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Search of human proteins with 13270473
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13270473 beta-neoendorphin-dynorphin preproprotein [Homo
sapiens]
(254 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13270473 beta-neoendorphin-dynorphin preproprotein [Homo sapi... 516 e-147
gi|208879446 proenkephalin [Homo sapiens] 91 1e-18
gi|5453876 proenkephalin [Homo sapiens] 91 1e-18
gi|5453922 prepronociceptin [Homo sapiens] 35 0.082
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 32 0.70
gi|55769587 probable nucleolar complex protein 14 [Homo sapiens] 30 1.6
gi|90093355 jumonji C domain containing histone demethylase 1 ho... 30 1.6
gi|209862994 MAP-kinase activating death domain-containing prote... 30 2.0
gi|18860873 MAP-kinase activating death domain-containing protei... 30 2.0
gi|110349767 calcium channel, voltage-dependent, L type, alpha 1... 30 2.7
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 30 2.7
gi|21264592 ArfGAP with RhoGAP domain, ankyrin repeat and PH dom... 30 2.7
gi|51172610 Rho guanine nucleotide exchange factor (GEF) 5-like ... 29 3.5
gi|188497718 catenin, alpha 3 [Homo sapiens] 29 4.5
gi|188497716 catenin, alpha 3 [Homo sapiens] 29 4.5
gi|21389423 junctional sarcoplasmic reticulum protein 1 [Homo sa... 29 4.5
gi|53832007 calcium channel, voltage-dependent, L type, alpha 1F... 28 5.9
gi|19920317 cytoskeleton-associated protein 4 [Homo sapiens] 28 7.7
gi|239741018 PREDICTED: hypothetical protein XP_002342056 [Homo ... 28 7.7
>gi|13270473 beta-neoendorphin-dynorphin preproprotein [Homo
sapiens]
Length = 254
Score = 516 bits (1330), Expect = e-147
Identities = 254/254 (100%), Positives = 254/254 (100%)
Query: 1 MAWQGLVLAACLLMFPSTTADCLSRCSLCAVKTQDGPKPINPLICSLQCQAALLPSEEWE 60
MAWQGLVLAACLLMFPSTTADCLSRCSLCAVKTQDGPKPINPLICSLQCQAALLPSEEWE
Sbjct: 1 MAWQGLVLAACLLMFPSTTADCLSRCSLCAVKTQDGPKPINPLICSLQCQAALLPSEEWE 60
Query: 61 RCQSFLSFFTPSTLGLNDKEDLGSKSVGEGPYSELAKLSGSFLKELEKSKFLPSISTKEN 120
RCQSFLSFFTPSTLGLNDKEDLGSKSVGEGPYSELAKLSGSFLKELEKSKFLPSISTKEN
Sbjct: 61 RCQSFLSFFTPSTLGLNDKEDLGSKSVGEGPYSELAKLSGSFLKELEKSKFLPSISTKEN 120
Query: 121 TLSKSLEEKLRGLSDGFREGAESELMRDAQLNDGAMETGTLYLAEEDPKEQVKRYGGFLR 180
TLSKSLEEKLRGLSDGFREGAESELMRDAQLNDGAMETGTLYLAEEDPKEQVKRYGGFLR
Sbjct: 121 TLSKSLEEKLRGLSDGFREGAESELMRDAQLNDGAMETGTLYLAEEDPKEQVKRYGGFLR 180
Query: 181 KYPKRSSEVAGEGDGDSMGHEDLYKRYGGFLRRIRPKLKWDNQKRYGGFLRRQFKVVTRS 240
KYPKRSSEVAGEGDGDSMGHEDLYKRYGGFLRRIRPKLKWDNQKRYGGFLRRQFKVVTRS
Sbjct: 181 KYPKRSSEVAGEGDGDSMGHEDLYKRYGGFLRRIRPKLKWDNQKRYGGFLRRQFKVVTRS 240
Query: 241 QEDPNAYSGELFDA 254
QEDPNAYSGELFDA
Sbjct: 241 QEDPNAYSGELFDA 254
>gi|208879446 proenkephalin [Homo sapiens]
Length = 267
Score = 90.5 bits (223), Expect = 1e-18
