|4758146 defensin, alpha 1 preproprotein [Homo sapiens]             192   6e-50
gi|124248516 alpha-defensin 1 [Homo sapiens]                          192   6e-50
gi|4503303 defensin, alpha 4 preproprotein [Homo sapiens]              82   7e-17
gi|10337585 defensin, alpha 5 preproprotein [Homo sapiens]             81   2e-16
gi|4503305 defensin, alpha 6 preproprotein [Homo sapiens]              74   2e-14
gi|210032509 hypothetical protein LOC100130302 [Homo sapiens]          27   4.6  
gi|169202788 PREDICTED: hypothetical protein [Homo sapiens]            26   6.0  
gi|89034671 PREDICTED: hypothetical protein [Homo sapiens]             26   6.0  
gi|51470873 PREDICTED: hypothetical protein [Homo sapiens]             26   6.0  
gi|145580617 fucosyltransferase 11 (alpha (1,3) fucosyltransfera...    26   6.0  
gi|29294649 dicer1 [Homo sapiens]                                      26   7.9  
gi|29294651 dicer1 [Homo sapiens]                                      26   7.9  
gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo sap...    26   7.9  
gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo sapi...    26   7.9  
gi|38201692 RAS p21 protein activator 3 [Homo sapiens]                 26   7.9  

>gi|4885179 defensin, alpha 3 preproprotein [Homo sapiens]
          Length = 94

 Score =  195 bits (495), Expect = 7e-51
 Identities = 94/94 (100%), Positives = 94/94 (100%)

Query: 1  MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGS 60
          MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGS
Sbjct: 1  MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGS 60

Query: 61 RKNMDCYCRIPACIAGERRYGTCIYQGRLWAFCC 94
          RKNMDCYCRIPACIAGERRYGTCIYQGRLWAFCC
Sbjct: 61 RKNMDCYCRIPACIAGERRYGTCIYQGRLWAFCC 94


>gi|4758146 defensin, alpha 1 preproprotein [Homo sapiens]
          Length = 94

 Score =  192 bits (487), Expect = 6e-50
 Identities = 93/94 (98%), Positives = 93/94 (98%)

Query: 1  MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGS 60
          MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGS
Sbjct: 1  MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGS 60

Query: 61 RKNMDCYCRIPACIAGERRYGTCIYQGRLWAFCC 94
          RKNM CYCRIPACIAGERRYGTCIYQGRLWAFCC
Sbjct: 61 RKNMACYCRIPACIAGERRYGTCIYQGRLWAFCC 94


>gi|124248516 alpha-defensin 1 [Homo sapiens]
          Length = 94

 Score =  192 bits (487), Expect = 6e-50
 Identities = 93/94 (98%), Positives = 93/94 (98%)

Query: 1  MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGS 60
          MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGS
Sbjct: 1  MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGS 60

Query: 61 RKNMDCYCRIPACIAGERRYGTCIYQGRLWAFCC 94
          RKNM CYCRIPACIAGERRYGTCIYQGRLWAFCC
Sbjct: 61 RKNMACYCRIPACIAGERRYGTCIYQGRLWAFCC 94


>gi|4503303 defensin, alpha 4 preproprotein [Homo sapiens]
          Length = 97

 Score = 82.4 bits (202), Expect = 7e-17
 Identities = 44/94 (46%), Positives = 58/94 (61%), Gaps = 1/94 (1%)

Query: 1  MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGS 60
          MR +A+LAAILLVALQ +A PLQAR DE A   EQ   +  ++ +S AWD+S A +  GS
Sbjct: 1  MRIIALLAAILLVALQVRAGPLQARGDE-APGQEQRGPEDQDISISFAWDKSSALQVSGS 59

Query: 61 RKNMDCYCRIPACIAGERRYGTCIYQGRLWAFCC 94
           + M C CR+  C   E R G C+  G  + +CC
Sbjct: 60 TRGMVCSCRLVFCRRTELRVGNCLIGGVSFTYCC 93


