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Search of human proteins with 4826798
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4826798 potassium inwardly-rectifying channel J4 [Homo
sapiens]
(445 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4826798 potassium inwardly-rectifying channel J4 [Homo sapiens] 900 0.0
gi|23110984 potassium inwardly-rectifying channel J4 [Homo sapiens] 900 0.0
gi|23110982 potassium inwardly-rectifying channel, subfamily J, ... 555 e-158
gi|239758082 PREDICTED: similar to thyrotoxic periodic paralysis... 547 e-156
gi|239757993 PREDICTED: similar to inward rectifying K+ channel ... 524 e-149
gi|239757991 PREDICTED: similar to inward rectifying K+ channel ... 524 e-149
gi|239751249 PREDICTED: hypothetical protein XP_002347768 [Homo ... 524 e-149
gi|4504835 potassium inwardly-rectifying channel J2 [Homo sapiens] 523 e-148
gi|7019439 potassium inwardly-rectifying channel J14 [Homo sapiens] 479 e-135
gi|25777635 potassium inwardly-rectifying channel J14 [Homo sapi... 479 e-135
gi|24797141 potassium inwardly-rectifying channel J5 [Homo sapiens] 389 e-108
gi|25121970 potassium inwardly-rectifying channel subfamily J9 [... 382 e-106
gi|4504843 potassium inwardly-rectifying channel J6 [Homo sapiens] 380 e-105
gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens] 358 7e-99
gi|4826802 potassium inwardly-rectifying channel J8 [Homo sapiens] 329 4e-90
gi|62388888 potassium inwardly-rectifying channel J11 [Homo sapi... 328 6e-90
gi|8923823 potassium inwardly-rectifying channel J16 [Homo sapiens] 322 6e-88
gi|25777630 potassium inwardly-rectifying channel J16 [Homo sapi... 322 6e-88
gi|25777628 potassium inwardly-rectifying channel J16 [Homo sapi... 322 6e-88
gi|24497471 potassium inwardly-rectifying channel J1 isoform b [... 312 3e-85
gi|24497467 potassium inwardly-rectifying channel J1 isoform b [... 312 3e-85
gi|4504837 potassium inwardly-rectifying channel J1 isoform a [H... 312 3e-85
gi|148539892 potassium inwardly-rectifying channel J1 isoform b ... 312 3e-85
gi|24497473 potassium inwardly-rectifying channel J1 isoform b [... 312 3e-85
gi|25121966 potassium inwardly-rectifying channel, subfamily J, ... 268 1e-71
gi|21361127 potassium inwardly-rectifying channel J15 [Homo sapi... 266 2e-71
gi|25777640 potassium inwardly-rectifying channel J15 [Homo sapi... 266 2e-71
gi|25777638 potassium inwardly-rectifying channel J15 [Homo sapi... 266 2e-71
gi|156119627 potassium inwardly-rectifying channel J13 [Homo sap... 176 5e-44
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 35 0.14
>gi|4826798 potassium inwardly-rectifying channel J4 [Homo sapiens]
Length = 445
Score = 900 bits (2325), Expect = 0.0
Identities = 445/445 (100%), Positives = 445/445 (100%)
Query: 1 MHGHSRNGQAHVPRRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLM 60
MHGHSRNGQAHVPRRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLM
Sbjct: 1 MHGHSRNGQAHVPRRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLM 60
Query: 61 IFSAAFLVSWLFFGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNG 120
IFSAAFLVSWLFFGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNG
Sbjct: 61 IFSAAFLVSWLFFGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNG 120
Query: 121 FLGAFLFSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKK 180
FLGAFLFSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKK
Sbjct: 121 FLGAFLFSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKK 180
Query: 181 RAQTLLFSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQR 240
RAQTLLFSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQR
Sbjct: 181 RAQTLLFSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQR 240
Query: 241 DLNVGYDIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMT 300
DLNVGYDIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMT
Sbjct: 241 DLNVGYDIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMT 300
Query: 301 TQARSSYLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESKITV 360
TQARSSYLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESKITV
Sbjct: 301 TQARSSYLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESKITV 360
Query: 361 LPAPPPPPSAFCYENELALMSQEEEEMEEEAAAAAAVAAGLGLEAGSKEEAGIIRMLEFG 420
LPAPPPPPSAFCYENELALMSQEEEEMEEEAAAAAAVAAGLGLEAGSKEEAGIIRMLEFG
Sbjct: 361 LPAPPPPPSAFCYENELALMSQEEEEMEEEAAAAAAVAAGLGLEAGSKEEAGIIRMLEFG 420
Query: 421 SHLDLERMQASLPLDNISYRRESAI 445
SHLDLERMQASLPLDNISYRRESAI
Sbjct: 421 SHLDLERMQASLPLDNISYRRESAI 445
>gi|23110984 potassium inwardly-rectifying channel J4 [Homo sapiens]
Length = 445
Score = 900 bits (2325), Expect = 0.0
Identities = 445/445 (100%), Positives = 445/445 (100%)
Query: 1 MHGHSRNGQAHVPRRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLM 60
MHGHSRNGQAHVPRRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLM
Sbjct: 1 MHGHSRNGQAHVPRRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLM 60
Query: 61 IFSAAFLVSWLFFGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNG 120
IFSAAFLVSWLFFGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNG
Sbjct: 61 IFSAAFLVSWLFFGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNG 120
Query: 121 FLGAFLFSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKK 180
FLGAFLFSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKK
Sbjct: 121 FLGAFLFSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKK 180
Query: 181 RAQTLLFSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQR 240
RAQTLLFSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQR
Sbjct: 181 RAQTLLFSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQR 240
Query: 241 DLNVGYDIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMT 300
DLNVGYDIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMT
Sbjct: 241 DLNVGYDIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMT 300
Query: 301 TQARSSYLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESKITV 360
TQARSSYLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESKITV
Sbjct: 301 TQARSSYLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESKITV 360