Identities = 79/252 (31%), Positives = 120/252 (47%), Gaps = 29/252 (11%)
Query: 14 MFPSTTADCLSRCSLCAVKTQDGPKPINPLICSLQCQAALLPSEEWERCQSFLSFFTP-- 71
+ + A+C C+ C+ + P IN L C ++C+ L + WE C+ L P
Sbjct: 18 LLATVRAECSQDCATCSYRLVR-PADINFLACVMECEGKLPSLKIWETCKELLQLSKPEL 76
Query: 72 -----STLGLNDKEDLGSKSVGEGPYSELAKLSGSFLKELEKSKFLPSISTKENTLSKSL 126
STL N K + + Y K G F+K++++ P +E S+ L
Sbjct: 77 PQDGTSTLRENSKPE--ESHLLAKRYGGFMKRYGGFMKKMDE--LYPMEPEEEANGSEIL 132
Query: 127 EEKLRGLSDGFREGAESELMRDAQLNDGAMETG-----TLYLAEEDPKEQV-KRYGGFLR 180
++ G E +S L + L +ETG + + D +E+V KRYGGF+R
Sbjct: 133 AKRYGGFMKKDAEEDDS-LANSSDLLKELLETGDNRERSHHQDGSDNEEEVSKRYGGFMR 191
Query: 181 KYPKRSSEVAGEGDGDSMGHEDLYKRYGGFLRRI-RPKLKWDNQKRYGGFLRRQFKVVTR 239
KRS ++ E ++L KRYGGF+RR+ RP+ D QKRYGGFL+R F
Sbjct: 192 GL-KRSPQLEDEA-------KELQKRYGGFMRRVGRPEWWMDYQKRYGGFLKR-FAEALP 242
Query: 240 SQEDPNAYSGEL 251
S E+ +YS E+
Sbjct: 243 SDEEGESYSKEV 254
>gi|5453876 proenkephalin [Homo sapiens]
Length = 267
Score = 90.5 bits (223), Expect = 1e-18
Identities = 79/252 (31%), Positives = 120/252 (47%), Gaps = 29/252 (11%)
Query: 14 MFPSTTADCLSRCSLCAVKTQDGPKPINPLICSLQCQAALLPSEEWERCQSFLSFFTP-- 71
+ + A+C C+ C+ + P IN L C ++C+ L + WE C+ L P
Sbjct: 18 LLATVRAECSQDCATCSYRLVR-PADINFLACVMECEGKLPSLKIWETCKELLQLSKPEL 76
Query: 72 -----STLGLNDKEDLGSKSVGEGPYSELAKLSGSFLKELEKSKFLPSISTKENTLSKSL 126
STL N K + + Y K G F+K++++ P +E S+ L
Sbjct: 77 PQDGTSTLRENSKPE--ESHLLAKRYGGFMKRYGGFMKKMDE--LYPMEPEEEANGSEIL 132
Query: 127 EEKLRGLSDGFREGAESELMRDAQLNDGAMETG-----TLYLAEEDPKEQV-KRYGGFLR 180
++ G E +S L + L +ETG + + D +E+V KRYGGF+R
Sbjct: 133 AKRYGGFMKKDAEEDDS-LANSSDLLKELLETGDNRERSHHQDGSDNEEEVSKRYGGFMR 191
Query: 181 KYPKRSSEVAGEGDGDSMGHEDLYKRYGGFLRRI-RPKLKWDNQKRYGGFLRRQFKVVTR 239
KRS ++ E ++L KRYGGF+RR+ RP+ D QKRYGGFL+R F
Sbjct: 192 GL-KRSPQLEDEA-------KELQKRYGGFMRRVGRPEWWMDYQKRYGGFLKR-FAEALP 242
Query: 240 SQEDPNAYSGEL 251
S E+ +YS E+
Sbjct: 243 SDEEGESYSKEV 254
>gi|5453922 prepronociceptin [Homo sapiens]
Length = 176
Score = 34.7 bits (78), Expect = 0.082
Identities = 23/95 (24%), Positives = 40/95 (42%), Gaps = 2/95 (2%)
Query: 150 QLNDGAME--TGTLYLAEEDPKEQVKRYGGFLRKYPKRSSEVAGEGDGDSMGHEDLYKRY 207
QL+ A E LY + ++R + ++ G + M + L KR+
Sbjct: 71 QLSPAAPEHVAAALYQPRASEMQHLRRMPRVRSLFQEQEEPEPGMEEAGEMEQKQLQKRF 130
Query: 208 GGFLRRIRPKLKWDNQKRYGGFLRRQFKVVTRSQE 242
GGF + K NQKR+ F+R+ + +S +
Sbjct: 131 GGFTGARKSARKLANQKRFSEFMRQYLVLSMQSSQ 165
Score = 32.3 bits (72), Expect = 0.41
Identities = 14/56 (25%), Positives = 23/56 (41%)
Query: 12 LLMFPSTTADCLSRCSLCAVKTQDGPKPINPLICSLQCQAALLPSEEWERCQSFLS 67
L +F S + C C C K + +C L+C+ + PS W C ++
Sbjct: 11 LSLFSSVFSSCQRDCLTCQEKLHPALDSFDLEVCILECEEKVFPSPLWTPCTKVMA 66
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 31.6 bits (70), Expect = 0.70
Identities = 22/76 (28%), Positives = 36/76 (47%), Gaps = 2/76 (2%)
