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Search of human proteins with 48476342
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|48476342 solute carrier family 25, member 23 [Homo sapiens]
(468 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|48476342 solute carrier family 25, member 23 [Homo sapiens] 937 0.0
gi|239755174 PREDICTED: similar to solute carrier family 25, mem... 631 0.0
gi|56699403 solute carrier family 25, member 25 isoform b [Homo ... 631 0.0
gi|56699407 solute carrier family 25, member 25 isoform c [Homo ... 611 e-175
gi|239755176 PREDICTED: similar to solute carrier family 25, mem... 605 e-173
gi|56699401 solute carrier family 25, member 25 isoform a [Homo ... 605 e-173
gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo ... 600 e-172
gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo s... 594 e-170
gi|56699405 solute carrier family 25, member 25 isoform d [Homo ... 552 e-157
gi|149274607 solute carrier family 25, member 41 [Homo sapiens] 367 e-101
gi|60460887 solute carrier family 25, member 42 [Homo sapiens] 176 3e-44
gi|27544933 solute carrier family 25, member 16 [Homo sapiens] 172 6e-43
gi|21687151 mitochondrial solute carrier protein [Homo sapiens] 120 3e-27
gi|156071462 solute carrier family 25, member A6 [Homo sapiens] 119 5e-27
gi|13775208 solute carrier family 25 (mitochondrial carrier; ade... 116 4e-26
gi|156071459 solute carrier family 25, member 5 [Homo sapiens] 116 5e-26
gi|21314739 solute carrier family 25, member 32 [Homo sapiens] 115 8e-26
gi|55749577 solute carrier family 25 (mitochondrial carrier; ade... 115 1e-25
gi|186928856 solute carrier family 25, member 19 [Homo sapiens] 110 4e-24
gi|186928860 solute carrier family 25, member 19 [Homo sapiens] 110 4e-24
gi|186928858 solute carrier family 25, member 19 [Homo sapiens] 110 4e-24
gi|58197562 solute carrier family 25, member 30 [Homo sapiens] 109 5e-24
gi|157388989 solute carrier family 25, member 36 isoform a [Homo... 109 5e-24
gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Ho... 106 5e-23
gi|13259543 solute carrier family 25, member 14 isoform UCP5S [H... 106 5e-23
gi|157388991 solute carrier family 25, member 36 isoform b [Homo... 105 7e-23
gi|7706306 solute carrier family 25, member 39 isoform b [Homo s... 102 1e-21
gi|219555665 solute carrier family 25, member 39 isoform a [Homo... 102 1e-21
gi|14150082 mitochondrial carrier protein MGC4399 [Homo sapiens] 100 5e-21
gi|82775373 solute carrier family 25, member 37 [Homo sapiens] 99 6e-21
>gi|48476342 solute carrier family 25, member 23 [Homo sapiens]
Length = 468
Score = 937 bits (2421), Expect = 0.0
Identities = 468/468 (100%), Positives = 468/468 (100%)
Query: 1 MRGSPGDAERRQRWGRLFEELDSNKDGRVDVHELRQGLARLGGGNPDPGAQQGISSEGDA 60
MRGSPGDAERRQRWGRLFEELDSNKDGRVDVHELRQGLARLGGGNPDPGAQQGISSEGDA
Sbjct: 1 MRGSPGDAERRQRWGRLFEELDSNKDGRVDVHELRQGLARLGGGNPDPGAQQGISSEGDA 60
Query: 61 DPDGGLDLEEFSRYLQEREQRLLLMFHSLDRNQDGHIDVSEIQQSFRALGISISLEQAEK 120
DPDGGLDLEEFSRYLQEREQRLLLMFHSLDRNQDGHIDVSEIQQSFRALGISISLEQAEK
Sbjct: 61 DPDGGLDLEEFSRYLQEREQRLLLMFHSLDRNQDGHIDVSEIQQSFRALGISISLEQAEK 120
Query: 121 ILHSMDRDGTMTIDWQEWRDHFLLHSLENVEDVLYFWKHSTVLDIGECLTVPDEFSKQEK 180
ILHSMDRDGTMTIDWQEWRDHFLLHSLENVEDVLYFWKHSTVLDIGECLTVPDEFSKQEK
Sbjct: 121 ILHSMDRDGTMTIDWQEWRDHFLLHSLENVEDVLYFWKHSTVLDIGECLTVPDEFSKQEK 180
Query: 181 LTGMWWKQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLNILGGLRSMVLEGGIRS 240
LTGMWWKQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLNILGGLRSMVLEGGIRS
Sbjct: 181 LTGMWWKQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLNILGGLRSMVLEGGIRS 240
Query: 241 LWRGNGINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQERFVAGSLAGATAQTIIYPM 300
LWRGNGINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQERFVAGSLAGATAQTIIYPM
Sbjct: 241 LWRGNGINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQERFVAGSLAGATAQTIIYPM 300
Query: 301 EVLKTRLTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETLK 360
EVLKTRLTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETLK
Sbjct: 301 EVLKTRLTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETLK 360
Query: 361 NWWLQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASIEGGPQLSMLG 420
NWWLQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASIEGGPQLSMLG
Sbjct: 361 NWWLQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASIEGGPQLSMLG 420
Query: 421 LLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQALGVTSR 468
LLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQALGVTSR
Sbjct: 421 LLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQALGVTSR 468
>gi|239755174 PREDICTED: similar to solute carrier family 25, member
25 isoform 1 [Homo sapiens]
Length = 503
Score = 631 bits (1627), Expect = 0.0
Identities = 315/463 (68%), Positives = 369/463 (79%), Gaps = 1/463 (0%)
Query: 6 GDAERRQRWGRLFEELDSNKDGRVDVHELRQGLARLGGGNPDPGAQQGISSEGDADPDGG 65
G + R R RLF+ LD N+DG + V++L GL RLG + G Q I GD D DG
Sbjct: 42 GGPDHRLRLWRLFQTLDVNRDGGLCVNDLAVGLRRLGLHRTE-GELQKIVQAGDKDLDGQ 100
Query: 66 LDLEEFSRYLQEREQRLLLMFHSLDRNQDGHIDVSEIQQSFRALGISISLEQAEKILHSM 125
LD EEF YLQ+ E++L L+F SLD+ DG ID EI QS R LG+ IS +QAEKIL SM
Sbjct: 101 LDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSM 160
Query: 126 DRDGTMTIDWQEWRDHFLLHSLENVEDVLYFWKHSTVLDIGECLTVPDEFSKQEKLTGMW 185
D++GTMTIDW EWRD+ LLH +EN+ +++ +WKHST+ D+GE LTVPDEF+ +E+ TGMW
Sbjct: 161 DKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMW 220
Query: 186 WKQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLNILGGLRSMVLEGGIRSLWRGN 245
W+ LVAG AGAVSRT TAPLDRLKV MQVHAS++N + I+GG M+ EGG RSLWRGN
Sbjct: 221 WRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGN 280
Query: 246 GINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQERFVAGSLAGATAQTIIYPMEVLKT 305
GINVLKIAPESAIKFMAYEQIKR + QETL + ER VAGSLAGA AQ+ IYPMEVLKT
Sbjct: 281 GINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKT 340
Query: 306 RLTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETLKNWWLQ 365
R+ LR+TGQY G+LDCARRIL REG AFY+GY+PN+LGIIPYAGIDLAVYETLKN WLQ
Sbjct: 341 RMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQ 400
Query: 366 QYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASIEGGPQLSMLGLLRHI 425
Y+ +SADPG+ VLLACGT+SSTCGQ+ASYPLALVRTRMQAQASIEG P+++M L +HI
Sbjct: 401 HYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHI 460
Query: 426 LSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQALGVTSR 468
L EG GLYRG+APNFMKVIPAVSISYVVYEN+K LGV SR
Sbjct: 461 LRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 503
>gi|56699403 solute carrier family 25, member 25 isoform b [Homo
sapiens]
Length = 503
Score = 631 bits (1627), Expect = 0.0
Identities = 315/463 (68%), Positives = 369/463 (79%), Gaps = 1/463 (0%)
Query: 6 GDAERRQRWGRLFEELDSNKDGRVDVHELRQGLARLGGGNPDPGAQQGISSEGDADPDGG 65
G + R R RLF+ LD N+DG + V++L GL RLG + G Q I GD D DG
Sbjct: 42 GGPDHRLRLWRLFQTLDVNRDGGLCVNDLAVGLRRLGLHRTE-GELQKIVQAGDKDLDGQ 100
Query: 66 LDLEEFSRYLQEREQRLLLMFHSLDRNQDGHIDVSEIQQSFRALGISISLEQAEKILHSM 125
LD EEF YLQ+ E++L L+F SLD+ DG ID EI QS R LG+ IS +QAEKIL SM
Sbjct: 101 LDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSM 160
Query: 126 DRDGTMTIDWQEWRDHFLLHSLENVEDVLYFWKHSTVLDIGECLTVPDEFSKQEKLTGMW 185
D++GTMTIDW EWRD+ LLH +EN+ +++ +WKHST+ D+GE LTVPDEF+ +E+ TGMW
Sbjct: 161 DKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMW 220
Query: 186 WKQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLNILGGLRSMVLEGGIRSLWRGN 245
W+ LVAG AGAVSRT TAPLDRLKV MQVHAS++N + I+GG M+ EGG RSLWRGN
Sbjct: 221 WRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGN 280
Query: 246 GINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQERFVAGSLAGATAQTIIYPMEVLKT 305
GINVLKIAPESAIKFMAYEQIKR + QETL + ER VAGSLAGA AQ+ IYPMEVLKT
Sbjct: 281 GINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKT 340
Query: 306 RLTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETLKNWWLQ 365
R+ LR+TGQY G+LDCARRIL REG AFY+GY+PN+LGIIPYAGIDLAVYETLKN WLQ
Sbjct: 341 RMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQ 400
Query: 366 QYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASIEGGPQLSMLGLLRHI 425
Y+ +SADPG+ VLLACGT+SSTCGQ+ASYPLALVRTRMQAQASIEG P+++M L +HI
Sbjct: 401 HYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHI 460
Query: 426 LSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQALGVTSR 468
L EG GLYRG+APNFMKVIPAVSISYVVYEN+K LGV SR
Sbjct: 461 LRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 503
>gi|56699407 solute carrier family 25, member 25 isoform c [Homo