Query: 361 LPAPPPPPSAFCYENELALMSQEEEEMEEEAAAAAAVAAGLGLEAGSKEEAGIIRMLEFG 420
LPAPPPPPSAFCYENELALMSQEEEEMEEEAAAAAAVAAGLGLEAGSKEEAGIIRMLEFG
Sbjct: 361 LPAPPPPPSAFCYENELALMSQEEEEMEEEAAAAAAVAAGLGLEAGSKEEAGIIRMLEFG 420
Query: 421 SHLDLERMQASLPLDNISYRRESAI 445
SHLDLERMQASLPLDNISYRRESAI
Sbjct: 421 SHLDLERMQASLPLDNISYRRESAI 445
>gi|23110982 potassium inwardly-rectifying channel, subfamily J,
member 12 [Homo sapiens]
Length = 433
Score = 555 bits (1429), Expect = e-158
Identities = 284/440 (64%), Positives = 337/440 (76%), Gaps = 40/440 (9%)
Query: 7 NGQAHVPRRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAF 66
NG+ H RR+ RNRFVKKNGQCN+ FAN+ KSQRY+AD+FTTCVD RWRYML+IFS AF
Sbjct: 33 NGKVHT-RRRCRNRFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAF 91
Query: 67 LVSWLFFGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFL 126
L SWL FG++FW IA HGDLE PA G G PC+M V+GF+ AFL
Sbjct: 92 LASWLLFGIIFWVIAVAHGDLE----------PAEGRGRT------PCVMQVHGFMAAFL 135
Query: 127 FSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLL 186
FS+ETQTTIGYG RCVTEECP+AV VV QSIVGC+IDSFMIG IMAKMARPKKRAQTLL
Sbjct: 136 FSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLL 195
Query: 187 FSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGY 246
FSH+AV+++RDGKLCLMWRVGNLRKSHIVEAHVRAQLIKP +T+EGEY+PLDQ D++VG+
Sbjct: 196 FSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGF 255
Query: 247 DIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSS 306
D GLDRIFLVSPI I+HEIDE SPL+G+ +++LE++DFEIVVILEGMVEATAMTTQARSS
Sbjct: 256 DKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSS 315
Query: 307 YLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESKITVLPAPPP 366
YLA+EILWGHRFEPV+FEEK+ YK+DYS FHKTYEV TP CSA++L E+K + P
Sbjct: 316 YLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAKDLVENKFLL-----P 370
Query: 367 PPSAFCYENELALMSQEEEEMEEEAAAAAAVAAGLGLEAGSKEEAGIIRMLEFGSHLDLE 426
++FCYENELA +S++EE+ EA ++ L + D +
Sbjct: 371 SANSFCYENELAFLSRDEED-----------------EADGDQDGRSRDGLSPQARHDFD 413
Query: 427 RMQA-SLPLDNISYRRESAI 445
R+QA L+ YRRES I
Sbjct: 414 RLQAGGGVLEQRPYRRESEI 433
>gi|239758082 PREDICTED: similar to thyrotoxic periodic paralysis
susceptibility ion channel [Homo sapiens]
Length = 433
Score = 547 bits (1409), Expect = e-156
Identities = 268/380 (70%), Positives = 315/380 (82%), Gaps = 22/380 (5%)
Query: 7 NGQAHVPRRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAF 66
NG+ H RR+ RNRFVKKNGQCN+ FAN+ KSQRY+AD+FTTCVD RWRYML+IFS AF
Sbjct: 33 NGKVHT-RRRCRNRFVKKNGQCNIAFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAF 91
Query: 67 LVSWLFFGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFL 126
L SWL FG++FW IA HGDLE PA G G PC+M V+GF+ AFL
Sbjct: 92 LASWLLFGVIFWVIAVAHGDLE----------PAEGHGRT------PCVMQVHGFMAAFL 135
Query: 127 FSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLL 186
FS+ETQTTIGYG RCVTEEC +AV VV QSIVGC+IDSFMIG IMAKMARPKKRA TLL
Sbjct: 136 FSIETQTTIGYGLRCVTEECLVAVFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAHTLL 195
Query: 187 FSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGY 246
FSH+AV+++RDGKLCLMWRVGNLRKSHIVEAHVRAQLIKP +T+EGEY+PLDQ D++VG+
Sbjct: 196 FSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGF 255
Query: 247 DIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSS 306
D GLDRIFLVSPI I+HEIDE SPL+G+ +++LE++DFEIVVILEGMVEATAMTTQARSS
Sbjct: 256 DKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSS 315
Query: 307 YLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESKITVLPAPPP 366
YLA+EILWGHRFEPV+FEEK+ YK+DYS FHKTYEV TP CSA++L E+K + P
Sbjct: 316 YLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAKDLVENKFLL-----P 370
Query: 367 PPSAFCYENELALMSQEEEE 386
++FCYENELA +S++EE+
Sbjct: 371 SANSFCYENELAFLSRDEED 390
>gi|239757993 PREDICTED: similar to inward rectifying K+ channel
negative regulator Kir2.2v isoform 1 [Homo sapiens]
Length = 432
Score = 524 bits (1350), Expect = e-149
Identities = 272/440 (61%), Positives = 330/440 (75%), Gaps = 41/440 (9%)
Query: 7 NGQAHVPRRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAF 66
NG+ H RR+ NRFVKKNGQCN+ FAN+ KSQRY+ADIFTTCVD RWRYML+IFS AF
Sbjct: 33 NGKVHT-RRRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAF 91
Query: 67 LVSWLFFGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFL 126
L SWL FG++FW IA HGDLE PA G G PC+M V+GF+ AFL
Sbjct: 92 LASWLLFGVIFWVIAVAHGDLE----------PAEGRGRT------PCVMQVHGFMAAFL 135
Query: 127 FSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLL 186
FS++TQ TI YG RCVTEECP+AV VV QSIVGC+I+SFMIG IMAKM RPKKRAQTLL
Sbjct: 136 FSIKTQNTISYGLRCVTEECPVAVFMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLL 195
Query: 187 FSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGY 246
FSH+AV+++RDGKLC MWRVGNLRKSHIVEAHVRAQLIKP +T+EGEY+PLDQ D++VG+
Sbjct: 196 FSHNAVVALRDGKLCFMWRVGNLRKSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGF 255
Query: 247 DIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSS 306
D GLD FLVSPI I+HEIDE SPL+G+ +++L+ +DFEIV+ILEG+VEATAMTTQARSS
Sbjct: 256 DKGLDHSFLVSPITILHEIDEASPLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSS 315
Query: 307 YLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESKITVLPAPPP 366
YLA+EILWGHRFEPV+F EK+ YK+DY FHKTYEV TP CSA++L E+K + P
Sbjct: 316 YLANEILWGHRFEPVLF-EKNQYKIDYLHFHKTYEVPSTPRCSAKDLVENKFLL-----P 369
Query: 367 PPSAFCYENELALMSQEEEEMEEEAAAAAAVAAGLGLEAGSKEEAGIIRMLEFGSHLDLE 426
++FCY+NELA +S++EE+ + G + G E G+I + D +
Sbjct: 370 RANSFCYKNELAFLSRDEEDEAD------------GDQDGRSRE-GLIPQ----ARHDFD 412
Query: 427 RMQA-SLPLDNISYRRESAI 445
R+QA L+ YRRES I
Sbjct: 413 RLQAGGGVLEQRPYRRESEI 432
>gi|239757991 PREDICTED: similar to inward rectifying K+ channel
negative regulator Kir2.2v isoform 2 [Homo sapiens]
Length = 534
Score = 524 bits (1350), Expect = e-149
Identities = 272/440 (61%), Positives = 330/440 (75%), Gaps = 41/440 (9%)
Query: 7 NGQAHVPRRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAF 66
NG+ H RR+ NRFVKKNGQCN+ FAN+ KSQRY+ADIFTTCVD RWRYML+IFS AF
Sbjct: 135 NGKVHT-RRRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAF 193
Query: 67 LVSWLFFGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFL 126