Query: 80 EDLGSKSVGEGPYSE--LAKLSGSFLKELEKSKFLPSISTKENTLSKSLEEKLRGLSDGF 137
ED SK + E E +A+ S +E EK+K L I K+ + LEE+L+
Sbjct: 991 EDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTR 1050
Query: 138 REGAESELMRDAQLND 153
+E +++ D + D
Sbjct: 1051 QELEKAKRKLDGETTD 1066
>gi|55769587 probable nucleolar complex protein 14 [Homo sapiens]
Length = 857
Score = 30.4 bits (67), Expect = 1.6
Identities = 39/164 (23%), Positives = 64/164 (39%), Gaps = 35/164 (21%)
Query: 57 EEWERCQSFLSFFTPSTLGLNDKE-------DLGSKSVG----------EGPYSELAKLS 99
++W+ Q+ LS TP + + KE D+ + +G +ELAK
Sbjct: 223 QDWKEIQTLLSHKTPKSENRDKKEKPKPDAYDMMVRELGFEMKAQPSNRMKTEAELAKEE 282
Query: 100 GSFLKELEKSKFLPSISTKEN-TLSKSLEEKLRGLSDGFREGAESELMRDAQLNDGAMET 158
L++LE + + E+ + K L+DGF + + R DG M
Sbjct: 283 QEHLRKLEAERLRRMLGKDEDENVKKPKHMSADDLNDGF--VLDKDDRRLLSYKDGKMN- 339
Query: 159 GTLYLAEEDPKEQVKRYGGFLRKYPKRSSEVAGEGDGDSMGHED 202
EED +E+ + + S + E +GDS G ED
Sbjct: 340 -----VEEDVQEEQSK---------EASDPESNEEEGDSSGGED 369
>gi|90093355 jumonji C domain containing histone demethylase 1
homolog D [Homo sapiens]
Length = 941
Score = 30.4 bits (67), Expect = 1.6
Identities = 28/124 (22%), Positives = 52/124 (41%), Gaps = 24/124 (19%)
Query: 96 AKLSGSFLKELEKSKFLPSISTKENTLSKSLEEKLRGLSDGFREGAESELMRDAQLNDGA 155
+KL+G F K L+ S +P K+N L L +++D +
Sbjct: 551 SKLNGKFNKHLQPSSTVPEWRAKDNDLRLLL--------------TNGRIIKDER---QP 593
Query: 156 METGTLYLAEEDPKEQVKRYGGFLRKYPKRSSEVAGEGDGDSMGHEDLYKRYGGFLRRIR 215
+LY A+ + +E +R +K + E +G + + HE+ K GF R++
Sbjct: 594 FADQSLYTADSENEEDKRR----TKKAKMKIEESSGV---EGVEHEESQKPLNGFFTRVK 646
Query: 216 PKLK 219
+L+
Sbjct: 647 SELR 650
>gi|209862994 MAP-kinase activating death domain-containing protein
isoform d [Homo sapiens]
Length = 1647
Score = 30.0 bits (66), Expect = 2.0
Identities = 41/158 (25%), Positives = 64/158 (40%), Gaps = 21/158 (13%)
Query: 84 SKSVGEGPYSE----LAKLSGSFL-KELEKSKFLPSISTKENTLSKSLEEKLRGLSDGFR 138
S + G+GP E LA G+ E+E + +I K ++L S++EKL G
Sbjct: 1216 SSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLKPSIKEKLAGSPIRTS 1275
Query: 139 EGA-------ESELMRDA-----QLNDGAMETGTLYLAEEDPKEQVKRYGGFLRKYPKRS 186
E E L RD QL D AMET ++ +Q++ F +
Sbjct: 1276 EDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQMQ----FWEDAFLDA 1331
Query: 187 SEVAGEGDGDSMGHEDLYKRYGGFLRRIRPKLKWDNQK 224
+ EG G G +++ RY R +L+ D +
Sbjct: 1332 VMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDR 1369
>gi|18860873 MAP-kinase activating death domain-containing protein
isoform g [Homo sapiens]
Length = 1581
Score = 30.0 bits (66), Expect = 2.0
Identities = 41/158 (25%), Positives = 64/158 (40%), Gaps = 21/158 (13%)
Query: 84 SKSVGEGPYSE----LAKLSGSFL-KELEKSKFLPSISTKENTLSKSLEEKLRGLSDGFR 138
S + G+GP E LA G+ E+E + +I K ++L S++EKL G