sapiens]
Length = 489
Score = 611 bits (1576), Expect = e-175
Identities = 309/468 (66%), Positives = 363/468 (77%), Gaps = 7/468 (1%)
Query: 1 MRGSPGDAERRQRWGRLFEELDSNKDGRVDVHELRQGLARLGGGNPDPGAQQGISSEGDA 60
+RG+P A R Q L +DGR + E R + + G P + I GD
Sbjct: 29 VRGTPAPAWRDQMASFL-----GKQDGRAEATEKRPTILLVVG--PAEQFPKKIVQAGDK 81
Query: 61 DPDGGLDLEEFSRYLQEREQRLLLMFHSLDRNQDGHIDVSEIQQSFRALGISISLEQAEK 120
D DG LD EEF YLQ+ E++L L+F SLD+ DG ID EI QS R LG+ IS +QAEK
Sbjct: 82 DLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEK 141
Query: 121 ILHSMDRDGTMTIDWQEWRDHFLLHSLENVEDVLYFWKHSTVLDIGECLTVPDEFSKQEK 180
IL SMD++GTMTIDW EWRD+ LLH +EN+ +++ +WKHST+ D+GE LTVPDEF+ +E+
Sbjct: 142 ILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEER 201
Query: 181 LTGMWWKQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLNILGGLRSMVLEGGIRS 240
TGMWW+ LVAG AGAVSRT TAPLDRLKV MQVHAS++N + I+GG M+ EGG RS
Sbjct: 202 QTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARS 261
Query: 241 LWRGNGINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQERFVAGSLAGATAQTIIYPM 300
LWRGNGINVLKIAPESAIKFMAYEQIKR + QETL + ER VAGSLAGA AQ+ IYPM
Sbjct: 262 LWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPM 321
Query: 301 EVLKTRLTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETLK 360
EVLKTR+ LR+TGQY G+LDCARRIL REG AFY+GY+PN+LGIIPYAGIDLAVYETLK
Sbjct: 322 EVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLK 381
Query: 361 NWWLQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASIEGGPQLSMLG 420
N WLQ Y+ +SADPG+ VLLACGT+SSTCGQ+ASYPLALVRTRMQAQASIEG P+++M
Sbjct: 382 NAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSS 441
Query: 421 LLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQALGVTSR 468
L +HIL EG GLYRG+APNFMKVIPAVSISYVVYEN+K LGV SR
Sbjct: 442 LFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 489
>gi|239755176 PREDICTED: similar to solute carrier family 25, member
25 isoform 2 [Homo sapiens]
Length = 469
Score = 605 bits (1560), Expect = e-173
Identities = 296/418 (70%), Positives = 344/418 (82%)
Query: 51 QQGISSEGDADPDGGLDLEEFSRYLQEREQRLLLMFHSLDRNQDGHIDVSEIQQSFRALG 110
+Q I GD D DG LD EEF YLQ+ E++L L+F SLD+ DG ID EI QS R LG
Sbjct: 52 KQKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLG 111
Query: 111 ISISLEQAEKILHSMDRDGTMTIDWQEWRDHFLLHSLENVEDVLYFWKHSTVLDIGECLT 170
+ IS +QAEKIL SMD++GTMTIDW EWRD+ LLH +EN+ +++ +WKHST+ D+GE LT
Sbjct: 112 VKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLT 171
Query: 171 VPDEFSKQEKLTGMWWKQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLNILGGLR 230
VPDEF+ +E+ TGMWW+ LVAG AGAVSRT TAPLDRLKV MQVHAS++N + I+GG
Sbjct: 172 VPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFT 231
Query: 231 SMVLEGGIRSLWRGNGINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQERFVAGSLAG 290
M+ EGG RSLWRGNGINVLKIAPESAIKFMAYEQIKR + QETL + ER VAGSLAG
Sbjct: 232 QMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAG 291
Query: 291 ATAQTIIYPMEVLKTRLTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAG 350
A AQ+ IYPMEVLKTR+ LR+TGQY G+LDCARRIL REG AFY+GY+PN+LGIIPYAG
Sbjct: 292 AIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 351
Query: 351 IDLAVYETLKNWWLQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASI 410
IDLAVYETLKN WLQ Y+ +SADPG+ VLLACGT+SSTCGQ+ASYPLALVRTRMQAQASI
Sbjct: 352 IDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASI 411
Query: 411 EGGPQLSMLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQALGVTSR 468
EG P+++M L +HIL EG GLYRG+APNFMKVIPAVSISYVVYEN+K LGV SR
Sbjct: 412 EGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 469
>gi|56699401 solute carrier family 25, member 25 isoform a [Homo
sapiens]
Length = 469
Score = 605 bits (1560), Expect = e-173
Identities = 296/418 (70%), Positives = 344/418 (82%)
Query: 51 QQGISSEGDADPDGGLDLEEFSRYLQEREQRLLLMFHSLDRNQDGHIDVSEIQQSFRALG 110
+Q I GD D DG LD EEF YLQ+ E++L L+F SLD+ DG ID EI QS R LG
Sbjct: 52 KQKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLG 111
Query: 111 ISISLEQAEKILHSMDRDGTMTIDWQEWRDHFLLHSLENVEDVLYFWKHSTVLDIGECLT 170
+ IS +QAEKIL SMD++GTMTIDW EWRD+ LLH +EN+ +++ +WKHST+ D+GE LT
Sbjct: 112 VKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLT 171
Query: 171 VPDEFSKQEKLTGMWWKQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLNILGGLR 230
VPDEF+ +E+ TGMWW+ LVAG AGAVSRT TAPLDRLKV MQVHAS++N + I+GG
Sbjct: 172 VPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFT 231
Query: 231 SMVLEGGIRSLWRGNGINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQERFVAGSLAG 290
M+ EGG RSLWRGNGINVLKIAPESAIKFMAYEQIKR + QETL + ER VAGSLAG
Sbjct: 232 QMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAG 291
Query: 291 ATAQTIIYPMEVLKTRLTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAG 350
A AQ+ IYPMEVLKTR+ LR+TGQY G+LDCARRIL REG AFY+GY+PN+LGIIPYAG
Sbjct: 292 AIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 351
Query: 351 IDLAVYETLKNWWLQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASI 410
IDLAVYETLKN WLQ Y+ +SADPG+ VLLACGT+SSTCGQ+ASYPLALVRTRMQAQASI
Sbjct: 352 IDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASI 411
Query: 411 EGGPQLSMLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQALGVTSR 468
EG P+++M L +HIL EG GLYRG+APNFMKVIPAVSISYVVYEN+K LGV SR
Sbjct: 412 EGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 469
>gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo
sapiens]
Length = 477
Score = 600 bits (1547), Expect = e-172
Identities = 285/462 (61%), Positives = 369/462 (79%), Gaps = 1/462 (0%)
Query: 7 DAERRQRWGRLFEELDSNKDGRVDVHELRQGLARLGGGNPDPGAQQGISSEGDADPDGGL 66
DAE+ R+ LF+ LD N DG VD+ EL++GL LG A++ I + GD + DG L
Sbjct: 17 DAEQPTRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQD-AEEKIFTTGDVNKDGKL 75
Query: 67 DLEEFSRYLQEREQRLLLMFHSLDRNQDGHIDVSEIQQSFRALGISISLEQAEKILHSMD 126
D EEF +YL++ E+++ L F SLD+N DG I+ SEI QS + LG++IS +QAE IL S+D
Sbjct: 76 DFEEFMKYLKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAELILQSID 135
Query: 127 RDGTMTIDWQEWRDHFLLHSLENVEDVLYFWKHSTVLDIGECLTVPDEFSKQEKLTGMWW 186
DGTMT+DW EWRD+FL + + ++E+++ FWKHST +DIG+ LT+PDEF++ EK +G WW
Sbjct: 136 VDGTMTVDWNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTIPDEFTEDEKKSGQWW 195
Query: 187 KQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLNILGGLRSMVLEGGIRSLWRGNG 246
+QL+AG +AGAVSRT TAPLDRLK+ MQVH SK++++NI GG R MV EGGIRSLWRGNG
Sbjct: 196 RQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNG 255
Query: 247 INVLKIAPESAIKFMAYEQIKRAILGQQETLHVQERFVAGSLAGATAQTIIYPMEVLKTR 306
NV+KIAPE+A+KF AYEQ K+ + + + + ERF++GS+AGATAQT IYPMEV+KTR
Sbjct: 256 TNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTR 315
Query: 307 LTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETLKNWWLQQ 366
L + +TGQY G+ DCA++IL+ EG AFY+GY+PN+LGIIPYAGIDLAVYE LK++WL
Sbjct: 316 LAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDN 375
Query: 367 YSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASIEGGPQLSMLGLLRHIL 426
++ DS +PG++VLL CG +SSTCGQ+ASYPLALVRTRMQAQA +EG PQL+M+GL R I+
Sbjct: 376 FAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRII 435
Query: 427 SQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQALGVTSR 468
S+EG+ GLYRGI PNFMKV+PAV ISYVVYENMKQ LGVT +
Sbjct: 436 SKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQTLGVTQK 477
>gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo
sapiens]
Length = 458
Score = 594 bits (1531), Expect = e-170
Identities = 281/455 (61%), Positives = 365/455 (80%), Gaps = 1/455 (0%)
Query: 14 WGRLFEELDSNKDGRVDVHELRQGLARLGGGNPDPGAQQGISSEGDADPDGGLDLEEFSR 73
+G LF LD NKDG +D+ EL++GL +G A++ I + GD + DG LD EEF +
Sbjct: 5 YGDLFWYLDYNKDGTLDIFELQEGLEDVGAIQSLEEAKK-IFTTGDVNKDGKLDFEEFMK 63
Query: 74 YLQEREQRLLLMFHSLDRNQDGHIDVSEIQQSFRALGISISLEQAEKILHSMDRDGTMTI 133
YL++ E+++ L F SLD+N DG I+ SEI QS + LG++IS +QAE IL S+D DGTMT+
Sbjct: 64 YLKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAELILQSIDVDGTMTV 123
Query: 134 DWQEWRDHFLLHSLENVEDVLYFWKHSTVLDIGECLTVPDEFSKQEKLTGMWWKQLVAGA 193
DW EWRD+FL + + ++E+++ FWKHST +DIG+ LT+PDEF++ EK +G WW+QL+AG
Sbjct: 124 DWNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTIPDEFTEDEKKSGQWWRQLLAGG 183
Query: 194 VAGAVSRTGTAPLDRLKVFMQVHASKTNRLNILGGLRSMVLEGGIRSLWRGNGINVLKIA 253
+AGAVSRT TAPLDRLK+ MQVH SK++++NI GG R MV EGGIRSLWRGNG NV+KIA
Sbjct: 184 IAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTNVIKIA 243
Query: 254 PESAIKFMAYEQIKRAILGQQETLHVQERFVAGSLAGATAQTIIYPMEVLKTRLTLRRTG 313
PE+A+KF AYEQ K+ + + + + ERF++GS+AGATAQT IYPMEV+KTRL + +TG