L SWL FG++FW IA HGDLE PA G G PC+M V+GF+ AFL
Sbjct: 194 LASWLLFGVIFWVIAVAHGDLE----------PAEGRGRT------PCVMQVHGFMAAFL 237
Query: 127 FSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLL 186
FS++TQ TI YG RCVTEECP+AV VV QSIVGC+I+SFMIG IMAKM RPKKRAQTLL
Sbjct: 238 FSIKTQNTISYGLRCVTEECPVAVFMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLL 297
Query: 187 FSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGY 246
FSH+AV+++RDGKLC MWRVGNLRKSHIVEAHVRAQLIKP +T+EGEY+PLDQ D++VG+
Sbjct: 298 FSHNAVVALRDGKLCFMWRVGNLRKSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGF 357
Query: 247 DIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSS 306
D GLD FLVSPI I+HEIDE SPL+G+ +++L+ +DFEIV+ILEG+VEATAMTTQARSS
Sbjct: 358 DKGLDHSFLVSPITILHEIDEASPLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSS 417
Query: 307 YLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESKITVLPAPPP 366
YLA+EILWGHRFEPV+F EK+ YK+DY FHKTYEV TP CSA++L E+K + P
Sbjct: 418 YLANEILWGHRFEPVLF-EKNQYKIDYLHFHKTYEVPSTPRCSAKDLVENKFLL-----P 471
Query: 367 PPSAFCYENELALMSQEEEEMEEEAAAAAAVAAGLGLEAGSKEEAGIIRMLEFGSHLDLE 426
++FCY+NELA +S++EE+ + G + G E G+I + D +
Sbjct: 472 RANSFCYKNELAFLSRDEEDEAD------------GDQDGRSRE-GLIPQ----ARHDFD 514
Query: 427 RMQA-SLPLDNISYRRESAI 445
R+QA L+ YRRES I
Sbjct: 515 RLQAGGGVLEQRPYRRESEI 534
>gi|239751249 PREDICTED: hypothetical protein XP_002347768 [Homo
sapiens]
Length = 432
Score = 524 bits (1350), Expect = e-149
Identities = 272/440 (61%), Positives = 330/440 (75%), Gaps = 41/440 (9%)
Query: 7 NGQAHVPRRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAF 66
NG+ H RR+ NRFVKKNGQCN+ FAN+ KSQRY+ADIFTTCVD RWRYML+IFS AF
Sbjct: 33 NGKVHT-RRRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAF 91
Query: 67 LVSWLFFGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFL 126
L SWL FG++FW IA HGDLE PA G G PC+M V+GF+ AFL
Sbjct: 92 LASWLLFGVIFWVIAVAHGDLE----------PAEGRGRT------PCVMQVHGFMAAFL 135
Query: 127 FSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLL 186
FS++TQ TI YG RCVTEECP+AV VV QSIVGC+I+SFMIG IMAKM RPKKRAQTLL
Sbjct: 136 FSIKTQNTISYGLRCVTEECPVAVFMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLL 195
Query: 187 FSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGY 246
FSH+AV+++RDGKLC MWRVGNLRKSHIVEAHVRAQLIKP +T+EGEY+PLDQ D++VG+
Sbjct: 196 FSHNAVVALRDGKLCFMWRVGNLRKSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGF 255
Query: 247 DIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSS 306
D GLD FLVSPI I+HEIDE SPL+G+ +++L+ +DFEIV+ILEG+VEATAMTTQARSS
Sbjct: 256 DKGLDHSFLVSPITILHEIDEASPLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSS 315
Query: 307 YLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESKITVLPAPPP 366
YLA+EILWGHRFEPV+F EK+ YK+DY FHKTYEV TP CSA++L E+K + P
Sbjct: 316 YLANEILWGHRFEPVLF-EKNQYKIDYLHFHKTYEVPSTPRCSAKDLVENKFLL-----P 369
Query: 367 PPSAFCYENELALMSQEEEEMEEEAAAAAAVAAGLGLEAGSKEEAGIIRMLEFGSHLDLE 426
++FCY+NELA +S++EE+ + G + G E G+I + D +
Sbjct: 370 RANSFCYKNELAFLSRDEEDEAD------------GDQDGRSRE-GLIPQ----ARHDFD 412
Query: 427 RMQA-SLPLDNISYRRESAI 445
R+QA L+ YRRES I
Sbjct: 413 RLQAGGGVLEQRPYRRESEI 432
>gi|4504835 potassium inwardly-rectifying channel J2 [Homo sapiens]
Length = 427
Score = 523 bits (1347), Expect = e-148
Identities = 266/440 (60%), Positives = 325/440 (73%), Gaps = 45/440 (10%)
Query: 7 NGQAHVPRRKR-RNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAA 65
NG++ V R++ R+RFVKK+G CNV F N+ K QRY+ADIFTTCVD RWR+ML+IF A
Sbjct: 32 NGKSKVHTRQQCRSRFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLA 91
Query: 66 FLVSWLFFGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAF 125
F++SWLFFG +FW IA HGDL+AS K C+ VN F AF
Sbjct: 92 FVLSWLFFGCVFWLIALLHGDLDASK------------------EGKACVSEVNSFTAAF 133
Query: 126 LFSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTL 185
LFS+ETQTTIGYGFRCVT+ECP+AV VV QSIVGC+ID+F+IG +MAKMA+PKKR +TL
Sbjct: 134 LFSIETQTTIGYGFRCVTDECPIAVFMVVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETL 193
Query: 186 LFSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVG 245
+FSH+AVI++RDGKLCLMWRVGNLRKSH+VEAHVRAQL+K +T EGEY+PLDQ D+NVG
Sbjct: 194 VFSHNAVIAMRDGKLCLMWRVGNLRKSHLVEAHVRAQLLKSRITSEGEYIPLDQIDINVG 253
Query: 246 YDIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARS 305
+D G+DRIFLVSPI IVHEIDEDSPLY + K+++++ DFEIVVILEGMVEATAMTTQ RS
Sbjct: 254 FDSGIDRIFLVSPITIVHEIDEDSPLYDLSKQDIDNADFEIVVILEGMVEATAMTTQCRS 313
Query: 306 SYLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESKITVLPAPP 365
SYLA+EILWGHR+EPV+FEEK +YKVDYSRFHKTYEV TP CSAR+L E K + A
Sbjct: 314 SYLANEILWGHRYEPVLFEEKHYYKVDYSRFHKTYEVPNTPLCSARDLAEKKYILSNA-- 371
Query: 366 PPPSAFCYENELALMSQEEEEMEEEAAAAAAVAAGLGLEAGSKEEAGIIRMLEFGSHLDL 425
++FCYENE+AL S+EE++ E + + + +DL
Sbjct: 372 ---NSFCYENEVALTSKEEDDSENGVPESTST--------------------DTPPDIDL 408
Query: 426 ERMQASLPLDNISYRRESAI 445
QAS+PL+ RRES I
Sbjct: 409 HN-QASVPLEPRPLRRESEI 427
>gi|7019439 potassium inwardly-rectifying channel J14 [Homo sapiens]
Length = 436
Score = 479 bits (1234), Expect = e-135
Identities = 237/396 (59%), Positives = 293/396 (73%), Gaps = 26/396 (6%)
Query: 3 GHSRNGQAHVPRR----KRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYM 58
G RNG A P + +RR RFVKK+G CNV F NL + RY++D+FTTCVD RWR+M
Sbjct: 30 GLCRNGWAPAPVQSPVGRRRGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWM 89
Query: 59 LMIFSAAFLVSWLFFGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHV 118
++FS +FL SWL FGL FW IA HGDL AAP P PC HV
Sbjct: 90 CLLFSCSFLASWLLFGLAFWLIASLHGDL------------------AAPPPPAPCFSHV 131
Query: 119 NGFLGAFLFSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARP 178
FL AFLF++ETQT+IGYG R VTEECP AV AVV+Q I GCV+D+F++G +MAKMA+P
Sbjct: 132 ASFLAAFLFALETQTSIGYGVRSVTEECPAAVAAVVLQCIAGCVLDAFVVGAVMAKMAKP 191
Query: 179 KKRAQTLLFSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLD 238
KKR +TL+FS +AV+++RD +LCLMWRVGNLR+SH+VEAHVRAQL++P +T EGEY+PLD
Sbjct: 192 KKRNETLVFSENAVVALRDHRLCLMWRVGNLRRSHLVEAHVRAQLLQPRVTPEGEYIPLD 251
Query: 239 QRDLNVGYDIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATA 298