Sbjct: 1216 SSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLKPSIKEKLAGSPIRTS 1275
Query: 139 EGA-------ESELMRDA-----QLNDGAMETGTLYLAEEDPKEQVKRYGGFLRKYPKRS 186
E E L RD QL D AMET ++ +Q++ F +
Sbjct: 1276 EDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQMQ----FWEDAFLDA 1331
Query: 187 SEVAGEGDGDSMGHEDLYKRYGGFLRRIRPKLKWDNQK 224
+ EG G G +++ RY R +L+ D +
Sbjct: 1332 VMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDR 1369
>gi|110349767 calcium channel, voltage-dependent, L type, alpha 1S
subunit [Homo sapiens]
Length = 1873
Score = 29.6 bits (65), Expect = 2.7
Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 8/73 (10%)
Query: 95 LAKLSGSFLKELEKSKFLPSISTKENTLSK-SLEEKLRGLSDGFREG--AESELMRDAQ- 150
L LSG F KE EK+K S T + K L+E LRG +G + E R+ +
Sbjct: 330 LGVLSGEFTKEREKAK---SRGTFQKLREKQQLDEDLRGYMSWITQGEVMDVEDFREGKL 386
Query: 151 -LNDGAMETGTLY 162
L++G +T +LY
Sbjct: 387 SLDEGGSDTESLY 399
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 29.6 bits (65), Expect = 2.7
Identities = 20/80 (25%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Query: 100 GSFLKELEKSKFLPSISTKENTLS-KSLEEKLRGLSDGFR--EGAESELMRDAQLNDGAM 156
G+++++L K + PS+ NT++ + L+EK L + R E +SE+ + + +
Sbjct: 189 GTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKL 248
Query: 157 ETGTLYLAEEDPKEQVKRYG 176
E L L ++ + + R G
Sbjct: 249 ERAQLLLPQQQLQVEADRLG 268
>gi|21264592 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
[Homo sapiens]
Length = 1704
Score = 29.6 bits (65), Expect = 2.7
Identities = 15/37 (40%), Positives = 21/37 (56%), Gaps = 6/37 (16%)
Query: 153 DGAMETGTLY------LAEEDPKEQVKRYGGFLRKYP 183
D A+ T LY L +D KE++K+YG F+R P
Sbjct: 1197 DDALLTKELYPYWISALDTQDDKERIKKYGAFIRSLP 1233
>gi|51172610 Rho guanine nucleotide exchange factor (GEF) 5-like
[Homo sapiens]
Length = 484
Score = 29.3 bits (64), Expect = 3.5
Identities = 39/173 (22%), Positives = 71/173 (41%), Gaps = 9/173 (5%)
Query: 34 QDGPKPINPLICSLQCQAALLPSEEWERCQSFLSFFTPSTLGLNDKEDLGSKSVGEGPYS 93
++G + P SL +A P E WE L+ TL +L + + + +
Sbjct: 80 KEGSADVEPNQESLVAEACDTP-EHWEAVPQSLAGRQARTLA---PPELWACPI-QSEHL 134
Query: 94 ELAKLSGSFLKELEKSKFLPSISTKENTLSKSLEEKLRGLSDGFREGAES---ELMRDAQ 150
++A S E E+ +F P +++ ++ EE+ + + S E +
Sbjct: 135 DMAPFSSDLGSEEEEVEFWPGLTSLTLGSGQAEEEEETSSDNSGQTRYYSPCEEHPAETN 194
Query: 151 LNDGAMETGTLYLAEEDPKEQVKRYGGFLRKYPKRSSEVAGEGDGDSMGHEDL 203
N+GA E+GT+ EE P E+++ G L + E G+ + G L
Sbjct: 195 QNEGA-ESGTIRQGEELPSEELQESQGLLHPQEVQVLEEQGQQEAGFRGEGTL 246
>gi|188497718 catenin, alpha 3 [Homo sapiens]
Length = 895
Score = 28.9 bits (63), Expect = 4.5
Identities = 21/66 (31%), Positives = 32/66 (48%), Gaps = 1/66 (1%)
Query: 83 GSKSVGEGPYSELAKLSGSFLKELEKSKFLPSISTKENTLSKSLEEKLRGLSDGFREGAE 142
G +++ P + A L GS L ELE L ++ E + SLE++L + G A+