Sbjct: 244 PETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTRLAVGKTG 303
Query: 314 QYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETLKNWWLQQYSHDSAD 373
QY G+ DCA++IL+ EG AFY+GY+PN+LGIIPYAGIDLAVYE LK++WL ++ DS +
Sbjct: 304 QYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVN 363
Query: 374 PGILVLLACGTISSTCGQIASYPLALVRTRMQAQASIEGGPQLSMLGLLRHILSQEGMRG 433
PG++VLL CG +SSTCGQ+ASYPLALVRTRMQAQA +EG PQL+M+GL R I+S+EG+ G
Sbjct: 364 PGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPG 423
Query: 434 LYRGIAPNFMKVIPAVSISYVVYENMKQALGVTSR 468
LYRGI PNFMKV+PAV ISYVVYENMKQ LGVT +
Sbjct: 424 LYRGITPNFMKVLPAVGISYVVYENMKQTLGVTQK 458
>gi|56699405 solute carrier family 25, member 25 isoform d [Homo
sapiens]
Length = 366
Score = 552 bits (1422), Expect = e-157
Identities = 268/365 (73%), Positives = 310/365 (84%)
Query: 104 QSFRALGISISLEQAEKILHSMDRDGTMTIDWQEWRDHFLLHSLENVEDVLYFWKHSTVL 163
QS R LG+ IS +QAEKIL SMD++GTMTIDW EWRD+ LLH +EN+ +++ +WKHST+
Sbjct: 2 QSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIF 61
Query: 164 DIGECLTVPDEFSKQEKLTGMWWKQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRL 223
D+GE LTVPDEF+ +E+ TGMWW+ LVAG AGAVSRT TAPLDRLKV MQVHAS++N +
Sbjct: 62 DVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNM 121
Query: 224 NILGGLRSMVLEGGIRSLWRGNGINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQERF 283
I+GG M+ EGG RSLWRGNGINVLKIAPESAIKFMAYEQIKR + QETL + ER
Sbjct: 122 GIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERL 181
Query: 284 VAGSLAGATAQTIIYPMEVLKTRLTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVL 343
VAGSLAGA AQ+ IYPMEVLKTR+ LR+TGQY G+LDCARRIL REG AFY+GY+PN+L
Sbjct: 182 VAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNML 241
Query: 344 GIIPYAGIDLAVYETLKNWWLQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTR 403
GIIPYAGIDLAVYETLKN WLQ Y+ +SADPG+ VLLACGT+SSTCGQ+ASYPLALVRTR
Sbjct: 242 GIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTR 301
Query: 404 MQAQASIEGGPQLSMLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQAL 463
MQAQASIEG P+++M L +HIL EG GLYRG+APNFMKVIPAVSISYVVYEN+K L
Sbjct: 302 MQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITL 361
Query: 464 GVTSR 468
GV SR
Sbjct: 362 GVQSR 366
>gi|149274607 solute carrier family 25, member 41 [Homo sapiens]
Length = 370
Score = 367 bits (942), Expect = e-101
Identities = 196/304 (64%), Positives = 235/304 (77%), Gaps = 3/304 (0%)
Query: 162 VLDIGECLTVPDEFSKQEKLTGMWWKQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTN 221
VLD GE L VP E + + +W K L++GA+AGAVSRTGTAPLDR KV+MQV++SKTN
Sbjct: 70 VLDTGEQLMVPVEVLEVDNKEALW-KFLLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTN 128
Query: 222 RLNILGGLRSMVLEGGIRSLWRGNGINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQE 281
N+LGGL+SMV EGG RSLWRGNGINVLKIAPE AIKF +EQ K G Q + QE
Sbjct: 129 FTNLLGGLQSMVQEGGFRSLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCGIQGSPPFQE 188
Query: 282 RFVAGSLAGATAQTIIYPMEVLKTRLTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPN 341
R +AGSLA A +QT+I PMEVLKTRLTLRRTGQYKGLLDCAR+IL+REG RA YRGYLPN
Sbjct: 189 RLLAGSLAVAISQTLINPMEVLKTRLTLRRTGQYKGLLDCARQILQREGTRALYRGYLPN 248
Query: 342 VLGIIPYAGIDLAVYETLKNWWLQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVR 401
+LGIIPYA DLAVYE L+ +W++ D DP LV L+ T+S+TCGQ+ASYPL LVR
Sbjct: 249 MLGIIPYACTDLAVYEMLQCFWVKS-GRDMGDPSGLVSLSSVTLSTTCGQMASYPLTLVR 307
Query: 402 TRMQAQASIEGGPQLSMLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQ 461
TRMQAQ ++EG +M G+L+ IL+Q+G GLYRG+ P +KV+PA ISYVVYE MK+
Sbjct: 308 TRMQAQDTVEGS-NPTMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKK 366
Query: 462 ALGV 465
LG+
Sbjct: 367 TLGI 370
>gi|60460887 solute carrier family 25, member 42 [Homo sapiens]
Length = 318
Score = 176 bits (447), Expect = 3e-44
Identities = 105/278 (37%), Positives = 158/278 (56%), Gaps = 10/278 (3%)
Query: 189 LVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLNILGGLRSMVLEGGIRSLWRGNGIN 248
L+ GA+AGA+++T APLDR K+ QV + + + L L G SLWRGN
Sbjct: 37 LLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYLNEGFLSLWRGNSAT 96
Query: 249 VLKIAPESAIKFMAYEQIKRAILGQQ-----ETLHVQERFVAGSLAGATAQTIIYPMEVL 303
++++ P +AI+F A+E+ KR ILG E L R AG+LAG TA ++ YP++++
Sbjct: 97 MVRVVPYAAIQFSAHEEYKR-ILGSYYGFRGEALPPWPRLFAGALAGTTAASLTYPLDLV 155
Query: 304 KTRLTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETLKNWW 363
+ R+ + Y + RI EG + Y G++P VLG+IPYAG+ YETLK+
Sbjct: 156 RARMAVTPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTYETLKS-- 213
Query: 364 LQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASIEGGPQLSMLGLLR 423
L + P + G + GQ ASYPL +VR RMQ A + G P+ S+ LR
Sbjct: 214 LHREYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVRRRMQT-AGVTGYPRASIARTLR 272
Query: 424 HILSQEG-MRGLYRGIAPNFMKVIPAVSISYVVYENMK 460
I+ +EG +RGLY+G++ N++K AV IS+ ++ M+
Sbjct: 273 TIVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFDLMQ 310
Score = 65.9 bits (159), Expect = 8e-11
Identities = 48/198 (24%), Positives = 89/198 (44%), Gaps = 8/198 (4%)
Query: 266 IKRAILGQQETLHVQERFVAGSLAGATAQTIIYPMEVLKTRLTLRRTGQYKGLLDCARRI 325
+ ++ +++ V + G+LAGA A+T + P++ +T++ + + + + R +
Sbjct: 20 LSSSVSSKRDHRQVLSSLLPGALAGALAKTAVAPLD--RTKIIFQVSSKRFSAKEAFRVL 77
Query: 326 LE---REGPRAFYRGYLPNVLGIIPYAGIDLAVYETLKNWWLQQYSHDSADPGILVLLAC 382
EG + +RG ++ ++PYA I + +E K Y L
Sbjct: 78 YYTYLNEGFLSLWRGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFA 137
Query: 383 GTISSTCGQIASYPLALVRTRMQAQASIEGGPQLSMLGLLRHILSQEGMRGLYRGIAPNF 442
G ++ T +YPL LVR RM A ++ + I +EG++ LY G P
Sbjct: 138 GALAGTTAASLTYPLDLVRARM---AVTPKEMYSNIFHVFIRISREEGLKTLYHGFMPTV 194
Query: 443 MKVIPAVSISYVVYENMK 460
+ VIP +S+ YE +K
Sbjct: 195 LGVIPYAGLSFFTYETLK 212
Score = 63.2 bits (152), Expect = 5e-10
Identities = 51/181 (28%), Positives = 87/181 (48%), Gaps = 8/181 (4%)
Query: 186 WKQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLNILGGLRSMVLEGGIRSLWRGN 245
W +L AGA+AG + + T PLD ++ M V K NI + E G+++L+ G
Sbjct: 132 WPRLFAGALAGTTAASLTYPLDLVRARMAV-TPKEMYSNIFHVFIRISREEGLKTLYHGF 190
Query: 246 GINVLKIAPESAIKFMAYEQIK---RAILGQQETLHVQERFVAGSLAGATAQTIIYPMEV 302
VL + P + + F YE +K R G+++ + ER + G+ AG Q+ YP++V
Sbjct: 191 MPTVLGVIPYAGLSFFTYETLKSLHREYSGRRQP-YPFERMIFGACAGLIGQSASYPLDV 249
Query: 303 LKTRL-TLRRTGQYKGLLDCARRILERE--GPRAFYRGYLPNVLGIIPYAGIDLAVYETL 359
++ R+ T TG + + R + RE R Y+G N + GI ++ +
Sbjct: 250 VRRRMQTAGVTGYPRASIARTLRTIVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFDLM 309
Query: 360 K 360
+
Sbjct: 310 Q 310
Score = 34.3 bits (77), Expect = 0.25
Identities = 23/89 (25%), Positives = 41/89 (46%), Gaps = 2/89 (2%)
Query: 376 ILVLLACGTISSTCGQIASYPLALVRTRMQAQASIEGGPQLSMLGLLRHILSQEGMRGLY 435
+L L G ++ + A PL RT++ Q S + +L + EG L+
Sbjct: 33 VLSSLLPGALAGALAKTAVAPLD--RTKIIFQVSSKRFSAKEAFRVLYYTYLNEGFLSLW 90
Query: 436 RGIAPNFMKVIPAVSISYVVYENMKQALG 464
RG + ++V+P +I + +E K+ LG
Sbjct: 91 RGNSATMVRVVPYAAIQFSAHEEYKRILG 119
>gi|27544933 solute carrier family 25, member 16 [Homo sapiens]
Length = 332
Score = 172 bits (436), Expect = 6e-43
Identities = 100/292 (34%), Positives = 160/292 (54%), Gaps = 15/292 (5%)
Query: 185 WWKQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLNILGGLRSMVLEGGIRSLWRG 244
W + +AG +AG ++T APLDR+KV +Q H L + LR++ + G L++G
Sbjct: 36 WLRSFLAGGIAGCCAKTTVAPLDRVKVLLQAHNHHYKHLGVFSALRAVPQKEGFLGLYKG 95
Query: 245 NGINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQERFVAGSLAGATAQTIIYPMEVLK 304
NG +++I P AI+FMA+E K I + R +AGS+AG TA YP+++++
Sbjct: 96 NGAMMIRIFPYGAIQFMAFEHYKTLITTKLGISGHVHRLMAGSMAGMTAVICTYPLDMVR 155
Query: 305 TRLTLRRTGQ--YKGLLDCARRILEREGP-RAFYRGYLPNVLGIIPYAGIDLAVYETLKN 361
RL + G+ Y G++ + I +EG FYRG +P +LG+ PYAG+ + TLK+
Sbjct: 156 VRLAFQVKGEHSYTGIIHAFKTIYAKEGGFFGFYRGLMPTILGMAPYAGVSFFTFGTLKS 215
Query: 362 WWLQQY-----SHDSADPGILVL-----LACGTISSTCGQIASYPLALVRTRMQAQASI- 410
L S +P +LVL L CG ++ Q SYP + R RMQ +
Sbjct: 216 VGLSHAPTLLGRPSSDNPNVLVLKTHVNLLCGGVAGAIAQTISYPFDVTRRRMQLGTVLP 275
Query: 411 EGGPQLSMLGLLRHILSQEGMR-GLYRGIAPNFMKVIPAVSISYVVYENMKQ 461
E L+M ++++ G+R GLYRG++ N+++ IP+ ++++ YE MKQ
Sbjct: 276 EFEKCLTMRDTMKYVYGHHGIRKGLYRGLSLNYIRCIPSQAVAFTTYELMKQ 327
Score = 58.2 bits (139), Expect = 2e-08
Identities = 52/199 (26%), Positives = 88/199 (44%), Gaps = 25/199 (12%)
Query: 188 QLVAGAVAGAVSRTGTAPLDRLKVFMQVHAS-KTNRLNILGGLRSMVL-EGGIRSLWRGN 245
+L+AG++AG + T PLD ++V + + + I+ +++ EGG +RG
Sbjct: 133 RLMAGSMAGMTAVICTYPLDMVRVRLAFQVKGEHSYTGIIHAFKTIYAKEGGFFGFYRGL 192
Query: 246 GINVLKIAPESAIKFMAYEQIKRAILGQQETL----------------HVQERFVAGSLA 289