+D++VG+D G DRIFLVSPI IVHEID SPLY +G+ EL DFE+VVILEGMVEATA
Sbjct: 252 HQDVDVGFDGGTDRIFLVSPITIVHEIDSASPLYELGRAELARADFELVVILEGMVEATA 311
Query: 299 MTTQARSSYLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQE--- 355
MTTQ RSSYL E+LWGHRFEPV+F+ S Y+VDY FH+TYEV GTP CSA+EL E
Sbjct: 312 MTTQCRSSYLPGELLWGHRFEPVLFQRGSQYEVDYRHFHRTYEVPGTPVCSAKELDERAE 371
Query: 356 -SKITVLPAPPPPPSAFCYENELALMSQEEEEMEEE 390
+ ++ + P +AFCYENELAL +EE+ ++E
Sbjct: 372 QASHSLKSSFPGSLTAFCYENELALSCCQEEDEDDE 407
>gi|25777635 potassium inwardly-rectifying channel J14 [Homo
sapiens]
Length = 436
Score = 479 bits (1234), Expect = e-135
Identities = 237/396 (59%), Positives = 293/396 (73%), Gaps = 26/396 (6%)
Query: 3 GHSRNGQAHVPRR----KRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYM 58
G RNG A P + +RR RFVKK+G CNV F NL + RY++D+FTTCVD RWR+M
Sbjct: 30 GLCRNGWAPAPVQSPVGRRRGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWM 89
Query: 59 LMIFSAAFLVSWLFFGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHV 118
++FS +FL SWL FGL FW IA HGDL AAP P PC HV
Sbjct: 90 CLLFSCSFLASWLLFGLAFWLIASLHGDL------------------AAPPPPAPCFSHV 131
Query: 119 NGFLGAFLFSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARP 178
FL AFLF++ETQT+IGYG R VTEECP AV AVV+Q I GCV+D+F++G +MAKMA+P
Sbjct: 132 ASFLAAFLFALETQTSIGYGVRSVTEECPAAVAAVVLQCIAGCVLDAFVVGAVMAKMAKP 191
Query: 179 KKRAQTLLFSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLD 238
KKR +TL+FS +AV+++RD +LCLMWRVGNLR+SH+VEAHVRAQL++P +T EGEY+PLD
Sbjct: 192 KKRNETLVFSENAVVALRDHRLCLMWRVGNLRRSHLVEAHVRAQLLQPRVTPEGEYIPLD 251
Query: 239 QRDLNVGYDIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATA 298
+D++VG+D G DRIFLVSPI IVHEID SPLY +G+ EL DFE+VVILEGMVEATA
Sbjct: 252 HQDVDVGFDGGTDRIFLVSPITIVHEIDSASPLYELGRAELARADFELVVILEGMVEATA 311
Query: 299 MTTQARSSYLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQE--- 355
MTTQ RSSYL E+LWGHRFEPV+F+ S Y+VDY FH+TYEV GTP CSA+EL E
Sbjct: 312 MTTQCRSSYLPGELLWGHRFEPVLFQRGSQYEVDYRHFHRTYEVPGTPVCSAKELDERAE 371
Query: 356 -SKITVLPAPPPPPSAFCYENELALMSQEEEEMEEE 390
+ ++ + P +AFCYENELAL +EE+ ++E
Sbjct: 372 QASHSLKSSFPGSLTAFCYENELALSCCQEEDEDDE 407
>gi|24797141 potassium inwardly-rectifying channel J5 [Homo sapiens]
Length = 419
Score = 389 bits (1000), Expect = e-108
Identities = 191/389 (49%), Positives = 275/389 (70%), Gaps = 21/389 (5%)
Query: 15 RKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFG 74
+K R R+++K+G+CNV+ N+ ++ RY++D+FTT VD +WR+ L++F+ + V+WLFFG
Sbjct: 47 KKPRQRYMEKSGKCNVHHGNVQ-ETYRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFG 105
Query: 75 LLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTT 134
++W IA+ GDL+ PC+ +++GF+ AFLFS+ET+TT
Sbjct: 106 FIWWLIAYIRGDLD----------------HVGDQEWIPCVENLSGFVSAFLFSIETETT 149
Query: 135 IGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVIS 194
IGYGFR +TE+CP +I ++VQ+I+G ++++FM+G + K+++PKKRA+TL+FS++AVIS
Sbjct: 150 IGYGFRVITEKCPEGIILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVIS 209
Query: 195 VRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIF 254
+RD KLCLM+RVG+LR SHIVEA +RA+LIK T+EGE++PL+Q D+NVG+D G DR+F
Sbjct: 210 MRDEKLCLMFRVGDLRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLF 269
Query: 255 LVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEILW 314
LVSP+II HEI++ SP + M + +L E+FE+VVILEGMVEAT MT QARSSY+ +E+LW
Sbjct: 270 LVSPLIISHEINQKSPFWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLW 329
Query: 315 GHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESK---ITVLPAPPPPPSAF 371
GHRF PV+ EK Y+VDY+ FH TYE TP C A+EL E K + P PP
Sbjct: 330 GHRFTPVLTLEKGFYEVDYNTFHDTYE-TNTPSCCAKELAEMKREGRLLQYLPSPPLLGG 388
Query: 372 CYENELALMSQEEEEMEEEAAAAAAVAAG 400
C E L +++ EE E + + A G
Sbjct: 389 CAEAGLDAEAEQNEEDEPKGLGGSREARG 417
>gi|25121970 potassium inwardly-rectifying channel subfamily J9
[Homo sapiens]
Length = 393
Score = 382 bits (982), Expect = e-106
Identities = 197/403 (48%), Positives = 275/403 (68%), Gaps = 34/403 (8%)
Query: 8 GQAHVPRRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFL 67
GQ PRR+ R R+V+K+G+CNV N+ ++ RY+ D+FTT VD +WR L+ F A+
Sbjct: 11 GQEEPPRRRGRQRYVEKDGRCNVQQGNV-RETYRYLTDLFTTLVDLQWRLSLLFFVLAYA 69
Query: 68 VSWLFFGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLF 127
++WLFFG ++W IA+ GDLE A PC+ ++NGF+ AFLF
Sbjct: 70 LTWLFFGAIWWLIAYGRGDLEH----------------LEDTAWTPCVNNLNGFVAAFLF 113
Query: 128 SVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLF 187
S+ET+TTIGYG R +T++CP ++ +++Q+I+G ++++FM+G + K+++P KRA TL+F
Sbjct: 114 SIETETTIGYGHRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVF 173
Query: 188 SHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYD 247
S HAV+S+RDG+LCLM+RVG+LR SHIVEA +RA+LI+ T EGE++PL Q DL+VG+D
Sbjct: 174 SSHAVVSLRDGRLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFD 233
Query: 248 IGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSY 307
G DR+FLVSP++I HEID SP + + LE +DFEIVVILEGMVEAT MT QARSSY
Sbjct: 234 TGDDRLFLVSPLVISHEIDAASPFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSY 293
Query: 308 LASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESKITVLPAPPPP 367
L E+LWGHRF V+ E Y+VDY+ FH+T+EV TP CSAREL E+ +
Sbjct: 294 LVDEVLWGHRFTSVLTLEDGFYEVDYASFHETFEVP-TPSCSARELAEAAARL------- 345
Query: 368 PSAFCYENELALMSQEEEEMEEEAAAAAAVAAGLGLEAGSKEE 410
A Y ++ S+ +E++EEE A G G EAG+ +E
Sbjct: 346 -DAHLY---WSIPSRLDEKVEEEGA-----GEGAGGEAGADKE 379
>gi|4504843 potassium inwardly-rectifying channel J6 [Homo sapiens]
Length = 423
Score = 380 bits (975), Expect = e-105
Identities = 193/387 (49%), Positives = 272/387 (70%), Gaps = 21/387 (5%)
Query: 14 RRKRR-NRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLF 72
R KR+ R+V+K+G+CNV+ N+ ++ RY+ DIFTT VD +WR+ L+IF + V+WLF
Sbjct: 48 RTKRKIQRYVRKDGKCNVHHGNV-RETYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLF 106
Query: 73 FGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQ 132
FG+++W IA+ GD++ + PC+ ++NGF+ AFLFS+ET+
Sbjct: 107 FGMIWWLIAYIRGDMDH----------------IEDPSWTPCVTNLNGFVSAFLFSIETE 150
Query: 133 TTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAV 192