Sbjct: 258 GIQNMTTPPEPQAATL-GSALDELENLIVLNPLTVTEEEIRPSLEKRLEAIISGAALLAD 316
Query: 143 SELMRD 148
S RD
Sbjct: 317 SSCTRD 322
>gi|188497716 catenin, alpha 3 [Homo sapiens]
Length = 895
Score = 28.9 bits (63), Expect = 4.5
Identities = 21/66 (31%), Positives = 32/66 (48%), Gaps = 1/66 (1%)
Query: 83 GSKSVGEGPYSELAKLSGSFLKELEKSKFLPSISTKENTLSKSLEEKLRGLSDGFREGAE 142
G +++ P + A L GS L ELE L ++ E + SLE++L + G A+
Sbjct: 258 GIQNMTTPPEPQAATL-GSALDELENLIVLNPLTVTEEEIRPSLEKRLEAIISGAALLAD 316
Query: 143 SELMRD 148
S RD
Sbjct: 317 SSCTRD 322
>gi|21389423 junctional sarcoplasmic reticulum protein 1 [Homo
sapiens]
Length = 331
Score = 28.9 bits (63), Expect = 4.5
Identities = 16/59 (27%), Positives = 30/59 (50%)
Query: 127 EEKLRGLSDGFREGAESELMRDAQLNDGAMETGTLYLAEEDPKEQVKRYGGFLRKYPKR 185
E ++R G RE AE++ + A+ + LA+ PKE+ +R G ++ P++
Sbjct: 194 EAEVRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPRK 252
>gi|53832007 calcium channel, voltage-dependent, L type, alpha 1F
subunit [Homo sapiens]
Length = 1977
Score = 28.5 bits (62), Expect = 5.9
Identities = 20/59 (33%), Positives = 27/59 (45%), Gaps = 3/59 (5%)
Query: 95 LAKLSGSFLKELEKSKFLPSISTKENTLSKSLEEKLRGLSDGFREGAESELMRDAQLND 153
L LSG F KE EK+K + + +EE LRG D + E + M D +D
Sbjct: 368 LGVLSGEFSKEREKAKARGDFQKQRE--KQQMEEDLRGYLDWITQAEELD-MEDPSADD 423
>gi|19920317 cytoskeleton-associated protein 4 [Homo sapiens]
Length = 602
Score = 28.1 bits (61), Expect = 7.7
Identities = 26/104 (25%), Positives = 46/104 (44%), Gaps = 12/104 (11%)
Query: 79 KEDLGSKSVGEGP-----YSE-LAKLSGSFLKELE------KSKFLPSISTKENTLSKSL 126
K+DL K+V +G SE L KL LK+L K ++ ENT+ + L
Sbjct: 182 KQDLTEKAVKQGESEVSRISEVLQKLQNEILKDLSDGIHVVKDARERDFTSLENTVEERL 241
Query: 127 EEKLRGLSDGFREGAESELMRDAQLNDGAMETGTLYLAEEDPKE 170
E + ++D E + ++ND + +L +E + ++
Sbjct: 242 TELTKSINDNIAIFTEVQKRSQKEINDMKAKVASLEESEGNKQD 285
>gi|239741018 PREDICTED: hypothetical protein XP_002342056 [Homo
sapiens]
Length = 566
Score = 28.1 bits (61), Expect = 7.7
Identities = 18/55 (32%), Positives = 29/55 (52%), Gaps = 1/55 (1%)
Query: 36 GPKPINPLICSLQCQA-ALLPSEEWERCQSFLSFFTPSTLGLNDKEDLGSKSVGE 89
GP + P + SL+ +A AL+ + C++ LS + L DK+ G +VGE
Sbjct: 242 GPGTVVPELRSLKPEAQALITQGLYSHCRALLSQLPDTGAPLEDKDTQGLLAVGE 296
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.134 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,488,715
Number of Sequences: 37866
Number of extensions: 498601
Number of successful extensions: 1439
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1378
Number of HSP's gapped (non-prelim): 26
length of query: 254
length of database: 18,247,518
effective HSP length: 100
effective length of query: 154
effective length of database: 14,460,918
effective search space: 2226981372
effective search space used: 2226981372
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.