+L +AP + + F + +K L TL HV + G +A
Sbjct: 193 MPTILGMAPYAGVSFFTFGTLKSVGLSHAPTLLGRPSSDNPNVLVLKTHVN--LLCGGVA 250
Query: 290 GATAQTIIYPMEVLKTRLTLRRT-GQYKGLL---DCARRILEREGPR-AFYRGYLPNVLG 344
GA AQTI YP +V + R+ L +++ L D + + G R YRG N +
Sbjct: 251 GAIAQTISYPFDVTRRRMQLGTVLPEFEKCLTMRDTMKYVYGHHGIRKGLYRGLSLNYIR 310
Query: 345 IIPYAGIDLAVYETLKNWW 363
IP + YE +K ++
Sbjct: 311 CIPSQAVAFTTYELMKQFF 329
>gi|21687151 mitochondrial solute carrier protein [Homo sapiens]
Length = 341
Score = 120 bits (301), Expect = 3e-27
Identities = 84/292 (28%), Positives = 143/292 (48%), Gaps = 18/292 (6%)
Query: 180 KLTGMWWKQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLNILGGLRSMVLEGGIR 239
+LTG ++L+ +AG +S + TAPL+ V QV + + + G+R
Sbjct: 9 RLTG--GQRLLCAGLAGTLSLSLTAPLELATVLAQVGVVRGHARGPWATGHRVWRAEGLR 66
Query: 240 SLWRGNGINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQE--RFVAGSLAGATAQTII 297
+LW+GN + L++ P SA++ AY K +L + H+ + +AGSLAG + +
Sbjct: 67 ALWKGNAVACLRLFPCSAVQLAAYR--KFVVLFTDDLGHISQWSSIMAGSLAGMVSTIVT 124
Query: 298 YPMEVLKTRLTLRR--TGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAV 355
YP +++KTRL ++ Y+GLL I ++EG A YRG V+G +P++ L V
Sbjct: 125 YPTDLIKTRLIMQNILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAGSLLV 184
Query: 356 YETLKNWWLQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASI---EG 412
Y L+ W S + ++ T S+P V+ +MQAQ+ G
Sbjct: 185 YMNLEKIWNGPRDQFSLPQNFANVCLAAAVTQT----LSFPFETVKRKMQAQSPYLPHSG 240
Query: 413 GPQLSMLGLL---RHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQ 461
G + G + R I+ +G+ GL+ G+ N +K++P I + +E K+
Sbjct: 241 GVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCKR 292
Score = 81.3 bits (199), Expect = 2e-15
Identities = 51/191 (26%), Positives = 93/191 (48%), Gaps = 10/191 (5%)
Query: 186 WKQLVAGAVAGAVSRTGTAPLDRLKV-FMQVHASKTNRLNILGGLRSMVLEGGIRSLWRG 244
W ++AG++AG VS T P D +K + + + + +L ++ + G +L+RG
Sbjct: 107 WSSIMAGSLAGMVSTIVTYPTDLIKTRLIMQNILEPSYRGLLHAFSTIYQQEGFLALYRG 166
Query: 245 NGINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQERFVAGSLAGATAQTIIYPMEVLK 304
+ V+ P SA + Y +++ G ++ + + F LA A QT+ +P E +K
Sbjct: 167 VSLTVVGALPFSAGSLLVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVK 226
Query: 305 TRLT-----LRRTG----QYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAV 355
++ L +G + G +DC R+I++ +G + G N+L I+PY GI +
Sbjct: 227 RKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFST 286
Query: 356 YETLKNWWLQQ 366
+E K L Q
Sbjct: 287 FEFCKRICLYQ 297
>gi|156071462 solute carrier family 25, member A6 [Homo sapiens]
Length = 298
Score = 119 bits (299), Expect = 5e-27
Identities = 88/296 (29%), Positives = 151/296 (51%), Gaps = 26/296 (8%)
Query: 187 KQLVAGAVAGAVSRTGTAPLDRLKVFMQV-HASK-----TNRLNILGGLRSMVLEGGIRS 240
K +AG +A A+S+T AP++R+K+ +QV HASK I+ + + E G+ S
Sbjct: 10 KDFLAGGIAAAISKTAVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVRIPKEQGVLS 69
Query: 241 LWRGNGINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQERFVAGSL-----AGATAQT 295
WRGN NV++ P A+ F ++ K+ LG + R+ AG+L AGAT+
Sbjct: 70 FWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKHTQFWRYFAGNLASGGAAGATSLC 129
Query: 296 IIYPMEVLKTRLT--LRRTG---QYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAG 350
+YP++ +TRL + ++G +++GL DC +I + +G R Y+G+ +V GII Y
Sbjct: 130 FVYPLDFARTRLAADVGKSGTEREFRGLGDCLVKITKSDGIRGLYQGFSVSVQGIIIYRA 189
Query: 351 IDLAVYETLKNWWLQQYSHDSADPGILV-LLACGTISSTCGQIASYPLALVRTRMQAQAS 409
VY+T K D + I+V + T+++ G + SYP VR RM Q+
Sbjct: 190 AYFGVYDTAKG-----MLPDPKNTHIVVSWMIAQTVTAVAG-VVSYPFDTVRRRMMMQSG 243
Query: 410 IEGGPQL--SMLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQAL 463
+G + + R I EG + ++G N ++ + + V+Y+ +K+ +
Sbjct: 244 RKGADIMYTGTVDCWRKIFRDEGGKAFFKGAWSNVLRGMGGAFV-LVLYDELKKVI 298
Score = 73.9 bits (180), Expect = 3e-13
Identities = 56/201 (27%), Positives = 93/201 (46%), Gaps = 12/201 (5%)
Query: 274 QETLHVQERFVAGSLAGATAQTIIYPMEVLKTRLTLRRTG-------QYKGLLDCARRIL 326
++ + + F+AG +A A ++T + P+E +K L ++ QYKG++DC RI
Sbjct: 3 EQAISFAKDFLAGGIAAAISKTAVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVRIP 62
Query: 327 EREGPRAFYRGYLPNVLGIIPYAGIDLAVYETLKNWWLQQY-SHDSADPGILVLLACGTI 385
+ +G +F+RG L NV+ P ++ A + K +L H LA G
Sbjct: 63 KEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKHTQFWRYFAGNLASGGA 122
Query: 386 SSTCGQIASYPLALVRTRMQAQASIEGGPQLSMLGL---LRHILSQEGMRGLYRGIAPNF 442
+ YPL RTR+ A + G + GL L I +G+RGLY+G + +
Sbjct: 123 AGATSLCFVYPLDFARTRLAADVG-KSGTEREFRGLGDCLVKITKSDGIRGLYQGFSVSV 181
Query: 443 MKVIPAVSISYVVYENMKQAL 463
+I + + VY+ K L
Sbjct: 182 QGIIIYRAAYFGVYDTAKGML 202
>gi|13775208 solute carrier family 25 (mitochondrial carrier;
adenine nucleotide translocator), member 31 [Homo
sapiens]
Length = 315
Score = 116 bits (291), Expect = 4e-26
Identities = 86/291 (29%), Positives = 135/291 (46%), Gaps = 22/291 (7%)
Query: 187 KQLVAGAVAGAVSRTGTAPLDRLKVFMQVHAS------KTNRLNILGGLRSMVLEGGIRS 240
K L+AG VA AVS+T AP++R+K+ +QV AS + ++ L + E G S
Sbjct: 22 KDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFS 81
Query: 241 LWRGNGINVLKIAPESAIKFMAYEQIKRAIL-GQQETLHVQERFVA----GSLAGATAQT 295
WRGN NV++ P A+ F ++ K+ + G + F+A G AGAT+
Sbjct: 82 FWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLC 141
Query: 296 IIYPMEVLKTRLTL-----RRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAG 350
++YP++ +TRL + Q+KGL DC +I + +G Y+G+ +V GII Y
Sbjct: 142 VVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYRA 201
Query: 351 IDLAVYETLKNWWLQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASI 410
Y+T+K LV + +TC I SYP VR RM Q+
Sbjct: 202 SYFGAYDTVKG-----LLPKPKKTPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQSGE 256
Query: 411 EGGPQLSMLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQ 461
L I EG+ +RG N ++ ++ V+Y+ +K+
Sbjct: 257 AKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLRGTGG-ALVLVLYDKIKE 306
Score = 65.9 bits (159), Expect = 8e-11
Identities = 54/194 (27%), Positives = 92/194 (47%), Gaps = 10/194 (5%)
Query: 178 QEKLTGMWW-KQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLNILGGLRSMVLE- 235
+EK W+ L +G AGA S PLD + + V K GL +++
Sbjct: 117 KEKQFWRWFLANLASGGAAGATSLCVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKI 176
Query: 236 ---GGIRSLWRGNGINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQERFVAGSLAGAT 292
GI L++G G++V I A F AY+ +K + ++T + F+A +
Sbjct: 177 AKSDGIAGLYQGFGVSVQGIIVYRASYFGAYDTVKGLLPKPKKTPFLVSFFIA-QVVTTC 235
Query: 293 AQTIIYPMEVLKTRLTLR---RTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYA 349
+ + YP + ++ R+ ++ QYKG LDC +I + EG +F+RG NVL A
Sbjct: 236 SGILSYPFDTVRRRMMMQSGEAKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLRGTGGA 295
Query: 350 GIDLAVYETLKNWW 363
+ L +Y+ +K ++
Sbjct: 296 -LVLVLYDKIKEFF 308
>gi|156071459 solute carrier family 25, member 5 [Homo sapiens]
Length = 298
Score = 116 bits (290), Expect = 5e-26
Identities = 86/294 (29%), Positives = 147/294 (50%), Gaps = 26/294 (8%)
Query: 187 KQLVAGAVAGAVSRTGTAPLDRLKVFMQV-HASK-----TNRLNILGGLRSMVLEGGIRS 240
K +AG VA A+S+T AP++R+K+ +QV HASK I+ + + E G+ S
Sbjct: 10 KDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLS 69
Query: 241 LWRGNGINVLKIAPESAIKFMAYEQIKRAILG-----QQETLHVQERFVAGSLAGATAQT 295
WRGN NV++ P A+ F ++ K+ LG Q L+ +G AGAT+
Sbjct: 70 FWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSLC 129
Query: 296 IIYPMEVLKTRLT--LRRTG---QYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAG 350
+YP++ +TRL + + G +++GL DC +I + +G + Y+G+ +V GII Y
Sbjct: 130 FVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRA 189
Query: 351 IDLAVYETLKNWWLQQYSHDSADPGILV-LLACGTISSTCGQIASYPLALVRTRMQAQAS 409
+Y+T K D + I++ + T+++ G + SYP VR RM Q+
Sbjct: 190 AYFGIYDTAKG-----MLPDPKNTHIVISWMIAQTVTAVAG-LTSYPFDTVRRRMMMQSG 243
Query: 410 IEGGPQL--SMLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQ 461
+G + L R I EG + ++G N ++ + + V+Y+ +K+
Sbjct: 244 RKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGGAFV-LVLYDEIKK 296
Score = 69.3 bits (168), Expect = 7e-12
Identities = 54/198 (27%), Positives = 92/198 (46%), Gaps = 24/198 (12%)
Query: 283 FVAGSLAGATAQTIIYPMEVLKTRLTLRRTG-------QYKGLLDCARRILEREGPRAFY 335
F+AG +A A ++T + P+E +K L ++ QYKG++DC RI + +G +F+
Sbjct: 12 FLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSFW 71
Query: 336 RGYLPNVLGIIPYAGIDLAVYETLKNWWL-------QQYSHDSADPGILVLLACGTISST 388
RG L NV+ P ++ A + K +L Q + + + + LA G +
Sbjct: 72 RGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGN------LASGGAAGA 125
Query: 389 CGQIASYPLALVRTRMQAQASIEGGPQLSMLGL---LRHILSQEGMRGLYRGIAPNFMKV 445