TTIGYG+R +T++CP +I +++QS++G ++++FM+G + K+++PKKRA+TL+FS HAV
Sbjct: 151 TTIGYGYRVITDKCPEGIILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAV 210
Query: 193 ISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDR 252
IS+RDGKLCLM+RVG+LR SHIVEA +RA+LIK T EGE++PL+Q D+NVGY G DR
Sbjct: 211 ISMRDGKLCLMFRVGDLRNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDR 270
Query: 253 IFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEI 312
+FLVSP+II HEI++ SP + + K +L E+ EIVVILEGMVEAT MT QARSSY+ SEI
Sbjct: 271 LFLVSPLIISHEINQQSPFWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEI 330
Query: 313 LWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQE-SKITVLPAPPPPPSAF 371
LWG+RF PV+ E Y+VDY+ FH+TYE + TP SA+EL E + LP S
Sbjct: 331 LWGYRFTPVLTLEDGFYEVDYNSFHETYETS-TPSLSAKELAELASRAELPLSWSVSSKL 389
Query: 372 CYENELALMSQEEEEMEEEAAAAAAVA 398
EL +EE+ +EE+ VA
Sbjct: 390 NQHAELE-TEEEEKNLEEQTERNGDVA 415
>gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens]
Length = 501
Score = 358 bits (918), Expect = 7e-99
Identities = 177/364 (48%), Positives = 245/364 (67%), Gaps = 17/364 (4%)
Query: 3 GHSRNGQAHVPRRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIF 62
G ++ Q + +K+R RFV KNG+CNV NL +++ RY++D+FTT VD +WR+ L IF
Sbjct: 28 GPGQDPQQQLVPKKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIF 87
Query: 63 SAAFLVSWLFFGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFL 122
+ V+WLF ++W IA+ GDL A G P C+ +V F
Sbjct: 88 ILTYTVAWLFMASMWWVIAYTRGDLNK-----------AHVGNYTP-----CVANVYNFP 131
Query: 123 GAFLFSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRA 182
AFLF +ET+ TIGYG+R +T++CP +I + QSI+G ++D+F+IG + KM++PKKRA
Sbjct: 132 SAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRA 191
Query: 183 QTLLFSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDL 242
+TL+FS HAVIS+RDGKL LM+RVGNLR SH+V A +R +L+K T EGE+LPLDQ +L
Sbjct: 192 ETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLEL 251
Query: 243 NVGYDIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQ 302
+VG+ G D++FLVSP+ I H ID SP Y + + +++E FEIVVILEG+VE T MT Q
Sbjct: 252 DVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQ 311
Query: 303 ARSSYLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESKITVLP 362
AR+SY E+LWGHRF PV+ E+ +KVDYS+FH T+EV TP S +E +E + P
Sbjct: 312 ARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVP-TPPYSVKEQEEMLLMSSP 370
Query: 363 APPP 366
P
Sbjct: 371 LIAP 374
>gi|4826802 potassium inwardly-rectifying channel J8 [Homo sapiens]
Length = 424
Score = 329 bits (843), Expect = 4e-90
Identities = 167/341 (48%), Positives = 235/341 (68%), Gaps = 10/341 (2%)
Query: 15 RKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFG 74
R + RF+ K+G CN+ N+ + R++ DIFTT VD +WR+ L+IF+ +FL SWL F
Sbjct: 30 RLPKARFIAKSGACNLAHKNIREQG-RFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLLFA 88
Query: 75 LLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTT 134
+++W +AF HGD+ A + +G +G + C+ +V F AFLFS+E Q T
Sbjct: 89 IMWWLVAFAHGDIYAY--MEKSGMEKSG------LESTVCVTNVRSFTSAFLFSIEVQVT 140
Query: 135 IGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVIS 194
IG+G R +TEECPLA+ +++Q+IVG +I++ M+G I K A+ +RA+TL+FS HAVI+
Sbjct: 141 IGFGGRMMTEECPLAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIA 200
Query: 195 VRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIF 254
VR+GKLC M+RVG+LRKS I+ A VR Q++K T EGE +P+ Q D+ V I + IF
Sbjct: 201 VRNGKLCFMFRVGDLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIF 260
Query: 255 LVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEILW 314
LV+P+II H ID+ SPLY + +L ++D E++VILEG+VE T +TTQAR+SY+A EI W
Sbjct: 261 LVAPLIICHVIDKRSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQW 320
Query: 315 GHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQE 355
GHRF +V EE+ Y VDYS+F T +VA P CSAREL E
Sbjct: 321 GHRFVSIVTEEEGVYSVDYSKFGNTVKVA-APRCSARELDE 360
>gi|62388888 potassium inwardly-rectifying channel J11 [Homo
sapiens]
Length = 390
Score = 328 bits (841), Expect = 6e-90
Identities = 167/342 (48%), Positives = 229/342 (66%), Gaps = 20/342 (5%)
Query: 15 RKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFG 74
R+RR RFV K G CNV N+ + R++ D+FTT VD +W + L+IF+ +FL SWL F
Sbjct: 29 RQRRARFVSKKGNCNVAHKNIREQG-RFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFA 87
Query: 75 LLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTT 134
+ +W IAF HGDL S G +PC+ ++ F AFLFS+E Q T
Sbjct: 88 MAWWLIAFAHGDLAPSEGTA-----------------EPCVTSIHSFSSAFLFSIEVQVT 130
Query: 135 IGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVIS 194
IG+G R VTEECPLA++ ++VQ+IVG +I++ M+G I K A+ +RA+TL+FS HAVI+
Sbjct: 131 IGFGGRMVTEECPLAILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIA 190
Query: 195 VRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIF 254
+R G+LC M RVG+LRKS I+ A + Q+++ + EGE +PL Q D+ + +G + IF
Sbjct: 191 LRHGRLCFMLRVGDLRKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIF 250
Query: 255 LVSPIIIVHEIDEDSPLYGMGKEEL-ESEDFEIVVILEGMVEATAMTTQARSSYLASEIL 313
LV+P+II H ID +SPLY + +L +D EI+VILEG+VE T +TTQAR+SYLA EIL
Sbjct: 251 LVAPLIIYHVIDANSPLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEIL 310
Query: 314 WGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQE 355
WG RF P+V EE Y VDYS+F T +V TP C+AR+L E
Sbjct: 311 WGQRFVPIVAEEDGRYSVDYSKFGNTVKVP-TPLCTARQLDE 351
>gi|8923823 potassium inwardly-rectifying channel J16 [Homo sapiens]
Length = 418
Score = 322 bits (824), Expect = 6e-88
Identities = 162/354 (45%), Positives = 239/354 (67%), Gaps = 26/354 (7%)
Query: 14 RRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFF 73
+R+ R R + K+G CNVYF ++ + Y+ DIFTT VDT+WR+M +IFS ++++SWL F
Sbjct: 29 KRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIF 88
Query: 74 GLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQT 133
G +FW IAF HGDL P + PC+ +V+ F GAFLFS+ETQT
Sbjct: 89 GSVFWLIAFHHGDLLNDPDIT------------------PCVDNVHSFTGAFLFSLETQT 130
Query: 134 TIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVI 193
TIGYG+RCVTEEC +AV+ V++QSI+ C+I++F+IG +AKMA +KRAQT+ FS+ A+I