>gi|10337585 defensin, alpha 5 preproprotein [Homo sapiens]
          Length = 94

 Score = 81.3 bits (199), Expect = 2e-16
 Identities = 46/94 (48%), Positives = 55/94 (58%), Gaps = 1/94 (1%)

Query: 1  MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGS 60
          MRT+AILAAILLVALQAQAE LQ RADE A   +Q   D  ++ +S A +   A +  GS
Sbjct: 1  MRTIAILAAILLVALQAQAESLQERADE-ATTQKQSGEDNQDLAISFAGNGLSALRTSGS 59

Query: 61 RKNMDCYCRIPACIAGERRYGTCIYQGRLWAFCC 94
          +    CYCR   C   E   G C   GRL+  CC
Sbjct: 60 QARATCYCRTGRCATRESLSGVCEISGRLYRLCC 93


>gi|4503305 defensin, alpha 6 preproprotein [Homo sapiens]
          Length = 100

 Score = 74.3 bits (181), Expect = 2e-14
 Identities = 46/100 (46%), Positives = 57/100 (57%), Gaps = 7/100 (7%)

Query: 1  MRTLAILAAILLVALQAQAEPLQARADEVAA------APEQIAADIPEVVVSLAWDESLA 54
          MRTL IL A+LLVALQA+AEPLQA  D + A      A EQ  A+  +  VS A D S +
Sbjct: 1  MRTLTILTAVLLVALQAKAEPLQAEDDPLQAKAYEADAQEQRGANDQDFAVSFAEDASSS 60

Query: 55 PKHPGSRKNMDCYCRIPACIAGERRYGTCIYQGRLWAFCC 94
           +  GS +   C+CR  +C + E  YGTC   G    FCC
Sbjct: 61 LRALGSTRAFTCHCR-RSCYSTEYSYGTCTVMGINHRFCC 99


>gi|210032509 hypothetical protein LOC100130302 [Homo sapiens]
          Length = 887

 Score = 26.6 bits (57), Expect = 4.6
 Identities = 21/51 (41%), Positives = 22/51 (43%), Gaps = 4/51 (7%)

Query: 7   LAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKH 57
           LAA    AL A A P  A     AAAP    A  P V  + A   S AP H
Sbjct: 522 LAAAAAPALAAAAAPALA----AAAAPAPAPAAAPAVAAAPAAAASAAPSH 568


>gi|169202788 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 224

 Score = 26.2 bits (56), Expect = 6.0
 Identities = 15/56 (26%), Positives = 23/56 (41%), Gaps = 14/56 (25%)

Query: 39  DIPEVVVSLAW--------------DESLAPKHPGSRKNMDCYCRIPACIAGERRY 80
           + PEV+  L W              DE LA  HPG R  +     +P+ + G  ++
Sbjct: 86  EAPEVMFELLWAGLELDVMGQLHIQDEELASTHPGRRLRLLLQHHVPSDLEGTEQW 141


>gi|89034671 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 224

 Score = 26.2 bits (56), Expect = 6.0
 Identities = 15/56 (26%), Positives = 23/56 (41%), Gaps = 14/56 (25%)

Query: 39  DIPEVVVSLAW--------------DESLAPKHPGSRKNMDCYCRIPACIAGERRY 80
           + PEV+  L W              DE LA  HPG R  +     +P+ + G  ++
Sbjct: 86  EAPEVMFELLWAGLELDVMGQLHIQDEELASTHPGRRLRLLLQHHVPSDLEGTEQW 141


>gi|51470873 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 224

 Score = 26.2 bits (56), Expect = 6.0
 Identities = 15/56 (26%), Positives = 23/56 (41%), Gaps = 14/56 (25%)