YPL RTR+ A + G + GL L I +G++GLY+G + +
Sbjct: 126 TSLCFVYPLDFARTRLAADVG-KAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGI 184
Query: 446 IPAVSISYVVYENMKQAL 463
I + + +Y+ K L
Sbjct: 185 IIYRAAYFGIYDTAKGML 202
>gi|21314739 solute carrier family 25, member 32 [Homo sapiens]
Length = 315
Score = 115 bits (288), Expect = 8e-26
Identities = 87/290 (30%), Positives = 135/290 (46%), Gaps = 17/290 (5%)
Query: 186 WKQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLN---ILGGLRSMVLEGGIRSLW 242
++ L+AG G +S PLD +K+ V R IL L ++ G+R L+
Sbjct: 23 YENLIAGVSGGVLSNLALHPLDLVKIRFAVSDGLELRPKYNGILHCLTTIWKLDGLRGLY 82
Query: 243 RGNGINVLKIAPESAIKFMAYEQIKR-AILGQQETLHVQERFVAGSLAGATAQTIIYPME 301
+G N+ + F Y IK G+ E L E V+ + AGA I P+
Sbjct: 83 QGVTPNIWGAGLSWGLYFFFYNAIKSYKTEGRAERLEATEYLVSAAEAGAMTLCITNPLW 142
Query: 302 VLKTRLTLRRTG-------QYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLA 354
V KTRL L+ QYKG+ D +I + EG R Y+G++P + G + +
Sbjct: 143 VTKTRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEGVRGLYKGFVPGLFGT-SHGALQFM 201
Query: 355 VYETLKNWWLQQYSH-DSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASIEGG 413
YE LK + Q + A + ++ +S A+YP +VR R+Q Q G
Sbjct: 202 AYELLKLKYNQHINRLPEAQLSTVEYISVAALSKIFAVAATYPYQVVRARLQDQHMFYSG 261
Query: 414 PQLSMLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQAL 463
++ ++ +EG+ G Y+GIAPN ++V PA I++VVYEN+ L
Sbjct: 262 ----VIDVITKTWRKEGVGGFYKGIAPNLIRVTPACCITFVVYENVSHFL 307
Score = 55.5 bits (132), Expect = 1e-07
Identities = 49/187 (26%), Positives = 86/187 (45%), Gaps = 13/187 (6%)
Query: 189 LVAGAVAGAVSRTGTAPL--DRLKVFMQVHASKTNRLNILGGLRSMVLE----GGIRSLW 242
LV+ A AGA++ T PL + ++ +Q A + G+ +++ G+R L+
Sbjct: 124 LVSAAEAGAMTLCITNPLWVTKTRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEGVRGLY 183
Query: 243 RGNGINVLKIAPESAIKFMAYEQIKRAILGQ-----QETLHVQERFVAGSLAGATAQTII 297
+G + L A++FMAYE +K + L E +L+ A
Sbjct: 184 KGF-VPGLFGTSHGALQFMAYELLKLKYNQHINRLPEAQLSTVEYISVAALSKIFAVAAT 242
Query: 298 YPMEVLKTRLTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYE 357
YP +V++ RL + Y G++D + +EG FY+G PN++ + P I VYE
Sbjct: 243 YPYQVVRARLQDQHMF-YSGVIDVITKTWRKEGVGGFYKGIAPNLIRVTPACCITFVVYE 301
Query: 358 TLKNWWL 364
+ ++ L
Sbjct: 302 NVSHFLL 308
>gi|55749577 solute carrier family 25 (mitochondrial carrier;
adenine nucleotide translocator), member 4 [Homo
sapiens]
Length = 298
Score = 115 bits (287), Expect = 1e-25
Identities = 87/293 (29%), Positives = 138/293 (47%), Gaps = 24/293 (8%)
Query: 187 KQLVAGAVAGAVSRTGTAPLDRLKVFMQV-HASKT-----NRLNILGGLRSMVLEGGIRS 240
K +AG VA AVS+T AP++R+K+ +QV HASK I+ + + E G S
Sbjct: 10 KDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLS 69
Query: 241 LWRGNGINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQERFVAGSL-----AGATAQT 295
WRGN NV++ P A+ F ++ K+ LG + R+ AG+L AGAT+
Sbjct: 70 FWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLC 129
Query: 296 IIYPMEVLKTRLTL-----RRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAG 350
+YP++ +TRL ++ GL DC +I + +G R Y+G+ +V GII Y
Sbjct: 130 FVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYRA 189
Query: 351 IDLAVYETLKNWWLQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASI 410
VY+T K D + I V + + SYP VR RM Q+
Sbjct: 190 AYFGVYDTAKG-----MLPDPKNVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGR 244
Query: 411 EGGPQL--SMLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQ 461
+G + + R I EG + ++G N ++ + + V+Y+ +K+
Sbjct: 245 KGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGMGGAFV-LVLYDEIKK 296
Score = 73.2 bits (178), Expect = 5e-13
Identities = 56/192 (29%), Positives = 88/192 (45%), Gaps = 12/192 (6%)
Query: 283 FVAGSLAGATAQTIIYPMEVLKTRLTLRRTG-------QYKGLLDCARRILEREGPRAFY 335
F+AG +A A ++T + P+E +K L ++ QYKG++DC RI + +G +F+
Sbjct: 12 FLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSFW 71
Query: 336 RGYLPNVLGIIPYAGIDLAVYETLKNWWLQQYS-HDSADPGILVLLACGTISSTCGQIAS 394
RG L NV+ P ++ A + K +L H LA G +
Sbjct: 72 RGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLCFV 131
Query: 395 YPLALVRTRMQAQASIEGGPQLSMLGL---LRHILSQEGMRGLYRGIAPNFMKVIPAVSI 451
YPL RTR+ A +G Q GL + I +G+RGLY+G + +I +
Sbjct: 132 YPLDFARTRLAADVG-KGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYRAA 190
Query: 452 SYVVYENMKQAL 463
+ VY+ K L
Sbjct: 191 YFGVYDTAKGML 202
>gi|186928856 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 110 bits (274), Expect = 4e-24
Identities = 73/285 (25%), Positives = 133/285 (46%), Gaps = 17/285 (5%)
Query: 190 VAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLN-------ILGGLRSMVLEGGIRSLW 242
VAG+V+G V+R +P D +K+ Q+ + +R + IL R ++ E G + W
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 243 RGNGINVLKIAPESAIKFMAYEQIKRAIL--GQQETLHVQERFVAGSLAGATAQTIIYPM 300
+G+ + A++F+++E + + + FV G LA A ++P+
Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPV 139
Query: 301 EVLKTRLTLRRTGQ-YKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETL 359
+VL+TR + + Y L + EGP+ FY+G P ++ I PYAG+ + Y +L
Sbjct: 140 DVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSL 199
Query: 360 KNWWLQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQA----QASIEGGPQ 415
K+ + + L L CG+ + + +YPL L + R+Q A G
Sbjct: 200 KHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQV 259
Query: 416 LSMLGLL---RHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYE 457
GL+ + +L +EG G ++G++P+ +K + + YE
Sbjct: 260 RRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
Score = 85.1 bits (209), Expect = 1e-16
Identities = 52/189 (27%), Positives = 96/189 (50%), Gaps = 20/189 (10%)
Query: 284 VAGSLAGATAQTIIYPMEVLKTRLTLRR--------TGQYKGLLDCARRILEREGPRAFY 335
VAGS++G + +I P +V+K R L+ + +Y G+L +R+IL+ EGP AF+
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 336 RGYLPNVLGIIPYAGIDLAVYETLKNWWLQQYSHDSADPGILVLLACGTISSTCGQIASY 395
+G++P + I Y + +E L + +D+ + V CG +++ + +
Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDARE--FSVHFVCGGLAACMATLTVH 137
Query: 396 PLALVRTRMQAQASIEGGPQLSMLGLLRHILS----QEGMRGLYRGIAPNFMKVIPAVSI 451
P+ ++RTR AQ G P++ LRH + EG + Y+G+AP + + P +
Sbjct: 138 PVDVLRTRFAAQ----GEPKV--YNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGL 191
Query: 452 SYVVYENMK 460
+ Y ++K
Sbjct: 192 QFSCYSSLK 200
Score = 67.0 bits (162), Expect = 3e-11
Identities = 44/186 (23%), Positives = 84/186 (45%), Gaps = 14/186 (7%)
Query: 190 VAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLNILGGLRSMVLEGGIRSLWRGNGINV 249
V G +A ++ P+D L+ + + +M G + ++G +
Sbjct: 123 VCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTL 182
Query: 250 LKIAPESAIKFMAYEQIKR----AILGQQETLHVQERFVAGSLAGATAQTIIYPMEVLKT 305
+ I P + ++F Y +K AI + + + + GS AG ++T+ YP+++ K
Sbjct: 183 IAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKK 242
Query: 306 RLTLR----------RTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAV 355
RL + + +YKGL+DCA+++L++EG F++G P++L G
Sbjct: 243 RLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFS 302
Query: 356 YETLKN 361
YE N
Sbjct: 303 YEFFCN 308
Score = 35.4 bits (80), Expect = 0.11
Identities = 27/103 (26%), Positives = 47/103 (45%), Gaps = 14/103 (13%)
Query: 171 VPDEFSKQEKLTGMWWKQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRL------- 223
+P E K E L + L+ G+ AG +S+T T PLD K +QV + R
Sbjct: 207 IPAEGKKNENL-----QNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRR 261
Query: 224 --NILGGLRSMVLEGGIRSLWRGNGINVLKIAPESAIKFMAYE 264
++ + ++ + G ++G ++LK A + F +YE
Sbjct: 262 YKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
>gi|186928860 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 110 bits (274), Expect = 4e-24
Identities = 73/285 (25%), Positives = 133/285 (46%), Gaps = 17/285 (5%)
Query: 190 VAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLN-------ILGGLRSMVLEGGIRSLW 242
VAG+V+G V+R +P D +K+ Q+ + +R + IL R ++ E G + W
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 243 RGNGINVLKIAPESAIKFMAYEQIKRAIL--GQQETLHVQERFVAGSLAGATAQTIIYPM 300
+G+ + A++F+++E + + + FV G LA A ++P+
Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPV 139
Query: 301 EVLKTRLTLRRTGQ-YKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETL 359
+VL+TR + + Y L + EGP+ FY+G P ++ I PYAG+ + Y +L
Sbjct: 140 DVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSL 199
Query: 360 KNWWLQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQA----QASIEGGPQ 415
K+ + + L L CG+ + + +YPL L + R+Q A G
Sbjct: 200 KHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQV 259
Query: 416 LSMLGLL---RHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYE 457