Sbjct: 131 TIGYGYRCVTEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALI 190
Query: 194 SVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRI 253
+RDGKLCLMWR+G+ R +H+VE VRAQL++ EG + + +DL + D+I
Sbjct: 191 GMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLK----LVNDQI 245
Query: 254 FLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEIL 313
LV+P+ IVHEID +SPLY + ++ + ++FEI+V ++T + Q+RSSY+ EIL
Sbjct: 246 ILVTPVTIVHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREIL 305
Query: 314 WGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSAREL--QESKITVLPAPP 365
WGHRF V+ ++ +YKV+ +F + EV P CSA++L ++ ++ + APP
Sbjct: 306 WGHRFNDVLEVKRKYYKVNCLQFEGSVEVY-APFCSAKQLDWKDQQLHIEKAPP 358
>gi|25777630 potassium inwardly-rectifying channel J16 [Homo
sapiens]
Length = 418
Score = 322 bits (824), Expect = 6e-88
Identities = 162/354 (45%), Positives = 239/354 (67%), Gaps = 26/354 (7%)
Query: 14 RRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFF 73
+R+ R R + K+G CNVYF ++ + Y+ DIFTT VDT+WR+M +IFS ++++SWL F
Sbjct: 29 KRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIF 88
Query: 74 GLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQT 133
G +FW IAF HGDL P + PC+ +V+ F GAFLFS+ETQT
Sbjct: 89 GSVFWLIAFHHGDLLNDPDIT------------------PCVDNVHSFTGAFLFSLETQT 130
Query: 134 TIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVI 193
TIGYG+RCVTEEC +AV+ V++QSI+ C+I++F+IG +AKMA +KRAQT+ FS+ A+I
Sbjct: 131 TIGYGYRCVTEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALI 190
Query: 194 SVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRI 253
+RDGKLCLMWR+G+ R +H+VE VRAQL++ EG + + +DL + D+I
Sbjct: 191 GMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLK----LVNDQI 245
Query: 254 FLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEIL 313
LV+P+ IVHEID +SPLY + ++ + ++FEI+V ++T + Q+RSSY+ EIL
Sbjct: 246 ILVTPVTIVHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREIL 305
Query: 314 WGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSAREL--QESKITVLPAPP 365
WGHRF V+ ++ +YKV+ +F + EV P CSA++L ++ ++ + APP
Sbjct: 306 WGHRFNDVLEVKRKYYKVNCLQFEGSVEVY-APFCSAKQLDWKDQQLHIEKAPP 358
>gi|25777628 potassium inwardly-rectifying channel J16 [Homo
sapiens]
Length = 418
Score = 322 bits (824), Expect = 6e-88
Identities = 162/354 (45%), Positives = 239/354 (67%), Gaps = 26/354 (7%)
Query: 14 RRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFF 73
+R+ R R + K+G CNVYF ++ + Y+ DIFTT VDT+WR+M +IFS ++++SWL F
Sbjct: 29 KRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIF 88
Query: 74 GLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQT 133
G +FW IAF HGDL P + PC+ +V+ F GAFLFS+ETQT
Sbjct: 89 GSVFWLIAFHHGDLLNDPDIT------------------PCVDNVHSFTGAFLFSLETQT 130
Query: 134 TIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVI 193
TIGYG+RCVTEEC +AV+ V++QSI+ C+I++F+IG +AKMA +KRAQT+ FS+ A+I
Sbjct: 131 TIGYGYRCVTEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALI 190
Query: 194 SVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRI 253
+RDGKLCLMWR+G+ R +H+VE VRAQL++ EG + + +DL + D+I
Sbjct: 191 GMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLK----LVNDQI 245
Query: 254 FLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEIL 313
LV+P+ IVHEID +SPLY + ++ + ++FEI+V ++T + Q+RSSY+ EIL
Sbjct: 246 ILVTPVTIVHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREIL 305
Query: 314 WGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSAREL--QESKITVLPAPP 365
WGHRF V+ ++ +YKV+ +F + EV P CSA++L ++ ++ + APP
Sbjct: 306 WGHRFNDVLEVKRKYYKVNCLQFEGSVEVY-APFCSAKQLDWKDQQLHIEKAPP 358
>gi|24497471 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 312 bits (800), Expect = 3e-85
Identities = 159/336 (47%), Positives = 225/336 (66%), Gaps = 18/336 (5%)
Query: 16 KRRNRFVKKNGQCNVYFANLSNKSQR-YMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFG 74
++R R V K+G+CN+ F N+ +S+ + DI+TT +D +WRY + IF AFL SW FFG
Sbjct: 18 RQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFG 77
Query: 75 LLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTT 134
LL++ +A+ H DL P+A PC+ ++NG AFLFS+ETQ T
Sbjct: 78 LLWYAVAYIHKDLPEFH-------PSANH--------TPCVENINGLTSAFLFSLETQVT 122
Query: 135 IGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVIS 194
IGYGFRCVTE+C A+ ++ QSI+G +I+SFM G I+AK++RPKKRA+T+ FS +AVIS
Sbjct: 123 IGYGFRCVTEQCATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVIS 182
Query: 195 VRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIF 254
R GKLCL+ RV NLRKS ++ +H+ +L+K +T EGE + LDQ ++N D G + +F
Sbjct: 183 KRGGKLCLLIRVANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLF 242
Query: 255 LVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEILW 314
+SP+ I H ID +SP + M E L +DFE+VV L+G VE+T+ T Q R+SY+ E+LW
Sbjct: 243 FISPLTIYHVIDHNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLW 302
Query: 315 GHRFEPVVFEEK-SHYKVDYSRFHKTYEVAGTPCCS 349
G+RF P+V + K Y+VD+ F KT EV TP C+
Sbjct: 303 GYRFAPIVSKTKEGKYRVDFHNFSKTVEVE-TPHCA 337
>gi|24497467 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 312 bits (800), Expect = 3e-85
Identities = 159/336 (47%), Positives = 225/336 (66%), Gaps = 18/336 (5%)
Query: 16 KRRNRFVKKNGQCNVYFANLSNKSQR-YMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFG 74
++R R V K+G+CN+ F N+ +S+ + DI+TT +D +WRY + IF AFL SW FFG
Sbjct: 18 RQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFG 77
Query: 75 LLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTT 134
LL++ +A+ H DL P+A PC+ ++NG AFLFS+ETQ T
Sbjct: 78 LLWYAVAYIHKDLPEFH-------PSANH--------TPCVENINGLTSAFLFSLETQVT 122
Query: 135 IGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVIS 194
IGYGFRCVTE+C A+ ++ QSI+G +I+SFM G I+AK++RPKKRA+T+ FS +AVIS
Sbjct: 123 IGYGFRCVTEQCATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVIS 182
Query: 195 VRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIF 254
R GKLCL+ RV NLRKS ++ +H+ +L+K +T EGE + LDQ ++N D G + +F
Sbjct: 183 KRGGKLCLLIRVANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLF 242
Query: 255 LVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEILW 314
+SP+ I H ID +SP + M E L +DFE+VV L+G VE+T+ T Q R+SY+ E+LW