Query: 39  DIPEVVVSLAW--------------DESLAPKHPGSRKNMDCYCRIPACIAGERRY 80
           + PEV+  L W              DE LA  HPG R  +     +P+ + G  ++
Sbjct: 86  EAPEVMFELLWAGLELDVMGQLHIQDEELASTHPGRRLRLLLQHHVPSDLEGTEQW 141


>gi|145580617 fucosyltransferase 11 (alpha (1,3) fucosyltransferase)
           [Homo sapiens]
          Length = 492

 Score = 26.2 bits (56), Expect = 6.0
 Identities = 15/43 (34%), Positives = 20/43 (46%), Gaps = 5/43 (11%)

Query: 37  AADIPEVVVSLAWDESLAPKHPGSRKNMDCYCRIPACIAGERR 79
           A D+P   V L W   L P  PG  + ++  C   AC+A   R
Sbjct: 72  AGDLP---VLLWWSPGLFPHFPGDSERIE--CARGACVASRNR 109


>gi|29294649 dicer1 [Homo sapiens]
          Length = 1922

 Score = 25.8 bits (55), Expect = 7.9
 Identities = 11/26 (42%), Positives = 15/26 (57%), Gaps = 1/26 (3%)

Query: 50  DESLAPKHPGSRKNMDCYCR-IPACI 74
           +E+  P  PGS K   CY + IP C+
Sbjct: 732 EETSVPGRPGSTKRRQCYPKAIPECL 757


>gi|29294651 dicer1 [Homo sapiens]
          Length = 1922

 Score = 25.8 bits (55), Expect = 7.9
 Identities = 11/26 (42%), Positives = 15/26 (57%), Gaps = 1/26 (3%)

Query: 50  DESLAPKHPGSRKNMDCYCR-IPACI 74
           +E+  P  PGS K   CY + IP C+
Sbjct: 732 EETSVPGRPGSTKRRQCYPKAIPECL 757


>gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo
           sapiens]
          Length = 986

 Score = 25.8 bits (55), Expect = 7.9
 Identities = 15/68 (22%), Positives = 30/68 (44%), Gaps = 6/68 (8%)

Query: 16  QAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGSRKNMDCYCRIPACIA 75
           +A  +PL      + +AP+ + + + E  + L W     P+  G R+++       +C +
Sbjct: 311 RADLDPLDMPCTTIPSAPQAVISSVNETSLMLEW---TPPRDSGGREDLVYNIICKSCGS 367

Query: 76  GERRYGTC 83
           G    G C
Sbjct: 368 GR---GAC 372


>gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo
           sapiens]
          Length = 987

 Score = 25.8 bits (55), Expect = 7.9
 Identities = 15/68 (22%), Positives = 30/68 (44%), Gaps = 6/68 (8%)

Query: 16  QAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGSRKNMDCYCRIPACIA 75
           +A  +PL      + +AP+ + + + E  + L W     P+  G R+++       +C +
Sbjct: 311 RADLDPLDMPCTTIPSAPQAVISSVNETSLMLEW---TPPRDSGGREDLVYNIICKSCGS 367

Query: 76  GERRYGTC 83
           G    G C
Sbjct: 368 GR---GAC 372


>gi|38201692 RAS p21 protein activator 3 [Homo sapiens]
          Length = 834

 Score = 25.8 bits (55), Expect = 7.9
 Identities = 8/16 (50%), Positives = 10/16 (62%)

Query: 55 PKHPGSRKNMDCYCRI 70
          P +PG  K  DCYC +
Sbjct: 25 PSYPGPSKMRDCYCTV 40


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.135    0.436 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,567,427
Number of Sequences: 37866
Number of extensions: 136129
Number of successful extensions: 433
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 422
Number of HSP's gapped (non-prelim): 16
length of query: 94
length of database: 18,247,518
effective HSP length: 65
effective length of query: 29
effective length of database: 15,786,228
effective search space: 457800612
effective search space used: 457800612
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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