GL+ + +L +EG G ++G++P+ +K + + YE
Sbjct: 260 RRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
Score = 85.1 bits (209), Expect = 1e-16
Identities = 52/189 (27%), Positives = 96/189 (50%), Gaps = 20/189 (10%)
Query: 284 VAGSLAGATAQTIIYPMEVLKTRLTLRR--------TGQYKGLLDCARRILEREGPRAFY 335
VAGS++G + +I P +V+K R L+ + +Y G+L +R+IL+ EGP AF+
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 336 RGYLPNVLGIIPYAGIDLAVYETLKNWWLQQYSHDSADPGILVLLACGTISSTCGQIASY 395
+G++P + I Y + +E L + +D+ + V CG +++ + +
Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDARE--FSVHFVCGGLAACMATLTVH 137
Query: 396 PLALVRTRMQAQASIEGGPQLSMLGLLRHILS----QEGMRGLYRGIAPNFMKVIPAVSI 451
P+ ++RTR AQ G P++ LRH + EG + Y+G+AP + + P +
Sbjct: 138 PVDVLRTRFAAQ----GEPKV--YNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGL 191
Query: 452 SYVVYENMK 460
+ Y ++K
Sbjct: 192 QFSCYSSLK 200
Score = 67.0 bits (162), Expect = 3e-11
Identities = 44/186 (23%), Positives = 84/186 (45%), Gaps = 14/186 (7%)
Query: 190 VAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLNILGGLRSMVLEGGIRSLWRGNGINV 249
V G +A ++ P+D L+ + + +M G + ++G +
Sbjct: 123 VCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTL 182
Query: 250 LKIAPESAIKFMAYEQIKR----AILGQQETLHVQERFVAGSLAGATAQTIIYPMEVLKT 305
+ I P + ++F Y +K AI + + + + GS AG ++T+ YP+++ K
Sbjct: 183 IAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKK 242
Query: 306 RLTLR----------RTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAV 355
RL + + +YKGL+DCA+++L++EG F++G P++L G
Sbjct: 243 RLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFS 302
Query: 356 YETLKN 361
YE N
Sbjct: 303 YEFFCN 308
Score = 35.4 bits (80), Expect = 0.11
Identities = 27/103 (26%), Positives = 47/103 (45%), Gaps = 14/103 (13%)
Query: 171 VPDEFSKQEKLTGMWWKQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRL------- 223
+P E K E L + L+ G+ AG +S+T T PLD K +QV + R
Sbjct: 207 IPAEGKKNENL-----QNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRR 261
Query: 224 --NILGGLRSMVLEGGIRSLWRGNGINVLKIAPESAIKFMAYE 264
++ + ++ + G ++G ++LK A + F +YE
Sbjct: 262 YKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
>gi|186928858 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 110 bits (274), Expect = 4e-24
Identities = 73/285 (25%), Positives = 133/285 (46%), Gaps = 17/285 (5%)
Query: 190 VAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLN-------ILGGLRSMVLEGGIRSLW 242
VAG+V+G V+R +P D +K+ Q+ + +R + IL R ++ E G + W
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 243 RGNGINVLKIAPESAIKFMAYEQIKRAIL--GQQETLHVQERFVAGSLAGATAQTIIYPM 300
+G+ + A++F+++E + + + FV G LA A ++P+
Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPV 139
Query: 301 EVLKTRLTLRRTGQ-YKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETL 359
+VL+TR + + Y L + EGP+ FY+G P ++ I PYAG+ + Y +L
Sbjct: 140 DVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSL 199
Query: 360 KNWWLQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQA----QASIEGGPQ 415
K+ + + L L CG+ + + +YPL L + R+Q A G
Sbjct: 200 KHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQV 259
Query: 416 LSMLGLL---RHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYE 457
GL+ + +L +EG G ++G++P+ +K + + YE
Sbjct: 260 RRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
Score = 85.1 bits (209), Expect = 1e-16
Identities = 52/189 (27%), Positives = 96/189 (50%), Gaps = 20/189 (10%)
Query: 284 VAGSLAGATAQTIIYPMEVLKTRLTLRR--------TGQYKGLLDCARRILEREGPRAFY 335
VAGS++G + +I P +V+K R L+ + +Y G+L +R+IL+ EGP AF+
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 336 RGYLPNVLGIIPYAGIDLAVYETLKNWWLQQYSHDSADPGILVLLACGTISSTCGQIASY 395
+G++P + I Y + +E L + +D+ + V CG +++ + +
Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDARE--FSVHFVCGGLAACMATLTVH 137
Query: 396 PLALVRTRMQAQASIEGGPQLSMLGLLRHILS----QEGMRGLYRGIAPNFMKVIPAVSI 451
P+ ++RTR AQ G P++ LRH + EG + Y+G+AP + + P +
Sbjct: 138 PVDVLRTRFAAQ----GEPKV--YNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGL 191
Query: 452 SYVVYENMK 460
+ Y ++K
Sbjct: 192 QFSCYSSLK 200
Score = 67.0 bits (162), Expect = 3e-11
Identities = 44/186 (23%), Positives = 84/186 (45%), Gaps = 14/186 (7%)
Query: 190 VAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLNILGGLRSMVLEGGIRSLWRGNGINV 249
V G +A ++ P+D L+ + + +M G + ++G +
Sbjct: 123 VCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTL 182
Query: 250 LKIAPESAIKFMAYEQIKR----AILGQQETLHVQERFVAGSLAGATAQTIIYPMEVLKT 305
+ I P + ++F Y +K AI + + + + GS AG ++T+ YP+++ K
Sbjct: 183 IAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKK 242
Query: 306 RLTLR----------RTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAV 355
RL + + +YKGL+DCA+++L++EG F++G P++L G
Sbjct: 243 RLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFS 302
Query: 356 YETLKN 361
YE N
Sbjct: 303 YEFFCN 308
Score = 35.4 bits (80), Expect = 0.11
Identities = 27/103 (26%), Positives = 47/103 (45%), Gaps = 14/103 (13%)
Query: 171 VPDEFSKQEKLTGMWWKQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRL------- 223
+P E K E L + L+ G+ AG +S+T T PLD K +QV + R
Sbjct: 207 IPAEGKKNENL-----QNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRR 261
Query: 224 --NILGGLRSMVLEGGIRSLWRGNGINVLKIAPESAIKFMAYE 264
++ + ++ + G ++G ++LK A + F +YE
Sbjct: 262 YKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
>gi|58197562 solute carrier family 25, member 30 [Homo sapiens]
Length = 291
Score = 109 bits (273), Expect = 5e-24
Identities = 82/292 (28%), Positives = 136/292 (46%), Gaps = 15/292 (5%)
Query: 181 LTGMWWKQLVAGAVAGAVSRTGTAPLD----RLKVFMQVHASKTNRLNILGGLRSMVLEG 236
++ + WK V G +A + GT P+D RL++ Q + +K + G L ++V G
Sbjct: 1 MSALNWKPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIG 60
Query: 237 ---GIRSLWRGNGINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQERFVAGSLAGATA 293
G+++L+ G +L+ A IK Y+ +KR + + E + + G L+G +
Sbjct: 61 REEGLKALYSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVICGILSGVIS 120
Query: 294 QTIIYPMEVLKTRLTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDL 353
TI P +VLK R+ + G++ I ++EG R ++G G++L
Sbjct: 121 STIANPTDVLKIRMQAQSNTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVEL 180
Query: 354 AVYE-TLKNWWLQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASIEG 412
VY+ T K+ L D+ L CG G +AS P+ +VRTRM Q +
Sbjct: 181 PVYDITKKHLILSGLMGDTVYTHFLSSFTCG----LAGALASNPVDVVRTRMMNQRVLRD 236
Query: 413 GPQLSMLGLLRHIL---SQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQ 461
G G L +L EG LY+G PN++++ P I +V YE +K+
Sbjct: 237 GRCSGYTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLKK 288
Score = 87.8 bits (216), Expect = 2e-17
Identities = 58/190 (30%), Positives = 99/190 (52%), Gaps = 17/190 (8%)
Query: 283 FVAGSLAGATAQTIIYPMEVLKTRLTLR--------RTGQYKGLLDCARRILEREGPRAF 334
FV G LA TA+ +P+++ KTRL ++ + +Y+G+L RI EG +A
Sbjct: 9 FVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLKAL 68
Query: 335 YRGYLPNVLGIIPYAGIDLAVYETLKNWWLQQYSHDSADPGILVLLACGTISSTCGQIAS 394
Y G P +L Y I + Y++LK ++++ ++ ++ + G ISST
Sbjct: 69 YSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVICGILSGVISSTIAN--- 125
Query: 395 YPLALVRTRMQAQAS-IEGGPQLSMLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISY 453
P +++ RMQAQ++ I+GG M+G +I QEG RGL++G++ + V +
Sbjct: 126 -PTDVLKIRMQAQSNTIQGG----MIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVEL 180
Query: 454 VVYENMKQAL 463
VY+ K+ L
Sbjct: 181 PVYDITKKHL 190
>gi|157388989 solute carrier family 25, member 36 isoform a [Homo
sapiens]
Length = 311
Score = 109 bits (273), Expect = 5e-24
Identities = 89/301 (29%), Positives = 143/301 (47%), Gaps = 39/301 (12%)
Query: 189 LVAGAVAGAVSRTGTAPLDRLKVFMQ-----VHASKTNRLNILGG--------------L 229
L AG G V T PL+ +K +Q ++ S+ +LN + G L
Sbjct: 10 LFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEV-QLNTMAGASVNRVVSPGPLHCL 68
Query: 230 RSMVLEGGIRSLWRGNGINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQERFVAGSLA 289
+ ++ + G RSL+RG G N++ +AP AI F AY K + + Q ++ ++A
Sbjct: 69 KVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMA 128
Query: 290 GATAQTIIYPMEVLKTRLTL--RRTGQYK-GLLDCARRILEREGPRAFYRGYLPNVLGII 346
G TA T P+ ++KTRL L R G+ + G +C R++ + +G + FYRG + GI
Sbjct: 129 GFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASYAGIS 188
Query: 347 PYAGIDLAVYETLKNWWLQ----------QYSHDSADPGILVLLACGTISSTCGQIASYP 396
I +YE++K L+ + S A + ++LA T S TC +YP
Sbjct: 189 ETV-IHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAAT-SKTCATTIAYP 246
Query: 397 LALVRTRMQAQASIEGGPQLSMLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVY 456