Sbjct: 243 FISPLTIYHVIDHNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLW 302
Query: 315 GHRFEPVVFEEK-SHYKVDYSRFHKTYEVAGTPCCS 349
G+RF P+V + K Y+VD+ F KT EV TP C+
Sbjct: 303 GYRFAPIVSKTKEGKYRVDFHNFSKTVEVE-TPHCA 337
>gi|4504837 potassium inwardly-rectifying channel J1 isoform a [Homo
sapiens]
Length = 391
Score = 312 bits (800), Expect = 3e-85
Identities = 159/336 (47%), Positives = 225/336 (66%), Gaps = 18/336 (5%)
Query: 16 KRRNRFVKKNGQCNVYFANLSNKSQR-YMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFG 74
++R R V K+G+CN+ F N+ +S+ + DI+TT +D +WRY + IF AFL SW FFG
Sbjct: 37 RQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFG 96
Query: 75 LLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTT 134
LL++ +A+ H DL P+A PC+ ++NG AFLFS+ETQ T
Sbjct: 97 LLWYAVAYIHKDLPEFH-------PSANH--------TPCVENINGLTSAFLFSLETQVT 141
Query: 135 IGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVIS 194
IGYGFRCVTE+C A+ ++ QSI+G +I+SFM G I+AK++RPKKRA+T+ FS +AVIS
Sbjct: 142 IGYGFRCVTEQCATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVIS 201
Query: 195 VRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIF 254
R GKLCL+ RV NLRKS ++ +H+ +L+K +T EGE + LDQ ++N D G + +F
Sbjct: 202 KRGGKLCLLIRVANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLF 261
Query: 255 LVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEILW 314
+SP+ I H ID +SP + M E L +DFE+VV L+G VE+T+ T Q R+SY+ E+LW
Sbjct: 262 FISPLTIYHVIDHNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLW 321
Query: 315 GHRFEPVVFEEK-SHYKVDYSRFHKTYEVAGTPCCS 349
G+RF P+V + K Y+VD+ F KT EV TP C+
Sbjct: 322 GYRFAPIVSKTKEGKYRVDFHNFSKTVEVE-TPHCA 356
>gi|148539892 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 312 bits (800), Expect = 3e-85
Identities = 159/336 (47%), Positives = 225/336 (66%), Gaps = 18/336 (5%)
Query: 16 KRRNRFVKKNGQCNVYFANLSNKSQR-YMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFG 74
++R R V K+G+CN+ F N+ +S+ + DI+TT +D +WRY + IF AFL SW FFG
Sbjct: 18 RQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFG 77
Query: 75 LLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTT 134
LL++ +A+ H DL P+A PC+ ++NG AFLFS+ETQ T
Sbjct: 78 LLWYAVAYIHKDLPEFH-------PSANH--------TPCVENINGLTSAFLFSLETQVT 122
Query: 135 IGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVIS 194
IGYGFRCVTE+C A+ ++ QSI+G +I+SFM G I+AK++RPKKRA+T+ FS +AVIS
Sbjct: 123 IGYGFRCVTEQCATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVIS 182
Query: 195 VRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIF 254
R GKLCL+ RV NLRKS ++ +H+ +L+K +T EGE + LDQ ++N D G + +F
Sbjct: 183 KRGGKLCLLIRVANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLF 242
Query: 255 LVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEILW 314
+SP+ I H ID +SP + M E L +DFE+VV L+G VE+T+ T Q R+SY+ E+LW
Sbjct: 243 FISPLTIYHVIDHNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLW 302
Query: 315 GHRFEPVVFEEK-SHYKVDYSRFHKTYEVAGTPCCS 349
G+RF P+V + K Y+VD+ F KT EV TP C+
Sbjct: 303 GYRFAPIVSKTKEGKYRVDFHNFSKTVEVE-TPHCA 337
>gi|24497473 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 312 bits (800), Expect = 3e-85
Identities = 159/336 (47%), Positives = 225/336 (66%), Gaps = 18/336 (5%)
Query: 16 KRRNRFVKKNGQCNVYFANLSNKSQR-YMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFG 74
++R R V K+G+CN+ F N+ +S+ + DI+TT +D +WRY + IF AFL SW FFG
Sbjct: 18 RQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFG 77
Query: 75 LLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTT 134
LL++ +A+ H DL P+A PC+ ++NG AFLFS+ETQ T
Sbjct: 78 LLWYAVAYIHKDLPEFH-------PSANH--------TPCVENINGLTSAFLFSLETQVT 122
Query: 135 IGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVIS 194
IGYGFRCVTE+C A+ ++ QSI+G +I+SFM G I+AK++RPKKRA+T+ FS +AVIS
Sbjct: 123 IGYGFRCVTEQCATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVIS 182
Query: 195 VRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIF 254
R GKLCL+ RV NLRKS ++ +H+ +L+K +T EGE + LDQ ++N D G + +F
Sbjct: 183 KRGGKLCLLIRVANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLF 242
Query: 255 LVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEILW 314
+SP+ I H ID +SP + M E L +DFE+VV L+G VE+T+ T Q R+SY+ E+LW
Sbjct: 243 FISPLTIYHVIDHNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLW 302
Query: 315 GHRFEPVVFEEK-SHYKVDYSRFHKTYEVAGTPCCS 349
G+RF P+V + K Y+VD+ F KT EV TP C+
Sbjct: 303 GYRFAPIVSKTKEGKYRVDFHNFSKTVEVE-TPHCA 337
>gi|25121966 potassium inwardly-rectifying channel, subfamily J,
member 10 [Homo sapiens]
Length = 379
Score = 268 bits (684), Expect = 1e-71
Identities = 136/329 (41%), Positives = 206/329 (62%), Gaps = 19/329 (5%)
Query: 17 RRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFGLL 76
RR R + K+G+ NV ++++K Y+ D++TT +D +WRY L++FSA F +W FG++
Sbjct: 26 RRRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWFLFGVV 85
Query: 77 FWCIAFFHGDL-EASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTTI 135
++ +A HGDL E P P PC++ V+ GAFLFS+E+QTTI
Sbjct: 86 WYLVAVAHGDLLELDP----------------PANHTPCVVQVHTLTGAFLFSLESQTTI 129
Query: 136 GYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVISV 195
GYGFR ++EECPLA++ ++ Q ++ +++ F+ GT +AK+ARPKKRA+T+ FS HAV++
Sbjct: 130 GYGFRYISEECPLAIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVAS 189
Query: 196 RDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIFL 255
+GK CLM RV N+RKS ++ V +L++ + T+EGE + L+Q ++ D D FL
Sbjct: 190 HNGKPCLMIRVANMRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFL 249
Query: 256 VSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEILWG 315
+ P+ H +DE SPL + E DFE+V+IL G VE+T+ T Q R+SYL EILWG
Sbjct: 250 ILPLTFYHVVDETSPLKDLPLRSGEG-DFELVLILSGTVESTSATCQVRTSYLPEEILWG 308
Query: 316 HRFEPVV-FEEKSHYKVDYSRFHKTYEVA 343
+ F P + Y D+S F + +VA
Sbjct: 309 YEFTPAISLSASGKYIADFSLFDQVVKVA 337
>gi|21361127 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 266 bits (681), Expect = 2e-71
Identities = 134/336 (39%), Positives = 210/336 (62%), Gaps = 19/336 (5%)
Query: 15 RKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFG 74
+ R R + K+G NV + Y+ D++TT +D +WRY L +F+A F+++W FG
Sbjct: 23 KANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFG 82
Query: 75 LLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTT 134
++++ IAF HGDLE PG P + PCIM V+ GAFLFS+E+QTT
Sbjct: 83 VIYYAIAFIHGDLE--PGEPISNHT-------------PCIMKVDSLTGAFLFSLESQTT 127
Query: 135 IGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVIS 194
IGYG R +TEECP A+ +V Q ++ +I+ F+ GT +AK+ARPKKRA+T+ FSH AVI+
Sbjct: 128 IGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVIT 187
Query: 195 VRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIF 254
++GKLCL+ +V N+RKS +++ + +L++ ++T+EGE + L+Q + D + F
Sbjct: 188 KQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPF 247
Query: 255 LVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEILW 314
L+ P+ H +DE SPL + + L+ ++FE+VV+L VE+T+ Q+R+SY+ EI W
Sbjct: 248 LILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYW 307
Query: 315 GHRFEPVV-FEEKSHYKVDYSRFHKTYEVAGTPCCS 349
G F PVV + Y D+S+F ++ +P C+
Sbjct: 308 GFEFVPVVSLSKNGKYVADFSQFE---QIRKSPDCT 340
>gi|25777640 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 266 bits (681), Expect = 2e-71
Identities = 134/336 (39%), Positives = 210/336 (62%), Gaps = 19/336 (5%)
Query: 15 RKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFG 74
+ R R + K+G NV + Y+ D++TT +D +WRY L +F+A F+++W FG
Sbjct: 23 KANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFG 82
Query: 75 LLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTT 134
++++ IAF HGDLE PG P + PCIM V+ GAFLFS+E+QTT
Sbjct: 83 VIYYAIAFIHGDLE--PGEPISNHT-------------PCIMKVDSLTGAFLFSLESQTT 127
Query: 135 IGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVIS 194
IGYG R +TEECP A+ +V Q ++ +I+ F+ GT +AK+ARPKKRA+T+ FSH AVI+
Sbjct: 128 IGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVIT 187
Query: 195 VRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIF 254
++GKLCL+ +V N+RKS +++ + +L++ ++T+EGE + L+Q + D + F
Sbjct: 188 KQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPF 247
Query: 255 LVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEILW 314
L+ P+ H +DE SPL + + L+ ++FE+VV+L VE+T+ Q+R+SY+ EI W
Sbjct: 248 LILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYW 307
Query: 315 GHRFEPVV-FEEKSHYKVDYSRFHKTYEVAGTPCCS 349
G F PVV + Y D+S+F ++ +P C+
Sbjct: 308 GFEFVPVVSLSKNGKYVADFSQFE---QIRKSPDCT 340
>gi|25777638 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 266 bits (681), Expect = 2e-71
Identities = 134/336 (39%), Positives = 210/336 (62%), Gaps = 19/336 (5%)
Query: 15 RKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFG 74
+ R R + K+G NV + Y+ D++TT +D +WRY L +F+A F+++W FG
Sbjct: 23 KANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFG 82
Query: 75 LLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTT 134
++++ IAF HGDLE PG P + PCIM V+ GAFLFS+E+QTT
Sbjct: 83 VIYYAIAFIHGDLE--PGEPISNHT-------------PCIMKVDSLTGAFLFSLESQTT 127
Query: 135 IGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVIS 194
IGYG R +TEECP A+ +V Q ++ +I+ F+ GT +AK+ARPKKRA+T+ FSH AVI+
Sbjct: 128 IGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVIT 187
Query: 195 VRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIF 254
++GKLCL+ +V N+RKS +++ + +L++ ++T+EGE + L+Q + D + F
Sbjct: 188 KQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPF 247
Query: 255 LVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEILW 314
L+ P+ H +DE SPL + + L+ ++FE+VV+L VE+T+ Q+R+SY+ EI W
Sbjct: 248 LILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYW 307
Query: 315 GHRFEPVV-FEEKSHYKVDYSRFHKTYEVAGTPCCS 349
G F PVV + Y D+S+F ++ +P C+
Sbjct: 308 GFEFVPVVSLSKNGKYVADFSQFE---QIRKSPDCT 340
>gi|156119627 potassium inwardly-rectifying channel J13 [Homo
sapiens]
Length = 360
Score = 176 bits (445), Expect = 5e-44
Identities = 114/337 (33%), Positives = 173/337 (51%), Gaps = 23/337 (6%)
Query: 16 KRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFGL 75
+R R V K+G + + + Y+ D + +D RWR+M+++FSA+F+V WL F +
Sbjct: 15 QRYRRMVTKDGHSTLQMDG-AQRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAV 73
Query: 76 LFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTTI 135
L++ +A +GDLE P P C+ ++ F AF FS+ETQ TI
Sbjct: 74 LWYVLAEMNGDLELDHDAP-------------PENHTICVKYITSFTAAFSFSLETQLTI 120
Query: 136 GYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVISV 195
GYG + +CP A+ + +Q ++G ++++F+ G +AK+ARPK RA ++ F+ AV++
Sbjct: 121 GYGTMFPSGDCPSAIALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAH 180
Query: 196 RDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYD-IGLDRI- 253
DGK L+++V N R S + V A L QE E L Q ++ D I D
Sbjct: 181 MDGKPNLIFQVANTRPSPLTSVRVSAVLY-----QERENGKLYQTSVDFHLDGISSDECP 235
Query: 254 FLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEIL 313
F + P+ H I SPL + + E S FE+VV L M E T Q R+SYL SEI+
Sbjct: 236 FFIFPLTYYHSITPSSPLATLLQHENPSH-FELVVFLSAMQEGTGEICQRRTSYLPSEIM 294
Query: 314 WGHRFEPVVFE-EKSHYKVDYSRFHKTYEVAGTPCCS 349
H F ++ K Y++ F KT TP S
Sbjct: 295 LHHCFASLLTRGSKGEYQIKMENFDKTVPEFPTPLVS 331
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 35.0 bits (79), Expect = 0.14
Identities = 24/60 (40%), Positives = 28/60 (46%), Gaps = 9/60 (15%)
Query: 374 ENELALMSQEEEEMEEEAAAAAAVAAGLGLEAGSKEEAGIIRMLEFGSHLDLERMQASLP 433
E E +EEEE EEEAAAA A+ LG +GS E GS +R Q P
Sbjct: 755 EEEEEEEEEEEEEEEEEAAAAVALGEVLGPRSGSSSE---------GSERSTDRSQEGAP 805
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.137 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,683,609
Number of Sequences: 37866
Number of extensions: 857339
Number of successful extensions: 7395
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 55
Number of HSP's successfully gapped in prelim test: 44
Number of HSP's that attempted gapping in prelim test: 7141
Number of HSP's gapped (non-prelim): 190
length of query: 445
length of database: 18,247,518
effective HSP length: 105
effective length of query: 340
effective length of database: 14,271,588
effective search space: 4852339920
effective search space used: 4852339920
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.