+VRTR++ EG S L ++ +EG LYRG+ + ++ IP +I Y
Sbjct: 247 HEVVRTRLRE----EGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATY 302
Query: 457 E 457
E
Sbjct: 303 E 303
Score = 52.4 bits (124), Expect = 9e-07
Identities = 35/103 (33%), Positives = 49/103 (47%), Gaps = 16/103 (15%)
Query: 377 LVLLACGTISSTCGQIASYPLALVRTRMQ----------------AQASIEGGPQLSMLG 420
LV L G T G I + PL +V+TR+Q A AS+ L
Sbjct: 7 LVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLH 66
Query: 421 LLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQAL 463
L+ IL +EG R L+RG+ PN + V P+ +I + Y N K+ L
Sbjct: 67 CLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKL 109
>gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Homo
sapiens]
Length = 325
Score = 106 bits (264), Expect = 5e-23
Identities = 80/293 (27%), Positives = 139/293 (47%), Gaps = 16/293 (5%)
Query: 180 KLTGMWWKQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRL-------NILGGLRSM 232
+++G+ WK V G +A V+ GT P+D K +QV + + L +
Sbjct: 35 EMSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRI 94
Query: 233 VLEGGIRSLWRGNGINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQERFVAGSLAGAT 292
E G+ +L+ G +L+ A IK Y+ +KR + + E + + G ++G
Sbjct: 95 CKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVI 154
Query: 293 AQTIIYPMEVLKTRLTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGID 352
+ TI P +VLK R+ + + ++ I ++EG R +RG +P G++
Sbjct: 155 SSTIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVE 214
Query: 353 LAVYE-TLKNWWLQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASIE 411
L VY+ T K+ L D+ + CG G +AS P+ +VRTRM Q +I
Sbjct: 215 LPVYDITKKHLILSGMMGDTILTHFVSSFTCG----LAGALASNPVDVVRTRMMNQRAIV 270
Query: 412 GGPQL---SMLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQ 461
G L ++ G+L+ + EG LY+G PN++++ P I ++ YE +K+
Sbjct: 271 GHVDLYKGTVDGILK-MWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKR 322
Score = 94.0 bits (232), Expect = 3e-19
Identities = 58/189 (30%), Positives = 94/189 (49%), Gaps = 15/189 (7%)
Query: 283 FVAGSLAGATAQTIIYPMEVLKTRLTLRRTG--------QYKGLLDCARRILEREGPRAF 334
FV G LA A+ +P+++ KTRL ++ +Y+G+ RI + EG A
Sbjct: 44 FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLAL 103
Query: 335 YRGYLPNVLGIIPYAGIDLAVYETLKNWWLQQYSHDSADPGILVLLACGTISSTCGQIAS 394
Y G P +L Y I + +Y++LK ++++ D +L+ + CG +S +
Sbjct: 104 YSGIAPALLRQASYGTIKIGIYQSLKRLFVERLE----DETLLINMICGVVSGVISSTIA 159
Query: 395 YPLALVRTRMQAQASIEGGPQLSMLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYV 454
P +++ RMQAQ S+ G SM+G I QEG RGL+RG+ P + V +
Sbjct: 160 NPTDVLKIRMQAQGSLFQG---SMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELP 216
Query: 455 VYENMKQAL 463
VY+ K+ L
Sbjct: 217 VYDITKKHL 225
>gi|13259543 solute carrier family 25, member 14 isoform UCP5S [Homo
sapiens]
Length = 322
Score = 106 bits (264), Expect = 5e-23
Identities = 80/293 (27%), Positives = 139/293 (47%), Gaps = 16/293 (5%)
Query: 180 KLTGMWWKQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRL-------NILGGLRSM 232
+++G+ WK V G +A V+ GT P+D K +QV + + L +
Sbjct: 32 EMSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRI 91
Query: 233 VLEGGIRSLWRGNGINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQERFVAGSLAGAT 292
E G+ +L+ G +L+ A IK Y+ +KR + + E + + G ++G
Sbjct: 92 CKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVI 151
Query: 293 AQTIIYPMEVLKTRLTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGID 352
+ TI P +VLK R+ + + ++ I ++EG R +RG +P G++
Sbjct: 152 SSTIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVE 211
Query: 353 LAVYE-TLKNWWLQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASIE 411
L VY+ T K+ L D+ + CG G +AS P+ +VRTRM Q +I
Sbjct: 212 LPVYDITKKHLILSGMMGDTILTHFVSSFTCG----LAGALASNPVDVVRTRMMNQRAIV 267
Query: 412 GGPQL---SMLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQ 461
G L ++ G+L+ + EG LY+G PN++++ P I ++ YE +K+
Sbjct: 268 GHVDLYKGTVDGILK-MWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKR 319
Score = 94.7 bits (234), Expect = 2e-19
Identities = 65/227 (28%), Positives = 107/227 (47%), Gaps = 22/227 (9%)
Query: 252 IAPESAIKFMAYEQIKRAILGQQETLHVQER-------FVAGSLAGATAQTIIYPMEVLK 304
I P + F+ + A++ Q+ T E FV G LA A+ +P+++ K
Sbjct: 3 IFPGIILIFLRVKFATAAVIHQKSTTVSHEMSGLNWKPFVYGGLASIVAEFGTFPVDLTK 62
Query: 305 TRLTLRRTG--------QYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVY 356
TRL ++ +Y+G+ RI + EG A Y G P +L Y I + +Y
Sbjct: 63 TRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSGIAPALLRQASYGTIKIGIY 122
Query: 357 ETLKNWWLQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASIEGGPQL 416
++LK ++++ D +L+ + CG +S + P +++ RMQAQ S+ G
Sbjct: 123 QSLKRLFVERLE----DETLLINMICGVVSGVISSTIANPTDVLKIRMQAQGSLFQG--- 175
Query: 417 SMLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQAL 463
SM+G I QEG RGL+RG+ P + V + VY+ K+ L
Sbjct: 176 SMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKKHL 222
>gi|157388991 solute carrier family 25, member 36 isoform b [Homo
sapiens]
Length = 310
Score = 105 bits (263), Expect = 7e-23
Identities = 89/301 (29%), Positives = 143/301 (47%), Gaps = 40/301 (13%)
Query: 189 LVAGAVAGAVSRTGTAPLDRLKVFMQ-----VHASKTNRLNILGG--------------L 229
L AG G V T PL+ +K +Q ++ S+ +LN + G L
Sbjct: 10 LFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEV-QLNTMAGASVNRVVSPGPLHCL 68
Query: 230 RSMVLEGGIRSLWRGNGINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQERFVAGSLA 289
+ ++ + G RSL+RG G N++ +AP AI F AY K + + Q ++ ++A
Sbjct: 69 KVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMA 128
Query: 290 GATAQTIIYPMEVLKTRLTL--RRTGQYK-GLLDCARRILEREGPRAFYRGYLPNVLGII 346
G TA T P+ ++KTRL L R G+ + G +C R++ + +G + FYRG + GI
Sbjct: 129 GFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASYAGIS 188
Query: 347 PYAGIDLAVYETLKNWWLQ----------QYSHDSADPGILVLLACGTISSTCGQIASYP 396
I +YE++K L+ + S A + ++LA T S TC +YP
Sbjct: 189 ETV-IHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAAT-SKTCATTIAYP 246
Query: 397 LALVRTRMQAQASIEGGPQLSMLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVY 456
+VRTR++ EG S L ++ +EG LYRG+ + ++ IP +I Y
Sbjct: 247 -HVVRTRLRE----EGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATY 301
Query: 457 E 457
E
Sbjct: 302 E 302
Score = 52.4 bits (124), Expect = 9e-07
Identities = 35/103 (33%), Positives = 49/103 (47%), Gaps = 16/103 (15%)
Query: 377 LVLLACGTISSTCGQIASYPLALVRTRMQ----------------AQASIEGGPQLSMLG 420
LV L G T G I + PL +V+TR+Q A AS+ L
Sbjct: 7 LVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLH 66
Query: 421 LLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQAL 463
L+ IL +EG R L+RG+ PN + V P+ +I + Y N K+ L
Sbjct: 67 CLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKL 109
>gi|7706306 solute carrier family 25, member 39 isoform b [Homo
sapiens]
Length = 351
Score = 102 bits (253), Expect = 1e-21
Identities = 66/232 (28%), Positives = 112/232 (48%), Gaps = 9/232 (3%)
Query: 232 MVLEGGIRSLWRGNGINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQERFVAGSLAGA 291
+V G R+LW G ++ P +AI F AY+Q+K + G+ T + VAG+LA
Sbjct: 106 IVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGALARL 165
Query: 292 TAQTIIYPMEVLKTRLTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGI 351
T+I P+E+++T+L + Y+ L C R + + G R+ + G+ P L +P++ +
Sbjct: 166 GTVTVISPLELMRTKLQAQHV-SYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPFSAL 224
Query: 352 DLAVYETLKNWWLQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASIE 411
YE +K+W D G + G IS T + + P +V+T+ Q
Sbjct: 225 YWFNYELVKSWLNGFRPKDQTSVG--MSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAM 282
Query: 412 GGPQLSMLG------LLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYE 457
+++ L LLR I ++ G +GL+ G P +K P+ +I YE
Sbjct: 283 EAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYE 334
Score = 73.2 bits (178), Expect = 5e-13
Identities = 54/190 (28%), Positives = 90/190 (47%), Gaps = 17/190 (8%)
Query: 189 LVAGAVAGAVSRTGT----APLDRLKVFMQVHASKTNRLNILGGLRSMVLEGGIRSLWRG 244
L A VAGA++R GT +PL+ ++ +Q L +R+ V +GG RSLW G
Sbjct: 153 LYAPMVAGALARLGTVTVISPLELMRTKLQAQHVSYRELGAC--VRTAVAQGGWRSLWLG 210
Query: 245 NGINVLKIAPESAIKFMAYEQIKRAILG--QQETLHVQERFVAGSLAGATAQTIIYPMEV 302
G L+ P SA+ + YE +K + G ++ V FVAG ++G A + P +V
Sbjct: 211 WGPTALRDVPFSALYWFNYELVKSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDV 270
Query: 303 LKTRLTLRRTGQYKGLLD---------CARRILEREGPRAFYRGYLPNVLGIIPYAGIDL 353
+KT+ + ++ RRI G + + G+LP ++ P I +
Sbjct: 271 VKTQRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMI 330
Query: 354 AVYETLKNWW 363
+ YE K+++
Sbjct: 331 STYEFGKSFF 340
Score = 29.6 bits (65), Expect = 6.1
Identities = 12/39 (30%), Positives = 21/39 (53%)
Query: 425 ILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQAL 463
I+ EG R L+ G+ + +PA +I + Y+ +K L
Sbjct: 106 IVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFL 144
>gi|219555665 solute carrier family 25, member 39 isoform a [Homo
sapiens]
Length = 359
Score = 102 bits (253), Expect = 1e-21
Identities = 66/232 (28%), Positives = 112/232 (48%), Gaps = 9/232 (3%)
Query: 232 MVLEGGIRSLWRGNGINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQERFVAGSLAGA 291
+V G R+LW G ++ P +AI F AY+Q+K + G+ T + VAG+LA
Sbjct: 114 IVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGALARL 173
Query: 292 TAQTIIYPMEVLKTRLTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGI 351
T+I P+E+++T+L + Y+ L C R + + G R+ + G+ P L +P++ +
Sbjct: 174 GTVTVISPLELMRTKLQAQHV-SYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPFSAL 232
Query: 352 DLAVYETLKNWWLQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASIE 411
YE +K+W D G + G IS T + + P +V+T+ Q
Sbjct: 233 YWFNYELVKSWLNGFRPKDQTSVG--MSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAM 290
Query: 412 GGPQLSMLG------LLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYE 457
+++ L LLR I ++ G +GL+ G P +K P+ +I YE
Sbjct: 291 EAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYE 342
Score = 73.2 bits (178), Expect = 5e-13
Identities = 54/190 (28%), Positives = 90/190 (47%), Gaps = 17/190 (8%)
Query: 189 LVAGAVAGAVSRTGT----APLDRLKVFMQVHASKTNRLNILGGLRSMVLEGGIRSLWRG 244
L A VAGA++R GT +PL+ ++ +Q L +R+ V +GG RSLW G
Sbjct: 161 LYAPMVAGALARLGTVTVISPLELMRTKLQAQHVSYRELGAC--VRTAVAQGGWRSLWLG 218
Query: 245 NGINVLKIAPESAIKFMAYEQIKRAILG--QQETLHVQERFVAGSLAGATAQTIIYPMEV 302
G L+ P SA+ + YE +K + G ++ V FVAG ++G A + P +V
Sbjct: 219 WGPTALRDVPFSALYWFNYELVKSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDV 278
Query: 303 LKTRLTLRRTGQYKGLLD---------CARRILEREGPRAFYRGYLPNVLGIIPYAGIDL 353
+KT+ + ++ RRI G + + G+LP ++ P I +
Sbjct: 279 VKTQRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMI 338
Query: 354 AVYETLKNWW 363
+ YE K+++
Sbjct: 339 STYEFGKSFF 348
Score = 29.6 bits (65), Expect = 6.1
Identities = 12/39 (30%), Positives = 21/39 (53%)
Query: 425 ILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQAL 463
I+ EG R L+ G+ + +PA +I + Y+ +K L
Sbjct: 114 IVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFL 152
>gi|14150082 mitochondrial carrier protein MGC4399 [Homo sapiens]
Length = 321
Score = 99.8 bits (247), Expect = 5e-21
Identities = 87/305 (28%), Positives = 135/305 (44%), Gaps = 45/305 (14%)
Query: 189 LVAGAVAGAVSRTGTAPLDRLKV-------------FMQVH------ASKTNRLNILGGL 229
L AG G V T PL+ +K + QVH A ++ GL
Sbjct: 15 LFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPGL 74
Query: 230 ----RSMVLEGGIRSLWRGNGINVLKIAPESAIKFMAYEQIKRAILG----QQETLHVQE 281
+S++ + G +SL+RG G N++ +AP A+ F Y + K G +H+
Sbjct: 75 FQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPNSNIVHI-- 132
Query: 282 RFVAGSLAGATAQTIIYPMEVLKTRLTLR---RTGQYKGLLDCARRILEREGPRAFYRGY 338
F AGS A T +++ P+ ++KTR+ L R + L CAR + + EG R FYRG
Sbjct: 133 -FSAGSAAFIT-NSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGL 190
Query: 339 LPNVLGIIPYAGIDLAVYETLKNWWLQQYSHDSAD------PGILVLLACGTISSTCGQI 392
+ GI I A+YE+LK + + SA+ L+A +S C
Sbjct: 191 TASYAGISETI-ICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASC 249
Query: 393 ASYPLALVRTRMQAQASIEGGPQLSMLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSIS 452
+YP ++RTR++ EG S + R + +EG YRG+ ++ IP +I
Sbjct: 250 IAYPHEVIRTRLRE----EGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIV 305
Query: 453 YVVYE 457
YE
Sbjct: 306 LSTYE 310
Score = 87.4 bits (215), Expect = 2e-17
Identities = 58/216 (26%), Positives = 102/216 (47%), Gaps = 30/216 (13%)
Query: 272 GQQETLHVQERFVAGSLAGATAQTIIYPMEVLKTRL------------------------ 307
GQQ+ + F AG G P+EV+KTRL
Sbjct: 5 GQQKENTLLHLF-AGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAG 63
Query: 308 TLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETLKNWWLQQY 367
+R T GL + ILE+EGP++ +RG PN++G+ P + A Y K + +
Sbjct: 64 MVRPTSVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIF 123
Query: 368 SHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASIEGGPQLSMLGLLRHILS 427
+S I+ + + G+ + + + P+ +V+TRMQ + + G Q++ L R++
Sbjct: 124 VPNS---NIVHIFSAGSAAFITNSLMN-PIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQ 179
Query: 428 QEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQAL 463
EG+RG YRG+ ++ + + I + +YE++K+ L
Sbjct: 180 TEGIRGFYRGLTASYAGISETI-ICFAIYESLKKYL 214
Score = 59.7 bits (143), Expect = 6e-09
Identities = 48/162 (29%), Positives = 76/162 (46%), Gaps = 14/162 (8%)
Query: 208 RLKVFMQVHASKTNRLNILGGLRSMVLEGGIRSLWRGNGINVLKIAPESAIKFMAYEQIK 267
R+++ +V SK ++N L R + GIR +RG + I+ E+ I F YE +K
Sbjct: 155 RMQLEQKVRGSK--QMNTLQCARYVYQTEGIRGFYRGLTASYAGIS-ETIICFAIYESLK 211
Query: 268 RAILG----------QQETLHVQERFVAGSLAGATAQTIIYPMEVLKTRLTLRRTGQYKG 317
+ + ++ + A +L+ A I YP EV++TRL T +YK
Sbjct: 212 KYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASCIAYPHEVIRTRLREEGT-KYKS 270
Query: 318 LLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETL 359
+ AR + EG AFYRG ++ IP I L+ YE +
Sbjct: 271 FVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLSTYELI 312
>gi|82775373 solute carrier family 25, member 37 [Homo sapiens]
Length = 338
Score = 99.4 bits (246), Expect = 6e-21
Identities = 76/286 (26%), Positives = 129/286 (45%), Gaps = 18/286 (6%)
Query: 189 LVAGAVAGAVSRTGTAPLDRLKVFMQVHAS--KTNRLNILGGLRSMVLEGGIRSLWRGNG 246
+ AGA+AG + + P+D +K MQ + K +I G L+ ++ G RG
Sbjct: 49 MTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVN 108
Query: 247 INVLKIAPESAIKFMAYEQIKRA---ILGQQETLHVQERFVAGSLAGATAQTIIYPMEVL 303
+ ++ P A+ F YE +KR + Q H+ +AGS+A ++ P EV+
Sbjct: 109 VMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANG-IAGSMATLLHDAVMNPAEVV 167
Query: 304 KTRLTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETLKNWW 363
K RL + + Q++ + C R + EG AFYR Y + IP+ I YE L+
Sbjct: 168 KQRLQMYNS-QHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQE-- 224
Query: 364 LQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASIE------GGPQLS 417
Q H + +P ++ G ++ A+ PL + +T + Q ++ G
Sbjct: 225 -QVNPHRTYNPQSHII--SGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLSG 281
Query: 418 MLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQAL 463
M R + G+ G ++GI + +P+ +IS+ VYE K L
Sbjct: 282 MANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFL 327
Score = 57.0 bits (136), Expect = 4e-08
Identities = 44/186 (23%), Positives = 78/186 (41%), Gaps = 9/186 (4%)
Query: 279 VQERFVAGSLAGATAQTIIYPMEVLKTR---LTLRRTGQYKGLLDCARRILEREGPRAFY 335
V AG++AG +++YP++ +KTR L+ QY + ++I+ EG
Sbjct: 45 VSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPL 104
Query: 336 RGYLPNVLGIIPYAGIDLAVYETLKNWWLQQYSHDSADPGILVLLACGTISSTCGQIASY 395
RG ++G P + A YE +K + H L G++++
Sbjct: 105 RGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSH--LANGIAGSMATLLHDAVMN 162
Query: 396 PLALVRTRMQAQASIEGGPQLSMLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVV 455
P +V+ R+Q S S + +R + EG+ YR IP SI ++
Sbjct: 163 PAEVVKQRLQMYNS----QHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFIT 218
Query: 456 YENMKQ 461
YE +++
Sbjct: 219 YEFLQE 224
Score = 43.9 bits (102), Expect = 3e-04
Identities = 26/99 (26%), Positives = 44/99 (44%)
Query: 365 QQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASIEGGPQLSMLGLLRH 424
+ Y + + + G ++ YP+ V+TRMQ+ + S+ G L+
Sbjct: 34 EDYENLPTSASVSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKK 93
Query: 425 ILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQAL 463
I+ EG RG+ M PA ++ + YENMK+ L
Sbjct: 94 IMRTEGFWRPLRGVNVMIMGAGPAHAMYFACYENMKRTL 132
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,104,095
Number of Sequences: 37866
Number of extensions: 745873
Number of successful extensions: 3215
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 117
Number of HSP's successfully gapped in prelim test: 72
Number of HSP's that attempted gapping in prelim test: 2300
Number of HSP's gapped (non-prelim): 445
length of query: 468
length of database: 18,247,518
effective HSP length: 106
effective length of query: 362
effective length of database: 14,233,722
effective search space: 5152607364
effective search space used: 5152607364
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.